International Journal of Clinical Practice最新文献

{"title":"Life’s Essential 8 and Mortality Risk in Cardiovascular Disease: Results From a Nationwide Population Survey","authors":"Yang Zhang,&nbsp;Zhiwei Xu,&nbsp;Lin Li,&nbsp;Xiaoya Hong,&nbsp;Hui Xia","doi":"10.1155/ijcp/6659458","DOIUrl":"https://doi.org/10.1155/ijcp/6659458","url":null,"abstract":"<p>Life’s Essential 8 (LE8), a comprehensive metric integrating behavioral and physiological cardiovascular health factors, may serve as a valuable stratification tool for identifying high-risk subgroups within patients already diagnosed with cardiovascular disease (CVD). In this study, we analyzed data from 3681 individuals with CVD from the US National Health and Nutrition Examination Survey (2007–2018) linked with mortality data. LE8 scores were calculated based on multidomain health indicators, and survival outcomes were assessed across score quartiles. We employed adjusted weighted Cox regression analyses, which accounted for the complex survey design by incorporating appropriate sample weights, strata, and primary sampling units through survey-weighted statistical methods. Higher LE8 scores were significantly associated with reduced all-cause mortality (adjusted HR per unit increase: 0.76 and 95% CI: 0.69–0.85), with a 60% reduction in mortality risk observed in the highest quartile compared with the lowest. These associations remained robust after adjustment for key sociodemographic covariates. Restricted cubic spline analysis confirmed a dose-response relationship between LE8 and mortality risk. Our findings underscore the value of composite health metrics such as LE8 in refining disease taxonomies, enhancing risk stratification, and potentially guiding personalized intervention strategies. This population-scale phenotypic analysis offers a clinical foundation for future AI-driven or multiomics investigations to unravel the mechanistic underpinnings and identify modifiable therapeutic targets among phenotypically diverse CVD populations.</p>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/6659458","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitude, and Practice of Anesthesiologists Regarding Perioperative Neurocognitive Dysfunction: A Cross-Sectional Study","authors":"Rui Zhou,&nbsp;Yumeng Fu,&nbsp;Xinmin Yan,&nbsp;Baoli Cheng","doi":"10.1155/ijcp/7302873","DOIUrl":"https://doi.org/10.1155/ijcp/7302873","url":null,"abstract":"<p>This study assessed anesthesiologists’ knowledge, attitude, and practice (KAP) regarding perioperative neurocognitive dysfunction (PND). This multicenter, cross-sectional study was conducted among anesthesiologists in mainland China from February 23, 2024, to March 23, 2024. Self-administered questionnaires were used to collect demographic information and assess KAP scores. Finally, 594 nonproblematic questionnaires were included. Among the respondents, 311 (52.36%) were male, and 172 (28.96%) had received training related to PND. The mean scores for the KAP dimensions were 8.98 ± 2.32 (range: 0–13), 35.53 ± 3.00 (range: 8–40), and 28.49 ± 6.70 (range: 8–40), respectively. According to multivariable logistic regression analysis, higher knowledge scores (odds ratio [OR] = 1.099, 95% confidence interval [CI]: 1.012–1.194, <i>p</i> = 0.025), higher attitude scores (OR = 1.112, 95% CI: 1.043–1.188, <i>p</i> = 0.001), and participation in PND-related training (OR = 2.876, 95% CI: 1.973–4.207, <i>p</i> &lt; 0.001) were associated with proactive practice. Path analysis revealed that knowledge was associated with attitude (<i>β</i> = 0.31, <i>p</i> &lt; 0.001) and practice (<i>β</i> = 0.52, <i>p</i> &lt; 0.001) and that attitude was associated with practice (<i>β</i> = 0.29, <i>p</i> = 0.002). Anesthesiologists in mainland China demonstrate limited knowledge but a positive attitude and a proactive approach to PND. Targeted educational interventions are recommended to improve anesthesiologists’ understanding and management of PND, enhancing perioperative care and patient outcomes.</p>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7302873","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative Urine Culture Combined With Stone Diameter Are Often Indicators of the Stone Culture Results","authors":"Dekai Hu,&nbsp;Defeng Ge,&nbsp;Jiashan Pan,&nbsp;Junzhi Zhang,&nbsp;Xiaowei Wang,&nbsp;Yang Chen,&nbsp;Zongyao Hao","doi":"10.1155/ijcp/6848449","DOIUrl":"https://doi.org/10.1155/ijcp/6848449","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Purpose</h3>\u0000 \u0000 <p>The current clinical guidelines recommend routine stone bacterial culture for patients who have undergone stone surgery. However, the results of bacterial culture are obtained after several days, which delay the implementation of early treatment postsurgery. In this study, we performed stone bacterial culture for several surgical patients and predicted the results and types of stone bacterial culture based on specific parameters on admission. This case provides important clinical data that will guide the implementation of early detection and management of postoperative infections.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Patients who underwent stone surgery between October 2023 and January 2024, all of whom underwent urine and stone bacterial culture were enrolled in the study. Their results were processed and compared using logistic regression analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 165 patients were enrolled in the study, among whom 57 had positive stone cultures, 37 had positive urine culture (UC), and 21 had both positive stone and urine cultures. Univariate analysis indicated that the positive stone cultures were associated with preoperative UC and preoperative use of antibiotics. Multivariate logistic regression analysis further confirmed that positive preoperative UC was a significant risk factor for stone culture (SC). Patients with consistent results in both UC and SC exhibited larger kidney stone diameters. Furthermore, the combination of UC and stone diameter could effectively predict the bacterial species of SC (AUC = 0.817).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>In patients with large-diameter kidney stones, the bacteria identified in UC were often similar to those detected in the SC.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/6848449","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Motor System Reorganization After Pediatric Hemispherectomy: Mechanisms, Predictors, Imaging, and Neurorehabilitation Implications","authors":"Yilin Zhao","doi":"10.1155/ijcp/4807957","DOIUrl":"https://doi.org/10.1155/ijcp/4807957","url":null,"abstract":"<p>Hemispherectomy (HS) is recognized as a highly effective surgical intervention for pediatric patients with refractory epilepsy. After surgery, seizures are not only effectively controlled, but improvements in gross and fine motor functions of the contralateral limbs are also observed in some patients. This phenomenon underscores the remarkable neural plasticity, whereby the contralateral hemisphere demonstrates functional reorganization and advancement postoperatively. The present literature review synthesizes prior studies on motor function recovery after HS in patients with refractory epilepsy, elucidating the mechanisms by which postoperative motor functions are sustained by the contralateral hemisphere. Key factors influencing postoperative motor outcomes are highlighted, including age at surgery and underlying etiology, with particular emphasis on the critical role of white matter tracts originating from the ipsilateral cortex in facilitating motor compensation after surgery. This review seeks to advance comprehension of the inherent mechanisms underlying neural plasticity in the human cerebral hemispheres, offering valuable insights into the reorganization of the postoperative motor system.</p>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/4807957","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Female Sex, Lower Waist Circumference, Statin, and Calcium Channel Blocker Use Are Associated With Reduced Odds of Uncontrolled Hypertension: A Population-Based Study","authors":"Sara Shojaei-Zarghani,&nbsp;Shahrokh Sadeghi Boogar,&nbsp;Leila Mansourabadi,&nbsp;Mohammad Reza Fattahi,&nbsp;Ali Reza Safarpour","doi":"10.1155/ijcp/5549780","DOIUrl":"https://doi.org/10.1155/ijcp/5549780","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>The lack of control of hypertension increases the risk of heart disease, kidney disease, and stroke. This study aimed to assess the prevalence of uncontrolled hypertension and its associated risk factors among the registered population of the Prospective Epidemiological Research Studies in IrAN (PERSIAN) Kavar cohort study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The analysis included patients with diagnosed hypertension who were taking antihypertensive drugs during the baseline phase of the Kavar cohort study. Uncontrolled hypertension was defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Among the 755 patients included in the study (36% male), 275 subjects (36.4%, 95% confidence interval [CI]: 33.0–40.0) had uncontrolled hypertension. Multivariable regression analysis showed that female sex (odds ratio [OR] = 0.43, 95% CI: 0.31–0.60, <i>p</i> value &lt; 0.001), statin use (OR = 0.69, 95% CI: 0.50–0.96, <i>p</i> value = 0.025), and calcium channel blocker (CCB) intake (OR = 0.66, 95% CI: 0.47–0.92, <i>p</i> value = 0.013) were associated with decreased odds of uncontrolled hypertension. In addition, a waist circumference elevation was found to be significantly associated with uncontrolled hypertension (OR = 1.05, 95% CI: 1.01–1.08, <i>p</i> value = 0.004).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Despite receiving antihypertensive therapy, approximately 36% of the study population had uncontrolled hypertension. Female patients and those taking statins and CCBs had a reduced likelihood of experiencing uncontrolled hypertension, while an increased waist circumference was associated with higher odds of uncontrolled hypertension.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5549780","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cross-Cultural Adaptation and Validation of the Danish Version of the Avoidance–Endurance Questionnaire (AEQ): A Dual-Panel Approach","authors":"Lotte Ladegaard Kristensen,&nbsp;Thorvaldur Skúli Pálsson,&nbsp;Pablo Bellosta-López","doi":"10.1155/ijcp/2901600","DOIUrl":"https://doi.org/10.1155/ijcp/2901600","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>To translate and culturally adapt the Avoidance–Endurance Questionnaire (AEQ) into Danish, assessing both fear avoidance responses (FARs) and endurance responses (ERs), while investigating relevant psychometric properties.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Panel 1 translated AEQ using the dual-panel method. Panel 2 evaluated the translation and face validity assessed by interviewing both panels. The questionnaire was administered to 119 chronic pain patients, and their responses were used to assess factor structure and internal consistency. Of these, 90 of the participants completed the questionnaire again, and their responses were used to evaluate test–retest reliability.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Both patients and clinicians assessed DK-AEQ with good face validity. Confirmatory factor analysis showed adequate to good fit for affective and cognitive subscales, while adequate to poor fit for behavioral subscales. The internal consistency was adequate in subscales of FAR (Cronbach´s <i>α</i> = 0.8–0.9) and ER (Cronbach’s <i>α</i> = 0.7–0.9). An excellent test–retest reliability was found for FAR 0.94 (95%, CI: 0.91–0.96) and ER 0.92 (95%, CI: 0.88–0.95).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>The Danish version of the AEQ is a valid and reliable tool for assessing FAR and ER in people with chronic pain. It provides clinicians with valuable information on the affective, cognitive, and behavioral mechanisms underlying pain behavior, which can support therapeutic dialog. Potentially, implementing the DK-AEQ may enable stratification of management strategies for individuals living with chronic pain in Denmark.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/2901600","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145223759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Understanding Risk Factors and Population Attributable Fractions for Ever-Terminated Pregnancy in Bangladesh: Insights From Bangladesh Demographic and Health Survey Data (2014–2022)","authors":"Sumaya Sultana,&nbsp;Khondokar Naymul Islam,&nbsp;Benojir Ahammed","doi":"10.1155/ijcp/8867628","DOIUrl":"https://doi.org/10.1155/ijcp/8867628","url":null,"abstract":"<div>\u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Pregnancy termination (PT) poses significant public health challenges for women in low- and middle-income countries such as Bangladesh, yet understanding its trends and risk factors remains limited. This study aims to address this gap by analyzing the associated risk factors and population attributable fractions (PAFs) for PT in Bangladesh.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This study analyzed data from Bangladesh Demographic and Health Surveys (2014–2022) using consistent methodologies among women of reproductive age. Logistic regression models and PAF were used to assess the risk factors for PT and quantify their contributions, using a 5% level of significance.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 46,410 records were analyzed in this study, comprising 17,071 from 2014, 19,508 from 2017 to 18, and 9831 from 2022. The overall prevalence of PT was 20.62%. Year-specific rates were 19.21% in 2014, 20.21% in 2017-18, and 23.86% in 2022. Across all years, significant risk factors for PT included a maternal age of ≥ 20 years (AOR = 2.70, 95% CI: 2.39–3.04), being employed (AOR = 1.18, 95% CI:1.12–1.23), and overweight/obese (AOR = 1.20, 95% CI: 1.14–1.26), having ≥ 2 children (AOR = 1.32, 95% CI: 1.24–1.40), residing in urban areas (AOR = 1.09, 95% CI: 1.04–1.15), and first sex before 18 years of age (AOR = 1.10, 95% CI: 1.04–1.17), all of which were associated with an increased risk of PT. PAF analysis highlighted maternal age (≥ 20 years) as the most influential factor, accounting for 60.59% of PT risk, followed by ≥ 2 children (18.59%), overweight/obese (8.82%), first sex before 18 years (6.76%), and employment status (6.67%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>This study identifies key risk factors for PT in Bangladesh, including maternal age, working status, obesity, and first sex before 18 years of age. To mitigate these risks, targeted public health interventions, reproductive health education, and improved prenatal care are essential to ensure better maternal health and reducing PT prevalence in Bangladesh.</p>\u0000 </section>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/8867628","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Qidantang Granule Ameliorates Diabetic Kidney Disease in Mice by Inhibiting Cuproptosis","authors":"Tengfei Wu,&nbsp;Yirong Chen,&nbsp;Yilei Cong,&nbsp;Xinyu Yang,&nbsp;Jie Zhang,&nbsp;Qin Liu,&nbsp;Yue Yuan,&nbsp;Hua Yang","doi":"10.1155/ijcp/6675290","DOIUrl":"https://doi.org/10.1155/ijcp/6675290","url":null,"abstract":"<p>Diabetic kidney disease (DKD) is a significant contributor to chronic kidney disease and end-stage renal disease. Cuproptosis, a newly recognized type of copper-dependent cellular demise, has been associated with the pathophysiology of DKD. Qidantang Granule, a traditional Chinese medicinal formulation, has demonstrated the renoprotective benefits, although its function in controlling cuproptosis is ambiguous. A mouse model of DKD was generated using streptozotocin (STZ) in male C57BL/6J mice. Mice received oral administration of Qidantang Granule (200 mg/kg/day) or a vehicle for a duration of 9 weeks. Renal function, histopathology, apoptosis, oxidative stress, and metabolic alterations were evaluated using biochemical tests, ELISA, and histological staining. Western blotting and qRT-PCR identified proteins and genes associated with apoptosis and cuproptosis, whereas inductively coupled plasma mass spectrometry assessed renal copper levels. Qidantang Granule treatment significantly reduced blood glucose levels, improved renal function parameters, and alleviated histological damage in DKD mice. Treatment inhibited Bax and active caspase-3 expression, decreased malondialdehyde levels, restored MnSOD activity and ATP content, and normalized levels of pyruvate, α-ketoglutarate, and succinic acid levels. Qidantang Granule decreased renal copper levels, downregulated SLC31A1 and Hsp70 expression, and reinstated lipoylation of dihydrolipoamide S-acetyltransferase and dihydrolipoamide S-succinyltransferase, signifying the suppression of cuproptosis. Qidantang Granule ameliorates DKD in STZ-induced mice by diminishing oxidative stress, modulating energy metabolism, and inhibiting cuproptosis, underscoring its promise as a treatment approach for DKD.</p>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/6675290","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of One-Year Survival and Quality of Life After Intensive Care: A Retrospective 5-Year Study","authors":"Recep Civan Yüksel,&nbsp;Birkan Ülger,&nbsp;Kamil Deveci,&nbsp;Şahin Temel,&nbsp;Murat Sungur,&nbsp;Kürşat Gündoğan","doi":"10.1155/ijcp/9302538","DOIUrl":"https://doi.org/10.1155/ijcp/9302538","url":null,"abstract":"<p><b>Background/Objective:</b> The post-intensive care unit (ICU) period significantly impacts patients’ overall well-being, raising concerns among patients, families, healthcare professionals, and decision-makers. This study aims to evaluate 1-year survival rates, return to work, and daily functionality of individuals discharged from the ICU.</p><p><b>Materials and Methods:</b> A retrospective analysis was conducted in a medical ICU, focusing on patients with a minimum 48-h ICU stay who were subsequently discharged from the hospital.</p><p><b>Results:</b> The study included 154 patients with a median age of 51 (IQR: 34–68) years, of whom 79 (51%) were male. The 1-year mortality rate was 23.4%. Within the first year, rehospitalization occurred in 54.5%, and ICU readmission was observed in 20.1%. Notably, 89.8% of the patients were able to perform self-care activities, such as toileting and dressing. However, 63.6% of the patients had not returned to work within the first year. A comparison between patients requiring critical interventions and those who did not revealed a return-to-work rate of 21.4% for the former and 50% for the latter (<i>p</i> = 0.002).</p><p><b>Conclusion:</b> The findings indicate that approximately one-quarter of patients treated in intensive care and discharged from the hospital died within 1 year. While a significant proportion (90%) could independently manage self-care tasks, the majority experienced delays in returning to work. These findings highlight the need for enhanced post-ICU care to improve patient outcomes.</p>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9302538","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145224309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Wa-Shi Pulling in Enhancing Core Strength for Sacroiliac Joint Pain Syndrome: Empirical Evidence of Its Effectiveness","authors":"Jianfeng Shu,&nbsp;Jianke Yang,&nbsp;Binghua Fan,&nbsp;Dong Li,&nbsp;Weijing Tao,&nbsp;Shu Chen","doi":"10.1155/ijcp/6538085","DOIUrl":"https://doi.org/10.1155/ijcp/6538085","url":null,"abstract":"<p><b>Introduction:</b> Optimal management of sacroiliac joint pain syndrome necessitates timely and effective therapeutic interventions to achieve favorable clinical outcomes. This study was designed to investigate the efficacy of a combined treatment approach, integrating Wa-shi pulling (WP) with core muscle strengthening exercises (CMSE), in patients with sacroiliac joint pain syndrome.</p><p><b>Methods:</b> A prospective study was conducted on patients diagnosed with sacroiliac joint pain syndrome between October 1, 2019, and June 30, 2022. Participants were carefully selected and randomly allocated into two groups: the WP group and the WP + CMSE group.</p><p><b>Results:</b> A total of 123 patients with sacroiliac joint pain syndrome were enrolled in the study. Following the intervention, significant reductions were observed in both McGill Pain Questionnaire scores and lumbosacral angles compared to baseline values (all <i>p</i> &lt; 0.05). The WP + CMSE group demonstrated more pronounced reductions in McGill Pain Questionnaire scores (<i>p</i> = 0.029) and greater improvements in lumbosacral angles postintervention. Additionally, JOA scores increased significantly for both groups after treatment (all <i>p</i> &lt; 0.05), with the WP + CMSE group exhibiting a more substantial improvement compared to the WP group (<i>p</i> = 0.039). These findings suggest a more robust therapeutic effect in the combined treatment group.</p><p><b>Conclusion:</b> The integration of WP and CMSE showed therapeutic effects in sacroiliac joint pain syndrome, though with variability in statistical robustness across outcomes after Bonferroni correction. Evidence for a synergistic effect remains strongest for pain relief, with conclusions regarding lumbosacral biomechanics and functional status requiring cautious interpretation pending further validation. This study provides preliminary support for the therapeutic potential of combining these modalities, with the pain-specific findings meriting consideration in clinical practice.</p><p><b>Trial Registration:</b> Chinese Registry of Clinical Trials: MR-33-20-001928</p>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/6538085","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145146847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}