Light-Science & Applications最新文献_第10页

Alleviating NIR-II emission quenching in ring-fused fluorophore via manipulating dimer populations for superior fluorescence imaging 通过操纵二聚体群体获得优越的荧光成像，减轻环融合荧光团中NIR-II发射猝灭

Light-Science & Applications Pub Date : 2025-03-04 DOI: 10.1038/s41377-025-01787-0

Xiaofei Miao, Mingxuan Jia, Xianwei Weng, Jie Zhang, Yonghui Pan, Hui Zhao, Zhongzheng Yu, Quli Fan, Wenbo Hu

{"title":"Alleviating NIR-II emission quenching in ring-fused fluorophore via manipulating dimer populations for superior fluorescence imaging","authors":"Xiaofei Miao, Mingxuan Jia, Xianwei Weng, Jie Zhang, Yonghui Pan, Hui Zhao, Zhongzheng Yu, Quli Fan, Wenbo Hu","doi":"10.1038/s41377-025-01787-0","DOIUrl":"https://doi.org/10.1038/s41377-025-01787-0","url":null,"abstract":"Emission quenching resulting from fluorophore aggregation has long been a significant challenge in optimizing emission-based technologies, such as fluorescence imaging and optoelectronic devices. Alleviating this quenching in aggregates is crucial, yet progress is impeded by the limited understanding of the nature and impact of aggregates on emission. Here, we elucidate the critical role of dimeric aggregate (dimer) in alleviating second near-infrared (NIR-II, 900-1700 nm) emission quenching from ring-fused fluorophore 4F for superior fluorescence imaging. Spectral decomposition and molecular dynamics simulations demonstrate the predominance of dimer populations in 4F aggregates. Notably, dimers exhibit significantly weaker emission but intense intermolecular nonradiative (interNR) decay compared to monomers, as demonstrated by ultrafast spectra and quantum calculation. Therefore, the predominant population of dimers with weak emission and pronounced interNR feature underlies the emission quenching in 4F aggregates. This discovery guides the preparation of ultrabright NIR-II 4F nanofluorophore (4F NP3s) by decreasing dimer populations, which show 5-fold greater NIR-II brightness than indocyanine green, enabling superior resolution in visualizing blood vessels. This work offers valuable insights into aggregation-caused quenching, with broad implications extending far beyond NIR-II fluorescence imaging.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chip-integrated quantum signature network over 200 km 超过200公里的芯片集成量子签名网络

Light-Science & Applications Pub Date : 2025-03-04 DOI: 10.1038/s41377-025-01775-4

Yongqiang Du, Bing-Hong Li, Xin Hua, Xiao-Yu Cao, Zhengeng Zhao, Feng Xie, Zhenrong Zhang, Hua-Lei Yin, Xi Xiao, Kejin Wei

{"title":"Chip-integrated quantum signature network over 200 km","authors":"Yongqiang Du, Bing-Hong Li, Xin Hua, Xiao-Yu Cao, Zhengeng Zhao, Feng Xie, Zhenrong Zhang, Hua-Lei Yin, Xi Xiao, Kejin Wei","doi":"10.1038/s41377-025-01775-4","DOIUrl":"https://doi.org/10.1038/s41377-025-01775-4","url":null,"abstract":"The development of quantum networks is paramount towards practical and secure communications. Quantum digital signatures (QDS) offer an information-theoretically secure solution for ensuring data integrity, authenticity, and non-repudiation, rapidly growing from proof-of-concept to robust demonstrations. However, previous QDS systems relied on expensive and bulky optical equipment, limiting large-scale deployment and reconfigurable networking construction. Here, we introduce and verify a chip-based QDS network, placing the complicated and expensive measurement devices in the central relay while each user needs only a low-cost transmitter. We demonstrate the network with a three-node setup using an integrated encoder chip and decoder chip. By developing a 1-decoy-state one-time universal hashing-QDS protocol, we achieve a maximum signature rate of 0.0414 times per second for a 1 Mbit messages over fiber distances up to 200 km, surpassing all current state-of-the-art QDS experiments. This study validates the feasibility of chip-based QDS, paving the way for large-scale deployment and integration with existing fiber infrastructure.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unlocking the potential of up-conversion charging for rapid and high-resolution optical storage with phosphors 利用荧光粉释放上转换充电的潜力，实现快速、高分辨率的光存储

Light-Science & Applications Pub Date : 2025-03-04 DOI: 10.1038/s41377-025-01746-9

Lu Chen, Xueqing Liu, Feng Liu, Chuan Liao, Liangliang Zhang, Jiahua Zhang, Xiao-jun Wang, Yichun Liu

{"title":"Unlocking the potential of up-conversion charging for rapid and high-resolution optical storage with phosphors","authors":"Lu Chen, Xueqing Liu, Feng Liu, Chuan Liao, Liangliang Zhang, Jiahua Zhang, Xiao-jun Wang, Yichun Liu","doi":"10.1038/s41377-025-01746-9","DOIUrl":"https://doi.org/10.1038/s41377-025-01746-9","url":null,"abstract":"Current optical storage technologies utilizing phosphor media face challenges in achieving rapid and precise data recording with visible or infrared light, primarily due to the constraints of traditional charging techniques. Here, we introduce a cutting-edge method termed up-conversion charging (UCC) to address these challenges, enabling rapid and high-resolution data storage in phosphors. Our study focuses on the unique two-step ionization and non-linear charging characteristics of UCC in storage phosphors, specifically in a gallate composition Gd3Ga5O12:Cr3+. Remarkably, this technique enables data writing with high solution, requiring only 0.01 s of exposure per bit when utilizing a portable laser engraver equipped with visible-emitting diode lasers. The present strategy not only enhances recording efficiency but also ensures long-term data retention and superior rewritability. Moreover, we illustrate the versatility of UCC storage across various material systems through thermally- and optically-stimulated luminescence. Our outcomes highlight the transformative potential of the UCC method in advancing optical storage applications, offering significant improvements in the development of information storage solutions.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143538675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A large field of view 2- and 3-photon microscope 一个大视野的2和3光子显微镜

Light-Science & Applications Pub Date : 2025-02-27 DOI: 10.1038/s41377-025-01780-7

Jack Waters

引用次数: 0

Optical sorting: past, present and future 光学分类：过去、现在和未来

Light-Science & Applications Pub Date : 2025-02-27 DOI: 10.1038/s41377-024-01734-5

Meng Yang, Yuzhi Shi, Qinghua Song, Zeyong Wei, Xiong Dun, Zhiming Wang, Zhanshan Wang, Cheng-Wei Qiu, Hui Zhang, Xinbin Cheng

{"title":"Optical sorting: past, present and future","authors":"Meng Yang, Yuzhi Shi, Qinghua Song, Zeyong Wei, Xiong Dun, Zhiming Wang, Zhanshan Wang, Cheng-Wei Qiu, Hui Zhang, Xinbin Cheng","doi":"10.1038/s41377-024-01734-5","DOIUrl":"https://doi.org/10.1038/s41377-024-01734-5","url":null,"abstract":"Optical sorting combines optical tweezers with diverse techniques, including optical spectrum, artificial intelligence (AI) and immunoassay, to endow unprecedented capabilities in particle sorting. In comparison to other methods such as microfluidics, acoustics and electrophoresis, optical sorting offers appreciable advantages in nanoscale precision, high resolution, non-invasiveness, and is becoming increasingly indispensable in fields of biophysics, chemistry, and materials science. This review aims to offer a comprehensive overview of the history, development, and perspectives of various optical sorting techniques, categorised as passive and active sorting methods. To begin, we elucidate the fundamental physics and attributes of both conventional and exotic optical forces. We then explore sorting capabilities of active optical sorting, which fuses optical tweezers with a diversity of techniques, including Raman spectroscopy and machine learning. Afterwards, we reveal the essential roles played by deterministic light fields, configured with lens systems or metasurfaces, in the passive sorting of particles based on their varying sizes and shapes, sorting resolutions and speeds. We conclude with our vision of the most promising and futuristic directions, including AI-facilitated ultrafast and bio-morphology-selective sorting. It can be envisioned that optical sorting will inevitably become a revolutionary tool in scientific research and practical biomedical applications.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"49 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143507011","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3R-WS2 crystals as a breakthrough in compact entangled photon sources 3R-WS2晶体作为紧凑纠缠光子源的突破

Light-Science & Applications Pub Date : 2025-02-27 DOI: 10.1038/s41377-024-01688-8

引用次数: 0

Photon-triggered pyroptosis and ferroptosis dual-functional nanoplatform for cancer immunotherapy 用于癌症免疫治疗的光子触发焦亡和铁亡双功能纳米平台

Light-Science & Applications Pub Date : 2025-02-27 DOI: 10.1038/s41377-025-01757-6

Quansheng Cheng, Qingcheng Wang, Songnan Qu

引用次数: 0

Multiple defects renovation and phase reconstruction of reduced-dimensional perovskites via in situ chlorination for efficient deep-blue (454 nm) light-emitting diodes 高效深蓝（454nm）发光二极管用原位氯化法制备降维钙钛矿多缺陷修复和相重建

Light-Science & Applications Pub Date : 2025-02-26 DOI: 10.1038/s41377-025-01768-3

Mubing Yu, Tingxiao Qin, Gang Gao, Kelei Zu, Dongming Zhang, Nan Chen, Dengke Wang, Yong Hua, Hong Zhang, Yong-Biao Zhao, Jiaqi Zhu

{"title":"Multiple defects renovation and phase reconstruction of reduced-dimensional perovskites via in situ chlorination for efficient deep-blue (454 nm) light-emitting diodes","authors":"Mubing Yu, Tingxiao Qin, Gang Gao, Kelei Zu, Dongming Zhang, Nan Chen, Dengke Wang, Yong Hua, Hong Zhang, Yong-Biao Zhao, Jiaqi Zhu","doi":"10.1038/s41377-025-01768-3","DOIUrl":"https://doi.org/10.1038/s41377-025-01768-3","url":null,"abstract":"Deep-blue perovskite light-emitting diodes (PeLEDs) based on reduced-dimensional perovskites (RDPs) still face a few challenges including severe trap-assisted nonradiative recombination, sluggish exciton transfer, and undesirable bathochromic shift of the electroluminescence spectra, impeding the realization of high-performance PeLEDs. Herein, an in situ chlorination (isCl) post-treatment strategy was employed to regulate phase reconstruction and renovate multiple defects of RDPs, leading to superior carrier cooling of 0.88 ps, extraordinary exciton binding energy of 122.53 meV, and higher photoluminescence quantum yield of 60.9% for RDP films with deep-blue emission at 450 nm. The phase regulation is accomplished via fluorine-derived hydrogen bonds that suppress the formation of small-n phases. Multiple defects, including halide vacancies (shallow-state defects) and lead-chloride antisite defects (deep-state defects), are renovated via C=O coordination and hydroxy-group-derived hydrogen bonds. Consequently, deep-blue PeLEDs with a record maximum external quantum efficiency of 6.17% and stable electroluminescence at 454 nm were demonstrated, representing the best-performing deep-blue PeLEDs.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coherence synthesis in nonlinear optics 非线性光学中的相干合成

Light-Science & Applications Pub Date : 2025-02-26 DOI: 10.1038/s41377-025-01749-6

Zihao Pang, Ady Arie

{"title":"Coherence synthesis in nonlinear optics","authors":"Zihao Pang, Ady Arie","doi":"10.1038/s41377-025-01749-6","DOIUrl":"https://doi.org/10.1038/s41377-025-01749-6","url":null,"abstract":"It is commonly assumed that nonlinear frequency conversion requires lasers with high coherence; however, this assumption has constrained our broader understanding of coherence and overlooked the potential role of incoherence in nonlinear interactions. In this work, we study the synthesis of optical spatial coherence in second harmonic generation using quadratic nonlinear photonic crystals. We demonstrate a method where the second harmonic coherence is customized by employing quantitative phase retrieval and a complex square-root filter sequentially on fundamental frequency speckles. As a proof-of-concept, we experimentally show incoherent imaging of a smiley face transitioning from infrared to visible light. Moreover, we apply this method to produce two representative types of structured light beams in second harmonic generation: incoherent vortex and Airy beams. During the nonlinear synthesis of incoherent vortex beams, we have, for the first time, experimentally verified the conservation of orbital angular momentum in the nonlinear frequency conversion process of a low-coherence source. Furthermore, the generated second-harmonic incoherent Airy beam preserves the self-acceleration characteristics of its fundamental frequency counterpart, remaining unaffected by reductions in coherence. Our results not only deepen the fundamental understanding of optical coherence but also unlock exciting possibilities for applications in infrared imaging and fluorescence microscopy where optical nonlinear interactions play an important role.","PeriodicalId":18069,"journal":{"name":"Light-Science & Applications","volume":"29 4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143495573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Next generation drug clearance insights: real-time tracking in hepatobiliary and renal systems 新一代药物清除洞察：实时跟踪肝胆和肾脏系统

Light-Science & Applications Pub Date : 2025-02-26 DOI: 10.1038/s41377-025-01782-5

Won Hur, Gi Hun Seong, Hak Soo Choi

引用次数: 0