Journal of dentistry最新文献

{"title":"Emergence angle and profile at implant-supported crowns with and without cantilever extension: A digital study in molar sites","authors":"Xiaoyu Yu ,&nbsp;Yuan Li ,&nbsp;Yu Xie ,&nbsp;Mengning Bi ,&nbsp;Hairui Li ,&nbsp;Andrea Roccuzzo ,&nbsp;Maurizio S. Tonetti","doi":"10.1016/j.jdent.2025.106135","DOIUrl":"10.1016/j.jdent.2025.106135","url":null,"abstract":"<div><h3>Objectives</h3><div>To compare the emergence angle between cantilever and non-cantilever digital designs for implant-supported crowns at molar sites, offering digital analysis insights for evaluating restoration strategy selection.</div></div><div><h3>Methods</h3><div>One hundred patients missing the first molar underwent intraoral scanning and CBCT imaging. Data were imported into digital platforms for prosthetic-driven planning and virtual design of implants, abutments and crowns. Two designs (cantilever and non-cantilever) were created for each patient. Emergence angles were measured using both 2D and 3D software. Simple and multiple linear regression models were employed to analyze associations between emergence angles and clinically relevant parameters (crown height and edentulous space).</div></div><div><h3>Results</h3><div>The mesio-distal width of first molar edentulous spaces averaged 10.5 ± 0.8 mm (range: 9.0–12.5 mm). For cantilever restorations, 2D angles measured 23.0 ± 4.5° (mesial) and 22.4 ± 4.6° (distal). Non-cantilever restorations exhibited greater angles, with 2D measurements of 29.1 ± 5.6° (mesial) and 30.4 ± 6.3° (distal) (<em>p</em> &lt; 0.001). When categorizing edentulous spaces into three ranges (9.0–9.9 mm, 10.0–10.9 mm, and 11.0–12.5 mm), mesio-distal emergence angles exceeding 30° occurred in 1.6 %, 2.3 %, and 10.0 % of cantilever designs respectively, compared to 25.8 %, 54.6 %, and 58.0 % in non-cantilever designs (<em>p</em> &lt; 0.001). Cantilever designs consistently produced smaller emergence angles across all edentulous space dimensions.</div></div><div><h3>Conclusions</h3><div>Cantilever implant restorations demonstrated smaller emergence angles than non-cantilever designs, suggesting potential advantages for peri‑implant health maintenance. These findings provide geometric evidence that may support cantilever designs for first molar replacements when anatomically feasible, though long-term clinical validation remains needed.</div></div><div><h3>Clinical Significance</h3><div>The proposed digital emergence angle analysis represents a useful diagnostic method to optimize prosthetic design in use of implant-supported crowns with cantilever extension.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106135"},"PeriodicalIF":5.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145186019","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pull-out force and fracture load of fully sintered zirconia hybrid abutment-crowns on Ti-base abutments: Surface treatment effects and material comparison","authors":"Qiucen Wan ,&nbsp;Dong-Hun Lee ,&nbsp;Ryan Jin Young Kim ,&nbsp;In-Sung Luke Yeo ,&nbsp;Jae-Hyun Lee ,&nbsp;Irena Sailer","doi":"10.1016/j.jdent.2025.106134","DOIUrl":"10.1016/j.jdent.2025.106134","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the effect of surface treatment on the pull-out force of implant restorations supported by Ti-bases and milled from fully sintered niobium oxide-containing yttria-stabilized tetragonal zirconia polycrystals ([Y, Nb]-TZP), and to compare their fracture load with that of lithium disilicate (LD) and polymer-infiltrated ceramic network (PICN) restorations.</div></div><div><h3>Methods</h3><div>To evaluate pull-out force, 40 (Y, Nb)-TZP hybrid abutment-crown specimens were divided into four groups based on the surface treatment applied (<em>n</em> = 10): no surface treatment (FSZ-N group), airborne-particle abrasion (APA) (FSZ-A group), a 10-methacryloyloxydecyl dihydrogen phosphate (MDP) primer (FSZ-M group), and both APA and a 10-MDP primer (FSZ-AM group). After cementation and thermocycling, the pull-out forces and failure modes were examined by pull-out testing. To evaluate fracture load, 30 hybrid abutment-crown specimens were milled from (Y, Nb)-TZP (fully sintered zirconia; FSZ group), LD (LD group), and PICN (PICN group) blocks (<em>n</em> = 10). Following cementation and thermocycling, fracture loads and failure modes were recorded.</div></div><div><h3>Results</h3><div>The FSZ-M and FSZ-AM groups demonstrated significantly higher pull-out forces than the FSZ-N group. The FSZ-A group showed the lowest pull-out force. The LD group had a higher fracture load than the PICN group. The fracture load of the FSZ group showed no significant difference compared with the LD or PICN group.</div></div><div><h3>Conclusions</h3><div>Applying a 10-MDP-containing primer enhanced the pull-out force of hybrid abutment-crowns milled from fully sintered (Y, Nb)-TZP, with or without APA. Implant restorations fabricated from this material and supported by Ti-base abutments exhibited a fracture load comparable to that of LD and PICN restorations.</div></div><div><h3>Clinical significance</h3><div>For implant restorations milled from fully sintered zirconia and supported by Ti-base abutments, applying a 10-MDP-containing primer is a key step for improving retention. Furthermore, their fracture load, which is comparable to other restorations milled from established materials, supports their potential for clinical use on Ti-base abutments.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106134"},"PeriodicalIF":5.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of diagnostic performance of mid-palatal and transverse palatine suture maturation assessment according to cone-beam computed tomography resolution","authors":"Leda Kroselj Zevnik ,&nbsp;Jasmina Primozic","doi":"10.1016/j.jdent.2025.106137","DOIUrl":"10.1016/j.jdent.2025.106137","url":null,"abstract":"<div><h3>Objective</h3><div>The aim was to assess the diagnostic performance of the qualitative maturational assessment of the mid-palatal and transverse palatine suture and to verify whether it is influenced by the cone-beam computed tomography (CBCT) image resolution.</div></div><div><h3>Methods</h3><div>A total of 120 (60 medium and 60 high-resolution) CBCT images for the mid-palatal suture (62 males, 58 females, mean age 28.6 ± 18.6) and transverse palatine suture (61 males, 59 females, mean age 29.0 ± 18.7) maturity assessment was selected. Three examiners, who successfully completed training, assessed the maturation of both sutures, separately. Diagnostic performance parameters according to different CBCT resolution and assessment session were calculated.</div></div><div><h3>Results</h3><div>The examiners presented slightly higher intra and inter-examiner agreements when assessing medium-resolution compared to high-resolution CBCT images, for both sutures. Stages B and E (for both sutures) showed the highest agreement with the reference standard, while stages C and D showed the lowest, regardless of resolution and assessment session. However, for transverse palatine suture, the agreement was overall poorer. The diagnostic parameters were generally similar between the different resolutions and assessment sessions. For each mid-palatal suture maturation stage, the diagnostic accuracy values were above 91.6 %, while transverse palatine suture showed lower values, above 91.8 % for stages B and E and 77.7 % for stages C and D.</div></div><div><h3>Conclusion</h3><div>Assessment of both sutures’ maturational stages proves to be accurate and repeatable to a satisfactory level with no significant difference between medium and high-resolution CBCT images. From a clinical standpoint, using medium-resolution CBCT scans is advisable to reduce radiation exposure risks in most cases.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106137"},"PeriodicalIF":5.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145182121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"In vitro study of cold atmospheric plasma-induced proliferation inhibition and morphological changes in head and neck carcinoma cell lines\" [Journal of Dentistry161 (2025) 106007].","authors":"Tatjana Maravic, Giulia Petrucci, Viviana di Giacomo, Claudia Mazzitelli, Tirtha Raj Acharya, Nagendra Kumar Kaushik, Eun Ha Choi, Monica Rapino, Diego D'Urso, Uros Josic, Vito Carlo Alberto Caponio, Massimo Micaroni, Edoardo Mancuso, Lucio Lo Russo, Lorenzo Lo Muzio, Lorenzo Breschi, Vittoria Perrotti","doi":"10.1016/j.jdent.2025.106098","DOIUrl":"10.1016/j.jdent.2025.106098","url":null,"abstract":"","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"106098"},"PeriodicalIF":5.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is medication-related osteonecrosis of the jaw around dental implants associated with the implant design and prosthesis characteristics?","authors":"Jaeyeon Kim ,&nbsp;Jun-Young Kim ,&nbsp;Eun-Jeong Choi ,&nbsp;Hyeon-Gyu Jo ,&nbsp;Hyung Jun Kim ,&nbsp;Wonse Park","doi":"10.1016/j.jdent.2025.106133","DOIUrl":"10.1016/j.jdent.2025.106133","url":null,"abstract":"<div><h3>Purpose</h3><div>This study aimed to identify risk factors associated with medication-related osteonecrosis of the jaw (MRONJ) around dental implants, focusing on implant/prosthesis characteristics and peri-implantitis.</div></div><div><h3>Methods</h3><div>This retrospective study included 355 dental implants obtained from 67 patients, each with at least one implant affected by MRONJ, who visited Yonsei University Dental Hospital between January 2008 and March 2022. The outcome variable was the presence or absence of MRONJ. Predictor variables included implant location, crestal module design, prosthesis type, emergence profile, emergence angle (EA), and peri-implantitis. A generalized estimating equation model was used to adjust for within-patient clustering effects.</div></div><div><h3>Results</h3><div>A total of 355 implants were analyzed, of which 112 implants were affected by MRONJ and 243 were not affected. External-type implants had higher odds of MRONJ than tissue-level implants (OR, 4.07; 95 % CI, 1.23–13.45). The odds of MRONJ were higher in implants with peri-implantitis compared to those without peri-implantitis (OR, 7.43; 95 % CI, 2.74–20.14). In tissue-level implants, MRONJ was significantly associated with a convex profile (39.1 %) than in those with straight or concave profiles (15.8 %). In bone-level implants, MRONJ was significantly higher in prostheses with an EA of &gt;30º on at least one side, compared to those with EA of ≤30º on both sides. In addition, implants placed in the molar region had a significantly wider EA and more frequent convex profiles than those placed in the premolar region.</div></div><div><h3>Conclusions</h3><div>MRONJ affected dental implants may be associated with crestal module design. In addition, implant prosthesis characteristics may influence MRONJ occurrence depending on the implant design, and in patients receiving antiresorptive therapy, implant design should be carefully planned with consideration of the anatomical location to minimize the risk of MRONJ.</div></div><div><h3>Clinical Significance</h3><div>Implant design should be considered when planning implant treatment in patients receiving antiresorptive therapy, especially in anatomically vulnerable areas such as the molar region.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106133"},"PeriodicalIF":5.5,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145176041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Data sharing for responsible artificial intelligence in dentistry: a narrative review of legal frameworks and privacy-preserving techniques.","authors":"Janet Brinz, Negin Eslamiamirabadi, Ali Salamati, Volker Tresp, Falk Schwendicke, Antonin Tichy","doi":"10.1016/j.jdent.2025.106130","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.106130","url":null,"abstract":"<p><strong>Objectives: </strong>Data sharing is essential for ensuring research reproducibility and for developing generalizable artificial intelligence (AI) systems, but it demands robust safeguards for patient privacy. This narrative review aims to guide dental clinicians and researchers in sharing patient data responsibly while preserving confidentiality.</p><p><strong>Data: </strong>Dental patient data include radiographs, (cone beam) CTs, photographs, intraoral scans, tabular data, and electronic health records. These datasets are often heterogeneous, distributed across institutions, and subject to strict privacy regulations. Handling and sharing such sensitive data requires secure, privacy-preserving techniques to ensure compliance with legal and ethical standards.</p><p><strong>Sources: </strong>PubMed, Embase, Scopus, arXiv and Google Scholar were searched using keywords related to dentistry, data sharing, AI, and privacy-preserving techniques. Given the limited number of results relevant to dentistry, the search was extended to medicine. In parallel, we reviewed applicable regulatory frameworks such as the European Union (EU) General Data Protection Regulation (GDPR), HIPAA, EU AI Act, and European Health Data Space (EHDS).</p><p><strong>Study selection: </strong>We selected studies addressing data sharing in dentistry/medicine, de-identification, privacy-preserving techniques, and/or federated learning, as well as applicable regulatory frameworks. Most of the articles were peer-reviewed, but authoritative grey literature was included as well.</p><p><strong>Conclusions: </strong>This review summarized legal and technical aspects of dental data sharing to enable compliant multi-institutional collaboration. Beyond AI in dentistry, which was primarily emphasized, responsible data sharing is integral to FAIR practice and strengthens transparency and reproducibility across dental and medical research.</p><p><strong>Clinical significance: </strong>This review provides regulation-aligned guidance on de-identifying and sharing dental data, enabling compliant multi-institutional collaboration while protecting privacy. By promoting responsible AI development and reproducible research, it translates into more reliable care and greater patient trust in everyday clinical practice.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"106130"},"PeriodicalIF":5.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149254","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A new frontier in oral care with proteins and peptide infused in orally disintegrating film to prevent early dental erosion in vivo","authors":"Vinícius Taioqui Pelá ,&nbsp;Gustavo Cassalate da Silva ,&nbsp;Mariana Miranda de Brito ,&nbsp;Even Akemi Taira ,&nbsp;Carolina Ruis Ferrari ,&nbsp;Talita Mendes Oliveira Ventura ,&nbsp;Larissa Tercilia Grizzo Thomassian ,&nbsp;Flávio Henrique-Silva ,&nbsp;Eduardo Pereira de Souza ,&nbsp;Thiago Saads Carvalho ,&nbsp;Andrea Soares da Costa Fuentes ,&nbsp;Karina Fan ,&nbsp;Reinaldo Marchetto ,&nbsp;Adrian Lussi ,&nbsp;Marília Afonso Rabelo Buzalaf","doi":"10.1016/j.jdent.2025.106129","DOIUrl":"10.1016/j.jdent.2025.106129","url":null,"abstract":"<div><h3>Objective</h3><div>This study investigated the effectiveness of orally disintegrating films (ODFs) formulated with different proteins and peptide in minimizing early-stage dental erosion <em>in vivo</em>.</div></div><div><h3>Methods</h3><div>Twelve individuals participated in a six-phase crossover: placebo, 1 mg sodium fluoride (NaF), 1 mg sugarcane-derived cystatin (CaneCPI-5), 5 mg maquiberry-derived cystatin (MaquiCPI-3), 1 mg orange-derived cystatin (CsinCPI-2), and 0.37 mg statherin peptide (StN15pSpS). Following prophylaxis, participants placed the ODFs on their tongues until they dissolved, after the acquired pellicle was allowed to form over 2 h. An erosive challenge (biopsy, 1 % citric acid, 15 s) was conducted on the labial surface of the maxillary central incisors. Enamel loss was assessed using Relative Surface Reflection Intensity (%SRI), and calcium release in citric acid was measured using Arsenazo-III. Data were analyzed using Kruskal-Wallis and Dunn’s post hoc tests (<em>p</em> &lt; 0.05). A questionnaire assessed participants’ satisfaction and any side effects.</div></div><div><h3>Results</h3><div>The %SRI results demonstrated that MaquiCPI-3, CaneCPI-5, StN15pSpS, and NaF provided significantly greater enamel protection compared to the placebo (<em>p</em> &lt; 0.05). Calcium analysis showed that the ODFs containing CaneCPI-5 and MaquiCPI-3 resulted in similarly high calcium levels, whereas the placebo and NaF groups exhibited the lowest values, with no difference between them. The CsinCPI-2 and StN15pSpS groups displayed intermediate effects, with no significant differences compared to the other groups, except for CsinCPI-2, which presented significantly reduced calcium levels compared to the MaquiCPI-3 group (<em>p</em> &lt; 0.05). Participants reported satisfaction with the taste of the ODFs, found the procedures acceptable, and noted no adverse effects.</div></div><div><h3>Conclusions</h3><div>ODFs containing MaquiCPI-3, CaneCPI-5, and StN15pSpS effectively inhibited early dental erosion according to %SRI.</div></div><div><h3>Clinical Significance</h3><div>These findings highlight the potential of ODFs as innovative delivery systems for organic compounds aimed at preventing erosive tooth wear and promoting oral health.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106129"},"PeriodicalIF":5.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative Analysis of Full Crown Morphology Designed by Artificial Intelligence and Dental Technicians.","authors":"Ying Wang, Yi Li, Mingming Xu, Feng Liu","doi":"10.1016/j.jdent.2025.106131","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.106131","url":null,"abstract":"<p><strong>Objectives: </strong>To compare the morphological characteristics of full crowns designed by an experienced dental technician and a data-driven artificial intelligence (AI) system, with particular attention to their similarity to natural teeth.</p><p><strong>Methods: </strong>Twelve digital casts, including mandibular right second premolars, were collected, three-dimensional (3D) printed, and prepared by an experienced dentist. For each case, two crowns were independently designed by an experienced dental technician (ET) and the AI system. Morphological characteristics, including buccal and lingual cusp angle, buccal-lingual diameter, mesial-distal diameter, functional cusp wear facets, 3D similarity, and occlusal contact point counts, were compared among natural teeth, ET crowns, and AI crowns. Functional cusp wear and occlusal contacts were evaluated qualitatively, based on morphological observation and visual analysis under virtual articulating paper conditions. Statistical analysis was performed using one-way analysis of variance with least significant difference post-hoc testing, with the significance level set at α = 0.05.</p><p><strong>Results: </strong>Both AI crowns (56.2°±5.1°) and ET crowns (57.5°±6.3°) exhibited larger buccal cusp angles than natural teeth (45.7°±4.9°) (p < 0.05), while no significant differences were found in lingual cusp angles among the groups (p = 0.434, 0.607, 0.787). The buccal-lingual diameter of AI crowns closely matched natural teeth (p = 0.094), whereas ET crowns were significantly smaller than both AI crowns (p = 0.034) and natural teeth (p = 0.044). The mesial-distal diameter of AI crowns also showed no significant difference from natural teeth (p = 0.223), while ET crowns differed significantly from both groups (p = 0.047, 0.002). Although AI crowns exhibited slightly lower 3D discrepancy (0.43 ± 0.07) than ET crowns (0.48 ± 0.06), the difference was not statistically significant (p = 0.089). AI did not accurately reproduce functional cusp wear facets, whereas technician designs tended to overcompensate. Occlusal contact counts showed no significant differences among groups.</p><p><strong>Conclusions: </strong>AI systems can reproduce overall crown morphology to a degree comparable with experienced technicians but remain limited in replicating functional wear facets.</p><p><strong>Clinical implications: </strong>AI offers a practical and efficient tool for crown design, with potential to improve consistency and reduce manual workload in prosthodontics. However, further refinement is required before these systems can fully replicate functional morphological details for widespread clinical application.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"106131"},"PeriodicalIF":5.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A pilot study investigating the impact of cigarette smoking on oral nitrate-reducing bacteria within the oral microbiome","authors":"Tomas L. Nicholas ,&nbsp;Raul Bescos ,&nbsp;Amazon Doble ,&nbsp;Katie Muddiman ,&nbsp;Paul Kellett ,&nbsp;Abish S. Stephen ,&nbsp;Lisa du Toit ,&nbsp;Robert Witton ,&nbsp;Zoë L.S. Brookes","doi":"10.1016/j.jdent.2025.106127","DOIUrl":"10.1016/j.jdent.2025.106127","url":null,"abstract":"<div><h3>Objective</h3><div>To evaluate the impact of cigarette smoke on the activity and abundance of oral nitrate reducing bacteria (ONRB) in vivo and in vitro.</div></div><div><h3>Materials and methods</h3><div>An observational study comprising of eleven cigarette smokers and thirty-one non-smokers. A saliva and nitrate-rinse sample were collected from each participant to analyse salivary biomarkers and the activity and abundance of ONRB in vivo. Additionally, the effect of cigarette smoke on the nitrate-reducing activity of four Rothia species was investigated in vitro.</div></div><div><h3>Results</h3><div>The beta diversity of the oral microbiome was significantly different between smokers and non-smokers (<em>P</em> = 0.0063). Neisseria flavescens and Actinomyces oris were significantly higher in the saliva of smokers, however, Neisseria subflava, Neisseria oralis, Kingella denitrificans and Actinomyces georgiae were lower. Salivary nitrite levels were significantly lower in smokers (<em>P</em> = 0.034), along with a trend for decreased salivary pH (<em>P</em> = 0.058) and increased salivary thiocyanate (<em>P</em> = 0.018). In vitro exposure to cigarette smoke decreased the nitrate-reducing activity by Rothia species (<em>P</em> = 0.0046).</div></div><div><h3>Conclusions</h3><div>Smoking decreased salivary nitrite levels and had a species dependent effect on ONRB abundance in vivo and inhibitory effect on the nitrate-reducing activity of Rothia species in vitro.</div></div><div><h3>Clinical significance</h3><div>A ‘shift’ in the oral microbiome and inhibitory effect on nitrate reduction in smokers may contribute to an increased risk of oral and cardiovascular disease. Better understanding of this pathway may have the potential for development of interventions to decrease disease risk in this group.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106127"},"PeriodicalIF":5.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical study on the accuracy of wireless intraoral scanners for digital full arch impressions of dentate arches","authors":"Maximiliane Amelie Schlenz ,&nbsp;Luca Chillemi ,&nbsp;Bernd Wöstmann","doi":"10.1016/j.jdent.2025.106132","DOIUrl":"10.1016/j.jdent.2025.106132","url":null,"abstract":"<div><h3>Objective</h3><div>The aim of this clinical study was to update the literature on the scan accuracy (trueness and precision) of four modern wireless intraoral scanners (IOS) and to compare their performance with wired IOS and conventional impressions (CVI). A metallic reference aid was employed as the reference dataset.</div></div><div><h3>Methods</h3><div>Digital impressions were obtained from four wireless IOS (Dexis IS 3800 W, Medit i700, Primescan 2, and Trios 5), one wired IOS (Primescan AC), and one CVI in thirty patients. Scan data were analysed using 3D software, and CVI dental stone casts were evaluated using a coordinate measuring machine. Scan accuracy between the reference aid and the various impression systems was compared. Statistical analysis was performed using mixed-effects ANOVA models, with significance set at p &lt; 0.05.</div></div><div><h3>Results</h3><div>Statistically significant differences in trueness and precision were observed between the impression systems (p &lt; 0.05). A significant interaction between impression system and linear distance (p &lt; 0.05) indicated that performance varied depending on the length of scan path. The Dexis IS 3800 W and Medit i700 exhibited the greatest deviations, whereas the cloud-native Primescan 2 demonstrated comparable or superior accuracy to other impression systems.</div></div><div><h3>Conclusions</h3><div>Within the limitations of this clinical study, the overall accuracy of CVI remained high. Accuracy was influenced by both the impression system and the length of the scan path, with smaller deviations observed over short distances and increased inaccuracies over longer distances, particularly in diagonal and intermolar regions.</div></div><div><h3>Clinical significance</h3><div>Wireless IOS demonstrated statistically significant differences in certain cases, highlighting the importance of carefully evaluating the performance of each system individually.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106132"},"PeriodicalIF":5.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145149275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}