Journal of musculoskeletal & neuronal interactions最新文献

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The Effect of Kinesio Taping Applied to Quadriceps and Gastrocnemius Muscles on Speed, Agility and Flexibility: A Cross-Sectional Study. 股四头肌和腓肠肌肌内效贴布对速度、敏捷性和灵活性的影响:一项横断面研究。
IF 1.9 4区 医学
Tolga Hanayoğlu, Sema Can
{"title":"The Effect of Kinesio Taping Applied to Quadriceps and Gastrocnemius Muscles on Speed, Agility and Flexibility: A Cross-Sectional Study.","authors":"Tolga Hanayoğlu, Sema Can","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to examine the effect of kinesio tape (KT) applied to different parts of the body on speed, agility and flexibility.</p><p><strong>Method: </strong>32 male volunteers aged 18-38 years participated in the study. KT was applied to the quadriceps and gastrocnemius muscles of the athletes at 4 different times with intervals of one week. As measurements, 30-meter sprint test, agility T test and sit and reach test for flexibility were performed. Independent samples T-Test and Mann Whitney U test, repeated measures analysis of variance and the Friedman test were used for statistical analysis.</p><p><strong>Results: </strong>No significant difference was found between the speed, agility and flexibility values of KT applied to quadriceps and gastrocnemius muscles (p>0.05). It was found that there was an increase in agility performance in both muscle groups in the 48<sup>th</sup> hour measurements after the KT application, it increased speed performance only in gastrocnemius muscle (p<0.05) and did not increase flexibility performance in both muscle groups. There was no statistically significant improvement in the 30<sup>th</sup> minute and 24<sup>th</sup> hour measurements (p>0.05).</p><p><strong>Conclusion: </strong>It can be suggested that applying KT to quadriceps and gastrocnemius muscles with 25-50% tension for 48 hours is effective in improving the agility performance.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 4","pages":"417-425"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696375/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460467","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of Bushen Tiansui Decoction on Delayed Fracture Healing: A Systematic Review and Meta-analysis. 补肾天遂汤对骨折延迟愈合的影响:系统回顾和meta分析。
IF 1.9 4区 医学
Ling Cheng, Gao Wang, Hualong Lu, Song Li, Wei Xiong, Jun Wang
{"title":"Effect of Bushen Tiansui Decoction on Delayed Fracture Healing: A Systematic Review and Meta-analysis.","authors":"Ling Cheng, Gao Wang, Hualong Lu, Song Li, Wei Xiong, Jun Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This review aimed to validate the therapeutic potential of Bushen Tiansui decoction (BSTSD), a traditional Chinese formulation, in treating delayed union of fractures. Comprehensive database searches identified randomized controlled trials up to September 13, 2022, assessing BSTSD's efficacy in delayed fracture healing. Outcomes were bone metabolism indexes and Harris hip scores. Quality and risk assessments were conducted using the Cochrane Collaboration's tools. Data were analyzed using RevMan software, with sensitivity analysis through Stata. BSTSD significantly improved bone GLA protein (SMD=1.76, P<0.00001) and alkaline phosphatase (SMD=1.31, P<0.00001). Additionally, Harris hip scores for pain, function, deformity, and motion showed marked improvement. BSTSD treatment also demonstrated enhanced clinical efficiency (RR=1.27, P<0.00001) with fewer complications. Sensitivity analyses indicated consistent results. BSTSD shows promise in treating delayed fracture unions, yet conclusions necessitate further high-quality research for validation.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 4","pages":"471-488"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Study on the Effect of Precise Rehabilitation Therapy Guided by Three-dimensional-computed Tomography Reconstruction Technology in Hip Fracture Surgery Patients. 三维计算机断层扫描重建技术指导下精准康复治疗在髋部骨折患者中的效果研究。
IF 1.9 4区 医学
Zhongwei Yan, Jia Jiang, Wencai Sun, Jinhua Zhang, Jinhui Qi, Yanjun Qiu, Ping Du
{"title":"A Study on the Effect of Precise Rehabilitation Therapy Guided by Three-dimensional-computed Tomography Reconstruction Technology in Hip Fracture Surgery Patients.","authors":"Zhongwei Yan, Jia Jiang, Wencai Sun, Jinhua Zhang, Jinhui Qi, Yanjun Qiu, Ping Du","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate the effectiveness of precise rehabilitation therapy guided by three-dimensional computed tomography (3D-CT) reconstruction technology in hip fracture patients through a retrospective cohort study.</p><p><strong>Method: </strong>Data were retrospectively collected from 60 patients aged over 60 who had undergone hip fracture surgery. They were divided into two groups based on their chosen rehabilitation method: a control group and a test group. The study collected demographic data, fracture characteristics, and quality of life indicators to assess the impact of rehabilitation on economic indicators and daily living activities (ADL). Additionally, it included assessments of muscle strength, joint mobility, hip function, postoperative complications, and records of hospitalization information and costs. Cognitive function was also assessed postoperatively.</p><p><strong>Results: </strong>There were no significant differences in demographic data, fracture characteristics, ADL, or Fugl-Meyer assessment (FMA) between the two groups. However, the test group exhibited significantly higher post-surgery muscle strength recovery and hip mobility compared to the control group (P<0.05). Additionally, the test group had significantly fewer hospitalization days and lower hospitalization costs than the control group (P<0.05).</p><p><strong>Conclusion: </strong>Precise rehabilitation therapy guided by 3D-CT reconstruction technology for hip fracture surgery patients can enhance early muscle strength recovery, improve mobility of the affected limb, reduce hospitalization duration and costs, and enhance overall patient recovery outcomes.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 4","pages":"506-516"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696373/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Application of 3D Printing Navigation Template Technology in Severe Hallux Valgus Surgery. 3D打印导航模板技术在严重外翻手术中的应用。
IF 1.9 4区 医学
Tinghu Zhao, Hanxin Chen, Bin Jia, Yong Zhang, Yuxia Wang, Yunbo Bai
{"title":"Application of 3D Printing Navigation Template Technology in Severe Hallux Valgus Surgery.","authors":"Tinghu Zhao, Hanxin Chen, Bin Jia, Yong Zhang, Yuxia Wang, Yunbo Bai","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To explore the application of 3D printed navigation template technology in severe Hallux valgus surgery.</p><p><strong>Methods: </strong>Forty-eight patients with severe Hallux valgus were selected. There were 24 cases in the control group underwent hallux valgus osteotomy using traditional methods and fixed with fully threaded hollow screws during the surgery. There were 24 cases in the 3D group who underwent personalized osteotomy using 3D printing navigation template technology. Patients were followed up regularly for six months after surgery.</p><p><strong>Results: </strong>The surgery time of the 3D group was shorter than that of the control group, and the intraoperative bleeding was reduced (P<0.05). Compared with the preoperative data, the HVA and IMA significantly reduced immediately and 1, 3, and 6 months after surgery (P<0.05). The VAS scores decreased significantly, while the AOFAS and SF-36 scores increased (P<0.05). At three months and six months after surgery, the VAS score of the 3D group was lower than that of the control group, while the SF-36 score was higher (P<0.05). During the follow-up period, both groups had no recurrent cases or complications.</p><p><strong>Conclusions: </strong>The 3D printing navigation template technology improves patients' prognosis, functional recovery, and quality of life.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 4","pages":"448-455"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696366/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460458","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of Multi-joint Eccentric Training on Muscle Function When Combined With Aquatic Plyometric Training: A Minimal Dose, Mixed Training Study. 多关节偏心训练与水中增强训练相结合对肌肉功能的影响:一项小剂量混合训练研究。
IF 1.9 4区 医学
Cassidy Weeks, Brennan J Thompson, Steven B Spencer, Cody Fisher, Dianne Althouse, Talin J Louder, Eadric Bressel
{"title":"Effects of Multi-joint Eccentric Training on Muscle Function When Combined With Aquatic Plyometric Training: A Minimal Dose, Mixed Training Study.","authors":"Cassidy Weeks, Brennan J Thompson, Steven B Spencer, Cody Fisher, Dianne Althouse, Talin J Louder, Eadric Bressel","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the effects of a combined eccentric overload and aquatic-based plyometric training program on muscle function/performance measures and soreness versus an eccentric-only training protocol using a minimal dose training paradigm.</p><p><strong>Methods: </strong>Twenty-five participants were randomized into either an eccentric-only training group (ECC) or a combined eccentric and aquatic plyometric group (ECC + AQP). The ECC group performed eccentric training once per week for 6-weeks while the ECC + AQP group performed the same eccentric training but with an additional aquatic plyometric training session.</p><p><strong>Results: </strong>There was no group × trial interactions for any of the variables. However, the training elicited large improvements in eccentric strength in both ECC (27%; ES = 1.33) and ECC+AQP (17%; ES = .86) groups. Isometric strength improved moderately for ECC and ECC+AQP groups (17.2%, ES = .53;9%, ES = .45). A moderate increase was observed for depth jump height for both ECC and ECC+AQP groups (13.1%, ES = .48;8.8%, ES = .36). No changes were observed for countermovement jump or sprint time and muscle soreness did not differ between groups.</p><p><strong>Conclusions: </strong>Minimal dose multi-joint eccentric overload training improved strength and depth jump outcomes after 6-weeks regardless of the training condition but adding a minimal dose aquatic plyometric protocol does not improve muscle function-based outcomes.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 4","pages":"386-396"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevention of bone deterioration by whole-body vibration in a rat model of pre-type 2 diabetes. 2型糖尿病前期大鼠全身振动对骨质退化的预防作用
IF 1.9 4区 医学
Akira Minematsu, Yasue Nishii
{"title":"Prevention of bone deterioration by whole-body vibration in a rat model of pre-type 2 diabetes.","authors":"Akira Minematsu, Yasue Nishii","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To examine effects of whole-body vibration (WBV) on bone properties in pre-type 2 diabetes mellitus (T2DM) rats.</p><p><strong>Methods: </strong>Six-week-old male Hos:ZFDM-<i>Lepr <sup>fa</sup></i>, <i>fa/fa</i> (DM) and Hos:ZFDM-<i>Lepr<sup>fa</sup>,fa/+</i> (CON; untreated non-DM) rats were used in the experiments. Half of DM rats were subjected to WBV (45 Hz, 0.5 g, 15 min/day, 5 days/week) for 8 weeks (WBV group), and the other half was not (DM group).</p><p><strong>Results: </strong>Bone mass, trabecular bone microstructure (TBMS), and cortical bone geometry (CBG) parameters were worse in the DM and WBV groups compared with the CON group. Maximum load was significantly decreased in the DM group compared with the CON group, and the break point was significantly higher in the WBV group compared with the DM group. Serum levels of bone specific alkaline phosphatase were significantly lower in the WBV group compared with the CON group. Glycemic control was not worse in the WBV group compared with the DM group, but not the same levels as the CON group.</p><p><strong>Conclusions: </strong>These findings suggest that WBV can potentially delay the decrease in maximum load, although it does not prevent the deterioration of bone mass, TBMS, and CBG parameters.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 4","pages":"426-435"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696377/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transcranial Direct Current Stimulation Attenuates the Chronic Pain of Osteoarthritis in Rats via Reducing NMDAR2B Expressions in the Spinal Cord. 经颅直流电刺激通过降低脊髓NMDAR2B表达减轻骨关节炎大鼠慢性疼痛。
IF 1.9 4区 医学
Zhihua Liu, Xia Chen, Peng Chen, Lili Wang
{"title":"Transcranial Direct Current Stimulation Attenuates the Chronic Pain of Osteoarthritis in Rats via Reducing NMDAR2B Expressions in the Spinal Cord.","authors":"Zhihua Liu, Xia Chen, Peng Chen, Lili Wang","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>Osteoarthritis (OA) has been the common cause to lead to chronic pain. Transcranial direct current stimulation (tDCS) is effective in the treatment of chronic pain, but its analgesic mechanism is still unclear. This study observed the analgesic effects of tDCS in rats to explore the top-down analgesic modulation mechanism of tDCS.</p><p><strong>Methods: </strong>Monosodium iodoacetate (MIA) was used to establish OA chronic pain model. After 21 days, the rats received tDCS for 14 consecutive days (20 min/day). We assessed the pain-related behaviors of rats at different time points. Western blot and Immunohistochemistry were performed to observe the expression level of NMDAR2B in the spinal cord after tDCS treatment.</p><p><strong>Results: </strong>After MIA injection, rats developed apparent mechanical hyperalgesia and thermal hyperalgesia. However, the pain-related behaviors of rats were significantly improved after tDCS treatment. In addition, the expression of NMDAR2B and the proportion of positive stained cells of NMDAR2B were reversed by tDCS treatment.</p><p><strong>Conclusions: </strong>The results demonstrated that tDCS can attenuate OA-induced chronic pain in rats via reducing NMDAR2B expressions in the spinal cord. We believe that this may be the result of tDCS participating in the top-down modulation of pain pathway in the endogenous analgesic system.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 4","pages":"498-505"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10696371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138460468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Performance Fatigability and Neuromuscular Responses Are Not Joint Angle Specific Following a Sustained Isometric Forearm Flexion Task Anchored to a High Perceptual Intensity in Women. 表现疲劳和神经肌肉反应不是关节角度特定后,一个持续的等长前臂屈曲任务锚定在高知觉强度。
IF 1.9 4区 医学
Jocelyn E Arnett, Robert W Smith, Tyler J Neltner, John Paul V Anders, Dolores G Ortega, Terry J Housh, Richard J Schmidt, Glen O Johnson
{"title":"Performance Fatigability and Neuromuscular Responses Are Not Joint Angle Specific Following a Sustained Isometric Forearm Flexion Task Anchored to a High Perceptual Intensity in Women.","authors":"Jocelyn E Arnett,&nbsp;Robert W Smith,&nbsp;Tyler J Neltner,&nbsp;John Paul V Anders,&nbsp;Dolores G Ortega,&nbsp;Terry J Housh,&nbsp;Richard J Schmidt,&nbsp;Glen O Johnson","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the effects of joint angle (JA) on maximal voluntary isometric contractions (MVIC) and neuromuscular responses following a sustained, isometric forearm flexion task anchored to a rating of perceived exertion (RPE) of 8 (RPE=8).</p><p><strong>Methods: </strong>Nine women (age: 20.7±2.9 yrs; height: 168.8±7.2 cm; body mass: 66.3±6.8 kg) performed 2,3s forearm flexion MVICs at JAs of 75°, 100°, and 125° prior to and following a sustained, isometric forearm flexion task anchored to RPE=8 to task failure (torque reduced to zero) at JA100. Electromyographic (EMG) and mechanomyographic (MMG) signals were recorded from the biceps brachii.</p><p><strong>Results: </strong>The MVIC at JA100 (collapsed across Time) was significantly greater (p<0.05) than JA75 and JA125. The pre-test MVIC was significantly greater (p<0.001) than the post-test. For EMG amplitude (AMP) and EMG mean power frequency (MPF), pre-test values were significantly greater (p<0.05) than the post-test values, with no differences between JAs. For MMG AMP and MMG MPF, there were no significant (p>0.05) differences between Time or JAs. Pre-test neuromuscular efficiency (normalized MVIC/normalized EMG AMP) was significantly greater (p=0.005) than post-test.</p><p><strong>Conclusion: </strong>Following a sustained, isometric forearm flexion task anchored to RPE=8 at JA100, the fatigue-induced MVIC and neuromuscular responses were not affected by JA.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 3","pages":"299-307"},"PeriodicalIF":1.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/b2/JMNI-23-299.PMC10483820.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10187268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral Fatigue Fractures of the Femur. 双侧股骨疲劳骨折。
IF 1.9 4区 医学
Christos Koutserimpas, Maria Piagkou, Efstathios Chronopoulos, Konstantinos Raptis, Dimitrios Kotzias, Symeon Naoum, Nikolaos-Achilleas Arkoudis
{"title":"Bilateral Fatigue Fractures of the Femur.","authors":"Christos Koutserimpas,&nbsp;Maria Piagkou,&nbsp;Efstathios Chronopoulos,&nbsp;Konstantinos Raptis,&nbsp;Dimitrios Kotzias,&nbsp;Symeon Naoum,&nbsp;Nikolaos-Achilleas Arkoudis","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 3","pages":"368-370"},"PeriodicalIF":1.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ad/a1/JMNI-23-368.PMC10483815.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10197740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrasonographic Evaluation of the Distal Femoral Cartilage Thickness in Parkinson's Patients. 帕金森病患者股骨远端软骨厚度的超声评价。
IF 1.9 4区 医学
Alper Uysal, Murat Guntel, Özcan Demetgül, Ulaş Çiçek
{"title":"Ultrasonographic Evaluation of the Distal Femoral Cartilage Thickness in Parkinson's Patients.","authors":"Alper Uysal,&nbsp;Murat Guntel,&nbsp;Özcan Demetgül,&nbsp;Ulaş Çiçek","doi":"","DOIUrl":"","url":null,"abstract":"<p><strong>Objectives: </strong>Both Parkinson's disease (PD) and osteoarthritis (OA) are characterized by chronic inflammation and tissue degeneration. The aim of this study is to investigate the relationship between PD and distal femoral cartilage thickness (DFCT). Our study is the first in the literature to measure DFCT in PD.</p><p><strong>Methods: </strong>68 patients with PD and 30 healthy individuals participated. The patient group was divided into three subgroups, according to the Hoehn Yahr stages (HYS): mild, moderate and severe. Patient subgroups and the control group were compared with each other in terms of neutrophil-lymphocyte ratio (NLR), C-reactive protein (CRP), and DFCT.</p><p><strong>Results: </strong>The NLR and CRP levels of the PD patients were higher than the values of the healthy people. The DFCT values of the mild PD subgroup were significantly higher than those of the control group, except for one value. The DFCT values of the moderate PD subgroup and the healthy group were similar. The DFCT values of the severe PD subgroup were lower than the values of the healthy group.</p><p><strong>Conclusions: </strong>Our study showed the presence of ultrasonographic evidence consistent with early signs of cartilage destruction in early-stage PD disease. As the PD stage progressed, the cartilage thickness decreased accordingly.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"23 3","pages":"328-337"},"PeriodicalIF":1.9,"publicationDate":"2023-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b5/99/JMNI-23-328.PMC10483812.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10194505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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