International Urogynecology Journal最新文献

{"title":"Evaluation of the Efficacy and Safety of Hyaluronic Acid Injection for Volume Restoration of the Labia Majora: ESOLANE study.","authors":"Fabien Boucher, Catherine Eychenne, Brice Gurriet, Nicolas Berreni, Juan Berrocal, Phryné Foulc, Alain Levy, Adriana Guzman-Ruiz, Barbara Hersant","doi":"10.1007/s00192-025-06094-1","DOIUrl":"https://doi.org/10.1007/s00192-025-06094-1","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Labia majora atrophy and protrusion of the labia minora beyond the labia majora is a concern for an increasing number of women who consider it aesthetically and, sometimes, functionally unsatisfactory. The ESOLANE study was a multicenter clinical investigation designed to collect effectiveness and safety data on DESIRIAL® PLUS injected subcutaneously in the labia majora in participants seeking labia majora volume deficits correction.</p><p><strong>Methods: </strong>A prospective, uncontrolled, open-label multicenter study was conducted between November 2019 and December 2021. Seventy-three women with labia majora hypotrophy or atrophy and requesting labia majora volume restoration were enrolled and 72 were treated. Outcome measures were collected at baseline, then 4, 12, 24, 36, and 52 weeks post treatment. Primary endpoint was the proportion of patients' who reported aesthetic improvement on the global aesthetic improvement scale (GAIS) 12 weeks after initial injection. Secondary endpoints were assessments of patients' and investigators' who reported GAIS, patient sexual function and physical symptoms, patient satisfaction, and safety.</p><p><strong>Results: </strong>According to the patients' who reported GAIS, 97% rated themselves as improved 12 weeks following the initial treatment. Improvement levels were high throughout the 52-week follow-up period with rates > 92%. Improvements were also confirmed on investigators' assessments with rates > 86%. Furthermore, patients reported significantly improved sexual function, symptom reduction, and high satisfaction. DESIRIAL® PLUS was well tolerated.</p><p><strong>Conclusions: </strong>DESIRIAL® PLUS is an effective and safe treatment option in patients with labia majora hypotrophy or atrophy. This effect goes beyond aesthetic improvement, as treatment was associated with improvement in patients' physical symptoms and sexual function.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice Toward Urinary Incontinence Among Physically Active Women.","authors":"Jucyara da Silva Coelho, José Ananias Vasconcelos Neto, Camila Teixeira Moreira Vasconcelos, Simony Lira do Nascimento, Flávio Mendes Alves","doi":"10.1007/s00192-025-06093-2","DOIUrl":"https://doi.org/10.1007/s00192-025-06093-2","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Urinary incontinence (UI) is a prevalent condition that can impact the quality of life of physically active women. This study aimed to evaluate knowledge, attitudes, and practices (KAP) related to UI among women who exercise in gyms.</p><p><strong>Methods: </strong>A cross-sectional observational study was carried out from March to July 2022, in gyms located in the city of Parnaíba, in northeastern Brazil with physically active women. For data collection, the International Physical Activity Questionnaire (IPAQ), the International Incontinence Consultation Questionnaire-Short Form (ICIQ-SF), a specific KAP-UI questionnaire and a standardized form for sociodemographic, gynecological and obstetric data were used. The Mann-Whitney test, Fisher's exact test and chi-square tests were performed to analyze differences between subgroups formed on the basis of the presence or absence of urinary incontinence.</p><p><strong>Results: </strong>The research included 256 female participants with a median age of 33 (18-67) years, good education (≥ 12 years of studies) (97%), majority single (60%), and monthly income greater than US$ 235.51 (68%). The prevalence of UI was 43% (n = 110) with a moderate impact on quality of life. Among the participants, 51.8% had adequate knowledge and 98.7% demonstrated positive attitudes toward UI. However, only 29.5% adopted treatment practices, while preventive practices were carried out by only 16.4%. Factors significantly associated with inadequate knowledge included lower levels of education (p = 0.030), single marital status (p = 0.031), monthly income below US$235.51 (p = 0.019), and bodybuilding as the main physical activity (p = 0.039). Conversely, women who were highly physically active were more likely to have adequate knowledge. Significant associations were found between adequate knowledge and preventive and therapeutic practices (p = 0.003), as well as between inadequate knowledge and inadequate practices.</p><p><strong>Conclusions: </strong>Although only half of the participants had adequate knowledge about UI, the majority demonstrated a positive attitude toward the health problem. However, preventive practices were low among women without UI, as was the search for treatment among those with UI. Factors such as age, education, marital status, income, type and level of physical activity were linked to knowledge and preventive and treatment practices. Adequate knowledge was associated with effective preventive and therapeutic practices for IU by physically active women.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic Venous Disorders are Associated with an Earlier Age-of-Onset in Females with Interstitial Cystitis/Bladder Pain Syndrome.","authors":"Amr S El Haraki, Rory Ritts, Mary Namugosa, John Regan, Benjamin Daniel, Robert Evans, Stephen J Walker","doi":"10.1007/s00192-025-06088-z","DOIUrl":"https://doi.org/10.1007/s00192-025-06088-z","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Pelvic venous disorders (PVDs) are a group of inter-related pathological diagnoses that can present with a range of symptoms including pelvic and urinary symptoms similar to those seen in interstitial cystitis/bladder pain syndrome (IC/BPS). The relationship between PVDs and IC/BPS in humans has yet to be evaluated. This study's objectives are to determine the prevalence of PVD in patients with IC/BPS and to identify associated characteristics.</p><p><strong>Methods: </strong>Charts from our study on patients with IC/BPS undergoing hydrodistension (HOD) were screened for those with an MRI or CT scan of the abdomen/pelvis. Imaging findings suggestive of PVD were noted. Information regarding anesthetic bladder capacity (BC), Hunner lesion (HL) status, results for validated IC/BPS symptoms, and patient reports of comorbid non-urological associated syndromes (NUAS) known to co-occur with IC/BPS were collected.</p><p><strong>Results: </strong>A total of 133 patients with IC/BPS had the appropriate studies for a diagnosis of PVD, of which 64 (48.1%) were positive. PVD-positive patients were younger at IC/BPS diagnosis (35.36 ± 12.47 vs 42.32 ± 14.53; p = 0.004), younger at most recent HOD (45.59 ± 13.18 vs 53.32 ± 13.71; p = 0.001), and had a lower BMI (27.88 ± 7.35 vs 32.18 ± 9.29; p = 0.004). No significant differences were noted in age at earliest HOD, smoking status, average BC, HL status, total number of HOD, total NUAS, or any of multiple reported comorbidities. Additionally, none of the average IC/BPS symptom scores were significantly different.</p><p><strong>Conclusions: </strong>Imaging findings suggestive of PVD are common in patients with IC/BPS and may be associated with an earlier onset of disease.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Randomized Controlled Trial of Instillation Protocols Prior to Intradetrusor OnabotulinumtoxinA.","authors":"Sarah A Ward, Annliz Macharia, Michele R Hacker, Eman A Elkadry, William D Winkelman","doi":"10.1007/s00192-025-06080-7","DOIUrl":"https://doi.org/10.1007/s00192-025-06080-7","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Achieving adequate pain relief is crucial for intradetrusor onabotulinumtoxinA treatments for idiopathic overactive bladder in office settings. The objective of this study was to determine whether buffered lidocaine bladder instillation provides better pain control than standard lidocaine prior to intradetrusor onabotulinumtoxinA injections.</p><p><strong>Methods: </strong>We conducted a prospective, double-blind, randomized controlled trial comparing two protocols. The standard protocol used a pre-procedure instillation of 50 ml of 1% lidocaine and 50 ml of 0.9% saline. The buffered lidocaine protocol used 50 ml of 1% lidocaine, 45 ml of 0.9% saline, and 5 ml of 8.4% sodium bicarbonate. Both protocols were administered 20 min before onabotulinumtoxinA injections. Female patients with a primary diagnosis of idiopathic overactive bladder were randomized. The primary outcome was procedural pain using a visual analog scale (VAS) measured in millimeters, with secondary outcomes of patient satisfaction and willingness to repeat the procedure.</p><p><strong>Results: </strong>Of the 76 patients enrolled, 38 were randomized to each group. Data were analyzed for 37 patients in the buffered lidocaine group, and 36 in the standard lidocaine group. Both groups had comparable baseline characteristics. There was no difference in median pain measured by VAS between the buffered (16 [9-40]) and standard (25 [15-55]) protocols (p = 0.21). The buffered group reported a higher, though not statistically significant, satisfaction rate (68% vs 39%, p = 0.08).</p><p><strong>Conclusion: </strong>Intradetrusor onabotulinumtoxinA injections are generally well tolerated among women with idiopathic overactive bladder. No difference was found between protocols, suggesting that buffered lidocaine instillation may not improve pain control among women with idiopathic overactive bladder, although we had insufficient power to detect a difference of the observed magnitude.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Short-Term Complications Following Transvaginal Sacrospinous Ligament Rectopexy: A Retrospective Cohort Study.","authors":"Alireza Hadizadeh, Henry H Chill, Angela Leffelman, Claudia Paya-Ten, Cecilia Chang, Jungeun Lee, Roger P Goldberg, Steven D Abramowitch, Ghazaleh Rostaminia","doi":"10.1007/s00192-025-06098-x","DOIUrl":"https://doi.org/10.1007/s00192-025-06098-x","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Obstructed defecation syndrome (ODS) affects over 12% of middle-aged women, characterized by excessive straining, incomplete evacuation, and splinting. Current surgical options such as ventral mesh rectopexy, though effective, involve risks associated with mesh use and abdominal entry. This study evaluates the short-term complications of transvaginal sacrospinous ligament rectopexy.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted at a tertiary medical center, including patients over 21 years who underwent transvaginal sacrospinous ligament suture rectopexy for ODS from January 2018 to May 2024. Demographic, intraoperative, and 30-day postoperative complication data were collected.</p><p><strong>Results: </strong>A total of 190 patients with a mean age of 62.3 years underwent transvaginal sacrospinous ligament suture rectopexy. Intraoperative complications were rare, with four rectal injuries: two occurred during posterior dissection, one due to aggressive posterior repair, and another was discovered during exploration for postoperative pain. All rectal injuries were managed successfully. One patient experienced significant intraoperative bleeding, resulting in a hematoma that required evacuation 5 days later. Postoperative urinary retention was the most common complication, affecting 29.8% of patients. This was associated with concurrent procedures, such as mid-urethral sling placement and anterior colporrhaphy. Reoperation within 30 days was necessary for six patients (3.7%): two for urinary retention due to sling-related issues, two for sacrospinous pain necessitating suture removal, and two for vaginal bleeding related to hematoma formation. No cases of surgical site infection, sepsis, or mortality were observed.</p><p><strong>Conclusions: </strong>Transvaginal sacrospinous ligament suture rectopexy appears to be a safe alternative for ODS treatment, with low short-term complication rates.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143523260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Infections in the Culture of Catheter Urine Specimens and Bladder Biopsies in Women Undergoing Cystoscopy.","authors":"Bernadette Lemmon, Vijaya Gopalan, Akshaya Mathialagan, Livia Khullar, Vik Khullar","doi":"10.1007/s00192-025-06086-1","DOIUrl":"https://doi.org/10.1007/s00192-025-06086-1","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Urinary tract infections (UTIs) are one of the most common reasons for seeking medical review worldwide. Women are disproportionately affected, with a life-time incidence of 50%. Women presenting with clinical symptoms of UTI such as dysuria and urinary frequency can often have negative urine culture results, especially if they have been taking multiple courses of antibiotics. This can make the diagnosis and management of recurrent or chronic UTI challenging. In this study we compared the culture results of urine and bladder tissue in women undergoing rigid cystoscopy presenting with lower urinary tract symptoms. We hypothesise that a biopsy of the bladder wall might be more likely to reveal a causative uropathogen on culture than urine.</p><p><strong>Methods: </strong>Women had clean-catheter urine samples sent for urine culture and then bladder biopsies taken at cystoscopy cultured for uropathogens. Culture results from urine and bladder tissue were analysed and compared.</p><p><strong>Results: </strong>We found that under 10% of urine cultures were positive (n = 30), whereas 51% of bladder tissues cultures grew a uropathogen (n = 155). Analysis showed that the culture results of urine and bladder tissue did have a statistically significant relationship (p = 0.008). Culture of bladder tissue revealed a wider variety of uropathogens.</p><p><strong>Conclusions: </strong>This study proposes that cystoscopy with a bladder biopsy for culture might be a useful adjunctive tool in selected women with refractory symptoms of urine infection.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482939","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Urinary Metabolomic Profile is Minimally Impacted by Common Storage Conditions and Additives.","authors":"Kelly C Weldon, Morgan Panitchpakdi, Andrés Mauricio Caraballo-Rodríguez, Alan J Wolfe, Pieter C Dorrestein, Linda Brubaker, Lindsey A Burnett","doi":"10.1007/s00192-025-06069-2","DOIUrl":"https://doi.org/10.1007/s00192-025-06069-2","url":null,"abstract":"<p><strong>Background: </strong>Metabolomics reflects the molecular communications within biological systems. Urine is a noninvasive biofluid, rich in metabolites that serve as potential biomarkers for human health and disease. The impact of storage conditions and DNA stabilizers for urine samples in metabolomic studies remain unclear.</p><p><strong>Objective: </strong>To evaluate the impact of common storage conditions and the presence of a DNA stabilizer, AssayAssure® (Thermo Scientific), on the metabolite content of voided human urine.</p><p><strong>Methods: </strong>We assessed the urinary metabolite composition under different storage conditions and with the addition of AssayAssure® to determine its effect on metabolomic analysis.</p><p><strong>Results: </strong>Urinary metabolite composition remained consistent across different storage conditions. However, the addition of AssayAssure® significantly altered the metabolic profile due to adduct formation. Despite these alterations, the identification of parent metabolites was not compromised, and biological differences were still distinguishable.</p><p><strong>Conclusion: </strong>These findings suggest that urine biobanked under the tested storage conditions is suitable for metabolomic analysis. The addition of AssayAssure® does not hinder the detection of parent metabolites, although it may affect the overall metabolic profile.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483008","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Results after Early Secondary Repair of Obstetric Anal Sphincter Injury: A Case Series and Literature Review.","authors":"Iben Onsberg Hansen, Ulla Due, Safia Habes, Karoline Daniel Dynesen, Niels Klarskov, Hanna Jangö","doi":"10.1007/s00192-025-06081-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06081-6","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The incidence of obstetric anal sphincter injury (OASI) is 3.6-6% of women with vaginal deliveries. Complications to OASI are common, and secondary repair is needed in 2.6-3%. Traditionally, secondary repair has been postponed until wound healing, but studies have shown that early secondary repair within 21 days can be safely performed.</p><p><strong>Methods: </strong>The aim of this cohort study and literature review was to investigate the long-term outcomes after early secondary repair with focus on anal incontinence, quality of life and impact on sexual function with the use of International Consultation on Incontinence Questionnaire-Bowel (ICIQ-B).</p><p><strong>Results: </strong>A total of 17 patients underwent early secondary repair after OASI within the study period and 11 answered and returned the long-term follow-up questionnaire. Seven had no postoperative complications, nine had infection and two developed recto-vaginal fistulas that needed subsequent surgical treatment. Median follow-up period was 5 years (2.3-5.7). At long-term, ten women (91%) reported fecal urgency, nine (82%) flatal and liquid incontinence, six (55%) problems with soiling and six (55%) unpredictable bowel accidents. Five women (45%) planned daily activities to accommodate their anal incontinence and three (27%) stayed at home because of anal incontinence. Seven women (64%) reported restrictions in their sexual relations due to anal incontinence.</p><p><strong>Conclusions: </strong>In conclusion, early secondary repair of OASI in women with severe wound dehiscence involving the anal sphincter may be necessary. However, this group have a high risk of anal incontinence, negative impact on quality of life, and risk of sexual dysfunction at long-term follow-up.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implantation of Autologous Skeletal Muscle-Derived Cells Combined with Electrical Stimulation in Patients with Stress Urinary Incontinence.","authors":"Achim Rose, Herbert Rübben","doi":"10.1007/s00192-025-06079-0","DOIUrl":"https://doi.org/10.1007/s00192-025-06079-0","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Intrasphincteric injection of autologous skeletal muscle-derived cells (aSMDCs) is a minimally invasive treatment for stress urinary incontinence (SUI). This study investigated two cell counts (high/low dose) for functional urethral sphincter regeneration in combination with electrical stimulation, treatment safety and efficacy, and its potential superiority to duloxetine-placebo or duloxetine.</p><p><strong>Methods: </strong>This phase II, placebo-controlled trial randomised women with SUI to cell implantation (low or high cell number) and to control groups (duloxetine-placebo or duloxetine), each treatment combined with electrical stimulation. The primary efficacy endpoint was the mean reduction of incontinence episode frequency (IEF) at 12 weeks post-treatment compared with baseline. Secondary efficacy parameters included 1-h pad test, visual analogue scale (VAS), Incontinence Quality of Life questionnaire, clinical global impression score and frequency of responders based on IEF. Adverse events were analysed for safety evaluation. Additional follow-up data on IEF and selected secondary efficacy variables were obtained in a sub-population of patients after 12 and 48 months.</p><p><strong>Results: </strong>The mean reduction ± SD in IEF after 12 weeks was: low cells: -16.4 ± 13.3 (61 patients), high cells: -18.5 ± 18.7 (56), placebo: -9.7 ± 13.7 (68), duloxetine -11.2 ± 19.6 (32). Cell treatments were significantly superior over placebo regarding IEF reduction and all secondary endpoints except for VAS. No safety issues were observed following cell implantation. Improvements were sustained over 12 and 48 months, with no difference between low and high cell implantation groups.</p><p><strong>Conclusions: </strong>Therapy for SUI with aSMDCs in combination with electrical stimulation is safe, effective and sustained over at least 48 months.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on \"Whole Exome Sequencing Reveals Candidate Variants in Ion Channel Genes for Pelvic Muscle Dysfunction in Young Females with a Family History\".","authors":"Kristina Allen-Brady","doi":"10.1007/s00192-025-06089-y","DOIUrl":"10.1007/s00192-025-06089-y","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143458043","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}