Lin Zhang, Nian Cai, Li Mo, Xiaofang Tian, Hongcen Liu, Bohai Yu
{"title":"Global Prevalence of Overactive Bladder: A Systematic Review and Meta-analysis.","authors":"Lin Zhang, Nian Cai, Li Mo, Xiaofang Tian, Hongcen Liu, Bohai Yu","doi":"10.1007/s00192-024-06029-2","DOIUrl":"https://doi.org/10.1007/s00192-024-06029-2","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This study aims to systematically estimate the global prevalence of overactive bladder (OAB), identify demographic and regional factors contributing to prevalence variations, and assess trends in prevalence over the past two decades.</p><p><strong>Methods: </strong>This cross-sectional study was conducted according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guideline. From inception to April 2024, computerized searches for OAB prevalence-related literature were conducted on PubMed, Embase, Web of Science, and Cochrane. Studies of OAB prevalence in the general population were included. Two independent researchers conducted the screening, data extraction, and quality assessment of the included studies.</p><p><strong>Results: </strong>A total of 53 studies, encompassing 610,438 participants, were ultimately included in the analysis. The meta-analysis determined the global prevalence of OAB to be 20% (95% CI 0.18-0.21). Over the past 20 years, there has been an increase in OAB prevalence, rising from 18.1% (95% CI 0.13-0.23) to 23.9% (95% CI 0.19-0.29). Among women, the prevalence of OAB was 21.9% (95% CI 0.20-0.24), indicating higher rates compared to men (OR = 16.1, 95% CI 0.15-0.18). The study also found higher prevalence rates among overweight and obese individuals (OR = 18.6, 95% CI 0.13-0.24) and those aged 60 years and above (OR = 28.3, 95% CI 0.24-0.33). Middle-income countries exhibited higher prevalence rates compared to high-income countries.</p><p><strong>Conclusions: </strong>The study highlights higher risks of OAB among obese individuals, women, and the elderly. OAB prevalence has shown an increasing trend over the past 20 years.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143414074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Haipeng Ren, XuPeng Wu, Jian Wang, Yaqun Zhang, Xu Wang
{"title":"A2A Adenosine Receptor as a Potential Therapeutic Target in Cystitis-Induced Bladder Pain: Insights from a Transgenic Autoimmune Cystitis Murine Model.","authors":"Haipeng Ren, XuPeng Wu, Jian Wang, Yaqun Zhang, Xu Wang","doi":"10.1007/s00192-025-06078-1","DOIUrl":"https://doi.org/10.1007/s00192-025-06078-1","url":null,"abstract":"<p><strong>Purpose: </strong>Bladder pain syndrome (BPS) is associated with heightened inflammatory responses. We hypothesize that reduced A2A adenosine receptor (A2AR) expression exacerbates inflammation and pain, while A2AR activation mitigates these effects. In this study, we aimed to investigate the therapeutic potential of A2AR modulation in an autoimmune cystitis model.</p><p><strong>Methods: </strong>URO-OVA mice, a transgenic model that expresses ovalbumin (OVA) in the bladder urothelium leading to autoimmune-driven cystitis, were randomly divided into four groups (n = 6 per group): (1) control, (2) inflammation-induced (cystitis), (3) inflammation-induced treated with the A2AR agonist regadenoson (a selective A2AR agonist commonly used in cardiac stress tests), and (4) inflammation-induced treated with the A2AR antagonist ZM241385. Bladder inflammation was assessed via histological analysis, western blot, and RT-PCR of inflammatory markers (IL-6, TNF-α, CD11b, GFAP, HMGB1). Bladder pain was measured using bladder distention-evoked visceromotor responses (VMR) and von Frey filament-based pelvic nociception tests.</p><p><strong>Results: </strong>Inflammation-induced mice showed significantly reduced A2AR expression (~50% lower vs. controls, p < 0.001), while other inhibitory factors (e.g., IL-10R, TGF-βR, PD-1) remained largely unchanged. Regadenoson treatment reduced IL-6 and TNF-α expression by ~60% compared to cystitis-induced mice and alleviated pain, whereas ZM241385 worsened inflammation and increased pain responses.</p><p><strong>Conclusion: </strong>A2AR downregulation correlates with increased inflammation in the URO-OVA model of BPS. Activation of A2AR via regadenoson significantly suppresses inflammatory responses and bladder pain, suggesting A2AR is a promising therapeutic target for BPS.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ana Silvia Seki, Ana Maria Homem de Mello Bianchi-Ferraro, Tatiana Carvalho Sousa Bonetti, Eliana Suelotto Machado Fonseca, Marair Gracio Ferreira Sartori, Zsuzsanna Ilona Katalin de Jarmy-Di Bella
{"title":"How Long Does Urinary Continence Last After Treatment with Intravaginal CO<sub>2</sub> Laser and Microablative Radiofrequency? A Four-Year Follow-up of a Multi-arm Randomized Clinical Trial (LARF-arm3).","authors":"Ana Silvia Seki, Ana Maria Homem de Mello Bianchi-Ferraro, Tatiana Carvalho Sousa Bonetti, Eliana Suelotto Machado Fonseca, Marair Gracio Ferreira Sartori, Zsuzsanna Ilona Katalin de Jarmy-Di Bella","doi":"10.1007/s00192-025-06076-3","DOIUrl":"https://doi.org/10.1007/s00192-025-06076-3","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>CO<sub>2</sub> laser (LS) and microablative radiofrequency (RF) are outpatient options for stress urinary incontinence (SUI) treatment. The aim of this study was to evaluate the lasting effects of SUI treatment using intravaginal CO<sub>2</sub> LS and microablative RF.</p><p><strong>Methods: </strong>This is a long-term follow-up of a prospective double-blind multi-arm randomized controlled trial, involving women with pure or predominant SUI. Participants received three monthly sessions of LS, RF, or were part of a sham control group (SCT) and were followed up, every 6 months, for 48 months to assess continence rates, defined by the composed outcome: no symptoms, negative stress test, and negative 7-day voiding diary.</p><p><strong>Results: </strong>One hundred and thirty-nine women were eligible and randomized into the three groups. One hundred and fourteen participants concluded the treatment protocol. The women's mean age was 50.4 (± 9.5) years. The results showed that both LS and RF treatments led to a mean duration of urinary continence of 26.7 months and 24.58 months respectively, compared with 8.21 months in the SCT group. No major complications were observed.</p><p><strong>Conclusion: </strong>Although the continence rates declined over the time, more than 50% of women in perimenopause, with mild to moderate SUI, pure or predominant SUI, remained without complaints of SUI for at least 24 months after LS or RF application sessions, with no major complications reported.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Efficacy of Two Modes of Transvaginal Temperature-Controlled Radiofrequency for Female Stress Urinary Incontinence.","authors":"Xiao-Xiao Wang, Ying Xu, Yan-Feng Song, Xiao-Hua Zheng, Xiao-Xiang Jiang, Chao-Qin Lin","doi":"10.1007/s00192-025-06065-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06065-6","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>This study was aimed at comparing the efficacy of different modes of transvaginal temperature-controlled radiofrequency (TTCRF) in improving female stress urinary incontinence (SUI).</p><p><strong>Methods: </strong>A randomized trial with a nested prospective cohort included 89 women with SUI, who were randomized into a unipolar group (n = 35) and a comprehensive group (n = 54). The comprehensive mode group was treated with unipolar and bipolar combination therapy. The 1-h pad test (1-h PWT) was used as the primary metric by which to gauge improvement of SUI. The effective rate was defined as (cure + improvement cases/total cases) × 100%. Daily leakage episodes and urinary incontinence questionnaires were also documented to compliment this metric in assessing treatment efficacy. Patient satisfaction was assessed and adverse reactions were monitored.</p><p><strong>Results: </strong>No significant difference in the effective rate between the unipolar and comprehensive groups was observed at 1, 3, 6, and 12 months after the end of treatment (62.9% vs 66.7%, 68.6% vs 68.5%, 80.0% vs 71.7%, 74.3% vs 62.5% respectively). Objective improvement of SUI symptoms and subjective satisfaction for all SUI patients were achieved after TTCRF treatment. Ten-course treatment of TTCRF achieved significantly greater treatment effects than five-course treatment as measured by 1-h PWT, daily leakage episodes, International Consultation on Incontinent Questionnaire-Short Form, and Pelvic Organ Prolapsed-Urinary Incontinence Sexual Questionnaire-12. No significant side effects occurred in any patients during treatment.</p><p><strong>Conclusions: </strong>We consider TTCRF treatment to be a viable outpatient option for SUI, with unipolar and comprehensive modes both showing similar efficacy for SUI.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Nienke J E Osse, Marian K Engberts, Hugo W F van Eijndhoven, Paul L P Brand, Marco H Blanker
{"title":"Patients' Perceptions of Stress Urinary Incontinence Treatment: A Scoping Review of Qualitative Studies.","authors":"Nienke J E Osse, Marian K Engberts, Hugo W F van Eijndhoven, Paul L P Brand, Marco H Blanker","doi":"10.1007/s00192-025-06061-w","DOIUrl":"https://doi.org/10.1007/s00192-025-06061-w","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Treatment options for female stress urinary incontinence (SUI) are often offered in a stepped-care approach. However, the shift towards patient-centred care and shared decision making (SDM) has prompted an increased interest in patients' perceptions of treatment decision making. This scoping review maps the available qualitative research on women's perceptions of the treatment decision-making process for SUI and identifies knowledge gaps.</p><p><strong>Methods: </strong>This scoping review was performed according to the Preferred Reporting Items for Systematic review and Meta-Analysis guidelines. Three databases were searched using a systematic search strategy, without restriction in publication date or language. After thorough screening, 19 of the initial 3,473 publications were included.</p><p><strong>Results: </strong>Four themes were identified; pre-existing experiences and notions that women bring to the consultations (things women consider before their consultation); treatment and patient characteristics (treatment aspects and personal values patients deem important); aspects of the consulting health care professional and facilities (availability of treatment options and counselling styles of physicians); ways of reaching a decision (three different ways that women used to make their decision. There were gaps in the literature on aspects affecting women's treatment preferences, their preferred decision-making style and how they want to be involved in this decision-making process.</p><p><strong>Conclusions: </strong>This scoping review provides a global overview of women's perceptions on and preferences for treatment for SUI, and highlights a lack of knowledge on women's ideas of the treatment decision process. To provide clinicians with better guidance for their counselling and decision-making approaches, studies on women's perceptions of the decision-making process and the different decision-making styles are needed.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Francis G Muriithi, Corlia Brandt, Dakalo Muavha, Onesmus Byamukama, John Paul Bagala, Monika Vij
{"title":"Workload, Availability of Diagnostic Tools, and Treatment Options for Urinary Incontinence and Other Pelvic Floor Disorders in Women: An Online Survey on Practice and Challenges Faced by Providers of Urogynaecological Healthcare in Ten African Countries.","authors":"Francis G Muriithi, Corlia Brandt, Dakalo Muavha, Onesmus Byamukama, John Paul Bagala, Monika Vij","doi":"10.1007/s00192-025-06072-7","DOIUrl":"https://doi.org/10.1007/s00192-025-06072-7","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Pelvic dysfunction, including urinary incontinence, significantly impacts the quality of life of affected women, diminishing their freedom and dignity. In many African countries, challenges such as limited funding, competing health priorities and cultural stigma on pelvic health further restrict access to care. This information gap may hinder the effective design and implementation of interventions aimed at improving urogynaecological healthcare delivery. The objective of this study was to estimate the urogynaecological workload, the availability of tools to investigate and treat urinary incontinence in women, and to understand the challenges faced by providers of urogynaecological healthcare in 10 African countries.</p><p><strong>Methods: </strong>A cross-sectional online survey of urogynaecological service providers.</p><p><strong>Results: </strong>Forty-seven responses were analysed, revealing that 40% of gynaecological consultations addressed urogynaecological concerns, with 60% related to prolapse, 40% to bladder issues, 7.5% to bowel problems and 5% to sexual dysfunction. Among bladder issues, 35% involved obstetric fistulas, 22.5% stress urinary incontinence, 12.5% mixed urinary incontinence and 10% overactive bladder. Identified resource gaps included insufficient numbers and training of providers, limited access to diagnostic tools such as urodynamics equipment, and inadequate availability of neuromodulation and advanced surgical options. Key challenges in healthcare delivery were lack of patient awareness and inadequate funding, especially in public-sector facilities.</p><p><strong>Conclusion: </strong>Gaps exist in the access and delivery of urogynaecological healthcare to patients with pelvic floor dysfunction in sub-Saharan Africa. Specific areas of focus should include patient education and capacity building, including human resources, access to affordable screening and diagnostic tools and technologies, and investment in affordable management options.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor: The Association Between Depression and Overactive Bladder: A Cross-Sectional Study of NHANES 2011-2018.","authors":"Yunyun Pan","doi":"10.1007/s00192-025-06075-4","DOIUrl":"10.1007/s00192-025-06075-4","url":null,"abstract":"","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143373592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qing Feng, Kun Wang, Wan T Xu, Jian M Huang, Hui H Yang, Yu He
{"title":"The Use of Transperineal Ultrasonography to Compare Relevant Factors for Postpartum Urinary Incontinence Related to Different Modes of Delivery.","authors":"Qing Feng, Kun Wang, Wan T Xu, Jian M Huang, Hui H Yang, Yu He","doi":"10.1007/s00192-025-06073-6","DOIUrl":"https://doi.org/10.1007/s00192-025-06073-6","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>Studies concerning the similarities and differences in relevant factors for PPUI in puerpera with delivery modes are scarce. This study aimed to investigate relevant factors for PPUI among primiparas grouped by different delivery modes using transperineal ultrasonography.</p><p><strong>Methods: </strong>This is a retrospective cohort study. Seven hundred thirty-eight primiparas were included and their clinical and ultrasonographic data were collected. First, they were divided into the UI group (n = 233) and non-UI group (n = 505). Then all participants were redivided into the vaginal delivery without episiotomy group (n = 271), the vaginal delivery with episiotomy group (n = 158), and the cesarean section group (n = 309). Independent relevant factors of PPUI were analyzed with the delivery mode as one of the variables and as a grouping factor, respectively.</p><p><strong>Results: </strong>BMI, delivery modes, vertical distances between the location of bladder neck and the reference line of the inferior symphyseal margin at rest (BSDr), and [bladder neck descent (BND)]/BSDr were independently associated with PPUI in the overall study population. Among the participants grouped by delivery modes, the maternal BMI, BSDr, and retrovesical angle during Valsalva maneuver (RVAv) were independently associated with PPUI in the vaginal delivery without episiotomy group. BND/BSDr was the independent relevant factor of PPUI in the cesarean section group. In the vaginal delivery with episiotomy group, no factors were independently associated with PPUI.</p><p><strong>Conclusions: </strong>The independent relevant factors for PPUI in primiparas varied with delivery modes. Sonographic measurements were independently associated with PPUI related to different delivery modes, acting as differential markers to identify PPUI.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364875","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sascha Vereeck, James Alexander, Michael Carey, Anna Rosamilia
{"title":"Outcome of Laparoscopic Versus Vaginal High Uterosacral Ligament Vault Suspension at the Time of Hysterectomy.","authors":"Sascha Vereeck, James Alexander, Michael Carey, Anna Rosamilia","doi":"10.1007/s00192-024-06033-6","DOIUrl":"https://doi.org/10.1007/s00192-024-06033-6","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>High uterosacral ligament suspension (HUSLS) can be used to treat apical pelvic organ prolapse (POP). This can be performed both vaginally and laparoscopically. Data comparing the two suspension procedures remain limited. The aim of this study is to compare the effectiveness and safety of vaginal HUSLS and laparoscopic HUSLS at the time of hysterectomy.</p><p><strong>Methods: </strong>This is a retrospective cohort study of women who underwent hysterectomy between 2019 and 2021 at a tertiary urogynaecology unit. Either vaginal or laparoscopic hysterectomy was performed, followed by vaginal or laparoscopic HUSLS respectively. Women were followed up at 6 weeks, and at 6 and 12 months postoperatively. The primary outcome was symptomatic recurrence of vaginal bulge symptoms. Secondary outcomes were anatomical recurrence, re-treatment and safety.</p><p><strong>Results: </strong>A total of 111 women met the inclusion criteria. Twelve were excluded, leaving 99 for analysis. HUSLS was performed vaginally in 47 and laparoscopically in 52 women. There was no significant difference in demographics between the groups. At 12 months, 92% in the vaginal group and 48% of the laparoscopic group reported no symptoms of prolapse, 67% vs 36% had no anatomical recurrence and 0% vs 34% had re-treatment respectively. Logistic regression (adjusting for age, BMI, menopausal status, preoperative stage apical prolapse, procedure type) demonstrated that the laparoscopic route was the only variable associated with recurrent prolapse at or beyond the hymen and symptomatic prolapse at 12 months.</p><p><strong>Conclusions: </strong>Symptomatic and anatomical recurrent POP was associated with this technique of laparoscopic HUSLS. Further research should consider prospective evaluation of these or modified techniques.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andressa Soares Castro Alves, Maita Poli de Araújo, Gláucia Miranda Varella Pereira, Luiz Gustavo Oliveira Brito, Cássia Raquel Teatin Juliato
{"title":"Influence of Powerlifting and Weightlifting on Female Pelvic Floor Dysfunction: Systematic Literature Review.","authors":"Andressa Soares Castro Alves, Maita Poli de Araújo, Gláucia Miranda Varella Pereira, Luiz Gustavo Oliveira Brito, Cássia Raquel Teatin Juliato","doi":"10.1007/s00192-025-06059-4","DOIUrl":"https://doi.org/10.1007/s00192-025-06059-4","url":null,"abstract":"<p><strong>Introduction and hypothesis: </strong>The participation of women in sports such as powerlifting and weightlifting has grown over the years, and there is no consensus on the role of exercises in pelvic floor disorders (PFDs). We aimed to identify and summarize the current evidence on the impact of powerlifting and weightlifting on PFDs.</p><p><strong>Methods: </strong>A systematic literature search was conducted on databases with no language restriction, from inception to 20 January 2024. We included observational studies or randomized controlled trials investigating female athletes in powerlifting or weightlifting providing information regarding the impact of these sports on pelvic floor structures. Studies on CrossFit trainers, nonfemale athletes, age <18, and congress abstracts were excluded. Two researchers independently performed the data extraction and quality assessment. The risk of bias was assessed using the Risk Of Bias In Non-randomized Studies-of Interventions. The main outcomes were the prevalence of PFDs in women practicing powerlifting or weightlifting, the factors associated with PFDs, and exercise related to urinary loss.</p><p><strong>Results: </strong>Of the 221 articles found, 5 studies with 1,809 participants were included in the qualitative synthesis. The prevalence of urinary incontinence (UI) in powerlifters ranged from 41.0% to 48.8% and in weightlifters from 36.6% to 54.1%. The main associated factors were age, parity, and body mass index. Deadlift was the exercise most commonly associated with UI (42.5%), followed by squats (36.3%). High loads and repetitions, along with competitions, were associated with UI.</p><p><strong>Conclusion: </strong>This systematic review reveals a clear connection between PFD, particularly UI, and the engagement of women in powerlifting and weightlifting.</p>","PeriodicalId":14355,"journal":{"name":"International Urogynecology Journal","volume":" ","pages":""},"PeriodicalIF":1.8,"publicationDate":"2025-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364870","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}