Journal of International Medical Research最新文献

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Comparison of noninvasive and intermittent positive pressure ventilation in treating extremely premature and extremely low birth weight infants. 无创和间歇正压通气治疗极早产儿和极低出生体重儿的比较。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241287740
Huifen Chen, Ming Zhang, Xingyu Bai, Shuang Zheng, Dawei Wei, Mengbin Zhang, Yanxia Qiao
{"title":"Comparison of noninvasive and intermittent positive pressure ventilation in treating extremely premature and extremely low birth weight infants.","authors":"Huifen Chen, Ming Zhang, Xingyu Bai, Shuang Zheng, Dawei Wei, Mengbin Zhang, Yanxia Qiao","doi":"10.1177/03000605241287740","DOIUrl":"10.1177/03000605241287740","url":null,"abstract":"<p><strong>Objective: </strong>We compared the application value of noninvasive positive pressure ventilation (NIPPV) and intermittent positive pressure ventilation (IPPV) in the treatment of very premature infants and extremely low birth weight infants.</p><p><strong>Methods: </strong>Multivariate logistic regression analysis was used to identify factors influencing the transition from noninvasive to invasive ventilation in this infant cohort.</p><p><strong>Results: </strong>Among extremely preterm infants, 83.3% with gestational age <25 weeks transitioned from noninvasive to invasive ventilation, as did 80.6% of those with birth weight <1000 grams. Multivariate analysis indicated that gestational age <25 weeks, birth weight <1000 grams, and Apgar score ≤7 were significant factors affecting the likelihood of transitioning to invasive ventilation. The survival rate at discharge was 94% for the NIPPV group compared with 89% for the IPPV group. The NIPPV group demonstrated significantly lower rates of complications, shorter weaning times, and reduced lengths of hospital stay compared with the IPPV group.</p><p><strong>Conclusions: </strong>Both NIPPV and IPPV effectively improved oxygenation and ventilation in extremely preterm infants. However, NIPPV showed significant advantages in reducing complications, shortening weaning time, and decreasing the hospital stay duration. Prioritizing the use of NIPPV may enhance treatment outcomes and survival quality, providing evidence-based support for clinical practice.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529657/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142502138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Progressive bone pain caused by a phosphaturic mesenchymal tumor in the left femur: a case report and literature review. 左股骨磷质间充质肿瘤引起的进行性骨痛:病例报告和文献综述。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241285540
Jianfei Yan, Jiangle Jiang, Xiaoguang Wu, Liuying Zhou
{"title":"Progressive bone pain caused by a phosphaturic mesenchymal tumor in the left femur: a case report and literature review.","authors":"Jianfei Yan, Jiangle Jiang, Xiaoguang Wu, Liuying Zhou","doi":"10.1177/03000605241285540","DOIUrl":"10.1177/03000605241285540","url":null,"abstract":"<p><p>Phosphaturic mesenchymal tumors (PMTs) are extremely rare mesenchymal tumors of soft tissue and bone that cause tumor-induced osteomalacia (TIO). Some of these tumors are completely asymptomatic and may grow undetected unless they become large enough to cause pain or discomfort. This type of tumor is crucial to diagnose in patients being treated for phosphate metabolism disorders and are a rare reason why patients seek medical help owing to pain. Here, we report the details of a patient with progressive bone pain caused by a PMT originating in the left femur.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11497532/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Systematic review of ultrasound-guided central venous catheter placement-related complications in neonates and infants aged <12 months. 超声引导下新生儿和 12 个月以下婴儿中心静脉导管置入相关并发症的系统性回顾。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241287168
Yu Cui, Yu Wang, Tianqing Gong, Qinghua Huang, Qian-Qian Zhang
{"title":"Systematic review of ultrasound-guided central venous catheter placement-related complications in neonates and infants aged <12 months.","authors":"Yu Cui, Yu Wang, Tianqing Gong, Qinghua Huang, Qian-Qian Zhang","doi":"10.1177/03000605241287168","DOIUrl":"10.1177/03000605241287168","url":null,"abstract":"<p><strong>Objective: </strong>Although ultrasound can be considered an assistant method, successful placement of a central venous catheter (CVC) in infants is still challenging. The incidence of CVC placement-related complications is still high. Therefore, this systematic review aimed to synthesize evidence to assess the effects of ultrasound-guided CVC placement on adverse outcomes in infants and neonates aged <12 months.</p><p><strong>Methods: </strong>PubMed, Ovid, EMBASE, and the Cochrane Library were searched to identify potentially relevant studies. The main outcome was the incidence of adverse events, which included inadvertent arterial puncture, hematoma, pneumothorax and hemothorax, catheter kinking, threading, and malpositioning problems, venous thrombosis, catheter-related infection, phlebitis, and cardiac tamponade.</p><p><strong>Results: </strong>Eleven studies involving 2097 patients were included in the final analysis. The odds of inadvertent arterial puncture, and catheter kinking, threading, and malpositioning problems were lower in the ultrasound group than in the control group. No significant difference was detected in the incidence of hematoma or venous thrombosis between the control and ultrasound groups. Other complications, such as pneumothorax, hemothorax, phlebitis, and cardiac tamponade, rarely occurred.</p><p><strong>Conclusion: </strong>Ultrasound-guided CVC placement can improve the safety of punctures in neonates and infants. CVC punctures should be guided in real-time by ultrasound.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11489976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467541","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of coastal and island geographic environments on patients with acute ischemic stroke in southeastern China. 沿海和海岛地理环境对中国东南部急性缺血性脑卒中患者的影响。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241285141
Xudong Lu, Xiaoci Lin, Yilei Shen, Mengmeng Hu, Daijun Zhu, Dongjuan Xu
{"title":"Effect of coastal and island geographic environments on patients with acute ischemic stroke in southeastern China.","authors":"Xudong Lu, Xiaoci Lin, Yilei Shen, Mengmeng Hu, Daijun Zhu, Dongjuan Xu","doi":"10.1177/03000605241285141","DOIUrl":"10.1177/03000605241285141","url":null,"abstract":"<p><strong>Objective: </strong>To analyze the geographic variation in characteristics and treatment processes of patients with acute ischemic stroke (AIS) in coastal, island, and inland regions.</p><p><strong>Methods: </strong>We conducted a retrospective, cross-sectional analysis of data from patients with AIS in southeastern China. We collected demographic and clinical information, including the time from stroke onset to treatment for those receiving reperfusion therapy, using a time-tracking table.</p><p><strong>Results: </strong>Among 8069 patients with AIS, 26.6% received reperfusion therapy, with a higher proportion undergoing endovascular therapy in maritime hospitals than in inland hospitals (14.2% vs. 6.7%). Maritime hospitals had a higher prevalence of atrial fibrillation (15.1% vs. 11.9%) and cardioembolism (17.2% vs. 13.6%) than inland hospitals. Patients in maritime hospitals had shorter in-hospital processing times than those in inland hospitals (39 vs. 46 minutes). Island hospitals showed different patterns, with a shorter time from stroke onset to emergency room arrival (80 vs. 120 minutes) but a longer in-hospital process time (51 vs. 36 minutes), than coastline hospitals.</p><p><strong>Conclusions: </strong>Our study suggests geographic variation in AIS characteristics and treatment processes across southeastern China, emphasizing the need for region-specific strategies. These findings are essential for tailoring public health policies and guidelines to improve stroke outcomes in various regions.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11472418/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142400491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Outcome and treatment of cesarean scar ectopic pregnancy under ultrasound-guided vacuum aspiration. 超声引导下真空吸引剖宫产疤痕异位妊娠的结果和治疗方法。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241281692
Naz Azad Abdullah
{"title":"Outcome and treatment of cesarean scar ectopic pregnancy under ultrasound-guided vacuum aspiration.","authors":"Naz Azad Abdullah","doi":"10.1177/03000605241281692","DOIUrl":"10.1177/03000605241281692","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to describe cases of cesarean scar pregnancies that were successfully treated with suction curettage under ultrasound guidance and their outcome.</p><p><strong>Methods: </strong>This retrospective, descriptive case-series study was performed on 17 patients diagnosed with cesarean scar ectopic pregnancy in Sulaimani Maternity Teaching Hospital from May 2022 to April 2023. The patients' sociodemographic and clinical data were collected. The patients were treated with suction curettage alone or in combination with local injection of methotrexate under ultrasound guidance.</p><p><strong>Results: </strong>Patients with a viable fetus (n = 4) received local intrinsic methotrexate injection into the gestational sac and suction curettage, while those in whom the fetus had died (n = 13) underwent only suction curettage. Five patients required intrauterine balloon insertion to stop bleeding without further treatment, and only three required a blood transfusion owing to severe bleeding.</p><p><strong>Conclusions: </strong>Cesarean scar ectopic pregnancy is a dangerous and complex disorder with an increasing occurrence in recent years. Accurate early diagnosis and effective management are essential to reduce maternal mortality and mortality of this type of pregnancy.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142348176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Branch retinal artery occlusion in a patient with COVID-19 infection: A case report. 一名感染 COVID-19 的患者视网膜分支动脉闭塞:病例报告。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241284931
Zhijian Jiang, Huiying Ji, Hui Zhang, Ziyi Dong, Jianhong Dong
{"title":"Branch retinal artery occlusion in a patient with COVID-19 infection: A case report.","authors":"Zhijian Jiang, Huiying Ji, Hui Zhang, Ziyi Dong, Jianhong Dong","doi":"10.1177/03000605241284931","DOIUrl":"10.1177/03000605241284931","url":null,"abstract":"<p><p>We report here, a case of branch retinal artery occlusion (BRAO) in the left eye of a 76-year-old man that involved three arteries which was considered to be related to a COVID-19 infection due to high levels of blood cytokines and coagulation factors. Although the patient had hypertension and atherosclerosis, his hypertension had been well controlled for the past five years by regular antihypertensive medication. Twenty-five days after starting treatment with anti-inflammatory, anticoagulant and conservative therapy, the patient's biomarkers of inflammation and coagulation returned to normal and his vision improved. However, some visual field defects remained and were probably a consequence of low oxygen saturation.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529667/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142348175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of ischaemia-modified albumin in the prognosis of acute pancreatitis and its correlation with the NF-κB-mediated inflammatory response. 缺血修饰白蛋白在急性胰腺炎预后中的作用及其与 NF-κB 介导的炎症反应的相关性。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241287163
Cheng Geng, Junxiang Zhang, Shixing Wu, Bolin Zhang, Xinxin Tian, Tigu A, Hongde Su, Xinjian Xu
{"title":"The role of ischaemia-modified albumin in the prognosis of acute pancreatitis and its correlation with the NF-<b>κ</b>B-mediated inflammatory response.","authors":"Cheng Geng, Junxiang Zhang, Shixing Wu, Bolin Zhang, Xinxin Tian, Tigu A, Hongde Su, Xinjian Xu","doi":"10.1177/03000605241287163","DOIUrl":"10.1177/03000605241287163","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the correlation between the serum levels of ischaemia-modified albumin (IMA) and disease severity in rats with acute pancreatitis (AP).</p><p><strong>Methods: </strong>A rat AP model was established and blood samples from each group were analysed at different time points. After the experiment, the pancreatic tissues of the rats were collected for pathological examination and the measurement of protein levels of NF-κB and NF-κB p65. Serum levels of amylase (α-AMY), tumour necrosis factor-α (TNF-α), interleukin (IL)-6 and IL-8 were also compared between groups of rats.</p><p><strong>Results: </strong>The serum IMA concentration in the severe acute pancreatitis (SAP) group was greater than that in the mild acute pancreatitis (MAP) group. The levels of the NF-κB and NF-κB p65 proteins were increased in the MAP and SAP groups in a time-dependent manner. α-AMY, TNF-α and IL-6 were increased at all time points in the MAP and SAP groups. The increases were greatest at 24 h in the SAP group. In terms of pathological changes in the pancreas, renal and lung tissues, the damage in the SAP group was more obvious than that in the MAP group.</p><p><strong>Conclusions: </strong>Serum IMA level was associated with inflammatory markers and NF-κB p65 in rats with AP.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence and risk factors of low bone mineral density in Chinese Han male patients with alcohol dependence. 中国汉族男性酒精依赖症患者骨矿物质密度低的患病率和风险因素。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241291759
Yu Liu, Qianhui Xia, Zenghui Ding, Lina Gu, Yayun Xu, Yongmei Wang, Xulai Zhang
{"title":"Prevalence and risk factors of low bone mineral density in Chinese Han male patients with alcohol dependence.","authors":"Yu Liu, Qianhui Xia, Zenghui Ding, Lina Gu, Yayun Xu, Yongmei Wang, Xulai Zhang","doi":"10.1177/03000605241291759","DOIUrl":"10.1177/03000605241291759","url":null,"abstract":"<p><strong>Objective: </strong>To investigate the prevalence of low bone mineral density (BMD) along with its possible risk factors in male Han Chinese patients with alcohol dependence (AD).</p><p><strong>Methods: </strong>This retrospective, cross-sectional study included male patients with AD, classified into normal and low BMD groups according to bone densitometry T scores. Demographic and alcohol-related data, and routine laboratory parameters were compared between the two groups. Binary logistic regression analysis was employed to evaluate risk factors associated with low BMD, and correlations between the T-score and demographic, alcohol-related, and routine laboratory data were evaluated.</p><p><strong>Results: </strong>Among a total of 107 patients with AD included in the study, the prevalence of low BMD was 70.09% (75/107). Patients with low BMD were older, consumed more alcohol daily, and had higher lactate dehydrogenase (LDH) and lower Ca<sup>2+</sup> levels than patients with normal BMD. Regression analysis revealed that increased daily alcohol intake, low serum Ca<sup>2+</sup> levels, high serum LDH levels, and comorbid hypertension was related to low BMD in patients with AD. Further correlation analysis revealed a positive association between T-score and serum Ca<sup>2+</sup> levels.</p><p><strong>Conclusion: </strong>Increased daily alcohol intake, low serum Ca<sup>2+</sup> levels, high serum LDH levels, and comorbid hypertension may be risk factors for low BMD.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11529730/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of COVID-19 infection in patients with NSCLC receiving EGFR-TKI targeted therapy during the first wave in China. 中国第一波接受 EGFR-TKI 靶向治疗的 NSCLC 患者感染 COVID-19 的风险。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241281907
Peng Huang, Ling-Ming Liao, Jia-Li Zhao, Chen Luo, Yan-Ling Yi, Yu Chen, Long Huang
{"title":"Risk of COVID-19 infection in patients with NSCLC receiving EGFR-TKI targeted therapy during the first wave in China.","authors":"Peng Huang, Ling-Ming Liao, Jia-Li Zhao, Chen Luo, Yan-Ling Yi, Yu Chen, Long Huang","doi":"10.1177/03000605241281907","DOIUrl":"https://doi.org/10.1177/03000605241281907","url":null,"abstract":"<p><strong>Objective: </strong>We examined the factors influencing hospitalization and prognosis among patients with non-small cell lung cancer receiving epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) targeted therapy during the first wave of the coronavirus disease 2019 (COVID-19) pandemic.</p><p><strong>Methods: </strong>In total, 267 patients diagnosed with NSCLC who were receiving treatment with third-generation EGFR-TKIs were included in our retrospective study. Data on patients' demographics, clinical characteristics, and survival were collected and analyzed.</p><p><strong>Results: </strong>Over a mean follow-up of 18 months, 80.5% (215/267) of the patients contracted COVID-19, and 12.6% (27/215) of these patients were hospitalized for COVID-19 treatment. Vaccinated patients, those with body mass index (BMI) ≥22.3 kg/m<sup>2</sup>, and those with no comorbidities had lower rates of infection and hospitalization than unvaccinated patients, those with BMI <22.3 kg/m<sup>2</sup>, and those with comorbidities, respectively. Continued NSCLC treatment in patients with COVID-19 was identified as a risk factor for patient survival.</p><p><strong>Conclusions: </strong>NSCLC treatment can be continued for patients who received COVID-19 vaccines, those with higher BMI, and those without comorbidities during the COVID-19 epidemic, but treatment interruption might be required for patients during the active phase of infection.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11467978/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142467539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Improving patient outcomes in acute and subacute stroke using a wearable device-assisted rehabilitation system: a randomized controlled trial. 利用可穿戴设备辅助康复系统改善急性和亚急性中风患者的治疗效果:随机对照试验。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-10-01 DOI: 10.1177/03000605241281425
Hsin-Ju Ho, Li-Ching Wu, Eric Hsiao-Kung Wu, Shu-Fang Lee, Te-Hsiu Lee, Sheng-Hua Chiang, Chun-Hsiung Chen, Hui-Yu Chen, Shiuan-Jia Pan, Yu-Wei Chen
{"title":"Improving patient outcomes in acute and subacute stroke using a wearable device-assisted rehabilitation system: a randomized controlled trial.","authors":"Hsin-Ju Ho, Li-Ching Wu, Eric Hsiao-Kung Wu, Shu-Fang Lee, Te-Hsiu Lee, Sheng-Hua Chiang, Chun-Hsiung Chen, Hui-Yu Chen, Shiuan-Jia Pan, Yu-Wei Chen","doi":"10.1177/03000605241281425","DOIUrl":"10.1177/03000605241281425","url":null,"abstract":"<p><strong>Objective: </strong>Multidisciplinary rehabilitation facilitates post-stroke functional recovery, but is associated with resource and accessibility barriers. This study evaluated the combination of a wearable device-assisted system (WEAR) and conventional therapy for post-stroke rehabilitation.</p><p><strong>Methods: </strong>This randomized, controlled, parallel group, clinical trial was conducted at two rehabilitation centers. A WEAR system was developed featuring sensors and application program-embedded smartphones. Stroke patients within 12 weeks of onset and modified Rankin Scale (mRS) scores of 2 to 4 were randomized into a wearable group (WG, WEAR + conventional rehabilitation) or control group (CG, conventional rehabilitation) for 90 days. The primary outcome was mRS score changes within 90 days.</p><p><strong>Results: </strong>Among 127 stroke patients enrolled (76 men [59.8%]; mean age: 57.5 years), 63 and 64 patients were randomized to WG and CG, respectively. Both groups showed significant improvements in mRS scores. Between-group repeated measures analysis adjusted for sex, age and number of rehabilitation sessions showed greater improvement in mRS scores within 90 days in the WG than in the CG (estimate: 0.73).</p><p><strong>Conclusions: </strong>This combined WEAR and conventional rehabilitation approach may improve post-stroke functional recovery compared with conventional rehabilitation alone. The WEAR system permits remote monitoring and recording of rehabilitation in various settings.This clinical trial was retrospectively registered at www.clinicaltrials.gov with the Unique Identifier NCT04997408.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11468635/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142486254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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