Journal of International Medical Research最新文献

{"title":"Severe tinea faciei mimicking favus-like lesions linked to rabbit exposure: A case report.","authors":"Bo Sang, Xiaokang Xu, Xiujiao Xia","doi":"10.1177/03000605251345893","DOIUrl":"10.1177/03000605251345893","url":null,"abstract":"<p><p>Tinea faciei caused by zoophilic dermatophytes can simulate several facial inflammatory skin conditions, such as eczema, lupus erythematosus, and cellulitis, often leading to misdiagnosis or a delayed diagnosis. A young girl around primary school age developed inflammatory, favus-like lesions on the face after the purchase of a pet rabbit. The patient had been evaluated at a local clinic where she received treatment with dexamethasone acetate cream topically twice daily for suspected eczema. Mycological examination confirmed that both the patient and her rabbit were affected by tinea corporis, which was caused by <i>Trichophyton mentagrophytes</i>. This case underscores the importance of considering tinea faciei in children presenting with inflammatory facial rashes, especially when there is a history of contact with pets. Moreover, it is crucial to implement protective measures to prevent children from contracting zoonotic dermatophytosis through contact with domestic animals.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251345893"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225635","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Successful awake tracheal intubation in a morbidly obese patient with severe obstructive sleep apnea-hypopnea syndrome and a giant vocal cord polyp: A case report.","authors":"Tieshuai Liu, Ziming Zhang, Du Zheng, Qing Qiao","doi":"10.1177/03000605251345971","DOIUrl":"10.1177/03000605251345971","url":null,"abstract":"<p><p>Giant vocal cord polyps pose challenges in airway management, particularly in patients with severe obstructive sleep apnea-hypopnea syndrome. We present the case of a morbidly obese man in his 20s (body mass index: 50.8 kg/m²) with severe obstructive sleep apnea-hypopnea syndrome and a giant vocal cord polyp. He successfully underwent awake tracheal intubation using video laryngoscopy and high-flow nasal oxygen, which was administered at 30 L/min. Airway anesthesia was achieved with lidocaine, including bilateral superior laryngeal nerve blocks. A 6.5-mm endotracheal tube was placed within 30 s, maintaining the peripheral capillary oxygen saturation level at 100%. The patient remained cooperative and spontaneously breathing throughout the procedure. No complications were observed postoperatively, and the patient was discharged the following day. This case illustrates the effectiveness of awake tracheal intubation and provides valuable insights into managing complex airway cases.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251345971"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144234352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Liver functions and medication adherence in tuberculosis patients after 6 months of antituberculosis treatment in Indonesia.","authors":"Dyah Aryani Perwitasari, Triantoro Safaria, Didik Setiawan, Haafizah Dania, Salma Auliya Fatimah, Imaniar Noor Faridah","doi":"10.1177/03000605251348228","DOIUrl":"10.1177/03000605251348228","url":null,"abstract":"<p><p>ObjectiveThe objective of this study was to assess liver functions in tuberculosis patients after 6 months of treatment and determine the difference in the level of liver enzymes based on medication adherence and patient characteristics.MethodsWe used a prospective cohort design. The inclusion criteria were adult tuberculosis patients treated with the first line of antituberculosis drugs. The patients' adherence to medication was measured using the Medication Adherence Rate Scale questionnaire. We also measured the total bilirubin, aspartate aminotransferase, and alanine aminotransferase levels over 2, 4, and 6 months of treatment.ResultsThere were 233 tuberculosis patients enrolled in this study, with 58.91% male patients and the mean age of 40.31 (SD: 18.00) years. Overall, 86.3% of the patients had good medication adherence. The patients reported increased levels of aspartate aminotransferase (40%) and alanine aminotransferase (64%). There were no significant differences in total bilirubin between the adherence groups. Tuberculosis patients with poor adherence showed significantly increased levels of alanine aminotransferase and aspartate aminotransferase levels (p < 0.05). Female patients with poor adherence had high levels of alanine aminotransferase and aspartate aminotransferase.ConclusionThe monitoring of alanine aminotransferase and aspartate aminotransferase in tuberculosis patients should be implemented during the 2nd, 4th, and 6th months of treatment, especially in female patients.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251348228"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171274/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immunoglobulin G4-related ophthalmic disease with orbital deep hemangioma: A case report.","authors":"Huirun Zeng, Xiaolin Peng, Weimin He","doi":"10.1177/03000605251345239","DOIUrl":"10.1177/03000605251345239","url":null,"abstract":"<p><p>Immunoglobulin G4-related ophthalmic disease is an autoimmune condition characterized histologically by dense lymphoplasmacytic infiltration, obliterative phlebitis, and storiform fibrosis. Orbital hemangioma is one of the most common primary orbital tumors in adults. The coexistence of immunoglobulin G4-related ophthalmic disease and orbital hemangioma is extremely rare. This report presents the case of a man in his early 30s diagnosed with immunoglobulin G4-related ophthalmic disease. He was treated with glucocorticoid therapy and gamma knife radiosurgery. Herein, we described the clinical presentation, imaging findings, histopathology, treatment, and outcomes of this rare case to provide a reference for future diagnosis and management.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251345239"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12159463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A novel androgen resistance gene mutation (p.G590W) in complete androgen insensitivity syndrome: Emphasizing the need for early gonadectomy and integrated patient care.","authors":"Hai-Yan Sun, Xu Wang, Li-Xian Wang, Hui Zhang","doi":"10.1177/03000605251350626","DOIUrl":"10.1177/03000605251350626","url":null,"abstract":"<p><p>Complete androgen insensitivity syndrome is a rare 46,XY disorder of sex development caused by mutations in the androgen receptor gene, resulting in androgen resistance despite a normal male karyotype. Individuals with complete androgen insensitivity syndrome typically present with female external genitalia, primary amenorrhea, and a heightened risk of gonadal germ cell tumors. Herein, we report the case of a 30-year-old woman who was diagnosed with complete androgen insensitivity syndrome at 18 years of age during evaluation for primary amenorrhea. Chromosomal analysis revealed a 46,XY karyotype, and imaging confirmed the absence of a uterus and ovaries. Despite medical advice for prophylactic gonadectomy, the patient delayed surgery and later presented with a palpable abdominal mass. Genetic analysis identified a novel hemizygous germline missense mutation, c.1768G>T (p.G590W), in exon 2 of the androgen receptor gene, which was classified as potentially pathogenic based on the American College of Medical Genetics and Genomics criteria. The patient underwent tumor resection followed by four cycles of bleomycin, etoposide, cisplatin chemotherapy regimen for advanced seminoma and has remained disease-free during follow-up. This case underscores the importance of genetic analysis, early prophylactic gonadectomy, and multidisciplinary care in managing complete androgen insensitivity syndrome to mitigate tumor risk and optimize outcomes.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251350626"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12188037/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accessory mitral valve tissue causing left ventricular outflow tract obstruction associated with subaortic membrane and aortic sinus aneurysm: A case report and literature review.","authors":"Jing Xu, Mei Zhang, Nan Zheng, Daoning Guo, Yunfeng Wei","doi":"10.1177/03000605251348230","DOIUrl":"10.1177/03000605251348230","url":null,"abstract":"<p><p>Accessory mitral valve tissue is a rare congenital cardiac anomaly that can lead to left ventricular outflow tract obstruction. We present the case of an older female patient with accessory mitral valve tissue, a subaortic membrane, an unruptured aneurysm of the aortic sinus, and left ventricular outflow tract obstruction. Successful excision of the accessory mitral valve tissue and repair of the aortic sinus were performed. Postoperative echocardiography showed complete removal of the subaortic membrane, with a residual accessory mitral valve tissue (5 mm). Color Doppler imaging revealed a significant reduction in mosaic flow signals in the left ventricular outflow tract, with the peak blood flow velocity decreasing to 1.6 m/s. The postoperative course was uneventful, and the patient was followed up with echocardiography at 3 days, 5 days, 1 month, 3 months, and 6 months after the surgery. Accessory mitral valve tissue is a rare congenital defect frequently associated with other cardiovascular congenital malformations. This report also provides a comprehensive clinical review of accessory mitral valve tissue, covering anatomical classification, associated cardiac anomalies, pathophysiology, diagnostic approaches, and treatment strategies to offer an improved clinical understanding of the condition.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251348230"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12171269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144284937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of the combined use of computed tomography perfusion imaging and blood pressure levels for the prognosis of patients with acute ischemic stroke.","authors":"Yunxia Qi, Bolin Liu, Yiying Wu, Yifeng Peng","doi":"10.1177/03000605251349927","DOIUrl":"10.1177/03000605251349927","url":null,"abstract":"<p><p>ObjectiveThis study aimed to use computed tomography perfusion imaging to investigate the correlation between blood pressure at onset and prognosis in patients with acute ischemic stroke and collateral circulation. It also aimed to verify the value of using blood pressure levels along with computed tomography perfusion imaging for predicting the prognosis of patients with acute ischemic stroke.MethodsThis retrospective study included 237 patients with acute ischemic stroke. Patients were divided into good prognosis group and poor prognosis group based on the National Institute of Health Stroke Scale scores after clinical discharge. All patients underwent computed tomography perfusion imaging, and image post-processing was performed. Comparison of clinical characteristics, blood pressure levels, and computed tomography perfusion imaging measurements was performed between the two groups. Univariate and multivariate logistic regression analyses and receiver operating characteristic curve analyses were performed for the collected clinical variables.ResultsOf the 237 recruited patients (aged 67.54 ± 7.75 years; 103 males), 151 had a good prognosis. There were no significant differences in age, systolic blood pressure levels, and alcohol consumption pattern as well as the presence of diabetes, myocardial infarction, coronary atherosclerotic disease, and atrial fibrillation between the good and poor prognosis groups (P > 0.05). There were significant differences in terms of sex distribution and diastolic blood pressure levels between the two groups (P = 0.028 and P < 0.05, respectively). Binary logistic regression analysis revealed that patient prognosis was positively correlated with diastolic blood pressure levels, cerebral blood flow <30%, and mismatch ratio (P < 0.05). Partial correlation analysis revealed a positive correlation between blood pressure levels and cerebral blood flow <30% and mismatch ratio (P < 0.05). Receiver operating characteristic curve analysis revealed that the areas under the blood pressure, cerebral blood flow, mismatch, and combined prognostic value curves were 0.657, 0.683, 0.693, and 0.711, respectively. The sensitivity and specificity were 69.8%, 46.5%, 46.5%, and 57.4% and 60.9%, 90.1%, 95.4%, and 92.1%, respectively.ConclusionThere is a correlation between blood pressure levels and prognosis in patients with acute ischemic stroke; however, blood pressure does not affect prognosis by influencing the collateral circulation status in the ischemic area. The combined use of blood pressure levels, cerebral blood flow <30%, and mismatch ratio can improve the prognosis of patients with acute ischemic stroke.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251349927"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12205207/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505963","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unilateral anterior choroidal artery infarction presenting with a temporary stupor.","authors":"Dandan Yu, Xian Zhang, Wei Tang","doi":"10.1177/03000605251345965","DOIUrl":"10.1177/03000605251345965","url":null,"abstract":"<p><p>A 73-year-old woman presented with a temporary stupor and right hemiplegia. Brain magnetic resonance imaging revealed acute infarction of the anterior choroidal artery. The clinical features associated with acute anterior choroidal artery infarction typically include hemiparesis, hemihypesthesia, and hemianopsia. However, our patient presented with a temporary stupor, which is a rare manifestation of anterior choroidal artery infarction.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251345965"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12152391/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frailty and diabetes: A study in patients with proliferative diabetic retinopathy.","authors":"Jie Li, Kai Wang, Bei Yuan, Na Chen, Yueling Zhang","doi":"10.1177/03000605251347414","DOIUrl":"10.1177/03000605251347414","url":null,"abstract":"<p><p>ObjectiveThis study aimed to investigate the prevalence of frailty and its influencing factors among older individuals diagnosed with proliferative diabetic retinopathy, a predominant complication of diabetes that frequently leads to visual impairment. Additionally, this study aimed to identify key demographic, socioeconomic, and clinical determinants linked to frailty within this specific patient population.MethodsThis multicenter cross-sectional study enrolled 600 patients with proliferative diabetic retinopathy (aged ≥60 years) from two tertiary hospitals in Baoding (February to August 2024). The patients were categorized into frailty (n = 345) and nonfrailty (n = 255) groups using standardized criteria. The data collected included demographic characteristics, medical history, frailty assessment (frailty phenotype), and social support rating scale scores.ResultsThe frailty prevalence among the participants was 57.46%. Significant between-group differences (<i>P</i> < 0.05) were observed in diabetes duration, social support, monthly income, bilateral eye involvement, living alone, and having ≥3 comorbidities. Frailty scale scores were inversely correlated with social support (r = -0.42, <i>P</i> < 0.001). Multivariate analysis identified the following independent predictors: low income (odds ratio = 2.34; 95% confidence interval: 1.67-3.28), solitary living (odds ratio = 1.89; 95% confidence interval: 1.32-2.71), multiple complications (odds ratio = 3.12; 95% confidence interval: 2.18-4.46), prolonged diabetes (odds ratio = 1.45/year; 95% confidence interval: 1.32-1.59), and poor social support (odds ratio = 0.92/point; 95% confidence interval: 0.89-0.95).ConclusionsOver half of the older patients with proliferative diabetic retinopathy exhibit frailty, which is significantly associated with socioeconomic disadvantages, clinical severity, and inadequate social support. These findings highlight the need for comprehensive geriatric assessment in proliferative diabetic retinopathy management.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251347414"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12152397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144258211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymph node metastasis of grade 1 neuroendocrine tumor from rectal mixed neuroendocrine non-neuroendocrine neoplasm: A case report.","authors":"Taek-Gu Lee, Ki Bae Kim, Jun Su Lee, Chang Gok Woo, Seung-Myoung Son","doi":"10.1177/03000605251345907","DOIUrl":"10.1177/03000605251345907","url":null,"abstract":"<p><p>Mixed neuroendocrine non-neuroendocrine neoplasms of the gastrointestinal tract are rare, with only a few cases documented in the literature. In particular, there are no reports of a rectal mixed neuroendocrine non-neuroendocrine neoplasm with regional lymph node metastasis of the neuroendocrine tumor component. Here, we present the case of a man in his early 70s with an incidental finding of multiple colonic polyps during a routine colonoscopy, including a 0.9-cm sessile polyp in the rectum. Repeat colonoscopy was performed for endoscopic mucosal resection. Histopathological examination revealed a biphasic tumor comprising a well-differentiated adenocarcinoma and a grade 1 neuroendocrine tumor, leading to a diagnosis of rectal mixed neuroendocrine non-neuroendocrine neoplasm. Because the adenocarcinoma component had invaded the submucosa and involved the resection margin, an ultralow anterior resection was performed. Notably, postoperative pathological analysis revealed metastasis of the neuroendocrine tumor component to a regional lymph node, an unusual finding not previously reported in the literature. Despite this, the patient remained recurrence-free for 2 years without adjuvant therapy. To the best of our knowledge, this is the first such case to be reported in the literature. Given the limited understanding of mixed neuroendocrine non-neuroendocrine neoplasms, particularly cases with low-grade neuroendocrine components, further case accumulation is necessary to develop standardized treatment guidelines.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 6","pages":"3000605251345907"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12144341/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144225633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}