International Urogynecology Journal最新文献_第10页

Special Edition on Sacrocolpopexy: A Worldwide Effort. 特别版：世界范围的努力。

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-01 Epub Date: 2025-01-18 DOI: 10.1007/s00192-025-06056-7

Catherine A Matthews

引用次数: 0

A Cross Sectional Study of Cytokines in Women with Refractory Detrusor Overactivity versus Controls. 难治性逼尿肌过度活动女性与对照组细胞因子的横断面研究。

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-01 Epub Date: 2024-11-19 DOI: 10.1007/s00192-024-05999-7

Kylie J Mansfield, Zhuoran Chen, Samantha Ognenovska, Nancy Briggs, Ronald Sluyter, Kate H Moore

{"title":"A Cross Sectional Study of Cytokines in Women with Refractory Detrusor Overactivity versus Controls.","authors":"Kylie J Mansfield, Zhuoran Chen, Samantha Ognenovska, Nancy Briggs, Ronald Sluyter, Kate H Moore","doi":"10.1007/s00192-024-05999-7","DOIUrl":"10.1007/s00192-024-05999-7","url":null,"abstract":"Introduction and hypothesis: Previous work has suggested that refractory detrusor overactivity (DO) was commonly associated with urinary tract infection (UTI), which can lead to inflammatory changes in the bladder. This study aimed to investigate the concentrations of urinary cytokines in a large sample of women with refractory detrusor overactivity (DO) and age matched controls.Methods: The urinary concentration of 27 cytokines in 140 women (95 with refractory DO and 45 age matched controls (women without urge incontinence)) was determined using the Human Cytokine 27-plex Assay. Cytokine concentrations were correlated with a \"UTI score\", the presence or absence of bacteriuria or pyuria on the day of sample collection and a previous history of UTI.Results: Pro-inflammatory cytokines were increased in refractory DO women compared to the controls. In women with refractory DO, the UTI score significantly correlated with urinary cytokine concentrations in 15 of the 22 cytokines detected. A previous history of UTI did not affect urinary cytokine concentrations in refractory DO women with no current UTI. Increasing pyuria was associated with increasing concentrations of urinary cytokines.Conclusion: Careful comparison of cytokine concentrations in women with refractory DO versus age matched controls has shown that changes in pro-inflammatory cytokines are related to the UTI disease burden, suggesting that an underlying inflammatory response, together with UTI, may be an aetiological contributor to the development of refractory DO.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"351-361"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142667896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the Work Productivity Impact of Overactive Bladder Syndrome Among Employees at a Brazilian Hospital. 评估膀胱过度活动症对巴西一家医院员工工作效率的影响。

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-02-01 Epub Date: 2024-11-09 DOI: 10.1007/s00192-024-05985-z

Marta Q S Fontenele, Janaina M O Nunes, Fuad A Hazime, Silvio H M de Almeida

{"title":"Assessing the Work Productivity Impact of Overactive Bladder Syndrome Among Employees at a Brazilian Hospital.","authors":"Marta Q S Fontenele, Janaina M O Nunes, Fuad A Hazime, Silvio H M de Almeida","doi":"10.1007/s00192-024-05985-z","DOIUrl":"10.1007/s00192-024-05985-z","url":null,"abstract":"Introduction and hypotheses: Few studies have investigated the relationship between work productivity (WP) and overactive bladder syndrome (OABS). The majority of those that do use generic productivity questionnaires or only include WP as a secondary outcome. We evaluated the impact of OABS on specific domains of WP, with the hypothesis that OABS has an impact on the domains of efficiency, concentration, vigor, and irritability, lost working hours, interruptions, and impairment to the work schedule.Methods: An observational, cross-sectional study with 576 female employees (without SBH 447, dry OABS 63, wet OABS 66) was carried out. The 8-item Overactive Bladder Questionnaire (OAB-V8), International Consultation on Incontinence Questionnaire Overactive Bladder (ICIQ-OAB), and a WP questionnaire developed by the authors were used. Non-parametric tests were adopted to associate OABS with productivity. The correlation between the instruments was performed using the Spearman test, adopting a value of p = 0.05.Results: There was a significant impact of urinary symptoms on WP (p = 0.03) in the domains of productivity/efficiency (p = 0.03), restlessness (p < 0.05), and interruptions to go to the bathroom (p = 0.03), which was higher among employees with wet OABS. Urgency and urge urinary incontinence (UUI) were the symptoms with the greatest productive impact (p = 0.01, p < 0.001). A significant correlation was found between WP scores and OAB-V8 and ICIQ-AOB scores in both groups (p < 0.05).Conclusion: OABS impacted WP, in the domains of efficiency, restlessness, and interruptions to go to the bathroom, with urgency and UUI being the symptoms with the greatest impact on productivity.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"317-330"},"PeriodicalIF":1.8,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluating the Benefit of a Urogynecologic Telehealth Consultation after Obstetric Anal Sphincter Injury.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-01-31 DOI: 10.1007/s00192-025-06077-2

Kyra Bonasia, Susan Luong, Jocelyn Stairs, Aisling Clancy

{"title":"Evaluating the Benefit of a Urogynecologic Telehealth Consultation after Obstetric Anal Sphincter Injury.","authors":"Kyra Bonasia, Susan Luong, Jocelyn Stairs, Aisling Clancy","doi":"10.1007/s00192-025-06077-2","DOIUrl":"https://doi.org/10.1007/s00192-025-06077-2","url":null,"abstract":"Introduction: Obstetric anal sphincter injuries (OASI) are associated with significant risk of complications, including pain, infection, and long-term pelvic floor dysfunction. The primary aim of this study was to evaluate the utility and acceptability of a postpartum telehealth consultation focused on pelvic floor health for patients after OASI.Methods: This prospective study used a pre-post design comparing standard postpartum care versus standard postpartum care plus a telehealth urogynecology consultation focused on pelvic floor recovery. The primary outcome was symptom burden as measured by the Pelvic Floor Distress Inventory (PFDI-20) score 16-weeks postpartum. Patient experience was evaluated using the QQ10 and the Patient Enablement Instrument. T-tests and chi-squared tests were used to compare groups.Results: A total of 119 participants completed study activities (control group n = 62, intervention group n = 57). There was no significant difference between the two groups in PFDI-20 scores (55.6 versus 46.6, p = 0.23). The individual items most likely to be endorsed among all participants were related to flatal incontinence (52.1%) and fecal urgency (49.6%). For the subset analysis of 35 patients with severe OASI (3C or fourth-degree tears), those who had a telehealth consultation had lower PFDI-20 scores (56.6 versus 34.7; p = 0.04). QQ10 estimated a value score of 79/100 and a burden score of 18/100 for the telehealth consultation.Conclusions: A postpartum telehealth consultation focused on pelvic floor health may benefit patients with severe OASI who reported reduced symptom burden. Participants rated a telehealth consultation as high value and low burden for this condition.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy of 100-U Onabotulinumtoxin A Treatment in Female Idiopathic Overactive Bladder-A Prospective Follow-Up Study.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-01-31 DOI: 10.1007/s00192-025-06047-8

Mona Nurkkala, Heini Salo, Terhi Piltonen, Henri Sova, Henna-Riikka Rossi

{"title":"Efficacy of 100-U Onabotulinumtoxin A Treatment in Female Idiopathic Overactive Bladder-A Prospective Follow-Up Study.","authors":"Mona Nurkkala, Heini Salo, Terhi Piltonen, Henri Sova, Henna-Riikka Rossi","doi":"10.1007/s00192-025-06047-8","DOIUrl":"https://doi.org/10.1007/s00192-025-06047-8","url":null,"abstract":"Introduction and hypothesis: Overactive bladder (OAB) affects 11-17% of the female population. First-line treatment with lifestyle modifications and second-line therapy with medications are often limited by inadequate efficacy or pharmacological side effects. This study was aimed at assessing the effect of 100 U onabotulinumtoxin A treatment on idiopathic OAB (iOAB) as a second-line treatment.Methods: This prospective follow-up study involved 94 women who received onabotulinumtoxin A treatment at a dose of 100 U as a second-line treatment for iOAB at the Department of Obstetrics and Gynecology, Oulu University Hospital, Finland, between May 2018 and December 2023. The impact of the treatment on iOAB symptoms was evaluated 3 months after administration using self-reported symptoms and the following internationally validated questionnaires: Visual Analogue Scale (VAS), Incontinence Impact Questionnaire (IIQ-7), and Urogenital Distress Inventory (UDI-6). Postoperative complications were assessed.Results: The follow-up data were obtained from 74 (78%) patients, of whom 66 (95.7%) reported a good outcome and 3 (4.3%) reported a poor outcome. Incontinence episodes, the number of incontinence pads needed, and daily micturitions were significantly reduced. For all questionnaires, the total scores decreased significantly after the treatment (VAS 8.27 ± 1.78 vs 3.50 ± 3.08, p < 0.001; IIQ-7 72.14 ± 20.55 vs 28.73 ± 29.40, p < 0.001; UDI-6 55.01 ± 18.86 vs 29.66 ± 22.03, p < 0.001). Postoperative urinary tract infection occurred in 9 patients (9.6%), whereas urinary retention occurred in 6 patients (6.4%).Conclusions: Onabotulinumtoxin A (100 U) demonstrates good effectiveness in the second-line treatment of female iOAB.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Informed Consent in Pelvic Reconstructive Surgery: Patients' Perspective of a Tertiary Service Process.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-01-31 DOI: 10.1007/s00192-025-06055-8

Vandna Verma, Hayser Medina Lucena, Ivilina Pandeva, Ashish Pradhan

{"title":"Informed Consent in Pelvic Reconstructive Surgery: Patients' Perspective of a Tertiary Service Process.","authors":"Vandna Verma, Hayser Medina Lucena, Ivilina Pandeva, Ashish Pradhan","doi":"10.1007/s00192-025-06055-8","DOIUrl":"https://doi.org/10.1007/s00192-025-06055-8","url":null,"abstract":"Introduction and hypothesis: Obtaining informed consent to surgery is essential for ethical, legal, and quality-care reasons. This study evaluates patients' understanding, experience, and satisfaction with the informed consent process prior to pelvic reconstructive surgery.Methods: A prospective study was conducted from April 2021 to April 2022, registered as a service evaluation project. It included all consenting women undergoing pelvic reconstructive surgery. A standardised questionnaire with closed and open-ended questions assessed patients' experiences and decision-making evaluated using the Decisional Conflict Scale (DCS). Satisfaction was evaluated through a five-point Likert scale and a ten-point visual analogue scale (VAS) for response reliability.Results: The study included 87 patients with a mean age of 61.4 years (SD 11.4). A significant 96.6% read the consent form thoroughly, 98% affirmed detailed explanations by staff, and 88.5% found the explanation clear. Although 83.9% considered the surgery details sufficient, 16.1% found the information overly detailed or too brief. Most patients (91.9%) felt that they had ample time to think before signing, and 75.9% deemed both oral and written information helpful. Only 13.8% preferred medical staff to decide for them, whereas 55.2% valued being included in decision making. Key factors influencing satisfaction were detailed procedure information (72.4%) and reading the consent form (51.7%). The mean DCS score was 7, indicating a high level of satisfaction. Overall, 85% were very satisfied or satisfied with the consent process, with 89.7% scoring 8-10 on the VAS scale.Conclusions: A thorough consent process is associated with high patient satisfaction and facilitates shared decision making.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Telehealth vs Clinic Postoperative Visit After Hysterectomy: A Randomized Controlled Trial.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-01-31 DOI: 10.1007/s00192-025-06070-9

Susan D Wherley, David Sheyn, Leah H Hellerstein, Hope Bauer, Jeffrey Mangel, Sarah Sears, Linda-Dalal Shiber, Robert Pollard

{"title":"Telehealth vs Clinic Postoperative Visit After Hysterectomy: A Randomized Controlled Trial.","authors":"Susan D Wherley, David Sheyn, Leah H Hellerstein, Hope Bauer, Jeffrey Mangel, Sarah Sears, Linda-Dalal Shiber, Robert Pollard","doi":"10.1007/s00192-025-06070-9","DOIUrl":"https://doi.org/10.1007/s00192-025-06070-9","url":null,"abstract":"Introduction and hypothesis: Telehealth is becoming more common, but there is a paucity of literature investigating the role of telehealth in perioperative gynecologic care. The authors hypothesized that patients evaluated via telehealth 4 weeks after minimally invasive hysterectomy would not have lower satisfaction than patients evaluated in clinic.Methods: This was a randomized controlled noninferiority trial of patients who underwent minimally invasive hysterectomy at a single academic medical center. Participants were randomized to postoperative clinic visit or telehealth visit 4 weeks after hysterectomy. After the 4-week postoperative visit, patients were sent a satisfaction questionnaire. The primary outcome was overall patient satisfaction on a 100 mm visual analog scale. Secondary outcomes were 90-day postoperative complications and unplanned events.Results: One hundred one patients who underwent minimally invasive hysterectomy were identified for inclusion. Complete data were collected for 47 in the clinic group and 45 in the telehealth group. Overall postoperative visit satisfaction did not differ between groups (94.3 clinic vs. 92.0 telehealth, p = 0.47). The clinic group was significantly more likely to contact the clinic two or more times (p = 0.02); both groups were similarly likely to contact the clinic at least once (57.4% vs. 51.1%). Postoperative complications did not differ between groups, nor did unplanned clinic visits or emergency department (ED) visits.Conclusions: Postoperative visit satisfaction of patients evaluated via telehealth was noninferior to the satisfaction of patients seen in the clinic 4 weeks after minimally invasive hysterectomy. Unplanned clinic visits and ED visits did not differ between groups, nor did 90-day postoperative complications.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficacy and Tolerance of the Tampsec Vaginal Tampon for Treating Stress Urinary Incontinence. A Randomized Controlled Trial.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-01-30 DOI: 10.1007/s00192-025-06060-x

Irene Diez-Itza, Jordi Cassadó, Alicia Martin, Eloy Muñoz, Elisa López-Herrero, Celia Bauset, Mikel Mancisidor, Cristina Sarasqueta

{"title":"Efficacy and Tolerance of the Tampsec Vaginal Tampon for Treating Stress Urinary Incontinence. A Randomized Controlled Trial.","authors":"Irene Diez-Itza, Jordi Cassadó, Alicia Martin, Eloy Muñoz, Elisa López-Herrero, Celia Bauset, Mikel Mancisidor, Cristina Sarasqueta","doi":"10.1007/s00192-025-06060-x","DOIUrl":"https://doi.org/10.1007/s00192-025-06060-x","url":null,"abstract":"Introduction and hypothesis: Stress urinary incontinence (SUI) is a highly prevalent condition in women. We hypothesized that the Tampsec™ vaginal tampon will be efficacious and well tolerated in its treatment.Methods: This was a multicenter open-label parallel-group randomized control trial. All participants were recommended to make lifestyle modifications and perform pelvic floor muscle training for SUI treatment. Additionally, women in the tampon group were instructed to use a Tampsec™ throughout the day. The primary outcome measure was a ≥50% reduction in pad weight by the end of treatment. Secondary outcome measures were women's perception of improvement evaluated using the Patient Global Impression of Improvement (PGI-I) questionnaire, decrease in the mean number of SUI episodes/day, and improvement in the impact of urinary incontinence (UI) on everyday life. Tampon tolerance and usability were also evaluated.Results: Forty-six women with a positive urinary stress test were randomized 1:1 to tampon or control treatments. Regarding the primary outcome, a ≥50% reduction was achieved in 69.9% of patients in the tampon group and 26.1% in controls (RR 2.7; 95%CI 1.3-5.4). On the basis of PGI-I responses, the treatment was successful in 60.9% of women in the tampon group and 17.4% of controls (p = 0.003). The tampon group also reported greater decreases in SUI episodes/day (mean 2.0±2.2 vs 0.5±1.1; p = 0.007) and more improvement in the impact of UI on everyday life. Tolerance and usability were good in most women.Conclusion: The Tampsec™ tampon is efficacious and well tolerated in women with SUI. This treatment decreases the number of SUI episodes/day and improves UI-related quality of life.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Effect of Health Fatalism and Health-Seeking Behaviors on the Frequency of Non-Medication Coping Strategy Use in Women with Urinary Incontinence in Türkiye.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-01-30 DOI: 10.1007/s00192-025-06054-9

Şükran Başgöl, Burcu Küçükkaya

{"title":"The Effect of Health Fatalism and Health-Seeking Behaviors on the Frequency of Non-Medication Coping Strategy Use in Women with Urinary Incontinence in Türkiye.","authors":"Şükran Başgöl, Burcu Küçükkaya","doi":"10.1007/s00192-025-06054-9","DOIUrl":"https://doi.org/10.1007/s00192-025-06054-9","url":null,"abstract":"Introduction and hypothesis: Health-seeking behavior is habitual among people in a society, resulting from the interaction and balance between health needs, health resources, and socioeconomic factors. This study seeks to investigate the influence of health fatalism and health-seeking behaviors on the frequency of non-medication coping strategy use among women with urinary incontinence in Türkiye.Methods: This cross-sectional study was conducted between 8 August 2024, and 22 September 2024. A total of 354 women voluntarily participated in the study, which was disseminated via social media platforms and online forums. Data collection involved the use of a Personal Information Form, the Health Fatalism Scale (HFS), the Health-Seeking Behaviour Scale (HSBS), and the Non-Medication Coping Strategies for Urinary Incontinence Frequency of Use Scale (NMCS-UIFUS).Results: The mean total HFS score was 50.39 ± 29.70, the mean total HSBS score was 38.76 ± 20.48, and the mean NMCS-UIFUS score was 35.69 ± 17.31. A statistically significant, strong negative correlation was found between health fatalism and health-seeking behavior, whereas a significant, strong positive correlation was observed between health fatalism and the frequency of non-medication coping strategy use for urinary incontinence (p < 0.001). Regression analysis revealed that health fatalism explained 37% of the variance in the frequency of non-medication coping strategy use for urinary incontinence, whereas health-seeking behavior accounted for 30% of the variance (p < 0.001).Conclusions: Our study demonstrated that women with urinary incontinence exhibit moderate levels of health fatalism, health-seeking behaviors, and the frequency of non-medication coping strategy use; further, as health fatalism increases, health-seeking behavior decreases, whereas the frequency of non-medication coping strategy use rises.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Development and Validation of Machine Learning Models for Risk Prediction of Postpartum Stress Urinary Incontinence: A Prospective Observational Study.

IF 1.8 3区医学

International Urogynecology Journal Pub Date : 2025-01-30 DOI: 10.1007/s00192-025-06057-6

Liyun Wang, Nana Wang, Minghui Zhang, Yujia Liu, Kaihui Sha

{"title":"Development and Validation of Machine Learning Models for Risk Prediction of Postpartum Stress Urinary Incontinence: A Prospective Observational Study.","authors":"Liyun Wang, Nana Wang, Minghui Zhang, Yujia Liu, Kaihui Sha","doi":"10.1007/s00192-025-06057-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06057-6","url":null,"abstract":"Introduction and hypothesis: This study aims to develop a postpartum stress urinary incontinence (PPSUI) risk prediction model based on an updated definition of PPSUI, using machine learning algorithms. The goal is to identify the best model for early clinical screening to improve screening accuracy and optimize clinical management strategies.Methods: This prospective study collected data from 1208 postpartum women, with the dataset randomly divided into training and testing sets (8:2). Five machine learning algorithms-logistic regression, decision trees, random forests, support vector machines (SVM), and eXtreme gradient boosting (XGBoost)-were used to construct the PPSUI risk prediction model. Model performance was evaluated using multiple metrics, and the best-performing model was selected and validated for generalizability with the testing set.Results: The final model retained ten features: birth weight, weight gain during pregnancy, BMI before delivery, pre-pregnancy BMI, age of delivery, gestation, parity, pre-delivery uterine height, age of first delivery, and labor analgesia. Among the five algorithms, the random forest model performed best, with a test AUC of 0.995 (95% CI 0.990-0.999, P < 0.05), accuracy of 0.956, precision of 0.957, recall of 0.944, specificity of 0.966, and F1 score of 0.951. The model's high generalizability was confirmed with the testing set and further validated through bootstrapping and tenfold cross-validation.Conclusion: The random forest model shows strong clinical potential for PPSUI risk prediction and early screening. Future studies should expand the sample size and include multi-center data to further enhance the model's clinical applicability.","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143065598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0