Nomogram for Prediction of Isolated Calf Deep Vein Thrombosis in Internal Medicine Patients

IF 2.2 4区 医学 Q2 MEDICINE, GENERAL & INTERNAL
Yutao Wang, Xue Pang, Ming Liu
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Abstract

This study aims to construct a nomogram anticipating the occurrence of isolated calf deep vein thrombosis (ICDVT), specifically in patients receiving internal medicine care. This case-control study enrolled 610 internal medicine patients admitted to the Jinan Municipal Hospital of Traditional Chinese Medicine between December 2019 and July 2022. Of the total number of patients who participated in the study, 147 were assigned to the ICDVT group, whereas 463 were assigned to the non-ICDVT group. The least absolute shrinkage and selection operator (LASSO) regression was employed to perform feature selection. A prediction model was constructed using a multivariable logistic regression analysis. The validity and practicality of the nomogram were assessed using several statistical measures, including concordance index (C-index), receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA). Gender, age, D-dimer, and diabetes mellitus were correlated with the presence of ICDVT in the considered internal medicine patients. The predictive nomogram revealed acceptable performance with a C-index of 0.883 (95% confidence interval [CI]: 0.822–0.914) in the internal verification. The area under the ROC curve was 0.883 (95% CI: 0.853–0.914), and the Hosmer–Lemeshow goodness-of-fit p value was 0.888. DCA findings indicated that the ICDVT nomogram exhibited a favorable clinical net benefit. The created nomogram has the potential to help clinicians identify high-risk groups of ICDVT among patients in the field of internal medicine, thus enabling early intervention strategies.

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来源期刊
CiteScore
5.30
自引率
0.00%
发文量
274
审稿时长
3-8 weeks
期刊介绍: IJCP is a general medical journal. IJCP gives special priority to work that has international appeal. IJCP publishes: Editorials. IJCP Editorials are commissioned. [Peer reviewed at the editor''s discretion] Perspectives. Most IJCP Perspectives are commissioned. Example. [Peer reviewed at the editor''s discretion] Study design and interpretation. Example. [Always peer reviewed] Original data from clinical investigations. In particular: Primary research papers from RCTs, observational studies, epidemiological studies; pre-specified sub-analyses; pooled analyses. [Always peer reviewed] Meta-analyses. [Always peer reviewed] Systematic reviews. From October 2009, special priority will be given to systematic reviews. [Always peer reviewed] Non-systematic/narrative reviews. From October 2009, reviews that are not systematic will be considered only if they include a discrete Methods section that must explicitly describe the authors'' approach. Special priority will, however, be given to systematic reviews. [Always peer reviewed] ''How to…'' papers. Example. [Always peer reviewed] Consensus statements. [Always peer reviewed] Short reports. [Always peer reviewed] Letters. [Peer reviewed at the editor''s discretion] International scope IJCP publishes work from investigators globally. Around 30% of IJCP articles list an author from the UK. Around 30% of IJCP articles list an author from the USA or Canada. Around 45% of IJCP articles list an author from a European country that is not the UK. Around 15% of articles published in IJCP list an author from a country in the Asia-Pacific region.
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