Angie Rantell, Zeelha Abdool, Morgan E Fullerton, Abel Gedefaw, Kate Lough, Pawel Miotla, Narmin Mukhtarova, Patricia Neumann, Jordan Spencer, Kristina J Warner, Heidi W Brown
{"title":"International Urogynecology Consultation Chapter 3 Committee 1 - Pessary Management.","authors":"Angie Rantell, Zeelha Abdool, Morgan E Fullerton, Abel Gedefaw, Kate Lough, Pawel Miotla, Narmin Mukhtarova, Patricia Neumann, Jordan Spencer, Kristina J Warner, Heidi W Brown","doi":"10.1007/s00192-024-06020-x","DOIUrl":"https://doi.org/10.1007/s00192-024-06020-x","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This manuscript is part of the International Urogynecological Consultation (IUC) on Pelvic Organ Prolapse (POP), Chapter 3, Committee 1 focusing on pessary management of POP.</p><p><strong>Methods: </strong>A narrative review was conducted by an international, multi-disciplinary group of clinicians working in the field of pelvic health following a search of the literature using the MeSH terms \"pelvic organ prolapse\" OR \"urogenital prolapse\" OR \"vaginal prolapse\" OR \"uterovaginal prolapse\" AND \"pessary\" OR \"support device\" OR \"intravaginal device.\" Relevant studies, as determined after review using the Covidence manuscript review platform, were included.</p><p><strong>Results: </strong>A total of 540 articles were reviewed, of which 313 were included for this narrative review. The reported pessary fitting success rate ranges from 41% to 96.6%, and the continuation of successful use rate varied from 21% to 97.7%. The most likely predictors of unsuccessful fitting trials were previous POP surgery, previous hysterectomy, short vaginal length, wide genital hiatus, and posterior compartment involvement. Following successful pessary placement in individuals with POP, vaginal bulge and pressure resolved in over 90%. A significant improvement in obstructive voiding was reported in 40-97% of participants, urinary urgency in 38%, urgency urinary incontinence in 29-77%, and stress urinary incontinence in 9-45%. Older age and women who can self-manage the pessary care or had family support were factors associated with pessary continuation. Common reasons reported for discontinuation included expulsion, vaginal pain/discomfort, unwillingness to continue, erosions, desire for surgery, bleeding, symptoms not improved with pessary, and incontinence. More serious complications (fistula, bowel obstruction, pessary impaction, and vaginal cancer) are rare, and occur usually in older women in whom pessary maintenance has been neglected. There is no high-quality evidence to guide pessary choice. The current literature lacks studies specifically focused on determining the role of preventative measures, i.e., estrogen, pessary type/material as regards to pessary-associated complications (PACs). The review identified a lack of information about the relevant and required training and education (for healthcare professionals and patients) for pessary provision, use, and management.</p><p><strong>Conclusions: </strong>There is a considerable body of published work on the use of pessaries for POP, including effectiveness, factors associated with success and failure, and complications. However, there is a dearth of published literature regarding how pessary types are selected by providers, how providers are trained, what defines competency in pessary provision, and what constitutes appropriate patient education related to pessary use and management.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Incorporating Perineorrhaphy into the LeFort Colpocleisis: A Modified Surgical Approach.","authors":"Savci Bekir Telek, Brad St Martin, Oz Harmanli","doi":"10.1007/s00192-025-06041-0","DOIUrl":"https://doi.org/10.1007/s00192-025-06041-0","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Perineorrhaphy with levator myorrhaphy is considered a standard part of colpocleisis. Typically, this is done through a separate incision after colpocleisis is completed. We present a video to demonstrate a modified approach to LeFort colpocleisis incorporating perineorrhaphy into the procedure.</p><p><strong>Methods: </strong>A rectangular piece of anterior vaginal mucosa is dissected off the underlying fibromuscular tissue starting from 2-3 cm distal to the cervix and ending proximal to the urethrovesical junction. Similarly, a symmetrical posterior vaginal mucosa is dissected starting from the introitus and ending 2-3 cm distal to the cervix. The lateral edges of the rectangles between the anterior and posterior vaginal walls are sutured to create channels. The raw surfaces, including the fibromuscular tissue on the anterior and posterior vagina, are sutured to each other in three rows. Vaginal epithelium is closed continuously starting from the anterior wall and ending with posterior epithelium at the introitus.</p><p><strong>Results: </strong>Dissection of the anterior and posterior vaginal epithelium mimics standard colporrhaphy. The number of incisions and suturing is decreased by incorporating perineorrhaphy into colpocleisis. Sagittal closure with this technique restores the Aa point to a more anatomical position.</p><p><strong>Conclusion: </strong>These modifications may decrease operative time and de novo stress incontinence and allow less experienced surgeons to consider colpocleisis. Our surgical approach, which incorporates perineorrhaphy into colpocleisis, enables easier adaptation to the procedure and may decrease de novo stress incontinence.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Laparoscopic Pudendal Nerve Release at the Level of Sacrospinous Ligament.","authors":"Baris Mulayim, Sema Mulayim","doi":"10.1007/s00192-025-06062-9","DOIUrl":"https://doi.org/10.1007/s00192-025-06062-9","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Pudendal nerve release can be managed by the laparoscopic approach for pudendal nerve entrapment.</p><p><strong>Methods: </strong>This is a case report of a stepwise demonstration of the technique with narrated video footage. A 71-year-old woman, gravid 7, parity 3, abortion 4, live births 3 vaginal delivery, complained of pain while sitting. She had been having vaginal and vulvar pain on the left side for 3 years. At vaginal examination, she had pain over the sacrospinous ligament with palpation. Tinel's sign (+) on the left side. Left side pudendal nerve block relieves pain for 1 h. Using a laparoscopic approach for a left pudendal nerve release at the level of sacrospinous ligament, the dissection started at the level of medial to the infundibulopelvic ligament, after visualization of obliterated umbilical artery and obturator nerve and vessels, dissection continued deeper to the pelvic floor visualizing the obturator internus muscle, then pudendal nerve and vessels are identified and the coccygeus muscle and sacrospinous ligament are observed. The sacrospinous ligament is cut all the way to the entrance of Alcock's canal.</p><p><strong>Results: </strong>The operation was finished without any complication and the patient was discharged after the operation day. Pain decreased on her postoperative examination. Follow-up visits will be continued at 3 and 6 months.</p><p><strong>Conclusions: </strong>Laparoscopic pudendal nerve release is reproducible, effective, safe, and has a steep learning curve method for the management of pudendal nerve entrapment.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143033126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qihuang Liu, YouJun Zhou, Liping Tan, Yan Chen, Xingnan Zhou, Juan Liu
{"title":"Autophagy Attenuates Oxidative Stress-Induced Collagen Degradation in Vaginal Fibroblasts: Implications for Pelvic Organ Prolapse.","authors":"Qihuang Liu, YouJun Zhou, Liping Tan, Yan Chen, Xingnan Zhou, Juan Liu","doi":"10.1007/s00192-024-06031-8","DOIUrl":"https://doi.org/10.1007/s00192-024-06031-8","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The relationship between autophagy and pelvic organ prolapse (POP) remains unknown. The aim of this novel experimental study, utilizing tissue samples derived from women undergoing gynecological surgery, is to investigate the role of autophagy in mitigating collagen degradation in human vaginal fibroblasts induced by oxidative stress, with particular emphasis on its implications in the pathogenesis of POP. Exploring the role of autophagy in protecting against collagen degradation and cellular senescence in human vaginal fibroblasts under oxidative stress may offer new insights into therapeutic strategies for conditions such as POP.</p><p><strong>Methods: </strong>This study consists of laboratory-based experimental research that utilizes tissue samples collected from female patients undergoing gynecological surgery to analyze the role of autophagy in collagen degradation induced by oxidative stress. By treating with different concentrations of hydrogen peroxide (H<sub>2</sub>O<sub>2</sub>) and using rapamycin (RAPA) and 3-methyladenine (3-MA) as autophagy activators and inhibitors respectively, the effects on human vaginal fibroblasts (HVFs) were evaluated. Cell viability was determined using the Cell Counting Kit-8 test. Cellular senescence was determined with senescence-associated-β-galactosidase labeling and western blotting to identify the expression of p21 and p53. Reactive oxygen species (ROS) were determined with 2,7-dichlorofluorescin diacetate. Additionally, western blotting was used to establish collagen I, collagen III, microtubule-associated protein 1A/1B-light chain 3 (LC3), Beclin-1, and p62 and reverse transcription-quantitative polymerase chain reaction was used to determine the mRNA levels of COL3A1, COL1A1, TIMP1, MMP9, LC3, and Beclin-1 to investigate collagen metabolism and autophagic activity.</p><p><strong>Results: </strong>The results showed that high-dose H<sub>2</sub>O<sub>2</sub> significantly increased ROS levels, cell senescence, and collagen degradation in HVFs. The combined use of RAPA significantly reduced ROS levels, collagen degradation, and cell senescence, but this protective effect disappeared when 3-MA was added. Nevertheless, co-treatment of HVFs with RAPA, H<sub>2</sub>O<sub>2</sub>, and 3-MA abolished the positive impact of RAPA via boosting autophagy resistance.</p><p><strong>Conclusions: </strong>Autophagy inhibits collagen degeneration and cellular senescence caused by oxidative stress.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge, Attitude, and Practice Toward Pelvic Floor Dysfunction Among Postpartum and Postmenopausal Women: A Cross-sectional Study.","authors":"Jing Lin, Bin Yu, Yong He, Ni Tang, Qianying He","doi":"10.1007/s00192-025-06043-y","DOIUrl":"https://doi.org/10.1007/s00192-025-06043-y","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This research sought to explore the knowledge, attitude, and practice (KAP) toward pelvic floor dysfunction (PFD) among postpartum and postmenopausal women.</p><p><strong>Methods: </strong>This cross-sectional study was performed among postpartum and postmenopausal women between May and August 2023. Demographic data, along with KAP scores, were collected using a self-designed questionnaire-based approach.</p><p><strong>Results: </strong>Six hundred seventy-seven valid questionnaires were collected and analyzed, with 206 (30.43%) participants aged under 30 years old. The mean scores of knowledge, attitude, and practice dimension were 7.1 ± 2.42 (range 0-9), 33.42 ± 4.75 (range 8-40), and 24.69 ± 6.68 (range 7-35). Proactive practice was independently associated with knowledge scores (OR 1.150, 95%CI 1.059-1.249, P = 0.001), attitude scores (OR 1.125, 95%CI 1.081-1.171, P < 0.001), age 30 years or older (OR 2.326, 95%CI 1.555-3.481, P < 0.001), and being in a postpartum state (OR 0.542, 95%CI 0.325-0.903, P = 0.019). The structured equation model revealed that knowledge exerted a strong positive direct effect on attitude (β = 0.634, P < 0.001), attitude had a significant direct effect on practice (β = 0.681, P < 0.001), and knowledge also markedly influenced practice (β = 0.907, P < 0.001).</p><p><strong>Conclusion: </strong>Postpartum and postmenopausal women demonstrated adequate knowledge, positive attitudes, and proactive practices regarding PFD. It emphasizes the significance of tailored education, a holistic approach, and behavioral interventions to improve clinical practice in pelvic floor health.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Reut Rotem, Yara Alkeesh, Ayala Hirsch, Inbar Ben-Shachar, Naama Marcus
{"title":"Long-term Outcomes of Laparoscopic Sacrohysteropexy with SERATEX<sup>®</sup> SlimSling<sup>®</sup> Mesh: A Retrospective Case Series.","authors":"Reut Rotem, Yara Alkeesh, Ayala Hirsch, Inbar Ben-Shachar, Naama Marcus","doi":"10.1007/s00192-024-06037-2","DOIUrl":"https://doi.org/10.1007/s00192-024-06037-2","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Pelvic organ prolapse (POP) surgery has evolved toward minimally invasive techniques. Laparoscopic sacrohysteropexy (LSHP) is associated with reduced morbidity and lower mesh exposure risks. This study evaluates the long-term outcomes of LSHP using the SERATEX<sup>®</sup> SlimSling<sup>®</sup> mesh for isolated uterine prolapse.</p><p><strong>Methods: </strong>A retrospective case series was conducted on patients who underwent LSHP with SERATEX<sup>®</sup> SlimSling<sup>®</sup> mesh for apical prolapse with uterine preservation between 2014 and 2020. Data were extracted from medical records, including demographics, intraoperative details, and postoperative outcomes. Modified POP-Q measurements (Ba, Bp, C, D) were recorded. Patients were assessed perioperatively and at multiple postoperative intervals, with follow-up via telephone interviews by a urogynecologist. Statistical analysis included descriptive statistics and univariate analysis, with a p value of less than 0.05 considered significant.</p><p><strong>Results: </strong>Twenty-five women underwent LSHP with a mean age of 46 years. Most patients had isolated apical prolapse without other symptoms. Intraoperatively, 75% had concomitant cervical shortening, 10% had anterior colporrhaphy, and 30% had mid urethral sling, with a mean surgery duration of 112 min and no postoperative complications. Median follow-up was 66 months. Three patients (12%) experienced prolapse recurrence, mainly cystocele with two requiring reoperations. Four patients conceived and delivered post-procedure, all via cesarean section. At the long-term telephone interview, 76.2% were very happy with the surgery, 14.3% happy, and 9.5% unhappy.</p><p><strong>Conclusions: </strong>LSHP with the SERATEX<sup>®</sup> SlimSling<sup>®</sup> mesh for isolated uterine prolapse demonstrates a fair safety profile, durable outcomes, high patient satisfaction, and favorable pregnancy outcomes. This procedure offers a viable, minimally invasive option for uterine preservation.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Tribute to the Past, A Warm Welcome to the Future: Acknowledging Our Associate Editors.","authors":"Maria A T Bortolini, Kaven Baessler","doi":"10.1007/s00192-025-06067-4","DOIUrl":"https://doi.org/10.1007/s00192-025-06067-4","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anastasiya Holubyeva, Kaythi Khin, Tess Gao, Shaun Adair, Erika Wasenda, Laura Dhariwal, Ricardo Caraballo, Svjetlana Lozo, John Rutledge, Carolyn Botros
{"title":"Onabotulinum Toxin A-Led Urinary Tract Infections-Should we Safeguard? A Randomized Controlled Trial.","authors":"Anastasiya Holubyeva, Kaythi Khin, Tess Gao, Shaun Adair, Erika Wasenda, Laura Dhariwal, Ricardo Caraballo, Svjetlana Lozo, John Rutledge, Carolyn Botros","doi":"10.1007/s00192-024-06028-3","DOIUrl":"https://doi.org/10.1007/s00192-024-06028-3","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The objective of our study was to evaluate the need for antibiotic prophylaxis for urinary tract infection (UTI) prevention before Onabotulinum toxin A injection for overactive bladder (OAB). We hypothesize that the lack of antibiotic prophylaxis might not be inferior to administering prophylaxis.</p><p><strong>Methods: </strong>This was a multi-centered, nonblinded, randomized controlled trial conducted between August 2022 and September 2024. Participants were randomized to either receive oral antibiotics or no treatment. Our primary outcome was to measure the rate of UTI at 2 weeks. Our secondary outcomes included post-void residuals, assessment for antibiotic compliance, and UTI rates at 6 weeks. Given a 20% UTI rate and a delta of 20%, 64 participants per study arm were necessary to achieve 80% power with an alpha value of 0.05.</p><p><strong>Results: </strong>Rates of UTI at 2 weeks post-procedure were 9.2% in the antibiotics group and 10.9% in the control group (p = 0.75). UTI rates 6 weeks post-procedure were 4.7% in the antibiotics group and 11.1% in the control group (p = 0.21). When analyzing variables such as age, race, body mass index, menopause status, vaginal estrogen use, or the rates of positive pre-procedure urine cultures, no factors proved to be predictors of developing a UTI at 2 weeks post-procedure. The urinary retention rate in our study was 0.8%.</p><p><strong>Conclusions: </strong>Rates of UTI were not significantly different between patients who obtained antibiotics prophylaxis and those who did not at 2 and 6 weeks following injection. Foregoing antibiotics prophylaxis in order to safeguard from the dangers of antimicrobial resistance may be considered in the treatment of OAB with Onabotulinum toxin A.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Global Trends in Prevalence and Future Projections of Pelvic Organ Prolapse: A 30-year Epidemiological Study.","authors":"Peipei Li, Hongyun Ma, Jiao Zhang, Qiaorui Zhang","doi":"10.1007/s00192-025-06049-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06049-6","url":null,"abstract":"<p><strong>Introduction: </strong>Pelvic organ prolapse (POP) is a widespread disease in women. Despite its significant prevalence, there is a lack of comprehensive global studies, emphasizing the urgent need for tailored prevention and treatment approaches. This study aims to examine the global burden of POP from 1990 to 2021 and project future trends using the GBD data.</p><p><strong>Methods: </strong>Data were collected from the GBD 2021 database. A Bayesian age-period-cohort (BAPC) model was used to analyze the trends and predict future burden, with age-standardized prevalence rate (ASPR) and years lived with disability (YLD) as key metrics.</p><p><strong>Results: </strong>In 2021, the global ASPR and age-standardized YLD rate of POP were 2769.4 (95% UI 2299.2-3298.2) and 8.5 (95% UI 4.1-16.2) per 100,000 people, respectively. Both ASPR and YLD rate decreased between 1990 and 2021. The burden of POP is highest in low-SDI regions. The global prevalence of POP was highest in the 80+ age group, while the absolute number of cases reached its peak in the 55-59 age group. By 2036, the global population of POP patients will reach 156 million. Additionally, both the ASPR and AS-YLD rates of POP will continue to decline over the next 15 years.</p><p><strong>Conclusion: </strong>While the global burden of POP decreased between 1990 and 2021, ASPRs in regions with low SDI remained high. With the gradual aging population, POP will continue to pose a significant burden on women's health and the social economy in the future. Strengthening global surveillance and prevention efforts for POP remains a critical challenge.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Measurement of the Vaginal Pressure Profile with the Femfit® and Leakage Events Using a Newly Developed Pad Test during Selected Sports Activities: A Pilot Study.","authors":"Magdaléna Hagovská, Alena Bukova, Jan Svihra","doi":"10.1007/s00192-025-06051-y","DOIUrl":"https://doi.org/10.1007/s00192-025-06051-y","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Measuring changes in the vaginal pressure profile (VPP) with the Femfit® by JUNOFEM during various sports will help improve understanding of the magnitude of pressures generated during such activities and the pelvic floor's response to those pressures. This could aid in selecting safe exercises for women with pelvic floor dysfunction. The primary aim of this study was to measure intravaginal pressure changes using a novel pressure sensor array (Femfit®) during high-risk sports activities in elite female athletes with and without stress urinary incontinence (SUI). The secondary aim was to quantify the amount of urine leakage during these activities using a newly developed innovative pad weighing test (iPWT).</p><p><strong>Methods: </strong>We used the International Consultation on Incontinence Questionnaire-Urinary Incontinence Short Form (ICIQ-UI SF) to assess participants and measured the VPP using the Femfit® device during ground jumps, trampoline jumps, weightlifting, slow running and fast running. Urine leakage was assessed using the iPWT during the five sports activities.</p><p><strong>Results: </strong>The highest VPP (53.7 ± 21.6 mmHg) was recorded during ground jumps, followed by trampoline jumps. The second-highest values (24.7 ± 8.1 mmHg) were measured during fast and slow running, while the lowest values were observed during weightlifting (11.6 ± 4.0 mmHg). Measurements of VPP during sporting activities revealed lower pressure values in elite female athletes with SUI than in those without SUI. The overall mean urine leakage in the SUI group during the five activities was 6.6 ± 1.8 g.</p><p><strong>Conclusion: </strong>On the basis of the VPP and the newly developed iPWT, sports involving jumps and lunges have been identified as revealing SUI and should therefore be included in testing female athletes. The iPWT may prove suitable for measuring SUI in elite female athletes but requires further testing and validation.</p><p><strong>Clinicaltrials: </strong>gov Registration: NCT06224335.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-01-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}