Journal of International Medical Research最新文献

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Success rate of acceleromyographic neuromuscular monitoring based on the depth of anesthesia at the time of sugammadex antagonism: a randomized controlled trial. 糖玛德拮抗时基于麻醉深度的加速肌图神经肌肉监测的成功率:一项随机对照试验。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241305474
Hwang-Ju You, Seok-Jin Lee, Ji-Yoon Jung, Sung-Ae Cho, Woojin Kwon, Jin-Bum Kim, Tae-Yun Sung
{"title":"Success rate of acceleromyographic neuromuscular monitoring based on the depth of anesthesia at the time of sugammadex antagonism: a randomized controlled trial.","authors":"Hwang-Ju You, Seok-Jin Lee, Ji-Yoon Jung, Sung-Ae Cho, Woojin Kwon, Jin-Bum Kim, Tae-Yun Sung","doi":"10.1177/03000605241305474","DOIUrl":"10.1177/03000605241305474","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to compare the success of non-normalized acceleromyographic neuromuscular monitoring and recovery profiles based on the depth of anesthesia at the time of sugammadex administration.</p><p><strong>Methods: </strong>Patients undergoing general anesthesia were prospectively and randomly allocated to two groups. In the BIS60 group, sugammadex was administered when there was a bispectral index (BIS) <60 and anesthesia was maintained until a train-of-four ratio ≥1.0 was obtained, whereas in the BIS70 group, anesthesia was stopped at the completion of surgery, sugammadex was administered when the BIS was >70, and the recovery of neuromuscular function was monitored. The recovery profile and the incidence of emergence agitation of the two groups were compared.</p><p><strong>Results: </strong>The success rate of neuromuscular monitoring was significantly higher for the BIS60 group than for the BIS70 group (100% <i>vs</i>. 37.5%, respectively). The time taken for recovery for the two groups was comparable. The incidence of emergence agitation was significantly lower in the BIS60 group than in the BIS70 group (23.3% <i>vs</i>. 56.3%, respectively).</p><p><strong>Conclusion: </strong>After the administration of sugammadex, the maintenance of anesthesia until the full recovery of neuromuscular function increases the success rate of neuromuscular monitoring without delaying recovery and reduces the risk of emergence agitation.<b>Clinical trial registration:</b> CRIS registration number KCT0007899 (https://cris.nih.go.kr/).</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241305474"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Epidemiology of asymptomatic peptic ulcer disease diagnosed during screening endoscopy in patients with cirrhosis. 肝硬化患者内镜筛查诊断无症状性消化性溃疡的流行病学。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241305258
Girma Deshimo Lema, Enguday Demeke Gebeyaw
{"title":"Epidemiology of asymptomatic peptic ulcer disease diagnosed during screening endoscopy in patients with cirrhosis.","authors":"Girma Deshimo Lema, Enguday Demeke Gebeyaw","doi":"10.1177/03000605241305258","DOIUrl":"10.1177/03000605241305258","url":null,"abstract":"<p><strong>Objective: </strong>Asymptomatic peptic ulcer disease (PUD) is frequently overlooked in patients with cirrhosis, who are at increased risk for gastrointestinal complications that can lead to increased morbidity and mortality. We aimed to determine the prevalence and associated factors of asymptomatic PUD identified during screening endoscopy in patients with cirrhosis.</p><p><strong>Methods: </strong>We conducted a retrospective cross-sectional study among patients with cirrhosis at St. Paul's Hospital Millennium Medical College in Ethiopia. Data were collected using a structured questionnaire from patients' medical charts. A logistic regression model was used to identify predictors of peptic ulcer.</p><p><strong>Results: </strong>This study included 296 patients, revealing that 19.6% had PUD (95% confidence interval: 13.5-26.4). Significant associations were found between peptic ulcer and <i>Helicobacter pylori</i> infection, moderate and heavy alcohol consumption, and Child-Pugh class C cirrhosis.</p><p><strong>Conclusion: </strong>We found that patients with liver cirrhosis are more likely to have asymptomatic peptic ulcers. Asymptomatic PUD was linked to <i>H. pylori</i> infection, greater alcohol consumption, and Child-Pugh class C liver disease, highlighting the need for targeted prevention and management strategies to reduce morbidity in patients with cirrhosis, such as eradication therapy for <i>H. pylori</i> and counseling on alcohol use.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241305258"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653440/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142846716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adenoid cystic carcinoma in the nasolacrimal duct: a case report. 鼻泪管腺样囊性癌1例。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241310843
Seung-Myoung Son, Chang Gok Woo
{"title":"Adenoid cystic carcinoma in the nasolacrimal duct: a case report.","authors":"Seung-Myoung Son, Chang Gok Woo","doi":"10.1177/03000605241310843","DOIUrl":"10.1177/03000605241310843","url":null,"abstract":"<p><p>Adenoid cystic carcinoma (ACC) rarely occurs in the nasolacrimal duct (NLD), and when it does, it has nonspecific manifestations. To the best of our knowledge, one case of ACC in the NLD has been reported in the literature. Herein, we report a second case of ACC in the left NLD, concerning a man in his late 60s. He presented with epiphora, and swelling and pain below the left medial canthus. Nasal endoscopy revealed bulging of the lateral wall in the left nasal cavity, with an intact nasal mucosa. Paranasal sinus computed tomography showed an enhancing mass at the epicenter of the left NLD, involving the maxillary sinus, inferior turbinate, and nasal cavity, with bony destruction. The patient underwent superomedial maxillectomy. The pathology was high-grade ACC. Despite undergoing five rounds of postoperative radiotherapy, the ACC recurred 11 months after the operation. Early identification is critical for reducing the morbidity and mortality of patients with ACC in the NLD.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241310843"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11682585/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characteristics and outcomes of patients with Guillain-Barré syndrome who were admitted to the intensive care unit: a retrospective observational study. 入住重症监护室的格林-巴罗综合征患者的特征和结局:一项回顾性观察性研究。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241306655
Samah Alqahtani, Hasan M Al-Dorzi, Hatim Arishi, Ahmad Peeran, Felwa Bin Humaid, Farhan Zayed Alenezi, Jesna Jose, Musharaf Sadat, Naser Alotaibi, Yaseen M Arabi
{"title":"Characteristics and outcomes of patients with Guillain-Barré syndrome who were admitted to the intensive care unit: a retrospective observational study.","authors":"Samah Alqahtani, Hasan M Al-Dorzi, Hatim Arishi, Ahmad Peeran, Felwa Bin Humaid, Farhan Zayed Alenezi, Jesna Jose, Musharaf Sadat, Naser Alotaibi, Yaseen M Arabi","doi":"10.1177/03000605241306655","DOIUrl":"10.1177/03000605241306655","url":null,"abstract":"<p><strong>Objective: </strong>To evaluate characteristics and outcomes in critically ill patients with Guillain-Barré syndrome (GBS).</p><p><strong>Methods: </strong>Consecutive adults with GBS who required intensive care unit (ICU) admission at a tertiary-care hospital between 1999 and 2020 were enrolled into this retrospective cohort study. Demographics, clinical data and patient outcomes were compared between patients who did or did not receive mechanical ventilation (MV).</p><p><strong>Results: </strong>During the study period, the number of ICU admissions gradually rose from approximately 900 to 3000 annually. Forty-three patients had GBS and were included, of whom, 27 (62.8%) received MV for a median of 13 days. The MV group stayed longer in the ICU (median, 26 versus 6 days) and in the hospital (median, 120 versus 39 days) than the non-MV group. Most patients in the MV group (22 [81.5%]) required tracheostomy. At maximum follow-up, Hughes Functional Grading scores were 0 (full recovery) in 11 patients (25.5%), 1-3 in 18 (41.8%), 4-5 in 12 (27.9%), and 6 (death) in two (4.6%, both in the MV group), with higher median Hughes score in the MV group (3 versus 0.5). Complications during ICU and hospital stay included: veinous thromboembolism in five (11.6%), gastrointestinal bleeding in three (7.0%), bacteremia in five (11.6%), bedsore in one (2.3%), and GBS-treatment side effects in four (9.4%) patients; all of these complications occurred within the MV group.</p><p><strong>Conclusions: </strong>GBS was an uncommon reason for ICU admission. The findings highlight significant morbidity with GBS, particularly among patients who need MV.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241306655"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11683809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142885812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Haematometra arising from multiple abortions: a comprehensive case report. 多胎流产致血肿一例综合报道。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241304576
Georges Yared, Ali Younis, Khodor Al Hajj, Charlotte El Hajjar, Wardah Alakrah, Hamza Nakib, Christopher Massaad, Kariman Ghazal
{"title":"Haematometra arising from multiple abortions: a comprehensive case report.","authors":"Georges Yared, Ali Younis, Khodor Al Hajj, Charlotte El Hajjar, Wardah Alakrah, Hamza Nakib, Christopher Massaad, Kariman Ghazal","doi":"10.1177/03000605241304576","DOIUrl":"10.1177/03000605241304576","url":null,"abstract":"<p><p>Haematometra, a rare and delayed complication, can emerge following medical termination of pregnancy, also known as 'postabortal post-caesarean syndrome' or 'redo syndrome'. Treatment requires the immediate evacuation of both liquid and clotted blood for quick resolution, followed by administration of an oxytocic agent to ensure complete recovery. This current report describes a female patient in her mid-30s who presented with colicky lower abdominal pain following a medically-induced abortion at 10 weeks. The case underscores the critical need for vigilance in detecting haematometra after abortion or caesarean delivery. Prompt recognition through symptoms and ultrasound, followed by immediate treatment, is essential to prevent severe complications such as infertility and ensure ongoing reproductive health.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241304576"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626672/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interventional closure in the treatment of cardiac cavity perforation caused by pericardial puncture: a case report. 介入封闭治疗心包穿刺致心腔穿孔1例。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241304595
Yue Sun, Jingzhe Han, Hongshan Kang
{"title":"Interventional closure in the treatment of cardiac cavity perforation caused by pericardial puncture: a case report.","authors":"Yue Sun, Jingzhe Han, Hongshan Kang","doi":"10.1177/03000605241304595","DOIUrl":"10.1177/03000605241304595","url":null,"abstract":"<p><p>Interventional treatment for left ventricular free wall or apex perforation is rarely reported. This current case report describes a male patient in his 70 s with left ventricular perforation caused by pericardiocentesis that was successfully treated through interventional means. The patient was admitted to the hospital due to chest pain accompanied by asthmatic breathing difficulties that had lasted for the previous 10 h. Two years previously, the patient had a history of thymoma, during which pericardial effusion was discovered, leading to multiple hospitalizations for pericardial fluid aspiration. On the 10th day of admission, a chest computed tomography scan confirmed iatrogenic left ventricular apical perforation and haemorrhagic anaemia, after which interventional transcatheter left ventricular perforation sealing was performed. Postoperatively, the patient was conscious, with stable vital signs and no particular discomfort. The successful implementation of this interventional procedure suggests a new minimally invasive solution for treating left ventricular perforation caused by pericardiocentesis or interventional catheterization.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241304595"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11626708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142794815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Retrospective cohort study of fluctuations in emergency department visits for nonspecific back and neck pain during the COVID-19 pandemic. COVID-19大流行期间非特异性背部和颈部疼痛急诊就诊波动的回顾性队列研究
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241302010
Nissim Ohana, Yuval Baruch, Alex Tavdi, Ezequiel Palmanovich, Daniel Benharroch, Itzhak Engel, Eyal Yaacobi
{"title":"Retrospective cohort study of fluctuations in emergency department visits for nonspecific back and neck pain during the COVID-19 pandemic.","authors":"Nissim Ohana, Yuval Baruch, Alex Tavdi, Ezequiel Palmanovich, Daniel Benharroch, Itzhak Engel, Eyal Yaacobi","doi":"10.1177/03000605241302010","DOIUrl":"10.1177/03000605241302010","url":null,"abstract":"<p><strong>Objective: </strong>We examined fluctuations in emergency department (ED) visits for nonspecific back and neck pain during the COVID-19 pandemic and explored potential contributing factors.</p><p><strong>Methods: </strong>This retrospective cohort study included patients who presented to the ED with nonspecific back and neck pain between January 2019 and December 2021. Demographic data, visit frequencies, and clinical outcomes were analyzed to assess the impact of the pandemic on visit patterns.</p><p><strong>Results: </strong>A total of 1245 ED visits were recorded. Visits decreased by 30% during the peak of the pandemic, with a gradual return to baseline by mid-2021. No significant changes in patient demographics or clinical outcomes were noted during the pandemic. However, a proportional increase in neck pain visits was observed.</p><p><strong>Conclusions: </strong>The observed decline in visits may be linked to pandemic-related concerns, such as fear of exposure in the hospital and reduced activities. The increased neck pain visits highlights the potential influence of pandemic-related stress and lifestyle changes. Visit patterns rebounded as the pandemic eased, indicating a temporary decrease unrelated to condition severity. The COVID-19 pandemic temporarily affected ED visits for nonspecific back and neck pain. Further research is needed to explore the long-term effects of the pandemic on health care utilization.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241302010"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622333/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neuropsychiatric symptoms in Parkinson's disease: review of data from the Arab world. 帕金森病的神经精神症状:来自阿拉伯世界的数据回顾。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-12-01 DOI: 10.1177/03000605241304646
Alfred Chabbouh, Hassan Khalil, Chafic Abboud, Antoine Sader, Rita Khoury
{"title":"Neuropsychiatric symptoms in Parkinson's disease: review of data from the Arab world.","authors":"Alfred Chabbouh, Hassan Khalil, Chafic Abboud, Antoine Sader, Rita Khoury","doi":"10.1177/03000605241304646","DOIUrl":"10.1177/03000605241304646","url":null,"abstract":"<p><p>Neuropsychiatric symptoms in Parkinson's disease (PD) are common, underrecognized, and impact patients' quality of life. Research around this topic is scarce in the Arab world. The aim of this comprehensive narrative review was to examine available evidence and discusses its strengths and limitations. The PubMed and Embase databases were searched using relevant keywords for studies published between 2000 and 2023. A total of 10 epidemiological and three assessment tool validation studies of neuropsychiatric symptoms in PD, conducted in the 22 Arab countries, were included. Only four Arab countries contributed to the 10 epidemiological studies found. Egypt provided the largest number of patients. Prevalence rates of neuropsychiatric symptoms in PD were heterogenous. Three studies relied on the Non-Motor Symptom Scale to estimate prevalence. Three studies used validated screening tools for dementia. Five studies used specific screening tools for depression, while two used the Diagnostic and Statistical Manual of mental disorders, fourth edition (DSM-IV) diagnostic criteria for depression. No appropriate and validated tool is available to assess for apathy. The generalizability of the findings is limited and recommendations for future studies are provided.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 12","pages":"3000605241304646"},"PeriodicalIF":1.4,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11653321/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142837188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HPV infection status among women of all ages in Jinshan District, Shanghai. 上海市金山区各年龄段女性的 HPV 感染情况。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-11-01 DOI: 10.1177/03000605241291754
Chen Shanshan, Chen Jing, Xiao Tao
{"title":"HPV infection status among women of all ages in Jinshan District, Shanghai.","authors":"Chen Shanshan, Chen Jing, Xiao Tao","doi":"10.1177/03000605241291754","DOIUrl":"10.1177/03000605241291754","url":null,"abstract":"<p><strong>Objective: </strong>We explored the prevalence of human papillomavirus (HPV) infection among women in Jinshan District, Shanghai.</p><p><strong>Methods: </strong>We analyzed all HPV testing samples sent from our unit between December 2023 and April 2024. We reported the HPV prevalence overall, by age, and by subtype.</p><p><strong>Results: </strong>In total, 3788 women aged 16 to 90 years had HPV test results. The prevalence of infection with any HPV subtype was 17.9%. The HPV prevalence by age group was: ≤30 years, 15.4%; 31-40 years, 14.7%; 41-50 years, 17.0%; 51-60 years, 22.4%; >60 years, 31.0%. Among HPV-positive women, 80.6% had infection with one subtype, 16.4% had dual infection, and 3.1% had three or more subtypes detected. We found 640 cases (16.9%) of infection with high-risk HPV subtypes and 139 cases (5.04%) of infection with low-risk HPV subtypes. The most common high-risk subtypes were HPV 52, 53, 58, and 16; the most common low-risk subtypes were HPV 81, 70, and 42.</p><p><strong>Conclusion: </strong>We detected ≥1 HPV subtype among most women in our study. The prevalence of HPV was lowest in younger women and highest in women age >60 years. Tailored strategies for older women are needed to prevent HPV infection and cervical cancer.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 11","pages":"3000605241291754"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11549702/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142621889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association between admission hyperglycaemia with in-hospital mortality rate in patients with hypertension and acute aortic dissection. 高血压和急性主动脉夹层患者入院时的高血糖与院内死亡率之间的关系。
IF 1.4 4区 医学
Journal of International Medical Research Pub Date : 2024-11-01 DOI: 10.1177/03000605241291742
Saimire Mutailifu, Qing Zhu, Xintian Cai, Mulalibieke Heizhati, Shasha Liu, Yujie Dang, Ting Wu, Jing Hong, Yue Lin, Nanfang Li
{"title":"Association between admission hyperglycaemia with in-hospital mortality rate in patients with hypertension and acute aortic dissection.","authors":"Saimire Mutailifu, Qing Zhu, Xintian Cai, Mulalibieke Heizhati, Shasha Liu, Yujie Dang, Ting Wu, Jing Hong, Yue Lin, Nanfang Li","doi":"10.1177/03000605241291742","DOIUrl":"10.1177/03000605241291742","url":null,"abstract":"<p><strong>Objective: </strong>Admission hyperglycaemia is recognized as a contributor to poor outcomes in patients with cardiovascular and cerebrovascular diseases. This study aimed to evaluate the association between admission hyperglycaemia and in-hospital mortality in patients with hypertension and acute aortic dissection (AAD).</p><p><strong>Methods: </strong>Patients diagnosed with hypertension and AAD between 1 January 2010 and 1 March 2023 were enrolled into this retrospective observational study, and divided into two groups based on admission blood glucose levels (BGA): normoglycemia (BGA < 7.8 mmol/L) and hyperglycaemia (BGA ≥ 7.8 mmol/L). The outcome was all-cause in-hospital mortality, which was analysed using logistic regression to calculate odds ratios (ORs) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>In total, 1239 patients were included (comprising 954 [77%] male patients; mean age, 53.0 years; and median BGA, 6.1 mmol/L). Logistic regression analysis showed that in-hospital mortality was 2.53 times greater for patients with hyperglycaemia versus the normoglycaemia group (95% CI 1.68, 3.80). This significant association persisted after adjustments for potential confounders (adjusted OR 2.45 [95% CI 1.58, 3.85]). Restricted cubic spline analysis revealed that the relationship between BGA and mortality reached statistical significance at BGA > 6.1 mmol/L. Stratified analysis and sensitivity analysis confirmed the robustness of this relationship.</p><p><strong>Conclusion: </strong>Admission hyperglycaemia correlated with an elevated risk of in-hospital mortality in patients with hypertension and AAD, particularly BGA > 6.1 mmol/L, indicating that BGA level may be useful in identifying patients who are at an elevated risk of all-cause mortality.</p>","PeriodicalId":16129,"journal":{"name":"Journal of International Medical Research","volume":"52 11","pages":"3000605241291742"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11585923/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142695160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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