The Safety of Robot-Assisted Sacrocolpopexy in Pelvic Organ Prolapse Treatment: Systematic Review and Meta-Analysis.

IF 1.8 3区 医学 Q3 OBSTETRICS & GYNECOLOGY
Bagrat Grigoryan, George Kasyan, Roman Shapovalenko, Alexander Popov, Dmitry Pushkar
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Abstract

Introduction and hypothesis: The aim of this study is to evaluate the safety of robot-assisted sacrocolpopexy (RSP) compared with other approaches of sacrocolpopexy and vaginal surgery in pelvic organ prolapse (POP).

Methods: The search was performed on studies published prior to May 2024. The inclusion criteria were randomized and nonrandomized trials involving adult women with POP. Exclusion criteria comprised other forms of intervention treatments and articles lacking comparative analyses. This study adhered to the Population, Intervention, Comparison, and Outcome framework, the Preferred Reporting Items for Systematic Reviews and Meta-Analyses 2020 checklist, and was registered in the Prospective Register of Systematic Reviews.

Results: The systematic review included 36 studies, whereas the meta-analysis included 30 studies. RSP demonstrated superior outcomes compared with laparoscopic (LSP), abdominal (ASP), and vaginal surgery (VS) approaches, with fewer perioperative complications (p < 0.00001 for RSP vs ASP; p = 0.01 for RSP vs VS), reduced blood loss (total p < 0.00001 for RSP vs LSP, ASP, and VS), and shorter hospital stays (p = 0.003 for RSP vs LSP; p = 0.27 for RSP vs VS). Additionally, RSP had fewer surgical conversions than LSP (p = 0.01). However, LSP and VS showed significantly shorter operation times than RSP (p < 0.00001).

Conclusions: Robot-assisted sacrocolpopexy may offer advantages in reducing blood loss compared with VS and shortening hospital stays compared with LSP. Sensitivity analyses, however, revealed no significant differences in perioperative complications or blood loss compared with LSP and ASP. Further high-quality randomized studies are necessary to confirm the safety and efficacy of RSP.

机器人辅助骶髋固定术治疗盆腔器官脱垂的安全性:系统回顾和荟萃分析。
前言与假设:本研究的目的是评估机器人辅助骶colpop固定术(RSP)与其他骶colpop固定术和阴道手术治疗盆腔器官脱垂(POP)的安全性。方法:检索2024年5月之前发表的研究。纳入标准为涉及成年女性POP的随机和非随机试验。排除标准包括其他形式的干预治疗和缺乏比较分析的文章。本研究遵循人口、干预、比较和结果框架、系统评价和荟萃分析2020清单的首选报告项目,并在前瞻性系统评价登记册中注册。结果:系统评价纳入36项研究,而荟萃分析纳入30项研究。与腹腔镜手术(LSP)、腹腔手术(ASP)和阴道手术(VS)相比,RSP表现出更好的结果,围手术期并发症更少(p)。结论:与腹腔镜手术相比,机器人辅助骶colpop固定术可能在减少失血量和缩短住院时间方面具有优势。然而,敏感性分析显示,与LSP和ASP相比,围手术期并发症和出血量无显著差异。需要进一步的高质量随机研究来证实RSP的安全性和有效性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.80
自引率
22.20%
发文量
406
审稿时长
3-6 weeks
期刊介绍: The International Urogynecology Journal is the official journal of the International Urogynecological Association (IUGA).The International Urogynecology Journal has evolved in response to a perceived need amongst the clinicians, scientists, and researchers active in the field of urogynecology and pelvic floor disorders. Gynecologists, urologists, physiotherapists, nurses and basic scientists require regular means of communication within this field of pelvic floor dysfunction to express new ideas and research, and to review clinical practice in the diagnosis and treatment of women with disorders of the pelvic floor. This Journal has adopted the peer review process for all original contributions and will maintain high standards with regard to the research published therein. The clinical approach to urogynecology and pelvic floor disorders will be emphasized with each issue containing clinically relevant material that will be immediately applicable for clinical medicine. This publication covers all aspects of the field in an interdisciplinary fashion
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