Comparing Post-Operative Pain Outcomes in Pelvic Organ Prolapse Surgery With and Without a Hysterectomy.

IF 1.8 3区 医学 Q3 OBSTETRICS & GYNECOLOGY
Wesley Nilsson, Elizabeth Narwold, Lindsay Turner, Jonathan Shepherd
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引用次数: 0

Abstract

Introduction and hypothesis: Many surgeons perform hysterectomy at the time of pelvic organ prolapse (POP) surgery if the uterus is present, but it is unknown how this impacts patient pain. The objective of this study was to compare POP surgeries with and without a hysterectomy for differences in post-operative pain using a visual analog scale (VAS), and morphine milligram equivalents (MME) at 24 h.

Methods: This was a secondary analysis of a randomized controlled trial comparing the impact of pre-operative intravenous acetaminophen with placebo on post-operative pain following POP surgery.

Results: We included 202 subjects undergoing minimally invasive POP surgery. A concomitant hysterectomy was performed in 120 of the subjects (59.4%). Most were white (97.5%), had baseline POP-Q stage III prolapse (75%), and BMI 27.8 ± 4.3 kg/m2, with no difference between groups. Those with concomitant hysterectomy were younger (64.2 ± 10.5 vs 67.5 ± 8.7 years, p = 0.02). Length of stay was 0.9 ± 0.5 days, and similar between groups (p = 0.24). Operative time was longer with concomitant hysterectomy (186.1 ± 52.7 vs 123.1 ± 47.2 min, p = 0.02). VAS scores 24 h post-operatively (hysterectomy = 3.0 ± 2.3, no hysterectomy = 2.7 ± 2.3, p = 0.49) and MMEs (51.4 ± 74.5 vs 37.1 ± 60.4, p = 0.15) were both similar. Patient-Reported Outcomes Measurement Information System scores measuring pain interference showed no difference between groups (22.9 ± 9.7 vs 20.9 ± 9.3, p = 0.21, possible range 8-40). Linear regression showed that concomitant hysterectomy did not impact 24-h VAS scores (adjusted beta = 0.113; p = 0.77) and showed no impact on 24-h MME (adjusted beta = 14.25; p = 0.15).

Conclusion: Although procedures were longer and patients were younger, with concomitant hysterectomy, there was no difference in 24-h VAS pain scores, 24-h MME opioid usage, or other pain metrics in POP surgeries with and without hysterectomy. Overall, opioid use and pain scores were low.

盆腔器官脱垂手术与不切除子宫术后疼痛结局的比较。
引言和假设:许多外科医生在盆腔器官脱垂(POP)手术时,如果子宫存在,会进行子宫切除术,但这对患者疼痛的影响尚不清楚。本研究的目的是通过视觉模拟量表(VAS)和24小时吗啡毫克当量(MME)比较有子宫切除和没有子宫切除的POP手术术后疼痛的差异。方法:这是一项随机对照试验的二次分析,比较术前静脉注射对乙酰氨基酚和安慰剂对POP手术后疼痛的影响。结果:我们纳入202例接受微创POP手术的患者。其中120例(59.4%)同时行子宫切除术。大多数为白色(97.5%),基线POP-Q III期脱垂(75%),BMI为27.8±4.3 kg/m2,组间无差异。合并子宫切除术的患者年龄较小(64.2±10.5岁vs 67.5±8.7岁,p = 0.02)。住院时间为0.9±0.5 d,两组间差异无统计学意义(p = 0.24)。合并子宫切除术的手术时间更长(186.1±52.7 vs 123.1±47.2 min, p = 0.02)。术后24 h VAS评分(切除子宫= 3.0±2.3,未切除子宫= 2.7±2.3,p = 0.49)与MMEs(51.4±74.5 vs 37.1±60.4,p = 0.15)相似。患者报告结果测量信息系统评分测量疼痛干扰,两组间无差异(22.9±9.7 vs 20.9±9.3,p = 0.21,可能范围8-40)。线性回归显示,合并子宫切除术不影响24小时VAS评分(校正β = 0.113;p = 0.77),对24小时MME无影响(校正β = 14.25;p = 0.15)。结论:虽然合并子宫切除术的手术时间更长,患者更年轻,但在有子宫切除术和没有子宫切除术的POP手术中,24小时VAS疼痛评分、24小时MME阿片类药物使用或其他疼痛指标没有差异。总体而言,阿片类药物使用和疼痛评分较低。
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来源期刊
CiteScore
3.80
自引率
22.20%
发文量
406
审稿时长
3-6 weeks
期刊介绍: The International Urogynecology Journal is the official journal of the International Urogynecological Association (IUGA).The International Urogynecology Journal has evolved in response to a perceived need amongst the clinicians, scientists, and researchers active in the field of urogynecology and pelvic floor disorders. Gynecologists, urologists, physiotherapists, nurses and basic scientists require regular means of communication within this field of pelvic floor dysfunction to express new ideas and research, and to review clinical practice in the diagnosis and treatment of women with disorders of the pelvic floor. This Journal has adopted the peer review process for all original contributions and will maintain high standards with regard to the research published therein. The clinical approach to urogynecology and pelvic floor disorders will be emphasized with each issue containing clinically relevant material that will be immediately applicable for clinical medicine. This publication covers all aspects of the field in an interdisciplinary fashion
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