Journal of International Medical Research最新文献

{"title":"A male patient with atrial myxoma and multiple metastatic intracranial aneurysms: A case report and literature review.","authors":"Min Xia, Yi Wang, Xuefeng An, Yufeng Huang, Ke Wei, Jia Zhou, Kun Li, Guojie Yao, He Huang","doi":"10.1177/03000605251333690","DOIUrl":"https://doi.org/10.1177/03000605251333690","url":null,"abstract":"<p><p>Atrial myxoma is the most common primary benign tumor of the heart, with over 75% occurring in the left atrium. The migration of myxoma cells can lead to rare neurological complications such as intracranial aneurysms, embolic strokes, and arteriovenous malformations. The most common neurological manifestations in such patients include seizures, nonspecific headaches, and cerebrovascular events. Herein, we present a rare case of a middle-aged man in his early 50s with metastatic myxomatous multiple fusiform aneurysms, who initially presented with the clinical manifestation of intracerebral hemorrhage. The patient underwent atrial myxoma resection, whereas the intracranial multiple fusiform aneurysms were managed conservatively. Four years later, digital subtraction angiography revealed progressive enlargement of the aneurysm in the A3 segment of the left anterior cerebral artery. We present the pathological report of the atrial myxoma and imaging findings showing the changes in the aneurysms, along with a review and summary of the relevant literature. This report offers new insights into treatment options for cases of atrial myxoma complicated with intracranial multiple aneurysms. This is the first reported case of a male patient in China presenting with intracerebral hemorrhage as the initial manifestation of atrial myxoma combined with multiple fusiform aneurysms.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251333690"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035032/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel cancer-associated fibroblast-related gene signature for predicting diffuse large B cell lymphoma prognosis using weighted gene co-expression network analysis and machine learning.","authors":"Hongxia Cui, Menglu Chen, Meifang Zhao, Bingzong Li","doi":"10.1177/03000605251331250","DOIUrl":"https://doi.org/10.1177/03000605251331250","url":null,"abstract":"<p><p>ObjectiveOur objective was to investigate a novel cancer-associated fibroblast-related gene signature for predicting clinical outcomes in patients with diffuse large B cell lymphoma.MethodsThe cancer-associated fibroblast-related module genes were identified from Gene Expression Omnibus datasets using weighted gene co-expression network analysis in our retrospective study. Least Absolute Shrinkage and Selection Operator Cox regression was applied to screen a minimal set of genes and construct a prognostic cancer-associated fibroblast-related gene signature for diffuse large B cell lymphoma. Kaplan-Meier plots and receiver operating characteristic curves were used to assess the prognostic performance of the prognostic cancer-associated fibroblast-related genes. A nomogram encompassing the clinical information and prognostic scores of the patients was constructed. Additionally, the relationships of the gene signature with the immune landscape and drug sensitivity were explored.ResultsCapitalizing on machine learning, we developed a prognostic cancer-associated fibroblast-related gene signature risk model, efficiently categorizing patients with diffuse large B cell lymphoma into high- and low-risk groups and exhibiting a more robust capacity for survival prediction. The nomogram showed stronger prognostic ability than the clinical factor-based model or the risk score alone. We also observed significant differences in immune cell profiles and therapeutic responses between the two groups, offering valuable insights for developing personalized treatments for diffuse large B cell lymphoma.ConclusionsWe developed a prognostic cancer-associated fibroblast-related gene-based genetic risk model to predict the prognosis of diffuse large B cell lymphoma, potentially aiding in treatment selection.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251331250"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144022385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of male androgenetic alopecia on a Jordanian cohort measured using the Dermatology Life Quality Index.","authors":"Jihan Muhaidat, Sakhr Alshwayyat, Haya Kamal, Zena Haddadin, Almutazballlah Qablan, Hanadi Qeyam, Firas Al-Qarqaz","doi":"10.1177/03000605251332799","DOIUrl":"https://doi.org/10.1177/03000605251332799","url":null,"abstract":"<p><p>ObjectivesThis study aimed to assess the impact of androgenetic alopecia on the quality of life of individuals in a Jordanian cohort using the Dermatology Life Quality Index and compare it with that in other communities.MethodsThis cross-sectional study recruited men from different age groups with varying extent of androgenetic alopecia. The participants' demographics were documented using the Dermatology Life Quality Index questionnaire. The severity of androgenetic alopecia was assessed using the Hamilton-Norwood scale.ResultsA total of 522 participants were included in this study. The mean Dermatology Life Quality Index of the cohort was 1.5. The main burden was a feeling of embarrassment. A greater impact of androgenetic alopecia was noted in younger age groups than in older age groups, while participants who had had the disease for a longer duration (>10 years) showed significantly milder effects.ConclusionOur study found a minor impact of androgenetic alopecia on the quality of life of individuals in a Jordanian cohort. This could be attributed to the high prevalence of the condition and its cultural tolerance. This result should be interpreted with caution, as our study was conducted on the general population, whereas other studies have focused on individuals seeking treatment for androgenetic alopecia.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251332799"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12048751/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143967875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical outcomes of Nice knot-assisted locking plate for preserving periosteum internal fixation in comminuted clavicle fractures: A retrospective study.","authors":"Jingquan Guo, Bo Wu, Fei Xiao, Keke Cheng, Tianrun Lei","doi":"10.1177/03000605251328617","DOIUrl":"https://doi.org/10.1177/03000605251328617","url":null,"abstract":"<p><p>IntroductionClavicular fractures, particularly comminuted fractures, are common injuries that can affect shoulder function and upper limb mobility. The management of these fractures, especially using surgical approaches and fixation methods, remains a key area of clinical focus. Preserving the periosteum during surgery may improve fracture healing and reduce complications. This study explored the clinical efficacy of a periosteum-preserving surgical technique combined with a Nice knot-assisted locking plate for treating comminuted clavicular fractures.MethodsA total of 85 patients with comminuted clavicular fractures were included in this retrospective study. According to the Allman classification, 56 (65.9%) cases were type IC, 19 (22.4%) were type II, 9 (10.9%) were type III, and 1 (1.1%) involved comminuted fractures across the entire clavicle. All patients underwent surgical treatment using a periosteum-preserving approach combined with a Nice knot-assisted locking plate. Fracture healing time, upper limb function (measured via Constant-Murley score and disabilities of the arm, shoulder, and hand questionnaire), and postoperative complications were assessed 6 and 12 months postoperatively.ResultsThe median healing time was 13 weeks, with no cases of nonunion reported. At 6 months postoperatively, the Constant-Murley and disabilities of the arm, shoulder, and hand scores were excellent. Although a statistically significant difference (P < 0.05) was observed in these scores between 6 and 12 months, all patients reported satisfactory recovery of shoulder function and upper limb mobility. No significant differences (P > 0.05) in fracture healing time or upper limb function recovery were observed across different types of clavicular fractures. Six (7.1%) patients experienced temporary numbness in the subclavian region, which gradually resolved by the final follow-up.ConclusionThe periosteum-preserving approach with Nice knot-assisted locking plate fixation proved to be an effective and reliable treatment for comminuted clavicular fractures. The technique was associated with favorable healing times, excellent functional outcomes, and low complication rates. Preservation of the periosteum and soft tissue during surgery may considerably reduce intraoperative trauma and improve postsurgical recovery. Further studies with larger sample sizes and longer follow-up periods are needed to confirm the long-term benefits of this approach.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251328617"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143970156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence-powered four-fold upscaling of human brain synthetic metabolite maps.","authors":"Erin B Bjørkeli, Jonn T Geitung, Morteza Esmaeili","doi":"10.1177/03000605251330578","DOIUrl":"https://doi.org/10.1177/03000605251330578","url":null,"abstract":"<p><p>ObjectiveCompared with anatomical magnetic resonance imaging modalities, metabolite images from magnetic resonance spectroscopic imaging often suffer from low quality and detail due to their larger voxel sizes. Conventional interpolation techniques aim to enhance these low-resolution images; however, they frequently struggle with issues such as edge preservation, blurring, and input quality limitations. This study explores an artificial intelligence-driven approach to improve the quality of synthetically generated metabolite maps.MethodsUsing an open-access database of 450 participants, we trained and tested a model on 350 participants, evaluating its performance against spline and nearest-neighbor interpolation methods. Metrics such as structural similarity index, peak signal-to-noise ratio, and learned perceptual image patch similarity were used for comparison.ResultsOur model not only increased spatial resolution but also preserved critical image details, outperforming traditional interpolation methods in both image fidelity and edge preservation.ConclusionsThis artificial intelligence-powered super-resolution technique could substantially enhance magnetic resonance spectroscopic imaging quality, aiding in more accurate neurological assessments.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251330578"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035488/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144015366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Systemic anticoagulation in progressive chronic kidney disease and atrial fibrillation.","authors":"Henning Hansen-Nootbaar, Friedrich Stasche, Oliver Ritter, Daniel Patschan","doi":"10.1177/03000605251333306","DOIUrl":"https://doi.org/10.1177/03000605251333306","url":null,"abstract":"<p><p>ObjectivePatients with chronic kidney disease are at high risk of developing atrial fibrillation. However, it remains unclear whether systemic anticoagulants should be utilized, particularly in the later stages of chronic kidney disease.MethodsThis retrospective observational cohort study included patients with chronic kidney disease of various etiologies. This study aimed to record the prevalence of atrial fibrillation, use of systemic anticoagulation, and incidence of thromboembolic events and bleeding events among these patients.ResultsA total of 146 patients with chronic kidney disease were included in this study, with 43.8% of them experiencing atrial fibrillation. There was no significant difference in the prevalence of atrial fibrillation across various stages of chronic kidney disease. Thromboembolic events were not common in patients with atrial fibrillation but were prevalent in those with late-stage chronic kidney disease. Furthermore, patients with atrial fibrillation experienced a higher frequency of bleeding events, with the highest incidence observed in chronic kidney disease stage IV.ConclusionsAs systemic anticoagulation did not lower the frequency of thromboembolic events in patients with chronic kidney disease and atrial fibrillation in our study and considering that these patients experienced a higher frequency of bleeding complications, the use of systemic anticoagulants should be approached with caution, particularly in the later stages of chronic kidney disease.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251333306"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035191/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143985009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The cardiovascular effects of interleukin-6 inhibition in patients with severe coronavirus-19 infection.","authors":"Michael S Binder, Clinton Timmerman, Biwar Marof, Yingxing Wu, Adegbenga Bankole, Ido Heletz","doi":"10.1177/03000605251324590","DOIUrl":"10.1177/03000605251324590","url":null,"abstract":"<p><p>ObjectiveThe coronavirus disease 2019 (COVID-19) pandemic illustrated the relationship between cardiac arrhythmias and pro-inflammatory states. Pro-inflammatory cytokines, including interleukin-6 (IL-6), have significant effects on cardiac conduction. Atrial or ventricular arrhythmias occurring while infected results in a doubling of mortality. Tocilizumab, a monoclonal antibody that blocks the IL-6 receptor, is associated with improved mortality and is believed to be related to immune modulation of the COVID-19-related hyperinflammatory state.MethodsA single-center retrospective review of all patients with severe COVID-19, defined as admission to an intensive care unit or requirement of respiratory or circulatory support, from March 2020 through March 2022, was conducted. Patients who received or did not receive tocilizumab were grouped into the treatment and control groups, respectively.ResultsFour hundred seventy-three patients were reviewed and 400 met the criteria for inclusion in our study. There were 305 patients (age, 63 ± 13 years, 58% male) in the control group and 95 (age, 57 ± 15 years, 51% male) in the treatment group. In-hospital mortality was greatly reduced with tocilizumab compared with controls (44.2% vs 85.9%, p < 0.001) and new-onset atrial fibrillation (AF) showed a statistically significant reduction (17.8% vs 29.5%, p = 0.019). New-onset wall motion abnormalities, potentially related to myocarditis or acute coronary syndrome, also trended toward significance with tocilizumab (7.7% vs 15.7%, p = 0.10). Deep vein thrombosis, pulmonary embolism, stroke, and sustained ventricular arrhythmias did not meet statistical significance.ConclusionAs expected, tocilizumab did show significant improvement in mortality. Tocilizumab also showed a significant reduction of new-onset AF. Other cardiac structural endpoints did not reach statistical significance.<u>Abstract Presentations</u>A preliminary version of this research was presented during a regional conference at the Mid-Atlantic Capital Cardiology Symposium (MACCS) on 19 November 2023.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251324590"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11967226/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143772448","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prediction of postoperative recurrence of perianal fistulizing Crohn's disease by fecal calprotectin combined with serum miRNA6086.","authors":"Shengnan Jin, Maozhen Zhang, Dongdong Gu, Xingping Zhu, Zuolei Wang, Xuerong Shi, Yanping Hao, Su Xu","doi":"10.1177/03000605251328245","DOIUrl":"https://doi.org/10.1177/03000605251328245","url":null,"abstract":"<p><p>ObjectivesThis study aimed to identify risk factors for postoperative recurrence in patients with perianal fistulizing Crohn's disease and assess the predictive value of fecal calprotectin and serum miRNA6086.MethodsFrom 105 patients with perianal fistulizing Crohn's disease, blood and fecal samples as well as clinical data were collected. Analysis of blood tests, C-reactive protein, miRNA6086, and fecal calprotectin revealed postoperative recurrence risk factors. Receiver operating characteristic curve analysis assessed the predictive accuracy of miRNA6086 and fecal calprotectin for perianal fistulizing Crohn's disease recurrence and determined their optimal cutoff values, sensitivity, and specificity.ResultsOf the 105 patients with perianal fistulizing Crohn's disease, 33 (31.4%) experienced recurrence. Anal fistula type, preoperative miRNA6086, and fecal calprotectin levels were identified as independent risk factors for postoperative recurrence. Receiver operating characteristic curve analysis revealed that miRNA6086 had a cutoff value of 0.3195, sensitivity of 65.28%, specificity of 66.67%, and area under curve value of 0.6589 (95% confidence interval, 0.5503-0.7674). Fecal calprotectin had a cutoff value of 0.6073, sensitivity of 81.94%, specificity of 78.79%, and area under curve value of 0.8224 (95% confidence interval, 0.5503-0.7674). Combined miRNA6086 and fecal calprotectin detection had a cutoff value of 0.7121, sensitivity of 83.33%, specificity of 87.88%, and area under curve value of 0.9146 (95% confidence interval, 0.8547-0.9744).ConclusionAnal fistula type, preoperative miRNA6086, and fecal calprotectin levels are independent risk factors for perianal fistulizing Crohn's disease recurrence. Combined detection of miRNA6086 and fecal calprotectin levels enhances predictive accuracy for postoperative recurrence.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251328245"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144029416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pentalogy of Fallot: A case report.","authors":"Zhixiong Zhong, Ting Wen","doi":"10.1177/03000605251334463","DOIUrl":"https://doi.org/10.1177/03000605251334463","url":null,"abstract":"<p><p>We report the case of a 45-year-old woman with pentalogy of Fallot, a severe and complicated cyanotic congenital heart disease. Congenital anomalies of pentalogy of Fallot include ventricular septal defect, right ventricular hypertrophy, saddle aorta, pulmonary ostium stenosis, atrial septal defect, and patent foramen ovale. Pentalogy of Fallot is less common than triplet and tetralogy of Fallot and can affect children's physical development. Approximately 95% of patients with pentalogy of Fallot die before the age of 40 years, and early surgical radical surgery is recommended. However, the patient in the current case did not undergo surgery.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251334463"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038205/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143974643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Anti-glomerular basement membrane disease superimposed on membranous nephropathy after coronavirus disease 2019: A case report.","authors":"Rongrong Hu, Siqi Tang, Chao Li, Yizhen Wei, Peng Xia, Ke Zheng, Yan Qin","doi":"10.1177/03000605251335843","DOIUrl":"https://doi.org/10.1177/03000605251335843","url":null,"abstract":"<p><p>Membranous nephropathy concurrent with anti-glomerular basement membrane disease is rarely reported. Acute kidney injury is prominent when these diseases coexist. Coronavirus disease 2019 may trigger this superimposition. Herein, we report the case of a 60-year-old woman with pathologically confirmed anti-phospholipase A2 receptor-associated membranous nephropathy. She experienced complete remission of membranous nephropathy after non-immunosuppressive treatment. One month before admission, she experienced fever and her coronavirus disease 2019 antigen test was positive. She developed gross hematuria, progressively worsening fatigue, and poor appetite, even after the coronavirus disease 2019 antigen test returned negative. Her urinalysis showed positive proteinuria and hematuria. Her serum creatinine levels increased rapidly. Her anti-phospholipase A2 receptor antibody was borderline positive. Anti-glomerular basement membrane disease was diagnosed with high anti-glomerular basement membrane antibody titer. She responded well to corticosteroids, cyclophosphamide, and plasmapheresis. We further reviewed several cases of concurrent anti-glomerular basement membrane disease and membranous nephropathy. Phospholipase A2 receptor positivity was not rare in these patients, and their renal outcome was not optimistic. Thus, when the clinical manifestation changes in patients with pathologically confirmed glomerular disease, superimposition on other disease should be considered.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251335843"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12046159/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}