International Urogynecology Journal最新文献

Outcome of Laparoscopic Versus Vaginal High Uterosacral Ligament Vault Suspension at the Time of Hysterectomy.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-07 DOI: 10.1007/s00192-024-06033-6

Sascha Vereeck, James Alexander, Michael Carey, Anna Rosamilia

{"title":"Outcome of Laparoscopic Versus Vaginal High Uterosacral Ligament Vault Suspension at the Time of Hysterectomy.","authors":"Sascha Vereeck, James Alexander, Michael Carey, Anna Rosamilia","doi":"10.1007/s00192-024-06033-6","DOIUrl":"https://doi.org/10.1007/s00192-024-06033-6","url":null,"abstract":"Introduction and hypothesis: High uterosacral ligament suspension (HUSLS) can be used to treat apical pelvic organ prolapse (POP). This can be performed both vaginally and laparoscopically. Data comparing the two suspension procedures remain limited. The aim of this study is to compare the effectiveness and safety of vaginal HUSLS and laparoscopic HUSLS at the time of hysterectomy.Methods: This is a retrospective cohort study of women who underwent hysterectomy between 2019 and 2021 at a tertiary urogynaecology unit. Either vaginal or laparoscopic hysterectomy was performed, followed by vaginal or laparoscopic HUSLS respectively. Women were followed up at 6 weeks, and at 6 and 12 months postoperatively. The primary outcome was symptomatic recurrence of vaginal bulge symptoms. Secondary outcomes were anatomical recurrence, re-treatment and safety.Results: A total of 111 women met the inclusion criteria. Twelve were excluded, leaving 99 for analysis. HUSLS was performed vaginally in 47 and laparoscopically in 52 women. There was no significant difference in demographics between the groups. At 12 months, 92% in the vaginal group and 48% of the laparoscopic group reported no symptoms of prolapse, 67% vs 36% had no anatomical recurrence and 0% vs 34% had re-treatment respectively. Logistic regression (adjusting for age, BMI, menopausal status, preoperative stage apical prolapse, procedure type) demonstrated that the laparoscopic route was the only variable associated with recurrent prolapse at or beyond the hymen and symptomatic prolapse at 12 months.Conclusions: Symptomatic and anatomical recurrent POP was associated with this technique of laparoscopic HUSLS. Further research should consider prospective evaluation of these or modified techniques.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Use of Transperineal Ultrasonography to Compare Relevant Factors for Postpartum Urinary Incontinence Related to Different Modes of Delivery.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-07 DOI: 10.1007/s00192-025-06073-6

Qing Feng, Kun Wang, Wan T Xu, Jian M Huang, Hui H Yang, Yu He

{"title":"The Use of Transperineal Ultrasonography to Compare Relevant Factors for Postpartum Urinary Incontinence Related to Different Modes of Delivery.","authors":"Qing Feng, Kun Wang, Wan T Xu, Jian M Huang, Hui H Yang, Yu He","doi":"10.1007/s00192-025-06073-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06073-6","url":null,"abstract":"Introduction and hypothesis: Studies concerning the similarities and differences in relevant factors for PPUI in puerpera with delivery modes are scarce. This study aimed to investigate relevant factors for PPUI among primiparas grouped by different delivery modes using transperineal ultrasonography.Methods: This is a retrospective cohort study. Seven hundred thirty-eight primiparas were included and their clinical and ultrasonographic data were collected. First, they were divided into the UI group (n = 233) and non-UI group (n = 505). Then all participants were redivided into the vaginal delivery without episiotomy group (n = 271), the vaginal delivery with episiotomy group (n = 158), and the cesarean section group (n = 309). Independent relevant factors of PPUI were analyzed with the delivery mode as one of the variables and as a grouping factor, respectively.Results: BMI, delivery modes, vertical distances between the location of bladder neck and the reference line of the inferior symphyseal margin at rest (BSDr), and [bladder neck descent (BND)]/BSDr were independently associated with PPUI in the overall study population. Among the participants grouped by delivery modes, the maternal BMI, BSDr, and retrovesical angle during Valsalva maneuver (RVAv) were independently associated with PPUI in the vaginal delivery without episiotomy group. BND/BSDr was the independent relevant factor of PPUI in the cesarean section group. In the vaginal delivery with episiotomy group, no factors were independently associated with PPUI.Conclusions: The independent relevant factors for PPUI in primiparas varied with delivery modes. Sonographic measurements were independently associated with PPUI related to different delivery modes, acting as differential markers to identify PPUI.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Influence of Powerlifting and Weightlifting on Female Pelvic Floor Dysfunction: Systematic Literature Review.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-07 DOI: 10.1007/s00192-025-06059-4

Andressa Soares Castro Alves, Maita Poli de Araújo, Gláucia Miranda Varella Pereira, Luiz Gustavo Oliveira Brito, Cássia Raquel Teatin Juliato

{"title":"Influence of Powerlifting and Weightlifting on Female Pelvic Floor Dysfunction: Systematic Literature Review.","authors":"Andressa Soares Castro Alves, Maita Poli de Araújo, Gláucia Miranda Varella Pereira, Luiz Gustavo Oliveira Brito, Cássia Raquel Teatin Juliato","doi":"10.1007/s00192-025-06059-4","DOIUrl":"https://doi.org/10.1007/s00192-025-06059-4","url":null,"abstract":"Introduction and hypothesis: The participation of women in sports such as powerlifting and weightlifting has grown over the years, and there is no consensus on the role of exercises in pelvic floor disorders (PFDs). We aimed to identify and summarize the current evidence on the impact of powerlifting and weightlifting on PFDs.Methods: A systematic literature search was conducted on databases with no language restriction, from inception to 20 January 2024. We included observational studies or randomized controlled trials investigating female athletes in powerlifting or weightlifting providing information regarding the impact of these sports on pelvic floor structures. Studies on CrossFit trainers, nonfemale athletes, age <18, and congress abstracts were excluded. Two researchers independently performed the data extraction and quality assessment. The risk of bias was assessed using the Risk Of Bias In Non-randomized Studies-of Interventions. The main outcomes were the prevalence of PFDs in women practicing powerlifting or weightlifting, the factors associated with PFDs, and exercise related to urinary loss.Results: Of the 221 articles found, 5 studies with 1,809 participants were included in the qualitative synthesis. The prevalence of urinary incontinence (UI) in powerlifters ranged from 41.0% to 48.8% and in weightlifters from 36.6% to 54.1%. The main associated factors were age, parity, and body mass index. Deadlift was the exercise most commonly associated with UI (42.5%), followed by squats (36.3%). High loads and repetitions, along with competitions, were associated with UI.Conclusion: This systematic review reveals a clear connection between PFD, particularly UI, and the engagement of women in powerlifting and weightlifting.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of Single-Incision Sling Placement on Female Sexual Function in Women with Stress Urinary Incontinence.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-06 DOI: 10.1007/s00192-025-06058-5

Marie Van Isacker, Frank Van der Aa

{"title":"Impact of Single-Incision Sling Placement on Female Sexual Function in Women with Stress Urinary Incontinence.","authors":"Marie Van Isacker, Frank Van der Aa","doi":"10.1007/s00192-025-06058-5","DOIUrl":"https://doi.org/10.1007/s00192-025-06058-5","url":null,"abstract":"Introduction and hypothesis: Stress urinary incontinence (SUI) is a common condition among women of childbearing age, often requiring surgical intervention. The midurethral sling (MUS), including first-generation tension-free vaginal tapes (TVT) and second-generation transobturator tapes (TOT, TVT-O), has long been the standard treatment. However, both approaches have associated risks, prompting the development of single-incision slings (SIS) as a third option. SIS have proven their efficacy in SUI treatment, but the impact of these slings on female sexual function specifically remains underexplored.Methods: A literature search was conducted using PubMed using the keywords \"stress urinary incontinence,\" \"midurethral slings,\" \"single-incision slings,\" \"female sexual function,\" and \"dyspareunia.\"Results: The reviewed studies demonstrated that SIS generally maintain or improve sexual function postoperatively, but with varying impact on specific aspects of sexual function. While coital urinary incontinence often improved or resolved, new or worsened dyspareunia was reported in a significant number of patients.Conclusion: SIS placement for SUI generally preserves or enhances sexual function, though individual aspects, such as dyspareunia, may worsen for some patients. Given that an important goal of SUI treatment is to improve quality of life, it is crucial to identify preoperative factors that will identify patients at risk of developing dyspareunia after surgery or are more likely to experience an improvement in sexual function. Further research is needed to better understand these predictors and optimize surgical outcomes for women undergoing SUI treatment with SIS.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143255660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Response to Letter to the Editor: "Type III Collagen RNA Level Expression in Pelvic Organ Prolapse: A Systematic Review and Meta-Analysis".

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-06 DOI: 10.1007/s00192-025-06074-5

Akbar Novan Dwi Saputra, Dicky Moch Rizal, Nandia Septiyorini, Muhammad Nurhadi Rahman

引用次数: 0

Rate of Urine Culture Contamination with Different Methods of Urine Specimen Collection.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-05 DOI: 10.1007/s00192-025-06068-3

Sarah Ashmore, Jinxuan Shi, Tara Samsel, Margaret G Mueller, Juraj Letko, Kimberly Kenton

{"title":"Rate of Urine Culture Contamination with Different Methods of Urine Specimen Collection.","authors":"Sarah Ashmore, Jinxuan Shi, Tara Samsel, Margaret G Mueller, Juraj Letko, Kimberly Kenton","doi":"10.1007/s00192-025-06068-3","DOIUrl":"https://doi.org/10.1007/s00192-025-06068-3","url":null,"abstract":"Background: Midstream urine (MSU) samples are commonly collected at the time of patient evaluation despite known high rates of contamination.Objective: The primary objective of this study was to evaluate the rate of mixed flora results in urine specimens obtained by MSU compared to straight catheterization urine (SCU).Study design: This was a quality improvement project evaluating urine culture results of women who provided either an MSU or SCU sample for analysis. Adult women seen within urogynecology clinics at a tertiary care center between April and August 2023 who had urine cultures performed for any indication were included. Mixed flora was defined as the presence of ≥ 2 non-uropathogens or 1 uropathogen in low quantity (at least 10 times fewer) compared to the concentration of nonsignificant organisms.Results: Three hundred forty women provided a urine specimen during the study period. SCU collection was performed for 171 (50.3%) women while 169 (49.7%) provided an MSU sample. Overall, 18.8% of urine cultures were reported as mixed flora (33.1% in MSU and 4.7% in SCU, p < 0.001). Mixed flora was more common with MSU specimens (87.5%, p < 0.001) and associated with a higher BMI compared to positive or negative cultures (mixed flora 29.8 kg/m2 ± 16.3, positive or negative cultures 27.8 kg/m2 ± 7.0, p = 0.04). MSU samples had increased odds of urine contamination compared to SCU collection (7.40 aOR, 95% CI 3.01-18.24).Conclusion: The prevalence of mixed flora was reduced significantly when SCU samples were obtained. Clinicians should consider performing SCU collection when a urine specimen is required for patient evaluation.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pelvic Floor Dysfunction and Associated Factors in Women with Systemic Autoimmune Rheumatic Diseases: A Cross-Sectional Study.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-04 DOI: 10.1007/s00192-025-06071-8

Cristiano Carvalho, Ana Paula Rodrigues Rocha, Gabriel Bernardi Dos Santos, Júlia Barbosa Guimarães, Mariana Nobrega Amorim, Ana Carolina Sartorato Beleza, Daiana Priscila Rodrigues-de-Souza, Paula Regina Mendes da Silva Serrão, Tatiana de Oliveira Sato

{"title":"Pelvic Floor Dysfunction and Associated Factors in Women with Systemic Autoimmune Rheumatic Diseases: A Cross-Sectional Study.","authors":"Cristiano Carvalho, Ana Paula Rodrigues Rocha, Gabriel Bernardi Dos Santos, Júlia Barbosa Guimarães, Mariana Nobrega Amorim, Ana Carolina Sartorato Beleza, Daiana Priscila Rodrigues-de-Souza, Paula Regina Mendes da Silva Serrão, Tatiana de Oliveira Sato","doi":"10.1007/s00192-025-06071-8","DOIUrl":"https://doi.org/10.1007/s00192-025-06071-8","url":null,"abstract":"Introduction and hypothesis: Systemic autoimmune rheumatic diseases (SARDs) cause musculoskeletal disorders and are associated with various issues that affect the quality of life. Since the musculoskeletal system is affected, the pelvic floor muscles can also be impacted, leading to possible pelvic floor dysfunctions (PFDs). Thus, the purpose of this study was to investigate the presence of PFDs, such as urinary incontinence (UI), anal incontinence (AI), genital-pelvic pain/penetration disorder (GPPPD), and pelvic organ prolapse (POP) symptoms in women with SARDs compared to a control group composed of women without SARDs; and investigate the association between SARDs and PFDs.Methods: An online cross-sectional survey was carried out. Using a web-based questionnaire, data on demographic and anthropometric features, PFD (UI, nocturia, AI, GPPPD, and POP), and obstetric history were gathered. For quantitative variables, the Mann-Whitney U test was used, and for categorical variables, the chi-squared test was used for comparison between groups. The association between SARDs and PFD was investigated using logistic regression analysis.Results: The questionnaire was completed by 326 women (224 with SARDs and 102 healthy controls). Women with SARDs reported significantly more symptoms of PFD, UI, nocturia, AI (flatus and fecal incontinence), POP, and GPPPD than healthy controls. SARDs were associated with PFD, flatus incontinence, fecal incontinence, dyspareunia, and vaginismus.Conclusions: PFD was much more common in women with SARDs than in healthy women. Women with SARDs were 1.8 to 5.2 times more likely than the control group to report PFD symptoms than women without SARDs.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Symptomatic Pelvic Floor Disorders in Community-Dwelling Women in Central Gondar Zone, Northwest Ethiopia.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-04 DOI: 10.1007/s00192-025-06053-w

Zelalem Ayichew Workineh, Zelalem Mengistu Gashaw, Tamiru Minwuye Andargie, Tibeb Zena Debele, Solomon Gedlu Nigatu, Wagaye Fentahun Chanie, Tadesse Belayneh Melkie

{"title":"Symptomatic Pelvic Floor Disorders in Community-Dwelling Women in Central Gondar Zone, Northwest Ethiopia.","authors":"Zelalem Ayichew Workineh, Zelalem Mengistu Gashaw, Tamiru Minwuye Andargie, Tibeb Zena Debele, Solomon Gedlu Nigatu, Wagaye Fentahun Chanie, Tadesse Belayneh Melkie","doi":"10.1007/s00192-025-06053-w","DOIUrl":"https://doi.org/10.1007/s00192-025-06053-w","url":null,"abstract":"Introduction and hypothesis: This study was aimed at assessing the prevalence and factors contributing to pelvic floor disorder (PFD) symptoms.Methods: A community-based cross-sectional study was employed among 737 women in the central Gondar Zone of Northwest Ethiopia from September to December 2022. Participants were selected using a multi-stage cluster sampling. The Amharic version of the Pelvic Floor Disorder Inventory 20 (PFDI-20) tool was employed to evaluate the occurrence of PFDs. Bi-variable and multivariable logistic regression models were fitted to identify associated factors of PFDs.Results: The prevalence of at least one form of PFD was 26.9% (95% CI 23.3 to 30.0%). Pelvic organ prolapse symptoms, urinary incontinence, and fecal incontinence were reported at rates of 19.9%, 19.7%, and 12.8% respectively. Factors associated with PFDs included increasing age (AOR = 3.61, 95% CI 1.01 to 6.91), residing in a rural area (AOR = 2.12, 95% CI 1.63 to 3.66), a history of difficult labor (AOR = 1.83, 95% CI 1.26 to 2.66), multiple vaginal deliveries (AOR = 2.41, 95% CI 2.18 to 3.92), home delivery (AOR = 1.29, 95% CI 1.86 to 2.93), and being postmenopausal (AOR = 1.62, 95% CI 1.55 to 2.89).Conclusions: Currently, more than 25% of women are experiencing distressing symptoms associated with PFDs. Contributing factors include older age, rural residence, having multiple vaginal deliveries, and postmenopausal status. Therefore, it is essential to focus on the early identification of PFD symptoms, raise awareness within the community and among women regarding the connections between advanced age, menopause, and multiparity, and advocate for family planning initiatives.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Interplay Between Chronic Pelvic Pain and Pelvic Organ Prolapse. 慢性骨盆疼痛与骨盆器官脱垂之间的相互作用

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-04 DOI: 10.1007/s00192-024-06040-7

Maria Thereza Albuquerque Barbosa Cabral Micussi, Vatche Arakel Minassian, Rachan Mohamed Ghandour, Jeannine Marie Miranne

{"title":"The Interplay Between Chronic Pelvic Pain and Pelvic Organ Prolapse.","authors":"Maria Thereza Albuquerque Barbosa Cabral Micussi, Vatche Arakel Minassian, Rachan Mohamed Ghandour, Jeannine Marie Miranne","doi":"10.1007/s00192-024-06040-7","DOIUrl":"https://doi.org/10.1007/s00192-024-06040-7","url":null,"abstract":"Introduction and hypothesis: Chronic pelvic pain (CPP) affects approximately 26% of the world's female population and has various proposed etiologies. This manuscript aims to review concepts related to pelvic organ prolapse (POP) and CPP, encompassing its etiology, risk factors, clinical findings, and pain management.Methods: A narrative review was performed using MeSH terms and text words on PubMed, and the Cochrane Database of Systematic Reviews through May 2024. A total of 33 references were used to address the questions posed in this review.Results: Specific risk factors for CPP associated with POP include pain antedating POP onset, POP surgery duration, and extent of soft tissue trauma. Studies indicate that uterosacral ligament repair performed during surgical interventions for POP correction has alleviated CPP symptoms whether performed vaginally or laparoscopically. Women with preexisting CPP or central sensitization syndrome (CSS) undergoing pelvic reconstructive surgery for POP may experience less favorable postoperative outcomes compared to those without preexisting pain conditions. These outcomes include lower patient satisfaction, less resolution of discomfort, and poorer improvement in urinary symptoms.Conclusions: On the basis of current evidence, surgeries for POP correction, especially those involving the uterosacral ligament, have shown a positive impact on reducing pelvic pain. However, untreated CPP is associated with lower satisfaction and less improvement in outcomes after POP surgery regarding pelvic symptoms and quality of life. Screening for and treating CPP conditions prior to POP surgery should be prioritized. Pain management of CPP should be addressed preoperatively, perioperatively, and postoperatively.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Validation of Risk Assessment Model for Pelvic Organ Prolapse Based on A Retrospective Study with Machine Learning Algorithms.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-03 DOI: 10.1007/s00192-025-06046-9

Ling Mei, Linbo Gao, Tao Wang, Dong Yang, Weixing Chen, Xiaoyu Niu

{"title":"Development and Validation of Risk Assessment Model for Pelvic Organ Prolapse Based on A Retrospective Study with Machine Learning Algorithms.","authors":"Ling Mei, Linbo Gao, Tao Wang, Dong Yang, Weixing Chen, Xiaoyu Niu","doi":"10.1007/s00192-025-06046-9","DOIUrl":"https://doi.org/10.1007/s00192-025-06046-9","url":null,"abstract":"Introduction and hypothesis: We aimed to develop and validate a clinically applicable risk assessment model for identifying women at a high risk of pelvic organ prolapse (POP) based on a retrospective practice.Methods: This study enrolled patients with and without POP between January 2019 and December 2021. Clinical data were collected and machine learning models were applied, such as multilayer perceptron, logistic regression, random forest (RF), light gradient boosting machine and extreme gradient boosting. Two datasets were constructed, one comprising all variables and the other excluding physical examination variables. Two versions of the machine learning model were developed. One was for professional doctors, and the other was for community-health providers. The area under the curve (AUC) and its confidence interval (CI), accuracy, F1 score, sensitivity, and specificity were calculated to evaluate the model's performance. The Shapley Additive Explanations method was used to visualize and interpret the model output.Results: A total of 16,416 women were recruited, with 8,314 and 8,102 in the POP and non-POP groups respectively. Eighty-seven variables were recorded. Among all candidate models, the RF model with 13 variables showed the best performance, with an AUC of 0.806 (95% CI 0.793-0.817), accuracy of 0.723, F1 of 0.731, sensitivity of 0.742, and specificity of 0.703. Excluding the physical examination variables, the RF model with 11 variables showed an AUC, accuracy, F1 score, sensitivity, and specificity of 0.716, 0.652, 0.688, 0.757, and 0.545 respectively.Conclusions: We constructed a clinically applicable risk warning system that will help clinicians to identify women at a high risk of POP.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0