International Journal of Clinical Practice最新文献

{"title":"Lymphocyte-to-Monocyte Ratio as a Prognostic Biomarker for Acute Myocardial Infarction: A Systematic Review and Meta-Analysis","authors":"Hanshuo Gu,&nbsp;Yian Lu,&nbsp;Jiaxin Luo,&nbsp;Zhaoshun Yuan","doi":"10.1155/ijcp/5560827","DOIUrl":"https://doi.org/10.1155/ijcp/5560827","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> The prognostic value of lymphocyte-to-monocyte ratio (LMR) for acute myocardial infarction (AMI) has been underscored by multiple studies. Therefore, we initiated this meta-analysis to examine the correlation between LMR and prognostic outcomes in patients with AMI.</p>\u0000 <p><b>Methods:</b> A comprehensive literature search was conducted across multiple databases, including Embase, PubMed, Web of Science, and the Cochrane Library, covering the period from the inception of the databases to October 24, 2024, focusing on studies comparing mortality and/or incidence of major adverse cardiovascular events (MACEs) by the pooled odds ratios (ORs) and respective 95% confidence intervals (CIs) between different LMR levels in AMI patients.</p>\u0000 <p><b>Results:</b> Our meta-analysis encompasses 11 studies and involves a total of 7719 patients. The results indicate that individuals in the lower LMR group exhibit notably elevated mortality rates (OR = 2.43, 95% CI: 1.46–4.04, and <i>p</i> = 0.0006) and increased incidence of MACE (OR = 1.57, 95% CI: 1.27–1.95, and <i>p</i> = 0.0001) compared with those with high LMR. Subgroup analysis further reveals that lower LMR correlated with higher mortality and MACE in the context of confounding factors such as the sample size and cutoff value.</p>\u0000 <p><b>Conclusion:</b> Our meta-analysis confirms the prognostic value of LMR in AMI patients. Lower LMR levels correlate with elevated mortality and increased incidence of MACE. This implies the clinical potential of LMR as an effective prognostic biomarker aiding in better risk assessment, personalized treatment strategies, and improved clinical outcomes.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5560827","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Health Knowledge of Undergraduate College Students During the COVID-19 Global Pandemic","authors":"Janie R. Robinson,&nbsp;Glenda Daniels,&nbsp;Jacquelyn S. Pennings,&nbsp;Jermaine Rucker","doi":"10.1155/ijcp/5545760","DOIUrl":"https://doi.org/10.1155/ijcp/5545760","url":null,"abstract":"<div>\u0000 <p>Health knowledge and health literacy are key factors that influence health promotion and disease prevention. During the COVID-19 pandemic, undergraduate college students were faced with multiple stressors that influenced their health. Health knowledge and health literacy could have improved their overall health outcomes. The purpose of this study was to explore health perceptions, health behaviors, the impact of the COVID-19 pandemic, general health knowledge, and understanding of health disparities in undergraduate college students. Students were recruited through the university’s email. An online Qualtrics survey was distributed through the email system to a stratified random sample. Two-hundred eleven students participated in the study. The majority of respondents were female (71.5%) and Caucasian (61.1%) and reported excellent or good physical health (80.6%). However, over 40% reported only fair/poor mental health (44.3%). Nonwhite students had 2.2 times higher odds of not having had a well-visit within the past 2 years. Students with lower parental income had higher odds of reporting a negative financial impact of the COVID-19 pandemic. Increased stress, mental health issues, social isolation, and financial issues were the most reported effects of the COVID-19 pandemic. Students expressed that discussing mental health was uncomfortable, and there is a stigma associated with mental illness. Students who were older than 21 years of age displayed a higher health knowledge than younger students. Almost half of the students demonstrated a basic knowledge of the definition of health disparities. While a majority of the students in this study engaged in healthy behaviors, the findings revealed that there was a reluctance to express feelings of mental health. This reluctance could lead to mental distress. Therefore, university programs are needed to assist students with discussing mental health and identifying appropriate resources. Understanding health can decrease stressors related to illness and can improve mental and physical health in the long term.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5545760","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143595294","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"In the Third Year of the COVID-19 Pandemic, the Worry of Applying to the Prosthodontics Clinic or Transmitting COVID-19 to Relatives Can Cause Anxiety/Depression and Not Being Able to Wear a Mask During Treatment Can Also Cause Anxiety","authors":"Hatice Lamia Elif Sagesen,&nbsp;Sezgi Cinel Sahin,&nbsp;Cagri Koyal","doi":"10.1155/ijcp/8888157","DOIUrl":"https://doi.org/10.1155/ijcp/8888157","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To evaluate the anxiety and depression levels and the factors affecting them in the patients who applied to the Prosthodontics Clinic during the end of the pandemic process with the ‘Hospital Anxiety and Depression Scale (HADS)’.</p>\u0000 <p><b>Methods:</b> To determine the symptoms of anxiety and depression, probable cause questions and the “Turkish version of the HADS” were applied to the volunteers who applied to the Prosthodontics Clinic. In the study, independent groups t- and one-way ANOVA tests were used to compare the data according to the groups, the Chi-square test was used for the relationships between group variables, and logistic regression analysis was used to determine the factors affecting anxiety and depression.</p>\u0000 <p><b>Results:</b> A total of 194 volunteers (96 male, 98 female) were included in the study. Of the participants, anxiety was detected in 42.3%, depression was detected in 58.8%, and the HADS average was measured as 15.97 ± 7.66. In the depression score classification, the difference between the depression scores of nonsmoking participants (7.8 ± 4.03) and smokers (9.07 ± 3.36) was found to be statistically significant (<i>p</i> = 0.036). Applying to the prosthodontics clinic during the period when pandemic measures were reduced (OR = 2.158) and the possibility of transmitting COVID-19 to relatives (OR = 1.816), and removing the mask during examination and treatment (OR = 2.245) were factors that increased the risk of anxiety. Applying to the prosthodontics clinic (OR = 2.757), the possibility of transmitting COVID-19 to relatives (OR = 1.653) were factors that increased the risk of depression in participants.</p>\u0000 <p><b>Conclusion:</b> In the third year of the pandemic, we can assume that patients who have not had COVID-19 and were smokers who applied to the prosthodontics clinic are more prone to depression. Also, it can be said that application to the prosthodontics clinic during this period and the worrying about transmitting COVID-19 to relatives are both anxiety and depression-increasing factors. Removing the mask during examination and treatment is an anxiety-increasing factor.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/8888157","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143564917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Diagnoses According to ICD-10 and ICPC-2 in Family Medicine Practice: A Retrospective Study","authors":"Olgun Göktaş","doi":"10.1155/ijcp/7146424","DOIUrl":"https://doi.org/10.1155/ijcp/7146424","url":null,"abstract":"<div>\u0000 <p><b>Introduction:</b> After the International Statistical Classification of Diseases and Related Health Problems, briefly ICD (ICD-10), the World Health Organization (WHO) accepted the International Classification of Primary Care (ICPC-2) as a reason for encounter classification of diagnoses in primary healthcare services. The study aimed to assess the degree of alignment between diagnoses encoded with the ICD-10 and, those coded using the ICPC-2.</p>\u0000 <p><b>Materials and Methods:</b> We collected the diagnoses coded with the ICD-10 of 42,782 patients registered in the Uludağ University Family Health Center, Bursa, Turkey. The ICD-10 codes were converted to ICPC-2 codes with the program in the family medicine information registration system. Diagnoses in the database were analyzed. <i>p</i> values less than 0.05 were considered significant in the study. Analyses were made with the SPSS 25.0 package program.</p>\u0000 <p><b>Results:</b> Of the 42,782 diagnoses with codes in ICD-10, a total of 218 diagnoses (0.51%) did not have an equivalent in ICPC-2. On the other hand, it was determined that a total of 463 diagnoses (1.08%) in ICD-10 had 2 or more codes in ICPC-2.</p>\u0000 <p><b>Conclusion:</b> According to our results in family medicine practice, the equivalents of ICD-10 and ICPC-2 codes were different in number and percentage. It is ideal for individual health and research that the diagnosis codes in family medicine are the same as the codes in other secondary and tertiary care clinics. Since health requires holisticity, we recommend that both classifications be integrated and revised to be globally understandable and provide complementary coding in different clinical applications.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7146424","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Major Etiologies of Male Infertility Among Couples Attending Fertility Clinics in Osun State, Nigeria: Findings From a Mixed-Method Study","authors":"Kehinde Awodele,&nbsp;Sunday Charles Adeyemo,&nbsp;Eniola Dorcas Olabode,&nbsp;Adeniyi Olanipekun Fasanu,&nbsp;Akintunde Rasaq Akindele,&nbsp;Segun Adegboyega Afolabi,&nbsp;Funso Abidemi Olagunju,&nbsp;Olusegun Oyerinde,&nbsp;Lanre Olaitan","doi":"10.1155/ijcp/7884777","DOIUrl":"https://doi.org/10.1155/ijcp/7884777","url":null,"abstract":"<div>\u0000 <p>Male infertility accounts for nearly half of the infertility cases globally. Seminal fluid analysis (SFA) is a critical diagnostic tool in the evaluation of male infertility. This study aimed to assess the implications of SFA on male infertility among patients attending fertility clinics in Osogbo, Nigeria. The study employed a mixed-method approach of both qualitative (key informant interview [KII]) among 10 participants and quantitative methods (cross-sectional survey) using a pretested structured questionnaire among 305 respondents. The respondents in the cross-sectional survey were also made to undergo SFA. The data from the qualitative study were analyzed using ATLAS.ti, while the data from the quantitative study were analyzed using IBM Statistical Product for Service Solution (SPSS) version 27.0. Descriptive statistics was carried out for all variables. The univariate, bivariate, and multivariate analyses were done using <i>p</i> &lt; 0.05 as the level of significance. The SFA of the respondents revealed that 241 (79.0%) had normal sperm counts (&gt; 32 million per ejaculation), while 64 (21.0%) had abnormal sperm counts. Only 101 (33.1%) had sperm cells with normal progressive motility (&gt; 32%), while 204 (66.9%) had abnormal (Athenospermia) progressive motility. One hundred and ninety-five (63.9%) were found to have abnormal morphology (Teratospermia, i.e., &lt; 4%). The analysis of the data from the KII further explained the implications of SFA parameters on infertile males, and these were substantial, extending beyond physical health to encompass psychological, emotional, and social well-being. The study concluded that lifestyle modifications, early diagnosis, and prompt treatment of medical conditions can help reduce the high prevalence of SFA abnormalities and, consequently, decrease male infertility in our environment. This study recommends that advocacy programs, early screening, and public health education will further reduce the burden of infertility among the men.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7884777","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143489926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Role of Plateletcrit in Pleural Effusion","authors":"Burcu Akkok,&nbsp;Fatos Kozanli","doi":"10.1155/ijcp/5553736","DOIUrl":"https://doi.org/10.1155/ijcp/5553736","url":null,"abstract":"<div>\u0000 <p><b>Objectives:</b> Pleural effusion arises from either increased fluid production or reduced absorption within the pleural space. In instances where thoracentesis is contraindicated or unfeasible, alternative, less invasive diagnostic approaches are necessary. Thoracentesis with simultaneous venous blood sampling is pivotal for differentiating transudative from exudative pleural fluid, guided by the Light criteria In instances where thoracentesis is contraindicated or unfeasible, alternative, less invasive diagnostic approaches are necessary. Parameters such as platelet (PLT) count, plateletcrit (PCT), PLT distribution width (PDW), and mean PLT volume (MPV) have been proposed as adjuncts to other acute phase reactants in identifying inflammation activation. This study aims to investigate the feasibility of Plt activation markers in diagnosing pleural effusion.</p>\u0000 <p><b>Methods:</b> This retrospective observational study involved patients diagnosed with pleural effusion who were admitted to hospital between 01 January 2021 and 31 May 2023. Cases where the effusion nature was determined through thoracentesis were included. Among the complete blood count parameters, neutrophil, lymphocyte, Plt count, PCT, PDW and MPV were calculated.</p>\u0000 <p><b>Results:</b> The study encompassed a cohort of 155 cases, comprising 43.2% females and 56.8% males.Thoracentesis revealed 66.5% exudative effusions and 33.5% transudative effusions. PDW and MPV were significantly lower in the exudate group than in the transudate group. PCT values demonstrated significant effectiveness (area under the curve, 0.740 [0.653–0.828]) in distinguishing patients with exudates from those with transudates. A cut-off value of 0.275 for PCT yielded significant effectiveness with a sensitivity of 83.5%, and a specificity of 61.5%. For a PDW cut-off value of 10.5, the sensitivity was 49.5%, and specificity was 75.0%.</p>\u0000 <p><b>Conclusions:</b> The sensitivity and specificity of Plt parameters in differentiating patients in transudate and exudate groups were found to be high.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5553736","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143481485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Iron Accumulation on Bone Mineral Density in Patients Diagnosed With Transfusion-Dependent Thalassemia","authors":"Cem Selim,&nbsp;Rafiye Çiftçiler,&nbsp;Ayşe Hilal Eroğlu Küçükdiler,&nbsp;Fatma Keklik Karadağ,&nbsp;Nur Soyer","doi":"10.1155/ijcp/5411059","DOIUrl":"https://doi.org/10.1155/ijcp/5411059","url":null,"abstract":"<div>\u0000 <p><b>Introduction:</b> Transfusion-dependent thalassemia (TDT) is most commonly caused by defects in beta globin chain production. Iron overload, hypogonadism, vitamin D deficiency, adverse effects of desferrioxamine treatment, and delayed puberty due to loss of bone mass are the main complications of TDT. In the present study, we aimed to investigate bone complications and precursor markers in TDT patients.</p>\u0000 <p><b>Materials and Methods:</b> Our retrospective study included 93 patients, aged between 18 and 45, who were followed up in a tertiary care institution and did not have any disease other than TDT. The patients’ BMD values and biochemical parameters were compared.</p>\u0000 <p><b>Results:</b> Osteoporosis was observed in 33 of 93 patients, and the mean transferrin saturation of patients with osteoporosis was 60%, and the mean transferrin saturation of patients without osteoporosis was 42%. Patients with osteoporosis had transferrin saturation that was observed to be considerably higher than that of the group without osteoporosis (<i>p</i> = 0.006), with an average of 60%.</p>\u0000 <p><b>Conclusion:</b> Our investigation has demonstrated that in patients with TDT, elevated transferrin saturation may be a sign of osteoporosis.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5411059","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143466279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk Factors for Myasthenic Crisis in Patients With Myasthenia Gravis: A Retrospective Study in Southwest China","authors":"Xue Lin,&nbsp;Hongxi Chen,&nbsp;Xiaofei Wang,&nbsp;Ziyan Shi,&nbsp;Rui Wang,&nbsp;Hongyu Zhou","doi":"10.1155/ijcp/9145129","DOIUrl":"https://doi.org/10.1155/ijcp/9145129","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Myasthenic crisis (MC) is a rare but potentially fatal complication that can significantly worsen the prognosis of patients with myasthenia gravis (MG). However, predicting the occurrence of MC remains challenging. Therefore, this study aimed to identify potential risk factors associated with MC.</p>\u0000 <p><b>Methods:</b> A retrospective study was conducted using the MG Cohort Database at the West China Hospital of Sichuan University from January 2004 to August 2023. The multivariate Cox regression analysis was performed to determine the risk factors for MC.</p>\u0000 <p><b>Results:</b> Among the 1150 patients with MG included in the final analysis, 128 (11.1%) experienced at least one episode of MC. Independent risk factors identified for MC included age (hazard ratio [HR]: 1.02, 95% confidence interval [CI]: 1.01–1.03, <i>p</i> &lt; 0.001), quantitative MG (QMG) score (HR: 1.04, 95% CI: 1.01–1.07, <i>p</i> = 0.003), MG Foundation of America (MGFA) class at diagnosis (HR: 3.19, 95% CI: 2.38–4.28, <i>p</i> &lt; 0.001), and the presence of thymoma (HR: 3.21, 95% CI: 2.13–4.85, <i>p</i> &lt; 0.001). In contrast, generalized MG (<i>p</i> = 0.891) and the presence of antimuscle-specific tyrosine kinase (MuSK) antibodies (<i>p</i> = 0.107) did not significantly increase the risk of developing MC.</p>\u0000 <p><b>Conclusion:</b> Age, disease severity as indicated by the QMG score and MGFA class at diagnosis, along with thymoma presence were identified as potential predictors for MC in patients diagnosed with MG.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9145129","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143431680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Hand Edema on Weaning From Mechanical Ventilation in ICU Patients: A Single Center Nested Case-Control Study","authors":"Dingye Wu,&nbsp;Junfeng Heng,&nbsp;Fengming Liang,&nbsp;Tao Zhou,&nbsp;Qiuhui Wang,&nbsp;Hongyang Xu","doi":"10.1155/ijcp/7382862","DOIUrl":"https://doi.org/10.1155/ijcp/7382862","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To investigate the impact of hand edema on weaning from mechanical ventilation among ICU patients.</p>\u0000 <p><b>Methods:</b> A nested case-control study was conducted, collecting data from mechanically ventilated patients admitted to the ICU of Wuxi People’s Hospital from October 1, 2023, to January 31, 2024. Patients were monitored for the occurrence of hand edema within the first 7 days of ICU stay and their weaning outcomes were recorded to analyze the impact of hand edema on weaning success.</p>\u0000 <p><b>Results:</b> The study included 124 patients, 97 successfully weaned while 27 failed. The failed weaning group had higher ages (70.8 ± 10.5 years), SOFA scores (17.7 ± 3.1), and levels of hand edema (Grade 0 in 6 patients, Grade 1 in 9, Grade 2 in 6, Grade 3 in 3, and Grade 4 in 3) compared with the successful weaning group (ages 61.1 ± 9.8 years, SOFA scores 14.3 ± 3.1, hand edema levels: Grade 0 in 78, Grade 1 in 15, Grade 2 in 3, Grade 3 in 1, and Grade 4 in 0). Multivariable binary logistic regression analysis indicated that the level of hand edema is an independent risk factor for weaning failure within 1 week in ICU patients on mechanical ventilation (OR = 3.209, 95% CI: 1.641–6.274, and <i>p</i> &lt; 0.05).</p>\u0000 <p><b>Conclusion:</b> The occurrence of hand edema in ICU patients on mechanical ventilation increases the risk of weaning failure.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7382862","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143424112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Effect of Stress Ball Utilization on Dyspnea Severity and Anxiety Level in Patients Receiving Nebulizer Therapy: Randomized Controlled Study","authors":"Yasemin Ceyhan,&nbsp;Sevil Güler,&nbsp;Seda Şahan","doi":"10.1155/ijcp/9770027","DOIUrl":"https://doi.org/10.1155/ijcp/9770027","url":null,"abstract":"<div>\u0000 <p><b>Aim:</b> The study primarily aimed at examining the effect of stress ball utilization on dyspnea and anxiety during nebulizer therapy. The secondary aim was to determine the effect of stress ball utilization on the duration of therapy and vital signs.</p>\u0000 <p><b>Methods:</b> The study has a randomized controlled experimental design. The study population consisted of inpatients receiving nebulizer therapy. A total of 80 patients, 40 in the intervention group and 40 in the control group, were included in the sample. The study was conducted between October 2023 and March 2024. Patients in the intervention group were asked to use a stress ball during nebulizer therapy. Data were collected using a Patient Information Form, the Visual Analog Scale, and the State-Trait Anxiety Inventory. Descriptive statistics, Chi-square, paired test, and one sample <i>t</i>-test were used in data analysis.</p>\u0000 <p><b>Results:</b> The mean age of the patients was 65 years and over and 78% of them had COPD. Stress ball utilization caused a significant effect on the severity of dyspnea (intervention: <i>t</i> = 2.862, <i>p</i> &lt;  0.001; control: <i>t</i> = 2.755, <i>p</i> &lt; 0.001) and anxiety levels (intervention: <i>t</i> = 4.647, <i>p</i> &lt; 0.001; control: <i>t</i> = 6.597, <i>p</i> &lt; 0.001) in intragroup comparisons. In intergroup comparisons, a significant difference (<i>t</i>^<i>ı</i> = 4.455, <i>p</i> &lt; 0.001) was obtained in anxiety level with a high effect (<i>d</i> = 0.70). In addition, the durations of nebulizer (minutes) administration were significantly (<i>p</i> &lt; 0.001) longer in the intervention group (19.10 ± 11.95) than in the control group (13.16 ± 3.02). Stress ball utilization did not affect vital signs and saturation values (<i>p</i> &gt; 0.05).</p>\u0000 <p><b>Conclusions:</b> Utilization of a stress ball during nebulizer therapy has a positive effect on reducing anxiety levels and prolonging the duration of nebulizer use.</p>\u0000 <p><b>Trial Registration:</b> ClinicalTrials.gov identifier: NCT06297356</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-02-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9770027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423828","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}