Muteb Algharbi, Hatem D. Alshammari, Nashwa Alzaki Ali Bushara, Abdulrahman K. Alshammari, Mohammed K. Alotaibi, Njoud Abuhaimed, Faris O. Alotaibi, Heba F. Alsubhi, Haitham A. Alraddadi, Mohammad H. Aljoudi, Mohammed A. Alqarni, Ebtsam Aledaili, Ammar A. Siddiqui
{"title":"Evaluating Self-Perceived Oral Health Status and Sociodemographic Factors in Saudi Arabian Children: An Observational Study","authors":"Muteb Algharbi, Hatem D. Alshammari, Nashwa Alzaki Ali Bushara, Abdulrahman K. Alshammari, Mohammed K. Alotaibi, Njoud Abuhaimed, Faris O. Alotaibi, Heba F. Alsubhi, Haitham A. Alraddadi, Mohammad H. Aljoudi, Mohammed A. Alqarni, Ebtsam Aledaili, Ammar A. Siddiqui","doi":"10.1155/ijcp/1776660","DOIUrl":"https://doi.org/10.1155/ijcp/1776660","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> It is critical to measure children’s opinions of their oral health to understand their attitudes and self-awareness, spot discrepancies between their perceived and actual health, and develop tailored intervention strategies. In addition, it supports understanding the impact on parenting styles and the general quality of life of the children, resulting in more specialized and effective dental health initiatives.</p>\u0000 <p><b>Objectives:</b> The present study was planned to evaluate children’s self-perceptions towards their oral health status across Saudi Arabia.</p>\u0000 <p><b>Methods:</b> Data for this observational study were obtained from children by licensed dentists working in various regions of the country using a nonprobability sampling technique. Inferential and descriptive statistics were used to present data. The World Health Organization (WHO) basic survey method questionnaire was used as a study tool.</p>\u0000 <p><b>Results:</b> The present study recruited <i>N</i> = 606 participants by the convenient sampling technique. Almost half (50%) of the participants believed their oral health status to be varied from good to excellent. For certain regions such as Medina and Riyadh, the dominant category of self-perception was “Excellent,” whilst for Ha’il region, it was found to be “average,” followed by “poor” in Makkah. Self-perceptions toward the oral health status were found to be associated with various sociodemographic factors, such as parents’ education, age of children, gender, and region. Self-perception of oral health was significantly associated with parental education, age, gender, and regional differences.</p>\u0000 <p><b>Conclusion:</b> Most participants believed their oral health status to be either good or average. The responses varied among regions. The oral health status was found to be associated with sociodemographic variables. Future research should further investigate the factors contributing to regional differences and evaluate targeted interventions. The findings emphasize the importance of tailoring interventions to specific regions, as variations in self-perceptions of oral health may indicate underlying disparities in health awareness and access to care among children in Saudi Arabia.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/1776660","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Qutaiba Ababneh, Rahaf Alqazaq, Ziad Jaradat, Hala Khanjar
{"title":"Interspecies Competitive Interactions of Clinical Isolates of Acinetobacter baumannii With Klebsiella pneumoniae, Staphylococcus aureus, and Pseudomonas aeruginosa","authors":"Qutaiba Ababneh, Rahaf Alqazaq, Ziad Jaradat, Hala Khanjar","doi":"10.1155/ijcp/5516061","DOIUrl":"https://doi.org/10.1155/ijcp/5516061","url":null,"abstract":"<div>\u0000 <p>Many microbial infections are caused by multiple species. However, little is known about the detailed interactions and mechanisms underlying competition between coexisting pathogens. <i>Acinetobacter baumannii</i> is a major nosocomial pathogen that is often involved in mixed infections. To date, few studies have focused on the interactions between <i>A</i>. <i>baumannii</i> and other common coinfectious microbes. In this study, we aimed to investigate the interspecies competition among clinical <i>A. baumannii</i> isolates with <i>Klebsiella pneumoniae</i>, <i>Staphylococcus aureus</i>, <i>and Pseudomonas aeruginosa</i>. <i>A. baumannii</i> isolates were recovered from 56 patients in three major hospitals in Jordan between 2018 and 2019. The isolates were obtained from various clinical specimens, including sputum, wound, blood, and urine. Clinical isolates of methicillin-resistant <i>S</i>. <i>aureus</i>, <i>P</i>. <i>aeruginosa</i>, <i>and K</i>. <i>pneumoniae</i> were also used. Interactions between <i>A</i>. <i>baumannii</i> isolates and each of the other species were investigated through 168 interspecies competition assays, and each experiment was done in duplicate. The results revealed that <i>A</i>. <i>baumannii</i> outcompeted <i>K</i>. <i>pneumoniae</i>, significantly reducing its growth, with the degree of reduction varying depending on the clinical origin of <i>the A</i>. <i>baumannii</i> isolates. Moreover, the growth of <i>S</i>. <i>aureus</i> was decreased regardless of the <i>A</i>. <i>baumannii</i> clinical origin, with a higher reduction compared to <i>K</i>. <i>pneumoniae</i>. On the other hand, the presence of <i>P</i>. <i>aeruginosa</i> led to a significant decrease in the <i>A</i>. <i>baumannii</i> growth, while the growth of <i>P</i>. <i>aeruginosa</i> was significantly increased after coculture with <i>A. baumannii</i>. The present study provides evidence that the <i>A</i>. <i>baumannii</i> isolates have competitive advantages over both <i>S</i>. <i>aureus</i> and <i>K</i>. <i>pneumoniae</i>. In contrast, <i>P</i>. <i>aeruginosa</i> outcompetes <i>A</i>. <i>baumannii</i> isolates. Our findings provide new insights to identify potential therapeutics to control coinfections.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5516061","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143762024","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Assessing Knowledge and Attitude of Pediatricians and Pharmacists Regarding Monitoring Unbound Valproic Acid Concentration in Pediatric Patients With Hypoalbuminemia","authors":"Nada Safhi, Mayam Alharthi, Hanadi Alrammaal, Rahaf Ali, Naji Alsulami","doi":"10.1155/ijcp/5591970","DOIUrl":"https://doi.org/10.1155/ijcp/5591970","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Valproic acid (VPA), an antiepileptic medication, is widely used in pediatric settings. Around 90%–95% of VPA is bound to plasma proteins, predominately albumin. Physiological alterations leading to hypoalbuminemia may increase free VPA concentrations. In such a case, a total VPA may reflect therapeutical total concentration, while the free VPA concentration could be supratherapeutic. Monitoring of total VPA concentrations solely in hypoalbuminemia patients may mislead clinical decisions. The aim of this study is to assess the awareness, knowledge, and attitude levels of pediatric’ physicians and pharmacists regarding monitoring of unbound VPA concentrations in pediatric patients with hypoalbuminemia.</p>\u0000 <p><b>Method:</b> A cross-sectional study was conducted from September to October 2023 in multicenter in Makkah, Saudi Arabia. Sociodemographic information of registered pediatric clinicians and pharmacists were collected. Participants’ knowledge and practice regarding monitoring of VPA were assessed via a reviewed questionnaire.</p>\u0000 <p><b>Result:</b> A total of 226 participants completed the survey. Around 62% of respondents (<i>n</i> = 141) stated knowing how to monitor VPA levels, but only 19.9% (<i>n</i> = 45) were aware of the association between VPA and albumin plasma concentrations. About half of participants reported availability of total VPA assay in their institutions (<i>n</i> = 121, 53%), while minor percentage reported the availability of measuring free VPA concentrations in their institutions (<i>n</i> = 24, 10.6%). Over half of participants do not check albumin levels while monitoring VPA (<i>n</i> = 132, 58.4%). A statistically significant associations between VPA positive knowledge score were noted with age (<i>p</i> = 0.019), gender (<i>p</i> = 0.009), healthcare specialty (<i>p</i> < 0.001), and years of experience (<i>p</i> = 0.001). None of these factors were significantly associated with positive practice toward VPA monitoring.</p>\u0000 <p><b>Conclusion:</b> The suboptimal practice of monitoring free VPA concentrations in cases of hypoalbuminemia in pediatric settings, mainly due to lack of awareness. Healthcare providers should be educated regarding the importance of monitoring free VPA concentration in the case of hypoalbuminemia.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5591970","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749599","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Probiotics′ Effects on Depression, High-Sensitivity C-Reactive Protein (hs-CRP), and Oxidative Stress in Patients With Multiple Sclerosis: A Meta-Analysis","authors":"Seyed-Amir Tabatabaeizadeh, Niayesh Tafazoli","doi":"10.1155/ijcp/3754973","DOIUrl":"https://doi.org/10.1155/ijcp/3754973","url":null,"abstract":"<div>\u0000 <p><b>Objectives:</b> Major depressive disorder (MDD) is highly prevalent in patients with multiple sclerosis (MS). There is evidence that the gut microbiota affect the inflammatory responses and oxidative status in MS and may affect depression signs and symptoms in these patients. Based on this fact, this updated meta-analysis assessed the effect of probiotic supplementation on the Beck Depression Inventory (BDI), high-sensitivity C-reactive protein (hs-CRP), total antioxidant capacity (TAC), and malondialdehyde (MDA) in patients with MS.</p>\u0000 <p><b>Methods:</b> A systematic literature search was done for English literature through PubMed/Medline, Cochrane Library, Google Scholar, and ScienceDirect from 1 January 2011 to 1 June 2024. This study followed the PRISMA guidelines. Based on the heterogeneity, the random-effects or fixed-effects models were used in the present meta-analysis.</p>\u0000 <p><b>Results:</b> After checking for eligibility, four RCTs were included in the final analysis. There was an improvement in BDI-II score, hs-CRP level, MDA, and TAC in patients with MS (BDI-II score: MD = −2.78; 95% CI, −3.32 to −2.24; <i>Z</i> = 10.09; <i>p</i> < 0.00001; <i>I</i><sup>2</sup> = 57%; <i>p</i> = 0.1; hs-CRP level: MD = −1.69; 95% CI, −1.98 to −1.40; <i>Z</i> = 11.38; <i>p</i> < 0.00001; <i>I</i><sup>2</sup> = 0%; <i>p</i> = 0.96; MDA: MD = −0.37; 95% CI, −0.52 to −0.23; <i>Z</i> = 5.00; <i>p</i> < 0.00001; <i>I</i><sup>2</sup> = 90%; <i>p</i> < 0.0001; and TAC: MD = 5.48; 95% CI, −6.71 to 17.66; <i>Z</i> = 0.88; <i>p</i> = 0.38; <i>I</i><sup>2</sup> = 93%; <i>p</i> < 0.00001).</p>\u0000 <p><b>Conclusion:</b> This meta-analysis suggests that probiotic supplementation has improved BDI scores and inflammatory and oxidative status. This finding promises that probiotic supplementation can be considered as a therapeutic option for depression symptoms and inflammatory status in patients with MS. However, more interventional studies are required to assess the complex relationship between MS, depression, and the gut microbiome. PROSPERO Registration ID: CRD42024552648.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/3754973","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sandra León-Herrera, Mario Samper-Pardo, Bárbara Oliván-Blázquez, Rosa Magallón-Botaya, Verónica Casado-Vicente, Raquel Sánchez-Recio, Rafael Sánchez-Arizcuren
{"title":"Effectiveness of ReCOVery APP to Improve the Quality of Life of Long COVID Patients: A 6-Month Follow-Up Randomized Clinical Trial","authors":"Sandra León-Herrera, Mario Samper-Pardo, Bárbara Oliván-Blázquez, Rosa Magallón-Botaya, Verónica Casado-Vicente, Raquel Sánchez-Recio, Rafael Sánchez-Arizcuren","doi":"10.1155/ijcp/7692776","DOIUrl":"https://doi.org/10.1155/ijcp/7692776","url":null,"abstract":"<div>\u0000 <p><b>Purpose:</b> This study aims to analyze the medium-term effectiveness of telerehabilitation in enhancing the quality of life for patients with Long COVID, using a mobile application (APP) called ReCOVery APP. The secondary purpose is to identify significant factors associated with an improvement in the quality of life and other secondary outcomes in this population.</p>\u0000 <p><b>Methods:</b> A randomized clinical trial was carried out with two parallel groups involving a total of 100 patients with Long COVID. The first one (control group, <i>n</i> = 48) continued with their usual treatment (TAU), established by their primary care doctor. The second one (intervention group, <i>n</i> = 52), in addition to continuing with their TAU, attended three sessions based on motivational methodology and used the ReCOVery APP for 6 months. The primary outcome was quality of life.</p>\u0000 <p><b>Results:</b> After 6 months, ReCOVery APP did not significantly improve the quality of life among Long COVID patients. Poor adherence to the APP was observed among the participants who tried it. Linear regression analyses revealed a significant relationship between the decrease in the number of symptoms and the improvement in mental health–related quality.</p>\u0000 <p><b>Conclusions:</b> While this research contributes valuable insights into the potential of telerehabilitation for Long COVID patients, the lack of significant improvement in quality of life underscores the need for future large-scale studies. Such research should focus on identifying effective strategies to enhance adherence to digital interventions, such as increased professional support and personalized care approaches. Additionally, exploring the long-term effects of telerehabilitation could provide a more comprehensive understanding of its role in managing Long COVID.</p>\u0000 <p><b>Trial Registration:</b> ISRCTN Registry identifier: ISRCTN91104012</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7692776","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143735519","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cognitive Fusion Versus Software Fusion for Subcentimeter Lesions in Transperineal mpMRI/TRUS Fusion-Guided Prostate Biopsy Under Local Anesthesia","authors":"Hejia Yuan, Peng Peng, Fan Feng, Yining Zhao, Yantao Lou, Jipeng Wang, Hongwei Zhao, Jitao Wu","doi":"10.1155/ijcp/5003501","DOIUrl":"https://doi.org/10.1155/ijcp/5003501","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> The accuracy debate between cognitive and software fusion for small lesions in multiparametric magnetic resonance imaging (mpMRI)/transrectal ultrasound (TRUS) fusion-guided prostate biopsy remains inconclusive. This study compares the diagnostic accuracy of these fusion methods for prostate cancer, specifically for lesions < 1 cm under local anesthesia.</p>\u0000 <p><b>Methods:</b> Retrospective analysis of prostate biopsies performed at The Affiliated Yantai Yuhuangding Hospital of Qingdao University (Feb 16, 2019–Feb 16, 2023). The Cognitive Fusion Group used free-hand technique for mentally integrating mpMRI and TRUS fusion, while the Software Fusion Group used MIM software with a fusion guidance grid. Lesions were defined as < 1 cm of maximum diameter on coronal using mpMRI. Each patient underwent 2–4 targeted biopsies for the identified lesion, followed by 12 systematic biopsies. All biopsies were transperineal and performed under local anesthesia.</p>\u0000 <p><b>Results:</b> Histology showed clinically significant prostate cancer (International Society of Urological Pathology ≥ 2) in 55 cases (42.6%) in the software fusion group and 66 cases (40.2%) in the cognitive fusion group within the targeted prostate cancer category. However, cognitive fusion had a shorter median operative time of 11 min compared to 22 min in the software fusion group. Complication rates did not significantly differ between the two fusion strategies.</p>\u0000 <p><b>Conclusion:</b> This study suggests that experienced operators can achieve comparable diagnostic accuracy for sub-centimeter lesions in mpMRI/TRUS fusion-guided prostate biopsy using cognitive fusion. Furthermore, cognitive fusion offers simplicity and shorter procedural time. These findings contribute to the discourse on fusion methods in prostate cancer diagnosis, and further validation studies are warranted.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/5003501","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cardiovascular Disease Management and Prevention in Saudi Arabia: Strategies, Risk Factors, and Targeted Interventions","authors":"Aseel Awad Alsaidan","doi":"10.1155/ijcp/7233591","DOIUrl":"https://doi.org/10.1155/ijcp/7233591","url":null,"abstract":"<div>\u0000 <p>Cardiovascular diseases (CVDs) remain the main cause of mortality and are generally among the leading causes of morbidity worldwide, thus placing an immense burden on health care. They include coronary artery disease, heart failure, hypertensive heart disease, and stroke. Among these, common risk factors include hypertension, high cholesterol, diabetes, smoking, obesity, and sedentary lifestyle. Yet, with advancements in medical science and pharmacology, these entities remain major challenges to public health worldwide. In Saudi Arabia, the rise in CVDs has been intensified by rapid urbanization and lifestyle changes and needs unique and tailored public health strategies. This review provides a comprehensive overview of the current situation with regard to cardiovascular health in Saudi Arabia, underlining the need for studying CVDs within the local context. It reviews the epidemiology of CVDs in the Kingdom of Saudi Arabia, outlining some of the major risk factors and also their impact on public health. This study also deals with the pharmacological approaches toward cardiovascular health by offering data from clinical trials so far completed, to point out effective strategies of treatment. The overview of prevention methods also includes public health initiatives, lifestyle programs, patient education, healthcare policies, the role of government initiatives, insurance coverage, and international collaborations. The review also elucidates the problems and barriers of the Saudi healthcare system, especially vis-à-vis the primary healthcare setting. In light of improving its healthcare sector, Saudi Arabia has embarked on several reforms within the Universal Health Coverage development initiative set in the framework of Vision 2030.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7233591","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143717370","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mengjie Fan, Li Li, Yanyi Li, Liying Wang, Hongxia Zhang, Shuo Yang, Jia Li, Ying Song, Di Sun, Danlei Zheng, Tian Tian, Caihong Ma, Ping Liu, Jie Qiao, Rui Yang, Rong Li
{"title":"Pregnancy Outcomes After Higher-Order Multifetal Pregnancy Reduction: A Retrospective Study","authors":"Mengjie Fan, Li Li, Yanyi Li, Liying Wang, Hongxia Zhang, Shuo Yang, Jia Li, Ying Song, Di Sun, Danlei Zheng, Tian Tian, Caihong Ma, Ping Liu, Jie Qiao, Rui Yang, Rong Li","doi":"10.1155/ijcp/2512443","DOIUrl":"https://doi.org/10.1155/ijcp/2512443","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> To investigate the pregnancy outcomes after transvaginal or transabdominal fetal reduction for higher-order multifetal pregnancies with four or more fetuses.</p>\u0000 <p><b>Methods:</b> This retrospective study included 102 patients with higher-order multifetal pregnancies after ovulation induction. The patients underwent fetal reduction in the Reproductive Medical Center of Peking University Third Hospital from January 2000 to December 2020. Methods of fetal reduction included transvaginal and transabdominal reduction. Pregnancy outcomes of different methods were assessed, including the live birth rate, miscarriage rate, preterm labor rate, and low birthweight rate.</p>\u0000 <p><b>Results:</b> Among these 102 patients, 84 (82.4%) underwent transvaginal fetal reduction in early pregnancy, and 18 (17.6%) underwent transabdominal reduction in the second trimester. The live birth rate (66% vs. 78%, <i>p</i> = 0.311), preterm labor rate (24% vs. 33%, <i>p</i> = 0.587), and miscarriage rate (25% vs. 17%, <i>p</i> = 0.653) were comparable for transvaginal and transabdominal fetal reduction. Age, the method of fetal reduction, and the initial number and retained number of fetuses were not influencing factors of the live birth rate or miscarriage rate in these patients.</p>\u0000 <p><b>Conclusion:</b> Prevention is the most important measure to decrease the incidence of multiple pregnancies. For higher-order multifetal pregnancies, multifetal pregnancy reduction (MFPR) is considered a significant remedial measure. Transvaginal fetal reduction in the first trimester of pregnancy and transabdominal fetal reduction in the second trimester were both safe and effective.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/2512443","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143690192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Development and Psychometric Validation of Culture of Patient Safety Scale Under Rasch Objective Measurement Theory","authors":"Odunayo Kolawole Omolade, John Stephenson","doi":"10.1155/ijcp/9997682","DOIUrl":"https://doi.org/10.1155/ijcp/9997682","url":null,"abstract":"<div>\u0000 <p><b>Background:</b> Assessing the culture of patient safety in healthcare settings is pivotal for continuously reinforcing effective, safe and quality patient care. However, most of the rating scales lack evidence of objective validation of the measuring instruments.</p>\u0000 <p><b>Aim:</b> To determine the psychometric properties of culture of patient safety scale under the Rasch objective measurement theory.</p>\u0000 <p><b>Method:</b> The validation of the culture of safety scale was underpinned by the four stages of rating scale development in Rasch objective measurement theory. The first stage involved literature review to shortlist items considered theoretically relevant to culture of patient safety in hospital settings. In the second stage, a panel of academic and practitioners individually reviewed the selected items to give external face validity based on professional experiences. In the third stage, 967 participants from public maternity settings in Nigeria voluntarily accessed the nine items forming the culture of patient safety scale online over 8-week period. Ethical approval was given by the nurses’ association and University of Huddersfield. Subsequently, all the data were exported to SPSS and Winsteps Version 5.0.0.0 for evaluation of the psychometric assumptions. Essential psychometric properties evaluated are dimensionality, category functioning, item difficulty/agreeability, local independence, reliability and item validity. In the fourth stage, problematic items were identified and moderated based on the outcome of the measurement assumptions. Consequently, final decisions made included retention, modification or expulsion of items, making no meaningful contribution to the variable measurement.</p>\u0000 <p><b>Conclusion and Implication:</b> The culture of safety scale has excellent psychometric properties and therefore recommended for use among practitioners and researchers. No direct contribution from the public or patients required in this study.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9997682","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tuğçe Yavuz Mollavelioğlu, Nurdan Paker, İlhan Karacan, Levent Özçakar
{"title":"Ultrasonographic Measurements of Femoral Cartilage Thickness in Women With Symptomatic Joint Hypermobility: A Controlled Study","authors":"Tuğçe Yavuz Mollavelioğlu, Nurdan Paker, İlhan Karacan, Levent Özçakar","doi":"10.1155/ijcp/9615146","DOIUrl":"https://doi.org/10.1155/ijcp/9615146","url":null,"abstract":"<div>\u0000 <p><b>Objective:</b> The goal of this study was to measure femoral cartilage thickness in patients with symptomatic joint hypermobility (SJH) using ultrasound (US) imaging.</p>\u0000 <p><b>Methods:</b> This cross-sectional study comprised 42 female patients diagnosed with SJH (Beighton score > 3) and 42 age-matched healthy controls. Ultrasonographic measurements of bilateral femoral cartilage thickness were conducted in three areas: medial, intercondylar, and lateral, while the patients were in a supine position with their knees fully flexed. The Numeric Pain Rating Scale and the Turkish version of the Knee Injury and Osteoarthritis Outcome Score were used to evaluate pain and functional status in the SJH group.</p>\u0000 <p><b>Results:</b> The mean age was 28.0 ± 7.1 years in the study group and 28.5 ± 7.2 years in the control group. The right medial, left medial, left intercondylar, and left lateral femoral cartilage thicknesses of patients in the SJH group were significantly thinner than those of patients in the control group (<i>p</i> < 0.05). There was no significant difference in femoral cartilage thickness, pain, and functional scores between patients with and without knee hypermobility within the SJH group (<i>p</i> > 0.05). A negative correlation was observed between femoral cartilage thickness and age, which was identified as an independent predictor of femoral cartilage thickness in SJH (<i>p</i> < 0.05).</p>\u0000 <p><b>Conclusion:</b> Femoral cartilage thickness was significantly reduced on the right/left medial, left intercondylar, and left lateral sides in women with SJH compared to healthy subjects. Furthermore, age appears to be an important determinant of femoral cartilage thickness.</p>\u0000 </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/9615146","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}