Journal of dentistry最新文献

{"title":"Reduction of the erosive potential of a soft drink with polymers and calcium","authors":"Cláudia Allegrini Kairalla ,&nbsp;Milena Rodrigues Muniz ,&nbsp;Letícia Oba Sakae ,&nbsp;Fernando Neves Nogueira ,&nbsp;Idalina Vieira Aoki ,&nbsp;Juliano Pelim Pessan ,&nbsp;Alessandra Bühler Borges ,&nbsp;Taís Scaramucci","doi":"10.1016/j.jdent.2025.105935","DOIUrl":"10.1016/j.jdent.2025.105935","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the erosive potential of a soft drink modified with film-forming polymers and calcium on bovine enamel and dentin.</div></div><div><h3>Methods</h3><div>Sprite Zero Sugar was modified with linear sodium polyphosphate (LPP–10 g/L) and sodium trimetaphosphate (TMP-10 g/L), individually or combined with calcium lactate pentahydrate (CLP–4.35 g/L). Enamel and dentin specimens were randomly assigned into six groups (<em>n</em> = 10/substrate): 1. <em>C</em>− (negative control–no modification); 2. LPP; 3. TMP; 4. LPP+CLP; 5. TMP+CLP; 6. <em>C</em>+ (positive control–CLP). The specimens underwent an erosion-remineralization cycling. Surface loss (SL, in μm) was measured with an optical profilometer. Color and viscosity of the drinks were analyzed. Data were statistically analyzed (α=0.05).</div></div><div><h3>Results</h3><div>For enamel and dentin, LPP significantly reduced the erosive effect of the drink compared to C- (<em>p</em> &lt; 0.001 for both), with reductions of approximately 53 % and 41 %, respectively. TMP showed no significant difference from <em>C</em>− for both substrates. <em>C</em>+ reduced SL by 87 % in enamel and 38 % in dentin when compared to <em>C</em>− (<em>p</em> &lt; 0.001). When CLP was combined with the polymers, in enamel, a 97 % reduction in SL for LPP+CLP and TMP+CLP was observed. In dentin, reductions of 56 % and 48 % were observed for LPP+CLP and TMP+CLP. No significant differences were observed between the groups and the C- regarding color and viscosity (<em>p</em> &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>All solutions containing calcium lactate (CLP) were effective in reducing the erosive potential of the original soft drink. The combinations of CLP with LPP or TMP significantly enhanced protection, especially for dentin. Notably, LPP alone was effective in minimizing erosion of both enamel and dentin.</div></div><div><h3>Clinical relevance</h3><div>Reducing the erosion potential of soft drinks may benefit non-collaborative individuals with high risk for erosive tooth wear.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105935"},"PeriodicalIF":4.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Accuracy of Active and Passive Dynamic Navigation Systems in Dental Implant Surgery: A Retrospective Study.","authors":"Chunxiao Jin, Zhiyi Zhu, Yaping Guo, Shikai Zhao, Cui Huang","doi":"10.1016/j.jdent.2025.105938","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105938","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the accuracy of implant placement using active dynamic navigation systems (ADNS) and passive dynamic navigation systems (PDNS) in clinical environment.</p><p><strong>Methods: </strong>This retrospective study (October 2021 to December 2024) evaluated cone-beam computed tomography (CBCT) data from 58 partially edentulous patients who received 70 implants, with 35 implants placed using an ADNS and 35 using a PDNS. Preoperative and postoperative CBCT scans were automatically superimposed using specialized software to calculate deviations between planned and actual implant positions. Angular, platform, and apex deviations were assessed in both two-dimensional (2D) and three-dimensional (3D) measurements.</p><p><strong>Results: </strong>The 3D deviations for the ADNS versus PDNS were 1.06 ± 0.52 mm versus 1.37 ± 0.62 mm at the implant platform (p< 0.05); 1.12 ± 0.53 mm versus 1.37 ± 0.53 mm (p > 0.05) at the implant apex; 2.60 ± 1.28° versus 3.58 ± 0.98° in angular deviation (p < 0.05). In the 2D analysis, the ADNS group showed significantly lower buccolingual and mesiodistal deviations at the implant platform and lower mesiodistal deviations at the apex compared with the PDNS group. No significant differences were observed in implant deviation distributions across the lingual, buccal, apical, coronal, mesial, or distal directions.</p><p><strong>Conclusions: </strong>Both ADNS and PDNS exhibited accuracy within clinically acceptable thresholds across most scenarios. However, the ADNS demonstrated slightly superior implant placement accuracy in the right areas.</p><p><strong>Clinical significance: </strong>ADNS enables more accurate implant placement than PDNS, significantly reducing deviations in complex regions, such as the right posterior and anterior areas. This accuracy lowers risks of anatomical compromise and prosthetic complications, supporting the clinical preference for ADNS in challenging cases.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105938"},"PeriodicalIF":4.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and characterisation of a novel antimicrobial peptide GA-C16G2 targeting Streptococcus mutans","authors":"Yipeng Fu ,&nbsp;Richard D. Cannon ,&nbsp;Kai Chun Li ,&nbsp;Manikandan Ekambaram ,&nbsp;Paul R. Cooper ,&nbsp;May L. Mei","doi":"10.1016/j.jdent.2025.105927","DOIUrl":"10.1016/j.jdent.2025.105927","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to develop a <em>Streptococcus mutans</em> (<em>S. mutans</em>)-targeted peptide for caries management and evaluate its antibacterial efficacy.</div></div><div><h3>Methods</h3><div>A novel peptide, GA-C16G2, was synthesised by attaching gallic acid (GA) onto an <em>S. mutans</em>-targeted antimicrobial peptide, C16G2. Peptide purity and stability were measured using high-performance liquid chromatography (HPLC). The secondary structure of GA-C16G2 was assessed using circular dichroism (CD) spectroscopy, and cytotoxicity was evaluated with the PrestoBlue assay. Antimicrobial activity against oral bacterial species was determined using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) assays. Time-kill and biofilm inhibition assays further characterised the peptide’s activity. Bacterial morphology and biofilm structure were analysed by transmission electron microscopy (TEM) and scanning electron microscopy (SEM).</div></div><div><h3>Results</h3><div>GA-C16G2 was synthesised with 95.02 % purity, and its secondary structure closely resembled that of the parent peptide C16G2. GA-C16G2 exhibited good stability in artificial saliva and showed low cytotoxicity towards human gingival fibroblasts. GA-C16G2 demonstrated potent antimicrobial activity against <em>S. mutans</em> (MIC: 3.1 μM, MBC: 20.8 μM) while showing weaker effects against commensal bacterial species. A time-kill assay confirmed the rapid bactericidal activity of GA-C16G2, reducing <em>S. mutans</em> viability by 97.22 % within one minute. GA-C16G2 also inhibited <em>S. mutans</em> biofilm formation. TEM and SEM images confirmed bacterial and biofilm disruption.</div></div><div><h3>Conclusion</h3><div>This study demonstrates the successful development of a biocompatible and stable peptide, GA-C16G2, with rapid and potent selective <em>in vitro</em> antimicrobial activity against <em>S. mutans</em>.</div></div><div><h3>Clinical significance</h3><div>GA-C16G2 offers a novel therapeutic approach for targeted prevention and treatment of dental caries.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105927"},"PeriodicalIF":4.8,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In-office Bleaching After a Desensitizing Protocol: a 4.5-Year Follow-up of a Randomized Controlled Trial","authors":"Diego Hortkoff ,&nbsp;Paulo Vitor Farago ,&nbsp;João Carlos Gomes ,&nbsp;Alessandra Reis ,&nbsp;Giovana Mongruel Gomes","doi":"10.1016/j.jdent.2025.105932","DOIUrl":"10.1016/j.jdent.2025.105932","url":null,"abstract":"<div><h3>Objectives</h3><div>This clinical trial aims to evaluate the bleaching efficacy and longevity of in-office bleaching after 4.5 years with or without ibuprofen/arginine desensitization.</div></div><div><h3>Methods</h3><div>Sixty-two patients, canines darker than A2 and in good general and oral health were selected and their hemi-arches randomized to receive an ibuprofen-arginine or placebo desensitizing gels before in-office dental bleaching. Two bleaching sessions (35% hydrogen peroxide gel; 1-week) were performed. Color change was evaluated using the Vita Classical, Vita Bleachedguide (ΔSGU), and Vita EasyShade spectrophotometer (ΔE_ab, ΔE₀₀, WI_D) before dental bleaching, one month and 4.5 years after the bleaching procedure. Data was evaluated by paired t-test (α = 0.05). Long-term dental tooth sensitivity, patient satisfaction and desire for a new bleaching procedure were evaluated.</div></div><div><h3>Results</h3><div>After 4.5 years, no significant difference in color change was found between the desensitizing and placebo sides (p &gt; 0.05). A significant color rebound was observed (mean ΔSGU Classical 2.1 units, per-protocol analysis), though bleaching effects remained clinically relevant. Long-term tooth sensitivity was reported by 25.5% of participants. Patient satisfaction was moderate (mean VAS 6.7 ± 2.6), with 85.1% expressing interest in additional bleaching.</div></div><div><h3>Conclusions</h3><div>In-office dental bleaching showed sustained whitening effects after 4.5 years, despite a mild color rebound.</div></div><div><h3>Clinical relevance</h3><div>In-office bleaching maintains clinically acceptable whitening for over 4 years despite slight color rebound.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105932"},"PeriodicalIF":4.8,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505864","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"UK Implementation of 'Treatment of Stage IV Periodontitis: The EFP S3-Level Clinical Practice Guideline' - Rehabilitation of Severe Periodontitis Patients.","authors":"Moritz Kebschull, Iain Chapple, Francesco D'Aiuto, Nikos Donos, Padhraig S Fleming, Matthew Jerreat, Giles McCracken, Ian Needleman, Luigi Nibali, Nicola West","doi":"10.1016/j.jdent.2025.105847","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105847","url":null,"abstract":"<p><strong>Objectives: </strong>To adapt the supranational European Federation for Periodontology (EFP) S3-Level Clinical Practice Guideline for treatment of very severe periodontitis (stage IV) to a UK healthcare environment, considering views of a broad range of stakeholders, and patients.</p><p><strong>Sources: </strong>This UK version is based on the supranational EFP guideline published in the Journal of Clinical Periodontology. The source guideline was developed using the S3-level methodology, combining assessment of formal evidence from 13 systematic reviews with a moderated consensus process of a representative group of dental discipline stakeholders, accounting for health equality, environmental factors and clinical effectiveness. This guideline encompasses 47 clinical recommendations for the treatment of stage IV periodontitis, based on a step-wise process mapped to the 2018 periodontal and peri-implant diseases and conditions classification and UK classification implementation.</p><p><strong>Methodology: </strong>The UK version was developed from the source guideline using a formal process called the GRADE ADOLOPMENT framework. The adoption allows (unmodified acceptance) adaptation (acceptance with modifications) and the de novo development of clinical recommendations. Using this framework and following the S3-process, the underlying evidence was updated and a representative guideline group of 101 delegates from 19 stakeholder organisations was assembled into three working groups. Following the formal S3-process, all clinical recommendations were formally assessed for their applicability to the UK and adoloped accordingly.</p><p><strong>Results and conclusion: </strong>Using the ADOLOPMENT protocol, a UK version of the EFP S3-level Stage IV clinical practice guideline was developed. This guideline delivers evidence- and consensus-based clinical recommendations of direct relevance to the UK dental community.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105847"},"PeriodicalIF":4.8,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Teaching critical appraisal and research methodology to dental students and practitioners: A scoping review","authors":"Danchen Qin ,&nbsp;Xiaojin Wu ,&nbsp;Fangyu Li ,&nbsp;Xueqian Yu ,&nbsp;Fang Hua","doi":"10.1016/j.jdent.2025.105930","DOIUrl":"10.1016/j.jdent.2025.105930","url":null,"abstract":"<div><h3>Objective</h3><div>Critical appraisal (CA) and research methodology (RM) are essential skills for evidence-based dentistry (EBD). This scoping review aims to summarize the existing evidence and experience regarding the teaching of CA and RM to dental students and practitioners.</div></div><div><h3>Data sources</h3><div>A systematic search was conducted in PubMed, Embase, Web of Science, and ERIC, supplemented with manual and citation searches.</div></div><div><h3>Study selection</h3><div>Two researchers performed article selection and data extraction independently.</div></div><div><h3>Data analysis</h3><div>Data were analysed using frequency tabulation and thematic content analysis.</div></div><div><h3>Results</h3><div>A total of 53 articles were identified and included, among which a majority (39/53, 73.6 %) were research studies, while the rest (14/53, 26.4 %) were narrative articles. Most of the research studies (33/39, 84.6 %) were observational, while only 1 used a randomized controlled design. About three-fifths (31/53, 58.5 %) focused on broad teaching of EBD, incorporating CA or RM as part of teaching content. Professional degree education (DDS, DMD, BDS, etc.) was described most frequently (38/53, 71.7 %), followed by postgraduate/resident education (12/53, 22.6 %), faculty development (6/53, 11.3 %), and continuing education (4/53, 7.5 %). The teaching outcomes of CA or RM were rarely assessed independently, and the majority assessed comprehensive EBD skills in the short term. Only 26.4 % (14/53) mentioned teaching evaluation, primarily about teaching content and based on student feedback.</div></div><div><h3>Conclusions</h3><div>Research on CA or RM education in dentistry is predominantly observational, which typically adopted before-and-after self-comparison designs or uncontrolled designs. There remains a lack of evidence regarding the long-term effects of CA and RM teaching activities and their influence on clinical practice.</div></div><div><h3>Clinical Significance</h3><div>Teaching CA and RM equips dental practitioners with essential skills to implement evidence-based practice and improve the quality of dental care. Our findings indicate that current evidence on CA and RM teaching in dentistry is limited. This review provides insights to inform dental curriculum innovation and continuing education enhancement, ultimately facilitating the advancement of evidence-based dental practice.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105930"},"PeriodicalIF":4.8,"publicationDate":"2025-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144484612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effect of viscoelastic behavior of resin-based dental materials on the resin-dentin shear bond strength","authors":"Ying He ,&nbsp;Cui-Ting Chen ,&nbsp;Lin Li ,&nbsp;Yan-Xia Zhou ,&nbsp;Ke Zhao ,&nbsp;Yan-Dong Mu ,&nbsp;Xiao-Dong Wang","doi":"10.1016/j.jdent.2025.105926","DOIUrl":"10.1016/j.jdent.2025.105926","url":null,"abstract":"<div><h3>Objectives</h3><div>1) To clarify the effect of static or dynamic viscoelastic behavior of dentin and three resin-based dental materials on resin-dentin interfacial shear bond strength. 2) To investigate the influence of resin-based dental materials' viscoelastic behavior on residual stress at resin-dentin interface using finite element analysis (FEA).</div></div><div><h3>Methods</h3><div>Resin-dentin bonded specimens of three resin-based dental materials underwent monotonic compression, static and dynamic bulk compressive creep tests. Then shear bond strength, failure modes, and interface morphology were assessed. Additionally, polymerization shrinkage (<em>s</em>) and Young’s modulus (<em>E</em>) for the materials were determined using buoyancy method and dynamic mechanical analysis (DMA), respectively. Cylindrical specimens underwent static/dynamic creep tests to collect stress-strain data. Finally, FEA was employed to assess the residual stress distribution at resin-dentin interface with/without creep tests.</div></div><div><h3>Results</h3><div>1) Compared to monotonic compression, both static and dynamic creep significantly increased resin-dentin bond strength (<em>p</em> &lt; 0.05), with dynamic creep superior. 2) Monotonic compression primarily caused mixed adhesive and cohesive failures, while bulk compressive creep tests reduced adhesive failure and increased cohesive failure. 3) Monotonic compression caused more hollow dentin tubules and pulled-out resin tags, whereas bulk compressive creep tests revealed resin tags inside tubules and cracks between resin and dentin. 4) FEA indicated stress concentration at margins of the bonded area, with the resin adhesive layer experiencing the highest stress. After bulk compressive creep tests, stress distribution became more uniform, and residual stress decreased by 50 % or more.</div></div><div><h3>Conclusions</h3><div>Bulk compressive creep improves resin-dentin bond strength by facilitating interfacial stress relaxation. The resin-based dental materials' viscoelastic behavior mitigates polymerization shrinkage stress, enabling effective stress relaxation at resin-dentin interface.</div></div><div><h3>Clinical Significance</h3><div>During direct restoration process, resin-based dental materials with appropriate viscoelastic properties can effectively reduce polymerization shrinkage stress. This, in turn, promotes efficient stress relaxation at the resin-dentin interface and enhances bonding performance.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"160 ","pages":"Article 105926"},"PeriodicalIF":4.8,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dental services use prediction among adults in Southern Brazil: A gender and racial fairness-oriented machine learning approach","authors":"Luiz Alexandre Chisini ,&nbsp;Cínthia Fonseca Araújo ,&nbsp;Felipe Mendes Delpino ,&nbsp;Lílian Munhoz Figueiredo ,&nbsp;Alexandre Dias Porto Chiavegatto Filho ,&nbsp;Helena Silveira Schuch ,&nbsp;Bruno Pereira Nunes ,&nbsp;Flávio Fernando Demarco","doi":"10.1016/j.jdent.2025.105929","DOIUrl":"10.1016/j.jdent.2025.105929","url":null,"abstract":"<div><h3>Objective</h3><div>To develop machine learning models to predict the use of dental services among adults aged 18 and older.</div></div><div><h3>Methods</h3><div>This is a prospective cohort study that uses data from the survey “EAI Pelotas?”. The sample consisted of individuals who participated in both the baseline and follow-up, totaling 3461 people. Predictors were collected as baseline and comprised 47 sociodemographic, behavioral, oral and general health characteristics. The outcome was dental service use in the last year assessed during the one-year follow-up. Data was divided into training (80 %) and test (20 %) sets. Five machine learning models were tested. Hyperparameter tuning was optimized through 10-fold cross-validation, utilizing 30 iterations. Model performance was assessed based on the area under the Receiver Operating Characteristic (ROC) curve (AUC), accuracy, recall, precision, and F1-score.</div></div><div><h3>Results</h3><div>The prevalence of dental service use in the follow-up was 47.2 % (95 % CI, 45.5 – 48.9). All models in the test set demonstrated an AUC-ROC between 0.76 and 0.77. The CatBoost Classifier model exhibited the highest performance in the test dataset among the models concerning the AUC metric (AUC = 0.77, CI95 %,[0.73–0.80]), displaying an accuracy = 0.69, recall = 0.69, precision = 0.68, and F1-score = 0.69. Fairness estimations for the best model indicated consistent performance across gender categories. However, disparities were observed among racial groups, AUC = 0.57 for individuals who self-reported mixed (“<em>pardos”</em>) skin color. The explainability analysis shows that the most important features were the last dental visit at baseline and education level.</div></div><div><h3>Conclusion</h3><div>Despite our findings suggesting a sufficient prediction of overall dental services’ use, performance varied across racial groups.</div></div><div><h3>Clinical significance</h3><div>Our findings highlight the potential of machine learning models to predict dental service use with good overall accuracy. However, the significantly lower performance for mixed-race individuals raises concerns about fairness and equity. Therefore, despite promising results, the model requires further refinement before it can be applied in real-world public health settings.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105929"},"PeriodicalIF":4.8,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Automated chart filing on bitewings using deep learning: enhancing clinical diagnosis in a multi-center study","authors":"Lingyun Cao ,&nbsp;Niels van Nistelrooij ,&nbsp;Eduardo Trota Chaves ,&nbsp;Stefaan Bergé ,&nbsp;Maximiliano Sergio Cenci ,&nbsp;Tong Xi ,&nbsp;Bas Loomans ,&nbsp;Shankeeth Vinayahalingam","doi":"10.1016/j.jdent.2025.105919","DOIUrl":"10.1016/j.jdent.2025.105919","url":null,"abstract":"<div><h3>Objectives</h3><div>Bitewings are commonly used radiographs for visualizing teeth and various dental conditions. Manual labeling and diagnosis on bitewings for chart filing are time-consuming and prone to observer-dependent variations. This multi-center study proposes a deep learning (DL) approach to automate comprehensive chart filing of bitewings.</div></div><div><h3>Methods</h3><div>A total of 1045 bitewings from Germany and The Netherlands were used for training and validation, and 216 from Slovakia for external testing. Annotations were performed by two dentists, one PhD researcher, and one caries expert. Hierarchical Mask DINO was developed for multi-class hierarchical end-to-end instance segmentation. Unmodified Mask DINO, SparseInst, and Mask R-CNN were used for comparison. Model performance was evaluated using F1-score, sensitivity, specificity, precision, mean average precision (mAP), and area under receiver operating characteristic curve (AUC).</div></div><div><h3>Results</h3><div>Mask DINO models exhibited high effectiveness for tooth segmentation and labeling, achieving precision, sensitivity, and F1-scores above 0.96. Hierarchical Mask DINO outperformed the other models in dental finding classification. F1-scores for implant, crown, pontic, filling, root canal treatment (RCT), caries lesion, and calculus deposit were 0.944, 0.918, 0.952, 0.956, 0.988, 0.749, and 0.758, respectively, with specificities all above 0.95.</div></div><div><h3>Conclusions</h3><div>This study presented a DL-based approach for comprehensive assessment and diagnosis of bitewings, underlining its potential to enhance the efficiency and accuracy of chart filing in dental practice.</div></div><div><h3>Clinical significance</h3><div>The proposed model provided fully automated tooth segmentation and numbering, along with comprehensive segmentation of dental conditions. Dental professionals can benefit from this model for reducing manual workload and enhancing clinical diagnosis.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105919"},"PeriodicalIF":4.8,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Patient-Reported Outcomes of Digitally vs. Conventionally Fabricated Frameworks in Removable Partial Dentures: A Systematic Review and Meta-Analysis.","authors":"Elena Mühlemann-Kazanchian, Margherita Giorgia Liguori, Aspasia Pachiou, Ronald Jung, Franz Josef Strauss","doi":"10.1016/j.jdent.2025.105920","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105920","url":null,"abstract":"<p><strong>Objective: </strong>Digital workflows are increasingly used for fabricating metal frameworks of removable partial dentures (RPDs), offering advantages in clinical efficiency and reproducibility. This systematic review aimed to compare patient-reported outcomes (PROMs) between conventionally and digitally fabricated RPDs.</p><p><strong>Methods: </strong>An electronic and manual search was conducted up to January 1, 2025, to identify clinical trials and cohort studies evaluating PROMs for conventional and digital RPD frameworks. Studies using validated tools, including visual analogue scales (VAS) and oral health-related quality of life (OHRQoL) questionnaires, were included. Two reviewers independently performed study selection, data extraction, and quality assessment. Meta-analyses were conducted using weighted mean differences (WMD) or standardized mean differences (SMD) with 95% confidence intervals (CIs), applying a random-effects model.</p><p><strong>Results: </strong>Out of 942 identified studies, four met the inclusion criteria (59 patients, 118 RPDs), with three eligible for meta-analyses. Digitally fabricated RPDs showed significant improvements in speech (WMD = 1.01; 95% CI: 0.03 to 1.99; p = 0.04), cleanability (WMD = 0.66; 95% CI: 0.00 to 1.31; p = 0.05), and prosthesis stability (WMD = 1.24; 95% CI: 0.01 to 2.46; p = 0.05). No significant differences were found in esthetic perception, overall satisfaction, or OHRQoL.</p><p><strong>Conclusion: </strong>Digital workflows may improve specific aspects of patient comfort, particularly speech, hygiene, and stability, but offer similar outcomes to conventional methods in terms of satisfaction and esthetic perception.</p><p><strong>Clinical significance: </strong>Digitally fabricated RPD frameworks may improve patient comfort by enhancing speech clarity, hygiene maintenance, and prosthesis stability. These benefits can support better long-term outcomes and reduced clinical chair time, suggesting that digital workflows represent a reliable and efficient alternative to conventional fabrication methods.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105920"},"PeriodicalIF":4.8,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144475486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}