Journal of musculoskeletal & neuronal interactions最新文献_第3页

Trends in Physical Fitness in Children and Adolescents Within the Past 18 Years (DONALD Study). 过去18年儿童和青少年身体健康趋势（DONALD研究）

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Kim Ramona Wloka, Ute Alexy, Nina Reinhart, Evelyn Alberg, Kyriakos Martakis, Eckhard Schoenau, Ibrahim Duran

{"title":"Trends in Physical Fitness in Children and Adolescents Within the Past 18 Years (DONALD Study).","authors":"Kim Ramona Wloka, Ute Alexy, Nina Reinhart, Evelyn Alberg, Kyriakos Martakis, Eckhard Schoenau, Ibrahim Duran","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To evaluate the trends in physical fitness in children and adolescents.Method: The present study focusses on a longitudinal analysis of the single two-legged jump (S2LJ) from children and adolescents, who participated in the DONALD study from 2004 till 2022. P max/body mass (power, surrogate for muscular performance), V max (bounce speed, surrogate for coordination), F max/body mass (force, surrogate for muscular strength) and <math> <mfrac><msub><mi>V</mi> <mi>max</mi></msub> <mrow><msub><mi>F</mi> <mi>max</mi></msub> <mo>/</mo> <mi>BM</mi></mrow> </mfrac> </math> (Nerve-Muscle Index, surrogate for jump efficiency) were examined by linear mixed models and propensity-score(PS)-matching analysis.Results: Data from 1,485 measurements from males and 1,445 from females were included. Mean age was 10.9 years for males and 11.4 years for females. The range of the number of repeated S2LJ was 1 to 8, the median was 3. In PS-matching analysis, there was a dose-effect relationship between the test date and the S2LJ parameters in such a way that P max/body mass and F max/body mass decreased with more recent test dates (effect size at a difference in the test date of 1.7 decades: 0.25 - 0.3) whereby V max and <math> <mfrac><msub><mi>V</mi> <mi>max</mi></msub> <mrow><msub><mi>F</mi> <mi>max</mi></msub> <mo>/</mo> <mi>BM</mi></mrow> </mfrac> </math> showed no consistent trend.Conclusion: Motor performance in children, assessed by the S2LJ, has decreased over the last two decades, mainly due to lower muscular strength, while motor efficiency and coordination seemed to be unchanged.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"336-342"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative Evaluation of Osteoporosis Clinical Risk Assessment Tools in Postmenopausal Women Aged 50-64. 50-64岁绝经后妇女骨质疏松临床风险评估工具的比较评价

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Konstantinos Chlapoutakis, Christos Baltas, Antonios Galanos, Maria Froudaki, Alexia Balanika

{"title":"Comparative Evaluation of Osteoporosis Clinical Risk Assessment Tools in Postmenopausal Women Aged 50-64.","authors":"Konstantinos Chlapoutakis, Christos Baltas, Antonios Galanos, Maria Froudaki, Alexia Balanika","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To assess the performance of five osteoporosis clinical risk assessment tools (SCORE, ORAI, ABONE, OST and OSIRIS), in a subgroup of young postmenopausal women aged 50-64, who underwent DXA screening.Methods: The above-mentioned osteoporosis risk assessment tools were calculated for 258 young postmenopausal women (aged 50-64) who had a DXA scan, in Crete/Greece.Results: Patients with a T-score ≤ -2.5 or a T-score ≤ -2.0 had a statistically significant higher value of SCORE, ORAI and ABONE and a lower value of OST, OSIRIS, and OSIRIS Adjusted Score, compared to the patients with T-score > -2.5 and T-score > -2.0, respectively. ORAI (T-score≤ -2.0) and OST (T-score≤ -2.5) demonstrated the highest sum of sensitivity and specificity. CHAID analysis further confirmed the relative significance of the OST tool in the osteoporosis group (T-score≤ -2.5 vs. T-score > -2.5), for a cut-off of 2.8. In the other group (T-score ≤ -2.0 vs T-score > -2.0) the ORAI score showed a significantly important relationship for a cut-off of 8.Conclusion: OST, despite its performance limitations, correlates best with the DXA measurements of young (50-64), postmenopausal osteoporotic women, a fact which may suggest its' potential role as a screening tool in this specific age group.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"377-384"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Maohuoside A on AMPK Activation in Rats with Osteoarthritis Induced by Anterior Cruciate Ligament Transection. 毛藿香苷A对前交叉韧带断裂所致骨关节炎大鼠AMPK活化的影响。

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Hongwei Wang

{"title":"Effects of Maohuoside A on AMPK Activation in Rats with Osteoarthritis Induced by Anterior Cruciate Ligament Transection.","authors":"Hongwei Wang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To explore the therapeutic effects of Maohuoside A (MHA) on rats with osteoarthritis (OA) induced by anterior cruciate ligament transection, and to analyze its impact on the activation of adenosine monophosphate-activated protein kinase (AMPK).Methods: Sprague-Dawley male rats were divided into six groups: Sham, OA, L-MHA, M-MHA, H-MHA, and H-MHA + Compound C (n = 12 per group). The Sham group had sham surgery, while the OA, L-MHA, M-MHA, and H-MHA groups underwent OA via ACL severing. L-MHA, M-MHA, and H-MHA groups received low, moderate, and high doses of Maohuoside A, respectively, and the H-MHA + Compound C group received high-dose Maohuoside A plus Compound C. Hematoxylin-eosin (HE) staining and Safranin O/Fast Green staining were used to assess articular cartilage damage and degeneration, and the OARSI score was used to evaluate the extent of cartilage degeneration.Results: Compared with the OA group, the L-MHA, M-MHA, and H-MHA groups showed decreased OARSI scores, increased relative levels of Bcl-2 mRNA, decreased relative levels of Bax mRNA, reduced serum levels of IL-1β, IL-6, and TNF-α, increased relative levels of Collagen II mRNA, decreased relative levels of MMP-13 mRNA, and increased relative levels of BMP2, Runx2, and Osterix mRNA. Additionally, the relative level of cartilage AMPKα (Thr172) phosphorylation increased (P<0.05).Conclusion: This study suggests that Maohuoside A exerts anti-osteoarthritis (OA) effects by activating AMPK.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"400-408"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609567/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to the Commentary on: "The Diagnostic Role of Adding the Hoffman Reflex for L5 Radiculopathy in the Electrodiagnostic Laboratory: A Cross-sectional Study". 对“在电诊断实验室中加入Hoffman反射对L5神经根病的诊断作用：一项横断面研究”评论的回应。

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Hasan Kara, Elif Balevi Batur, Abdulvahap Kahveci, Onur Karacif, Önder Murat Özerbil, İlknur Albayrak Gezer, Funda Levendoğlu, Murat Zinnuroğlu

引用次数: 0

CYR61 as a Potential Apoptosis Biomarker in Osteoarthritis with Comorbidities. CYR61作为骨关节炎合并症的潜在凋亡生物标志物

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Murat Tokus, Hakan Cicek, Hüseyin Ates, Cagil Coskun, Yusuf Dogus, Figen Cicek

{"title":"CYR61 as a Potential Apoptosis Biomarker in Osteoarthritis with Comorbidities.","authors":"Murat Tokus, Hakan Cicek, Hüseyin Ates, Cagil Coskun, Yusuf Dogus, Figen Cicek","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Obesity and diabetes mellitus (DM) are major risk factors for osteoarthritis (OA), but it remains unclear how comorbidity affects apoptosis signaling in OA. This study investigated the effect of metabolic diseases on apoptosis and apoptosis-related intracellular and extracellular signaling in OA.Methods: Excision materials of human articular cartilage from total knee arthroplasties were collected. The samples were divided into four groups as, control OA, OA+DM, OA+Obese, and OA+DM+obesity. Protein activities were determined using Western blot and ELISA.Results: Caspase-3 levels were significantly increased in chondrocytes in which OA was associated with DM or obesity. However, an increase in Bcl-2 activity was also observed in these comorbidities. The increased levels of CaMKII in the same groups also indicate an increase in cellular activity in comorbidities. While IL-6 and TNF-α did not show significant changes, matrix regulatory protein CYR61 levels reflected the intracellular apoptotic activity.Conclusion: Metabolic diseases have a stimulatory effect on the etiopathology of osteoarthritis by enhancing cellular signaling towards apoptosis and that matrix signaling proteins may play a key role in regulating these effects. Examining OA with its accompanying diseases will lead to a better understanding of the cellular mechanisms that differ in OA.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"385-393"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609561/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Which Bone-Modifying Agents Are Most Effective in Reducing Bone Loss in Women with Early and Locally Advanced Breast Cancer? - A Cochrane Review summary with commentary. 哪种骨修饰剂对减少早期和局部晚期乳腺癌患者骨质流失最有效？- Cochrane综述摘要及评论。

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Ekin Ilke Sen

引用次数: 0

Intra and Inter-Session Reliability of Movement Velocity During Pull-Ups Performed at Small Climbing Holds. 小攀点引体向上运动过程中运动速度的内部和内部可靠性。

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Cesar Sordo-Vacas, Amador Garcia-Ramos, David Colomer-Poveda

{"title":"Intra and Inter-Session Reliability of Movement Velocity During Pull-Ups Performed at Small Climbing Holds.","authors":"Cesar Sordo-Vacas, Amador Garcia-Ramos, David Colomer-Poveda","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: The synergy between arm and shoulder muscles, along with isometric finger flexor strength, are crucial for climbing proficiency. However, tests often assess these factors separately rather than in a unified action. This study aimed to determine the intra- and inter-session reliability of the mean propulsive velocity (MPV) during pull-ups on a large hold and on small climbing edges.Methods: Ten male climbers (self-reported maximal grade 6b-8b on French scale) participated in two identical sessions. During each session, participants performed two blocks of two pull-ups on a large hold and on four small climbing edges (25, 20, 15, and 10mm) in randomized order. The MPV was recorded using a linear position transducer.Results: The MPV during climbing pull-ups at 20mm (0.75±0.16 m/s), 15mm (0.73±0.16 m/s), and 10mm (0.52±0.15 m/s) was reduced compared to a pull-up on a large hold (0.84±0.16m/s). Intraclass correlation coefficients (ICCs) were good-to-excellent across hold sizes for intra-session (ICC 0.84-0.99) and inter-session (ICC 0.73-0.96) measurements.Conclusions: The results suggest that the MPV assessed during climbing-specific pull-ups on small holds provides valuable insights into finger, elbow and shoulder muscle force capacities in a unified action. This test could be considered a sport-specific test for monitoring performance in climbers.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"370-376"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609558/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ischemic Preconditioning Improves Hip Abductor Strength and Power in Patients with Symptomatic Knee Osteoarthritis. 缺血性预适应改善症状性膝骨关节炎患者髋关节外展肌的力量和力量。

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Shraddha Sudhir, Kharma C Foucher, Pim Jetanalin, Lindsay Slater Hannigan

{"title":"Ischemic Preconditioning Improves Hip Abductor Strength and Power in Patients with Symptomatic Knee Osteoarthritis.","authors":"Shraddha Sudhir, Kharma C Foucher, Pim Jetanalin, Lindsay Slater Hannigan","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To investigate the effect of ischemic preconditioning (IC) on bilateral hip abductor strength, fatigue, and power in patients with knee osteoarthritis (KOA).Methods: Participants (n=10) with KOA completed isokinetic and isometric hip abductor assessments on a Biodex dynamometer both before and after IC. IC was administered during a single session and consisted of 5 minutes of inflation (225mmHg) followed by 5 minutes of reperfusion for 50 minutes. Changes in strength and endurance measures before and after IC were compared using paired t-tests and magnitude of significant differences were reported using Cohen's d effect sizes.Results: Isokinetic hip abductor peak torque (d=.42, p=.027) and average power (d=.57, p=.029) in the involved limb, and isokinetic peak torque (d=.37, p=.044) in the uninvolved limb increased significantly after IC compared to baseline. There were no changes in isokinetic average power in the uninvolved limb, or isometric peak torque and fatigue index in both limbs after IC (p=.13-.77).Conclusions: A single session of IC improved hip abductor strength in both limbs and power in the involved limb in KOA patients. IC should continue to be investigated as a safe and clinically convenient intervention that can supplement traditional modalities to improve muscle function in KOA.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"353-360"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609566/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bridging Dynamic Neuromuscular Stabilization Synergism with Movement Control Impairment Related Non-Specific Low Back Pain: Scoping Review. 桥接动态神经肌肉稳定协同作用与运动控制障碍相关的非特异性腰痛：范围审查。

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Manju Kaushik, Irshad Ahmad

{"title":"Bridging Dynamic Neuromuscular Stabilization Synergism with Movement Control Impairment Related Non-Specific Low Back Pain: Scoping Review.","authors":"Manju Kaushik, Irshad Ahmad","doi":"","DOIUrl":"","url":null,"abstract":"Non-specific chronic low back pain (NSCLBP) with movement control impairment (MCI) subgroup often experiences postural pain and functional lumbar spine instability. This scoping review had two aims: 1) to map the evidence related to dynamic neuromuscular stabilization (DNS) efficacy as a spinal stabilization strategy and to identify gaps in the literature that may exist regarding the effectiveness of DNS in low back pain management and 2) to align the DNS approach as a potential intervention for MCI patients. The clinical trial studies related to DNS exercises were searched from inception until February 2024 through electronic databases, such as PubMed, Google Scholar, PEDro, and Science Direct. The Arksey and O'Malley methodology and PRISMA-ScR checklist were followed to report the findings. A total of 18 studies offering a total sample of 483, were included based on the inclusion criteria. The results of 14 studies summarized the DNS-related influence on neural substrates and core stability. The availability of only 4 studies on DNS efficacy in chronic low back pain indicates a dearth of evidence. This review highlighted the DNS efficacy in improving core muscle activation and pain-related symptoms in NSCLBP patients while emphasising the need for prospective research in the MCI subgroup.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"420-432"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory Muscle Strength Correlation with Functional Capacity, Quality of Life, Demographics and Co-morbidities in Stroke and Spinal Cord Injury. 呼吸肌肉力量与脑卒中和脊髓损伤的功能能力、生活质量、人口统计学和合并症的相关性。

IF 1.7 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2024-12-01

Sofia Ferfeli, Antonios Galanos, Ismene A Dontas, Dimitrios Pitidis-Poutous, Ioannis K Triantafyllopoulos, Zaira Symeonidou, Damiani Tsiamasfirou, Efstathios Chronopoulos

{"title":"Respiratory Muscle Strength Correlation with Functional Capacity, Quality of Life, Demographics and Co-morbidities in Stroke and Spinal Cord Injury.","authors":"Sofia Ferfeli, Antonios Galanos, Ismene A Dontas, Dimitrios Pitidis-Poutous, Ioannis K Triantafyllopoulos, Zaira Symeonidou, Damiani Tsiamasfirou, Efstathios Chronopoulos","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To record Maximal Inspiratory Pressure (MIP) and Maximal Expiratory Pressure (MEP) in neuro-rehabilitation patients and establish correlation with functional status, quality of life, demographics and co-morbidities.Methods: Respiratory muscle strength was measured in 50 stroke patients and 50 spinal cord injury (SCI) patients. Both groups were evaluated with the Modified Barthel Index (MBI-Shah version) and the 36-Item Short Form Survey. Demographics, medical history, history of moderate physical activity prior to injury and American Spinal Injury Association (ASIA) classification were recorded.Results: Respiratory muscle strength declined with age and males exhibited higher MIP and MEP in the SCI group and higher MEP, but not MIP, in stroke. In the ASIA D SCI subgroup, the MBI total score was moderately positively correlated with MIP and MEP values. In stroke, MBI total score and MEP were positively correlated in both sexes and MBI total score and MIP in females. Diabetes mellitus absence correlated with higher MIP and MEP in SCI. Prior physical activity was linked to higher MIP, MEP in stroke and to higher MIP in SCI.Conclusions: Age, sex, functional capacity, SCI classification, quality of life components, history of physical activity and diabetes influence respiratory muscle strength in the studied population.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"24 4","pages":"361-369"},"PeriodicalIF":1.7,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11609559/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0