Journal of International Medical Research最新文献_第2页

Heat stroke with sepsis: A case report and review of the literature.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251315353

Suyu Wei, Liang Sun

引用次数: 0

Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251314804

Saja Karaja, Ahmad Almohamed, Ayham Qatza, Ahmed Aldolly, Sanaa Mansour, Alae Aldin Almasri

{"title":"Cutaneous metastases of invasive lobular breast cancer as the first clinical manifestation: a case report.","authors":"Saja Karaja, Ahmad Almohamed, Ayham Qatza, Ahmed Aldolly, Sanaa Mansour, Alae Aldin Almasri","doi":"10.1177/03000605251314804","DOIUrl":"10.1177/03000605251314804","url":null,"abstract":"Cutaneous metastasis (CM) is a rare phenomenon, occurring in only 0.6% to 10.4% of oncology patients. Breast carcinoma represents nearly one-third of all CM cases, although it manifests in a minority of patients with breast cancer (BC). Notably, CMs are detected at the time of primary tumor diagnosis in 6.3% of patients with BC and serve as the initial clinical presentation in only 3.5% of patients. We present a case involving a 53-year-old woman with a 5-month history of asymptomatic infiltrating nodules in the axillae and trunk. Skin biopsy and immunohistochemical analysis confirmed metastatic breast carcinoma with positive estrogen receptor staining. This case underscores the importance of early detection and precise diagnostic techniques in managing metastatic adenocarcinoma with cutaneous manifestations. Despite the promising outcome of the initial treatment, the disease progression in this case highlights the aggressive nature of CMs and the ongoing need for research and advanced therapeutic strategies.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251314804"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nonobstructive gastroduodenal intussusception characterized by severe anemia: a case report.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605241312831

Benlei Zhu, Congming Wang, Jingwei Fu

引用次数: 0

Minimally invasive lateral, posterior, and posterolateral sacroiliac joint fusion for low back pain: a systematic review and meta-analysis.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251315300

Kai Xu, Ya-Ling Li, Song-Hua Xiao, Yong-Wei Pan

{"title":"Minimally invasive lateral, posterior, and posterolateral sacroiliac joint fusion for low back pain: a systematic review and meta-analysis.","authors":"Kai Xu, Ya-Ling Li, Song-Hua Xiao, Yong-Wei Pan","doi":"10.1177/03000605251315300","DOIUrl":"10.1177/03000605251315300","url":null,"abstract":"Objective: This study aimed to evaluate the therapeutic effects of minimally invasive lateral, posterior, and posterolateral sacroiliac joint fusion for low back pain through a meta-analysis.Methods: The PubMed, Web of Science, Embase, Cochrane Library, and ClinicalTrials.gov databases were comprehensively searched for studies up to 31 August 2024. Relevant studies using lateral, posterior, and posterolateral approaches were identified. Pooled outcomes and publication bias were assessed. The study was registered with PROSPERO (registration No. CRD42023451047).Results: A total of 48 studies were included: 32 focused on the lateral approach, 10 on the posterior approach, four on the posterolateral approach, and two compared the lateral and posterolateral approaches. The pooled effect analysis showed statistically significant improvements in the visual analog scale (VAS) scores for all three approaches at 6 and 12 months postoperatively. Although no between-approach comparisons were conducted, the pooled improvements in VAS scores at 6 and 12 months postoperatively were numerically similar across all three approaches, as were the pooled fusion rates. The pooled complication rate for the lateral approach was 9.2%, numerically higher than 1% for the posterior approach. The pooled revision rate for the lateral approach was 2.4%, also numerically higher than 0.6% for the posterior approach.Conclusions: Although pain relief and fusion rates were similar across all approaches, the lateral approach might be associated with a higher risk of total complications and revision surgery.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251315300"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806475/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Diagnostic accuracy of high-resolution melting curve analysis for discrimination of oncology-associated EGFR mutations: a systematic review and meta-analysis.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605241311133

Shu Yu, Yan Cheng, Chen-Cheng Tang, Yue-Ping Liu

{"title":"Diagnostic accuracy of high-resolution melting curve analysis for discrimination of oncology-associated EGFR mutations: a systematic review and meta-analysis.","authors":"Shu Yu, Yan Cheng, Chen-Cheng Tang, Yue-Ping Liu","doi":"10.1177/03000605241311133","DOIUrl":"https://doi.org/10.1177/03000605241311133","url":null,"abstract":"Objective: To investigate the diagnostic value of high-resolution melting (HRM) analysis for oncology-associated epidermal growth factor receptor (EGFR) gene mutations.Methods: We systematically searched Embase, PubMed, and Web of Science for HRM and EGFR mutation detection studies published through September 2024. True and false positives and negatives were extracted to evaluate the diagnostic accuracy of HRM to detect EGFR mutations. The study was registered at INPLASY (INPLASY202490062).Results: Twenty-six articles were obtained from 416 references. The overall diagnostic sensitivity and specificity were high at 0.95 [95% confidence interval (CI), 0.94-0.96] and 0.99 (95% CI, 0.99-0.99), respectively. Other indicators, including the positive likelihood ratio, negative likelihood ratio, and diagnostic odds ratio, were 144.91 (95% CI: 69.07-304.04), 0.08 (95% CI: 0.04-0.13), and 2405.21 (95% CI: 1231.87-4696.13), respectively. The Q value of the summary receiver operating characteristic curve was 0.979, and the area under the curve was 0.997.Conclusion: As a pre-screening method, the high specificity, sensitivity, low cost, rapid turnaround, and simplicity of HRM make it a good alternative for clinical practice, but positive results must still be obtained for diagnostic confirmation. This study provides a transparent overview of relevant studies in design and conduct.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605241311133"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143390969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gastric inflammatory myofibroblastic tumor invading the esophagus and spleen: a rare case report and literature review.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251314800

LuoLan Zou, ZiLing Yan, HuaZhen Deng, HongPeng Liu, Ying Qin

引用次数: 0

Efficacy and safety of laquinimod versus placebo in relapsing-remitting multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605241311437

Malik Waleed Zeb Khan, Aizaz Ali, Amna Hussain, Safeena Khan, Ammara Tahir, Muhammad Haris Khan, Touba Azeem, Abdul Moeez, Arysha Monis, Aban Masaud Mian, Fazia Khattak, Moosa Ali, Jibran Ikram

{"title":"Efficacy and safety of laquinimod versus placebo in relapsing-remitting multiple sclerosis: a systematic review and meta-analysis of randomized controlled trials.","authors":"Malik Waleed Zeb Khan, Aizaz Ali, Amna Hussain, Safeena Khan, Ammara Tahir, Muhammad Haris Khan, Touba Azeem, Abdul Moeez, Arysha Monis, Aban Masaud Mian, Fazia Khattak, Moosa Ali, Jibran Ikram","doi":"10.1177/03000605241311437","DOIUrl":"10.1177/03000605241311437","url":null,"abstract":"Objective: To investigate the safety and efficacy of laquinimod in treating relapsing-remitting multiple sclerosis (RRMS).Methods: An extensive electronic search was conducted across PubMed, Embase, Cochrane Database of Systematic Reviews, and ClinicalTrials.gov to identify suitable studies. Risk of bias was assessed using Cochrane's Risk of Bias tool. Statistical analysis was performed using RevMan 5.4.1.Results: The meta-analysis of four randomized controlled trials including 3665 patients found that laquinimod significantly reduced the annualized relapse rate compared with placebo (mean difference = -0.08, 95% confidence interval [CI] = -0.12, -0.04, I2 = 0%). For disability progression confirmed at 3 months, laquinimod provided a significant advantage over placebo (hazard ratio [HR] = 0.75, 95% CI = 0.59, 0.96, I2 = 25%), whereas no benefit was achieved at 6 months (HR = 0.69, 95% CI = 0.45, 1.06, I2 = 66%). Laquinimod was also significantly better than placebo in maintaining a relapse-free status (risk ratio [RR] = 1.14 95% CI = 1.06, 1.22, I2 = 10%). Laquinimod had a comparable safety profile as placebo (RR = 1.06, 95% CI = 0.81, 1.39, I2 = 33%).Conclusions: These findings support the efficacy of laquinimod in managing RRMS but necessitate careful monitoring during treatment.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605241311437"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11806468/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coexistence of giant cell arteritis and subacute thyroiditis: A case report and literature review.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251315333

Cheng Xu, Yongmei Han

引用次数: 0

Intravenous amino acids for kidney protection in patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized controlled trials.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251315919

Malik Waleed Zeb Khan, Aizaz Ali, Amna Hussain, Aban Masaud Mian, Abdul Moeez, Waqas Inayat, Bushra Noor, Izhar Ali Shah, Muhammad Osama, Bushra Khan, Muhammad Sajid, Touba Azeem, Mohammad Ebad Ur Rehman, Ashraf Ali, Ubaid Khan Afridi

{"title":"Intravenous amino acids for kidney protection in patients undergoing cardiac surgery: A systematic review and meta-analysis of randomized controlled trials.","authors":"Malik Waleed Zeb Khan, Aizaz Ali, Amna Hussain, Aban Masaud Mian, Abdul Moeez, Waqas Inayat, Bushra Noor, Izhar Ali Shah, Muhammad Osama, Bushra Khan, Muhammad Sajid, Touba Azeem, Mohammad Ebad Ur Rehman, Ashraf Ali, Ubaid Khan Afridi","doi":"10.1177/03000605251315919","DOIUrl":"10.1177/03000605251315919","url":null,"abstract":"Objective: To evaluate the efficacy of intravenous (IV) amino acids in preventing acute kidney injury (AKI) in patients undergoing cardiac surgery.Methods: PubMed, EMBASE, and Cochrane Library databases were systematically searched for all relevant randomised controlled trials (RCTs) published from inception to July 25, 2024. A random effects model was used to pool the risk ratios (RR) for dichotomous outcomes, and the combined data was visually represented using forest plots.Results: 3 studies involving 3646 patients were included in the meta-analysis. IV amino acids did not significantly lower the overall AKI incidence compared with control measures. However, they significantly reduced the risk of Stage 1 AKI and Stage 3 AKI. No differences were observed between intervention and control for Stage 2 AKI or need for kidney replacement therapy.Conclusion: IV amino acids may offer protective benefits against severe AKI stages in cardiac surgery patients. Further studies are warranted to validate our findings.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251315919"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792033/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pre-trained convolutional neural network with transfer learning by artificial illustrated images classify power Doppler ultrasound images of rheumatoid arthritis joints.

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-02-01 DOI: 10.1177/03000605251318195

Jun Fukae, Yoshiharu Amasaki, Yuichiro Fujieda, Yuki Sone, Ken Katagishi, Tatsunori Horie, Tamotsu Kamishima, Tatsuya Atsumi

{"title":"Pre-trained convolutional neural network with transfer learning by artificial illustrated images classify power Doppler ultrasound images of rheumatoid arthritis joints.","authors":"Jun Fukae, Yoshiharu Amasaki, Yuichiro Fujieda, Yuki Sone, Ken Katagishi, Tatsunori Horie, Tamotsu Kamishima, Tatsuya Atsumi","doi":"10.1177/03000605251318195","DOIUrl":"10.1177/03000605251318195","url":null,"abstract":"Objective: To study the classification performance of a pre-trained convolutional neural network (CNN) with transfer learning by artificial joint ultrasonography images in rheumatoid arthritis (RA).Methods: This retrospective study focused on abnormal synovial vascularity and created 870 artificial joint ultrasound images based on the European League Against Rheumatism/Outcome Measure in Rheumatology scoring system. One CNN, the Visual Geometry Group (VGG)-16, was trained with transfer learning using the 870 artificial images for initial training and the original plus five additional images for second training. The models were then tested for the ability to classify joints using real joint ultrasound images obtained from patients with RA. The study was registered in UMIN Clinical Trials Registry (UMIN000054321).Results: A total of 156 clinical joint ultrasound images from 74 patients with RA were included. The initial model showed moderate classification performance, but the area under curve (AUC) for grade 1 synovitis was particularly low (0.59). The second model showed improvement in classifying grade 1 synovitis (AUC 0.73).Conclusions: Artificial images may be useful for training VGG-16. The present novel approach of using artificial images as an alternative to actual images for training a CNN has the potential to be applied in medical imaging fields that face difficulties in collecting real clinical images.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 2","pages":"3000605251318195"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795604/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0