Journal of dentistry最新文献

{"title":"Automated detection and numbering of primary and permanent teeth in digital impressions of children using artificial intelligence.","authors":"Niels van Nistelrooij, Haline Cunha de Medeiros Maia, Lingyun Cao, Shankeeth Vinayahalingam, Bas Loomans, Maximiliano Sergio Cenci, Fausto Medeiros Mendes","doi":"10.1016/j.jdent.2025.105976","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105976","url":null,"abstract":"<p><strong>Objectives: </strong>Considering the importance of distinguishing between primary and permanent teeth in children with mixed dentition, this study aimed to develop and evaluate an automated method for segmenting and labelling primary and permanent teeth in digital impressions.</p><p><strong>Methods: </strong>716 digital impressions from 351 patients with primary or mixed dentitions were collected from the Netherlands, Brazil, and the 3DTeethSeg22 challenge dataset. The scans were annotated with tooth segmentations and primary and permanent teeth FDI numbers. A deep learning model was applied that combined large-context predictions for tooth labelling with high-resolution predictions for tooth segmentation. Using the collected scans, the model was trained and evaluated with five-fold cross-validation for tooth detection (F1-score), tooth segmentation (Dice score), and tooth labelling (macro-F1). Additionally, the model was trained and evaluated using the train-test split of the 3DTeethSeg22 challenge dataset.</p><p><strong>Results: </strong>The developed model achieved highly effective results for tooth detection (F1-score = 0.996), tooth segmentation (Dice = 0.969), and tooth labelling (macro-F1 = 0.989). Moreover, a digital impression was processed in under two seconds on average. Furthermore, the proposed method outperformed the top-ranked 3DTeethSeg22 challenge submission (score = 0.954 vs. 0.976) and was particularly effective for tooth labelling (tooth identification rate = 0.910 vs. 0.955). Failure cases revealed mistakes for unusual dental conditions or ambiguous tooth eruption patterns.</p><p><strong>Conclusions: </strong>A highly effective algorithm for tooth segmentation was developed to differentiate between primary and permanent teeth in digital impressions. This fast and accurate model can benefit dentists in documenting children's teeth during the mixed dentition stage.</p><p><strong>Clinical significance: </strong>The algorithm provides an accurate and reliable tool for AI-assisted identification and numbering of primary and permanent teeth in digital impressions obtained from children with mixed dentition, thereby enhancing clinical workflow, improving treatment planning accuracy, and facilitating communication with patients and caregivers.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105976"},"PeriodicalIF":4.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of extraoral scan body design on accuracy of scans recorded using four intraoral and one desktop scanner, with and without AI features: An In Vitro Study.","authors":"Panagiotis Ntovas, Ourania Ladia, Abdul B Barmak, John C Kois, Marta Revilla-León","doi":"10.1016/j.jdent.2025.105970","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105970","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;The aim of this in vitro study was to evaluate the impact of extraoral scan body (ESB) design on the scanning accuracy of a digitized facebow fork along with the attached ESB, using four intraoral scanners (IOS) and one extraoral desktop scanner (EOS), with and without the assistance of the available integrated artificial intelligence (AI) tools.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;One facebow fork and 4 ESBs were additively manufactured. The ESB designs included three different geometries: cube, ball, and rectangle. Each design was fabricated using a gray-colored resin. Four 6-mm-diameter gauge balls were affixed to the facebow fork, and five were attached to each ESB. A printed maxillary cast was initially secured to the facebow fork using an interocclusal registration material and subsequently detached. Each ESB was individually attached to the facebow fork and digitized 10 times using each of the four IOS devices (Aoralscan 3, i700, Primescan, and Trios 5) as well as one laboratory scanner (T710). For the Aoralscan 3, i700, and Trios 5 devices, scans were conducted both with and without the use of AI-assisted scanning features. To establish a reference dataset, each assembled ESB was also scanned using an industrial-grade scanner (Atos Q 3D 12M). Accuracy was assessed by comparing the experimental scans to the reference scan, measuring both linear distances between the gauge balls and angular deviations of the planes defined between the facebow fork and each ESB. Trueness was statistically analyzed using one-way ANOVA and Tukey's pairwise multiple comparison tests (α = .05). Precision was evaluated using Levene's test for equality of variances, followed by pairwise comparisons using the Wilcoxon rank-sum test with continuity correction (α = .05).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;There was a significant difference in both trueness and precision among the evaluated ESBs, when scanned using the evaluated IOSs (P&lt;.05). The laboratory scanner demonstrated higher overall accuracy compared to the IOSs (P&lt;.05), remained consistent regardless of the ESB's design and color (P&gt;.05). The AI-assisted tool provided by the Trios 5 improved the trueness of extraoral ESB digitization.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;The type of IOS affected the accuracy of the digitized ESB. The design and the color of the ESB impacted scanning accuracy, only when IOSs were used. ESBs with larger dimensions and more complex geometries posed significant challenges for certain IOSs, making in some cases their digitization impossible. The effectiveness of integrated AI-assisted scanning tools varied among devices, producing either beneficial or adverse effects depending on the specific IOS system.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Clinical significance: &lt;/strong&gt;ESBs can assist in both the superimposition and orientation of the virtual patient representation. However, as the size and geometric complexity of these devices increase, the use of a laboratory scanner is re","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105970"},"PeriodicalIF":4.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clear aligner therapy for minimally invasive dentistry: A scoping review.","authors":"Oana Elena Burlacu Vatamanu, Zaid Alzyoud, Bahaaeldeen M Elgarba, Rocharles Cavalcante Fontenele, Corina Marilena Cristache, Reinhilde Jacobs","doi":"10.1016/j.jdent.2025.105968","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105968","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a scoping review on the current applications of clear aligner therapy (CAT) in minimally invasive restorative and esthetic dentistry, and to explore available software for pre-restorative and esthetic CAT treatments.</p><p><strong>Data and sources: </strong>A systematic electronic literature search was performed in PubMed, Embase, Web of Science, Cochrane Library, and Scopus, alongside grey literature up to May 2024. Studies on CAT were included based on independent evaluation by two reviewers. Available CAT-related software was assessed up to May 2024.</p><p><strong>Study selection and results: </strong>Out of 1,847 articles, 21 studies were selected for review. Eleven focused on pre-restorative treatment, while 10 addressed esthetic outcomes. Ten aligner software programs were identified for short-term CAT use. CAT was particularly prominent in the preoperative phase for digital restorative planning, prosthetic and implant placement, and esthetic treatments.</p><p><strong>Conclusions: </strong>This scoping review mapped the current literature on short-term clear aligner systems for potential use in minimally invasive dentistry, by focusing on tooth alignment before restorative and esthetic interventions. The existing evidence is largely case-based and limited in quality, underscoring the need for further large-scale, methodologically rigorous studies to validate current findings and support the development of standardized clinical protocols.</p><p><strong>Clinical significance: </strong>Short-term CAT is increasingly being adopted as a preoperative stage in restorative and esthetic dentistry, providing rapid and effective results while maintaining a minimally invasive treatment strategy.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105968"},"PeriodicalIF":4.8,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of arginine-based synbiotics on multispecies biofilm.","authors":"Akhila Pudipeddi, Mohammed Nadeem Bijle, Cynthia Yiu","doi":"10.1016/j.jdent.2025.105974","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105974","url":null,"abstract":"<p><strong>Objective: </strong>To examine the effect of arginine (Arg)-based synbiotics on multispecies biofilm.</p><p><strong>Methods: </strong>In vitro biofilms (Streptococcus mutans UA159, S. gordonii DL1, S. sanguinis DSS-10) were grown on HA discs under anaerobic conditions (37°C, 5% CO₂, 24 h) and treated with: (1) Arg (0.25%, 0.5% w/v.), (2) Lacticaseibacillus rhamnosus GG (LRG) at 10⁷ CFU/mL, or (3) their combinations, 2× daily for 3 days. At 96 h, biofilm matrix components (exoproteins, eDNA, and carbohydrates) and microbial viability (confocal microscopy and PMA-qPCR) were quantified. Relative gene expression analysis was also conducted with species-specific genes (gtfB, sagP, arcA, argG, argH).</p><p><strong>Results: </strong>For carbohydrates, no significant difference was identified among treatment groups (p>0.05). Protein content for 0.5% Arg+LRG was significantly lower than LRG (p<0.05). The lowest eDNA content was observed in LRG (p<0.05); while eDNA content of 0.5% Arg+LRG, was similar to 0.5% Arg and control (p>0.05). Using confocal imaging, the highest proportion of live cell was found in 0.5% Arg+LRG (p<0.05), followed by 0.25% Arg+LRG, 3-D biofilm imaging demonstrated increased biomass with smoother architecture in biofilms treated with 0.5% Arg+LRG (p<0.05). 0.5% Arg+LRG significantly enhanced growth of commensal streptococci (S. gordonii, S. sanguinis) compared to monotherapies and control, while also reducing viability of S. mutans compared to control (p<0.05). Gene expression analysis revealed downregulation of S. mutans virulence (gtfB) and upregulation of commensal metabolism (sagP, arcA) for 0.5% Arg+LRG (p<0.05).</p><p><strong>Conclusion: </strong>The 0.5% Arg+LRG synbiotics uniquely integrates ecological modulation by regulating biochemical matrix components, promoting commensal enrichment and suppressing cariogenic pathogens.</p><p><strong>Clinical significance: </strong>A deliverable Arg-LRG synbiotics for caries prevention addresses a global public health priority. This strategy aligns with microbial homeostasis principles, presenting a novel paradigm for caries prevention. The Arg-LRG synbiotics can counter the limitations of fluorides to establish a diverse oral microbiome, imparting an ecologically driven approach to caries prevention.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105974"},"PeriodicalIF":4.8,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of battery levels and transmission distances on the accuracy and scan time of wireless intraoral scanners in complete-arch scans: An in vitro study.","authors":"Yong-Qing Guo, Kai-Jin Lin, Zi-En Wang, Hao Yu","doi":"10.1016/j.jdent.2025.105975","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105975","url":null,"abstract":"<p><strong>Objectives: </strong>This study explored the effects of battery levels and transmission distances on the accuracy and scan time of wireless intraoral scanners (IOSs) during complete-arch scans.</p><p><strong>Methods: </strong>A maxillary complete-arch typodont was used as a master model. Two wireless IOSs (Trios 4 wireless [TR4] and Trios 5 [TR5]; 3Shape A/S, Denmark) were evaluated across 4 battery levels (1∼25%, 26∼50%, 51∼75%, and 76∼100%) and 3 transmission distances (0.8±0.5 m, 2.0±0.5 m, and 4.0±0.5 m). A reference standard tessellation language (STL) file was generated by digitizing the master model with a laboratory scanner (InEos X5; Dentsply Sirona, USA). A total of 480 experimental STL files (n=20) were generated, and the corresponding scan time were recorded. Scanning accuracy (trueness and precision) was assessed by calculating the root mean square (RMS) deviation via Geomagic Control X. Two-way ANOVA was performed to analyze the data (α=0.05).</p><p><strong>Results: </strong>Battery level and transmission distance significantly affected the trueness and scan time (p<0.05). The least distortion was observed at low battery levels (1∼25%) and the most distant ranges (4.0±0.5 m) (TR4: 71.64±16.16 µm and TR5: 57.94±10.96 µm), whereas the fastest scans occurred at high battery levels (76∼100%) and close distances (0.8±0.5 m) (TR4: 54.20±4.51 s and TR5: 48.65±4.45 s). The scanning precision was independently influenced by both factors (p<0.05), with the highest precision at high battery levels (76∼100%) and close distances (0.8±0.5 m) (TR4: 54.92±5.24 µm and TR5: 63.88±12.86 µm).</p><p><strong>Conclusions: </strong>Moderate transmission distances (2.0±0.5 m) did not impair scanning trueness, even at lower battery levels (1∼25%). However, maintaining battery levels above 50% is recommended for optimal scanning accuracy and efficiency.</p><p><strong>Clinical significance: </strong>This study highlights the importance of optimizing transmission distances and battery levels to increase the performance of wireless IOSs in complete-arch scanning workflows.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105975"},"PeriodicalIF":4.8,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital post scan with three intraoral scanning systems – An in vitro study","authors":"Kay-Arne Walther,&nbsp;Sarah Marie Reich,&nbsp;Bernd Wöstmann,&nbsp;Jonas Adrian Helmut Vogler","doi":"10.1016/j.jdent.2025.105971","DOIUrl":"10.1016/j.jdent.2025.105971","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of this study was to investigate the feasibility of digital post scan (DPS) with three different intraoral scanners (IOS) and to evaluate the light reaching the apical part of the preparation, considering the influence of the type of tooth and adjacent teeth.</div></div><div><h3>Methods</h3><div>50 clinical cases treated with post and core (PC) were used for 3D printing of the dataset of DPS with a hole at the apical part of the preparation by virtual construction and nesting. The models covered the sensor of a luxmeter leaving only the hole for measuring the amount of light during DPS (lux-value) with Primescan (PRI), Trios 5 (TRI) and Medit i700 (MED). Feasibility of DPS was evaluated by the percentage of surface deviating &lt;50 µm from PRI (TRI/PRI, MED/PRI) in an analysis software. Moreover, a possible influence of the type of tooth that was treated with PC on DPS was evaluated. Statistical analysis was conducted using ANOVA with a significance level of <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>Highly significant differences (<em>p</em> &lt; 0.001) were found for the light reaching the apical part of the preparation (lux-value) between PRI, TRI and MED (in decreasing order). Except from PRI, DPS was only feasible for TRI (100 % of surface deviation &lt;50 µm) in three cases without adjacent teeth, showing highly significant differences between TRI/PRI and MED/PRI (<em>p</em> &lt; 0.001). The type of tooth did not have a significant influence (<em>p</em> &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>The amount of emitted light with PRI linked to the larger capturing window in comparison to TRI and MED might increase the feasibility of DPS with PRI.</div></div><div><h3>Clinical Significance</h3><div>PRI can be recommended for DPS, whereas TRI and MED showed inferior results leading to unpredictable accuracy of fit of PC. The depth of focus given by the manufacturer of the IOS is not an indicator for the feasibility of DPS.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105971"},"PeriodicalIF":4.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of fused deposition modeling using biodegradable material: A comparative study with four resin-based additive manufacturing methods.","authors":"Yolanda Natali Raico Gallardo, Banu Karayazgan, Eduardo Mukai, Claudio Peña Soto, Cortino Sukotjo, Gabriel Nima","doi":"10.1016/j.jdent.2025.105972","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105972","url":null,"abstract":"<p><strong>Objective: </strong>The aim of this study was to evaluate the accuracy of fused deposition modeling (FDM) using a biodegradable polylactic acid (PLA) material in comparison to four resin-based additive manufacturing methods.</p><p><strong>Methods: </strong>A virtual maxillary arch was designed using a design software (DentalCAD, Exocad GmbH) and printed 10 times per group. Five additive manufacturing methods were used including: FDM, stereolithography (SLA), digital light processing (DLP), liquid crystal display (LCD), and PolyJet (PJ). Fifty printed casts were scanned using an intraoral scanner (Primescan, Dentsply Sirona), and STL files were compared to the original design using a metrology software (Geomagic Control X, 3D Systems). The 3D analysis was performed on the overall cast and in the anterior, right posterior and left posterior regions. Trueness was determined by calculating the mean root mean square (RMS) value, while precision was assessed using the standard deviation of the RMS values. Color maps were used for visual analysis. The accuracy data did not meet the assumptions of normality and homogeneity of variance; therefore, a generalized linear model (GLM) was applied as a robust parametric alternative, followed by Bonferroni-adjusted pairwise comparisons (p < 0.05).</p><p><strong>Results: </strong>The PJ technology demonstrated the highest trueness among all groups (57.35 ± 17.73 µm) across all 3 anatomic regions (p < 0.05). FDM and SLA showed comparable trueness. The lowest trueness was observed in the DLP (163.37 ± 56.06 µm) and LCD groups (151.27 ± 52.36 µm). In terms of precision, PJ demonstrated the highest values among all groups (54.92 ± 16.89 µm) across all 3 anatomic regions (p < 0.05), followed by SLA and FDM groups, with no statistically significant difference between them. The lowest precision was observed in the DLP and LCD groups. Color displacement maps revealed larger deviations in the occlusal areas for DLP, SLA, and LCD groups, characterized by both expansion and shrinkage. FDM group showed a distinct pattern of shrinkage in the anterior zone and expansion in occlusal areas.</p><p><strong>Conclusion: </strong>FDM with biodegradable PLA demonstrated accuracy comparable to PJ and SLA, highlighting its potential as a sustainable alternative for dental cast fabrication.</p><p><strong>Clinical significance: </strong>Incorporating biodegradable materials into 3D printing offers a valuable step toward more eco-friendly and cost-effective dental additive manufacturing solutions.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105972"},"PeriodicalIF":4.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bacteriophages for periodontal pathogens control: A systematic review","authors":"Felipe Gomes Dallepiane ,&nbsp;Malena Alejandro Coimbra Nogueira ,&nbsp;Lucas Menezes dos Anjos ,&nbsp;Gilberto De Souza Melo ,&nbsp;Bruno Henriques ,&nbsp;Gislaine Fongaro ,&nbsp;Ariadne Cristiane Cabral Cruz","doi":"10.1016/j.jdent.2025.105960","DOIUrl":"10.1016/j.jdent.2025.105960","url":null,"abstract":"<div><h3>Objectives</h3><div>Faced with the growing challenge of bacterial resistance to antibiotics, bacteriophages emerge as a promising alternative due to their specificity and ability to lyse specific bacteria. This systematic review aims to analyze the efficacy of bacteriophage therapy in controlling the growth of periodontal pathogen.</div></div><div><h3>Data sources</h3><div>The protocol was registered in PROSPERO (CRD42023479696). The review followed PRISMA guidelines, utilizing a PICOS framework. Studies were identified through searches in seven databases (Embase, LILACS, PubMed, SCOPUS, Web of Science, Google Scholar and ProQuest) up to November 2024.</div></div><div><h3>Study selection</h3><div><em>In vitro</em> studies were evaluating the use of bacteriophages for this purpose were considered eligible. References were selected through a two-phase process. RoBDEMAT was used to assess the risk of bias. The certainty of the cumulative evidence was evaluated using the GRADE criteria.</div></div><div><h3>Results</h3><div>Eight studies were included, all demonstrating bacteriophages are effective in controlling periodontopathogenic bacteria growth. Four periodontal pathogen bacteria were analyzed, including <em>Aggregatibacter actinomycetemcomitans</em> (<em>n</em> = 3), <em>Fusobacterium nucleatum</em> (<em>n</em> = 3), <em>Streptococcus gordonii</em> (<em>n</em> = 2), and <em>Porphyromonas gingivalis</em> (<em>n</em> = 1). Eleven different types of bacteriophages were described, including: S1249 (<em>n</em> = 2), ΦSG005 (<em>n</em> = 2), JD-Fnp1 (<em>n</em> = 1), <span>d</span>-Fnp2 (<em>n</em> = 1), JD-Fnp3 (<em>n</em> = 1), JD-Fnp4 (<em>n</em> = 1), JD-Fnp5 (<em>n</em> = 1), FNU1 (<em>n</em> = 1), Aabφ01 (<em>n</em> = 1), Aabφ01–1 (<em>n</em> = 1), and Fnp02 (<em>n</em> = 1). The predominant method for evaluating bacterial growth was optical density measurement (<em>n</em> = 7) colony-forming unit (CFU) (<em>n</em> = 3).</div></div><div><h3>Conclusion</h3><div>Bacteriophage therapy effectively controls periodontal pathogenic bacteria <em>in vitro</em>, offering a possibility promising strategy for treating periodontitis, especially in antimicrobial-resistant cases. However, further research is needed to validate these findings in more complex models, such as multispecies biofilms and clinical settings.</div></div><div><h3>Clinical significance</h3><div>This study underscores the potential of bacteriophages as an innovative and targeted alternative for managing periodontal disease.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105960"},"PeriodicalIF":4.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Complete arch implant capture using a photogrammetry algorithm and smartphone app: An in vitro study","authors":"Andrea Santamaría-Laorden,&nbsp;Alicia Martínez Marugán,&nbsp;Cristina Andreu-Vázquez,&nbsp;Jaime Orejas-Pérez","doi":"10.1016/j.jdent.2025.105969","DOIUrl":"10.1016/j.jdent.2025.105969","url":null,"abstract":"<div><h3>Objective</h3><div>To compare the accuracy of complete arch implant capture using two extraoral photogrammetry (PG) systems (PIC system® and PIC app®).</div></div><div><h3>Methods</h3><div>An edentulous cast with six multiunit abutment (MUA) analogs was digitised and 30 complete arch implant captures were performed by each PG system. Euclidean linear and angular measurements were obtained on the digitised reference model with a coordinate measuring machine (CMM) and were used to compare the discrepancies with the same measurements obtained using the PG devices. The Mann–Withney U test was used to analyse the trueness data, and the Levene test was used to analyse the precision values (α=0.05).</div></div><div><h3>Results</h3><div>The mean ± standard deviation results for the distance and angulation measurements obtained using the PIC system and PIC app, respectively (18.21 ± 12.21 μm and 0.10 ± 0.07 degrees, and 30.92 ± 20.88 μm and 0.16 ± 0.09 degrees, respectively). The mean differences between the PIC app® and PIC system® were 12.70 μm (95 % confidence interval [CI]: 10.47, 14.94; <em>p</em> &lt; 0.001) and 0.07 degrees (95 % CI: 0.05, 0.07; <em>p</em> &lt; 0.001) for the Euclidean linear and angular measurements, respectively. The PIC system® demonstrated a greater precision (lower variance, <em>p</em> = 0.035) for linear measurements; however, both extraoral PG systems exhibited similar precision (equal variances) for angular measurements (<em>p</em> = 0.112).</div></div><div><h3>Conclusions</h3><div>PIC system® exhibited greater trueness for linear and angular measurements and linear precision. However, the impact of these statistically significant differences may not be clinically relevant.</div></div><div><h3>Statement of Clinical Relevance</h3><div>The PIC system® has been reported as an accurate PG method for recording the three-dimensional implant positions in complete arch prostheses; however, high equipment costs limit its widespread adoption. With the PIC app®, smartphones provide the democratisation of the PIC system® using an accurate and cost-effective approach.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"161 ","pages":"Article 105969"},"PeriodicalIF":4.8,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144611759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adverse childhood experiences from birth to age 6 years and changes in dental caries experience from age 7 to 10 years.","authors":"Noora Jawad, Ali Golkari, Eduardo Bernabé","doi":"10.1016/j.jdent.2025.105966","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.105966","url":null,"abstract":"<p><strong>Objectives: </strong>To examine the association of the timing and accumulation of exposure to adverse childhood experiences (ACEs) from birth to age 6 years, with changes in dental caries from age 7 to 10 years.</p><p><strong>Methods: </strong>This was a longitudinal study using data from 7633 children in the Avon Longitudinal Study of Parents and Children (ALSPAC), Bristol, England. Experience of eight ACEs (physical, emotional and sexual abuse; parental mental illness, separation, substance misuse and conviction; and interparental violence) was determined from annual questionnaires completed by mothers and partners, from birth until age 6 years. ACEs were counted cross-sectionally (co-occurrence at every age) and longitudinally (accumulation). Dental caries was measured using child reports on the number of decayed and filled teeth at ages 7 and 10 years. Mixed-effects Poisson regression was used to model caries increments, adjusting for confounders.</p><p><strong>Results: </strong>The mean number of decayed and filled teeth was 1.06 (95%CI: 0.99, 1.12) at age 7 years, increasing to 1.47 (95%CI: 1.40, 1.54) at age 10 years. The accumulation of ACEs was associated with greater caries increments (Rate Ratio: 1.15, 95%CI: 1.02, 1.30). In terms of the timing of exposure to ACEs, only the co-occurrence of ACEs at ages 4 (RR=1.13, 95%CI: 1.03-1.23), 5 (1.13, 95%CI: 1.03-1.23) and 6 years (1.14, 95%CI: 1.03-1.27) was associated with greater caries increments.</p><p><strong>Conclusion: </strong>There was a dose-response relationship between the cumulative exposure to ACEs in the first 6 years of life and subsequent changes in dental caries. In addition, recent exposure to ACEs (4-6 years of age) seemed more relevant to child dental caries than earlier exposure.</p><p><strong>Clinical significance: </strong>Experience of adversity during childhood, such as child maltreatment and household dysfunction, can increase children's caries risk. This knowledge can help dentists identify vulnerable children or families during routine dental visits.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105966"},"PeriodicalIF":4.8,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}