Journal of International Medical Research最新文献_第6页

Spontaneous ovarian hyperstimulation syndrome mimicking ovarian cancer in a nonpregnant woman: A case report and literature review. 自发性卵巢过度刺激综合征模仿卵巢癌在非怀孕妇女：一个病例报告和文献复习。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-04-01 Epub Date: 2025-04-28 DOI: 10.1177/03000605251332908

Setare Akhavan, Morteza Daraei, Faeze Salahshour, Mina Sadat Mosavat

{"title":"Spontaneous ovarian hyperstimulation syndrome mimicking ovarian cancer in a nonpregnant woman: A case report and literature review.","authors":"Setare Akhavan, Morteza Daraei, Faeze Salahshour, Mina Sadat Mosavat","doi":"10.1177/03000605251332908","DOIUrl":"https://doi.org/10.1177/03000605251332908","url":null,"abstract":"Spontaneous ovarian hyperstimulation syndrome is an extremely rare condition, especially in nonpregnant women who do not exhibit exogenous ovarian stimulation. Herein, we present a case of spontaneous ovarian hyperstimulation syndrome in a 28-year-old nonpregnant woman who presented with life-threatening multiorgan dysfunction. Initial imaging studies and tumor marker assessment suggested the presence of a malignant ovarian tumor, posing substantial diagnostic challenges. The patient underwent emergency surgery due to severe hemorrhagic shock. Intraoperative findings revealed irregular and deformed ovaries; however, histologic examination showed luteinizing hemorrhagic cysts, leading to a diagnosis of spontaneous ovarian hyperstimulation syndrome. This case highlights the importance of considering spontaneous ovarian hyperstimulation syndrome in the differential diagnosis of ovarian enlargement with ascites, even in the absence of pregnancy or ovarian stimulation. It also underscores the critical role of expert radiological interpretation in such complex cases.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251332908"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12038210/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143999834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Identifying risk factors for recurrent mild ischemic stroke and high-risk population characteristics: A 1-year follow-up study. 确定复发性轻度缺血性卒中的危险因素和高危人群特征：一项为期1年的随访研究

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-04-01 Epub Date: 2025-04-27 DOI: 10.1177/03000605251332585

Shangmeng Huang, Zhengyu Wu, Wenbin Lan, Junqing Huang, Huijuan Wan, Dewen Wang, Jin Han Chen

{"title":"Identifying risk factors for recurrent mild ischemic stroke and high-risk population characteristics: A 1-year follow-up study.","authors":"Shangmeng Huang, Zhengyu Wu, Wenbin Lan, Junqing Huang, Huijuan Wan, Dewen Wang, Jin Han Chen","doi":"10.1177/03000605251332585","DOIUrl":"https://doi.org/10.1177/03000605251332585","url":null,"abstract":"ObjectiveThis observational study examined the risk factors associated with recurrence in patients with mild ischemic stroke and determined the characteristics of high-risk groups.MethodsA total of 656 patients hospitalized for mild ischemic stroke were monitored for 1 year. Statistical analyses, including odds ratio calculations and K-means clustering, were conducted to examine risk factors for recurrence and the characteristics of high-risk groups.ResultsAfter 1 year of follow-up, 99 patients experienced recurrent mild ischemic stroke, resulting in a recurrence rate of 15.09%. The analysis revealed several significant risk factors, including type 2 diabetes mellitus, atrial fibrillation, smoking and alcohol consumption, carotid artery stenosis, cerebral vascular stenosis, and multiple lesions. Propensity score matching confirmed these associations, and K-means clustering revealed that older males with type 2 diabetes mellitus and hypertension were likely to be in the high-risk group.ConclusionsHealthcare professionals should focus on tailored treatment and prevention strategies for high-risk patients, prioritizing the management of the abovementioned risk factors to reduce recurrence and improve outcomes.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251332585"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12035232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Outcome of optic disc capillary hemangioma following intravitreal ranibizumab injection: A case report. 玻璃体内注射雷尼单抗治疗视盘毛细血管瘤1例。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-04-01 Epub Date: 2025-04-11 DOI: 10.1177/03000605251328621

Miao Hao, Fengjiao Li, Suzhen Zhao, Yalin Wang, Shengnan Ma, Weiyan Zhou

{"title":"Outcome of optic disc capillary hemangioma following intravitreal ranibizumab injection: A case report.","authors":"Miao Hao, Fengjiao Li, Suzhen Zhao, Yalin Wang, Shengnan Ma, Weiyan Zhou","doi":"10.1177/03000605251328621","DOIUrl":"https://doi.org/10.1177/03000605251328621","url":null,"abstract":"Optic disc capillary hemangiomas, a rare capillary hamartoma that often invades optic nerve fibers and disc plaque bundles, have been a therapeutic challenge for ophthalmologists in recent years due to their unique location. A woman in her early 50s presented with blurred vision in the right eye for 2 days. On ocular examination, her best-corrected visual acuity was 20/340 in the right eye. Wide-field fundus imaging revealed a red mass on the temporal side of the optic disc. Optical coherence tomography revealed macular edema. The diagnosis was optic disc capillary hemangioma. Subsequently, 0.5 mg ranibizumab was intravitreally injected into the right eye once monthly, for a total of two injections. The patient was re-examined at 15 days, 50 days, and 21 months after the first operation. The patient's postoperative best-corrected visual acuity improved to 20/60, and macular edema and exudation were reduced in the short term compared with those in the previous period; however, the tumor did not change significantly. The anti-vascular endothelial growth factor agent ranibizumab is effective in treating optic disc capillary hemangiomas.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 4","pages":"3000605251328621"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12033708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143986445","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Management of adrenocortical adenoma in systemic sclerosis: A case report. 系统性硬化症肾上腺皮质腺瘤的处理：1例报告。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-04-01 Epub Date: 2025-04-02 DOI: 10.1177/03000605251326822

Zongyan Luo, Yuanlong Shi, Jinye Yang, Yuanpeng Duan, Qiao Wang, Can Li, Sinan Yang, Bo Peng, Kun Zhang, Libo Yang, Bin Zhao, Chengwei Bi

引用次数: 0

Recurrent acute myocardial infarction associated with calcified pseudoaneurysm: A case analysis. 复发性急性心肌梗死伴钙化假性动脉瘤1例分析。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-03-01 Epub Date: 2025-03-13 DOI: 10.1177/03000605251325180

Zhi-Ling Gao, Ping Xie, Xing Zhou, Yan-Ling Li

引用次数: 0

Assessing the diagnostic utility of cardiopulmonary exercise testing in evaluating coronary artery disease. 评估心肺运动试验在评估冠状动脉疾病中的诊断价值。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-03-01 Epub Date: 2025-03-13 DOI: 10.1177/03000605251325170

Jianhua Xie, Yuan Liang, Xiaobo Huang, Yuxue Qin, Hai Huang, Jianxiong Liu

{"title":"Assessing the diagnostic utility of cardiopulmonary exercise testing in evaluating coronary artery disease.","authors":"Jianhua Xie, Yuan Liang, Xiaobo Huang, Yuxue Qin, Hai Huang, Jianxiong Liu","doi":"10.1177/03000605251325170","DOIUrl":"10.1177/03000605251325170","url":null,"abstract":"ObjectiveThis retrospective study aimed to investigate the correlation between the cardiopulmonary exercise test (CPET) and the severity of coronary stenosis (SYNTAX score) in patients with stable coronary artery disease (SCAD), thereby assessing CPET's diagnostic value.MethodsWe classified 220 patients who underwent coronary angiography into coronary heart disease (CHD) and non-CHD groups based on stenosis severity. Patients with SCAD were categorized into mild, moderate, and severe groups by the SYNTAX score. CPET was performed, and data on the general information, serological indicators, and echocardiographic parameters were collected. CPET parameters included oxygen uptake related to the work rate (△VO2/△WR), peak metabolic equivalent (Peak Mets), anaerobic threshold (AT), peak oxygen consumption per kilogram (PVO2/kg), and metabolic equivalent at anaerobic threshold (Met@AT).ResultsPatients without SCAD demonstrated significantly higher CPET parameters than those with SCAD. The CPET parameters varied significantly across severity groups in the SCAD group, with the mild group exhibiting higher values than the moderate and severe groups. No significant differences were observed in the baseline data between the groups or among patients with varying numbers of lesion branches.ConclusionCPET parameters demonstrated a significant negative correlation with the SYNTAX score in patients with SCAD, indicating its potential clinical value in assessing the severity of coronary stenosis and diagnosing SCAD.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251325170"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907529/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case study: Acute plasmoblastic leukemia presentation following effective haploidentical hematopoietic stem cell transplantation therapy. 个案研究：急性浆母细胞白血病的表现后，有效的单倍体造血干细胞移植治疗。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-03-01 Epub Date: 2025-03-28 DOI: 10.1177/03000605251326804

Azat Karabekov, Madina Abdirgalieva, Aigerim Najipova, Vadim Kemaykin, Olga Kolesnikova, Ruzal Vildanova, Almira Manatova, Zhuldyz Kuanysh

{"title":"Case study: Acute plasmoblastic leukemia presentation following effective haploidentical hematopoietic stem cell transplantation therapy.","authors":"Azat Karabekov, Madina Abdirgalieva, Aigerim Najipova, Vadim Kemaykin, Olga Kolesnikova, Ruzal Vildanova, Almira Manatova, Zhuldyz Kuanysh","doi":"10.1177/03000605251326804","DOIUrl":"10.1177/03000605251326804","url":null,"abstract":"Plasma cell leukemia is a rare and aggressive malignancy characterized by monoclonal gammopathy and the presence of circulating plasma cells in the peripheral blood. Therapeutic strategies for plasma cell leukemia remain undefined, with treatments primarily borrowed from those used in multiple myeloma. The first-line treatment typically involves a combination of a proteasome inhibitor, an immunomodulatory agent, steroids, and/or anthracyclines and alkylators within an intensive chemotherapy regimen. Following this, consolidation with autologous hematopoietic stem cell transplantation is offered to eligible patients, followed by maintenance therapy. For patients ineligible for autologous hematopoietic stem cell transplantation, allogeneic hematopoietic stem cell transplantation is considered a viable alternative. Given the challenges in securing a fully human leukocyte antigen-matched donor, haploidentical hematopoietic stem cell transplantation serves as a potential salvage therapy, as demonstrated in the clinical case presented. This article presents the case of a female patient in her 50s diagnosed with plasma cell leukemia who, following unsuccessful autologous hematopoietic stem cell mobilization, underwent haploidentical hematopoietic stem cell transplantation from her son, resulting in complete donor chimerism and a favorable response.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251326804"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11954571/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143728756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Embolic stroke complicating left ventricular thrombus in Takotsubo syndrome: A case report. Takotsubo 综合征左心室血栓并发栓塞性中风：病例报告。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-03-01 Epub Date: 2025-03-22 DOI: 10.1177/03000605251326764

Jingshu Lei, Lina Wang, Ningning Yin, Zhiqi Zhang

引用次数: 0

Evaluation of the effects of regulatory T cells on survival outcomes in patients with acute leukemia who developed febrile neutropenia. 评估调节性 T 细胞对发热性中性粒细胞减少症急性白血病患者生存结果的影响。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-03-01 Epub Date: 2025-03-12 DOI: 10.1177/03000605241276482

Sebnem Calik, Oktay Bilgir, İsmail Demir, Selma Tosun, Yeliz Özdemir

{"title":"Evaluation of the effects of regulatory T cells on survival outcomes in patients with acute leukemia who developed febrile neutropenia.","authors":"Sebnem Calik, Oktay Bilgir, İsmail Demir, Selma Tosun, Yeliz Özdemir","doi":"10.1177/03000605241276482","DOIUrl":"10.1177/03000605241276482","url":null,"abstract":"ObjectivesAcute leukemia often leads to severe complications such as febrile neutropenia. Mortality rates remain high, underscoring the need for novel prognostic markers. Regulatory T cells (Tregs) have not been extensively studied in this context.MethodsThis prospective observational, single-center study included 114 patients diagnosed with acute leukemia. Tregs percentages were measured using flow cytometry. Statistical analyses involved logistic regression to identify factors significantly associated with survival.ResultsOf the 114 patients, 78 recovered, while 36 died. The median Treg percentages were 5.9% in patients under 65 years and 5.38% in those 65 and older. A lower percentage of Tregs was associated with higher mortality in the older group (p = 0.04). Multivariate analysis highlighted the presence of comorbidities, documented infections, and day seven C-reactive protein levels as significant predictors of survival.ConclusionThis study supports the importance of monitoring chronic diseases and infection foci alongside traditional markers like C-reactive protein. Future research should explore the mechanistic roles of Tregs in immunosuppression and survival in this vulnerable population.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605241276482"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905019/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Multiple cardioembolic attacks with a huge ventricular thrombus in dilated cardiomyopathy: A case report and comprehensive review. 扩张型心肌病伴巨大心室血栓的多重心栓子发作：1例报告并综合复习。

IF 1.4 4区医学

Journal of International Medical Research Pub Date : 2025-03-01 Epub Date: 2025-03-13 DOI: 10.1177/03000605251324593

Maziar Moayerifar, Mani Moayerifar, Mahboobeh Gholipour, Pirouz Samidoust, Selvana Poursadrolah, Golshan Ghasemzadeh, Mahsa Radmoghadam

{"title":"Multiple cardioembolic attacks with a huge ventricular thrombus in dilated cardiomyopathy: A case report and comprehensive review.","authors":"Maziar Moayerifar, Mani Moayerifar, Mahboobeh Gholipour, Pirouz Samidoust, Selvana Poursadrolah, Golshan Ghasemzadeh, Mahsa Radmoghadam","doi":"10.1177/03000605251324593","DOIUrl":"10.1177/03000605251324593","url":null,"abstract":"Left ventricular thrombus is one of the major complications of dilated cardiomyopathy. Although the presence of a cardiac thrombus is a major risk factor for embolization, several probable conditions, the connection of which is not thoroughly studied, such as gout disease and methamphetamine abuse, are also possible causes. We present the case report of a male in his early 40s with a history of alcohol and methamphetamine abuse, gout, and dilated cardiomyopathy, experiencing multiple ischemic attacks, including acute limb ischemia, dysarthria, and renal infarct. Echocardiography revealed a large clot in the left ventricle. The patient received heparin at a rate of 1000 units/hour, followed by warfarin at 10 mg/day, and probenecid at 500 mg/day. The thrombus resolved upon anticoagulant therapy, with improvement in the patient's symptoms. Left ventricular thrombus formation in dilated cardiomyopathy is influenced by many factors, including drug toxicity (for instance, methamphetamine), uric acid levels, and N-terminal precursor B-type natriuretic peptide. The thrombus can cause cardioembolic attacks in multiple sites, and the choice for emergent therapy is an oral anticoagulant, which may improve the ejection fraction. However, certain aspects related to cardiac thrombosis and embolization risk still warrant more comprehensive studies.","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"53 3","pages":"3000605251324593"},"PeriodicalIF":1.4,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907587/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0