Journal of International Medical Research最新文献

{"title":"Impact of diabetes-specific nutrition formulas on time in range in overweight or obese Colombian patients with diabetes: A case series study.","authors":"Ana-M Gomez, Maria-P Chicue, Diana-C Henao, Oscar-M Muñoz-Velandia","doi":"10.1177/03000605251382375","DOIUrl":"https://doi.org/10.1177/03000605251382375","url":null,"abstract":"<p><p>The use of diabetes-specific nutrition formulas reduces postprandial glucose and insulin levels and promotes satiety, thereby improving glycemic control and contributing to weight loss. The effect of diabetes-specific nutrition formulas on the percentage of time in range (70-180 mg/dL) has not yet been investigated. This longitudinal pilot study was based on a case series of overweight or obese patients diagnosed with diabetes using continuous glucose monitoring and managed at the Hospital Universitario San Ignacio in Bogotá (Colombia). We compared continuous glucose monitoring data and anthropometric variables before and after 4 weeks of using a diabetes-specific nutrition formula as replacement for breakfast and afternoon snack. Eleven patients were included in this study; of these, 63.7% were men. The mean patient age was 55 ± 14.5 years, and 81.1% had type 2 diabetes. The mean percentage of time in range increased from 64% ± 24% to 75% ± 16% (mean difference: 10.63; 95% confidence interval: 2.13, 19.14; p = 0.01). The mean percentage of time above range (>180 mg/dL) decreased from 34% ± 25% to 23% ±14% (mean difference: -11.27; 95% confidence interval: -2.48, -20.05; p = 0.02), with no difference in hypoglycemia incidence or anthropometric variables. Our study suggests that the use of a diabetes-specific nutrition formula as replacement for breakfast and afternoon snack improves glycemic control, as measured via continuous glucose monitoring, in overweight or obese patients with type 2 diabetes. This adds to the emerging evidence on the effect of this intervention on continuous glucose monitoring metrics. Further evidence is needed from larger clinical trials to support the inclusion of this intervention in routine clinical practice.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 10","pages":"3000605251382375"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association between the C-reactive protein-albumin-lymphocyte index and severity of acute coronary syndrome: A retrospective study.","authors":"Tingting Wu, Xin Zhao, Chenchen Tu, Xiantao Song, Qiumei Cao","doi":"10.1177/03000605251381579","DOIUrl":"10.1177/03000605251381579","url":null,"abstract":"<p><p>BackgroundThe C-reactive protein-albumin-lymphocyte index integrates inflammatory and nutritional markers. However, its role in acute coronary syndrome remains unclear.MethodsWe retrospectively analyzed 765 patients with acute coronary syndrome admitted to the Beijing Anzhen Hospital between January 2021 and December 2023. The C-reactive protein-albumin-lymphocyte index, neutrophil-to-lymphocyte ratio, C-reactive protein, and systemic immune-inflammation index were calculated from admission laboratories. Severe acute coronary syndrome was defined as ST-elevation myocardial infarction; mild acute coronary syndrome included non-ST-elevation myocardial infarction and unstable angina. Multivariable logistic regression was used to identify the predictors of severe acute coronary syndrome. Discriminative performance was assessed using receiver operating characteristic analysis with DeLong's test.ResultsLower C-reactive protein-albumin-lymphocyte index values were significantly associated with severe acute coronary syndrome (adjusted odds ratio: 0.91; 95% confidence interval: 0.86-0.95; p < 0.001) after adjustment for conventional risk factors. In receiver operating characteristic analysis, the C-reactive protein-albumin-lymphocyte index (area under the curve: 0.696; 95% confidence interval: 0.658-0.735) outperformed C-reactive protein (area under the curve: 0.599), neutrophil-to-lymphocyte ratio (area under the curve: 0.624), and systemic immune-inflammation index (area under the curve: 0.560) in discriminating severe from mild acute coronary syndrome (all p ≤ 0.001 for pairwise comparisons).ConclusionsThe C-reactive protein-albumin-lymphocyte index may help identify patients with more severe acute coronary syndrome and offers superior discrimination compared with established inflammatory and nutritional markers. Prospective studies are needed for validation.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 10","pages":"3000605251381579"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12489234/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiopulmonary bypass-mediated lung ischemia-reperfusion injury: A protective role of sitaxentan.","authors":"Zhengjia Wang, Renshu Zhan, Liqun Mo, Yingying Zhang, Yirong Chen, Li Liu, Yiping Bai","doi":"10.1177/03000605251383318","DOIUrl":"https://doi.org/10.1177/03000605251383318","url":null,"abstract":"<p><p>BackgroundCardiopulmonary bypass is widely used in cardiac surgery but often leads to lung ischemia-reperfusion injury, a major cause of morbidity and mortality. Despite advances in critical care, effective prevention remains challenging. Sitaxentan, a selective endothelin receptor antagonist, has shown protective effects in ischemia-reperfusion models, suggesting its potential in mitigating lung ischemia-reperfusion injury. This study investigated the efficacy of sitaxentan in reducing lung ischemia-reperfusion injury during cardiopulmonary bypass.MethodsTwenty-four female beagles were divided into sham, cardiopulmonary bypass, and endothelin receptor antagonist (sitaxentan-treated) groups. Hemodynamics, arterial blood gas, lung damage scores, wet/dry ratio, and levels of various biomarkers were evaluated.ResultsLung damage scores in the endothelin receptor antagonist group were lower than those in the cardiopulmonary bypass group but higher than those in the sham group (<i>P</i> < 0.05). The wet/dry ratio was lowest in the sham group and higher in the cardiopulmonary bypass group than that in the endothelin receptor antagonist group (<i>P</i> < 0.05). Caspase-3 and hypoxia inducible factor-1α levels were intermediate in the endothelin receptor antagonist group compared with those in the cardiopulmonary bypass and sham groups (<i>P</i> < 0.05). In contrast, phosphorylated-endothelial nitric oxide synthase, phosphorylated protein kinase B, tumor necrosis factor-α, and interleukin-6 levels were higher in the endothelin receptor antagonist group than in the cardiopulmonary bypass and sham groups (<i>P</i> < 0.05). Malondialdehyde level was higher and superoxide dismutase level was lower in the cardiopulmonary bypass and endothelin receptor antagonist groups than in the sham group (<i>P</i> < 0.05).ConclusionsSitaxentan may offer a novel therapeutic approach to attenuate lung ischemia-reperfusion injury in clinical settings by regulating the hypoxia inducible factor-1α/phosphorylated protein kinase B/phosphorylated-endothelial nitric oxide synthase pathway.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 10","pages":"3000605251383318"},"PeriodicalIF":1.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145258235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mendelian randomization and mediation analysis reveal the role of immune cells in the pathways between inflammatory factors and glioblastoma.","authors":"Ruilong Xu, Yubo Wang, Xiaoshan Ma, Liang Zhang, Yunqian Li","doi":"10.1177/03000605251372521","DOIUrl":"10.1177/03000605251372521","url":null,"abstract":"<p><p>ObjectiveInflammatory factors and immune cells play crucial roles in glioblastoma multiforme pathophysiology. However, the relationships between these factors and the underlying mechanisms are not fully understood. This study employed Mendelian randomization to investigate the effects of inflammatory factors and immune cells on glioblastoma multiforme risk, specifically focusing on the mediating role of immune cells.MethodsGenetic data on 91 inflammatory factors (e.g. interleukins, CXCL, and fibroblast growth factor; N = 14,824), 731 immune cell phenotypic traits (e.g. CD39⁺ secreting Treg absolute count, IgD^-CD38^- absolute count, and T cell absolute count; N = 3,757), and glioblastoma multiforme risk (6,183 cases and 18,169 controls) were obtained from a genome-wide association study database. All data were derived from individuals of European ancestry. Inverse variance weighting was employed as the primary Mendelian randomization method to estimate causal effects.ResultsMendelian randomization analysis revealed significant associations between two inflammatory factors and glioblastoma multiforme risk. Furthermore, 22 immune cell phenotypic traits were associated with glioblastoma multiforme risk. Notably, Mendelian randomization mediation analysis identified two significant mediation pathways: (a) double-negative (CD4^-CD8^-) T cells mediate the causal effect of transforming growth factor β1 on glioblastoma multiforme risk and (b) human leukocyte antigen-DR⁺ T cells mediate the causal effect of CXCL10 on glioblastoma multiforme risk.ConclusionThis study provides genetic evidence supporting the complex interplay among inflammatory factors, immune cells, and glioblastoma multiforme risk, highlighting key mediation mechanisms. These findings offer novel insights into the therapeutic potential of targeting inflammatory factors within the tumor microenvironment to regulate immune cell responses.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251372521"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145069773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shear wave elastography in the differentiation of intra-abdominal hematoma and abscess.","authors":"Sercan Özkaçmaz, Mesut Özgökçe, Fatma Durmaz, Muhammed Bilal Akıncı, Muhammed Alpaslan, İlyas Dündar, Cemil Göya, Ayşe Özkaçmaz, Iskan Callı, Serhat Binici","doi":"10.1177/03000605251378696","DOIUrl":"10.1177/03000605251378696","url":null,"abstract":"<p><p>ObjectiveThe objective of this study was to examine the applicability of shear wave elastography as a quantitative approach for measuring tissue stiffness in the differentiation of intra-abdominal abscesses from hematomas, which share similar radiological findings.MethodsThis prospective single-center study included patients with intra-abdominal abscesses or hematomas who underwent shear wave elastography prior to ultrasound-guided drainage in an interventional radiology clinic between 2021 and 2022. An independent samples <i>t</i>-test was used to compare the mean shear wave velocity between the abscess and hematoma groups.ResultsA total of 50 patients (33 with abscesses and 17 with hematomas) were included in this study. The elastography values of the patients were expressed as mean ± standard deviation (minimum-maximum). The mean shear wave velocity of hematomas (1.11 ± 0.41 (0.54-1.98) m/s) was significantly higher than that of abscesses (0.68 ± 0.16 (0.36-1.07) m/s) (p < 0.001). In the receiver operating characteristic analysis, the area under the curve was 84.8%. When the optimal cutoff value was defined as 0.72, the sensitivity and specificity were 82.4% and 67%, respectively.ConclusionShear wave velocity can aid in differentiating intra-abdominal abscesses from hematomas using a simple and widely available method.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251378696"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12475709/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145175821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk analysis of cardiac disease mortality within 3 months in patients with lung cancer after surgery: A real-world cohort study.","authors":"Yimin Wu, Yun Cheng, Shuang Fu, Junbo Yuan, Jue Shen, Shunv Cai","doi":"10.1177/03000605251378947","DOIUrl":"10.1177/03000605251378947","url":null,"abstract":"<p><p>ObjectiveTo determine the 3-month heart disease-related mortality rate among patients with lung cancer who have undergone lobectomy and identify the common risk factors for mortality to provide a basis for clinical risk assessment and intervention strategies.MethodsWe conducted a retrospective cohort study using the Surveillance, Epidemiology, and End Results Program database (2010-2015), including 35,094 patients with stage I-III lung cancer who underwent surgery. Logistic regression analyzed mortality at 3, 7, and 11 months, focusing on non-cancer causes, particularly heart diseases.ResultsAmong the 35,094 patients, 3.24% (1138) died within 3 months, with heart disease accounting for 8.96% (102) of the deaths, a significantly higher percentage than that at 4-7 months (p = 0.017). Logistic regression analysis showed that several factors, including sex, age, postoperative radiotherapy, and postoperative systematic treatment were independent factors contributing to mortality owing to heart diseases within 3 months of surgery.ConclusionsIn this study, we analyzed the causes of early death in patients who had undergone lung cancer surgery and determined the independent risk factors associated with 3-month mortality due to heart disease in these patients.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251378947"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464387/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Omics-based integrative analysis of sepsis-induced myocardial dysfunction.","authors":"Jie-Wen Zhao, Zeng-Xiang Dong, Wei Wang, Si-Qi Sheng, Kai-Jiang Yu","doi":"10.1177/03000605251377660","DOIUrl":"10.1177/03000605251377660","url":null,"abstract":"<p><p>ObjectiveSepsis-induced myocardial dysfunction is a common complication of sepsis, characterized by high mortality and an unclear underlying mechanism. This study conducted an integrative multiomics analysis of mice with sepsis-induced myocardial dysfunction to provide new insights into potential mechanisms.MethodWe constructed an animal model of sepsis-induced myocardial dysfunction and analyzed the metabolomics, transcriptomics, and protein profiles of the heart tissues in the control and experimental groups.ResultsUntargeted metabolomics identified 74 significantly altered metabolites in the positive ion mode, of which 48 were upregulated and 26 downregulated; moreover, 70 significantly altered metabolites were detected in the negative ion mode, with 50 being upregulated and 20 downregulated. Transcriptomics revealed 4831 differentially expressed genes, with 3027 being downregulated and 1804 upregulated. Proteomics identified 107 significant proteins, 94 of which were significantly upregulated and 13 significantly downregulated. Integrated omics analysis revealed three significantly altered metabolites common to both groups: L-glutamate, L-aspartate, and nicotinamide. These metabolites were predominantly involved in nicotinate and nicotinamide metabolism, histidine metabolism, and nitrogen metabolism, potentially related to the pathogenesis of sepsis-induced myocardial dysfunction.ConclusionThe pathogenesis of sepsis-induced myocardial dysfunction in mice may be associated with alterations in nicotinate and nicotinamide metabolism, histidine metabolism, and nitrogen metabolism.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251377660"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12480772/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of <i>FAM13A</i> single-nucleotide polymorphism with spirometry indices and pulmonary ventilation characteristics in patients with chronic obstructive pulmonary disease.","authors":"Binh Huy Nguyen, Nhung Thi Cam Tran, Chuong Quoc Ho, Tam Thai Thanh Tran, Hong Ngoc Phan, De Van Tran, Nga Thi Ngoc Pham, Kien Trung Nguyen, Khanh Hoang Pham","doi":"10.1177/03000605251372069","DOIUrl":"10.1177/03000605251372069","url":null,"abstract":"<p><p>ObjectivesGenome-wide association studies have identified <i>FAM13A</i> as a gene linked to chronic obstructive pulmonary disease. Several single-nucleotide polymorphisms-notably, rs7671167, rs2869967, rs2869966, and rs17014601-are associated with chronic obstructive pulmonary disease susceptibility and spirometric indices. This study aimed to investigate the association between <i>FAM13A</i> single-nucleotide polymorphisms and spirometric indices in chronic obstructive pulmonary disease and non-chronic obstructive pulmonary disease patients and assess the correlation of these single-nucleotide polymorphisms with pulmonary ventilation function.MethodsThis study included 160 participants (80 chronic obstructive pulmonary disease patients and 80 controls) who underwent clinical evaluation and spirometry at Can Tho University of Medicine and Pharmacy Hospital from March 2021 to February 2023.ResultsThe mean patient age was 66.3 ± 7.9 years. Significant differences in allele frequencies of the studied single-nucleotide polymorphisms were observed between the two groups. TT genotypes at rs7671167 and rs17014601 and CT genotypes at rs7671167, rs2869967, and rs2869966 were associated with significant differences in forced vital capacity, forced expiratory volume in 1 second, and Tiffeneau index.ConclusionThe CT genotype at rs7671167, rs2869967, and rs2869966 is significantly associated with altered spirometric parameters, suggesting a role in chronic obstructive pulmonary disease-related lung function impairment.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251372069"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12409044/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144957227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A fatal case report of <i>Plasmodium falciparum</i> malaria complicated by acute subdural hematoma.","authors":"Na Xie, Hemei Ye, Xin Jiang","doi":"10.1177/03000605251372432","DOIUrl":"10.1177/03000605251372432","url":null,"abstract":"<p><p>This case details a male patient in his late 50s weighing 90 kg who traveled to Burkina Faso, Africa, for approximately 1 month. He developed fever, headache, and generalized myalgia 3 days after returning to Chongqing, China. The interval from the emergence of the patient's symptoms to the diagnosis of severe falciparum malaria and the commencement of artesunate treatment was 9 days. Despite effective anti-<i>Plasmodium falciparum</i> treatment, the patient ultimately succumbed to multiple organ failure caused by <i>P. falciparum</i> infection complicated by an acute subdural hematoma.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251372432"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12408991/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144992486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of stellate ganglion block on postoperative nausea and vomiting after general anesthesia: A meta-analysis.","authors":"Shuai Miao, Shixiao Tang, Jingjing Xu, Guodong Song, Shuhan Gu, Wankun Chen, Xin Zhang, Yiling Qian","doi":"10.1177/03000605251378691","DOIUrl":"10.1177/03000605251378691","url":null,"abstract":"<p><p>ObjectiveTo identify the effect of stellate ganglion block on the incidence of postoperative nausea and vomiting.MethodsWe systematically searched electronic databases for published randomized controlled trials comparing stellate ganglion block with placebo for reducing postoperative nausea and vomiting. The primary outcome was the incidence of postoperative nausea and vomiting after general anesthesia. Meta-regression analysis was performed to investigate potential sources of heterogeneity. Trial sequential analysis was also carried out to calculate the required information size.ResultsIn total, 16 randomized controlled trials including 1385 patients were included in the study. Stellate ganglion block significantly reduced the incidence of postoperative nausea and vomiting (relative risk, 0.59; 95% confidence interval, 0.49-0.70; <i>P </i><<i> </i>0.0001). Our meta-regression analysis confirmed that the significant correlation between stellate ganglion block and reduced postoperative nausea and vomiting risk remained robust and was not significantly influenced by study-level characteristics, including prophylactic antiemetic use, surgical technique, postoperative analgesia, female proportion, age, opioid administration, and inhalation anesthesia. In addition, trial sequential analysis indicated that the Z curve for stellate ganglion block not only crossed the conventional boundary but also the trial sequential analysis boundary for benefit.ConclusionThis meta-analysis suggested an association of stellate ganglion block with a decreased incidence of postoperative nausea and vomiting after general anesthesia. Trial sequential analysis showed that further studies are unlikely to alter the conclusions regarding the incidence of postoperative nausea and vomiting.<b>PROSPERO registration number:</b> CRD42024504829.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 9","pages":"3000605251378691"},"PeriodicalIF":1.5,"publicationDate":"2025-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12464394/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}