Journal of International Medical Research最新文献_第4页

Posterior reversible encephalopathy syndrome in adult acute post-streptococcal glomerulonephritis.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251318851

Qiuping Han, Linlin Zhu

引用次数: 0

Embolization for haemomediastinum due to spontaneous rupture of oesophageal branch arising from an unusual origin (inferior thyroidal artery) after vomiting: a case report.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605241290716

Jin Suk Lee, Eic Ju Lim, Min Jai Cho, Yook Kim

引用次数: 0

Role of the CHA₂DS₂-VASc score in predicting hospital stay and 90-day readmission among patients with atrial fibrillation in Syria.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251314807

Ibrahim Antoun, Alamer Alkhayer, Alkassem Alkhayer, Yaman Mahfoud, Ahmed Kotb, Riyaz Somani, G André Ng, Mustafa Zakkar

{"title":"Role of the CHA2DS2-VASc score in predicting hospital stay and 90-day readmission among patients with atrial fibrillation in Syria.","authors":"Ibrahim Antoun, Alamer Alkhayer, Alkassem Alkhayer, Yaman Mahfoud, Ahmed Kotb, Riyaz Somani, G André Ng, Mustafa Zakkar","doi":"10.1177/03000605251314807","DOIUrl":"10.1177/03000605251314807","url":null,"abstract":"Objectives: We assessed the CHA2DS2-VASc score for predicting hospital readmission risk and length of stay (LOS) in patients admitted with primary atrial fibrillation (AF).Methods: This retrospective cohort study included patients with index admission for AF to Latakia's tertiary center (May 2021-November 2023). Patients were followed 90 days to assess readmission. CHA2DS2-VASc was correlated with 90-day readmission, inpatient all-cause mortality, and LOS during index admission.Results: In total, 717 patients were included; 320 (45%) were readmitted to the hospital within 90 days (58% men, 65% aged <65 years). Inpatient mortality was 4%; the median LOS was 2 days. There was an increase in the incident rate ratio (IRR) of LOS starting from a CHA2DS2-VASc of 2 (IRR: 2, 95% confidence interval [CI]: 1.7-2.2) to a score of >6 (IRR: 5, 95% CI: 1.8-10.7), compared with a score of 0. There was an incremental increase in the hazard ratio (HR) of readmission from a score of 1 (HR: 2.3, 95% CI: 1.3-4.1) to a score of >6 (HR: 41, 95% CI: 31-72) compared with a CHA2DS2-VASc of 0.Conclusion: CHA2DS2-VASc could predict 90-day hospital readmission and LOS during the index admission in patients admitted with primary AF.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251314807"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143374200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An isolated congenital absence of right pulmonary artery associated with coronary and multiple systemic collaterals: A case report and literature review.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251320763

Rola K Bsharat, Daleen Shehadeh, Raneen W Atatrah, Mahmoud R Manasra, Baha Alhadad, Bajis Amr

{"title":"An isolated congenital absence of right pulmonary artery associated with coronary and multiple systemic collaterals: A case report and literature review.","authors":"Rola K Bsharat, Daleen Shehadeh, Raneen W Atatrah, Mahmoud R Manasra, Baha Alhadad, Bajis Amr","doi":"10.1177/03000605251320763","DOIUrl":"10.1177/03000605251320763","url":null,"abstract":"Unilateral pulmonary artery agenesis (UPAA) is the complete absence of either the right or left pulmonary artery. It is a rare congenital malformation, usually associated with other cardiac defects; however, in some cases, it may occur as an isolated lesion, typically affecting the right side. Patients with isolated right pulmonary artery agenesis are often diagnosed incidentally on chest radiographs in adulthood. Rare cases are associated with multiple systemic collaterals that supply the affected lung. We report the case of a 69-year-old man with the absence of a right pulmonary artery, arterial supply to the right lung from the celiac trunk, and communication of the collaterals with a marginal branch arising from the right coronary artery. UPAA is a rare congenital anomaly that may present with nonspecific symptoms, such as dyspnea and recurrent chest infections. Clinicians should consider UPAA in the differential diagnosis of respiratory symptoms, particularly in adult patients with unexplained symptoms.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251320763"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11846099/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A rare case of acrokeratosis paraneoplastica (Bazex syndrome) and a literature review.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251317998

Xiaoyan Zhang

引用次数: 0

Preoperative digital design in artificial total hip arthroplasty for patients with Crowe type III and IV developmental dysplasia of the hip: A case series.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251320223

Jinxin Zheng, Wei Chen, Yancheng Xiu, Shuzhang Guo

{"title":"Preoperative digital design in artificial total hip arthroplasty for patients with Crowe type III and IV developmental dysplasia of the hip: A case series.","authors":"Jinxin Zheng, Wei Chen, Yancheng Xiu, Shuzhang Guo","doi":"10.1177/03000605251320223","DOIUrl":"10.1177/03000605251320223","url":null,"abstract":"Successful complete artificial total hip arthroplasty for patients with Crowe type III or IV developmental dysplasia of the hip is challenging in clinical practice. This study aimed to explore the accuracy and effectiveness of preoperative digital design for patients with Crowe type III or IV developmental dysplasia of the hip. This case series study included patients with osteoarthritis secondary to developmental dysplasia of the hip who did not respond to conservative treatment and subsequently required total hip arthroplasty in Tianjin Third Central Hospital between January 2018 and February 2020. A total of 20 patients (5 males and 15 females) were enrolled, of whom 12 presented with Crowe type III and 8 with Crowe type IV developmental dysplasia of the hip. Total hip arthroplasty for each patient was successful. The implanted acetabular cups were one size (2 mm) smaller than the preoperatively designed size in four patients, and the implanted femoral stem prosthesis was one size (1 mm) larger than the preoperatively designed size in four patients with type IV DDH. The Harris scores differed significantly between preoperative and postoperative measurements (58.6 vs. 94.4; P = 0.016). No infection or joint dislocation was observed. Preoperative digital modeling may be used to predict the size of prosthesis required and location for implantation in patients undergoing total hip arthroplasty.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"271678X251322032"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866356/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143515755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Causal relationship between circulating inflammatory cytokines and the risk of hernia: a bidirectional Mendelian randomization study.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251315923

Yaqin Qi, Changjiu Li, Xingyue Gao, Fangjie Zhang

{"title":"Causal relationship between circulating inflammatory cytokines and the risk of hernia: a bidirectional Mendelian randomization study.","authors":"Yaqin Qi, Changjiu Li, Xingyue Gao, Fangjie Zhang","doi":"10.1177/03000605251315923","DOIUrl":"10.1177/03000605251315923","url":null,"abstract":"Objective: Observational studies suggest a link between hernia and inflammatory cytokines, but randomized trials are limited by ethical and cost constraints. In this study, we used bidirectional Mendelian randomization (MR) to investigate the causal relationship between inflammatory cytokines and five types of hernia, aiming to inform preventive and therapeutic strategies.Methods: We selected 41 inflammatory factors and five types of hernia as instrumental variables, using data from the IEU Open GWAS database including individuals of European descent. The primary analysis used the inverse variance weighted method with false discovery rate (FDR) adjustment. Additional MR methods and sensitivity analyses ensured robustness. Reverse MR was used to assess potential reverse causality.Results: After FDR adjustment, stem cell growth factor beta (SCGFb) was causally associated with diaphragmatic hernia (odds ratio = 0.884, 95% confidence interval: 0.819-0.955). Reverse MR indicated that diaphragmatic hernia may increase interferon gamma-induced protein 10 (IP10) and monokine induced by interferon-gamma (MIG), and ventral hernia may elevate macrophage inflammatory protein-1b (MIP1b). Sensitivity analyses confirmed robustness.Conclusion: SCGFb may protect against diaphragmatic hernia, and IP10, MIG, and MIP1b are involved in hernia development, suggesting the therapeutic potential of targeting these cytokines. Further studies are needed.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251315923"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Relationship between plasma polymyxin B concentrations and acute kidney injury in critically ill elderly patients: Findings from a prospective study.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251320733

Changyun Zhao, Wenchao Mao, Feifei Ye, Kailun Cai, Shijin Gong, Cong Ye, Yihua Yu

{"title":"Relationship between plasma polymyxin B concentrations and acute kidney injury in critically ill elderly patients: Findings from a prospective study.","authors":"Changyun Zhao, Wenchao Mao, Feifei Ye, Kailun Cai, Shijin Gong, Cong Ye, Yihua Yu","doi":"10.1177/03000605251320733","DOIUrl":"10.1177/03000605251320733","url":null,"abstract":"Objective: The objective of this study was to determine the relationship between the plasma polymyxin B concentration and renal function in elderly patients.Methods: This prospective, case-control, observational study included elderly patients who received polymyxin B therapy and were divided into an acute kidney injury (AKI) group and a non-AKI group based on their renal function. We monitored the pharmacokinetics and pharmacodynamics of polymyxin B, including the minimum plasma concentration (Cmin), mean blood drug concentration at steady state (Css,avg), and area under the concentration-time curve across 24 h at steady state (AUCss,24h) in both study groups. The plasma polymyxin concentration was determined using high-performance liquid chromatography-tandem mass spectrometry.Results: The loading doses, Cmin, Css,avg, and AUCss,24h were significantly higher in the AKI group than in the non-AKI group (p < 0.05). Receiver-operating characteristic curve analysis showed that the optimal cutoff values for predicting AKI were 2.94 mg/L for Cmin, 4.14 mg/L for Css,avg, and 99.35 mg·h/L for AUCss,24h, with corresponding sensitivities and specificities ranging from 78.57% to 82.14%.Conclusion: Monitoring plasma polymyxin B concentrations is essential in elderly patients. Keeping the Cmin below 2.94 mg/L, the Css,avg below 4.14 mg/L, and the AUCss,24h below 99.35 mg h/L may help prevent AKI in this population.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251320733"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831629/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433329","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Spatial clusters and temporal trends of cutaneous malignant melanoma mortality in Spain.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251319609

Lucía Cayuela, José-Juan Pereyra-Rodriguez, Juan-Carlos Hernández-Rodríguez, Aurelio Cayuela

{"title":"Spatial clusters and temporal trends of cutaneous malignant melanoma mortality in Spain.","authors":"Lucía Cayuela, José-Juan Pereyra-Rodriguez, Juan-Carlos Hernández-Rodríguez, Aurelio Cayuela","doi":"10.1177/03000605251319609","DOIUrl":"10.1177/03000605251319609","url":null,"abstract":"Objective: To analyse time trends in mortality due to cutaneous malignant melanoma (CMM) in Spain between 1980 and 2020, and to identify possible spatial clusters of provinces with an excess risk of CMM mortality during the period 2011-2020.Methods: Joinpoint regression models were used to assess temporal trends in data from the Spanish National Institute of Statistics. Crude rates, standardized mortality ratio (SMR), smoothed relative risk (RR), and posterior probabilities (PP) of RR >1 during the period 2011-2020 were calculated. The Global Moran I index was used to assess global spatial autocorrelation.Results: Two time-periods were detected in women: a significant increase during 1980-1994 (annual percent change [APC], 6.5% per year) and rate stabilization during 1994-2020 (nonsignificant APC, -0.17%). A similar pattern was observed in men, with three periods comprising a significant increase during 1980-1985 (APC, 16.59%), a slowing of the increase during 1985-1998 (APC, 4.40%), and stabilization during 1998-2020 (nonsignificant APC, 0.37%). Spatial analysis showed greater spatial heterogeneity with an east-north pattern in men compared with the pattern in women, which tended to be concentrated in north-western areas.Conclusion: Mortality rates associated with CMM in Spain have remained stable in recent years. There were provincial clusters that exhibited an excess risk of mortality from CMM, with different patterns according to sex.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251319609"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11831644/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143433330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The dose-response relationship and gender differences of serum uric acid with total cholesterol: a cross-sectional study.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251318203

Leilei Guo, Lina Cai, Li Hu, Yueshan Zhou

{"title":"The dose-response relationship and gender differences of serum uric acid with total cholesterol: a cross-sectional study.","authors":"Leilei Guo, Lina Cai, Li Hu, Yueshan Zhou","doi":"10.1177/03000605251318203","DOIUrl":"https://doi.org/10.1177/03000605251318203","url":null,"abstract":"Objective: To explore the dose-response relationship and gender differences between serum uric acid (SUA) and total cholesterol (TC) in Chinese individuals.Methods: This cross-sectional study included secondary data of Chinese adults, collected between 2010 and 2018. The exposure variable was SUA, the outcome variable was TC, and participants were split into five quantiles by SUA levels (Q1 [men, ≤283; women, ≤223] to Q5 [men, ≥416; women, ≥332]). Covariates included age, gender, laboratory and examination information. Multivariable linear regression and subgroup analysis were performed to examine the independent association between SUA and TC. Smooth curve fitting and threshold effect analysis was employed to assess potential non-linear relationships. Additionally, a sensitivity analysis was conducted to validate the robustness of the findings.Results: The analysis included 6119 participants, of whom, 4078 (66.6%) were female, with a mean age of 63.7 years. After adjusting for potential confounders, SUA showed a significant association with TC in both men (β = 0.09; 95% confidence interval [CI] 0.05, 0.14) and women (β = 0.13; 95% CI 0.10, 0.17). The Q5 group exhibited higher TC levels than the Q1 group in both men (β = 0.26; 95% CI 0.16, 0.37) and women (β = 0.25, 95% CI 0.17, 0.32). In women, there was an inverted L-shaped relationship between SUA and TC with an inflection point at 359.962 μmol/L, whereas a linear relationship was exhibited in men. Subgroup analysis showed no significant interactions in men. Sensitivity analyses confirmed the robustness of the findings.Conclusions: Significant sex differences and dose-response relationships exist between SUA and TC in the Chinese population. The study may provide new insights into cholesterol management.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251318203"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143408707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0