Journal of dentistry最新文献

{"title":"Influence of resin type and new-generation post-processing cleaning solutions on the fabrication trueness and adaptation of additively manufactured denture bases.","authors":"Gülce Çakmak, Lindsay Thérèse Marguerite Duay, Ayyüce Nur Tezcan, Katherine Hidalgo, Pedro Molinero-Mourelle, Burak Yilmaz, Mustafa Borga Dönmez, Martin Schimmel","doi":"10.1016/j.jdent.2026.107057","DOIUrl":"10.1016/j.jdent.2026.107057","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the fabrication trueness and adaptation of additively manufactured denture bases made from different resins and postprocessed with different cleaning solutions.</p><p><strong>Methods: </strong>An edentulous maxillary model was scanned to design a reference denture base file. This reference file was used to fabricate 96 denture bases from three resins (DB, DentaBASE; DT, Denturetec; FD, FREEPRINT Denture) that were cleaned with four solutions (MES, Weiton-3D Resin Cleaner; WBS, Print Cleaning Concentrate; BDS, Cleaning Fluid Bio; isopropyl alcohol [IPA]) (n = 8). All bases were scanned for digital deviation (external, intaglio, and overall root mean square) and adaptation (triple scan, average gap) analyses. Data were analyzed with two-way analysis of variance and Bonferroni-corrected post hoc tests (α = 0.05).</p><p><strong>Results: </strong>FD bases had the lowest and DT bases had the highest intaglio and overall deviations across tested solutions (P ≤ 0.017). DT bases also had the highest external deviations within WBS, BDS, and IPA (P < 0.001). IPA led to higher external and overall deviations than MES for DT bases (P = 0.001). DT bases exhibited the highest gaps, whereas BDS cleaning increased their gaps compared with MES and IPA cleaning (P ≤ 0.044).</p><p><strong>Conclusions: </strong>FD bases mostly had the highest and DT bases mostly had the lowest trueness. Tested cleaning solutions' effect on fabrication trueness was minimal and potentially clinically negligible. DT bases showed the poorest adaptation, irrespective of the solution.</p><p><strong>Clinical significance: </strong>Maxillary FD denture bases may require less chairside adjustments than DT and DB bases, and DB bases might be more prone to retention issues while using tested cleaning solutions. Alcohol-free MES and WBS may be preferred over IPA to clean denture bases in tested resins without compromising their trueness and adaptation.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"107057"},"PeriodicalIF":5.8,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149030682","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"STL triangle count and trueness in prepared tooth regions: Effects of scanner system and scanning mode across intraoral, laboratory, and industrial scanners.","authors":"Hale Arikan Kalayci, Simge Alici, Gülce Çakmak, Hüsniye Yildirim, Mustafa Baris Guncu","doi":"10.1016/j.jdent.2026.107063","DOIUrl":"10.1016/j.jdent.2026.107063","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effects of different scanning modes of intraoral scanners (scan-only versus restoration type selected) on STL triangle counts and to assess the influence of STL triangle counts on trueness across different scanner systems.</p><p><strong>Methods: </strong>A typodont model with 3 prepared teeth was scanned with 15 scanners (11 intraoral, 2 laboratory, and 2 industrial). Intraoral scanners were used in scan-only and restoration type selected modes (n = 10 each); the other scanners were used in a standard workflow (n = 10). Triangle counts were measured in MeshLab within 3 predefined prepared tooth regions. Trueness of intraoral and laboratory datasets was assessed against an ATOS reference scan with best-fit superimposition and root mean square (RMS) deviations. Triangle counts were analyzed with linear mixed-effects models, and RMS deviations with Friedman, post hoc pairwise, and Wilcoxon signed-rank tests (p<.05).</p><p><strong>Results: </strong>STL triangle counts and trueness differed significantly among scanners (p<.001). Triangle counts showed a significant scanner-by-mode interaction, with marked increases for Trios 3 and Trios 5 in restoration type selected mode (p<.001). Among intraoral scanners, the lowest mean RMS values were observed for iTero Lumina in scan-only mode (24 ± 8 µm) and for iTero Lumina and Trios 6 in restoration type selected mode (24 ± 5 µm and 24 ± 9 µm, respectively).</p><p><strong>Conclusions: </strong>Scanner system and scanning mode affected STL triangle count, whereas trueness was influenced primarily by scanner system. Because restoration type selected mode improved trueness only in selected scanners, STL triangle count should be regarded as a complementary descriptor of mesh representation rather than a direct indicator of trueness.</p><p><strong>Clinical significance: </strong>Scanning mode may influence not only STL triangle counts but also trueness; however, this effect appears to be scanner-dependent rather than universally applicable. Therefore, clinicians should be aware that the potential benefit of the restoration type selection mode over the scan-only mode may vary depending on the intraoral scanner system used.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"107063"},"PeriodicalIF":5.8,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149030470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Artificial intelligence for detection of periodontitis on radiographic images: a systematic review and diagnostic test accuracy meta-analysis.","authors":"Xinyue Zhang, Zhixiang Liu, Yan Zhang, Xiaoli An","doi":"10.1016/j.jdent.2026.107054","DOIUrl":"https://doi.org/10.1016/j.jdent.2026.107054","url":null,"abstract":"<p><strong>Objectives: </strong>To determine the diagnostic accuracy of artificial intelligence (AI) models for the periodontitis on radiographic images, and to investigate the factors influencing diagnostic performance.</p><p><strong>Methods: </strong>PubMed, Web of Science, and Cochrane Library were searched until April 2026. A bivariate random-effects model was used to synthesise sensitivity and specificity, and meta-regression explored heterogeneity.</p><p><strong>Results: </strong>Fourteen studies comprising 50,080 radiographic images were included. Seven studies performed diagnosis at the patient level and seven at the tooth or image level. At the patient level, the pooled sensitivity was 0.93 (95%CI, 0.86-0.97), pooled specificity was 0.88 (0.77-0.94), and the area under each curve (AUC) of summary receiver operating characteristic curves (SROC) was 0.96 (0.94-0.97). At the tooth level, pooled sensitivity was 0.90 (0.83-0.94), pooled specificity was 0.94 (95%CI, 0.91-0.96), and the AUC of SROC was 0.97 (0.96-0.98). The meta-regression analysis indicates that none of the algorithm architecture, imaging modality, or external validation are sources of heterogeneity.</p><p><strong>Conclusions: </strong>AI models demonstrate excellent diagnostic accuracy for periodontitis detection. Well-designed prospective studies with robust clinical reference standards, external validation, and transparent reporting are urgently required before these tools can be responsibly integrated into routine dental care. The current evidence base underrepresents low- and middle-income countries, where the burden of periodontitis is greatest and AI-assisted screening could offer the greatest public health benefit.</p><p><strong>Clinical significance: </strong>AI-assisted radiographic screening may particularly benefit general dental practitioners and non-specialist clinicians in primary care or resource-limited settings, where access to periodontists is scarce and diagnostic variability is greatest. By flagging suspected moderate-to-severe periodontitis at the chairside within seconds, such tools could accelerate referral and triage decisions, enabling earlier definitive examination and treatment planning by specialists, while reducing the number of patients with advanced disease who are overlooked during routine dental visits.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"107054"},"PeriodicalIF":5.8,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148990109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Patient, Tooth, and Dentist Characteristics Associated with Multi-Visit Nonsurgical Root Canal Treatment: Findings from the National Dental Practice-Based Research Network\" [Journal of Dentistry 175 (2026) 106949].","authors":"Rahma Mungia, Ellen Funkhouser, Alan S Law, Donald R Nixdorf, Stanley H Asensio Ll, Grace T Chu, Gregg H Gilbert","doi":"10.1016/j.jdent.2026.106995","DOIUrl":"https://doi.org/10.1016/j.jdent.2026.106995","url":null,"abstract":"","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"106995"},"PeriodicalIF":5.8,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148891806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-term outcomes of ceramic crowns in adolescents and young adults with amelogenesis imperfecta: final follow-up of a randomized split-mouth controlled clinical trial","authors":"Gunilla Pousette Lundgren ,&nbsp;Gun-Inger Morling Vestlund ,&nbsp;Göran Dahllöf","doi":"10.1016/j.jdent.2026.106794","DOIUrl":"10.1016/j.jdent.2026.106794","url":null,"abstract":"<div><h3>Objectives</h3><div>Amelogenesis imperfecta (AI) causes functional, esthetic, and psychosocial problems. Although early prosthetic treatment has shown favorable medium-term outcomes, evidence on long-term performance remains limited. This study assessed the ≥10-year clinical performance of Procera zirconia and IPS e.max Press crowns placed in adolescents and young adults with AI.</div></div><div><h3>Methods</h3><div>This study presents the final long-term follow-up of a previously published randomized, split-mouth, controlled clinical trial with patient blinding. In a single-center, double-blind design, 27 adolescents and young adults (aged 11–22 years) with AI received 227 ceramic crowns (119 Procera; 108 IPS e.max Press). Crowns were followed for a mean of 13.4±1.0years (range 11.0–15.3). Outcomes assessed included crown survival, restoration quality according to California Dental Association (CDA) criteria, tooth sensitivity measured on a visual analog scale (VAS), gingival health, and adverse events. Data were analyzed using Kaplan–Meier survival analysis, log-rank tests, chi-square tests, and nonparametric tests.</div></div><div><h3>Results</h3><div>After 13.4years, overall crown survival was 97.8%, with no significant differences by crown material (p=0.110) or AI subtype (p=0.974). Among surviving crowns, 97.0% were rated CDA excellent or acceptable, and 76.1% exhibited excellent marginal integrity. Mean VAS sensitivity decreased from 4.6 before treatment to 0.9 at long-term follow-up (p&lt;0.001), and gingival bleeding was lower than at baseline. Endodontic complications occurred in 3.1% of teeth, primarily associated with prior dental trauma.</div></div><div><h3>Conclusions</h3><div>Ceramic crowns placed in adolescents and young adults with AI demonstrate excellent long- term survival, high clinical quality, and sustained symptom reduction.</div></div><div><h3>Clinical Significance</h3><div>Definitive ceramic crown therapy provides durable, long-term rehabilitation in young individuals with amelogenesis imperfecta.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"173 ","pages":"Article 106794"},"PeriodicalIF":5.5,"publicationDate":"2026-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148054007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation of deep margin elevation in CAD/CAM indirect restorations: A 24-month follow-up study","authors":"Onur Adson,&nbsp;Taha Yasin Sarikaya,&nbsp;Sukran Bolay","doi":"10.1016/j.jdent.2026.106522","DOIUrl":"10.1016/j.jdent.2026.106522","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the two-year clinical performance and survival rate of CAD/CAM-fabricated endocrowns with and without deep margin elevation (DME) in endodontically treated posterior teeth.</div></div><div><h3>Materials and Methods</h3><div>This prospective clinical study included 88 patients (100 teeth) treated at Hacettepe University. Patients were divided into two groups: supragingival margins (SGM, <em>n</em> = 50) and subgingival margins restored using DME (SubGM, <em>n</em> = 50). All teeth had previously completed standardized endodontic treatment performed according to routine clinical protocols. Endodontic procedures were not part of the study protocol. In SubGM cases, the cervical margin was elevated using a highly filled flowable composite (G-ænial Universal Injectable, GC) prior to digital impression and adhesive luting with hybrid ceramic restorations (Cerasmart 270, GC). Clinical outcomes, including marginal integrity, marginal discoloration, and gingival inflammation, were evaluated using modified USPHS criteria at baseline, 6, 12, and 24 months. Survival analysis was performed using the Kaplan-Meier method.</div></div><div><h3>Results</h3><div>The overall 24-month survival rate was 97%. The SGM and SubGM groups showed survival rates of 98% and 96%, respectively, with no statistically significant difference (<em>p</em> &gt; 0.05). Modified USPHS criteria revealed minimal degradation across parameters. No secondary caries were detected. Slightly lower Alpha scores in gingival health and patient satisfaction were observed in the SubGM group but were not statistically significant.</div></div><div><h3>Conclusion</h3><div>DME is a clinically viable technique for restoring deep subgingival margins in endodontically treated molars. Provided proper isolation and adhesion protocols are followed, its short-term performance is comparable to restorations with supragingival margins.</div></div><div><h3>Clinical Significance</h3><div>Deep margin elevation in CAD/CAM indirect restorations may allow clinicians to manage subgingival margins more conservatively, potentially improving restoration longevity and facilitating adhesive procedures without surgical crown lengthening.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106522"},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146125318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the accuracy of Robotic arm and Dynamic Navigation in the placement of mandibular dental implants: An in-vitro study","authors":"Bander N. Al-Meshary ,&nbsp;Mohammed Y. Al-Jarsha ,&nbsp;Kurt B Naudi ,&nbsp;Ashraf Ayoub","doi":"10.1016/j.jdent.2026.106527","DOIUrl":"10.1016/j.jdent.2026.106527","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the spatial accuracy between Robotic Computer-Assisted implant Surgery (R-CAIS) and Dynamic Computer-Assisted Implant Surgery (D-CAIS) for placement of dental implants.</div></div><div><h3>Methods</h3><div>The study was carried out on twelve polyurethane mandibular models which were randomly divided into two groups (n = 6): D-CAIS (group 1) and R-CAIS (group 2). In group 1 the placement of two mandibular implants was carried out manually guided by dynamic navigation. In group 2, the placement of the two mandibular implants was achieved using a robotic arm. The postoperative Cone Beam Computed Tomography (CBCT) scans were superimposed on the predication planning to calculate the errors of the placement of the implants at entry point and at the apex as well as any angulation deviation. The statistical significance of the placement errors was assessed using Student <em>t</em>-tests and Mann–Whitney U tests (<em>p</em> &lt; 0.05) for parametric and non-parametric measurements, respectively.</div></div><div><h3>Results</h3><div>D-CAIS group cases showed significantly lower entry and apex deviations (0.99 ± 0.33 mm; 0.77 ± 0.34 mm) compared to the R-CAIS group (1.82 ± 0.50 mm; 1.30 ± 0.51 mm). Angular deviation was comparable between the two groups (3.97 ± 2.40° vs 4.33 ± 1.83°; <em>p</em> = 0.51). The standard deviations of the linear placement errors (entry and apex) were smaller in the D-CAIS group, whereas the standard deviation of the angular deviation was smaller in the R-CAIS group. Although the angular deviation differed slightly between the two approaches, the results showed no statistically significant difference. The measured implant placement errors of the two approaches were clinically acceptable (&lt; 2 mm; <strong>&lt;</strong> 5°). The measured errors are likely to be secondary to the registration process which was more complex with the application of the robotic arm for the placement of the implants.</div></div><div><h3>Conclusion</h3><div>D-CAIS demonstrated higher accuracy in mandibular implant placement, particularly in terms of linear deviations, while R-CAIS showed greater consistency in angular measurements despite no significant difference between groups. Overall, the observed deviations were small and are of limited clinical significance. These findings reflect system-level performance in a controlled laboratory setting, further clinical studies are required to validate these results.</div></div><div><h3>Clinical significance</h3><div>The study investigated the challenges and opportunities of the clinical application of dynamic navigation and robotic arm for the placement of dental implants. It informs the reader with the related technical details and the digital workflow for each of these two innovative techniques.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106527"},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146093287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of composition, finishing, and salivary pH on physicomechanical and biological properties of additively manufactured resin-ceramic composites: An in vitro study","authors":"Hyun-Tae Kim ,&nbsp;Ye-Hyeon Jo ,&nbsp;Eunbyeol Jee ,&nbsp;Hyung-In Yoon","doi":"10.1016/j.jdent.2026.106547","DOIUrl":"10.1016/j.jdent.2026.106547","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the effects of composition and finishing on the physicomechanical and biological properties of additively manufactured resin-ceramic composites (AM RCs) for definitive restorations under simulated oral environments with different pH levels.</div></div><div><h3>Methods</h3><div>Disk- and bar-shaped specimens were fabricated with 4 AM RCs (Crowntec [CT], Freeprint Crown [FP], VarseoSmile TriniQ [TQ], and VarseoSmile Crown plus [CP]). The specimens underwent either polishing or glazing and were immersed in artificial saliva at neutral and acidic pH levels (37 °C, 7 days). Each saliva-conditioned specimen was evaluated for microhardness (HV), flexural strength (FS), protein adsorption (OD), water sorption (WS), and bacterial adhesion (BA). Cell morphology and migration were evaluated. A 3-way aligned rank transform analysis of variance was performed for HV, FS, OD, WS, and BA, followed by Bonferroni-adjusted Mann–Whitney U tests (α=0.05).</div></div><div><h3>Results</h3><div>CT showed the highest HV (<em>P</em> &lt; 0.001). CT had the highest FS, whereas CP had the lowest (<em>P</em> &lt; 0.05). Glazed AM RCs showed lower OD than polished AM RCs in acidic saliva (<em>P</em> &lt; 0.001). For WS, FP was the highest in neutral saliva, while TQ was the highest in acidic saliva (<em>P</em> &lt; 0.05). BA was significantly affected by salivary pH (<em>P</em> &lt; 0.001).</div></div><div><h3>Conclusion</h3><div>CT showed superior physicomechanical properties. In acidic saliva, all AM RCs showed lower OD after glazing, whereas BA increased regardless of composition or finishing.</div></div><div><h3>Clinical significances</h3><div>Material composition affects the physicomechanical behavior of AM RCs, while salivary pH influences their biological responses. Under acidic salivary conditions, surface glazing may be beneficial, although it does not effectively reduce bacterial adhesion.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106547"},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146132071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antibacterial and demineralisation-inhibiting properties of silver complex fluoride on dentine caries: an in vitro study","authors":"Grace Y Xu ,&nbsp;Iris X Yin ,&nbsp;Irene S Zhao ,&nbsp;Christie YK Lung ,&nbsp;Edward CM Lo ,&nbsp;Chun Hung Chu","doi":"10.1016/j.jdent.2026.106528","DOIUrl":"10.1016/j.jdent.2026.106528","url":null,"abstract":"<div><h3>Objective</h3><div>The objective of this study was to investigate the antibacterial and demineralisation-inhibiting effects of a non-discolouring silver complex fluoride (SCF) on artificial dentine caries.</div></div><div><h3>Methods</h3><div>Dentine blocks with artificial carious lesions were treated with SCF, silver diamine fluoride (SDF, as positive control), and water (as negative control). Then the blocks underwent <em>Streptococcus mutans</em> biofilm and pH–cycling for 7 days. The morphology, viability and growth kinetics of the biofilm were evaluated by scanning electron microscopy (SEM), confocal laser scanning microscopy (CLSM) and colony-forming unit (CFU) counting, respectively. The dentine surface morphology, lesion depths and mineral loss, chemical structure and crystal characteristics were determined using SEM, micro-computed tomography, Fourier transform infrared (FTIR), and X-ray diffraction (XRD), respectively. One-way analysis of variance with the Bonferroni post hoc test was performed to assess and compare the data.</div></div><div><h3>Results</h3><div>SEM revealed confluent bacterial growth covering the surface of dentine treated with water but not SCF and SDF. CLSM showed that the dead-to-live ratios of biofilms treated with SCF, SDF, and water were 0.77 ± 0.16, 0.88 ± 0.40, and 0.44 ± 0.03, respectively (<em>p</em> &lt; 0.001, SCF, SDF&gt;Water). The Log CFU values of the biofilm treated with SCF, SDF and water were 6.7 ± 0.1, 6.6 ± 0.2 and 7.8 ± 0.1 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). SEM images showed Group SCF had less exposed dentine collagen fibers than Group Water. Micro-computed tomography showed the lesion-depth (μm) of dentine treated with SCF, SDF and water were 40±5, 35±8 and 180±20 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). The mineral loss (gHApcm⁻³) of dentine treated with SCF, SDF and water were 0.24±0.05, 0.20±0.03 and 0.45±0.03 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). FTIR showed the amide I-to-hydrogen phosphate ratios of dentine treated with SCF, SDF and water were 0.25±0.03, 0.22±0.03, and 0.43±0.05 (<em>p</em> &lt; 0.001, SCF, SDF&lt;Water). XRD revealed that the hydroxyapatite in SDF and SCF groups was better crystallised than that of water Group.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that SCF inhibited the growth of <em>S. mutans</em> biofilm and reduced the demineralisation of artificial dentine caries.</div></div><div><h3>Clinical significance</h3><div>If SCF is successfully translated into clinical application, it may be a novel anti-caries agent for clinicians to arrest dentine caries</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106528"},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146097038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the 5-year clinical efficacy of cross-arch fixed dental prostheses as periodontal splints on periodontal tissue stability","authors":"Weijie Wu ,&nbsp;Jun Chen ,&nbsp;Yan Liu ,&nbsp;Ganggang Qi ,&nbsp;Chuchu Xu ,&nbsp;Xiaoyu Chen ,&nbsp;Hongye Lu ,&nbsp;Fuming He","doi":"10.1016/j.jdent.2026.106529","DOIUrl":"10.1016/j.jdent.2026.106529","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the clinical efficacy of the cross-arch fixed dental prostheses as periodontal splints and to identify the key factors influencing its treatment outcomes.</div></div><div><h3>Materials and Methods</h3><div>Thirty-seven patients with 51 tooth-supported cross-arch prostheses (mean follow-up: 63 months; mean bridge length: 10.24 units) were retrospectively analyzed. Survival rates, complications, alveolar bone level (ABL), probing pocket depth (PPD), bleeding on probing (BoP), plaque index (PI), prosthesis characteristics, and patient satisfaction were documented at baseline (T0), 1 year (T1), 3 years (T2) and 5 years (T3) after loading. Cumulative survival rates (CSRs) were calculated using Kaplan-Meier curves. Risk factors for changes in PPD (ΔPPD) and alveolar bone level (ΔABL) were screened by univariate analyses and assessed using multivariable generalized linear and logistic regression models.</div></div><div><h3>Results</h3><div>Five-year prosthesis survival was 95.16% (100% at 1- and 3-year). PPD decreased significantly from T0 (3.84 ± 0.81 mm) to T1 (3.26 ± 0.92 mm) and T2 (3.33 ± 0.84 mm; <em>p</em> &lt; 0.05), while ABL remained clinically stable, and BoP and PI were maintained at low levels throughout the study period. Quadrilateral abutment configuration was significantly associated with reduced bone loss (<em>β</em> = -0.551, <em>p</em> = 0.002) and reduced ΔPPD (<em>β</em> = -0.704, <em>p</em> &lt; 0.001). Bilateral terminal abutment prostheses (<em>β =</em> -0.389<em>, p</em> <em>=</em> 0.013) also showed a protective effect on ΔPPD. Patient satisfaction remained high (<em>p</em> &gt; 0.05).</div></div><div><h3>Conclusion</h3><div>Cross-arch fixed prostheses provided predictable periodontal stabilization with high survival rates. Periodontal maintenance and prosthetic design are key determinants of outcomes.</div></div><div><h3>Clinical significance</h3><div>Tooth-supported cross-arch prostheses achieved long-term survival and maintained periodontal parameters in Stage III/IV periodontitis, supporting their use as long-span splints when properly planned and maintained. Abutment distribution and strict supportive periodontal care were key determinants, guiding prosthetic design and follow-up.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"167 ","pages":"Article 106529"},"PeriodicalIF":5.5,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146113366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}