International Urogynecology Journal最新文献

{"title":"Female Urinary Incontinence in Africa: Prevalence Estimates from a Systematic Review and Meta-Analysis.","authors":"Jeanne Bertuit, Andy-Muller Luzolo Nzinga, Véronique Feipel","doi":"10.1007/s00192-025-06146-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06146-6","url":null,"abstract":"<p><strong>Introduction: </strong>This systematic review and meta-analysis aimed to investigate the prevalence of urinary incontinence (UI) among women in African countries. Different types of UI, racial distributions, geographic locations, and methodological approaches were analyzed and compared.</p><p><strong>Methods: </strong>A systematic search was conducted using CINAHL, PubMed, Embase, and African Journals Online (AJOL). Studies published between 2000 and 2023 in French or English were included if they assessed the prevalence of UI among adult women (≥18 years) in Africa. A meta-analysis using a random-effects model was performed. The PRISMA checklist guided the reporting of this review.</p><p><strong>Results: </strong>A total of 22 studies were included. The pooled prevalence of UI was 24% (95% CI: 17-33%), with individual study estimates ranging from 2% to 80%. The pooled prevalence was 28% (95% CI: 19-38%) for urgency urinary incontinence (UUI), 35% (95% CI: 26-45%) for stress urinary incontinence (SUI), and 31% (95% CI: 18-45%) for mixed urinary incontinence (MUI). High heterogeneity was observed across studies (I² ranging from 72.6% to 99.8%; p 0.001 for Cochran's Q test in all UI subcategories).</p><p><strong>Conclusion: </strong>Urinary incontinence affects approximately one-quarter of adult women in Africa. However, the high heterogeneity in prevalence estimates-related to differences in methodology and UI definitions-limits the ability to draw firm conclusions.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186981","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feasibility and Safety of Same-Day Discharge After a Manchester Procedure.","authors":"Jozefien Hamilton, Joggem Veen, Anne Damoiseaux, Viviane Dietz, Jaklien Leemans, Sanne van Leijsen","doi":"10.1007/s00192-025-06177-z","DOIUrl":"https://doi.org/10.1007/s00192-025-06177-z","url":null,"abstract":"<p><strong>Introduction: </strong>With the implementation of the Enhanced Recovery After Surgery (ERAS) approach, the duration of hospital admission after vaginal prolapse surgery is reduced. In this study, we determined the safety and feasibility of same-day discharge in patients undergoing a Manchester procedure by comparing same-day discharge to overnight admission.</p><p><strong>Methods: </strong>This retrospective cohort study was performed in a teaching hospital in the Netherlands. During the period 2019-2023, all patients undergoing a Manchester procedure planned with overnight admission (group A) were compared to patients undergoing this surgery which was planned with same-day discharge (group B). The need for readmission and rate of prolonged hospitalization and complications were compared.</p><p><strong>Results: </strong>This study included 213 patients; 103 in group A and 110 in group B. Baseline characteristics were comparable between the two groups. The rate of readmission in both groups was similar (10.7% vs 15.5%; p = 0.183). No differences were found regarding complications such as discharge with prolonged catheterization due to urinary retention (15.5% vs 11.8%; p = 0.483).</p><p><strong>Conclusion: </strong>Performing the Manchester procedure with same-day discharge is safe and should be implemented as an important element of the ERAS approach. Same-day discharge further reduces length of hospital stay and could reduce costs, while promoting early patient mobilization.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Regulation of Autophagy by the Cdk1/p53/p21 Feedback Loop in an Interstitial Cystitis/Bladder Pain Syndrome Cell Model: Implications for Inflammatory Response.","authors":"Kun Wang, Jian Shi, Zhen Chen, Yibo Zhuang, Dong Xue","doi":"10.1007/s00192-025-06169-z","DOIUrl":"https://doi.org/10.1007/s00192-025-06169-z","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The Cdk1/p53/p21 feedback loop could play an important role in maintaining a consistently high urinary tract epithelial permeability. This study is aimed at elucidating whether this feedback loop is associated with the inadequate autophagic response and the heightened inflammatory response in interstitial cystitis/bladder pain syndrome (IC/BPS).</p><p><strong>Methods: </strong>To construct the IC/BPS cell model, HTB4 cells were first treated with 1% H₂O₂ for 1 h, followed by a 24-h exposure to TNFα (10 ng/ml). The protein expression levels of LC3-I/II and Beclin 1 were assessed using Western blot analysis. Autophagosome formation was visualized using monodansylcadaverine (MDC) staining. The secretion levels of inflammatory cytokines, including IL-6, IL-8, and TNFα, were quantified using enzyme-linked immunosorbent assay. Additionally, malondialdehyde (MDA) levels and the activities of antioxidant enzymes (GSH and SOD2) were measured.</p><p><strong>Results: </strong>Compared with normal urothelial HTB4 cells, the number of autophagosomes and the levels of LC3-I/II and Beclin 1 are significantly increased in IC/BPS cells. These cells also exhibit markedly higher levels of inflammatory markers (TNFα, IL-6, IL-8) and MDA, alongside notably reduced levels of the antioxidants GSH and SOD2. Compared with IC/BPS cells or IC/BPS cells co-transfected with p21 siRNA and Cdk1 control, the IC/BPS cells co-transfected with p21 siRNA and Cdk1 inhibitor exhibit a significant increase in terms of autophagosome numbers and the LC3-I/II level. Additionally, the levels of inflammatory factors are significantly decreased in the IC/BPS cells co-transfected with p21 siRNA and Cdk1 inhibitor.</p><p><strong>Conclusion: </strong>In IC/BPS, the Cdk1/p53/p21 feedback loop could regulate the level of autophagy and inflammatory response. This discovery identifies promising new therapeutic targets for IC/BPS, which may pave the way for innovative clinical approaches to this complex disorder.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Mirabegron and Propiverine Combination in the Treatment of Refractory Overactive Bladder.","authors":"Mehmet Gokhan Culha, Mehmet Ali Sezgin, Mustafa Erkoc, Eyyup Danis, Emre Can Polat, Alper Otunctemur","doi":"10.1007/s00192-025-06178-y","DOIUrl":"https://doi.org/10.1007/s00192-025-06178-y","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The aim of this study is to evaluate the effectiveness and safety of mirabegron + propiverine combination in the treatment of overactive bladder (OAB) resistant to anticholinergic agent or beta-3 agonist treatment.</p><p><strong>Method: </strong>Patients who presented with OAB symptoms between March 2019 and August 2023 and did not respond to anticholinergic or beta-3 agonist treatment were included in the study. All patients were recommended to use mirabegron 50 mg (Betmiga, Astellas Pharma, Japan) and propiverine 30 mg (Mictonorm SR, 30 mg, Recordati Pharmaceuticals, Italy) once a day. Patients' symptoms were evaluated with OABSS and bladder diary 3 months after treatment. Side effects and satisfaction rates were recorded.</p><p><strong>Results: </strong>A total of 320 patients were included in the study. One-year data of a total of 264 patients were examined. After 1 year of treatment, the patients' OABSS score, mean daily micturition frequency according to the bladder diary, frequency of urge incontinence, nocturia, and number of pads decreased compared to before treatment (p < 0.001 for each). After 1 year, 62.1% (164/264) of patients benefited from the mirabegron + propiverine combination. The most common side effects were dry mouth in 43 patients (16.3%) and constipation in 59 patients (22.3%).</p><p><strong>Conclusion: </strong>Mirabegron + propiverine treatment is an effective and reliable treatment option in the treatment of OAB resistant to medical monotherapy. With this combination treatment to be used before botulinum toxin application in the treatment of resistant OAB, the number of patients who will receive Botox may decrease.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative Ultrasound Predictors of Treatment Failure after 24 Months of Transobturator Midurethral Sling.","authors":"Enrique González-Díaz, Ana Victoria Martin Corral","doi":"10.1007/s00192-025-06179-x","DOIUrl":"https://doi.org/10.1007/s00192-025-06179-x","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>To evaluate the role of pelvic floor ultrasound (PF-US) in predicting persistent urinary incontinence after tension-free vaginal obturator tape (TVT-O) placement surgery and to identify prognostic ultrasound parameters.</p><p><strong>Methods: </strong>We performed a retrospective analysis of 74 patients who underwent TVT-O placement for stress urinary incontinence (UI) or stress-predominant mixed UI. Preoperative assessment included clinical evaluation, urinary diary, validated questionnaires, and PF-US to measure bladder neck mobility and descent, presence of urethral funneling, urethral length, and bladder wall thickness (BWT). Surgical success was defined as resolution of incontinence at 24 months postoperatively.</p><p><strong>Results: </strong>At 24 months, 19% of patients presented with persistent incontinence. Preoperative factors associated with surgical failure were age, body mass index, BWT at dome, anterior wall and average BWT, urethral length and urethral funneling. In multivariate logistic regression analysis, only preoperative ultrasound findings were associated with UI persistence, including the presence of urethral funneling, a BWT greater than 7 mm at the dome of the bladder, and a urethral length longer than 45 mm.</p><p><strong>Conclusion: </strong>Preoperative ultrasound is a valuable tool to predict functional outcomes of TVT-O surgery. Preoperative assessment of urethral funneling, BWT at dome and urethral length may help identify patients at higher risk of surgical failure with persistent incontinence. Integration of ultrasound into routine evaluation could improve patient selection and surgical planning.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Vaginal Laser Treatment on Stress Urinary Incontinence: A Randomized Controlled Trial.","authors":"Lok Wun Yim, Osanna Yee Ki Wan, Daniel Wong, Man Sum Tam, Yun Ting Lee, Kai Wan Lee, Kwong Wai Choy, Symphorosa Shing Chee Chan, Rachel Yau Kar Cheung","doi":"10.1007/s00192-025-06160-8","DOIUrl":"https://doi.org/10.1007/s00192-025-06160-8","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This study evaluates the efficacy of vaginal Erbium:YAG laser treatment for stress urinary incontinence (SUI) compared with sham treatment over 12 months.</p><p><strong>Methods: </strong>This single-blinded, multicenter randomized controlled trial involved women diagnosed with urodynamic SUI at three urogynecology centers in Hong Kong. Participants were randomly assigned to receive either vaginal laser therapy (two sessions, 4 weeks apart) or sham treatment. The primary outcome was the reduction in Pelvic Floor Distress Inventory (PFDI) Urinary Distress Inventory (UDI) Stress subscale scores at 6 and 12 months. Secondary outcomes included urinary incontinence episodes, severity from bladder diaries, visual analog scale (VAS) scores, and scores from the Pelvic Floor Impact Questionnaire Urinary Impact Questionnaire and the International Consultation on Incontinence Questionnaire Urinary Incontinence Short Form.</p><p><strong>Results: </strong>Out of 114 screened women, 75 were randomized. Significant reductions in PFDI UDI stress subscale scores were shown in the treatment group at the 6-month and 12-month follow-up (p < 0.001 at 6 months; p < 0.001 at 12 months) but was not significant in the control group. Significant reductions were observed in the treatment group at the 6-month and 12-month follow-up in all secondary outcome parameters whereas the Pelvic Floor Impact Questionnaire UDI score and the VAS score of SUI severity at both 6 months and 12 months were not significantly reduced in the control group. There was no significant difference in both primary or secondary outcomes between groups.</p><p><strong>Conclusions: </strong>Vaginal Erbium: YAG laser improved SUI symptoms and shows potential as a minimally invasive option, but lacks significant differences from sham treatment, necessitating further research.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of a Complex Intervention for the Management of Urinary Incontinence Among Community-Dwelling Older Women.","authors":"Wenqi Liu, Xuemei Sun, Yinyan Gao, Jinlu Song, Wenjie Dai, Irene X Y Wu","doi":"10.1007/s00192-025-06159-1","DOIUrl":"https://doi.org/10.1007/s00192-025-06159-1","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This study is aimed at developing a complex intervention that considers stakeholders' needs and preferences, as well as facilitators and barriers affecting adherence to interventions for the management of urinary incontinence among community-dwelling older women.</p><p><strong>Methods: </strong>Following the Medical Research Council framework for developing complex interventions, this study includes two steps. In step 1, guided by the Evidence to Decision framework, qualitative interviews were conducted with stakeholders (older women with urinary incontinence and community doctors) to find out their needs and preferences regarding the intervention, as well as to identify key factors influencing the intervention adherence. In step 2, an initial draft of the complex intervention was constructed based on the information generated from the qualitative interviews. Further refinements were made through expert consultations before a final version was reached.</p><p><strong>Results: </strong>A total of 13 older women with urinary incontinence and 14 community doctors were interviewed in the first step. Stakeholders preferred a combination of group-based pelvic floor muscle training in community activity rooms and self-directed home pelvic floor muscle training, with a frequency of 2-3 times per week. Five facilitators and five barriers affecting adherence to the intervention among community-dwelling older women with urinary incontinence were identified, and coping measures were proposed accordingly.</p><p><strong>Conclusions: </strong>A tailored complex intervention was developed, including a core component (pelvic floor muscle training), along with six supplementary components (physical assessment, health education, reminders and supervision, group discussion, reward system, and flexible schedule).</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110606","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Clinical Outcomes on Short Tape Single-Incision Sling Devices (Solyx) and Adjustable Length Device (I-Stop-Mini) for Urodynamic Stress Incontinence at 1 Year.","authors":"Tsia-Shu Lo, Louiza Erika Rellora, Eyal Rom, Chia-Hsuan Yang, Huan-Ka Chiung","doi":"10.1007/s00192-025-06155-5","DOIUrl":"https://doi.org/10.1007/s00192-025-06155-5","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The study is primarily aimed at comparing the outcome of voiding dysfunction related to over-tension and the resumption of normal voiding after tension-releasing suture (TRS) manipulation following Solyx and I-stop-mini procedures. Second, it is aimed at determining the cure rate, complications, and quality of life at 1 year postoperatively.</p><p><strong>Methods: </strong>This is a retrospective study conducted from March 2015 to June 2023. Patients with clinically confirmed pure stress urinary incontinence (SUI) and urodynamic stress incontinence were included; those with pelvic organ prolapse (POP) greater than stage II, neurogenic lower urinary tract dysfunction, or post-void residual of more than 100 ml were excluded. Standardized preoperative evaluations and TRS were used. Follow-ups were conducted at 1 week, 1 month, 3 months, 6 months, and annually. Statistical analyses were performed using SPSS version 17.</p><p><strong>Results: </strong>Out of 453 patients, 333 underwent Solyx and 120 underwent I-stop-mini procedures. The mean age was 56.6 years with an average BMI of 25.4. After Solyx, 18.9% had urinary retention whereas 10.8% had urinary retention after I-stop-mini. TRS manipulation was done in 12% post-Solyx and 4.2% post-I-stop-mini. Objective cure rates were 87.1% for Solyx and 91.7% for the I-stop-mini, with no statistical difference. Two patients in the Solyx group required repeat mid-urethral sling surgery. No cases of mesh erosion were noted in either of the groups.</p><p><strong>Conclusions: </strong>Solyx and I-stop-mini are both effective at treating SUI. A short-tape single-incision sling device (Solyx) resulted in more voiding dysfunction than the adjustable-length device (I-stop-mini). TRS helps to resolve postoperative voiding dysfunction.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor \"Joint Terminology Report: Terminology Standardization for Female Bladder Pain Syndrome\".","authors":"Beth Shelly, Melanie Morin, Helena Frawley","doi":"10.1007/s00192-025-06168-0","DOIUrl":"https://doi.org/10.1007/s00192-025-06168-0","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144085989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Decade-Old Giant Urinoma Following Ureteric Injury.","authors":"Deeksha Pandey, Vinu Gopinath, Sirisha V, Alla Mounika, Pranadeep Reddy Inukollu, Lilarani Vijayaraghavan, Rema V Nair","doi":"10.1007/s00192-025-06152-8","DOIUrl":"https://doi.org/10.1007/s00192-025-06152-8","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Urinoma, a collection of urine outside the urinary tract, is an uncommon entity typically associated with trauma, obstruction, or iatrogenic injury. We report a case of a giant urinoma in a 55-year-old woman that posed a diagnostic challenge until surgical exploration. She presented with progressive abdominal distension and nonspecific pain 10 years following a left ovariotomy. Initial clinical evaluation and imaging suggested a large intra-abdominal mass with characteristics mimicking a cystic neoplasm. Despite extensive diagnostic workup, including ultrasonography, contrast-enhanced CT and MR, the precise diagnosis remained elusive.</p><p><strong>Methods: </strong>Given the diagnostic uncertainty and worsening symptoms, surgical exploration was undertaken. Intraoperatively, a massive urinoma, measuring approximately 25 cm in diameter, was identified. Exploration of the cyst revealed an opening traced to the left ureter. The urinoma was drained, the cyst wall excised and definitive ureteric repair was performed successfully.</p><p><strong>Results: </strong>Histology confirmed the diagnosis of urinoma.</p><p><strong>Conclusion: </strong>This case highlights the diagnostic challenges posed by giant urinomas, particularly when the presentation is atypical and imaging is equivocal. It underscores the importance of considering delayed complications from prior pelvic surgeries and the critical role of surgical exploration in resolving diagnostic dilemmas.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-05-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}