Md. Asaduzzaman, Mohammad Romel Bhuia, Mohammad Zabed Jillul Bari, Z. H. M. Nazmul Alam, Ranjon Kumer Roy, Soumitra Roy, Goutam Talukder, M. M. Jahangir Alam, Md. Shafiqul Bari
{"title":"Exploring Prognostic Markers for Patients With COVID-19 in a Low-Resource Setting: A Cross-Sectional Study","authors":"Md. Asaduzzaman, Mohammad Romel Bhuia, Mohammad Zabed Jillul Bari, Z. H. M. Nazmul Alam, Ranjon Kumer Roy, Soumitra Roy, Goutam Talukder, M. M. Jahangir Alam, Md. Shafiqul Bari","doi":"10.1155/ijcp/5595869","DOIUrl":"https://doi.org/10.1155/ijcp/5595869","url":null,"abstract":"<div>\u0000 <p><b>Aim:</b> Triaging patients based on prognostic biomarkers may contribute to better management of at-risk patients in resource-constrained settings. This study aimed to explore readily available and cost-effective predictors of mortality among COVID-19 patients.</p>\u0000 <p><b>Methods:</b> This cross-sectional study, conducted across multiple centers, involved patients with COVID-19 admitted to four hospitals in Bangladesh. The analysis encompassed demographic information, clinical features, laboratory findings, and in-hospital outcomes. Logistic regression was utilized to identify factors contributing to mortality risk.</p>\u0000 <p><b>Results:</b> Among 442 patients, 55 (12.44%) experienced mortality. The patients’ mean was 60 ± 14 years. DM (76% vs. 62%), IHD (42% vs. 19%), CKD (35% vs. 15%), and COPD (24% vs. 11%) were the most prevalent comorbidities in nonsurvivors. Compared to the survivor group, median NLR (7 vs. 4.1; <i>p</i> = 0.005), ferritin (507 vs. 328; <i>p</i> = 0.21), and D-dimer (900 vs. 567; <i>p</i> = 0.12) were higher in the nonsurvivor group. Higher age (OR = 1.05; 95% CI = 1.02–1.08), coexisting CKD (OR = 2.59; 95% CI = 1.27–5.29), leukocytosis (OR = 2.52; 95% CI = 1.21–5.28), thrombocytopenia (OR = 0.27; 95% CI = 0.12–0.61), lower SpO2 upon admission (OR = 0.92; 95% CI = 0.89–0.95), and more extensive lung involvement on CT (OR = 1.01; 95% CI = 1.001–1.03) were significant risk factors of in-hospital death.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5595869","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zihan Zhang, Li Zhang, Yanyu Sun, Rongrong Huo, Yanyue Tan, Fan He, Jun Wang, Shufang Du, Xin Xiong
{"title":"Connection Between Oral Behaviors and Pain Intensity in Temporomandibular Disorder Patients Undergoing Orthodontic Treatment: A Cross-Sectional Study","authors":"Zihan Zhang, Li Zhang, Yanyu Sun, Rongrong Huo, Yanyue Tan, Fan He, Jun Wang, Shufang Du, Xin Xiong","doi":"10.1155/ijcp/9092053","DOIUrl":"https://doi.org/10.1155/ijcp/9092053","url":null,"abstract":"<div>\u0000 <p>Proper management of painful temporomandibular disorders (PTMDs) is important for guaranteeing optimal orthodontic outcomes. Although correlations between oral behaviors and PTMDs have been confirmed in the general population, there is limited corresponding research within the orthodontic patients. The purpose of this cross-sectional study was to examine how pain intensity correlates with the frequency of various oral behaviors in orthodontic patients. Participants completed a questionnaire survey containing demographic details, an eight-item oral behaviors checklist, the five major temporomandibular disorders symptoms (5Ts) checklist, and a visual analog scale (VAS) to gauge pain intensity. Participants were divided into two groups: PTMD and without PTMD (NPT). The correlation between specific oral behaviors and pain intensity was assessed using both univariate and multivariate linear regression analyses, with adjustment for demographic variables such as age, gender, systemic diseases, and level of education. The study gathered 267 valid questionnaires, showing a prevalence of 59.93% for PTMD. In comparison to the NPT group, the PTMD group exhibited a higher frequency of oral behaviors. Significant correlations were identified between various oral behaviors and pain intensity. Univariate and multivariate linear regression analyses demonstrated positive relationships between pain and oral behaviors. After adjusting for demographic variables, these connections remained statistically significant in the multivariate analysis for sleep bruxism (<i>β</i> = 0.17; 95% CI 0.03, 0.31; <i>p</i> = 0.0175), sleep position pressuring jaw (<i>β</i> = 0.15; 95% CI 0.03, 0.26; <i>p</i> = 0.0118), awake bruxism (<i>β</i> = 0.57; 95% CI 0.26, 0.88; <i>p</i> = 0.0004), and holding, tightening, or tensing muscle without clenching (<i>β</i> = 0.18; 95% CI 0.01, 0.36; <i>p</i> = 0.0415). A significant association was identified between the frequency of oral behaviors and pain intensity in orthodontic patients. Screening and management of oral behaviors might be crucial for controlling TMDs during orthodontic treatment.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9092053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143875615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jie Kang, Yi Hang, Zheng Liu, Man Yuan, Xiaosong Qiu, Ying Ye, Yuzhu Zang, Xiaobo Huang, Siyuan Song, Yi Wang
{"title":"Analysis of Pathogenic Bacteria and Associated Risk Factors of Bloodstream Infections in ICU Patients Undergoing ECMO Support Using mNGS Technology","authors":"Jie Kang, Yi Hang, Zheng Liu, Man Yuan, Xiaosong Qiu, Ying Ye, Yuzhu Zang, Xiaobo Huang, Siyuan Song, Yi Wang","doi":"10.1155/ijcp/4985868","DOIUrl":"https://doi.org/10.1155/ijcp/4985868","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To analyze the characteristics of pathogens and related risk factors of bloodstream infections (BSI) in patients undergoing ECMO support using mNGS technology.</p>\u0000 <p><b>Methods:</b> A retrospective analysis was conducted on 59 patients who received ECMO support in the Emergency Intensive Care Unit (EICU) of the Affiliated Hospital of Xuzhou Medical University from January 2021 to March 2024. The patients were divided into two groups based on the presence of BSI: the infection group (BSI group) and the noninfection group (N-BSI group). The clinical data of the two groups were compared, and the characteristics of pathogens were analyzed using mNGS technology. Logistic regression was used to analyze the related risk factors for BSI associated with ECMO.</p>\u0000 <p><b>Results:</b> (1) The incidence of BSI in patients undergoing ECMO support was 20.34%. Compared to the N-BSI group, the BSI group had significantly higher levels of procalcitonin (14.9 ± 7.2 vs. 9.4 ± 4.7), C-reactive protein (140.58 ± 24.64 vs. 87.26 ± 11.06), blood lactate (8.55 ± 1.40 vs. 5.07 ± 0.55), and ECMO catheter indwelling time (12.00 ± 1.71 vs. 7.96 ± 0.76) (<i>p</i> < 0.05). (2) mNGS detection indicated that the BSI group mainly identified viruses and Gram-negative bacilli (G-), with <i>Acinetobacter baumannii</i> being the most prevalent pathogen. The resistance genes were predominantly blaTEM, which confers resistance to penicillins and cephalosporins. (3) Logistic regression analysis revealed that diabetes, ECMO indwelling time, blood lactate levels, and G-bacilli infection were risk factors for BSI during ECMO.</p>\u0000 <p><b>Conclusion:</b> Gram-negative bacteria are the primary pathogens in BSI among patients undergoing ECMO support. Diabetes, ECMO catheter indwelling time, and elevated blood lactate are independent risk factors for these infections. Rational selection of antibiotics and strengthened management of related factors can effectively control the occurrence of BSI during ECMO support.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/4985868","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143865958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yaser Alikhajeh, Roghayyeh Afroundeh, Mohamad Motevalli, Gholam Rasul Mohammad Rahimi, Ozkan Isik
{"title":"The Effect of a Three-Month Aquatic Training Program on Physical Functioning in Elderly Men: A Randomized Controlled Trial","authors":"Yaser Alikhajeh, Roghayyeh Afroundeh, Mohamad Motevalli, Gholam Rasul Mohammad Rahimi, Ozkan Isik","doi":"10.1155/ijcp/9157147","DOIUrl":"https://doi.org/10.1155/ijcp/9157147","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Aquatic training is emerging as a multifaceted therapy for enhancing health parameters, particularly among elderly populations. This study aimed to investigate the effects of a three-month aquatic training on physical functioning, including balance, muscular strength, and flexibility, among healthy older men.</p>\u0000 <p><b>Methods:</b> From an initial sample of 80 elderly men, 45 healthy participants (mean age: 75.5 years) were randomly assigned to either the intervention (<i>n</i> = 23) or control group (<i>n</i> = 22). The intervention group participated in three 60-min sessions per week for 12 weeks. Functional fitness variables, encompassing upper and lower body flexibility and muscular strength, along with dynamic and static balance, were assessed using multiple tests at both baseline and postintervention. The training load increased gradually over the 12-week program, ranging between 50% and 70% of heart rate reserve (HRR). Exercise intensity was controlled using the rate of perceived exertion (RPE) scale, aiming for a targeted range of 12–15 on the Borg scale. The control group maintained their usual daily activities throughout the study period, providing a basis for comparison with the exercise intervention group.</p>\u0000 <p><b>Results:</b> No significant baseline differences in demographic characteristics were observed between the study groups (<i>p</i> > 0.05). Compared to the control group, the intervention group demonstrated significant improvements across all outcome measures, including static balance, dynamic balance, upper and lower body flexibility, and upper and lower body muscular strength (<i>p</i> < 0.001).</p>\u0000 <p><b>Conclusion:</b> The study findings highlight the efficacy of aquatic training in enhancing various aspects of physical functioning among older men, supporting the growing recognition of aquatic training as an effective therapeutic approach for promoting vitality and independence in elderly populations.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9157147","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Knowledge, Attitudes, and Practices Toward Orthostatic Intolerance Among Surgical Medical Staff in Chongqing, China: A Web-Based Cross-Sectional Study","authors":"Hongjie Yi, Wenfeng Tang","doi":"10.1155/ijcp/6622089","DOIUrl":"https://doi.org/10.1155/ijcp/6622089","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To explore the knowledge, attitudes, and practices (KAPs) toward orthostatic intolerance (OI) among surgical medical staff in Chongqing, China.</p>\u0000 <p><b>Methods:</b> Surgical medical staff of the First Affiliated Hospital of Chongqing Medical University were recruited in this cross-sectional study between March and April 2023. The data were collected using a self-administered questionnaire. Statistical analyses, including tests of relationships such as Spearman correlation analysis and structural equation modeling (SEM), were performed using SPSS 22 and AMOS software.</p>\u0000 <p><b>Results:</b> A total of 392 valid questionnaires were analyzed, including 24 (6.12%) filled out by doctors and 368 (93.88%) filled out by nurses. Among the participants, there were 345 females (88.01%) and 47 males (11.99%), mostly aged between 20 and 40 years (86.7%). The average KAPs scores were 10.02 ± 2.08, 40.48 ± 6.87, and 43.27 ± 8.67, respectively. Positive correlations were found between knowledge and attitudes (<i>r</i> = 0.0289, <i>p</i> < 0.001), knowledge and practices (<i>r</i> = 0.028, <i>p</i> < 0.001), and attitudes and practices (<i>r</i> = 0.594, <i>p</i> < 0.001). SEM revealed direct effects of knowledge on attitudes (Estimate = 0.625, <i>p</i> < 0.001) and attitudes on practices (Estimate = 0.700, <i>p</i> < 0.001), suggesting an indirect effect of knowledge on practices, with knowledge also directly influencing practices (Estimate = 0.375, <i>p</i> = 0.033).</p>\u0000 <p><b>Conclusion:</b> Surgical medical staff in Chongqing demonstrated moderate knowledge, positive attitudes, and moderate practices regarding OI. Targeted interventions to enhance knowledge and attitudes may improve practices and optimize patient outcomes.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/6622089","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143857065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Clinical Characteristics and Drug Susceptibility Profiling of Multidrug-Resistant Pseudomonas aeruginosa Infections","authors":"Mingxia Cai, Zhibin Zhou, Jiaming Huang, Yuxia Du","doi":"10.1155/ijcp/2755014","DOIUrl":"https://doi.org/10.1155/ijcp/2755014","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To investigate the epidemiology of <i>Pseudomonas aeruginosa</i> (PA) in hospitalized patients with PA respiratory infections and to analyze the clinical characteristics and antibiotic resistance profiles of drug-resistant PA, providing valuable insights to inform clinical management strategies.</p>\u0000 <p><b>Methods:</b> A retrospective analysis of clinical data from hospitalized patients with PA respiratory infections was collected and analyzed to investigate the clinical features and their correlation with PA drug resistance.</p>\u0000 <p><b>Results:</b> In the study cohort, 34.1% (<i>n</i> = 93) of patients were classified as having multidrug-resistant <i>Pseudomonas aeruginosa</i> (MDR-PA), while 65.9% (<i>n</i> = 180) were non-MDR-PA. Logistic regression identified that male gender, ICU admission, hemiplegia, and mechanical ventilation were independent risk factors for MDR-PA infection (all <i>p</i> < 0.05). Multivariate analysis showed male gender (OR 2.44, 95% CI 1.15–5.17) and hemiplegia (OR 2.99, 95% CI 1.02–8.82) as significant factors for MDR-PA infection. Both analyses also confirmed mechanical ventilation as an independent risk factor for difficult-to-treat <i>Pseudomonas aeruginosa</i> (DTR-PA) infections. MDR-PA exhibited low susceptibility to meropenem (32.3%) and imipenem (18.3%), whereas aminoglycosides showed higher effectiveness, with over 80% susceptibility against MDR-PA and more than 50% susceptibility against DTR-PA.</p>\u0000 <p><b>Conclusion:</b> Male patients with hemiplegia should be closely monitored for MDR-PA infections when PA is detected. Mechanical ventilation necessitates vigilance against DTR-PA. Aminoglycoside-based combination therapy offers an effective empirical option for resistant PA infections. These findings indicate the need for antimicrobial stewardship or infection control measures to address MDR-PA and DTR-PA infections.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/2755014","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Narrative Review on Predictive Models for Bleeding Risk Associated With Anticoagulant Therapy in Venous Thromboembolism","authors":"Zuoyi Yao, Jichun Zhao","doi":"10.1155/ijcp/4109309","DOIUrl":"https://doi.org/10.1155/ijcp/4109309","url":null,"abstract":"<div>\u0000 <p>The prediction of bleeding risk is crucial for the standardized treatment of venous thromboembolism. This article introduces the definition and importance of predicting anticoagulant therapy–related bleeding in venous thromboembolism and reviews the latest research on existing anticoagulant therapy-related bleeding risk prediction models, especially HAS-BLED, RIETE, and VTE-BLEED models in recent years. It is found that existing clinical factor–based bleeding risk prediction models have certain predictive significance for bleeding events, but there is still a gap compared to ideal models, and dynamic evaluation is more important. This review also explores new models for predicting bleeding risk and provides a reference for clinical physicians to develop anticoagulant strategies.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/4109309","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143852710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Determinants of Adverse Newborn Outcome Among Adolescent Pregnancy in Nigist Elleni Mohammed Memorial Referral Hospital, Central Ethiopia: A Case-Control Study","authors":"Lonsako Abute Woiloro, Amene Abebe Kerbo, Kasa Daka Gidebo, Bizuayehu Belete Erdedo, Belay Erchafo Lubego, Dawit Sulamo Erjino, Rediet Dessalegne Dayemo, Mengistu Meskele Koyra","doi":"10.1155/ijcp/5825053","DOIUrl":"https://doi.org/10.1155/ijcp/5825053","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Adolescent pregnancy remains a common healthcare problem in low- and middle-income countries, and it is associated with higher maternal and neonatal complications. Adverse neonatal outcomes among adolescents are one of the most common causes of maternal and neonatal mortality and morbidity. This study was carried out to evaluate the adverse neonatal outcomes associated with teenage pregnancy in Nigist Elleni Mohammed Memorial Referral Hospital, Central Ethiopia.</p>\u0000 <p><b>Methods:</b> This case-control study was carried out on 75 cases and 150 matched control adolescent pregnant women between June and November, 2021. A structured questionnaire that has been validated and considered credible was employed as a data collection technique. Consecutive sampling technique was used to select study participants. Descriptive statistics and logistic regression analysis were used to look at the relationship between the independent and dependent variables. A <i>p</i> value of less than 0.05 was used to declare significant threshold.</p>\u0000 <p><b>Result:</b> There were 150 controls and 75 patients in this study, with a 100% response rate. From the participants, 84% of cases and 76.7% of controls were in the age group of 15–19 years old. Out of the 75 cases, 38.3% had low birth weight children, 32.8% had preterm delivery, and 28.7% had poor Apgar scores. From the participants, 64.5% of the controls and 56% of the cases have good knowledge about the risks associated with low birth outcomes. Adverse newborn outcomes were independently predicted by mothers living in rural areas 3.04 (1.46–7.66), those with gestational diabetes 4.26 (2.65–2.34), and mothers experiencing any complication during pregnancy 4.02 (1.13–7.75).</p>\u0000 <p><b>Conclusion:</b> Adolescent pregnancies in rural areas, as well as those with complications and gestational diabetes, were the study’s predictive variables. In order to reduce the chance of an adverse newborn outcome, adolescent pregnant women living in rural areas and those who have gestational diabetes should be made aware of the dangers associated with their age and encouraged to consult with health professionals on a regular basis.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5825053","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143840903","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kun Yung Kim, Young-Min Han, Myoung-Hwan Ko, Jeong-Hwan Seo, Sung-Hee Park, Yu Hui Won, Gi-Wook Kim
{"title":"Effects of Transcatheter Arterial Embolization for Chronic Intractable Shoulder Pain: A Prospective Clinical Study","authors":"Kun Yung Kim, Young-Min Han, Myoung-Hwan Ko, Jeong-Hwan Seo, Sung-Hee Park, Yu Hui Won, Gi-Wook Kim","doi":"10.1155/ijcp/9964536","DOIUrl":"https://doi.org/10.1155/ijcp/9964536","url":null,"abstract":"<div>\u0000 <p><b>Objectives:</b> Based on the idea that the neovessels and nerves are a possible cause of pain, transcatheter arterial embolization (TAE) has been reported as a novel adjunctive treatment with good outcomes. Purpose of this was to examine the short-term outcomes of TAE including 1-day follow-up results in patients with chronic shoulder pain using patient-reported outcome measures.</p>\u0000 <p><b>Study Design:</b> Prospective study.</p>\u0000 <p><b>Methods:</b> TAE was performed with a suspension of imipenem/cilastatin sodium in contrast agent. Subjects were assessed before, 1 day after, and 1 month after the procedure using the visual analogue scale (VAS, 0–10), shoulder pain and disability index (SPADI, 0–100), and Constant–Murley score (CMS, 0–100).</p>\u0000 <p><b>Results:</b> A total of 10 patients were enrolled. All procedures were technically successful with the radial artery approach. Abnormal neovessels with angiographic blushes were identified in all cases, with a mean of 3.3 abnormal neovessels per patient (range, 2–4) and a total of 41 arteries embolized, averaging 4.1 vessels per patient (range, 3–5). Baseline VAS, SPADI, and CMS were 3.5, 50.0, and 47.4, respectively. The 1-day follow-up (VAS, 2.0; SPADI, 26.3; CMS, 68.1; <i>p</i> ≤ 0.001 compared to baseline) and 1-month follow-up (VAS, 1.7; SPADI, 24.3; CMS, 72.8; <i>p</i> ≤ 0.002 compared to baseline) demonstrated significant improvements. The 1-day and 1-month follow-up results were not significantly different.</p>\u0000 <p><b>Conclusions:</b> Substantial pain relief and functional scales improvement were observed both immediately and 1 month after TAE in chronic intractable shoulder pain. TAE may be an effective alternative treatment for patients with shoulder pain who do not respond to conservative or surgical treatment.</p>\u0000 <p><b>Trial Registration:</b> Korean Registry of Clinical Trials: KCT0004720</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9964536","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143836123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abdulaziz Alrubayyi, Reza Fahimi, Muntaha Hassan, Jason Madan, Olalekan A. Uthman
{"title":"Current Clinical Practices and Future Perspectives for Primary Healthcare Use of Point-of-Care Devices: A Scoping Review","authors":"Abdulaziz Alrubayyi, Reza Fahimi, Muntaha Hassan, Jason Madan, Olalekan A. Uthman","doi":"10.1155/ijcp/4742851","DOIUrl":"https://doi.org/10.1155/ijcp/4742851","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Expanding access to screening through primary care is essential to address changes in disease patterns, patients’ needs, and demographics. Point-of-care test (POCT) devices play a crucial role in providing primary care and have positive operational and economic impacts compared to central laboratories. Despite their importance, the implementation of POCT devices in primary care remains low. This scoping review aims to map the current evidence on POCT types and their current uses in primary care.</p>\u0000 <p><b>Methods:</b> A scoping review was conducted using the framework proposed by Arksey and O’Malley, and further refined by Levac et al. and the Joanna Briggs Institute. Our process included five stages: identifying the research question, identifying relevant studies, study selection, charting the data, and collating, summarizing, and reporting the results. We searched MEDLINE (Ovid), CINAHL, Embase, Web of Science, Cochrane Library, and Google Scholar for studies published between 2018 and 2023 on the use of POCTs in primary care settings for adult populations. Our findings were summarized using descriptive statistics and thematic analysis.</p>\u0000 <p><b>Results:</b> The search yielded 43,913 publications, of which, 167 met the inclusion criteria. From these studies, biomarker detection tests were used in 33.5%, antibody tests in 21.6%, other POCTs in 17.4%, POC technologies in 11.4%, antigen tests in 8.4%, and POC molecular tests in 7.8%. Across studies, 46.7% targeted communicable diseases, 39.5% targeted noncommunicable diseases, and 13.8% for other diseases. POC devices are mainly used for communicable diseases in urban healthcare settings, particularly in low- and middle-income countries (LMIC). POC devices are used primarily for noncommunicable diseases in urban healthcare settings, particularly in high-income countries.</p>\u0000 <p><b>Conclusion:</b> This scoping review has mapped the evidence and highlighted gaps regarding POCTs used in primary care. The findings can be used to design and effectively implement sustainable patients’ healthcare journeys to accommodate the changes in patients’ demographics and healthcare needs.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/4742851","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143826699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}