Journal of dentistry最新文献

{"title":"Bioactive resin composite with the potential of ion exchange following selective carious lesion removal -A laboratory-based study","authors":"Hanan Ahmad,&nbsp;David Mills,&nbsp;Graham Davis,&nbsp;Aylin Baysan","doi":"10.1016/j.jdent.2025.106144","DOIUrl":"10.1016/j.jdent.2025.106144","url":null,"abstract":"<div><h3>Objectives</h3><div>This laboratory-based study aimed to assess the possible ion exchange within residual leathery dentine using a bioactive UDMA-based resin composite.</div></div><div><h3>Materials and methods</h3><div>A total of 45 extracted teeth with deep carious lesions were assessed using the International Caries Risk and Assessment System (ICDAS). After radiographical evaluation, six teeth (ICDAS 4–5) were subsequently selected. After randomisation of the samples into three groups, the carious lesion was removed, leaving a layer of leathery dentine. The samples in the test group were restored with UDMA-based resin composite (Cention Forte, Ivoclar Vivadent, Liechtenstein), whilst the sculptable resin composite (Tetric Prime, Ivoclar Vivadent, Liechtenstein) was used for the positive control group. In contrast, the negative control group received no treatment. Each sample was stored in simulated body fluid (SBF). The 3D non-destructive X-ray microtomography (XMT) subtraction methodology, scanning electron microscopy (SEM) and energy dispersive X-ray (EDX) were employed at different stages to assess the samples. XMT scans were carried out immediately following the placement of restorations, and after three weeks and three months. At the end of the study, the surface topography and composition were analysed with SEM/EDX.</div></div><div><h3>Results</h3><div>The quantitative analyses at these time points revealed an increase in Linear Attenuation Coefficient (LAC) (related to mineral density) following the placement of restoration in one test tooth. However, the other samples failed to show any evidence of ion exchange within the residual dentine. The SEM and EDX analyses showed that the UDMA-based resin composite released ions and formed an apatite-like phase after three months in the same test tooth.</div></div><div><h3>Conclusion</h3><div>After a three-month laboratory-based study, the bioactive resin composite demonstrated evidence of slight exchange of mineral ions within remaining carious lesions following the selective carious lesion removal in only one test tooth. Notably, an 'apatite-like' phase was formed after immersion in SBF in the same tooth.</div></div><div><h3>Clinical significance</h3><div>The integration of bioactive glass represents a significant innovation in dental restorative materials. The use of bioactive resin composites not only restores the tooth structure but also potentially inhibits further demineralisation and promotes remineralisation following the selective carious lesion removal.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106144"},"PeriodicalIF":5.5,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145228621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the accuracy of static and dynamic computer-assisted implant surgery in extraction sockets, encased healed sites, and distal extension: an in vitro study.","authors":"Thibaut Marceron, Abhishek Kumar, Anastasios Grigoriadis, Philippe Campan, Cathy Nabet, Antoine Galibourg","doi":"10.1016/j.jdent.2025.105985","DOIUrl":"10.1016/j.jdent.2025.105985","url":null,"abstract":"<p><strong>Objectives: </strong>This study compared the accuracy of static and dynamic computer-assisted implant surgery (CAIS) by measuring the magnitudes and directions of coronal, apical, and angular deviations across three experimental scenarios.</p><p><strong>Methods: </strong>An in vitro study was conducted on 33 maxillary models per group, using static (s-CAIS) or dynamic CAIS (d-CAIS). Each model included three experimental conditions: Extraction Socket (#21), Encased Healed Site (#23), and Distal Healed Site (#26). A total of 198 implants were placed (3 per model). Postoperative deviations were assessed using 3D superimposition. Three-way ANOVA compared deviation magnitudes; directional deviations were analysed using Student's t-test or Wilcoxon test.</p><p><strong>Results: </strong>d-CAIS demonstrated significantly higher accuracy than s-CAIS. Mean 3D deviations for s-CAIS versus d-CAIS were 0.74 ± 0.32 mm compared to 0.65 ± 0.33 mm at the platform, 1.33 ± 0.54 mm versus 0.69 ± 0.37 mm at the apex, and 3.45 ± 1.14° versus 1.27 ± 1.05° angularly. The Extraction Socket Site showed the largest deviations for both systems (p < 0.001). For the Distal Healed Site, d-CAIS exhibited significantly higher accuracy than s-CAIS (p < 0.001). Platform deviation showed no significant difference between techniques (p = 0.44). Directional analysis revealed consistent buccal deviations in extraction sockets for both systems and vestibular-mesial-apical deviation for s-CAIS in distal sites.</p><p><strong>Conclusions: </strong>The current in vitro study indicated that d-CAIS exhibited superior accuracy to static s-CAIS across all tested conditions. While both techniques remained within clinically acceptable deviation thresholds, anatomical challenges, particularly in extraction sockets and distal regions, significantly influenced the magnitude and direction of deviations.</p><p><strong>Clinical significance: </strong>In this in vitro setting, both static and dynamic CAIS achieved deviations within clinically acceptable limits, supporting their reliability in clinical practice. Extraction sockets represented the most challenging sites for both systems. In distal sites, the directional deviations observed with s-CAIS indicated a bending effect of the cantilevered guide, emphasising the need for improved distal support or reinforcement.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"105985"},"PeriodicalIF":5.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posterior partial crowns out of lithium disilicate with or without posts: A randomized controlled study at 9 years follow up.","authors":"Edoardo Ferrari Cagidiaco, Giulia Verniani, Denise Irene Karin Pontoriero, Ovidiu Ionut Saracutu, Daniele Manfredini, Marco Ferrari","doi":"10.1016/j.jdent.2025.106005","DOIUrl":"10.1016/j.jdent.2025.106005","url":null,"abstract":"<p><strong>Objective: </strong>These randomized controlled clinical aims to evaluate the long-term clinical performance of posterior lithium disilicate partial crowns used to restore endodontically treated teeth (ETT), with or without fiber post placement, over a 9-year period in patients who did not report any bruxism activities at baseline.</p><p><strong>Materials and methods: </strong>Participants were recruited at the University of Siena, Siena, Italy. Patient were≥18 years, in need for one partial crown on posterior teeth (molars and premolars) following endodontic treatment and with at least 50 % of the coronal structure remaining. Patients were randomly assigned to two groups: Group 1 received fiber posts for abutment build-up, and Group 2 did not. Lithium disilicate partial crowns were fabricated and adhesively cemented for both groups. Clinical and radiographic evaluations were conducted at baseline, 1, 2, 3, and 9 years. Failures were defined as post debonding/fracture, root fracture, crown dislodgement/fracture, or the presence of periapical lesion. Cox regression analysis was used to assess the influence of post placement and tooth type.</p><p><strong>Results: </strong>A total of 120 patients were enrolled. At the 9-year follow-up, survival of ETT ranged between 88.8 % in molars without post and to 85.7 % in premolars with no post. No statistically significant difference was observed regarding post placement or tooth type on failure rates (p > .05).</p><p><strong>Conclusion: </strong>The findings of the present clinical trial support the idea in patients with no report of bruxism, the insertion of a fiber post for the reconstruction of endodontically treated teeth with partial crown lithium disilicate in posterior teeth is not a necessary procedure.</p><p><strong>Clinical significance: </strong>When at least 50 % of coronal structure is maintained, fiber post placement does not significantly influence survival rates. Lithium disilicate partial crowns provide excellent long-term outcomes in restoring endodontically treated posterior teeth.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"106005"},"PeriodicalIF":5.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144753530","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GINGIVAL COLOR IN DENTISTRY: A SYSTEMATIC REVIEW.","authors":"Manuel Antonio Sanchez de Martín, Beatriz Párdal Peláez, Adrian Curto, Cristina Gómez-Polo","doi":"10.1016/j.jdent.2025.106143","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.106143","url":null,"abstract":"<p><strong>Objectives: </strong>To synthesize the available knowledge on gingival color and its relevance to aesthetics.</p><p><strong>Data: </strong>This systematic review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines.</p><p><strong>Sources: </strong>An electronic search was conducted in the Web of Science database using the keywords: gingivae, color, aesthetic, and their combinations. Only English-language articles published between 2014 and November 2024 were included.</p><p><strong>Study selection: </strong>The search strategy followed these steps: ALL=(gingival) OR ALL=(gingiva);ALL=(colour) OR ALL=(color);ALL=(esthetic) OR ALL=(aesthetic); Finally, the combined search was #1 AND #2 AND #3. Opinion articles, books, clinical cases, and prospective or retrospective studies were excluded. From an initial database of 275 results, and after applying exclusion criteria and full-text review by the authors, 21 studies were included.</p><p><strong>Conclusions: </strong>Gingival color remains underexplored, with insufficient literature to draw robust conclusions. Recording, communicating, and reproducing gingival color is inherently complex. No studies to date have quantified gingival color changes in longitudinal designs. Some publications have highlighted chromatic discrepancies between natural gingiva, restorative materials, and even between similarly named gingival materials. Nearly all available studies are cross-sectional, limiting understanding of gingival color evolution over time. Multicenter longitudinal studies are needed, using representative populations of various racial backgrounds and standardized spectrophotometric protocols.</p><p><strong>Clinical significance: </strong>Despite advances over the past decade, studies addressing gingival color show a high degree of heterogeneity, both in vivo and in vitro, making direct comparisons difficult. Additionally, the lack of standardized methodologies in terms of measurement areas, racial and demographic characteristics, devices, inclusion criteria, and material diversity has left gingival color as an underexplored and poorly understood phenomenon. Coordinated efforts between manufacturers, commercial entities, and researchers are essential to generate reliable and clinically relevant knowledge for gingival restoration.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"106143"},"PeriodicalIF":5.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determinants of removable partial denture success in patients’ perspectives","authors":"Siraphob Techapiroontong ,&nbsp;Supachai Chuenjitwongsa ,&nbsp;Nareudee Limpuangthip","doi":"10.1016/j.jdent.2025.106145","DOIUrl":"10.1016/j.jdent.2025.106145","url":null,"abstract":"<div><h3>Objective</h3><div>To provide insight into how successful removable partial dentures (RPDs) are determined from the patients’ perspectives, as well as associating factors that affect success with a qualitative approach.</div></div><div><h3>Methods</h3><div>A qualitative study with case study methodology was conducted among 15 experienced RPD patients (mean age: 65.2 ± 8.4 years old). Demographic data were collected using questionnaires, while oral status and denture characteristics were clinically examined by the investigators. Face-to-face interviews were performed until data saturation was achieved. Demographic data were analyzed with descriptive statistics. Content and framework analyses were used to identify recurring themes relevant to determinants of RPD success from the transcribed interviews. A preliminary questionnaire was conducted to validate the framework and to determine the difference from neutral agreement score.</div></div><div><h3>Results</h3><div>Four main themes related to RPD success included: (1) individual background and experience, (2) treatment expectations, (3) improvement of oral health-related quality of life (OHRQoL) and satisfaction, and (4) treatment acceptance. These themes, especially acceptance, provided a more comprehensive understanding of RPD success. Treatment satisfaction was closely related to OHRQoL improvements, and acceptance emerged as how patients adapted to RPD limitations over time. Significant agreement was found on four of the proposed associations.</div></div><div><h3>Conclusions</h3><div>This study highlights the importance of considering patient background, realistic expectation-setting, dentist-patient communication, and adaptation support in RPD treatment. A revised diagram of RPDs’ determinants of success was proposed to guide clinicians in enhancing patient-centered care.</div></div><div><h3>Clinical Significance</h3><div>To achieve RPD treatment success, patients’ prior experiences should be identified and incorporated into RPD treatment plan, aligning with their individual expectations. Effective communication between patients and clinicians is crucial, involving comprehensive discussion about RPD functionality, potential limitations, and establishing realistic expectations. Addressing the adaptation process following treatment is essential to enhance patient satisfaction and acceptance. Post-treatment OHRQoL assessments during maintenance periods are required to provide long-term patient support.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106145"},"PeriodicalIF":5.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The application of cold atmospheric pressure plasma in prosthodontics","authors":"Yixuan Dai ,&nbsp;Xin Sui ,&nbsp;Shuyi Huang ,&nbsp;Yaxuan Li ,&nbsp;Bowei Wang ,&nbsp;Zhihui Liu","doi":"10.1016/j.jdent.2025.106141","DOIUrl":"10.1016/j.jdent.2025.106141","url":null,"abstract":"<div><h3>Objective</h3><div>This review systematically summarizes recent advances in plasma applications for dentin bonding, antibacterial enhancement, and implant surface modification.</div></div><div><h3>Data</h3><div>A systematic literature search was conducted across four electronic databases: Medline via PubMed, Cochrane Library, Wiley Online Library, and Web of Science. The search was performed from inception until August 2025.</div></div><div><h3>Sources</h3><div>154 publications were included in this review.</div></div><div><h3>Study selection</h3><div>The keywords used included combinations of MeSH and free-text terms such as ‘cold atmospheric pressure plasma’, ‘CAP’, ‘dentin bonding’, ‘antibacterial’, and ‘implant surface modification’. Two reviewers independently screened titles and abstracts, followed by full-text evaluation. Disagreements were resolved by a third reviewer. Inclusion criteria were: (1) original research articles, (2) studies involving CAP in prosthodontics, (3) published in English. Exclusion criteria included: case reports, editorials, and conference abstracts.</div></div><div><h3>Conclusion</h3><div>CAP can enhance the penetration and polymerization of resin monomers in dentin bonding, improve bond strength, and reduce microleakage due to its highly active substances. Additionally, CAP has exhibited notable antibacterial properties, as its reactive oxygen and nitrogen effectively inactivate oral bacteria and biofilm, thereby reducing the likelihood of drug resistance. Furthermore, CAP treatment may enhance implant surface properties, promote osseointegration, lower infection risk, and promote soft-tissue healing.</div></div><div><h3>Clinical Significance</h3><div>CAP is anticipated to address the challenges encountered in prosthodontics, including dentin bonding, antimicrobial properties, and implant surface modification. Consequently, CAP is expected to provide an innovative solution for the functionalization and longevity of dental restorations with the prospect of future chairside application.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106141"},"PeriodicalIF":5.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145212784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of CAD/CAM-based subtractive versus digital light processing fabricated mono-block splints for TMD management: An in vitro study","authors":"Antong Wu ,&nbsp;Ping Li ,&nbsp;Astrid D. Bakker ,&nbsp;Janak L. Pathak ,&nbsp;Qingbin Zhang ,&nbsp;Wei Cao ,&nbsp;Richard T. Jaspers","doi":"10.1016/j.jdent.2025.106136","DOIUrl":"10.1016/j.jdent.2025.106136","url":null,"abstract":"<div><h3>Objectives</h3><div>A newly designed Mono-Block (MB) splint has demonstrated promising clinical potential for treating temporomandibular disorders (TMD). The accuracy of MB splint fabrication is critical to the effectiveness of TMD treatment; however, it remains insufficiently defined. This study aimed to investigate the impact of subtractive manufacturing (SM) and additive manufacturing (AM) technologies on the trueness and precision of MB splints.</div></div><div><h3>Methods</h3><div>Splint samples were fabricated using a representative AM technique (digital light processing, DLP) and an SM method (milling). Following fabrication, all samples were scanned and analyzed using 3D inspection software. Root mean square (RMS) values were measured to assess trueness and precision, and color maps were generated to detect deviations. Statistical analyses were conducted using Mann-Whitney U tests and unpaired <em>t</em>-tests.</div></div><div><h3>Results</h3><div>SM splints exhibited significantly higher trueness than AM splints in the maxillary and mandibular marginal areas and the mandibular intaglio surface (<em>p</em> <em>&lt;</em> <em>0.0001</em>). No significant difference was observed in the maxillary intaglio surface (<em>p</em> <em>=</em> <em>0.143</em>). Regarding precision, SM splints demonstrated greater precision in the mandibular marginal area (<em>p</em> <em>&lt;</em> <em>0.0001</em>), while AM splints exhibited higher precision in the maxillary marginal area (<em>p</em> <em>=</em> <em>0.004</em>). No significant differences in precision were found for the maxillary (<em>p</em> <em>=</em> <em>0.876</em>) and mandibular (<em>p</em> <em>=</em> <em>0.311</em>) intaglio surfaces.</div></div><div><h3>Conclusion</h3><div>The manufacturing method significantly influenced MB splint accuracy. SM splints exhibited superior trueness, while both fabrication methods demonstrated comparable precision. Accuracy was greater in the mandibular section and the intaglio surface compared to other areas.</div></div><div><h3>Clinical significance</h3><div>All splints produced by SM or AM manufacturing methods meet the clinical requirements. However, regarding accuracy, SM splints appear to be the preferred choice.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106136"},"PeriodicalIF":5.5,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206594","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pulpotomy for treating primary molars with clinical symptoms indicative of irreversible pulpitis: A prospective single-arm pilot study","authors":"Nebu Philip ,&nbsp;Mawlood Kowash ,&nbsp;Thikrayat Bani-Hani ,&nbsp;Osama El Shahawy ,&nbsp;Ahmad Issa ,&nbsp;Hanan Mohamed ,&nbsp;Mustafa Abdalla ,&nbsp;Suhad Jundi ,&nbsp;Sondos Albadri ,&nbsp;Mandeep Duggal ,&nbsp;Hani Nazzal","doi":"10.1016/j.jdent.2025.106140","DOIUrl":"10.1016/j.jdent.2025.106140","url":null,"abstract":"<div><h3>Objectives</h3><div>Assess the treatment outcomes and pain relief afforded by full pulpotomy in vital primary molars with clinical symptoms indicative of irreversible pulpitis.</div></div><div><h3>Methodology</h3><div>This study was designed as a multi-centre, single-arm, prospective clinical trial registered under ClinicalTrials.gov (NCT06149845). Fifty carious primary molars with clinical symptoms indicative of irreversible pulpitis and pulp intra-operatively assessed to be vital, underwent full coronal pulpotomy following a standardized procedural protocol. Haemostasis was achieved by moderately compressing a 2 % NaOCl-moistened sterile cotton pellet over the radicular pulp stumps for up to 6-minutes. A 2–3 mm layer of mineral trioxide aggregate (MTA) was placed as the pulpotomy medicament and the tooth restored with a pre-formed metal crown. Pre- and post-operative pain scores were evaluated using a validated five-point visual analogue scale (VAS). Clinical and radiographic outcomes were assessed after 6-months. Treatment outcome effects of potential prognostic factors like age, gender, tooth type, site of caries, haemostasis time, and furcal radiolucency were also analysed.</div></div><div><h3>Results</h3><div>Intra-group analysis of VAS pain scores revealed significant pain reduction 24-h and 7-d after the pulpotomy treatment procedure. The 6-month post-treatment clinical and radiographic success rates of the pulpotomised primary molars were 100 % and 93.9 %, respectively. No significant association was evident between treatment outcomes and the investigated variables.</div></div><div><h3>Conclusions</h3><div>The pain relief afforded and the 6-month clinical and radiographic outcomes indicate that MTA pulpotomy is a successful treatment option for vital primary molars clinically diagnosed with irreversible pulpitis.</div></div><div><h3>Clinical Significance</h3><div>This study strengthens the currently available evidence for pulpotomy to be considered as an alternate treatment modality for cariously exposed vital primary molars presenting with symptomatic irreversible pulpitis.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106140"},"PeriodicalIF":5.5,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reversal of root caries using fluoride toothpastes with or without bioactive glass - an in vitro study","authors":"Haoran Chen,&nbsp;Robert Hill,&nbsp;Aylin Baysan","doi":"10.1016/j.jdent.2025.106139","DOIUrl":"10.1016/j.jdent.2025.106139","url":null,"abstract":"<div><h3>Objectives</h3><div>To evaluate the effect of fluoridated toothpastes with or without bioactive glass on root caries.</div></div><div><h3>Materials and Methods</h3><div>A total of 94 extracted teeth with 128 root caries were assessed using visual-tactile assessments and light-induced fluorescence-evaluator (SoproLIFE) at baseline and after three months to determine the severity of lesions. Each lesion was randomly allocated into four groups: Group-1: Bioactive glass (BG) with 540 ppm fluoride, Group-2: 5,000 ppm fluoride, Group-3: 1,450 ppm fluoride, Group-4: Deionised water. Standardised tooth-brushing was performed twice a day. Samples were stored in remineralising solution (pH7) at 37°C. Raman spectroscopy and scanning electron microscopy (SEM) were conducted at three months.</div></div><div><h3>Results</h3><div>There was a significant decrease in severity index of root caries in treatment groups (<em>p</em>=0.03). 44% of lesions in Group-2 reversed and became hard (SI0), whilst 41% in Group-1, 38% and 19% of root caries in Groups-3 and 4 respectively reversed to SI0. The SoproLIFE results demonstrated that 25% of lesions in BG with 540 ppm fluoride, 19% in 5,000 ppm fluoride, whilst 16% in 1,450 ppm fluoride, 28% in deionised water group became hard. 3% of lesions became worse in deionised water group only. Raman spectroscopy indicated that phosphate content was highest in 5,000 ppm fluoride, followed by BG with 540 ppm fluoride&gt;1,450 ppm fluoride&gt;deionised water groups. SEM analyses showed partially/completely closed dentinal tubules in all toothpaste groups, however, tubules were exposed in deionised water group.</div></div><div><h3>Conclusion</h3><div>Within the limitations of this study, all toothpastes were potentially effective in hardening root carious lesions and remineralisation. 5,000 ppm fluoride had a superior effect in promoting remineralisation.</div></div><div><h3>Clinical significance</h3><div>All study toothpastes have potential benefits in arresting and reversing root caries. These findings can provide further evidence to support the development of updated guidelines for root caries.</div></div>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":"163 ","pages":"Article 106139"},"PeriodicalIF":5.5,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145191853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Deep Learning Method for Diagnosis of Oral Potentially Malignant Disorders.","authors":"Y Q Cao, J Y Zhang, M Lu, L J Shi, H X Dan, F D Zhu, P J Huang, G X Zhang, H J Zhang, Q M Chen","doi":"10.1016/j.jdent.2025.106138","DOIUrl":"https://doi.org/10.1016/j.jdent.2025.106138","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to develop and validate a two-stage deep learning method for diagnosing oral potentially malignant disorders (OPMDs). We also compared its diagnostic performance with that of clinicians at different levels of seniority and evaluated its utility as a clinical decision support tool.</p><p><strong>Methods: </strong>A two-stage deep learning method was developed. CLA OPMD-OOML was designed to differentiate OPMDs from other oral mucosal lesions (OOML), while CLA OPMDs was designed to classify specific OPMD subtypes. The method was trained on an internal dataset (ZJUSS, n = 3,305), and its generalizability was evaluated on two external multicenter datasets (WCHS and CS-SJTU, n = 1,756). In a blinded, two-step comparative study, nine clinicians (junior, intermediate, and senior groups) performed diagnoses independently and then with AI assistance.</p><p><strong>Results: </strong>The method significantly outperformed all clinician groups, achieving higher F1 scores in both CLA OPMD-OOML (89.9% vs. 78.4-82.6% for clinicians) and CLA OPMDs (92.2% vs. 77.7-80.0% for clinicians). It showed robust generalizability on the two external datasets, with F1 scores of 87.3% and 86.9% for CLA OPMD-OOML and 75.9-83.0% for CLA OPMDs. With AI assistance, the diagnostic precision of junior and intermediate clinicians increased by 10.8% and 5.9%, respectively, raising the junior group's performance to the level of senior clinicians.</p><p><strong>Conclusions: </strong>The developed two-stage deep learning method demonstrated diagnostic performance comparable to or exceeding that of experienced clinicians in classifying OPMDs from clinical images. It functions as a powerful assistive tool that substantially enhances the diagnostic capabilities of junior and intermediate clinicians.</p><p><strong>Clinical significance: </strong>This AI method has the potential to serve as a reliable tool for large-scale early screening of OPMDs, particularly in regions with limited access to specialist dental care. It can also serve as a valuable training and decision support system for junior clinicians, helping to standardize diagnostic accuracy and improve patient outcomes through timely and accurate detection. A supplemental appendix to this article is available online.</p>","PeriodicalId":15585,"journal":{"name":"Journal of dentistry","volume":" ","pages":"106138"},"PeriodicalIF":5.5,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145185950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}