Alessandro Uono Sanchez, Altair Gustavo Saura Martins, Ana Patricia Montebello Medeiros Bahé, Francisco Oliveira Zucchi, Moacir Miguel Borges de Almeida, Múcio Brandão Vaz de Almeida, Rodrigo Mendes Heilmann, Sabrina Giovana Cavalcanti Lucas, Vanessa Van der Linden, Epitácio Leite Rolim Filho
{"title":"先天性寨卡病毒综合征儿童的大运动功能和肌肉骨骼畸形","authors":"Alessandro Uono Sanchez, Altair Gustavo Saura Martins, Ana Patricia Montebello Medeiros Bahé, Francisco Oliveira Zucchi, Moacir Miguel Borges de Almeida, Múcio Brandão Vaz de Almeida, Rodrigo Mendes Heilmann, Sabrina Giovana Cavalcanti Lucas, Vanessa Van der Linden, Epitácio Leite Rolim Filho","doi":"","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>The objective of the present study was to assess gross motor function and describe musculoskeletal deformities in patients diagnosed with Congenital zika syndrome (CZS).</p><p><strong>Methods: </strong>This is a cross-sectional study, carried out at the Association for Assistance of Disabled Children (AACD) in Pernambuco, Brazil, between June 2017 and April 2023. Medical records and assessments were carried out to describe musculoskeletal deformities and measure gross motor function, using the GMFM-88.</p><p><strong>Results: </strong>The study included 37 patients between 1 and 2 years old, 56.8% infected during the first trimester of pregnancy. The patients' mean GMFM value was 5.63 and standard deviation was 6.37. A moderate correlation was observed between head circumference at birth and the patients' current gross motor function (Pearson coeficient = 0.594) (p<0.001). We also observed 19 types of deformities, which were more prevalent in the lower limbs.</p><p><strong>Conclusion: </strong>CZS brings significant impairments to motor function and the musculoskeletal system. In this context, measuring head circumference at birth can serve as a predictor of impaired gross motor function in these children.</p>","PeriodicalId":16430,"journal":{"name":"Journal of musculoskeletal & neuronal interactions","volume":"25 2","pages":"172-177"},"PeriodicalIF":1.6000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131074/pdf/","citationCount":"0","resultStr":"{\"title\":\"Gross Motor Function and Musculoskeletal Deformities in Children With Congenital Zika Virus Syndrome.\",\"authors\":\"Alessandro Uono Sanchez, Altair Gustavo Saura Martins, Ana Patricia Montebello Medeiros Bahé, Francisco Oliveira Zucchi, Moacir Miguel Borges de Almeida, Múcio Brandão Vaz de Almeida, Rodrigo Mendes Heilmann, Sabrina Giovana Cavalcanti Lucas, Vanessa Van der Linden, Epitácio Leite Rolim Filho\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>The objective of the present study was to assess gross motor function and describe musculoskeletal deformities in patients diagnosed with Congenital zika syndrome (CZS).</p><p><strong>Methods: </strong>This is a cross-sectional study, carried out at the Association for Assistance of Disabled Children (AACD) in Pernambuco, Brazil, between June 2017 and April 2023. Medical records and assessments were carried out to describe musculoskeletal deformities and measure gross motor function, using the GMFM-88.</p><p><strong>Results: </strong>The study included 37 patients between 1 and 2 years old, 56.8% infected during the first trimester of pregnancy. The patients' mean GMFM value was 5.63 and standard deviation was 6.37. A moderate correlation was observed between head circumference at birth and the patients' current gross motor function (Pearson coeficient = 0.594) (p<0.001). We also observed 19 types of deformities, which were more prevalent in the lower limbs.</p><p><strong>Conclusion: </strong>CZS brings significant impairments to motor function and the musculoskeletal system. In this context, measuring head circumference at birth can serve as a predictor of impaired gross motor function in these children.</p>\",\"PeriodicalId\":16430,\"journal\":{\"name\":\"Journal of musculoskeletal & neuronal interactions\",\"volume\":\"25 2\",\"pages\":\"172-177\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12131074/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of musculoskeletal & neuronal interactions\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of musculoskeletal & neuronal interactions","FirstCategoryId":"3","ListUrlMain":"","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
Gross Motor Function and Musculoskeletal Deformities in Children With Congenital Zika Virus Syndrome.
Objectives: The objective of the present study was to assess gross motor function and describe musculoskeletal deformities in patients diagnosed with Congenital zika syndrome (CZS).
Methods: This is a cross-sectional study, carried out at the Association for Assistance of Disabled Children (AACD) in Pernambuco, Brazil, between June 2017 and April 2023. Medical records and assessments were carried out to describe musculoskeletal deformities and measure gross motor function, using the GMFM-88.
Results: The study included 37 patients between 1 and 2 years old, 56.8% infected during the first trimester of pregnancy. The patients' mean GMFM value was 5.63 and standard deviation was 6.37. A moderate correlation was observed between head circumference at birth and the patients' current gross motor function (Pearson coeficient = 0.594) (p<0.001). We also observed 19 types of deformities, which were more prevalent in the lower limbs.
Conclusion: CZS brings significant impairments to motor function and the musculoskeletal system. In this context, measuring head circumference at birth can serve as a predictor of impaired gross motor function in these children.
期刊介绍：
The Journal of Musculoskeletal and Neuronal Interactions (JMNI) is an academic journal dealing with the pathophysiology and treatment of musculoskeletal disorders. It is published quarterly (months of issue March, June, September, December). Its purpose is to publish original, peer-reviewed papers of research and clinical experience in all areas of the musculoskeletal system and its interactions with the nervous system, especially metabolic bone diseases, with particular emphasis on osteoporosis. Additionally, JMNI publishes the Abstracts from the biannual meetings of the International Society of Musculoskeletal and Neuronal Interactions, and hosts Abstracts of other meetings on topics related to the aims and scope of JMNI.
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