International Journal of ChemTech Research最新文献

{"title":"Comparison of Hand Grip Strength in patients with Distal\u0000Radius Fracture that are treated by Closed Reduction with\u0000Cast versus Open Reduction and Internal Fixation in Haji\u0000Adam Malik Hospital Medan","authors":"Adri Yandra Hidayat, Nino Nasution, I. D. Winanto","doi":"10.20902/ijctr.2019.130110","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130110","url":null,"abstract":"BackgroundDistal radius fracture is quite often found in emergency settings. There are many options to assess the outcome of treatment in distal radius fracture cases. One option that can be done is to measure the strength of the injured handgrip. Patient often complained about the decrease in ability to grasp and rotate and bear the burden after distal radius fracture. Objective-To find out the comparison of the hand grip strength in patients with distal radius fractures that are treated by closed reduction and casting to open reduction and internal fixation. Material and Methods-The study was conducted in a retrospective, observational analytic study with a cross sectional approach, which aimed to analyze the comparison of hand grip strength in patients with distal radius fractures that are treated by closed reduction and casting to open reduction and internal fixation12 months after treatment. Target population was all patients with distal radius fracture who underwent closed reduction and casting and open reduction and internal fixation in all inpatient at Adam Malik Hospital, Medan. ResultsIn this study the distribution of the number of samples was as many as 57 subjects with 17 are women (29.8%) and 40 are men (70.2%). 18 years old is the youngest age of the samples and the oldest is 76 years old with a mean of 32.77 ± 14.03 years. Based on the mechanism of injury : motor vehicle accidents is the most common mechanism of injury, it accounts 45 people (78.9%). According to time arrivals mostly patient came <24 hours. There are 11 extraarticular fractures ( 19.3%) and 46 intraarticular fractures (80.7%), there were 24 people (42.1%) fracture in the right hand and 33 people (57.9%) in the left hand. Statistical analysis shows that there is no difference in the ratio of hand grip strength with significance value of (p value) 0.881 (> 0.05). ConclusionThere were no significant differences in the clinical outcome of the patient's hand grip strength in patients that are treated with closed reduction and casting to open reduction intenal fixation after 12 months post theraphy.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"20 1","pages":"84-89"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89871136","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Strontium doping on Thermal and\u0000Optical properties of Gel grown Copper cadmium and Cobalt\u0000cadmium oxalate crystals","authors":"P. S. Rohith, N. Jagannatha, Pradeepkumar K.V","doi":"10.20902/ijctr.2019.130304","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130304","url":null,"abstract":"In the present paper, the Sr doped Copper cadmium oxalate (CuCO) and Cobalt cadmium oxalate (CoCO) crystals were grown by the single diffusion method in silica hydrogel at room temperature. Optimum conditions of the as-grown crystals were established by varying different growth parameters. Energy-dispersive X-ray analysis (EDX) confirmed the presence of major elements such as Sr 2+ , Co 2+ , Cu 2+ , Cd 2+ ions in the lattice of the grown crystals. The percentage weight loss, molecular weight and thermal stability of the grown crystals were studied using Thermogravimetric analysis (TGA). The Energy gap, refractive index, reflectance and electrical polarizability of the crystals were calculated by using UVVisible spectroscopy. Direct and Indirect band gaps are calculated using Tauc’s plot.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"16 1","pages":"91-98"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75341805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pharmaceutical Co-crystal : An Emerging Technique to\u0000enhance Physicochemical properties of drugs","authors":"Diksha Patel, P. Puranik","doi":"10.20902/ijctr.2019.130326","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130326","url":null,"abstract":"Major constraints in development of new product are poor aqueous solubility, stability and low oral bioavailability, low permeability. As majority of drugs marketed worldwide are administered by oral route and about 40% -50% of the new molecular entities were never invade into the market because of such biopharmaceutical issues.So issues related to poor physiochemical property of an active pharmaceutical ingredient (API) can be resolved using co‐ crystallization approach.Crystallization emerge as potential technique for enhancement of solubility of poorly aqueous soluble drugs also helps to improve physicochemical with preserving the pharmacological properties of the API . Cocrystals are solids that are crystalline single-phase materials composed of two or more different molecular and/or ionic compounds generally in a stoichiometric ratio which are neither solvates/hydrates nor simple salts. It is multicomponent system in which one component is API and another is called coformer. Coformer selection is the main challenging step during cocrystal synthesis , so various screening methods for the selection of coformers was explained . This article also summarizes differences between cocrystals with salts, solvates and hydrates along with the implications and limitations of cocrystals .It also provides a brief review on different methods of cocrystal formation and characterization techniuqes of cocrystals. Lastly this article highlights 85 synthetic and 14 herbal cocrystals along with its method of preparation and coformers used.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"29 1","pages":"283-290"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75934946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimation and Removal of Hazardous Aromatic Amines by\u0000the Oxidation with NaIO4 Spectrophotometrically : A Review","authors":"Payal Rathi","doi":"10.20902/ijctr.2019.130301","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130301","url":null,"abstract":"Many aromatic amines are the toxic in nature and impact a harmful effect in the body. Conversion of such carcinogenic aromatic amines in to other non carcinogenic compound by the oxidation process through sodium meta periodate is a good attempt in this way. Spectrophotometric method have been used for achieve the optimum condition and the estimation of aromatic amines.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"1 1","pages":"69-72"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81245700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Potential Benefits of Diesel Aloe Vera Emulsified Fuel in A\u0000Non-Road Diesel Engine","authors":"V. Yogesh, A. Vignesh","doi":"10.20902/ijctr.2019.130401","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130401","url":null,"abstract":"In this paper, an experimental attempt has been made to improve the performance and emission of a non-road diesel engine using adiesel aloe vera emulsified fuel (A10). Two fuel samples such as neat diesel (D100) and diesel aloe vera emulsified fuel referred to as A10 (10% aloe vera, 89% diesel, 1% surfactant) was used to conduct the experiments and the obtained results were compared. The experiments were carried out on a single cylinder non-road Genset diesel engine at low load (BMEP 1.54 bar), mid load (BMEP 3.09 bar) and high load(BMEP 4.63 &6.18 bar) conditions.The experimental results show that the dieselaloe vera emulsified fuel resulted in reduced nitric oxide (NO) with increased brake thermal efficiency (BTE). overall, a 19.24% reduction in NO emission and a 9.82% increase in BTE was observed. Also, it was noticed that the A10 prolonged the ignition delay and improved the air-fuel mixing inside the combustion chamber.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"13 1","pages":"333-341"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81963688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of Pure and Hybrid Nanoparticles using Ionic\u0000Liquid as a Capping agent","authors":"N. Santhi, K. Rajathi, S. Sridhar","doi":"10.20902/ijctr.2019.130410","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130410","url":null,"abstract":"Ionic liquids are exceptional chemical compounds that are used in many areas of modern science. Due to their highly adjustable nature and incomparable properties, ionic liquids have become key players in the areas of synthesis, catalysis, extraction, electrochemistry, analysis, biotechnology, etc. In addition to the physical and chemical properties of ionic liquids, their high biological activity has attracted considerable attention from biochemists, ecologists and medical professionals. Due to the properties mentioned above, an imidazolium ionic liquid solvent was used for the synthesis of nanostructure nanoparticles. In the present work, cubic form of pure Fe2O3, spherical nature of pure Ag (0) and hexagonal shaped hybrid AgFe2O3 were successfully synthesized by a simple co-precipitation, reduction and co-precipitation processes. The synthesized nanoparticles were characterized in detail by spectral studies such as IR, XRD, SEM, EDX and TEM analysis. The size and shape of the particles were performed by X-ray Diffraction (XRD), Scanning Electron Microscope (SEM) techniques and Transmission Electron Microscope (TEM) techniques. Quality quantity and purity of the products was checked by Energy Dispersive X-Ray Analysis (EDX).","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"17 1","pages":"413-419"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84229098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"8-Anilino-1-naphthalenesulfonate (ANS) as a probe for\u0000Poly(vinyl alcohol)(PVA) swelling","authors":"J. Shaik, Anitha C. Kumar","doi":"10.20902/ijctr.2019.130207","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130207","url":null,"abstract":"Poly (vinyl alcohol) (PVA) is a hydrophilic polymer developed for biomedical applications. Swelling properties of PVA gels is very important for its drug delivery applications. There are many ways to study the swelling behaviour. Here we are proposing a fluorescent study by using 8-anilino-1-naphthalenesulfonate (ANS) as an extrinsic fluorescent probe. When ANS incorporated PVA films are allowed to swell in water, there is a loss of fluorescence intensity at 453 nm and there is a new peak at 500 nm. Thus, ANS is proposed as a fluorescent probe for the sensing of hydration of PVA.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"26 1","pages":"54-60"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86117334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current Drug Repurposing Strategies in Treatment of\u0000COVID-19","authors":"Kapish Kapoor, Abbas Sanawedwala, Deeksha Rajput, Shreya Bhardwaj, Kriti Shrivastav, N. Dhingra","doi":"10.20902/ijctr.2019.130309","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130309","url":null,"abstract":"Drug repurposing is the process of finding the new uses of existing drugs. It is one of the emerging methods involved in selecting a molecule for diseases which are communicable and can spread in the general population at a faster pace. The method is selected over conventional drug discovery methods because it is a faster way to bring an existing molecule for a different disease. Ever since COVID-19 pandemic has emerged worldwide use of repurposed drugs has become an important toll to tackle this viral disease. This review is a study of the varous stargegies of drug reprposing for the treatment of COVID19.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"21 1","pages":"125-131"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85296960","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synthesis and SAR Evaluation of Mercaptotriazolo\u0000derivatives as anti-inflammatory agents.","authors":"S. Mamatha, S. L. Belagali, M. Bhat","doi":"10.20902/ijctr.2019.130123","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130123","url":null,"abstract":"A new series of benzothiazole appended triazole derivatives were synthesized. Characterization is done by FT-IR, Mass, 1 H and 13 C NMR spectroscopic techniques. The newly synthesized compounds were screened for antioxidant and anti inflammatory activities. Experimental data hypothesized compound 7b as highly potent cytotoxicant with lengthened activity. Structure–activity relation interrelates the biological activity and chemical moiety of the molecule. Structurally, 7b is a benzothiazolyltriazole having a pyrrolidine group (five membered ring) attached to two CH2 groups and methyl substituent at 7 th position of the benzothiazole ring.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"295 ","pages":"187-198"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91454234","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Seed Extract of Dypsis lutescens as Ecofriendly Corrosion\u0000Inhibitor for Mild Steel in Hydrochloric Acid Medium","authors":"G. R. Thusnavis, T. Archana, K. P. V. Kumar, M. Pillai","doi":"10.20902/ijctr.2019.130118","DOIUrl":"https://doi.org/10.20902/ijctr.2019.130118","url":null,"abstract":"The seed extract of Dypsis lutescens, had been analyzed for mild steel corrosion inhibition in acid medium with weight loss, thermodynamic, adsorption and electrochemical parameters. The results reflected that the extract is a potential corrosion inhibitor. IR spectra and SEM photographs recorded for functional group and surface modification analysis of mild steel, were agreeing with other parameters. Entire study revealed that the inhibitor works through adsorption of its molecules over the mild steel. From this study it is inferred that the seed extract of D. lutescens is an efficient, eco-friendly and alternate corrosion inhibitor for mild steel in acid medium.","PeriodicalId":13853,"journal":{"name":"International Journal of ChemTech Research","volume":"23 1","pages":"149-158"},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83332061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}