{"title":"Study on the use of intravascular ultrasound-guided coronary intravascular lithotripsy compared with rotational atherectomy: a single-center, retrospective study.","authors":"Ben Li, Jiaxing Li, Guangxin Hu, Shichang Zhang, Yongkang Ren, Mingyang Li, Yinping Li, Shaobin Jia","doi":"10.1177/03000605241305369","DOIUrl":"10.1177/03000605241305369","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to compare the efficacy and safety of intravascular ultrasound (IVUS)-guided coronary intravascular lithotripsy and rotational atherectomy in treating severe coronary artery calcification.</p><p><strong>Methods: </strong>A retrospective analysis of 60 patients who underwent percutaneous coronary intervention at the General Hospital of Ningxia Medical University from October 2022 to August 2023 was conducted. The patients were divided into two groups: 30 received IVUS-guided coronary intravascular lithotripsy and 30 underwent IVUS-guided rotational atherectomy. The primary endpoints comprised angiographic thrombolysis in myocardial infarction III flow and <30% stenosis post-percutaneous coronary intervention, and IVUS metrics, such as >80% stent expansion, avoiding high plaque burden or lipid-rich plaques, minimizing malapposition <0.4 mm/1 mm, and preventing tissue prolapse and dissection. Safety was assessed by complications and 1- and 6-month postoperative major adverse cardiovascular event rates.</p><p><strong>Results: </strong>The primary endpoint was achieved in both groups. The treatment efficacy was 100% in all cases. At 1 and 6 months post-procedure, there was no significant difference in major adverse cardiovascular events, acute myocardial infarction, or stent thrombosis between the two groups.</p><p><strong>Conclusion: </strong>IVUS-guided coronary intravascular lithotripsy is a safe and effective alternative to rotational atherectomy, potentially reducing certain complications.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241305369"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682570/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chun Yang, Xia Chi, Yan Wang, Cuiping Zhang, Ran Zhou, Xuemei Jia, Fengchang Qiao, Zhengfeng Xu
{"title":"Subgroup analysis of imaging scans, invasive examinations and prognosis in mild-to-moderate isolated foetal cerebral ventriculomegaly: a retrospective study in China.","authors":"Chun Yang, Xia Chi, Yan Wang, Cuiping Zhang, Ran Zhou, Xuemei Jia, Fengchang Qiao, Zhengfeng Xu","doi":"10.1177/03000605241301879","DOIUrl":"10.1177/03000605241301879","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to analyse the causes of foetal mild-to-moderate isolated ventriculomegaly (IVM) and to evaluate the prognosis of neurological development in surviving children in different subgroups.</p><p><strong>Methods: </strong>We retrospectively studied mild-to-moderate IVM diagnosed by prenatal ultrasound scans in different subgroups according to the laterality of IVM, the degree of IVM and foetal sex independently. The results of foetal chromosomal microarray analysis, virological tests of umbilical cord blood or amniotic fluid, foetal magnetic resonance imaging and ultrasound were collected. Long-term follow-up was performed to assess the neurodevelopment of children within 66 months through telephone interviews and/or the Ages and Stages Questionnaire-3.</p><p><strong>Results: </strong>The moderate group showed more chromosomal abnormalities (16.2% vs. 4.1%) and greater structural anomalies in the brain (31.8% vs. 7.5%) than the mild group. Female foetuses showed more structural anomalies than male foetuses (25.0% vs. 7.2%). However, an adverse prognosis of children was not different across the different subgroups.</p><p><strong>Conclusion: </strong>Moderate IVM may be more strongly associated with chromosomal aberrations and structural malformations than mild IVM. However, the adverse prognosis of children was similar between the different subgroups analysed.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241301879"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626665/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Deborah K Becker, Meike Röder, Johannes Wagenhäuser, Sebastian Eichberger, Monika Herten, Marcel Dudda
{"title":"Necrotizing fasciitis that led to unexpected and fulminant deterioration in less than 24 hours: a case report.","authors":"Deborah K Becker, Meike Röder, Johannes Wagenhäuser, Sebastian Eichberger, Monika Herten, Marcel Dudda","doi":"10.1177/03000605241290480","DOIUrl":"10.1177/03000605241290480","url":null,"abstract":"<p><p>Necrotizing fasciitis (NF) is a rapidly progressing condition with a high mortality rate. The poor prognosis is often due to delayed diagnosis, which is typically made clinically or radiologically. This case report highlights a rare instance of fulminant NF with an atypical presentation-no initial clinical signs and an unusual radiological appearance. Both the localization and microbiological findings (non-resistant <i>Klebsiella pneumoniae</i>) were uncommon for NF. The patient presented with no suspicious skin changes, pain, or medical history indicative of NF. A computed tomography scan revealed entrapped air, a pathognomonic sign of NF; however, the air was predominantly located in the abdomen, leading to an initial suspicion of hollow organ perforation because this is an unusual location for NF. Subsequently, NF was suspected based on the computed tomography findings combined with laboratory results. Despite prompt surgical intervention and broad-spectrum antibiotic therapy, the patient died of multi-organ failure within 16 hours. This case underscores the importance of recognizing the subtle and varied presentations of NF and using tools such as the Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) score. Healthcare providers must maintain a high index of suspicion for NF, even when clinical, radiological, and laboratory findings seem inconspicuous.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241290480"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622346/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"MINOCA as the result of coronary artery aneurysm thrombosis.","authors":"Oksana Rokyta","doi":"10.1177/03000605241301859","DOIUrl":"10.1177/03000605241301859","url":null,"abstract":"<p><p>Myocardial infarction (MI) can be caused by many factors. In addition to the typical obstruction or stenosis of the coronary arteries, there is heterogenic MI with non-obstructive coronary arteries (MINOCA). A rare cause of MINOCA is the thrombosis of a coronary artery aneurysm (CAA). This current case report describes a male patient with CAA thrombosis as the cause of MINOCA following surgery for a mucoepidermoid carcinoma. The patient underwent angiography that identified three CAAs that were located as follows: (i) in the proximal part of the left anterior descending artery (5.55 mm); (ii) in the distal part of the circumflex artery (8.05 mm); and (iii) in the distal part of the right coronary artery (6.61 mm). Thrombotic masses were identified within all three structures. The patient received balloon angioplasties without stent implanting and recovered well. The patient was also notable for the presence of two brain artery aneurysms that were the cause of the previous strokes that he had experienced. This case report also reviews the literature in order to: (i) summarize the aetiological factors and clinical manifestations of CAA; (ii) discuss the diagnostic methods for CAA; (iii) describe the medical and surgical management of CAA; and (iv) assess the prognosis of this rare clinical event.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241301859"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Weiting Chen, Min Tang, Yaling Jin, Lihui Chen, Jiuzhou Lin, Xuelin Yang
{"title":"Automated ultrasonographic pupillary assessment: a new neuro-ophthalmological assessment tool.","authors":"Weiting Chen, Min Tang, Yaling Jin, Lihui Chen, Jiuzhou Lin, Xuelin Yang","doi":"10.1177/03000605241299927","DOIUrl":"10.1177/03000605241299927","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate correlations between ultrasonographic pupillary assessment (UPA) and automated UPA in neurocritical patients.</p><p><strong>Methods: </strong>This was a prospective, observational study of 20 adult patients admitted to the intensive care unit with neurological pathology. Between UPA and automated UPA, 40 pupillary measurements were made. The time required to conduct UPA and automated UPA on a single patient was consistently < 3 minutes. Automated UPA required a markedly shorter operational time than UPA.</p><p><strong>Results: </strong>There were strong positive associations between UPA and automated UPA measurements, with the following correlations: right eye at rest, <i>r</i> = 0.9973; left eye at rest, <i>r</i> = 0.9989; right eye post-pupillary light response, <i>r</i> = 0.9975; left eye post-pupillary light response, <i>r</i> = 0.9955. Bland-Altman analyses confirmed the strong agreement between the two methods under both conditions, with most measurements falling within the limits of agreement. Both the right and left pupillary diameters at rest demonstrated consistency, and the post-pupillary light response measurements for both eyes indicated good agreement, with a few outliers.</p><p><strong>Conclusions: </strong>Automated UPA was strongly correlated with UPA in neurocritical patients. Automated UPA is a rapid, feasible, and noninvasive method that enables the precise evaluation of pupillary size and light response.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241299927"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Chao Peng, Weihao Wang, Jiajun Chen, Shouhua Pan, Gang Xu, Mengyao Li, Lulu Zhang, Yulei Li, Keyuan Zhao, Jing Jin
{"title":"Long-term survival of a kidney transplant patient with advanced renal cancer after combination therapy: a case report and literature review.","authors":"Chao Peng, Weihao Wang, Jiajun Chen, Shouhua Pan, Gang Xu, Mengyao Li, Lulu Zhang, Yulei Li, Keyuan Zhao, Jing Jin","doi":"10.1177/03000605241304640","DOIUrl":"10.1177/03000605241304640","url":null,"abstract":"<p><p><i>De novo</i> renal transplant carcinoma, especially in the context of bilateral renal carcinoma, is rare and often presents as small, low-grade papillary renal cell carcinoma (RCC). There is currently no consensus or effective treatment for advanced metastatic RCC after kidney transplantation. A 40-year-old man developed <i>de novo</i> renal transplant carcinoma with venous thrombus and lung metastases 13 years after transplantation. The patient underwent cytoreductive nephrectomy followed by sequential treatment with tyrosine kinase inhibitors (TKI) and anti-PD-1 monoclonal antibodies. After 2 years, the patient showed excellent graft function with no evidence of cancer progression. Despite subsequent graft failure, the disease remained controlled for more than 2 years and the patient survived for more than 3 years, which was significantly longer than the typical survival of 10 to 20 months in patients with advanced kidney cancer. The results suggest that combining cytoreductive nephrectomy with TKI and anti-PD-1 therapy may significantly prolong survival in patients with renal allograft carcinoma.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241304640"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jie Zhang, Lin Zhou, Tao Liu, Yuhan Cheng, Yanling Dou
{"title":"Cerebral infarction presenting with bilateral sudden deafness as the primary symptom: a case report.","authors":"Jie Zhang, Lin Zhou, Tao Liu, Yuhan Cheng, Yanling Dou","doi":"10.1177/03000605241305483","DOIUrl":"10.1177/03000605241305483","url":null,"abstract":"<p><p>The current case report presents a rare occurrence of cerebral infarction with bilateral sudden deafness as the primary symptom. The patient was a 59-year-old man with hypertension who tested positive for new coronary antibodies and had a long history of smoking and alcohol consumption. Despite receiving treatment for sudden deafness, the patient's condition rapidly deteriorated and he was diagnosed with basilar artery occlusion and stenosis. The patient died 5 days after mechanical recanalization of the artery. Sudden binaural deafness is a rare clinical condition that may be a prodromal symptom of brainstem infarction. Early diagnosis and prompt treatment are essential for reducing mortality and disability.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241305483"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11672386/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142876878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Corrigendum to \"Positioning tezepelumab for patients with severe asthma: from evidence to unmet needs\".","authors":"","doi":"10.1177/03000605241306931","DOIUrl":"10.1177/03000605241306931","url":null,"abstract":"","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241306931"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142784641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Musculoskeletal ultrasonography versus conventional radiography: Correlation with DAS28 and MDHAQ scores in early rheumatoid arthritis.","authors":"Reem Hamdy A Mohammed, Hatem Alazizi, Asmaa Negm Eldin Taha, Seham Metawee","doi":"10.1177/03000605241306397","DOIUrl":"10.1177/03000605241306397","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the value of musculoskeletal ultrasound (MSUS) with conventional radiography in the detection of patients with early rheumatoid arthritis (RA) and to correlate the sonographic findings with disease activity, and functional disability scores.</p><p><strong>Methods: </strong>Patients >18 years of age with RA ≤2 years who satisfied the 2010 EULAR/ACR classification criteria for rheumatoid arthritis and disease activity score 28 (DAS28) >2.6, were enrolled. Plain radiographs and MSUS examinations were performed on 18 joints bilaterally. DAS28 and multi-dimensional health assessment questionnaire (MDHAQ/RAPID) scores were assessed.</p><p><strong>Results: </strong>Forty patients (35 women, 5 men), mean age 41 ± 12 years, and mean disease duration 11 ± 5 months, were included. In total, 720 joints were examined. The number of hand joints affected by erosions via MSUS was 3.28-fold the number detected by X-ray. Sonographic evidence of synovitis and active erosion significantly correlated with MDHAQ, DAS28 and inflammatory biomarkers.</p><p><strong>Conclusion: </strong>Joint sonography was superior to conventional radiography in early detection of structural joint damage and active disease in patients with early RA which correlated with disease activity and functional ability scores.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241306397"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jing-Rui Wang, Qi-Jun Yang, Bei Lu, Yang Cai, Jun-Jie Yin
{"title":"Primary hepatic epithelioid hemangioendothelioma: a case report.","authors":"Jing-Rui Wang, Qi-Jun Yang, Bei Lu, Yang Cai, Jun-Jie Yin","doi":"10.1177/03000605241306649","DOIUrl":"10.1177/03000605241306649","url":null,"abstract":"<p><p>Epithelioid hemangioendothelioma is a low-grade malignant tumor of vascular origin. The rarity of hepatic epithelioid hemangioendothelioma (HEHE) makes the diagnosis and treatment of this entity challenging. We report a case of a 69-year-old female patient who suffered from HEHE and complained of abdominal distension pain with dizziness and appetite loss for more than half a month. Enhanced computed tomography of the upper abdomen indicated multiple space-occupying lesions in the liver. The pathological results of color ultrasound puncture suggested HEHE. We performed transcatheter arterial chemoembolization and relevant examinations according to the patient's condition and their choice. We followed the patient for 5 years and found that she developed recurrent intrahepatic metastasis of the tumor. Computed tomography was performed again after 3 months of treatment with anlotinib and the tumor did not show any progression. HEHE is a relatively rare hepatic malignant tumor derived from vascular endothelial cells, with a low incidence, atypical clinical manifestations, and a difficult diagnosis that can only be confirmed with pathological results. Currently, appropriate treatment methods should be selected according to the specific conditions of the patient.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241306649"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}