International Urogynecology Journal最新文献

{"title":"Turkish Adaptation of Four Questionnaires for Patients with Overactive Bladder: The Overactive Bladder Questionnaire (OAB-Q), Urgency Questionnaire (UQ), Primary OAB Symptom Questionnaire (POSQ), and the Patient Perception of Bladder Condition (PPBC).","authors":"Ergul Aslan, Önay Yalçın, Nezihe Kızılkaya Beji, Funda Güngör Ugurlucan, Habibe Ayyıldız Erkan, Goksen Ayvacıklı, Cenk Yasa, Özlem Bekdemir Kaya, Zeynep Ogul, Eda Yakıt Ak","doi":"10.1007/s00192-026-06669-6","DOIUrl":"https://doi.org/10.1007/s00192-026-06669-6","url":null,"abstract":"<p><strong>Introduction: </strong>This study aimed to translate, culturally adapt, and evaluate the psychometric properties of four patient-reported outcome measures developed for individuals with overactive bladder (OAB): the Overactive Bladder Questionnaire (OAB-Q), Urgency Questionnaire (UQ), Primary Overactive Bladder Symptom Questionnaire (POSQ), and Patient Perception of Bladder Condition (PPBC).</p><p><strong>Methods: </strong>The study included 120 women diagnosed with OAB. The Turkish adaptation of the instruments was conducted using a standardized forward-backward translation and cultural adaptation process, and content validity was assessed on the basis of expert opinions. For test-retest reliability, participants completed the questionnaires twice with a 2-week interval. Internal consistency was evaluated using Cronbach's alpha coefficient, while test-retest reliability was examined using intraclass correlation coefficients (ICC) and Cohen's kappa analysis. Construct validity was assessed using exploratory and confirmatory factor analyses. Convergent and discriminant validity were analyzed using the King's Health Questionnaire (KHQ), bladder diary variables, and the pad test.</p><p><strong>Results: </strong>Cronbach's alpha coefficients ranged from 0.781 to 0.945 for the OAB-Q and from 0.795 to 0.910 for the UQ. The total Cronbach's alpha value for the POSQ was 0.70. Test-retest results demonstrated moderate to high temporal stability across all instruments. Factor analyses supported the original factor structures of the scales. A significant and moderate correlation was found between the POSQ and the KHQ, whereas the PPBC demonstrated independent construct validity by reflecting patients' subjective perceptions of their bladder condition.</p><p><strong>Conclusion: </strong>The Turkish versions of these four instruments are valid, reliable, and culturally appropriate assessment tools for evaluating OAB symptoms, with potential utility in both clinical practice and research settings.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Molecular Signatures of Bladder Pain Syndrome: A Systematic Review Towards Phenotype-Informed Diagnostics.","authors":"Anastasia Kaltsa, Maged Morad Fouad Shendy, Grigorios Kyriazis","doi":"10.1007/s00192-026-06659-8","DOIUrl":"https://doi.org/10.1007/s00192-026-06659-8","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Bladder painsyndrome (BPS) is a disabling condition diagnosed clinically, characterised by marked heterogeneity in cystoscopic phenotype and treatment response. Molecular mechanisms remain incompletely defined, and no validated biomarkers currently support diagnosis or phenotypic stratification. The objective was to synthesise molecular evidence underpinning BPS and evaluate biomarker candidates relevant to phenotype-informed diagnostics.</p><p><strong>Methods: </strong>A Preferred Reporting Items for Systematic reviews and Meta-Analyses-guided search of PubMed and the Cochrane Library (to 24 November 2024) identified human and experimental studies reporting molecular, transcriptomic, proteomic or biochemical characterisation of BPS (including studies indexed under interstitial cystitis). Eligibility followed the SPIDER framework. Owing to heterogeneity in phenotyping, biospecimens and analytical platforms, findings were narratively synthesised and organised by mechanistic domain.</p><p><strong>Results: </strong>Twenty studies were included (316 records screened). Convergent findings supported four inter-related domains: immune activation and lymphoid recruitment, including IL6, TNF, CXCL13/CXCR5 and IL17RA-linked signalling; urothelial barrier impairment with reduced CDH1 and TJP1 and increased adhesion molecules (e.g. ICAM1); neurogenic sensitisation involving NGF, ADCYAP1 and CNR1; and inflammasome and oxidative pathways, including NLRP3, IL1B and NOS2. Where phenotypes were distinguished, Hunner-type BPS demonstrated an immune- and endoplasmic-reticulum-stress-enriched profile compared with non-Hunner disease. Across studies, biomarker signals showed limited reproducibility, constrained by small cohorts and inconsistent phenotyping.</p><p><strong>Conclusions: </strong>Current evidence supports BPS as a syndrome comprising biologically distinct endotypes spanning immune, epithelial, neurogenic and inflammasome pathways. Large, rigorously phenotyped human studies using harmonised multi-omics approaches are required to validate biomarkers and enable phenotype-informed diagnosis and targeted therapy.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147837826","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Uncorrected Defect: A Risk Stratification Model for Persistent Levator Ballooning Following Pelvic Organ Prolapse Repair.","authors":"José Antonio García-Mejido, Sara García-Pombo, Olaya Salas-Álvarez, Ana Fernández-Palacín, Fernando Bugatto-Gonzalez, José Antonio Sainz-Bueno","doi":"10.1007/s00192-026-06662-z","DOIUrl":"https://doi.org/10.1007/s00192-026-06662-z","url":null,"abstract":"<p><strong>Objective: </strong>To develop and validate a multivariable prediction model capable of identifying patients at high risk of persistent levator hiatus ballooning 3 months following primary POP reconstructive surgery.</p><p><strong>Method: </strong>A prospective observational study was conducted on a consecutive cohort of 140 women undergoing primary surgery for symptomatic POP (POP-Q stage ≥ 2). All patients underwent a standardized transperineal ultrasound assessment preoperatively and at 3 months postoperatively. Ballooning was defined as a levator hiatus area (LHA) of ≥ 25 cm² on straining maneuver. A multivariable binary logistic regression model was developed to predict the presence of postoperative ballooning. The model's performance was assessed using Harrell's C-index (AUC) and calibration plots.</p><p><strong>Results: </strong>Although surgery resulted in a significant mean reduction of the LHA on straining (from 29.60 ± 8.30 cm² to 27.17 ± 7.24 cm²; p < 0.001), the ballooning phenotype persisted in 57.1% (80/140) of the cohort. The final multivariable model identified three independent predictors: age (OR 0.959; 95% CI 0.920-0.999), body mass index (OR 1.095; 95% CI 1.004-1.194), and preoperative resting LHA (OR 1.276; 95% CI 1.158-1.405). Notably, resting area proved to be a stronger predictor than straining area. The model demonstrated high discriminative ability with an AUC of 0.84 (95% CI 0.77-0.91) and good calibration.</p><p><strong>Conclusions: </strong>Surgical correction of POP reduces hiatal dimensions but fails to correct levator ballooning in the majority of patients. We developed a highly accurate predictive model that identifies this \"uncorrected defect\" using preoperative resting biometry. Identifying this high-risk phenotype is crucial for patient counseling and managing expectations regarding long-term recurrence.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815261","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perineal Membrane Structural Changes: An Unstudied Aspect of Prolapse.","authors":"Fernanda Pipitone, Carolyn W Swenson, John O L DeLancey, James A Ashton-Miller, Luyun Chen","doi":"10.1007/s00192-026-06614-7","DOIUrl":"https://doi.org/10.1007/s00192-026-06614-7","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The perineal membrane (PM), perineal body, and levator ani muscles form the perineal complex, which is responsible for hiatal closure. Yet failures in its connective tissues that may lead to hiatal closure impairment are poorly understood. We tested the hypothesis that pelvic organ prolapse involves PM abnormalities by comparing PM morphology between young women with prolapse and parous controls using a validated MRI-based reconstruction and analysis technique.</p><p><strong>Methods: </strong>This is a secondary analysis of MRIs from two prior studies. The PM was traced on coronal scans in 3D Slicer^®, and surface models were analyzed using Rhino^®. Six PM parameters were measured: swinging door angle, visible bony origin length, hiatal anteroposterior diameter and area, PM surface area, and midline separation. Group comparisons used t tests, with Cohen's d, correlations, and stepwise regression analysis.</p><p><strong>Results: </strong>Resting MRIs from 17 young parous women (aged < 40 years) with prolapse and 20 parous controls were compared. Women with prolapse showed 23% greater midline separation of the PM, 30% larger hiatal area, 26% larger hiatal anteroposterior diameter, 17% longer bony origin, and 26% larger PM surface area (all p ≤ 0.002, d = 1.1-1.6); swinging door angle was similar between groups (p = 0.60). Levator ani status, midline separation, and PM surface area independently predicted prolapse, explaining 76% of variance.</p><p><strong>Conclusions: </strong>The PM structure was altered in those with prolapse through loss of central PM connection, hiatal elongation, and hiatal widening. Larger studies are needed to confirm and guide targeted repair techniques that could potentially prevent prolapse development and/or progression.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147815283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Recruitment in Urinary Incontinence Care: Insights from the EvidenceNOW Managing Urinary Incontinence Initiative.","authors":"Rachel M Burns, Nipher Malika, Shona Olalere Oluwatola, Gabriela Alvarado, Martha Timmer, Sangeeta Ahluwalia","doi":"10.1007/s00192-026-06658-9","DOIUrl":"https://doi.org/10.1007/s00192-026-06658-9","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Urinary incontinence (UI) affects over half of adult women but is widely underdiagnosed and undertreated in primary care due to stigma, normalization, and limited routine screening. Identifying effective recruitment strategies is essential to improving UI care in these settings.</p><p><strong>Methods: </strong>We conducted semi-structured interviews and focus groups with grantee leaders and practice facilitators (n = 32), site visits and virtual interviews with providers and staff (n = 47) and collected quarterly quantitative recruitment and retention data from five grantees participating in a nationwide UI initiative. Qualitative data were analyzed thematically using the Consolidated Framework for Implementation Research. Quantitative data, including 1950 enrolled practices and 134,852 screened patients, were summarized with descriptive statistics.</p><p><strong>Results: </strong>No single recruitment strategy was universally effective. All grantees utilized approaches such as leveraging professional relationships, engaging practice facilitators, and conducting in-person meetings, which were consistently linked to higher practice and provider recruitment. Leadership engagement facilitated recruitment success, while use of incentives and broad outreach alone were insufficient. Patient recruitment was most successful when UI screening was embedded in routine intake workflows. Across all grantees, 21% of screened patients tested positive for UI. Recruitment challenges included approval delays in large systems and increased workload related to integrating screening into routine care.</p><p><strong>Conclusions: </strong>Successful UI intervention recruitment in primary care requires combining leadership support, workflow integration, and tailored approaches. Limitations include reliance on aggregate data and absence of patient-reported perspectives or subgroup analyses. Future research should further investigate strategies to advance equitable UI care delivery.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Digital Therapeutic FEMANEA® for Women with Stress and Mixed Urinary Incontinence: A Randomized Controlled Pilot Study.","authors":"Anna Schneiderbanger, Katharina Arndt, Hannah Arnold, Matthias W Beckmann, Vesna Bjelic-Radisic, Hendrik Borgmann, Stefanie Burghaus, Emilia Fieseler, Thomas Fink, Michael Gedamke, Matthias Goetze, Anna-Lena Nachtigal, Maja Vorwerk, Bernd Wullich, Verena Lieb","doi":"10.1007/s00192-026-06670-z","DOIUrl":"https://doi.org/10.1007/s00192-026-06670-z","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This exploratory pilot study provided initial evidence of the effectiveness of the digital therapeutic (DTx) FEMANEA® for the conservative treatment of stress urinary incontinence (SUI) and mixed urinary incontinence (MUI) with a predominant stress component in women and is intended to prepare a further, more in-depth subsequent randomized controlled trial (RCT).</p><p><strong>Methods: </strong>Between May and October 2024, 81 patients (women at least 18 years old; SUI or MUI) were enrolled at five centers and randomized into an intervention group (IG, n = 34) or a control group (CG, n = 40). Both groups received standard conservative treatments (i.e., reality of care), the IG additionally had immediate access to the DTx FEMANEA®. Outcome parameters were assessed at baseline, mid-treatment (45 days), and post-treatment (90 days) using the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF), King's Health Questionnaire (KHQ), bladder diary, 24-h pad test, Patient Activation Measure (PAM-13), and app usage metrics. Data collection was carried out electronically with eCRFs (electronic case report forms) and ePROs (electronic patient reported outcomes).</p><p><strong>Results: </strong>The final analysis included 74 patients (dropout rate 6.2%). At baseline, symptom burden was slightly higher in the IG than in the CG (ICIQ-UI SF: T0 IG 10.7 ± 4.3, CG 9.2 ± 3.0; p = 0.09). The CG showed no significant improvement in symptoms (T2 8.3 ± 2.7; Δ = -0.9, p = 0.051), whereas the IG demonstrated a significant and clinically relevant reduction in symptoms (T2 8.2 ± 4.7; Δ = -2.2; p = 0.001), exceeding the minimal important difference (MID) of 1.46 points. Additionally, the KHQ subscale 2 \"incontinence impact on life\" observed a significant improvement (IG -19.8 ± 18.7 vs. CG -5.3 ± 19.8; p = 0.002), with IG improvements also being clinically relevant and surpassing the MID by a factor of four. Daily incontinence episodes decreased by 79.7% in the IG versus 48.3% in the CG (each group p < 0.01). Urinary loss volume revealed a 44.0% reduction in the IG, whereas CG values slightly increased. The mean app use in the IG was 2.6 ± 1.9 days per week per patient.</p><p><strong>Conclusions: </strong>Use of the DTx FEMANEA® resulted in clinically and statistically significant improvements in UI symptom burden (ICIQ-UI SF) and quality of life (KHQ subscale 2). These initial clinical data are intended to provide preliminary indications and prepare for the subsequent trial to be conducted.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Retrospective Cohort Study of Bilateral Sacrospinous Ligament Fixation Over a Decade of Clinical Experience.","authors":"Enrique Ubertazzi, Maria Victoria Lella Gilabert, Hector Soderini, Joaquin Prieto, Lucas Noferi, Juan Sardi","doi":"10.1007/s00192-026-06608-5","DOIUrl":"https://doi.org/10.1007/s00192-026-06608-5","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Bilateral sacrospinous ligament fixation (BSSLF) is a well-established procedure for apical prolapse repair, yet surgical approaches and outcomes vary. This study presents the first large-cohort, long-term retrospective evaluation of BSSLF using the sling-like mesh Splentis®. We analyse anterior BSSLF (ABSSLF) outcomes without total hysterectomy and compare them with other surgical approaches used in clinical practice.</p><p><strong>Methods: </strong>A total of 391 patients treated with Splentis between 2012 and 2023 at two referral centres were stratified into group A (ABSSLF without total hysterectomy, n = 248) and group B (other approaches including posterior fixation and/or total hysterectomy, n = 143). Outcomes were evaluated at intermediate (1-3 years, n = 256) and long-term follow-up (> 3 years, n = 135). Primary endpoint was composite cure: Pelvic Organ Prolapse Quantification (POP-Q) point C < 0, absence of bulge symptoms and no retreatment. Secondary endpoints included POP-Q changes, patient-reported symptoms and complications.</p><p><strong>Results: </strong>Overall cure was 90.3% (95% CI 86.9-93.0%): group A, 94.3% (95% CI 90.7-96.9%); group B, 83.2% (95% CI 76.1-88.9%). Group A remained stable at long-term follow-up, whereas group B declined by 16.2 percentage points. Omission of concomitant anterior colporrhaphy was associated with higher odds of treatment failure (OR 3.0, 95% CI 1.3-6.8; p = 0.010). Most complications were Clavien-Dindo ≤ II. Mesh-related complications were 4.8% (95% CI 2.5-8.3%) in group A and 5.6% (95% CI 2.4-10.7%) in group B.</p><p><strong>Conclusions: </strong>The ABSSLF procedure using Splentis showed high long-term effectiveness when used for hysteropexy or cervicopexy, that is, without prior/concomitant total hysterectomy. Other approaches showed lower yet favourable outcomes, highlighting the versatility of the device and the importance of patient selection.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147770742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Pelvic Organ Prolapse Misconceptions Scale for Hispanic Women.","authors":"Alyse Victor, Joshua Fogel, Roshaye Graham, Neha Doddipalli, Errol Thompson","doi":"10.1007/s00192-026-06653-0","DOIUrl":"https://doi.org/10.1007/s00192-026-06653-0","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Misconceptions about pelvic organ prolapse occur among Hispanic women. We develop and validate a novel scale measuring misconceptions about pelvic organ prolapse (POP) among Hispanic women.</p><p><strong>Methods: </strong>A cross-sectional survey of 406 Hispanic women was conducted. Participants completed 11 items about POP misconceptions, the Prolapse and Incontinence Knowledge Questionnaire (PIKQ-POP), and the Short Acculturation Scale for Hispanics (SASH). Principal component analysis was used.</p><p><strong>Results: </strong>The Pelvic Organ Prolapse Misconceptions Scale (POPMS) had two subscales: personal habits and sequelae (PHS) and treatment approaches (TA), with high internal reliability (KR-20 = 0.90 and 0.81, respectively). The POPMS PHS and TA subscales were each positively correlated (both r = 0.25, p < 0.001) with general POP knowledge of the PIKQ-POP. College-educated women had higher mean scores on the PHS (p < 0.001) and TA (p = 0.01) than those not college educated. The correlations and mean scores indicate acceptable criterion validity. Misconceptions were common: 44% answered all PHS items incorrectly, and 56% answered all TA items incorrectly. The PIKQ-POP was positively associated with three SASH acculturation subscales (all p < 0.001). The POPMS was not associated with any of the three SASH acculturation subscales.</p><p><strong>Conclusions: </strong>In conclusion, the POPMS is a valid and reliable instrument to measure misconceptions about POP in Hispanic women. Importantly, while general POP knowledge correlates with acculturation, misconceptions do not. This shows that misinformation may persist even in more acculturated individuals. We recommend that clinicians consider administering the POPMS scale to their Hispanic patients. This will allow clinicians to better understand their patients' misconceptions about POP.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking Peer Review - Engaging Early Career Researchers and Promoting Disciplinary Diversity.","authors":"Baerbel Junginger","doi":"10.1007/s00192-026-06673-w","DOIUrl":"https://doi.org/10.1007/s00192-026-06673-w","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter Regarding \"Bone-Targeted High-Intensity Training Does Not Reduce Quality of Life Related to Pelvic Floor Dysfunction: The MEDEX-OP Randomized Controlled Trial\".","authors":"Melanie Kistler-Fischbacher, Benjamin K Weeks, Belinda R Beck","doi":"10.1007/s00192-026-06624-5","DOIUrl":"https://doi.org/10.1007/s00192-026-06624-5","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2026-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}