{"title":"Sudden airway obstruction during emergence from general anesthesia in a post-radiation nasopharyngeal carcinoma patient with lower cranial nerve injury: A case report.","authors":"Wei-Chao Zhu, Li Hu, Shuai Kang","doi":"10.1177/03000605251325655","DOIUrl":"10.1177/03000605251325655","url":null,"abstract":"<p><p>This article presents a case study of airway obstruction encountered during the post-anesthetic recovery period in a patient with nasopharyngeal carcinoma who had suffered cranial nerve damage subsequent to radiation therapy. It underscores the necessity for meticulous preoperative preparation during the induction of anesthesia and a comprehensive assessment coupled with careful preparation prior to extubation in the recovery phase. These measures are crucial to guarantee the safety of perioperative anesthesia in such patients. The case report is intended to contribute to the clinical knowledge base for anesthesiologists managing patients with nasopharyngeal carcinoma who have experienced post-radiation cranial nerve impairment. This case report has been meticulously crafted in compliance with the CARE (Case Reports) guideline, ensuring a standardized and rigorous approach to presenting the patient's medical history, diagnosis, treatment, and outcomes.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251325655"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11930465/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Retraction: Nephroprotective effect of losartan in IgA model rat.","authors":"","doi":"10.1177/03000605251330127","DOIUrl":"https://doi.org/10.1177/03000605251330127","url":null,"abstract":"","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251330127"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143764099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Optimal trajectory for the anterior occipital condyle screw.","authors":"Zhenqi Lou, Jieyang Zhu, Kanling Jiang, Sanqiang Xia, Sihui Chen, Jinyu Zhu, Yi Jiang","doi":"10.1177/03000605251325677","DOIUrl":"10.1177/03000605251325677","url":null,"abstract":"<p><p>ObjectiveThis study aimed to assess the practicality and optimal approach for inserting an anterior occipital condyle screw, as well as to measure the screw placement characteristics.MethodsA total of 80 normal head and cervical spine computed tomography scans (40 males/40 females) were used to construct three-dimensional models. The average age of the participants was 45.18 ± 8.86 years (ranging from 25 to 65 years). Three potential entry points for the anterior occipital condyle screw were identified. A simulated screw with a radius of 1.75 mm was created to replicate the screw trajectory and adjusted to establish the maximum and minimum cranial limits for each entry point. The feasibility of screw fixation was assessed, identifying the optimal entry point and analyzing relevant screw placement measurements.ResultsThe success rates for screw placement were 95.6%, 94.4%, and 88.1% for the middle, lateral, and medial entry points, respectively. The success rate for the medial entry point was notably lower than that for the middle and lateral points. No statistically significant differences were found in the measured parameters between the left and right sides. The medial entry point exhibited the highest abduction angulation (35.72° ± 2.01°) for screw placement, followed by the middle (25.96° ± 1.86°) and lateral (15.14° ± 1.82°) points. The middle and lateral entry points displayed a considerably wider safe range of cranial angulation and screw placement length than the medial entry point. All three entry points achieved success rates exceeding 90% when the cranial angulation ranged from 2° to 6°.ConclusionThe anterior occipital condyle screw presents a workable choice for anterior craniovertebral fixation. The middle entry point is identified as the optimal approach for placing 3.5-mm diameter screws.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251325677"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905021/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615581","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fekadu H Getaneh, Bezamariam F Kassa, Lidet G Amha, Ferehiwot B Getaneh
{"title":"Ultrasound characteristics and correlation with estimated glomerular filtration rate in patients with chronic kidney disease: A facility-based cross-sectional study.","authors":"Fekadu H Getaneh, Bezamariam F Kassa, Lidet G Amha, Ferehiwot B Getaneh","doi":"10.1177/03000605251327484","DOIUrl":"https://doi.org/10.1177/03000605251327484","url":null,"abstract":"<p><p>ObjectiveTo evaluate grayscale sonographic characteristics and their correlation with the estimated glomerular filtration rate.Methodology: This cross-sectional study included 103 patients with stage III and above chronic kidney disease. Correlation between ultrasonography measurements and estimated glomerular filtration rate was performed. Differences in the mean estimated glomerular filtration rate were evaluated using one-way analysis of variance.ResultsThe mean (± SD) estimated glomerular filtration rate was 34.47 ± 15.81 mL/min/1.73 m<sup>2</sup> (range: 9.6-45.9 mL/min/1.73 m<sup>2</sup>). The mean (± SD) average renal length was 8.97 ± 1.42 cm. The mean parenchymal and cortical thicknesses were 1.36 ± 0.45 and 0.85 ± 0.27 cm, respectively. There was a significant correlation between the estimated glomerular filtration rate and the average renal length, relative renal length, and parenchymal thickness (r = 0.26, p = 0.009; r = 0.25, p = 0.01; and r = 0.25, p = 0.01, respectively). A statistically significant negative correlation was observed between renal echogenicity and estimated glomerular filtration rate (p < 0.001).ConclusionA correlation was noted between the degree of renal function loss and sonographic findings. This indicates that ultrasound can be used in combination with other modalities for the diagnosis, assessment, and monitoring of chronic kidney disease.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251327484"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiangchun Xu, Xuzheng Guo, Jinhui Chen, Yuhua Pan, Jing Li, Jing Chen, Weihua Lai, Lu Lin
{"title":"Abemaciclib-associated kidney injuries: A retrospective analysis of the United States Food and Drug Administration adverse events reporting system.","authors":"Xiangchun Xu, Xuzheng Guo, Jinhui Chen, Yuhua Pan, Jing Li, Jing Chen, Weihua Lai, Lu Lin","doi":"10.1177/03000605251325961","DOIUrl":"https://doi.org/10.1177/03000605251325961","url":null,"abstract":"<p><p>BackgroundAbemaciclib, an oral kinase inhibitor, is used to treat hormone receptor-positive and HER2-negative breast cancer patients. However, there has been a decrease in studies reporting adverse reactions to abemaciclib-related kidney injuries. Thus, this study was aimed at assessing its safety profile using a large-scale pharmacovigilance database.MethodsAbemaciclib-related adverse drug reaction reports from the Food and Drug Administration Adverse Event Reporting System were obtained and scrutinized, and adverse drug reactions were selected using reporting odds ratio, the proportional reporting ratio methods, empirical Bayes geometric mean and UK Medicines and Healthcare products Regulatory Agency methods.ResultsWe selected 10,757 matched reports associated with abemaciclib, among which we found eight adverse reactions about kidney injuries correlated with abeamciclib, such as increased blood creatinine, renal disorder, decreased glomerular filtration rate, increased blood urea, hydronephrosis, abnormal renal function test, increased creatinine renal clearance and increased cystatin C. A demographic analysis of reported cases of abemaciclib-associated renal injury revealed that the majority were female, aged ≥46 years and had taken the drug ≥30 days.ConclusionThis study highlights the characteristics of adverse reactions with abemaciclib and those associated with renal damage, which are crucial for safety studies on the clinical use of this drug.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251325961"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143674169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Case report: False-positive B-type natriuretic peptide results with the cyclic amplified fluorescence immunoassay.","authors":"Qian Yin, Fei Wang, Chen Zhang, Yi-Bin Pan","doi":"10.1177/03000605251325942","DOIUrl":"10.1177/03000605251325942","url":null,"abstract":"<p><p>B-type natriuretic peptide, which was initially isolated from porcine brain tissue, has been used in the clinic as an important indicator for the diagnosis, risk stratification, and prognosis of heart failure. In recent years, many commercial immunoassays to assess B-type natriuretic peptide have been reported to undergo interference due to various factors. At present, the commonly used assays to assess B-type natriuretic peptide are enzyme-linked immunosorbent assay and direct chemiluminescence, which are based on a \"sandwich structure\" formed by dual antibodies; both assays have been reported to undergo interference. We report the case of a patient whose B-type natriuretic peptide results, which were detected using a cyclic amplified fluorescence immunoassay, were false-positive. The patient had a low-risk pulmonary embolism without right heart failure; however, her B-type natriuretic peptide results were surprisingly high. Further study confirmed that the abnormal B-type natriuretic peptide result was caused by the interference of the human anti-mouse antibodies. Therefore, when encountering B-type natriuretic peptide results that are not consistent with the clinical situation, the possibility of interference in the assay should be considered.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251325942"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938879/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lihong Xiao, Youhua Wang, Xiangxiang Shi, Haowen Pang, Yunfei Li
{"title":"Computed tomography-based radiomics modeling to predict patient overall survival in cervical cancer with intensity-modulated radiotherapy combined with concurrent chemotherapy.","authors":"Lihong Xiao, Youhua Wang, Xiangxiang Shi, Haowen Pang, Yunfei Li","doi":"10.1177/03000605251325996","DOIUrl":"10.1177/03000605251325996","url":null,"abstract":"<p><p>ObjectiveThe objective of this study was to develop a predictive model combining radiomic characteristics and clinical features to forecast overall survival in cervical cancer patients treated with intensity-modulated radiotherapy and concurrent chemotherapy.MethodsIn this retrospective observational study, 159 patients were divided into a training group (n = 95) and a validation group (n = 64). Radiomic characteristics were extracted from contrast-enhanced computed tomography scans. The least absolute shrinkage and selection operator regression analysis was used to filter the extracted radiomic characteristics and reduce the dimensionality of the data. A radiomic score was calculated from the selected features, and multivariate Cox regression models were established to analyze overall survival. A nomogram combining radiomic score and clinical features was developed, and its reliability was assessed using the area under the receiver operating characteristic curve.ResultsFour radiomic characteristics and two clinical features were extracted for overall survival analysis. A nomogram combining these factors was developed and validated, showing good performance with a high C-index. Patients were categorized as low-risk or high-risk for overall survival based on a cut-off value.ConclusionsOur model combining computed tomography-extracted radiomic characteristics and clinical features shows good potential for evaluating overall survival in cervical cancer patients treated with intensity-modulated radiotherapy and concurrent chemotherapy.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251325996"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143677036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Acute myeloid leukemia with <i>DEK::NUP214</i> fusion resembling acute promyelocytic leukemia, initially presenting as sweet syndrome: A case report and literature review.","authors":"Huan Liu, Guo-Xia Liu, Feng-Hai Liu, Shu-Guo Wang","doi":"10.1177/03000605251327476","DOIUrl":"10.1177/03000605251327476","url":null,"abstract":"<p><p>Some subtypes of acute myeloid leukemia share morphologic, immunophenotypic, and clinical features of acute promyelocytic leukemia but lack a promyelocytic leukemia-retinoic acid receptor alpha fusion gene. Herein, we present a case of acute myeloid leukemia with morphological and clinical features resembling those of acute promyelocytic leukemia, carrying the rare DEK::NUP214 fusion gene and presenting with sweet syndrome as the initial manifestation. In our case, the patient with acute myeloid leukemia carrying <i>DEK::NUP214</i> fusion exhibited highly active bone marrow proliferation, with increased basophil and promyelocyte counts. To the best of our knowledge, this is the first reported case of acute promyelocytic leukemia-like acute myeloid leukemia carrying <i>DEK::NUP214</i> fusion.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251327476"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11951429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Aslanger pattern: A case report.","authors":"Zhixiong Zhong","doi":"10.1177/03000605251327380","DOIUrl":"10.1177/03000605251327380","url":null,"abstract":"<p><p>Patients with Aslanger pattern are characterized by a more conspicuous incidence of multivessel coronary artery disease, a more remarkable probability of chronic complete occlusion, and a more alarming rate of hospitalization. Owing to the insufficient understanding of electrocardiographic characteristics of Aslanger pattern by a multitude of clinicians, it is commonly undetected or misdiagnosed as reversible inferior myocardial ischemia, which gives rise to prolonged reperfusion time. The electrocardiographic characteristics of Aslanger pattern cannot be stereotyped. Aslanger pattern typically indicates a higher likelihood of multivessel disease and a prevalent occurrence of acute coronary occlusion, with electrocardiographic changes being complex in such cases of multivessel disease. Aslanger pattern must be managed in accordance with ST elevation myocardial infarction. Both emergency interventional therapy and coronary artery bypass grafting are appropriate.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251327380"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954596/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143730423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Association between mandibular third molar impactions and distal carious lesions on the adjacent second molars: A cross-sectional study.","authors":"Naji Z Arandi, Ahmad Jarrar","doi":"10.1177/03000605251324489","DOIUrl":"10.1177/03000605251324489","url":null,"abstract":"<p><p>ObjectiveThis study aimed to evaluate the prevalence and patterns of impacted mandibular third molars (MTMs) and their association with distal caries in adjacent mandibular second molars (MSMs).MethodsA total of 2000 randomly selected orthopantomograms (OPGs) were analyzed. MTM impaction patterns were classified using Winter's and Pell-Gregory systems, and distal caries on MSMs were assessed. Statistical analyses included chi-square tests and multivariate logistic regression to evaluate associations between impaction characteristics and caries prevalence.ResultsOf the 1594 eligible OPGs, 37% exhibited MTM impactions. Among the 828 impacted MTMs identified, 19.56% were associated with carious lesions on the distal surface of adjacent MSMs. Statistical analysis revealed that mesioangular impactions significantly increased the likelihood of distal caries in MSMs. In contrast, Pell-Gregory Classes II-C and III-C were associated with reduced odds of caries. Age emerged as a strong predictor, whereas gender and other Winter's classification categories did not significantly influence caries occurrence.ConclusionImpacted MTMs are associated with an increased risk of caries on the distal surface of MSMs. Impaction patterns and patient age influenced the prevalence of caries. Prophylactic removal of impacted MTMs in high-risk cases may help reduce the risk of caries development in MSMs.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251324489"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907514/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}