Journal of musculoskeletal & neuronal interactions最新文献

The Diagnostic Value of Musculoskeletal Ultrasound in Knee Osteoarthritis and Its Correlation with Pain Stratification. 肌肉骨骼超声对膝关节骨性关节炎的诊断价值及其与疼痛分层的关系。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Wenfang Cui, Fuwang Zhang

{"title":"The Diagnostic Value of Musculoskeletal Ultrasound in Knee Osteoarthritis and Its Correlation with Pain Stratification.","authors":"Wenfang Cui, Fuwang Zhang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This study aimed to evaluate the diagnostic value of musculoskeletal ultrasound in patients with knee osteoarthritis (KOA) and to assess its correlation with pain stratification, with the goal of supporting early diagnosis and personalized pain management in KOA.Methods: A total of 128 patients with KOA were retrospectively selected. Based on their visual analogue scale (VAS) scores, the patients were categorized into mild, moderate, and severe KOA groups. Line charts and histograms were used to illustrate the distribution and variation of pain levels and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) scores. Scatter plots were generated to analyze the correlation between musculoskeletal ultrasound findings and pain scores.Results: Preliminary analysis revealed a significant correlation between ultrasound findings and both VAS and WOMAC scores (P < 0.05). Line charts demonstrated an upward trend in VAS scores with increasing pain severity. Histograms indicated significant differences in the distribution of WOMAC scores across different pain stratification levels.Conclusion: Musculoskeletal ultrasound demonstrates strong diagnostic value in KOA and shows a significant correlation with pain stratification. This non-invasive imaging modality may serve as an effective clinical tool for individualized pain assessment and informed treatment planning.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"283-288"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In Vivo and In Vitro Analysis of Cathepsin D in Bone Homeostasis and Osteoporosis. 组织蛋白酶D在骨稳态和骨质疏松症中的体内外分析。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Song Yan, Jiancong Zeng, Wei Dong, Jinsong Wei

{"title":"In Vivo and In Vitro Analysis of Cathepsin D in Bone Homeostasis and Osteoporosis.","authors":"Song Yan, Jiancong Zeng, Wei Dong, Jinsong Wei","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To explore the role of cathepsin D (CTSD), a lysosomal aspartyl protease, as a potential biomarker and therapeutic target in the context of osteoporosis.Methods: Utilizing single-cell sequencing data from the Gene Expression Omnibus (GEO) database, we identified differential expression patterns of CTSD in human femoral head tissues between osteoporotic and non-osteoporotic states. Human mesenchymal stem cells (MSCs) were treated with recombinant human CTSD and/or osteogenic induction medium and the role of CTSD on osteoblast differentiation were investigated by RT-qPCR, western blot, immunofluorescence staining and alizarin red staining. The role of CTSD on osteoporotic changes was further verified in ovariectomized mice.Results: In vitro analyses of human mesenchymal stem cells (MSCs) treated with recombinant human CTSD (rhCTSD) under osteogenic induction conditions revealed modulation of osteogenic marker expression, including ALP, COL1A1, and RUNX2. Histological assessments using Alizarin Red staining and immunofluorescence corroborated these findings, demonstrating that CTSD influences osteoblast differentiation and matrix mineralization. In vivo studies in mice further supported the role of CTSD, showing that perturbations in this enzyme result in alterations in bone mineral density and volume characteristic of osteoporotic changes.Conclusion: Collectively, these findings implicate CTSD as a regulator of bone homeostasis and support its potential as a novel target for therapeutic intervention in osteoporosis.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"341-350"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Shoulder Joint Isokinetic Muscle Strength, Endurance and Proprioception on Swimming, Agility and Sprint Performance in Water Polo Players. 肩关节等速肌力、耐力和本体感觉对水球运动员游泳、敏捷性和短跑成绩的影响。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Musa Çankaya, Serdar Büyükipekçi, Ökkaş Keretli

{"title":"The Effect of Shoulder Joint Isokinetic Muscle Strength, Endurance and Proprioception on Swimming, Agility and Sprint Performance in Water Polo Players.","authors":"Musa Çankaya, Serdar Büyükipekçi, Ökkaş Keretli","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: Water Polo (WP) is a physiologically and physically demanding sport that involves frequent directional changes during swimming.Methods: This study, shoulder proprioception, muscle strength, and endurance were evaluated using an isokinetic dynamometer in 28 male Sports Club WP athletes competing in the WP 1st league. In addition, swimming, agility, and speed performance tests were performed.Results: There was a moderate negative correlation between shoulder joint muscle strength and the shuttle swimming test, WP agility test, and 20-m maximum speed swimming test (Peak Torque 60° respectively r:-0.443, p:0.018, r:-0.490, p:0.008, r=-0.581, p:0.001). In the multiple regression analysis performed in our study, ANOVA test results in Models 4, 5, and 6 showed that there was a significant relationship between shoulder joint muscle strength and shuttle swimming test and 20-m maximum speed swimming test (respectively, F:2.912, p:0.044, F:5.004, p:0.005).Conclusions: Our study determined that shoulder joint proprioception was not associated with swimming, agility and speed performance, shoulder joint isokinetic muscle strength affected swimming and speed performance but not agility, and shoulder joint endurance was associated with swimming, agility and speed performance in WP players.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"289-298"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401471/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of Vibration Frequency and Loading on Lower Limb Muscle Activation and Time-Varying Multi-Muscle Coactivation in Whole-Body Vibration Training among Recreational Runners. 振动频率和负荷对休闲跑步者全身振动训练中下肢肌肉激活和时变多肌肉协同激活的影响

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Hyeri Nam, Lulu Yin, Peng Chen, Lin Wang

{"title":"Effects of Vibration Frequency and Loading on Lower Limb Muscle Activation and Time-Varying Multi-Muscle Coactivation in Whole-Body Vibration Training among Recreational Runners.","authors":"Hyeri Nam, Lulu Yin, Peng Chen, Lin Wang","doi":"","DOIUrl":"","url":null,"abstract":"Objective: This study examined the effects of vibration frequency and additional loading on lower limb muscle activation and coactivation during whole-body vibration (WBV) training in recreational runners.Methods: Twenty-five male runners performed WBV training at six frequencies (0-50 Hz) under two loading conditions (no load vs. 20% body mass). Surface electromyography was used to record electromyography root mean square (EMGrms) in 11 lower limb muscles. Coactivation of six muscles was analyzed using the time-varying multi-muscle coactivation function. 1D statistical parametric mapping and two-way repeated-measures ANOVA were used to assess differences.Results: EMGrms was significantly influenced by vibration frequency and loading. Additional loading increased activation in the gluteus maximus, quadriceps, hamstrings, and soleus (p < 0.001). Frequency effects were notable in the gluteus maximus and hamstrings, with 10-30 Hz inducing higher muscular activation than the no-vibration case (p < 0.01). Coactivation was significantly high with loading (p < 0.001), particularly during the eccentric squat phase, but frequency had no significant effect.Conclusion: Additional loading enhances muscle activation and coactivation, and vibration frequency primarily affects muscular activation. These findings highlight the importance of external load and frequency in optimizing WBV training for enhancing sports performance and preventing injuries in runners.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"328-340"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Construction of a lncRNA-miRNA-mRNA Network for Biomarker Identification in Intervertebral Disc Degeneration. 用于椎间盘退变生物标志物鉴定的lncRNA-miRNA-mRNA网络的构建。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Kai Huang, Lingling Shen, Huiqin Guan, Lei Dai, Xiaogang Huang, Xinjun Zhang, Xiaojun Xu, Chao Liu

{"title":"Construction of a lncRNA-miRNA-mRNA Network for Biomarker Identification in Intervertebral Disc Degeneration.","authors":"Kai Huang, Lingling Shen, Huiqin Guan, Lei Dai, Xiaogang Huang, Xinjun Zhang, Xiaojun Xu, Chao Liu","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To identify pivotal gene markers and pathways involved in intervertebral disc degeneration (IDD) through the construction of a competing endogenous RNA (ceRNA) network.Methods: A ceRNA network was constructed using mRNAs associated with clinical IDD phenotypes (age, MRI grade), identified through Weighted Gene Co-expression Network Analysis (WGCNA). From the core mRNAs within the ceRNA network, potential marker genes were identified using LASSO regression, Support Vector Machine (SVM), and Random Forest algorithms. A sub-network was then constructed, and the candidate marker genes were further validated using the mouse IDD dataset GSE134955.Results: A total of 119 differentially expressed long non-coding RNAs (DELs), 1,267 differentially expressed mRNAs (DEMs), and 37 differentially expressed microRNAs (DEMis) were identified in IDD samples compared to controls. WGCNA identified 1,190 DEMs significantly associated with MRI grade. Based on these MRI grade-associated DEMs, a hub ceRNA network comprising 4 DEMis, 90 DELs, and 18 DEMs was established. Among these, three DEMs-BTG2, MDM4, and ACOX1-were consistently identified as marker genes by LASSO, SVM, and Random Forest. These three genes also demonstrated high accuracy in distinguishing IDD from control samples in the independent mouse dataset.Conclusion: This study identified key mRNAs implicated in IDD progression and provides new insights into the regulatory roles of ceRNA networks in the disease. These findings may contribute to the development of novel diagnostic biomarkers and therapeutic targets for IDD.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"316-327"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401473/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957745","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

LASSO Logistic Regression was Used to Analyze the Risk Factors for Cauda Equina Injury Secondary to Lumbar Spinal Stenosis and to Build a Risk Model. 采用LASSO Logistic回归分析马尾损伤继发于腰椎管狭窄症的危险因素，建立风险模型。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Kai Liu, Yue Wu, Pengfei Ma, Can Zheng, Xuefeng Ma, Xinhua Hu, Wenping Lin, Xu He

{"title":"LASSO Logistic Regression was Used to Analyze the Risk Factors for Cauda Equina Injury Secondary to Lumbar Spinal Stenosis and to Build a Risk Model.","authors":"Kai Liu, Yue Wu, Pengfei Ma, Can Zheng, Xuefeng Ma, Xinhua Hu, Wenping Lin, Xu He","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To analyze the risk factors for secondary cauda equina injury in lumbar spinal stenosis using LASSO logistic regression and to construct a risk prediction model in the form of a nomogram.Methods: Patients with lumbar spinal stenosis were divided into a secondary injury group (90 cases) and a non-secondary injury group (110 cases). LASSO logistic regression was applied, and a risk nomogram was generated. The predictive efficacy of the model was evaluated using receiver operating characteristic (ROC) curves and calibration curves.Results: The ROC curve analysis showed that the area under the curve (AUC) of the risk nomogram model was 0.865 (95% CI: 0.755-0.948), with a sensitivity of 91.11% (82/90), specificity of 93.64% (103/110), and accuracy of 92.50% (185/200). The risk nomogram model demonstrated good fit (χ2 = 3.347, df = 7, P = 0.341), and the C-index of Bootstrap internal validation was 0.823.Conclusion: Age > 60 years, disease duration > 1 year, multiple stenosis segments, small median sagittal diameter, small cross-sectional area of the spinal canal, and shorter segment length are risk factors for secondary cauda equina injury in patients with lumbar spinal stenosis. The risk prediction model based on this nomogram has good clinical application value.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"299-306"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Use οf the Forging Alliances in Interdisciplinary Rehabilitation Research (FAIRR) Model to Develop an Intervention Using a Mixed Methods Approach. 利用跨学科康复研究锻造联盟（FAIRR）模型中的ο (ο)开发一种使用混合方法的干预方法。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Simone V Gill, Christine A Helfrich

引用次数: 0

Gender-Specific Relationships Between Ankle Mobility, Foot Strength, and Trunk Control in Futsal Players: A Cross-Sectional Study. 五人制足球运动员踝关节活动、足部力量和躯干控制之间的性别关系：一项横断面研究。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Íñigo Asurmendi, María Oficialdegui, Pedro J Marín

{"title":"Gender-Specific Relationships Between Ankle Mobility, Foot Strength, and Trunk Control in Futsal Players: A Cross-Sectional Study.","authors":"Íñigo Asurmendi, María Oficialdegui, Pedro J Marín","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: This study investigated the relationships between ankle dorsiflexion, first toe strength, and core stability in male and female futsal players.Methods: Fourteen male professional players from the Spanish first division and 22 female players from the second division were evaluated. Ankle dorsiflexion range of motion was measured using the LegMotion® system. Core stability was assessed via the OCTOcore app during single-leg deadlift (SLD) and bird-dog (BD) exercises. Toe flexor strength (TFS) was measured with a handheld dynamometer, and plantar flexor endurance was evaluated using the heel-raise test (HR). Statistical correlations were analyzed to explore neuromuscular relationships.Results: In males, a moderate positive correlation (p < 0.01) was found between ankle dorsiflexion and TFS, suggesting enhanced ankle mobility may increase toe strength. A negative correlation between TFS and SLD performance indicated stronger toe flexors correlated with better core stability. In females, a negative correlation between ankle dorsiflexion and BD performance implied greater ankle mobility improved core stability. Conversely, a positive correlation between TFS and SLD performance suggested stronger toe flexors were linked to poorer core stability.Conclusions: Ankle mobility and toe strength enhance core stability in males, while females employ distinct neuromuscular strategies, highlighting the need for gender-specific training programs.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"258-265"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of External Load on the Contribution of Tendon Dynamics During Stretch-Shortening Cycle Exercises. 外载荷对拉伸-缩短周期运动中肌腱动力学贡献的影响。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Takehiro Kosaka, Keitaro Kubo

{"title":"Effects of External Load on the Contribution of Tendon Dynamics During Stretch-Shortening Cycle Exercises.","authors":"Takehiro Kosaka, Keitaro Kubo","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: This study aimed to determine the effect of external load on the contribution of tendon lengthening during eccentric phase and tendon shortening velocity during concentric phase in stretch-shortening cycle exercises.Methods: Fifteen men performed no-countermovement jump (noCMJ) and countermovement jump (CMJ) using only ankle joint with three different loads (0, 30, and 70% of 1 repetition maximum (RM)). Mean torque, angular velocity, power, and fascicle length of the medial gastrocnemius muscle were measured during jumping. In addition, the relative differences in the measured variables of CMJ compared to noCMJ were defined as pre-stretch augmentation.Results: During concentric phase, the pre-stretch augmentation in angular velocity and power was significantly correlated with that in tendon shortening velocity (except for 70%1RM) but not in fascicle shortening velocity. The increases in tendon length during eccentric phase of CMJ were highly correlated with mean power during concentric phase for all load conditions.Conclusion: These results suggest that the tendon shortening velocity during concentric phase and the amount of tendon lengthening during eccentric phase (i.e., tendon dynamics) strongly contribute to increased performance in stretch-shortening exercises.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"266-275"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401464/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Validity and Reliability of the Athletic Shoulder Test: A Brief Systematic Review and Meta-Analysis. 运动员肩部测试的效度与信度：一个简短的系统回顾与元分析。

IF 1.6 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-09-01

Süleyman Ulupınar, İzzet İnce, Cebrail Gençoğlu, Selim Asan, Salih Çabuk, Serhat Özbay

{"title":"Validity and Reliability of the Athletic Shoulder Test: A Brief Systematic Review and Meta-Analysis.","authors":"Süleyman Ulupınar, İzzet İnce, Cebrail Gençoğlu, Selim Asan, Salih Çabuk, Serhat Özbay","doi":"","DOIUrl":"","url":null,"abstract":"This systematic review and meta-analysis aimed to synthesize the validity and reliability of the AST and explore its measurement precision through standard error of measurement (SEM) and minimal detectable change (MDC). A systematic search of PubMed, Scopus, and Web of Science databases was conducted to identify studies evaluating the AST's psychometric properties. Studies reporting quantitative validity or reliability data (e.g., correlation coefficients, ICC) were included. A random-effects meta-analysis was performed to pool validity and reliability estimates, with heterogeneity assessed using I2 and Tau2. SEM and MDC values were systematically reviewed to evaluate measurement precision. Seven studies were included in the systematic review, with five studies (42 validity estimates) and six studies (35 reliability estimates) contributing to the meta-analysis. The AST demonstrated promising levels of validity (pooled r = 0.923) and reliability (pooled r = 0.958), although substantial heterogeneity was observed (I2 > 85%) and should be considered when interpreting these findings. No significant publication bias was detected. SEM ranged from 0.85 - 20.43 N, and MDC from 2.37 - 56.63 N, indicating variable measurement precision. Overall, the AST appears to be a potentially useful tool for assessing shoulder function, with relevance for clinical and research applications.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 3","pages":"351-363"},"PeriodicalIF":1.6,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12401466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0