Journal of International Medical Research最新文献_第3页

Automated ultrasonographic pupillary assessment: a new neuro-ophthalmological assessment tool.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241299927

Weiting Chen, Min Tang, Yaling Jin, Lihui Chen, Jiuzhou Lin, Xuelin Yang

{"title":"Automated ultrasonographic pupillary assessment: a new neuro-ophthalmological assessment tool.","authors":"Weiting Chen, Min Tang, Yaling Jin, Lihui Chen, Jiuzhou Lin, Xuelin Yang","doi":"10.1177/03000605241299927","DOIUrl":"10.1177/03000605241299927","url":null,"abstract":"Objective: To evaluate correlations between ultrasonographic pupillary assessment (UPA) and automated UPA in neurocritical patients.Methods: This was a prospective, observational study of 20 adult patients admitted to the intensive care unit with neurological pathology. Between UPA and automated UPA, 40 pupillary measurements were made. The time required to conduct UPA and automated UPA on a single patient was consistently < 3 minutes. Automated UPA required a markedly shorter operational time than UPA.Results: There were strong positive associations between UPA and automated UPA measurements, with the following correlations: right eye at rest, r = 0.9973; left eye at rest, r = 0.9989; right eye post-pupillary light response, r = 0.9975; left eye post-pupillary light response, r = 0.9955. Bland-Altman analyses confirmed the strong agreement between the two methods under both conditions, with most measurements falling within the limits of agreement. Both the right and left pupillary diameters at rest demonstrated consistency, and the post-pupillary light response measurements for both eyes indicated good agreement, with a few outliers.Conclusions: Automated UPA was strongly correlated with UPA in neurocritical patients. Automated UPA is a rapid, feasible, and noninvasive method that enables the precise evaluation of pupillary size and light response.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241299927"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11618917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142780140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

MINOCA as the result of coronary artery aneurysm thrombosis.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241301859

Oksana Rokyta

{"title":"MINOCA as the result of coronary artery aneurysm thrombosis.","authors":"Oksana Rokyta","doi":"10.1177/03000605241301859","DOIUrl":"10.1177/03000605241301859","url":null,"abstract":"Myocardial infarction (MI) can be caused by many factors. In addition to the typical obstruction or stenosis of the coronary arteries, there is heterogenic MI with non-obstructive coronary arteries (MINOCA). A rare cause of MINOCA is the thrombosis of a coronary artery aneurysm (CAA). This current case report describes a male patient with CAA thrombosis as the cause of MINOCA following surgery for a mucoepidermoid carcinoma. The patient underwent angiography that identified three CAAs that were located as follows: (i) in the proximal part of the left anterior descending artery (5.55 mm); (ii) in the distal part of the circumflex artery (8.05 mm); and (iii) in the distal part of the right coronary artery (6.61 mm). Thrombotic masses were identified within all three structures. The patient received balloon angioplasties without stent implanting and recovered well. The patient was also notable for the presence of two brain artery aneurysms that were the cause of the previous strokes that he had experienced. This case report also reviews the literature in order to: (i) summarize the aetiological factors and clinical manifestations of CAA; (ii) discuss the diagnostic methods for CAA; (iii) describe the medical and surgical management of CAA; and (iv) assess the prognosis of this rare clinical event.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241301859"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142807024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term survival of a kidney transplant patient with advanced renal cancer after combination therapy: a case report and literature review.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241304640

Chao Peng, Weihao Wang, Jiajun Chen, Shouhua Pan, Gang Xu, Mengyao Li, Lulu Zhang, Yulei Li, Keyuan Zhao, Jing Jin

{"title":"Long-term survival of a kidney transplant patient with advanced renal cancer after combination therapy: a case report and literature review.","authors":"Chao Peng, Weihao Wang, Jiajun Chen, Shouhua Pan, Gang Xu, Mengyao Li, Lulu Zhang, Yulei Li, Keyuan Zhao, Jing Jin","doi":"10.1177/03000605241304640","DOIUrl":"10.1177/03000605241304640","url":null,"abstract":"De novo renal transplant carcinoma, especially in the context of bilateral renal carcinoma, is rare and often presents as small, low-grade papillary renal cell carcinoma (RCC). There is currently no consensus or effective treatment for advanced metastatic RCC after kidney transplantation. A 40-year-old man developed de novo renal transplant carcinoma with venous thrombus and lung metastases 13 years after transplantation. The patient underwent cytoreductive nephrectomy followed by sequential treatment with tyrosine kinase inhibitors (TKI) and anti-PD-1 monoclonal antibodies. After 2 years, the patient showed excellent graft function with no evidence of cancer progression. Despite subsequent graft failure, the disease remained controlled for more than 2 years and the patient survived for more than 3 years, which was significantly longer than the typical survival of 10 to 20 months in patients with advanced kidney cancer. The results suggest that combining cytoreductive nephrectomy with TKI and anti-PD-1 therapy may significantly prolong survival in patients with renal allograft carcinoma.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241304640"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694285/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Corrigendum to "Positioning tezepelumab for patients with severe asthma: from evidence to unmet needs".

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241306931

引用次数: 0

Cerebral infarction presenting with bilateral sudden deafness as the primary symptom: a case report.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241305483

Jie Zhang, Lin Zhou, Tao Liu, Yuhan Cheng, Yanling Dou

引用次数: 0

Musculoskeletal ultrasonography versus conventional radiography: Correlation with DAS28 and MDHAQ scores in early rheumatoid arthritis.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241306397

Reem Hamdy A Mohammed, Hatem Alazizi, Asmaa Negm Eldin Taha, Seham Metawee

{"title":"Musculoskeletal ultrasonography versus conventional radiography: Correlation with DAS28 and MDHAQ scores in early rheumatoid arthritis.","authors":"Reem Hamdy A Mohammed, Hatem Alazizi, Asmaa Negm Eldin Taha, Seham Metawee","doi":"10.1177/03000605241306397","DOIUrl":"10.1177/03000605241306397","url":null,"abstract":"Objectives: To compare the value of musculoskeletal ultrasound (MSUS) with conventional radiography in the detection of patients with early rheumatoid arthritis (RA) and to correlate the sonographic findings with disease activity, and functional disability scores.Methods: Patients >18 years of age with RA ≤2 years who satisfied the 2010 EULAR/ACR classification criteria for rheumatoid arthritis and disease activity score 28 (DAS28) >2.6, were enrolled. Plain radiographs and MSUS examinations were performed on 18 joints bilaterally. DAS28 and multi-dimensional health assessment questionnaire (MDHAQ/RAPID) scores were assessed.Results: Forty patients (35 women, 5 men), mean age 41 ± 12 years, and mean disease duration 11 ± 5 months, were included. In total, 720 joints were examined. The number of hand joints affected by erosions via MSUS was 3.28-fold the number detected by X-ray. Sonographic evidence of synovitis and active erosion significantly correlated with MDHAQ, DAS28 and inflammatory biomarkers.Conclusion: Joint sonography was superior to conventional radiography in early detection of structural joint damage and active disease in patients with early RA which correlated with disease activity and functional ability scores.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241306397"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686706/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Primary hepatic epithelioid hemangioendothelioma: a case report.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241306649

Jing-Rui Wang, Qi-Jun Yang, Bei Lu, Yang Cai, Jun-Jie Yin

{"title":"Primary hepatic epithelioid hemangioendothelioma: a case report.","authors":"Jing-Rui Wang, Qi-Jun Yang, Bei Lu, Yang Cai, Jun-Jie Yin","doi":"10.1177/03000605241306649","DOIUrl":"10.1177/03000605241306649","url":null,"abstract":"Epithelioid hemangioendothelioma is a low-grade malignant tumor of vascular origin. The rarity of hepatic epithelioid hemangioendothelioma (HEHE) makes the diagnosis and treatment of this entity challenging. We report a case of a 69-year-old female patient who suffered from HEHE and complained of abdominal distension pain with dizziness and appetite loss for more than half a month. Enhanced computed tomography of the upper abdomen indicated multiple space-occupying lesions in the liver. The pathological results of color ultrasound puncture suggested HEHE. We performed transcatheter arterial chemoembolization and relevant examinations according to the patient's condition and their choice. We followed the patient for 5 years and found that she developed recurrent intrahepatic metastasis of the tumor. Computed tomography was performed again after 3 months of treatment with anlotinib and the tumor did not show any progression. HEHE is a relatively rare hepatic malignant tumor derived from vascular endothelial cells, with a low incidence, atypical clinical manifestations, and a difficult diagnosis that can only be confirmed with pathological results. Currently, appropriate treatment methods should be selected according to the specific conditions of the patient.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241306649"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686786/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142895189","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Heavily treatment-experienced patients with HIV: are new mechanisms of action enough?

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241301883

Marisa B Brizzi, Tracy L Cable, Dimple C Patel, Kelli Williams, Zoe Adjei, Carl J Fichtenbaum

引用次数: 0

Causal association between glaucoma and risk of retinal vascular occlusion: a Mendelian randomization study.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241286985

Zixun Wang, Kaihua Xu, Xiaoling Zhang, Ruihua Wei, Zhiqing Li

{"title":"Causal association between glaucoma and risk of retinal vascular occlusion: a Mendelian randomization study.","authors":"Zixun Wang, Kaihua Xu, Xiaoling Zhang, Ruihua Wei, Zhiqing Li","doi":"10.1177/03000605241286985","DOIUrl":"10.1177/03000605241286985","url":null,"abstract":"Objective: Retinal vein occlusion (RVO) leads to visual impairment, and risk factors may include glaucoma. Although some studies suggest a relationship between glaucoma and RVO, it is unknown whether this association is causal. We performed Mendelian randomization (MR) analyses to evaluate the causal contribution to RVO of five genetically predicted glaucoma conditions.Methods: We conducted two-sample univariable MR analysis using inverse variance weighting, weighted median, and MR-Egger methods. We obtained publicly available datasets of genome-wide association studies (GWAS) meta-analyses for glaucoma as the exposure and a GWAS for RVO in the Finn Gen biobank study as the outcome.Results: Genetically predicted glaucoma was causally associated with RVO risk (beta = 0.267, standard error [SE] = 0.052, odds ratio [OR] = 1.306, 95% confidence interval [CI]: 1.181-1.445). This association was supported by sensitivity analyses using weighted median (beta = 0.211, SE = 0.075, OR = 1.235, 95% CI: 1.067-1.429), weighted mode (beta = 0.491, SE = 0.132, OR = 1.633, 95% CI: 1.261-2.116), and MR-Egger (beta = 0.3900, SE = 0.138, OR = 1.476, 95% CI: 1.128-1.933) methods. MR analyses using the validation dataset obtained consistent results.Conclusion: Our results indicated that glaucoma is likely causally associated with an increased risk of RVO. The current findings may help in determining the underlying mechanisms via which glaucoma affects the risk of RVO.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241286985"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626705/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparative analysis of low-power versus high-power holmium laser enucleation of the prostate for symptomatic small-volume benign prostatic hyperplasia: a prospective randomized controlled trial.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241304542

Zhixiang Gao, Yue Ding, Haiyong Liu, Renji Du, Zhiwei Sun, Li Xu, Lijuan Gu, Ping Wang, Rong Wang

{"title":"Comparative analysis of low-power versus high-power holmium laser enucleation of the prostate for symptomatic small-volume benign prostatic hyperplasia: a prospective randomized controlled trial.","authors":"Zhixiang Gao, Yue Ding, Haiyong Liu, Renji Du, Zhiwei Sun, Li Xu, Lijuan Gu, Ping Wang, Rong Wang","doi":"10.1177/03000605241304542","DOIUrl":"10.1177/03000605241304542","url":null,"abstract":"Objective: To compare the safety and efficacy of low-power (LP) and high-power (HP) holmium laser enucleation of the prostate (HoLEP) in patients with symptomatic small-volume benign prostatic hyperplasia (BPH).Methods: In this prospective, multicenter, single-blind, randomized controlled trial, men with symptomatic BPH (prostate volume <40 mL, peak urinary flow rate [Qmax] <10 mL/s, International Prostate Symptom Score [IPSS] ≥18) underwent either LP (24 W) or HP HoLEP (80 W). The primary outcome was IPSS at 6 months postoperatively. Secondary outcomes included the surgical duration, total laser energy, enucleated prostate weight, patient-reported outcomes, and Clavien-Dindo classification of complications at 1, 3, and 6 months after surgery.Results: Eighty-one participants completed the study. LP HoLEP used significantly less energy (22.4 ± 10.4 kJ vs. 58.6 ± 17.8 kJ). Postoperative pain was lower in the LP group at 24 and 48 hours. Both groups displayed significant improvements in outcomes versus baseline including IPSS and Qmax. The incidence of intraoperative complications was similar, though minor capsular perforation occurred exclusively in the HP group (9.8%).Conclusion: LP HoLEP produced comparable clinical outcomes as HP HoLEP for small-volume BPH while using less energy, supporting its use for smaller glands.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241304542"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11648024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0