{"title":"手部水肿对ICU患者机械通气脱机的影响：一项单中心巢式病例对照研究","authors":"Dingye Wu, Junfeng Heng, Fengming Liang, Tao Zhou, Qiuhui Wang, Hongyang Xu","doi":"10.1155/ijcp/7382862","DOIUrl":null,"url":null,"abstract":"<div>\n <p><b>Objective:</b> To investigate the impact of hand edema on weaning from mechanical ventilation among ICU patients.</p>\n <p><b>Methods:</b> A nested case-control study was conducted, collecting data from mechanically ventilated patients admitted to the ICU of Wuxi People’s Hospital from October 1, 2023, to January 31, 2024. Patients were monitored for the occurrence of hand edema within the first 7 days of ICU stay and their weaning outcomes were recorded to analyze the impact of hand edema on weaning success.</p>\n <p><b>Results:</b> The study included 124 patients, 97 successfully weaned while 27 failed. The failed weaning group had higher ages (70.8 ± 10.5 years), SOFA scores (17.7 ± 3.1), and levels of hand edema (Grade 0 in 6 patients, Grade 1 in 9, Grade 2 in 6, Grade 3 in 3, and Grade 4 in 3) compared with the successful weaning group (ages 61.1 ± 9.8 years, SOFA scores 14.3 ± 3.1, hand edema levels: Grade 0 in 78, Grade 1 in 15, Grade 2 in 3, Grade 3 in 1, and Grade 4 in 0). Multivariable binary logistic regression analysis indicated that the level of hand edema is an independent risk factor for weaning failure within 1 week in ICU patients on mechanical ventilation (OR = 3.209, 95% CI: 1.641–6.274, and <i>p</i> < 0.05).</p>\n <p><b>Conclusion:</b> The occurrence of hand edema in ICU patients on mechanical ventilation increases the risk of weaning failure.</p>\n </div>","PeriodicalId":13782,"journal":{"name":"International Journal of Clinical Practice","volume":"2025 1","pages":""},"PeriodicalIF":2.2000,"publicationDate":"2025-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7382862","citationCount":"0","resultStr":"{\"title\":\"The Impact of Hand Edema on Weaning From Mechanical Ventilation in ICU Patients: A Single Center Nested Case-Control Study\",\"authors\":\"Dingye Wu, Junfeng Heng, Fengming Liang, Tao Zhou, Qiuhui Wang, Hongyang Xu\",\"doi\":\"10.1155/ijcp/7382862\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n <p><b>Objective:</b> To investigate the impact of hand edema on weaning from mechanical ventilation among ICU patients.</p>\\n <p><b>Methods:</b> A nested case-control study was conducted, collecting data from mechanically ventilated patients admitted to the ICU of Wuxi People’s Hospital from October 1, 2023, to January 31, 2024. Patients were monitored for the occurrence of hand edema within the first 7 days of ICU stay and their weaning outcomes were recorded to analyze the impact of hand edema on weaning success.</p>\\n <p><b>Results:</b> The study included 124 patients, 97 successfully weaned while 27 failed. The failed weaning group had higher ages (70.8 ± 10.5 years), SOFA scores (17.7 ± 3.1), and levels of hand edema (Grade 0 in 6 patients, Grade 1 in 9, Grade 2 in 6, Grade 3 in 3, and Grade 4 in 3) compared with the successful weaning group (ages 61.1 ± 9.8 years, SOFA scores 14.3 ± 3.1, hand edema levels: Grade 0 in 78, Grade 1 in 15, Grade 2 in 3, Grade 3 in 1, and Grade 4 in 0). Multivariable binary logistic regression analysis indicated that the level of hand edema is an independent risk factor for weaning failure within 1 week in ICU patients on mechanical ventilation (OR = 3.209, 95% CI: 1.641–6.274, and <i>p</i> < 0.05).</p>\\n <p><b>Conclusion:</b> The occurrence of hand edema in ICU patients on mechanical ventilation increases the risk of weaning failure.</p>\\n </div>\",\"PeriodicalId\":13782,\"journal\":{\"name\":\"International Journal of Clinical Practice\",\"volume\":\"2025 1\",\"pages\":\"\"},\"PeriodicalIF\":2.2000,\"publicationDate\":\"2025-02-17\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1155/ijcp/7382862\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Clinical Practice\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1155/ijcp/7382862\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Clinical Practice","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1155/ijcp/7382862","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
目的：探讨手水肿对ICU患者机械通气脱机的影响。方法：采用巢式病例对照研究，收集2023年10月1日至2024年1月31日在无锡市人民医院ICU收治的机械通气患者的资料。监测患者入住ICU前7天内手部水肿的发生情况，记录患者的脱机结果，分析手部水肿对脱机成功的影响。结果：共纳入124例患者，97例成功断奶，27例失败。脱机失败组的年龄（70.8±10.5岁）、SOFA评分（17.7±3.1）和手部水肿水平（6例为0级，9例为1级，6例为2级，3例为3级，3例为4级）均高于脱机成功组(年龄61.1±9.8岁，SOFA评分14.3±3.1，手部水肿水平：78例为0级，15例为1级，3例为2级，1例为3级，0例为4级)。多变量二元logistic回归分析显示，手部水肿程度是ICU机械通气患者1周内脱机失败的独立危险因素(OR = 3.209, 95% CI: 1.641-6.274, p <；0.05)。结论：ICU机械通气患者手部水肿的发生增加了脱机失败的风险。
The Impact of Hand Edema on Weaning From Mechanical Ventilation in ICU Patients: A Single Center Nested Case-Control Study
Objective: To investigate the impact of hand edema on weaning from mechanical ventilation among ICU patients.
Methods: A nested case-control study was conducted, collecting data from mechanically ventilated patients admitted to the ICU of Wuxi People’s Hospital from October 1, 2023, to January 31, 2024. Patients were monitored for the occurrence of hand edema within the first 7 days of ICU stay and their weaning outcomes were recorded to analyze the impact of hand edema on weaning success.
Results: The study included 124 patients, 97 successfully weaned while 27 failed. The failed weaning group had higher ages (70.8 ± 10.5 years), SOFA scores (17.7 ± 3.1), and levels of hand edema (Grade 0 in 6 patients, Grade 1 in 9, Grade 2 in 6, Grade 3 in 3, and Grade 4 in 3) compared with the successful weaning group (ages 61.1 ± 9.8 years, SOFA scores 14.3 ± 3.1, hand edema levels: Grade 0 in 78, Grade 1 in 15, Grade 2 in 3, Grade 3 in 1, and Grade 4 in 0). Multivariable binary logistic regression analysis indicated that the level of hand edema is an independent risk factor for weaning failure within 1 week in ICU patients on mechanical ventilation (OR = 3.209, 95% CI: 1.641–6.274, and p < 0.05).
Conclusion: The occurrence of hand edema in ICU patients on mechanical ventilation increases the risk of weaning failure.
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