Gross Motor Function and Musculoskeletal Deformities in Children With Congenital Zika Virus Syndrome.

IF 1.6 4区医学 Q4 NEUROSCIENCES

Journal of musculoskeletal & neuronal interactions Pub Date : 2025-06-01

Alessandro Uono Sanchez, Altair Gustavo Saura Martins, Ana Patricia Montebello Medeiros Bahé, Francisco Oliveira Zucchi, Moacir Miguel Borges de Almeida, Múcio Brandão Vaz de Almeida, Rodrigo Mendes Heilmann, Sabrina Giovana Cavalcanti Lucas, Vanessa Van der Linden, Epitácio Leite Rolim Filho

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引用次数: 0

Abstract

Objectives: The objective of the present study was to assess gross motor function and describe musculoskeletal deformities in patients diagnosed with Congenital zika syndrome (CZS).

Methods: This is a cross-sectional study, carried out at the Association for Assistance of Disabled Children (AACD) in Pernambuco, Brazil, between June 2017 and April 2023. Medical records and assessments were carried out to describe musculoskeletal deformities and measure gross motor function, using the GMFM-88.

Results: The study included 37 patients between 1 and 2 years old, 56.8% infected during the first trimester of pregnancy. The patients' mean GMFM value was 5.63 and standard deviation was 6.37. A moderate correlation was observed between head circumference at birth and the patients' current gross motor function (Pearson coeficient = 0.594) (p<0.001). We also observed 19 types of deformities, which were more prevalent in the lower limbs.

Conclusion: CZS brings significant impairments to motor function and the musculoskeletal system. In this context, measuring head circumference at birth can serve as a predictor of impaired gross motor function in these children.

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先天性寨卡病毒综合征儿童的大运动功能和肌肉骨骼畸形

目的：本研究的目的是评估先天性寨卡综合征（CZS）患者的大运动功能和描述肌肉骨骼畸形。方法：这是一项横断面研究，于2017年6月至2023年4月在巴西伯南布哥州的残疾儿童援助协会（AACD）进行。使用GMFM-88进行医疗记录和评估，以描述肌肉骨骼畸形和测量大运动功能。结果：本研究纳入37例1 ~ 2岁患者，56.8%在妊娠前三个月感染。患者GMFM均值为5.63，标准差为6.37。出生时头围与患者目前的大运动功能有中等相关性（Pearson系数= 0.594）。结论：cz综合征对运动功能和肌肉骨骼系统有明显的损害。在这种情况下，出生时测量头围可以作为这些儿童大运动功能受损的预测指标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of musculoskeletal & neuronal interactions NEUROSCIENCES-PHYSIOLOGY

CiteScore

3.40

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The Journal of Musculoskeletal and Neuronal Interactions (JMNI) is an academic journal dealing with the pathophysiology and treatment of musculoskeletal disorders. It is published quarterly (months of issue March, June, September, December). Its purpose is to publish original, peer-reviewed papers of research and clinical experience in all areas of the musculoskeletal system and its interactions with the nervous system, especially metabolic bone diseases, with particular emphasis on osteoporosis. Additionally, JMNI publishes the Abstracts from the biannual meetings of the International Society of Musculoskeletal and Neuronal Interactions, and hosts Abstracts of other meetings on topics related to the aims and scope of JMNI.