International Urogynecology Journal最新文献

{"title":"Comment on \"Platelet-Rich Plasma and Fractional CO₂ Laser Therapy to Reduce Surgical Intervention for Symptomatic Vaginal Mesh-Related Complications\".","authors":"Kubilay Sarikaya","doi":"10.1007/s00192-025-06170-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06170-6","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pelvic Organ Prolapse Quantification After Pessary Removal: The Use of Upright MRI in POP Research.","authors":"Annemarie van der Steen, Frank F J Simonis, Anique T M Grob","doi":"10.1007/s00192-025-06182-2","DOIUrl":"https://doi.org/10.1007/s00192-025-06182-2","url":null,"abstract":"<p><strong>Introduction: </strong>When pelvic organ prolapse (POP) patients change from pessary to surgical treatment, new POP quantification is often necessary. However, the time to maximal POP recurrence after pessary removal is unclear. This video-article illustrates the variation over time of POP extent after pessary removal.</p><p><strong>Methods: </strong>Upright MRI scans of 12 POP patients were used to measure the distances from the lowest points of bladder and cervix to the Pelvic Inclination Correction System (PICS)) line, with the pessary in situ, immediately, 4 and 8 h after pessary removal. Statistical differences between time points were determined.</p><p><strong>Results: </strong>The bladder descended immediately after pessary removal from a median of 0.1 cm above to 1.8 cm below the PICS line. In 58% of patients, the bladder then remained stable; in 33%, the bladder further descended up to 5.4 cm after 4 to 8 h. The cervix descended immediately after pessary removal from a median of 3.1 cm to 1.9 cm above the PICS line. In 17% of patients, a late cervix descent after 4-8 h was seen.</p><p><strong>Conclusion: </strong>POP quantification should be delayed at least 8 h after pessary removal to prevent underestimation of POP extent.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144215793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Dutch Translation, Cultural Adaption, and Validation of the German Pelvic Floor Questionnaire for Pregnant and Postpartum Women.","authors":"Linde M L Titulaer, Viola C Sandfort, Lidwine B Mokkink, Annelies L Pool-Goudzwaard, Marco H Blanker, Gert-Jan van Baaren, Anna E Seijmonsbergen-Schermers, Jan-Paul W R Roovers, Corine J M Verhoeven","doi":"10.1007/s00192-025-06173-3","DOIUrl":"https://doi.org/10.1007/s00192-025-06173-3","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Pregnancy and childbirth are important risk factors for developing pelvic floor dysfunction (PFD). A valid and reliable screening instrument is essential for timely identification and treatment of PFD. The German Pelvic Floor Questionnaire for Pregnant and Postpartum women (PFQ-PP) assesses symptoms, severity, and impact on quality of life for the bladder function, bowel function, prolapse, and sexual health domain. However, no similar questionnaire exists in Dutch. This study was aimed at translating, culturally adapting, and validating the German PFQ-PP for use in the Netherlands, resulting in the Dutch PFQ-PP.</p><p><strong>Methods: </strong>A forward-backward translation method was used to translate and cross-culturally adapt the German PFQ-PP. Content validity was assessed by an expert committee of seven health care professionals who reviewed the translated version, and by using semi-structured cognitive interviews with four pregnant and five postpartum women. For field testing, 202 pregnant and postpartum women completed the questionnaire twice, with a 1-week interval to assess test-retest reliability, measurement error, and known group validity.</p><p><strong>Results: </strong>The Dutch PFQ-PP demonstrated good content validity both in health care professionals and in pregnant and postpartum women. Intraclass correlation coefficients ranged from 0.82 to 0.92. Standard errors of measurement ranged from 0.38 to 0.60 for the four domains (all domain scores ranging from 0 to 10). The questionnaire discriminated as expected between women suffering from symptoms and those who do not.</p><p><strong>Conclusions: </strong>The Dutch PFQ-PP is valid and reliable in assessing bladder function, bowel function, prolapse, and sexual health in pregnant and postpartum women.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144208463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the Efficacy and Safety of Hyaluronic Acid Injection for Volume Restoration of the Labia Majora: ESOLANE study.","authors":"Fabien Boucher, Catherine Eychenne, Brice Gurriet, Nicolas Berreni, Juan Berrocal, Phryné Foulc, Alain Levy, Adriana Guzman-Ruiz, Barbara Hersant","doi":"10.1007/s00192-025-06094-1","DOIUrl":"10.1007/s00192-025-06094-1","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Labia majora atrophy and protrusion of the labia minora beyond the labia majora is a concern for an increasing number of women who consider it aesthetically and, sometimes, functionally unsatisfactory. The ESOLANE study was a multicenter clinical investigation designed to collect effectiveness and safety data on DESIRIAL® PLUS injected subcutaneously in the labia majora in participants seeking labia majora volume deficits correction.</p><p><strong>Methods: </strong>A prospective, uncontrolled, open-label multicenter study was conducted between November 2019 and December 2021. Seventy-three women with labia majora hypotrophy or atrophy and requesting labia majora volume restoration were enrolled and 72 were treated. Outcome measures were collected at baseline, then 4, 12, 24, 36, and 52 weeks post treatment. Primary endpoint was the proportion of patients' who reported aesthetic improvement on the global aesthetic improvement scale (GAIS) 12 weeks after initial injection. Secondary endpoints were assessments of patients' and investigators' who reported GAIS, patient sexual function and physical symptoms, patient satisfaction, and safety.</p><p><strong>Results: </strong>According to the patients' who reported GAIS, 97% rated themselves as improved 12 weeks following the initial treatment. Improvement levels were high throughout the 52-week follow-up period with rates > 92%. Improvements were also confirmed on investigators' assessments with rates > 86%. Furthermore, patients reported significantly improved sexual function, symptom reduction, and high satisfaction. DESIRIAL® PLUS was well tolerated.</p><p><strong>Conclusions: </strong>DESIRIAL® PLUS is an effective and safe treatment option in patients with labia majora hypotrophy or atrophy. This effect goes beyond aesthetic improvement, as treatment was associated with improvement in patients' physical symptoms and sexual function.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"1243-1253"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143541844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unnecessary Antibiotics in Older Female Patients with Recurrent Urinary Tract Infections.","authors":"Elizabeth Critchlow, Alexandra Kuzma, Nathanael Koelper, Surbhi Agrawal, Lauren Dutcher, Lily Arya","doi":"10.1007/s00192-025-06141-x","DOIUrl":"10.1007/s00192-025-06141-x","url":null,"abstract":"<p><strong>Introduction: </strong>Our aim was to describe the rate of unnecessary antibiotic prescriptions across specialties and the frequency of clinical scenarios in which the unnecessary antibiotics were prescribed in older female patients with recurrent urinary tract infections (UTI).</p><p><strong>Methods: </strong>This was a retrospective cohort study of female patients 65 or older with a clinical diagnosis of recurrent UTI. An unnecessary antibiotic was defined as an antibiotic prescribed (i) for asymptomatic bacteriuria (positive culture in the absence of UTI-specific symptoms), (ii) in the absence of UTI-specific symptoms, or (iii) in the presence of documented negative urine culture or negative pyuria. Data on clinical scenarios during episodes when an unnecessary antibiotic was prescribed (such as symptom documentation, urine testing) were extracted and described.</p><p><strong>Results: </strong>The overall rate of unnecessary antibiotics across 454 episodes of antibiotic prescriptions in 175 older female patients with recurrent UTI was 41% and did not significantly differ between specialties (primary care 45%, urogynecology 41%, obstetrics-gynecology 29%, urology 28%, urgent care 27%, p = 0.06). The commonest clinical scenario during which an unnecessary antibiotic was prescribed was absence of documented UTI-specific symptoms (60%) followed by asymptomatic bacteriuria (46%). Other clinical scenarios associated with unnecessary antibiotics included antibiotics prescribed with documented negative pyuria (32%) or negative urine culture (18%). In 11% of episodes, antibiotics were prescribed without any documented UTI-specific symptom and without any testing.</p><p><strong>Conclusion: </strong>Inadequate symptom documentation and inappropriate urine testing contribute to a high rate of unnecessary antibiotic prescribing in older female patients with recurrent UTI. Clinical decision support tools that address these gaps could promote antibiotic stewardship.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"1319-1326"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143983657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to: Robot‑Assisted Laparoscopic Sacrohysteropexy with Autologous Fascia Lata.","authors":"David Hennes, Victoria Buckley, Anna Rosamilia","doi":"10.1007/s00192-025-06188-w","DOIUrl":"10.1007/s00192-025-06188-w","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"1339"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144266151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond the Visible: The Relationship Between Social Appearance Anxiety, Hopelessness, and Depression in Women with Urinary Incontinence.","authors":"Serap Canlı, Yeşim Çetinkaya Şen, İlknur Münevver Gönenç, Ayfer Tezel","doi":"10.1007/s00192-025-06050-z","DOIUrl":"10.1007/s00192-025-06050-z","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to examine the relationship between the severity of urinary incontinence and levels of social appearance anxiety, hopelessness, and depression in women.</p><p><strong>Methods: </strong>A total of 393 women participated in this descriptive and correlational study. Data were collected using the Introductory Information Form, Incontinence Severity Index (ISI), Social Appearance Anxiety Scale (SAAS), Beck Hopelessness Scale (BHS), and Beck Depression Inventory (BDI).</p><p><strong>Results: </strong>Of the participants, 46.3% reported moderate social appearance anxiety, while 25.2% had severe depression. The mean BHS score was 8.80 ± 5.63. No significant correlation was found between the severity of incontinence and social appearance anxiety (p > 0.05). A strong positive correlation was observed between the BDI and BHS scores (p < 0.001). A one-unit increase in age was associated with a 0.172 (B) increase in incontinence severity, and a one-unit increase in BDI score was linked to a 0.137 (B) increase in incontinence severity.</p><p><strong>Conclusions: </strong>The results suggest that increasing age is associated with greater severity of urinary incontinence. Higher incontinence severity is also correlated with higher levels of hopelessness and depression. The psychological impact of urinary incontinence on women's mental health should be addressed, and referrals to psychiatric care should be considered when necessary for a comprehensive treatment approach.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"1197-1206"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice Toward Pelvic Floor Dysfunction Among Postpartum and Postmenopausal Women: A Cross-sectional Study.","authors":"Jing Lin, Bin Yu, Yong He, Ni Tang, Qianying He","doi":"10.1007/s00192-025-06043-y","DOIUrl":"10.1007/s00192-025-06043-y","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This research sought to explore the knowledge, attitude, and practice (KAP) toward pelvic floor dysfunction (PFD) among postpartum and postmenopausal women.</p><p><strong>Methods: </strong>This cross-sectional study was performed among postpartum and postmenopausal women between May and August 2023. Demographic data, along with KAP scores, were collected using a self-designed questionnaire-based approach.</p><p><strong>Results: </strong>Six hundred seventy-seven valid questionnaires were collected and analyzed, with 206 (30.43%) participants aged under 30 years old. The mean scores of knowledge, attitude, and practice dimension were 7.1 ± 2.42 (range 0-9), 33.42 ± 4.75 (range 8-40), and 24.69 ± 6.68 (range 7-35). Proactive practice was independently associated with knowledge scores (OR 1.150, 95%CI 1.059-1.249, P = 0.001), attitude scores (OR 1.125, 95%CI 1.081-1.171, P < 0.001), age 30 years or older (OR 2.326, 95%CI 1.555-3.481, P < 0.001), and being in a postpartum state (OR 0.542, 95%CI 0.325-0.903, P = 0.019). The structured equation model revealed that knowledge exerted a strong positive direct effect on attitude (β = 0.634, P < 0.001), attitude had a significant direct effect on practice (β = 0.681, P < 0.001), and knowledge also markedly influenced practice (β = 0.907, P < 0.001).</p><p><strong>Conclusion: </strong>Postpartum and postmenopausal women demonstrated adequate knowledge, positive attitudes, and proactive practices regarding PFD. It emphasizes the significance of tailored education, a holistic approach, and behavioral interventions to improve clinical practice in pelvic floor health.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"1207-1215"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Urinary, Vaginal, and Perineal Microbiome: Commonalities and Differences.","authors":"Anisa Nasse, Melline Fontes Noronha, Linda Brubaker, Alan J Wolfe","doi":"10.1007/s00192-025-06144-8","DOIUrl":"10.1007/s00192-025-06144-8","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The relationship of adjacent pelvic microbiomes in women has not been well characterized. This study aimed to compare the microbiomes of catheterized urine, vagina, and perineum from well-characterized women undergoing urogynecologic surgery.</p><p><strong>Methods: </strong>Clinical data was extracted from the electronic medical record. Participants contributed three samples (catheterized urine, vaginal swab, perineal swab) that were subjected to DNA sequencing following amplification of hyper-variable region 4 (V4) of the bacterial 16S rRNA gene. The sequences were processed, annotated, and decontaminated. Only participants with sequence-positive samples from all three samples were included in the analytic cohort. Alpha (within-sample) and beta (between-sample) diversity indices were computed, and the microbiome compositions within each participant and across all participants were compared.</p><p><strong>Results: </strong>The mean age of the 104 participants was 60.5 years old (range 35-89) with a mean BMI of 28.2 kg/m²; most (89%) were White. Lactobacillus was the most common genus detected, with a mean relative abundance of 64.8% in the bladder, 67.4% in the vagina, and 42.6% in the perineum. Across these niches, alpha diversity differed significantly, whereas beta diversity was similar. Within an individual, the three microbiomes were very similar to each other, with the bladder and vagina considerably more similar to each other than to the perineum. Taxonomic diversity tended to increase with age and was highest in overweight participants.</p><p><strong>Conclusion: </strong>The microbiomes of the bladder, vagina, and perineum of women are very similar to each other.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"1173-1186"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143979067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Outcomes Following Vaginal versus Laparoscopic Uterosacral Ligament Suspension.","authors":"Sarah Sears, Megan Abrams, Kasey Palm, Susan Wherley, Robert Pollard, Jeffrey Mangel, David Sheyn","doi":"10.1007/s00192-025-06132-y","DOIUrl":"10.1007/s00192-025-06132-y","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Long-term outcomes following vaginal (V-USLS) versus laparoscopic (L-USLS) uterosacral ligament suspension have not been reported in the literature. Our objective was to compare long-term outcomes following V-USLS versus L-USLS following hysterectomy.</p><p><strong>Methods: </strong>This was an ambispective cohort study at a single academic institution comparing patients who underwent a V-USLS following a vaginal hysterectomy or L-USLS following a laparoscopic hysterectomy from 2013 to 2018. The primary outcome was composite prolapse recurrence rate, combining subjective prolapse symptoms and objective failure, including prolapse beyond the hymen on pelvic organ prolapse quantification exam or retreatment. A power calculation determined 68 patients in each group would be required to detect a difference of 15% in recurrence rates. Statistical analysis was performed using Student' t-test, Wilcoxon rank sum test, chi-square test, or Fishers exact test, and multivariable logistic regression where appropriate.</p><p><strong>Results: </strong>Thirty-six patients in each group presented for a study visit. Preoperative POP-Q measurements were similar between groups. Surgical complication rates were low and similar between groups. Mean follow-up time was 6.8 years, similar between groups. V-USLS had higher rates of recurrent prolapse beyond the hymen on POP-Q (33.2% vs 11.1%, p = 0.016), retreatment (25.0% vs 2.8%, p = 0.006), and composite failure (47.2% vs 22.2%, p = 0.019). Subjective prolapse symptoms were similar between groups. V-USLS was associated with a higher risk of prolapse recurrence (aOR 1.73 (95%CI 1.13-5.78). Anterior prolapse (Aa) was associated with higher recurrence risk, with aOR 2.04 (95%CI 1.15-3.62) per every 1 cm, up to 3 cm beyond the hymen.</p><p><strong>Conclusions: </strong>On the basis of these results, L-USLS appears to have a decreased association with recurrence compared to V-USLS. Conclusions are limited by a small sample size.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":"1293-1299"},"PeriodicalIF":1.8,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}