International Urogynecology Journal最新文献

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Robotic-Assisted Excision of Intravesical Burch Urethropexy Staples and Mesh. 机器人辅助膀胱内Burch输尿管固定钉及网片切除术。
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-13 DOI: 10.1007/s00192-025-06331-7
Courtney K Pfeuti, Brian J Linder
{"title":"Robotic-Assisted Excision of Intravesical Burch Urethropexy Staples and Mesh.","authors":"Courtney K Pfeuti, Brian J Linder","doi":"10.1007/s00192-025-06331-7","DOIUrl":"https://doi.org/10.1007/s00192-025-06331-7","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Use of synthetic mesh material in urogynecology for anti-incontinence surgery risks complications such as vaginal exposure and erosion. Although intravesical erosion is rare, management is complex with limited existing guidance, specifically following retropubic urethral suspension procedures.</p><p><strong>Methods: </strong>This is a 78-year-old female patient referred for management of intravesical mesh and staples. Prior surgical history included a retropubic urethral suspension and laparoscopic Burch urethropexy with Prolene mesh. Following years of persistent urinary symptoms, cystoscopy identified intravesical mesh. Imaging revealed multiple tacking device staples in the retropubic space. Robotic-assisted excision of the intravesical mesh and staples was performed. After identification of the retropubic Burch mesh and dissection to the bladder, an intentional cystotomy was made. Circumferential dissection along the mesh permitted complete excision. The cystotomy was closed in two layers and reinforced with a urachal flap.</p><p><strong>Results: </strong>The patient was discharged on postoperative day one. After two weeks of Foley catheter use, a cystogram showed no extravasation. The patient passed a voiding trial.</p><p><strong>Conclusions: </strong>Robotic-assisted excision of intravesical mesh from a retropubic urethropexy is safe and feasible. Complete surgical excision helps achieve a tension-free closure and prevent recurrence. Surgical techniques demonstrated here may be helpful for managing such cases of intravesical mesh.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145053574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comment on "The Influence of Successful Apical Defect Repair in Laparoscopic Sacrocolpopexy on Quality of Sexual Life". 评论“腹腔镜骶骶固定术根尖缺损修复成功对性生活质量的影响”。
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-11 DOI: 10.1007/s00192-025-06329-1
Ömer Faruk Öz
{"title":"Comment on \"The Influence of Successful Apical Defect Repair in Laparoscopic Sacrocolpopexy on Quality of Sexual Life\".","authors":"Ömer Faruk Öz","doi":"10.1007/s00192-025-06329-1","DOIUrl":"https://doi.org/10.1007/s00192-025-06329-1","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033215","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Translation and Validation of the Persian ICIQ Nocturia and Nocturia Quality of Life. 波斯语ICIQ夜尿和夜尿生活质量的翻译与验证。
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-11 DOI: 10.1007/s00192-025-06306-8
Elham Jahantabi, Golsa Alamdari, Armin Attar, Mahdi Hemmati, Sona Tayebi, Mohammad Amin Tapak, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi
{"title":"Translation and Validation of the Persian ICIQ Nocturia and Nocturia Quality of Life.","authors":"Elham Jahantabi, Golsa Alamdari, Armin Attar, Mahdi Hemmati, Sona Tayebi, Mohammad Amin Tapak, Hanieh Salehi-Pourmehr, Sakineh Hajebrahimi","doi":"10.1007/s00192-025-06306-8","DOIUrl":"https://doi.org/10.1007/s00192-025-06306-8","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>We aimed to translate and validate the International Consultation on Incontinence Questionnaire Nocturia (ICIQ-N) and Nocturia Quality of Life (ICIQ-Nqol) into Persian by assessing the validity and reliability of the translated versions.</p><p><strong>Methods: </strong>The English versions of the ICIQ-N and ICIQ-Nqol were translated into Persian using a forward-backward translation method. Content validity was assessed quantitatively using the Content Validity Index (CVI) and Content Validity Ratio (CVR) by ten urologists. Construct validity was evaluated using exploratory factor analysis (EFA) on data from 208 female patients with at least one lower urinary tract symptom. Internal consistency was determined using Cronbach's alpha, and test-retest reliability was assessed over a 14-day interval using the intraclass correlation coefficient (ICC).</p><p><strong>Result: </strong>The Persian translations demonstrated high content validity, with all items achieving acceptable CVI and CVR values. Exploratory factor analysis revealed a single dominant component for both questionnaires. Cronbach's alpha for the ICIQ-N was 0.888 and for the ICIQ-Nqol was 0.986, indicating excellent internal consistency. Test-retest reliability was also high, with ICC values of 0.869 (95% CI 0.817-0.905) for the ICIQ-N and 0.974 (95% CI 0.968-0.979) for the ICIQ-Nqol.</p><p><strong>Conclusion: </strong>The Persian ICIQ Nocturia and Nocturia Quality of Life were valid and efficiently adapted for use in various settings.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145033208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cross-Sectional Associations of Depressive Symptoms, Anxiety Symptoms, and Emotional Support Seeking with Lower Urinary Tract Symptoms and Bladder Health. 抑郁症状、焦虑症状和情感支持寻求与下尿路症状和膀胱健康的横断面关联
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-10 DOI: 10.1007/s00192-025-06270-3
Sonya S Brady, Deepa R Camenga, Tamera Coyne-Beasley, Chloe Falke, Colleen M Fitzgerald, Bernard L Harlow, Kimberly Kenton, Heather Klusaritz, Cora E Lewis, Dulce P Rodriguez-Ponciano, Kyle D Rudser, Abigail R Smith, Ariana L Smith, Siobhan Sutcliffe, Eliza Wilson-Powers, Shayna D Cunningham
{"title":"Cross-Sectional Associations of Depressive Symptoms, Anxiety Symptoms, and Emotional Support Seeking with Lower Urinary Tract Symptoms and Bladder Health.","authors":"Sonya S Brady, Deepa R Camenga, Tamera Coyne-Beasley, Chloe Falke, Colleen M Fitzgerald, Bernard L Harlow, Kimberly Kenton, Heather Klusaritz, Cora E Lewis, Dulce P Rodriguez-Ponciano, Kyle D Rudser, Abigail R Smith, Ariana L Smith, Siobhan Sutcliffe, Eliza Wilson-Powers, Shayna D Cunningham","doi":"10.1007/s00192-025-06270-3","DOIUrl":"https://doi.org/10.1007/s00192-025-06270-3","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Depressive and anxiety symptoms are known risk factors for lower urinary tract symptoms (LUTS). To inform prevention and treatment strategies, this research examined whether greater emotional support seeking weakened associations of affective symptoms with LUTS and poorer bladder health.</p><p><strong>Methods: </strong>Data were collected from women in the USA who participated in the RISE FOR HEALTH study of bladder health. In this cross-sectional analysis (analytic sample n = 1444), self-reported LUTS, perceived bladder health, and perceived impact of bladder health on five domains of living (social and occupational activities, travel, physical activities, intimacy, and emotions) were separately regressed on depressive symptoms, anxiety symptoms, and emotional support seeking. Interaction tests examined whether emotional support seeking modified associations of affective symptoms with LUTS and bladder health.</p><p><strong>Results: </strong>Report of worse depressive symptoms, worse anxiety symptoms, and lower levels of engagement in emotional support seeking were associated with more frequent LUTS, poorer perceived bladder health, and lower perceived positive impact of bladder health on each domain of living. Emotional support seeking was not associated with LUTS and bladder health outcomes when adjusting for affective symptoms, and did not modify associations of affective symptoms with LUTS and bladder health outcomes.</p><p><strong>Conclusions: </strong>Intervention research to prevent LUTS and promote bladder health can test strategies that include screening and providing timely treatment of affective symptoms. Health care providers treating women for LUTS can screen for affective symptoms and make referrals to ensure that both the physical health and the mental health needs of patients are being met.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145029716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Turkish Translation and Cross-Cultural Adaptation of the Pelvic Floor Dysfunction-SENTINEL Screening Tool: A Methodological Study. 骨盆底功能障碍的土耳其语翻译和跨文化适应-哨兵筛查工具:一项方法学研究。
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-09 DOI: 10.1007/s00192-025-06311-x
Seyda Toprak Celenay, Elif Sena Dusgun, Mesut Arslan, Derya Ozer Kaya
{"title":"Turkish Translation and Cross-Cultural Adaptation of the Pelvic Floor Dysfunction-SENTINEL Screening Tool: A Methodological Study.","authors":"Seyda Toprak Celenay, Elif Sena Dusgun, Mesut Arslan, Derya Ozer Kaya","doi":"10.1007/s00192-025-06311-x","DOIUrl":"https://doi.org/10.1007/s00192-025-06311-x","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>To translate and perform cultural adaptation of the Pelvic Floor Dysfunction-SENTINEL (PFD-SENTINEL) screening tool into Turkish and to establish its reliability and validity for female athletes.</p><p><strong>Methods: </strong>The study included 200 female athletes (mean age 22 ± 4 years). The translation of the PFD-SENTINEL, which comprised the symptoms related to PFD and item sections related to general risk factors and sports-related risk factors, was performed in accordance with international recommendations. The severity of PFD symptoms was assessed with the Pelvic Floor Distress Inventory-20 (PFDI-20). Psychometric analyses consisted of assessing the following: internal consistency reliability using the Kuder-Richardson-20 (KR-20) coefficient, construct validity using confirmatory factor analysis, and criterion validity.</p><p><strong>Results: </strong>The reliability was acceptable for the PFD-SENTINEL items assessed using the KR-20, at 0.581, indicating moderate internal consistency. All fit indices except standardized root mean square residual indicated a perfect fit for the final models. Criterion validity was supported by positive correlations between the PFD-SENTINEL symptom score and the PFDI-20 score (r = 0.724, p < 0.001) and between the PFD-SENTINEL item score and the PFIQ-20 scores (r = 0.334; p < 0.001).</p><p><strong>Conclusions: </strong>The Turkish version of the PFD-SENTINEL is a reliable and valid instrument to screen for PFD in female athletes.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023313","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Randomized Comparison of Video Demonstration, Simulation-Based Training, and Combination Using Silicone-Latex Simulation for Anal Sphincter Injury Repair in Obstetrics and Gynecology Residents. 妇产科住院医师肛门括约肌损伤修复中视频演示、模拟训练及硅胶-乳胶模拟联合应用的随机比较
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-08 DOI: 10.1007/s00192-025-06299-4
Riska Wahyuningtyas, Eighty Mardiyan Kurniawati, Gatut Hardianto, Hari Paraton, Tri Hastono Setyo Hadi, Djoko Kuswanto
{"title":"Randomized Comparison of Video Demonstration, Simulation-Based Training, and Combination Using Silicone-Latex Simulation for Anal Sphincter Injury Repair in Obstetrics and Gynecology Residents.","authors":"Riska Wahyuningtyas, Eighty Mardiyan Kurniawati, Gatut Hardianto, Hari Paraton, Tri Hastono Setyo Hadi, Djoko Kuswanto","doi":"10.1007/s00192-025-06299-4","DOIUrl":"https://doi.org/10.1007/s00192-025-06299-4","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Our aim was to compare residents' skill for anal sphincter injury repair in a silicone-latex simulation anal sphincter injury model after video demonstration, simulation-based training, and a combination of both.</p><p><strong>Methods: </strong>We randomized obstetrics and gynecology residents to video demonstration by an expert (group 1), simulation-based training (group 2) and a combination training model (group 3) using a validated silicone-latex simulation anal sphincter injury model. We tested the anal sphincter injury repair skills of the residents using the global rating scale (GRS) and the objective structured assessment of technical skills (OSATS) scoring system. We assessed the validity of the GRS and OSATS scoring system in Bahasa using this anal sphincter injury model.</p><p><strong>Results: </strong>Thirty-three residents were randomized into the three groups. Group 3 had the largest different in GRS scores (9.82 95% CI (8.45-11.19)). Group 2 (9.45 95% CI (7.85-11.05)) followed and the lowest different GRS score was in group 1 (7.18 95% CI (5.95-8.41)). There was a significant difference amongst the three group (p = 0.018). The highest OSATS score difference was in group 3 (8.91 95% CI (7.49-10.33)), followed by group 2 (6.82 95% CI (5.55-8.09)), and the lowest score difference was in group 1 (5.45 95% CI (3.39-7.52)). There was a significant difference amongst the three groups (p = 0.007).</p><p><strong>Conclusions: </strong>Combination training is the most superior training for improving anal sphincter injury repair in a simulation model.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Letter to the Editor: "Bone-Targeted High-Intensity Training Does Not Reduce Quality of Life Related to Pelvic Floor Dysfunction: The MEDEX-OP Randomized Controlled Trial". 致编辑的信:“针对骨骼的高强度训练不会降低与盆底功能障碍相关的生活质量:MEDEX-OP随机对照试验”。
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-08 DOI: 10.1007/s00192-025-06320-w
Parth Aphale, Shashank Dokania, Himanshu Shekhar
{"title":"Letter to the Editor: \"Bone-Targeted High-Intensity Training Does Not Reduce Quality of Life Related to Pelvic Floor Dysfunction: The MEDEX-OP Randomized Controlled Trial\".","authors":"Parth Aphale, Shashank Dokania, Himanshu Shekhar","doi":"10.1007/s00192-025-06320-w","DOIUrl":"https://doi.org/10.1007/s00192-025-06320-w","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145023263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How to Approach Female Sexual Dysfunction in a Urogynecology Practice. 如何处理女性性功能障碍在泌尿妇科实践。
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-08 DOI: 10.1007/s00192-025-06254-3
Danielle D Antosh, Mallika Anand, Uchenna Ossai, Sophie Bergeron
{"title":"How to Approach Female Sexual Dysfunction in a Urogynecology Practice.","authors":"Danielle D Antosh, Mallika Anand, Uchenna Ossai, Sophie Bergeron","doi":"10.1007/s00192-025-06254-3","DOIUrl":"https://doi.org/10.1007/s00192-025-06254-3","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Sexual dysfunction is prevalent among women with pelvic floor disorders presenting to urogynecologists.</p><p><strong>Methods: </strong>This review summarizes a workshop held at the 2024 annual International Urogynecology Association meeting and covers the treatment of common sexual dysfunction treatments in a urogynecology practice, how pelvic floor surgery can affect sexual health, and when to refer to a pelvic floor physical therapist or sexual health therapist.</p><p><strong>Results: </strong>For patients suffering from female sexual interest/arousal disorder and orgasmic disorder, medical management, pelvic floor physical therapy, sex therapy, and mechanical devices can be utilized. For women requiring surgery, sexual function either improves or remains unchanged after prolapse surgery and midurethral sling surgery. Dyspareunia rates are lower after all prolapse surgery types compared with preoperative dyspareunia. De novo dyspareunia ranged from 0 to 9% after prolapse repairs.</p><p><strong>Conclusion: </strong>Management of pelvic floor disorders can have a positive impact on sexual function. Many treatments are multidisciplinary and may require referral to a pelvic floor physical therapist or sex therapist.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complication Rates are Low for Women Aged 70 and Older Undergoing Sacrocolpopexy. 70岁及以上妇女骶髋固定术并发症发生率低。
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-08 DOI: 10.1007/s00192-025-06277-w
Tien C Nguyen, Halina Zyczynski, Mary F Ackenbom, Stephanie W Zuo
{"title":"Complication Rates are Low for Women Aged 70 and Older Undergoing Sacrocolpopexy.","authors":"Tien C Nguyen, Halina Zyczynski, Mary F Ackenbom, Stephanie W Zuo","doi":"10.1007/s00192-025-06277-w","DOIUrl":"10.1007/s00192-025-06277-w","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Aging may place patients at greater risk for adverse perioperative outcomes. We hypothesized that women undergoing minimally invasive (MIS) sacrocolpopexy aged ≥ 70 years are more likely to experience adverse events (AE) within 8 weeks of surgery.</p><p><strong>Methods: </strong>We performed a secondary analysis of a retrospective study on perioperative adverse events in women ≥ 61 years old undergoing prolapse surgery at a single academic center from January 2016 to May 2023. Only women undergoing MIS sacrocolpopexy were included. The primary outcome was a composite 8-week AE outcome. Secondary outcomes included prolapse recurrence and mesh complication. Variables were compared between the groups using t-test (or Mann-Whitney U) and chi-square (or Fisher's exact) analyses. Multivariable logistic regression was performed, controlling for variables with p < 0.05 on univariate analysis.</p><p><strong>Results: </strong>Of the 709 women who underwent MIS sacrocolpopexy, 29.9% (n = 212) were aged ≥ 70 years. Age ≥ 70 was not significantly associated with 8-week perioperative AEs, nor was it associated with prolapse recurrence or mesh complication. The composite AE outcome was not associated with age ≥ 70 on multivariable analysis, controlling for CCI score, robotic approach, and concomitant hysterectomy (adjusted odds ratio (aOR) 0.64, 95% confidence interval (CI) [0.38-1.10]). Women aged ≥ 70 years had a 73% lesser adjusted odds of surgical site infections on multivariable analysis (95% CI [0.08-0.93]).</p><p><strong>Conclusions: </strong>Age ≥ 70 years is not associated with perioperative AEs, prolapse recurrence, or mesh complication. These findings highlight the safety profile of this surgical approach in older women, an important consideration for urogynecologic surgeons caring for an aging population.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Randomized Controlled Trial of Platelet-Rich Plasma Combined with Fractional CO2 Laser Therapy for Mild and Moderate Stress Urinary Incontinence in Women. 富血小板血浆联合部分CO2激光治疗女性轻中度应激性尿失禁的随机对照试验
IF 1.8 3区 医学
International Urogynecology Journal Pub Date : 2025-09-08 DOI: 10.1007/s00192-025-06292-x
Mingjing Lu, Weijiao Liu, Yuchan Wu, Kaixian Deng
{"title":"A Randomized Controlled Trial of Platelet-Rich Plasma Combined with Fractional CO<sub>2</sub> Laser Therapy for Mild and Moderate Stress Urinary Incontinence in Women.","authors":"Mingjing Lu, Weijiao Liu, Yuchan Wu, Kaixian Deng","doi":"10.1007/s00192-025-06292-x","DOIUrl":"https://doi.org/10.1007/s00192-025-06292-x","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This study aimed to evaluate the effectiveness of platelet-rich plasma (PRP) combined with fractional CO<sub>2</sub> laser therapy in women diagnosed with mild or moderate stress urinary incontinence (SUI).</p><p><strong>Methods: </strong>In this single-center, single-blinded, randomized controlled trial, 69 women diagnosed with mild or moderate SUI were randomly assigned to receive fractional CO<sub>2</sub> laser therapy, PRP injections, or a combination of both treatments (n = 23 per group). Each participant underwent three treatment sessions at 30-day intervals. Outcomes were assessed using the International Consultation on Incontinence Questionnaire-Short Form (ICI-Q-SF), the Incontinence Quality of Life (I-QOL) questionnaire, and a 1-h pad test at baseline and at 1, 3, and 6 months post-treatment. Generalized estimating equations (GEE) were used to analyze repeated measures across groups.</p><p><strong>Results: </strong>No statistically significant differences in baseline characteristics were observed among the groups (P > 0.05). All groups demonstrated significant post-treatment improvements in ICI-Q-SF scores, I-QOL scores, and 1-h pad weights (P < 0.05). Compared to the fractional CO<sub>2</sub> laser group, the PRP group showed no significant advantage, whereas the combined group exhibited significantly greater improvements at all time points: greater reductions in ICI-Q-SF scores (β = -1.09, -1.30, -1.39; all P < 0.001), higher I-QOL scores (β = 4.39, 4.61, 5.04; all P < 0.001), and greater decreases in pad weights (β = -1.22, -1.48, -1.78; all P < 0.05).</p><p><strong>Conclusions: </strong>Combined PRP and fractional CO<sub>2</sub> laser therapy significantly improves urinary incontinence symptoms and quality of life compared to either treatment alone, offering a potentially more effective therapeutic option for women diagnosed with mild or moderate SUI.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145015399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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