{"title":"Comment on \"Symptomatic Pelvic Floor Disorders in Community-Dwelling Women in Central Gondar Zone, Northwest Ethiopia\".","authors":"Liqin Gu, Ruohui Huang","doi":"10.1007/s00192-025-06226-7","DOIUrl":"https://doi.org/10.1007/s00192-025-06226-7","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144674790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hannah Ruetten, Rory Ritts, Mary Namugosa, Wencheng Li, Robert Evans, Gopal Badlani, Stephen J Walker
{"title":"Mast Cells and Interstitial Cystitis/Bladder Pain Syndrome Revisited.","authors":"Hannah Ruetten, Rory Ritts, Mary Namugosa, Wencheng Li, Robert Evans, Gopal Badlani, Stephen J Walker","doi":"10.1007/s00192-025-06213-y","DOIUrl":"https://doi.org/10.1007/s00192-025-06213-y","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>There is significant variation in interstitial cystitis/bladder pain syndrome (IC/BPS) biopsy processing and reporting. The objective of this study was to review pathology reports from a large IC/BPS patient cohort to identify differences in findings. We hypothesize that variation in IC/BPS bladder biopsy reporting might be most frequent when it comes to mast-cell counts.</p><p><strong>Methods: </strong>We performed a retrospective analysis of 461 diagnostic pathology reports collected from our IRB-approved prospective study of patients diagnosed with IC/BPS at the Urology Clinic at Wake Forest Baptist Hospital from October 2011 to July 2023 (IRB00018552). Data were assigned as continuous or categorical variables. Groups were compared using Student's t test, Mann-Whitney, or Chi-squared tests.</p><p><strong>Results: </strong>Staining strategy for mast-cell visualization differed between pathologists and included in order of frequency mast-cell tryptase (TPSAB1), CD117 (KIT), unspecified stain, a combination of stains, and toluidine blue. Mast-cell count was reported as a single number, range, or qualitatively. Pathologists used units of high-powered field (HPF), mm<sup>2</sup>, or did not specify. As expected, average mast-cell count per HPF was significantly lower than per mm<sup>2</sup> across all stains (p < 0.0001). Average count with KIT was significantly lower than TPSAB1 (p < 0.0001). This trend remained significant when considering only KIT and TPSAB1 counts per HPF (p = 0.0007). Additionally, reports identified squamous metaplasia, acute inflammation, and/or chronic inflammation.</p><p><strong>Conclusions: </strong>There is a lack of standardization regarding histological analysis of bladder biopsies from patients with IC/BPS, leading to inconsistent data and confusion surrounding the significance of pathology report findings.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Marie Douglass, Katharina Laus, Samantha DeAndrade, Taylor Whitaker, Tajnoos Yazdany, Christina Truong
{"title":"Evaluation of the Safety of Virtual Visits After In-Clinic Botox® Injection: A Quality Improvement Study.","authors":"K Marie Douglass, Katharina Laus, Samantha DeAndrade, Taylor Whitaker, Tajnoos Yazdany, Christina Truong","doi":"10.1007/s00192-025-06216-9","DOIUrl":"https://doi.org/10.1007/s00192-025-06216-9","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Virtual visits can be performed after in-clinic injection of Botox®, but data are lacking on the safety of these visits. The aim of this study was to evaluate the effects of a protocol change from in-person to virtual post-procedure visits after in-clinic injection of Botox®.</p><p><strong>Methods: </strong>This was a quality improvement study that took place at a safety-net hospital. Initially, all patients undergoing Botox® injection for idiopathic overactive bladder were scheduled for a 2-week in-person assessment after their procedure. Beginning in January 2023, patients were instead scheduled for a 2-week phone visit where they were screened using standardized and validated questionnaires and asked to present for in-person assessment if they expressed worsening or concerning symptoms. Demographic variables, subjective improvement, need for in-person assessment, and rates of urinary tract infection and retention were compared between groups.</p><p><strong>Results: </strong>Fifty-seven patients in the in-person-visit group and 60 in the phone-visit group were included. There was no difference in subjective improvement, symptoms of dysuria or incomplete emptying, or rates of urinary tract infection or retention between groups. Twenty-eight percent of patients who had phone visits were asked to return in-person, although this did not correspond with a higher rate of complications. The phone-visit group had a 68.3% reduction in face-to-face assessments overall when compared with the in-person group.</p><p><strong>Conclusions: </strong>Post-procedure phone visits are safe and feasible to perform after in-clinic Botox® injection, and are not associated with an increased risk of complications.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Feedback on \"Comment on 'Development and Validation of Risk Assessment Model for Pelvic Organ Prolapse Based on A Retrospective Study with Machine Learning Algorithm'\".","authors":"Ling Mei, Xiaoyu Niu","doi":"10.1007/s00192-025-06227-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06227-6","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"Standing Postural Balance Control in Women with and Without Urinary Incontinence: A Systematic Review\".","authors":"Venkata Dileep Kumar Veldi, Rachana Mehta, Ranjana Sah","doi":"10.1007/s00192-025-06219-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06219-6","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144659171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Apiwat Jongjakapun, Teerayut Temtanakitpaisan, Jen Sothornwit, Porjai Pattanittum, Chetta Ngamjarus
{"title":"Pectopexy for Pelvic Organ Prolapse: A Scoping Review.","authors":"Apiwat Jongjakapun, Teerayut Temtanakitpaisan, Jen Sothornwit, Porjai Pattanittum, Chetta Ngamjarus","doi":"10.1007/s00192-025-06232-9","DOIUrl":"https://doi.org/10.1007/s00192-025-06232-9","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Pectopexy is an emerging surgical technique for apical pelvic organ prolapse, anchoring the prolapsed structure to the iliopectineal ligament. This review aims to systematically map the available evidence on pectopexy, including study characteristics, surgical techniques, and reported outcomes.</p><p><strong>Methods: </strong>A systematic search was conducted across PubMed, Scopus, CENTRAL, CINAHL, LILACS, ClinicalTrials.gov, ProQuest, and OpenGrey, alongside citation searches. Eligible studies included those assessing pectopexy for apical pelvic organ prolapse (POP-Q stage ≥ 2). Randomised controlled trials (RCTs), cohort studies, and descriptive studies were included, while case reports and reviews were excluded. Study selection and data extraction were independently conducted by two reviewers, with findings summarised through descriptive synthesis.</p><p><strong>Results: </strong>Thirty studies (2715 women) were eligible, which included four RCTs (13.3%), 10 cohort studies (33.3%), and 16 descriptive studies (53.3%). Most studies were conducted in Asia (66.7%), high-income economies (46.7%), and in tertiary care centres (86.7%). Pectopexy was primarily performed laparoscopically (86.7%), with bilateral fixation (86.7%) and using polypropylene mesh (46.7%). Eighty-five unique outcomes were reported. Commonly reported perioperative outcomes included operative time (86.7%), blood loss (50.0%), and length of hospital stay (50.0%). Recurrence of apical prolapse (90.0%), stress urinary incontinence (60.0%), and complications related to fixation material (53.3%) were frequently documented. No studies reported recurrence of prolapse symptoms, and the most frequent patient-reported outcome measure (PROM) was P-QOL (23.3%).</p><p><strong>Conclusions: </strong>The reported pectopexy procedures and outcomes were heterogeneous. Current evidence is limited, particularly from RCTs and low-resource settings. Subjective outcomes and PROMs were underreported.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
İsmail Emre Ergin, Aydemir Asdemir, Hüseyin Saygın, Esat Korğalı
{"title":"Impact of Weekly Application Frequency on the Efficacy of Tibial Nerve Stimulation Therapy in the Treatment of Overactive Bladder.","authors":"İsmail Emre Ergin, Aydemir Asdemir, Hüseyin Saygın, Esat Korğalı","doi":"10.1007/s00192-025-06217-8","DOIUrl":"https://doi.org/10.1007/s00192-025-06217-8","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Electrical stimulation, which has become widely used in the treatment of overactive bladder (OAB) to reduce symptoms, is a treatment method included in guidelines. However, there are shortcomings in the standardization of its application. This study is aimed at investigating the response to different frequencies of posterior tibial nerve stimulation (PTNS) in this context.</p><p><strong>Methods: </strong>Male and female patients aged 18-65 with refractory OAB were included in the study. Participants were divided into two groups. One group received PTNS treatment once a week for 12 weeks (group 1), whereas the other group received PTNS treatment twice a week (group 2). All patients completed a 3-day voiding diary before starting PTNS treatment, recording frequency, nocturia, urgency, urge incontinence, and voided volume values. The International Continence Interrogation Questionnaire Short Form (ICIQ-SF), Overactive Bladder Questionnaire (OAB-V8), and Overactive Bladder Questionnaire Short Form (OAB-q SF) were completed. Patients filled out the same voiding diary and questionnaires at the 4th and 12th weeks.</p><p><strong>Results: </strong>When the scores at the 4th and 12th weeks were compared with the baseline, there was a significant difference in both groups (repeated measures analysis of variance [ANOVA], p < 0.001). Similarly, the scores for OAB-q SF, ICIQ-SF, and OAB-V8 at the 4th and 12th weeks were significantly different in both groups compared with baseline (ANOVA, p < 0.001). When response rates were evaluated, the 12th-week results were similar in the two groups for all questionnaires (p > 0.05). However, there was a difference in the ICIQ-SF and OAB-V8 forms. At the 4th week, the results for these two questionnaires differed between the groups (p = 0.03, 0.002). When the treatment response was compared, the difference from baseline in the frequency and urgency parameters at the 4th week was greater in group 2, and this difference was statistically significant (p = 0.031, 0.015). However, this was not the case for the 12th week, where no significant difference was found between the groups (p = 0.12, 0.22).</p><p><strong>Conclusions: </strong>This study was conducted to address the lack of standardization in PTNS, a treatment method strongly recommended in European urology guidelines for the treatment of OAB. Significant improvements in voiding diary parameters were observed in both treatment groups, but the group receiving two sessions per week showed faster improvement at the 4th week, although the results were similar by the 12th week. Early improvement may be associated with a faster neuromodulation response in patients with severe symptoms. These results highlight the importance of individualized treatment protocols and suggest that further prospective studies might be needed to assess the long-term effectiveness of PTNS.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Innovative Application of Mobile Health Management Combined with the Teach-Back Method in the Rehabilitation of Pelvic Floor Muscle in Postpartum Women with Urinary Incontinence.","authors":"Xia Xiao, Chen-Hua Zhang, Yan-Meng Yang, Wei-Wei Yan, Xiao-Jing Li, Hui-Ling Shang","doi":"10.1007/s00192-025-06229-4","DOIUrl":"https://doi.org/10.1007/s00192-025-06229-4","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This study aimed to evaluate the combined effect of the teach-back method and a mobile application on maternal pelvic floor muscle rehabilitation, with a focus on reducing urinary incontinence and establishing an optimal health education approach.</p><p><strong>Methods: </strong>From January 2022 to January 2023, a total of 90 postpartum women were randomly assigned to either a control or an intervention group. The control group received standard pelvic floor exercises and health education, while the intervention group received additional education utilizing the teach-back method in conjunction with a mobile application. Outcomes assessed included urinary incontinence, pelvic floor muscle function, knowledge acquisition, and exercise compliance.</p><p><strong>Results: </strong>The intervention group demonstrated significantly better outcomes compared to the control group in primary measures. Specifically, the degree of urinary incontinence, as assessed by the 1-h urine pad test, was lower in the intervention group (3.2 ± 1.1 g) than in the control group (4.8 ± 1.3 g), and pelvic floor muscle function, measured by the Oxford muscle strength score, was higher in the intervention group (4.2 ± 0.6 grade) compared to the control group (3.1 ± 0.8 grade) (p < 0.01). For secondary outcomes, the knowledge mastery rate was higher in the intervention group (82.0%) than in the control group (66.4%), and exercise compliance was also significantly improved in the intervention group (p < 0.05). Additionally, the severity of urinary incontinence was found to be negatively correlated with pelvic floor muscle function, while increased awareness was identified as a positive predictor of compliance.</p><p><strong>Conclusions: </strong>The teach-back method combined with mobile apps can effectively reduce the degree of urinary incontinence, promote the recovery of pelvic floor function, and improve rehabilitation cognition and compliance. The research reported in this publication was approved by the self-funded research project of Handan Bureau of Science and Technology, Hebei Province, China,project number: 22422083030ZC.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia K Shinnick, Omar Najjar, Gabrielle Jude, Megan M Lobel, Matthew M Scarpaci, Nicole B Korbly
{"title":"Prolapse and Incontinence Knowledge Before Versus After an Initial Urogynecology Consultation.","authors":"Julia K Shinnick, Omar Najjar, Gabrielle Jude, Megan M Lobel, Matthew M Scarpaci, Nicole B Korbly","doi":"10.1007/s00192-025-06203-0","DOIUrl":"https://doi.org/10.1007/s00192-025-06203-0","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The objective was to compare Prolapse and Incontinence Knowledge Questionnaire (PIKQ) scores before versus after initial consultation with a Urogynecology physician. Secondary objectives included examining correlations between PIKQ scores, symptom severity, and satisfaction.</p><p><strong>Methods: </strong>A prospective study of new patients, aged ≥ 18 years, referred to an academic tertiary referral center for urinary incontinence or pelvic organ prolapse, was carried out. Participants self-reported demographic information and completed the PIKQ (scores range 0-24; 2 subscales: urinary incontinence, pelvic organ prolapse; higher scores indicate greater knowledge) before and after the visit. Questionnaires assessing symptom severity and satisfaction were also completed. Assuming a mean score of 15 ± 6 (α 0.05, β 0.20), 90 participants were required to detect a moderate effect size (0.3). Pearson correlation coefficients, p tests, and regression models were applied as appropriate.</p><p><strong>Results: </strong>Ninety-four participants, with a mean age 56 ± 13.5 years, were included. Primary diagnoses included overactive bladder (60 out of 94, 64%), stress urinary incontinence (57 out of 94, 61%), and pelvic organ prolapse (36 out of 94, 38%). Mean pre-visit PIKQ score was 15.8 ± 6.2, which increased post-visit (2.4 ± 5.2 points, p < 0.001). Neither pre-visit PIKQ score nor change in score correlated with treatment decision satisfaction (correlation coefficient -0.07, p = 0.52). Symptom severity did not correlate with PIKQ score change, although weak correlations between symptom severity and pre-visit scores were noted (correlation coefficients ranged from -0.22 to -0.31, p < 0.05).</p><p><strong>Conclusion: </strong>The PIKQ scores increased after initial Urogynecology consultation, and changes correlated with neither symptoms nor satisfaction.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Matrix Radiofrequency Combined with Myofascial Manipulation in the Treatment of Myofascial Pelvic Pain: A Retrospective Study.","authors":"Hongyan Wang, Wenying Wang, Fangfang Xue","doi":"10.1007/s00192-025-06202-1","DOIUrl":"https://doi.org/10.1007/s00192-025-06202-1","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This study is aimed at evaluating the clinical efficacy of matrix radiofrequency combined with myofascial manipulation in the treatment of myofascial pelvic pain (MPP) and to assess its effects on pain relief and pelvic floor muscle function improvement.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 87 MPP patients treated at our hospital between January 2021 and December 2024. According to their treatment modalities, patients were divided into the observation group (matrix radiofrequency combined with myofascial manipulation) and the control group (myofascial manipulation alone). Pain levels and pelvic floor muscle function were assessed using the Visual Analog Scale (VAS) and pelvic floor surface electromyography by Glazer evaluation before and after treatment in both groups.</p><p><strong>Results: </strong>After the treatment course, the VAS scores significantly decreased in both groups. However, the post-treatment VAS score in the observation group (1.21 ± 0.95) was significantly lower than that in the control group (2.76 ± 0.80), with a statistically significant difference between the two groups (p < 0.001). The Glazer evaluation of pelvic floor muscles showed that the improvements in fast-twitch contraction, tonic contraction, and endurance contraction in the observation group were significantly greater than those in the control group (p < 0.001), and the reduction in resting electromyographic amplitude was also more pronounced. Moreover, the overall effective rate in the observation group was significantly higher than that in the control group (p < 0.05).</p><p><strong>Conclusion: </strong>Matrix radiofrequency combined with myofascial manipulation is significantly more effective than myofascial manipulation alone in alleviating pain and improving pelvic floor muscle function in patients with MPP. This combination therapy provides a safe and effective treatment option, which can significantly improve the clinical efficacy of patients.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}