International Journal of Clinical Practice最新文献

{"title":"Effectiveness of ReCOVery APP to Improve the Quality of Life of Long COVID Patients: A 6-Month Follow-Up Randomized Clinical Trial","authors":"Sandra León-Herrera,&nbsp;Mario Samper-Pardo,&nbsp;Bárbara Oliván-Blázquez,&nbsp;Rosa Magallón-Botaya,&nbsp;Verónica Casado-Vicente,&nbsp;Raquel Sánchez-Recio,&nbsp;Rafael Sánchez-Arizcuren","doi":"10.1155/ijcp/7692776","DOIUrl":"https://doi.org/10.1155/ijcp/7692776","url":null,"abstract":"<div>\u0000 <p><b>Purpose:</b> This study aims to analyze the medium-term effectiveness of telerehabilitation in enhancing the quality of life for patients with Long COVID, using a mobile application (APP) called ReCOVery APP. The secondary purpose is to identify significant factors associated with an improvement in the quality of life and other secondary outcomes in this population.</p>\u0000 <p><b>Methods:</b> A randomized clinical trial was carried out with two parallel groups involving a total of 100 patients with Long COVID. The first one (control group, <i>n</i> = 48) continued with their usual treatment (TAU), established by their primary care doctor. The second one (intervention group, <i>n</i> = 52), in addition to continuing with their TAU, attended three sessions based on motivational methodology and used the ReCOVery APP for 6 months. The primary outcome was quality of life.</p>\u0000 <p><b>Results:</b> After 6 months, ReCOVery APP did not significantly improve the quality of life among Long COVID patients. Poor adherence to the APP was observed among the participants who tried it. Linear regression analyses revealed a significant relationship between the decrease in the number of symptoms and the improvement in mental health–related quality.</p>\u0000 <p><b>Conclusions:</b> While this research contributes valuable insights into the potential of telerehabilitation for Long COVID patients, the lack of significant improvement in quality of life underscores the need for future large-scale studies. Such research should focus on identifying effective strategies to enhance adherence to digital interventions, such as increased professional support and personalized care approaches. Additionally, exploring the long-term effects of telerehabilitation could provide a more comprehensive understanding of its role in managing Long COVID.</p>\u0000 <p><b>Trial Registration:</b> ISRCTN Registry identifier: ISRCTN91104012</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7692776","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cognitive Fusion Versus Software Fusion for Subcentimeter Lesions in Transperineal mpMRI/TRUS Fusion-Guided Prostate Biopsy Under Local Anesthesia","authors":"Hejia Yuan,&nbsp;Peng Peng,&nbsp;Fan Feng,&nbsp;Yining Zhao,&nbsp;Yantao Lou,&nbsp;Jipeng Wang,&nbsp;Hongwei Zhao,&nbsp;Jitao Wu","doi":"10.1155/ijcp/5003501","DOIUrl":"https://doi.org/10.1155/ijcp/5003501","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> The accuracy debate between cognitive and software fusion for small lesions in multiparametric magnetic resonance imaging (mpMRI)/transrectal ultrasound (TRUS) fusion-guided prostate biopsy remains inconclusive. This study compares the diagnostic accuracy of these fusion methods for prostate cancer, specifically for lesions &lt; 1 cm under local anesthesia.</p>\u0000 <p><b>Methods:</b> Retrospective analysis of prostate biopsies performed at The Affiliated Yantai Yuhuangding Hospital of Qingdao University (Feb 16, 2019–Feb 16, 2023). The Cognitive Fusion Group used free-hand technique for mentally integrating mpMRI and TRUS fusion, while the Software Fusion Group used MIM software with a fusion guidance grid. Lesions were defined as &lt; 1 cm of maximum diameter on coronal using mpMRI. Each patient underwent 2–4 targeted biopsies for the identified lesion, followed by 12 systematic biopsies. All biopsies were transperineal and performed under local anesthesia.</p>\u0000 <p><b>Results:</b> Histology showed clinically significant prostate cancer (International Society of Urological Pathology ≥ 2) in 55 cases (42.6%) in the software fusion group and 66 cases (40.2%) in the cognitive fusion group within the targeted prostate cancer category. However, cognitive fusion had a shorter median operative time of 11 min compared to 22 min in the software fusion group. Complication rates did not significantly differ between the two fusion strategies.</p>\u0000 <p><b>Conclusion:</b> This study suggests that experienced operators can achieve comparable diagnostic accuracy for sub-centimeter lesions in mpMRI/TRUS fusion-guided prostate biopsy using cognitive fusion. Furthermore, cognitive fusion offers simplicity and shorter procedural time. These findings contribute to the discourse on fusion methods in prostate cancer diagnosis, and further validation studies are warranted.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5003501","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cardiovascular Disease Management and Prevention in Saudi Arabia: Strategies, Risk Factors, and Targeted Interventions","authors":"Aseel Awad Alsaidan","doi":"10.1155/ijcp/7233591","DOIUrl":"https://doi.org/10.1155/ijcp/7233591","url":null,"abstract":"<div>\u0000 <p>Cardiovascular diseases (CVDs) remain the main cause of mortality and are generally among the leading causes of morbidity worldwide, thus placing an immense burden on health care. They include coronary artery disease, heart failure, hypertensive heart disease, and stroke. Among these, common risk factors include hypertension, high cholesterol, diabetes, smoking, obesity, and sedentary lifestyle. Yet, with advancements in medical science and pharmacology, these entities remain major challenges to public health worldwide. In Saudi Arabia, the rise in CVDs has been intensified by rapid urbanization and lifestyle changes and needs unique and tailored public health strategies. This review provides a comprehensive overview of the current situation with regard to cardiovascular health in Saudi Arabia, underlining the need for studying CVDs within the local context. It reviews the epidemiology of CVDs in the Kingdom of Saudi Arabia, outlining some of the major risk factors and also their impact on public health. This study also deals with the pharmacological approaches toward cardiovascular health by offering data from clinical trials so far completed, to point out effective strategies of treatment. The overview of prevention methods also includes public health initiatives, lifestyle programs, patient education, healthcare policies, the role of government initiatives, insurance coverage, and international collaborations. The review also elucidates the problems and barriers of the Saudi healthcare system, especially vis-à-vis the primary healthcare setting. In light of improving its healthcare sector, Saudi Arabia has embarked on several reforms within the Universal Health Coverage development initiative set in the framework of Vision 2030.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7233591","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy Outcomes After Higher-Order Multifetal Pregnancy Reduction: A Retrospective Study","authors":"Mengjie Fan,&nbsp;Li Li,&nbsp;Yanyi Li,&nbsp;Liying Wang,&nbsp;Hongxia Zhang,&nbsp;Shuo Yang,&nbsp;Jia Li,&nbsp;Ying Song,&nbsp;Di Sun,&nbsp;Danlei Zheng,&nbsp;Tian Tian,&nbsp;Caihong Ma,&nbsp;Ping Liu,&nbsp;Jie Qiao,&nbsp;Rui Yang,&nbsp;Rong Li","doi":"10.1155/ijcp/2512443","DOIUrl":"https://doi.org/10.1155/ijcp/2512443","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To investigate the pregnancy outcomes after transvaginal or transabdominal fetal reduction for higher-order multifetal pregnancies with four or more fetuses.</p>\u0000 <p><b>Methods:</b> This retrospective study included 102 patients with higher-order multifetal pregnancies after ovulation induction. The patients underwent fetal reduction in the Reproductive Medical Center of Peking University Third Hospital from January 2000 to December 2020. Methods of fetal reduction included transvaginal and transabdominal reduction. Pregnancy outcomes of different methods were assessed, including the live birth rate, miscarriage rate, preterm labor rate, and low birthweight rate.</p>\u0000 <p><b>Results:</b> Among these 102 patients, 84 (82.4%) underwent transvaginal fetal reduction in early pregnancy, and 18 (17.6%) underwent transabdominal reduction in the second trimester. The live birth rate (66% vs. 78%, <i>p</i> = 0.311), preterm labor rate (24% vs. 33%, <i>p</i> = 0.587), and miscarriage rate (25% vs. 17%, <i>p</i> = 0.653) were comparable for transvaginal and transabdominal fetal reduction. Age, the method of fetal reduction, and the initial number and retained number of fetuses were not influencing factors of the live birth rate or miscarriage rate in these patients.</p>\u0000 <p><b>Conclusion:</b> Prevention is the most important measure to decrease the incidence of multiple pregnancies. For higher-order multifetal pregnancies, multifetal pregnancy reduction (MFPR) is considered a significant remedial measure. Transvaginal fetal reduction in the first trimester of pregnancy and transabdominal fetal reduction in the second trimester were both safe and effective.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/2512443","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Development and Psychometric Validation of Culture of Patient Safety Scale Under Rasch Objective Measurement Theory","authors":"Odunayo Kolawole Omolade,&nbsp;John Stephenson","doi":"10.1155/ijcp/9997682","DOIUrl":"https://doi.org/10.1155/ijcp/9997682","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Assessing the culture of patient safety in healthcare settings is pivotal for continuously reinforcing effective, safe and quality patient care. However, most of the rating scales lack evidence of objective validation of the measuring instruments.</p>\u0000 <p><b>Aim:</b> To determine the psychometric properties of culture of patient safety scale under the Rasch objective measurement theory.</p>\u0000 <p><b>Method:</b> The validation of the culture of safety scale was underpinned by the four stages of rating scale development in Rasch objective measurement theory. The first stage involved literature review to shortlist items considered theoretically relevant to culture of patient safety in hospital settings. In the second stage, a panel of academic and practitioners individually reviewed the selected items to give external face validity based on professional experiences. In the third stage, 967 participants from public maternity settings in Nigeria voluntarily accessed the nine items forming the culture of patient safety scale online over 8-week period. Ethical approval was given by the nurses’ association and University of Huddersfield. Subsequently, all the data were exported to SPSS and Winsteps Version 5.0.0.0 for evaluation of the psychometric assumptions. Essential psychometric properties evaluated are dimensionality, category functioning, item difficulty/agreeability, local independence, reliability and item validity. In the fourth stage, problematic items were identified and moderated based on the outcome of the measurement assumptions. Consequently, final decisions made included retention, modification or expulsion of items, making no meaningful contribution to the variable measurement.</p>\u0000 <p><b>Conclusion and Implication:</b> The culture of safety scale has excellent psychometric properties and therefore recommended for use among practitioners and researchers. No direct contribution from the public or patients required in this study.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9997682","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ultrasonographic Measurements of Femoral Cartilage Thickness in Women With Symptomatic Joint Hypermobility: A Controlled Study","authors":"Tuğçe Yavuz Mollavelioğlu,&nbsp;Nurdan Paker,&nbsp;İlhan Karacan,&nbsp;Levent Özçakar","doi":"10.1155/ijcp/9615146","DOIUrl":"https://doi.org/10.1155/ijcp/9615146","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> The goal of this study was to measure femoral cartilage thickness in patients with symptomatic joint hypermobility (SJH) using ultrasound (US) imaging.</p>\u0000 <p><b>Methods:</b> This cross-sectional study comprised 42 female patients diagnosed with SJH (Beighton score &gt; 3) and 42 age-matched healthy controls. Ultrasonographic measurements of bilateral femoral cartilage thickness were conducted in three areas: medial, intercondylar, and lateral, while the patients were in a supine position with their knees fully flexed. The Numeric Pain Rating Scale and the Turkish version of the Knee Injury and Osteoarthritis Outcome Score were used to evaluate pain and functional status in the SJH group.</p>\u0000 <p><b>Results:</b> The mean age was 28.0 ± 7.1 years in the study group and 28.5 ± 7.2 years in the control group. The right medial, left medial, left intercondylar, and left lateral femoral cartilage thicknesses of patients in the SJH group were significantly thinner than those of patients in the control group (<i>p</i> &lt; 0.05). There was no significant difference in femoral cartilage thickness, pain, and functional scores between patients with and without knee hypermobility within the SJH group (<i>p</i> &gt; 0.05). A negative correlation was observed between femoral cartilage thickness and age, which was identified as an independent predictor of femoral cartilage thickness in SJH (<i>p</i> &lt; 0.05).</p>\u0000 <p><b>Conclusion:</b> Femoral cartilage thickness was significantly reduced on the right/left medial, left intercondylar, and left lateral sides in women with SJH compared to healthy subjects. Furthermore, age appears to be an important determinant of femoral cartilage thickness.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9615146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Comparative Analysis of the Gut Microbiota in Patients With Parkinson’s Disease Worldwide: A Systematic Review","authors":"Mira Beisembayeva,&nbsp;Yelena Shayakhmetova,&nbsp;Shynar Muratbekova,&nbsp;Irina Li,&nbsp;Eduard Yakupov,&nbsp;Rauan Kaiyrzhanov,&nbsp;Marina Grigolashvili","doi":"10.1155/ijcp/5511146","DOIUrl":"https://doi.org/10.1155/ijcp/5511146","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Parkinson’s disease (PD) is a neurodegenerative disease associated with the gut microbiome.</p>\u0000 <p><b>Objective:</b> Conducting a comparative analysis of the intestinal microbiome in PD patients from different geographical regions.</p>\u0000 <p><b>Methods:</b> Two researchers conducted a systematic literature review of the Web of Science, PubMed, and Scopus databases, using specific search terms and defined inclusion and exclusion criteria to select studies. This is the first systematic review that conducted an analysis of the gut microbiota of PD patients from all continents.</p>\u0000 <p><b>Results:</b> The α-diversity of PD patients does not differ significantly from healthy individuals in Europe and America, in contrast to Asia and Australia. β-Diversity varies among PD patients in different continents. In all regions, there has been an increase in <i>Proteobacteria</i> and Lactobacillaceae and a decrease in Lachnospiraceae and <i>Roseburia</i>. In Europe, Asia, and America, PD patients have shown an increase in Bifidobacteriaceae, <i>Desulfovibrio</i>, <i>Verrucomicrobia, Bilophila</i>, and <i>Akkermansia</i> and a decrease in <i>Lachnospira</i>. In Asia, America, and Australia, there has been a decrease in <i>Fusicatenibacter</i> and Lachnospiraceae <i>ND3007</i>, while in Europe, America, and Australia, there has been a reduction in <i>Butyricicoccus</i>.</p>\u0000 <p><b>Conclusions</b>: There were no consistent patterns in the changes in α- and β-diversities of the gut microbiota among PD worldwide. Across all continents, there was an increase in <i>Proteobacteria</i> and Lactobacillaceae and a decrease in Lachnospiraceae and <i>Roseburia</i>. Despite these similar trends, there were also differences that may be attributed to factors such as ethnic background, geography, and dietary habits. These differences suggest that individualized approaches to treatment may be necessary to effectively manage PD-related gastrointestinal symptoms.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5511146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Synergistic Impact of 25-Hydroxyvitamin D Level and Obesity on the Risk of Metabolic Syndrome","authors":"Tsui-Yen Chang,&nbsp;Jong-Dar Chen","doi":"10.1155/ijcp/6634233","DOIUrl":"https://doi.org/10.1155/ijcp/6634233","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> The global increase in the prevalence of metabolic syndrome (MetS), which is defined by impaired glucose homeostasis, visceral obesity, hypertension, and dyslipidemia, presents a significant health concern. Obesity is a primary risk factor for MetS, and low vitamin D levels have been linked to several metabolic disorders. Given the high prevalence of vitamin D deficiency among individuals with obesity, this study examined the combined influence of vitamin D deficiency and obesity on the risk of MetS.</p>\u0000 <p><b>Methods:</b> This cross-sectional study was conducted from January 2021 to December 2022 at Shin Kong Memorial Hospital. A total of 7248 participants underwent physical examinations, including measurements of fasting glucose levels, lipid profiles, and serum 25-hydroxyvitamin D levels. Participants were categorized into six groups according to vitamin D status (deficiency &lt; 50 nmol/L, insufficiency 50–74.9 nmol/L, and sufficiency ≥ 75 nmol/L) and body mass index (BMI; nonobese &lt; 27 kg/m² and obese ≥ 27 kg/m²).</p>\u0000 <p><b>Results:</b> Vitamin D levels were significantly lower in younger patients, women, those with BMI ≥ 27 kg/m², and those who engaged in exercise less frequently. Patients with vitamin D sufficiency and without obesity constituted the reference group. Vitamin D level was inversely associated with MetS (odds ratio [OR] = 1.7 and 95% confidence interval [CI]: 1.4–2.0), with a stronger association in individuals with obesity (OR = 9.2 and 95% CI: 7.9–10.7). The highest risk was observed in patients with both vitamin D deficiency and obesity (OR = 13.7). Vitamin D deficiency and obesity were found to synergistically influence MetS (synergy index: 1.3 and 95% CI: 1.0–1.7). Notably, the association between vitamin D deficiency and MetS was nonsignificant in patients without obesity.</p>\u0000 <p><b>Conclusions:</b> Both vitamin D deficiency and obesity are independently associated with MetS, with a synergistic effect observed when both conditions are present.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/6634233","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Focus on Visceral Fat Screening in Nonobese Patients With Type 2 Diabetes to Prevent Nonalcoholic Fatty Liver","authors":"Wei-hua Sun,&nbsp;Lu-lu Yang,&nbsp;Chen-chen Wu,&nbsp;Wen-di Zhao,&nbsp;Li Xue","doi":"10.1155/ijcp/4278518","DOIUrl":"https://doi.org/10.1155/ijcp/4278518","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To identify risk factors associated with nonalcoholic fatty liver disease (NAFLD) in patients with type 2 diabetes (T2DM) and provide a basis for improved prevention and treatment strategies for NAFLD.</p>\u0000 <p><b>Methods:</b> A total of 156 hospitalized patients with T2DM were enrolled and divided into NAFLD and non-NAFLD groups (75 and 81 patients, respectively) based on the ultrasonic diagnosis results. Biochemical data were collected from all patients. A bioelectrical impedance analyzer (OMRON, HDS-2000 DUALSCANR) was used to analyze visceral adipose tissue (VAT) and subcutaneous adipose tissue (SAT) in the abdomen. Statistical analyses were conducted using SPSS 22.0 software.</p>\u0000 <p><b>Results:</b> Statistically significant differences were observed between the NAFLD and non-NAFLD groups in body weight, body mass index (BMI), waist and hip circumference (WC and HC), waist-to-hip ratio (WHR), fasting C-peptide (FCP), alanine aminotransferase (ALT), gamma-glutamyl transpeptidase (GGT), total triglycerides (TG), high-density lipoprotein cholesterol (HDL-C), apolipoprotein B (apoB), superoxide dismutase (SOD), free fatty acids (FFA), VAT, and SAT (all <i>p</i> &lt; 0.05). VAT was positively correlated with BMI (<i>r = </i>0.703, <i>p</i> &lt; 0.001), WC (<i>r = </i>0.685, <i>p</i> &lt; 0.001), HC (<i>r = </i>0.547, <i>p</i> &lt; 0.001), SAT (<i>r = </i>0.774, <i>p</i> &lt; 0.001), TG (<i>r = </i>0.365, <i>p</i> &lt; 0.001), FCP (<i>r = </i>0.287, <i>p</i> &lt; 0.001), ALT (<i>r = </i>0.282, <i>p</i> &lt; 0.001), and GGT (<i>r = </i>0.273, <i>p</i> = 0.001) and negatively correlated with HDL-C (<i>r = </i>−0.201, <i>p</i> = 0.012). Multivariable logistic regression analysis indicated that VAT and FFA are independent influencing factors for NAFLD (<i>p</i> &lt; 0.01). A receiver operating characteristic curve showed that the sensitivity and specificity of VAT for predicting NAFLD in T2DM were 88.0% and 57.8%, respectively.</p>\u0000 <p><b>Conclusions:</b> VAT and FFA are independent risk factors for NAFLD in patients with T2DM, with VAT serving as a reliable predictor for NAFLD screening. Screening for NAFLD should not be limited to overweight or obese individuals; attention should also be given to nonobese and lean patients.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/4278518","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomogram for Prediction of Isolated Calf Deep Vein Thrombosis in Internal Medicine Patients","authors":"Yutao Wang,&nbsp;Xue Pang,&nbsp;Ming Liu","doi":"10.1155/ijcp/2015063","DOIUrl":"https://doi.org/10.1155/ijcp/2015063","url":null,"abstract":"<div>\u0000 <p>This study aims to construct a nomogram anticipating the occurrence of isolated calf deep vein thrombosis (ICDVT), specifically in patients receiving internal medicine care. This case-control study enrolled 610 internal medicine patients admitted to the Jinan Municipal Hospital of Traditional Chinese Medicine between December 2019 and July 2022. Of the total number of patients who participated in the study, 147 were assigned to the ICDVT group, whereas 463 were assigned to the non-ICDVT group. The least absolute shrinkage and selection operator (LASSO) regression was employed to perform feature selection. A prediction model was constructed using a multivariable logistic regression analysis. The validity and practicality of the nomogram were assessed using several statistical measures, including concordance index (C-index), receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA). Gender, age, D-dimer, and diabetes mellitus were correlated with the presence of ICDVT in the considered internal medicine patients. The predictive nomogram revealed acceptable performance with a C-index of 0.883 (95% confidence interval [CI]: 0.822–0.914) in the internal verification. The area under the ROC curve was 0.883 (95% CI: 0.853–0.914), and the Hosmer–Lemeshow goodness-of-fit <i>p</i> value was 0.888. DCA findings indicated that the ICDVT nomogram exhibited a favorable clinical net benefit. The created nomogram has the potential to help clinicians identify high-risk groups of ICDVT among patients in the field of internal medicine, thus enabling early intervention strategies.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/2015063","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143629823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}