Journal of musculoskeletal & neuronal interactions最新文献_第2页

Increased Gait Variability while Texting and Walking with Added Cognitive Loads in Challenging Environments. 在具有挑战性的环境中，在认知负荷增加的情况下，发短信和走路时步态变异性增加。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-09-01

Chi-Whan Choi, Simone V Gill

{"title":"Increased Gait Variability while Texting and Walking with Added Cognitive Loads in Challenging Environments.","authors":"Chi-Whan Choi, Simone V Gill","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: This study investigated (1) whether additional cognitive loads impair dual-task walking, especially when crossing obstacles of varying heights, and (2) if extreme gradient boosting (XGBoost) could identify key features of walking while texting.Methods: Twenty participants completed the following conditions: baseline walking, Task (walking + Typing: copying sentences, or Texting: answering questions), Obstacle (walking + crossing obstacles of three heights: low, medium, high), and combined (Task + Obstacle). For texting performance, we computed the rate, accuracy, and dual-task cost (DTC). Gait measures included mean spatiotemporal parameters, coefficient of variation (%CV) for each parameter, and mediolateral trunk acceleration. Four machine learning models were trained for evaluation: K-Nearest Neighbor, Support Vector Machines, and Random Forest, XGBoost.Results: XGBoost achieved the best performance, with a test weighted F1 score of 0.848, and identified rate, %CV for step and stride time, and DTC of rate as the most important features for classification of conditions. Task × Obstacle interaction was found for %CV of step time with greater variability during high obstacle crossing while Texting (β=1.742, p=0.029).Conclusions: Findings demonstrate that mobile phone use increases walking variability, particularly in complex environments. The result may lend weight to growing concerns about mobile phone use while walking in young adults.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 3","pages":"317-338"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539739/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Correlation between Sagittal Lumbopelvic Control and Pain Sensitivity and Intensity in Chronic Lumbosacral Radiculopathy Female Patients: A Cross-Sectional Study. 慢性腰骶神经根病女性患者矢状面腰骨盆控制与疼痛敏感性和强度的相关性：一项横断面研究。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-09-01

Hend Refaat Kamal, Hoda M Zakaria, Ebtesam M Fahmy, Azza S A Khalil, Marwa Mostafa, Nagwa Ibrahim Rehab

{"title":"Correlation between Sagittal Lumbopelvic Control and Pain Sensitivity and Intensity in Chronic Lumbosacral Radiculopathy Female Patients: A Cross-Sectional Study.","authors":"Hend Refaat Kamal, Hoda M Zakaria, Ebtesam M Fahmy, Azza S A Khalil, Marwa Mostafa, Nagwa Ibrahim Rehab","doi":"","DOIUrl":"","url":null,"abstract":"Objective: Chronic lumbosacral radiculopathy (LSR) patients frequently complain of recurrent chronic lumbopelvic pain. The poor lumbopelvic (LP) control may be related to this chronic pain in LSR. We aimed to investigate the relation of sagittal LP control with pain sensitivity and intensity in chronic LSR females.Methods: This study included forty females with chronic unilateral discogenic LSR (30-46 years old). Their low back pain intensity was 6.87±1.02 by visual analogue scale (VAS). The sagittal LP control and pain sensitivity and intensity were assessed for all patients using a pressure biofeedback unit during prone hip extension task, a digital pressure algometer applied at low back area and four sciatic valleix spots, and the VAS, respectively.Results: A moderate significant negative relation was found between sagittal LP control and pain sensitivity at low back point (r = -0.48, p = 0.002). There was a moderate to strong significant negative relation between sagittal LP control and pain sensitivity at the different sciatic valleix spots. In addition, a strong positive correlation between poor sagittal LP control and pain intensity was found (r= 0.69, p < 0.001).Conclusion: Poor lumbopelvic control may be highly related with pain sensitivity and intensity in chronic LSR females.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 3","pages":"429-435"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539740/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The WNT/β-catenin Pathway and Matrix Metalloproteinase-9 in hypermobile Ehlers-Danlos Syndrome and Autism Spectrum Disorder: A Possible Connection. WNT/β-catenin通路和基质金属蛋白酶-9在超移动型Ehlers-Danlos综合征和自闭症谱系障碍中的可能联系

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-09-01

Anna C Douglas, Daniel J Staas

{"title":"The WNT/β-catenin Pathway and Matrix Metalloproteinase-9 in hypermobile Ehlers-Danlos Syndrome and Autism Spectrum Disorder: A Possible Connection.","authors":"Anna C Douglas, Daniel J Staas","doi":"","DOIUrl":"","url":null,"abstract":"Hypermobile Ehlers-Danlos Syndrome (hEDS), a connective tissue disorder also known as Ehlers-Danlos Syndrome Type III or Ehlers-Danlos Syndrome Hypermobility Type, and Autism Spectrum Disorder (ASD), a neurodevelopmental disorder, present notable symptom overlap and higher than expected level of comorbidity. A recent systematic review and meta-analysis found that the overall prevalence of joint hypermobility in autistic individuals was 22.3%, rising to 31% when clinically assessed. The overall prevalence of Ehlers-Danlos Syndrome or Hypermobility Spectrum Disorder was 27.9%, rising to 39% when clinically assessed rather than self-reported. This comorbidity is likely underrepresented due to factors including gender-related underdiagnosis, limited awareness, and fragmented care. Despite this, research at the disorders' intersection remains limited. In this narrative review, we aim to (i) examine hEDS and ASD from a clinical and molecular perspective; (ii) review literature regarding the WNT/β-catenin pathway and matrix metalloproteinases' involvement in fibroblast phenotypes, extracellular matrix regulation, and synaptogenesis; and (iii) evaluate how pathway dysregulation may connect each disorder's tissue and neurodevelopmental traits. Although both disorders remain pathophysiologically elusive, we hope to shed light on their co-occurrence and promote future research by exploring how these disorders are possibly linked, specifically via WNT/β-catenin and matrix metalloproteinase activity.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 3","pages":"466-481"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Postural Control Adjustments with Sensory Manipulations and External Perturbations in Older Adults: Electromyographic Analysis of Lower-limb & Trunk Muscles. 老年人体位控制调整与感觉操作和外部扰动：下肢和躯干肌肉的肌电图分析。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-09-01

Adnan Mohd Kr, Sarah Parveen, Chhavi Arora Sehgal, Syed Naznin Fatma, Fayaz Khan, Mashael Alsobhi, Md Dilshad Manzar, Majumi M Noohu

{"title":"Postural Control Adjustments with Sensory Manipulations and External Perturbations in Older Adults: Electromyographic Analysis of Lower-limb & Trunk Muscles.","authors":"Adnan Mohd Kr, Sarah Parveen, Chhavi Arora Sehgal, Syed Naznin Fatma, Fayaz Khan, Mashael Alsobhi, Md Dilshad Manzar, Majumi M Noohu","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To examine the influence of vision and somatosensory information on anticipatory postural adjustments (APA) and compensatory postural adjustments (CPA) in response to an external perturbation in older adults.Methods: Twenty healthy older adults were included in the study. Postural stability was tested under four different vision and surface support conditions using a sandbag drop while the participants were holding a tray. Electromyography (EMG) latency, amplitude amplitude - root mean square (RMS) of the erector spinae (ES) and lateral gastrocnemius (LG) muscles and centre of pressure (COP) displacement were recorded.Results: Significant differences in muscle activity and COP displacements were observed across visual and somatosensory conditions. LG activity and compensatory COP displacement (CPA-COP) were significantly greater under eyes-closed and unstable surface conditions (ECUS). This indicates that the absence of visual input and altered somatosensory feedback independently and collectively amplify compensatory postural responses. Anticipatory responses were less effective under sensory- compromised conditions.Conclusions: Both vision and somatosensory inputs critically influence APA and CPA in older adults. Visual deprivation and unstable surfaces reduce the efficiency of APA and heighten CPA, reflecting the need to address both systems in balance training.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 3","pages":"418-428"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539737/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Height-Specific Reference Centiles for Jumping Mechanography in Children: Retrospective Analysis of the DONALD Study Cohort. 儿童跳跃力学的身高特异性参考百分位：DONALD研究队列的回顾性分析。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-09-01

Maja Zimmermann, Jonathan Buggisch, Karoline Spiess, Eckhard Schönau, Ute Alexy, Ibrahim Duran

{"title":"Height-Specific Reference Centiles for Jumping Mechanography in Children: Retrospective Analysis of the DONALD Study Cohort.","authors":"Maja Zimmermann, Jonathan Buggisch, Karoline Spiess, Eckhard Schönau, Ute Alexy, Ibrahim Duran","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: Jumping mechanography is a common method to analyze muscle function. To date, mainly age- or weight-specific pediatric reference centiles for jumping mechanography have been published. The use of age-related references in children with small stature (defined as height below the age-specific third centile) might lead to misinterpretation of actual jumping performance. Thus, the study aim was the development of height-specific mechanography reference centiles of healthy children and show application in children with small stature.Methods: Data from 882 children (aged 6-18 years; height 100-200cm) from the DONALD cohort was analyzed using the LMS (lambda-mu-sigma)-method. Sex-specific centiles were calculated for maximal velocity (Vmax), Nerve-Muscle Index (NMI), maximal power (Pmax) and maximal force (Fmax), both related to body mass. Age- and height-specific jumping parameters were individually compared in healthy children with small stature.Results: Vmax, Pmax and NMI increased with higher stature until a plateau was reached. Fmax stayed rather stable over time. Age-specific z-scores of Vmax, Pmax and NMI in children with small stature were lower than the height-specific z-scores.Conclusions: In this article first height- and sex-specific reference centiles for jumping mechanography in healthy German children are presented. This study highlights the beneficial application of height-specific reference centiles for interpretation of jumping performance in children with small stature.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 3","pages":"339-354"},"PeriodicalIF":1.9,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13539745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148865327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Age Associations with Hamstring Tightness, Trunk Flexibility, and Lumbar Lordosis in Sedentary Adult Females: A Cross-Sectional Study. 年龄与久坐成年女性腿筋紧绷、躯干柔韧性和腰椎前凸的关系：一项横断面研究。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-06-01

Nesma M Allam, Norah Zayed Alanazi, Tuqa Amin Alsattam, Taif Nawaf Asharari, Aeshah Abdulhakim Alowaydhah, Rahaf Nazzal Alfalah, Khuzama Tariq Alghali, Angham Mohammed Alsaleem, Thikra Mamdouh Alsirhani, Najah Saad Alshammari, Milaf Hashel Alsharari

{"title":"Age Associations with Hamstring Tightness, Trunk Flexibility, and Lumbar Lordosis in Sedentary Adult Females: A Cross-Sectional Study.","authors":"Nesma M Allam, Norah Zayed Alanazi, Tuqa Amin Alsattam, Taif Nawaf Asharari, Aeshah Abdulhakim Alowaydhah, Rahaf Nazzal Alfalah, Khuzama Tariq Alghali, Angham Mohammed Alsaleem, Thikra Mamdouh Alsirhani, Najah Saad Alshammari, Milaf Hashel Alsharari","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: To determine the relationship between age, hamstring tightness, trunk flexibility, and lumbar lordosis angle (LLA), and examine how these variables relate independently of age. Furthermore, we identified the most significant predictor of LLA in sedentary adult females with hamstring tightness.Methods: This cross-sectional study included 80 sedentary adult females (20-59 years old) with hamstring tightness, which was assessed using the active knee extension (AKE) and straight leg raising (SLR) tests with a universal goniometer. Trunk flexibility was assessed using the fingertip-to-floor test, and the LLA was evaluated non-radiographically using a flexicurve (flexible ruler).Results: A significant correlation was observed between age and all examined variables (p < 0.001). Specifically, age was associated with increased fingertip-to-floor distance, suggesting reduced trunk flexibility (β = 0.756), and increased SLR (β = 0.517) and AKE (β = 0.424) angles, indicating increased hamstring tightness. Furthermore, age was the significant independent predictor (p < 0.001) of LLA.Conclusions: Age is significantly correlated with decreased flexibility and reduced lumbar lordosis angle in adult females. Among the variables examined, age was the significant independent predictor of LLA. These findings highlight the need for early detection and management of age-related musculoskeletal alterations to maintain proper spinal alignment and functional mobility.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 2","pages":"225-233"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Quantitative Analysis of Spontaneous Tongue Muscle Reinnervation after Long Nerve Resection for Hypoglossal Nerve Injury in Rats. 舌下神经损伤大鼠长神经切除后舌肌自发神经重建的定量分析。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-06-01

Nanae Fukushima, Norimi Sumitomo, Ayata Nagira, Yuko Ichinose, Akira Kakegawa, Tetsuji Moriizumi

{"title":"Quantitative Analysis of Spontaneous Tongue Muscle Reinnervation after Long Nerve Resection for Hypoglossal Nerve Injury in Rats.","authors":"Nanae Fukushima, Norimi Sumitomo, Ayata Nagira, Yuko Ichinose, Akira Kakegawa, Tetsuji Moriizumi","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: This study aimed to investigate spontaneous tongue muscle reinnervation after long nerve resection for severe hypoglossal (XII) nerve injury in adult rats.Methods: The right XII nerve was exposed, and a 9-mm section was resected. The tongue was removed and cut coronally at 4, 8, and 12 weeks after the XII nerve resection. The sections were processed for immunohistochemical staining for vesicular acetylcholine transporter (VAChT) to detect the regenerated right XII and the uninjured left XII nerve terminals. The numbers of VAChT-positive nerve terminals were counted on the injured right and uninjured left sides, and the reinnervation rate, which is the percentages of the number of VAChT-positive nerve terminals on the injured side relative to that on the uninjured side, was calculated.Results: The injured XII nerve gradually regenerated in the tongue after the nerve resection. The reinnervation rates in nerve-resected rats were significantly lower than those in normal rats, with mean reinnervation rates of 13.9%, 37.9%, and 41.8% at 4, 8, and 12 weeks after nerve resection, respectively.Conclusion: Spontaneous reinnervation occurred in the tongue muscle after the XII nerve injury with long nerve resection and injured nerve terminals regenerated approximately 40% of the normal value; this rate was considerably lower than that with the nerve transection.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 2","pages":"293-300"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223789/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acoustic Radiation Force Impulse (ARFI) Elastography as a diagnostic and monitoring tool for Bell's palsy: A Prospective Study. 声辐射力脉冲（ARFI）弹性成像作为贝尔麻痹的诊断和监测工具：一项前瞻性研究。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-06-01

Murat Toprak, Nurşen Toprak, Mehmet Reşit Oncu, Abdussamet Batur, Abdullah Yılgor, Nazım Bozan

{"title":"Acoustic Radiation Force Impulse (ARFI) Elastography as a diagnostic and monitoring tool for Bell's palsy: A Prospective Study.","authors":"Murat Toprak, Nurşen Toprak, Mehmet Reşit Oncu, Abdussamet Batur, Abdullah Yılgor, Nazım Bozan","doi":"","DOIUrl":"","url":null,"abstract":"Objective: To evaluate ARFI elastography as a diagnostic and monitoring tool in Bell's palsy by comparing affected and unaffected facial muscles, pre- and post-treatment.Methods: Thirty patients with Bell's palsy (17 females and 13 males, mean age 44.6 ± 16.76, range:18-72 years) were assessed using Clinical (House-Brackmann grading), electrophysiologic (EMG), and ultrasonographic (ARFI-elastography). In order to assess the diagnostic value of elastosonography, we compared the scores between the paretic and nonparetic sides of the face. Measurements were obtained bilaterally at baseline and after four weeks of physical therapy.Results: The initial degree of facial nerve paralysis was 5.13 ± 0.89 on the House-Brackmann scale (range 4-6). This parameter significantly decreased after the treatment, measuring 2.53 ± 0.81. Post-treatment, significant improvements were observed in EMG and ARFI values, particularly in the orbicularis oculi and masseter muscles. No significant correlation was found between EMG and ARFI elastographic parameters.Conclusions: ARFI elastography is a promising, non-invasive tool for monitoring Bell's palsy recovery, though standardization is needed.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 2","pages":"252-258"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toe Grasp Strength and Its Association with Muscle Mass and Calcaneal Bone Status in Young Adults: A Cross-Sectional Study. 一项横断面研究：年轻成人脚趾握力及其与肌肉质量和跟骨状态的关系。

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-06-01

Toshifumi Fujiwara, Motoki Koga, Ryosuke Yamaguchi, Nobuhiko Yokoyama, Yasuharu Nakashima

{"title":"Toe Grasp Strength and Its Association with Muscle Mass and Calcaneal Bone Status in Young Adults: A Cross-Sectional Study.","authors":"Toshifumi Fujiwara, Motoki Koga, Ryosuke Yamaguchi, Nobuhiko Yokoyama, Yasuharu Nakashima","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: The aim of this study was to investigate associations between toe grasp strength (TGS), skeletal muscle mass, and calcaneal bone status in young adults, and to determine whether TGS independently associates with musculoskeletal parameters.Methods: This cross-sectional study included 150 healthy young adults (118 males, 32 females; median age: 23 years). TGS was assessed using a standardized toe grasp dynamometer. Skeletal muscle mass was measured by bioelectrical impedance analysis (InBody 570), and calcaneal bone status was evaluated using quantitative ultrasound, expressed as standardized speed of sound (s-SOS). Associations between TGS, skeletal muscle index (SMI), and s-SOS were examined using correlation and multivariable regression analyses, with sex-stratified analyses.Results: Significant sex differences were observed in TGS, SMI, and s-SOS, with males showing higher values. In males, TGS was positively associated with both SMI and s-SOS. Multivariable analyses showed that higher TGS and younger age were independently associated with greater SMI and s-SOS in males. No significant associations were observed in females.Conclusions: In males, higher TGS is associated with greater skeletal muscle mass and better calcaneal bone status, suggesting that lower limb muscle strength reflects musculoskeletal status during early adulthood. Longitudinal studies are required to further clarify these associations.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 2","pages":"213-224"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223787/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Sensory Re-education Paradigm on Quality of Life, Tactile Sensation, and Proprioceptive Acuity in Patients with Post-COVID-19 Polyneuropathy: A Randomized Controlled Trial. 感觉再教育模式对covid -19后多发性神经病变患者生活质量、触觉和本体感觉敏锐度的影响：一项随机对照试验

IF 1.9 4区医学

Journal of musculoskeletal & neuronal interactions Pub Date : 2026-06-01

Hossam M Alsaid, Younes A Khadour, Hoda M Zakaria, Ebtesam M Fahmy, Fater A Khadour, Rehab S Mamoon, Azza S A Khalil, Walaa M Ragab, Ashraf A Darwesh, Mohamed G Ali

{"title":"Impact of Sensory Re-education Paradigm on Quality of Life, Tactile Sensation, and Proprioceptive Acuity in Patients with Post-COVID-19 Polyneuropathy: A Randomized Controlled Trial.","authors":"Hossam M Alsaid, Younes A Khadour, Hoda M Zakaria, Ebtesam M Fahmy, Fater A Khadour, Rehab S Mamoon, Azza S A Khalil, Walaa M Ragab, Ashraf A Darwesh, Mohamed G Ali","doi":"","DOIUrl":"","url":null,"abstract":"Objectives: This study evaluated the effect of sensory re-education on quality of life and sensation in patients with post-COVID-19 polyneuropathy.Methods: Forty patients with post-COVID-19 polyneuropathy were randomly assigned to a study group (Group A) or a control group (Group B), each with 20 participants. Group A received a sensory re-education protocol plus the traditional physiotherapy, including proprioceptive neuromuscular facilitation (PNF) and strengthening exercises for wrist extensors, hand grip, and thumb opposition. Group B received the traditional physiotherapy alone. Both groups were treated for one hour, three times weekly, for six weeks. Quality of life was assessed using the Arabic WHOQOL-BREF. Tactile sensation was assessed using the Semmes-Weinstein Monofilament (SWM) test, and proprioception via the laser-pointer angle reproduction test (LP-ART). Assessments were performed pre- and post-intervention.Results: Both groups showed significant pre- to post-treatment improvements in quality of life, proprioception, and tactile sensation (p≤ 0.05). Group A demonstrated significantly greater gains in quality of life and proprioception compared to Group B (p≤ 0.05), but no statistically significant difference between groups in tactile sensation (p> 0.05).Conclusion: Sensory re-education, when integrated into traditional physiotherapy, significantly improves quality of life and proprioception in post-COVID-19 polyneuropathy but does not significantly affect tactile sensation. These findings support incorporating sensory re-education into rehabilitation protocols to enhance functional outcomes in this population.Clinicaltrials: gov ID: NCT05911113.","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"26 2","pages":"242-251"},"PeriodicalIF":1.9,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13223784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148138400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0