发布求助
文献互助 智能选刊 最新文献

Internal Medicine最新文献

筛选
英文 中文
Acute Ischemic Stroke: Significance of Multimodal Pre-operative Prediction of Intracranial Atherosclerosis-Related Large Vessel Occlusion. 急性缺血性中风：多模式术前预测颅内动脉粥样硬化相关大血管闭塞的意义。
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-29 DOI: 10.2169/internalmedicine.5350-25
Kenichi Sakuta, Yasuyuki Iguchi
{"title":"Acute Ischemic Stroke: Significance of Multimodal Pre-operative Prediction of Intracranial Atherosclerosis-Related Large Vessel Occlusion.","authors":"Kenichi Sakuta, Yasuyuki Iguchi","doi":"10.2169/internalmedicine.5350-25","DOIUrl":"https://doi.org/10.2169/internalmedicine.5350-25","url":null,"abstract":"<p><p>When large-vessel occlusion (LVO) occurs in acute ischemic stroke, accurate differentiation of intracranial atherosclerosis-related occlusion (ICAD-O) from embolism-related occlusion (EMB-O) is critical for guiding treatment decisions. This review focuses on the preoperative prediction of ICAD-O and emphasizes the practical clinical and imaging factors. ICAD-O is often associated with younger age, male sex, and vascular risk factors, such as hypertension and diabetes, and the absence of atrial fibrillation is a key characteristic of its differentiation. Imaging findings, including truncal-type occlusion and non-culprit stenosis, further aid in the identification of ICAD-O. Predictive scales integrating clinical and imaging data, such as the ISAT, REMIT, ABC<sup>2</sup>D, and ATHE scores, provide structured approaches for distinguishing ICAD-O from EMB-O. By reviewing these predictive tools and findings, this review aims to enhance the accuracy and efficiency of the preoperative diagnosis, supporting better-informed clinical decision-making for stroke patients with LVO.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Difficulty in Identifying the Source of Hemorrhage in Duodenal Diverticula Bleeding: A Case Report.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-29 DOI: 10.2169/internalmedicine.5222-24
Fumioki Toyoda, Tomoaki Matsumori, Atsushi Matsumoto, Hirotaka Kashima, Sho Matsuyama, Taro Ueo, Hiroshi Seno
{"title":"Difficulty in Identifying the Source of Hemorrhage in Duodenal Diverticula Bleeding: A Case Report.","authors":"Fumioki Toyoda, Tomoaki Matsumori, Atsushi Matsumoto, Hirotaka Kashima, Sho Matsuyama, Taro Ueo, Hiroshi Seno","doi":"10.2169/internalmedicine.5222-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.5222-24","url":null,"abstract":"<p><p>Duodenal diverticular bleeding is a rare cause of upper gastrointestinal bleeding. We herein report a case of life-threatening duodenal diverticular bleeding with hypovolemic shock. Identifying the source of the hemorrhaging was difficult, and repeated endoscopic examinations-one colonoscopy and three esophagogastroduodenoscopy sessions-were required before the source was finally detected inside the diverticulum located in the third part of the duodenum. Hemostasis was successfully achieved using the hemoclips. Our case highlights the need to consider duodenal diverticulum bleeding in cases of suspected upper gastrointestinal bleeding without a clear source of bleeding.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between daily physical activity and muscle cramping in elderly liver cirrhosis patients-A multicenter study.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-29 DOI: 10.2169/internalmedicine.5189-24
Atsushi Hiraoka, Tadashi Namisaki, Masato Nakai, Nagisa Hara, Hirokazu Takahashi, Yuichiro Eguchi, Hideko Ohama, Fujimasa Tada, Naoya Sakamoto, Hitoshi Yoshiji
{"title":"Relationship between daily physical activity and muscle cramping in elderly liver cirrhosis patients-A multicenter study.","authors":"Atsushi Hiraoka, Tadashi Namisaki, Masato Nakai, Nagisa Hara, Hirokazu Takahashi, Yuichiro Eguchi, Hideko Ohama, Fujimasa Tada, Naoya Sakamoto, Hitoshi Yoshiji","doi":"10.2169/internalmedicine.5189-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.5189-24","url":null,"abstract":"<p><p>Introduction Sarcopenia is a common secondary muscle-related complication observed in patients with chronic liver disease (CLD), along with muscle cramping. The present study aimed to assess the daily activity levels to explore the relationship between the number of steps taken and muscle cramping in patients with cirrhosis (LC) in Japan. Methods Fifty patients were enrolled (male 25, Child-Pugh A, B=42:8). Daily steps were recorded over six months using a pedometer, and seasonal sub-analyses were performed. Sarcopenia was diagnosed in accordance with the guidelines of the Japan Society of Hepatology. Results The median number of steps per day was 3,881, with no significant seasonal differences. Muscle cramping, reduced handgrip strength and sarcopenia were noted in 66.0%, 34.0% and 23.9% of the patients, respectively. However, no significant relationships were found between muscle cramping, handgrip strength, and the average number of steps per day. Although no significant differences in daily steps were noted in the comparisons of patients with varying degrees of hepatic function or the sarcopenia status, those with muscle cramping had a worse modified ALBI grade (≥2b) than those without (42.4% vs. 5.9%, P=0.009). The median average number of steps per day was not significantly different between the patients with and without muscle cramping (3,673 vs. 4,775, P=0.292). Conclusions The present study revealed that the average number of steps per day in LC patients is low. Although no significant relationship between daily activity and muscle cramping was observed, the establishment of appropriate intervention strategies to maintain daily activity and prevent sarcopenia progression is urgently required.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recent Advances in Gastrointestinal Cancer Endoscopic Diagnosis and Treatment: Focusing on Older Adults.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-22 DOI: 10.2169/internalmedicine.4665-24
Taro Akashi, Naoyuki Yamaguchi, Hajime Isomoto
{"title":"Recent Advances in Gastrointestinal Cancer Endoscopic Diagnosis and Treatment: Focusing on Older Adults.","authors":"Taro Akashi, Naoyuki Yamaguchi, Hajime Isomoto","doi":"10.2169/internalmedicine.4665-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4665-24","url":null,"abstract":"<p><p>Recent advances in endoscopic equipment have improved the diagnosis of gastrointestinal tumors. Image-enhanced endoscopy, including narrow-band imaging, blue light imaging, and linked color imaging, has unified magnifying observation classification methods and significantly improved the qualitative and quantitative diagnostic performance of gastrointestinal epithelial tumors. Endoscopic submucosal dissection (ESD), a minimally invasive treatment for early-stage gastrointestinal cancer, is widely used. The aging population in Japan has been gradually increasing. Despite this, ESD has shown good outcomes in older adults. However, long-term prognostic analyses should take into account the high mortality rate from other illnesses. Prognostic indicators such as the Charlson Comorbidity Index (CCI) and the Prognostic Nutrition Index (PNI) should be used to determine whether ESD should be performed. Even in cases of noncurative resection, follow-up without additional surgical resection is an option if there are other comorbidities that affect the prognosis.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143699558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Investigation of the Number of Oral Bacteria in Patients with Chronic Obstructive Pulmonary Disease, Asthma, and Asthma and Chronic Obstructive Pulmonary Disease Overlap.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-22 DOI: 10.2169/internalmedicine.4825-24
Toshiya Inui, Maya Tsuchiya, Takayasu Watanabe, Mitsuru Sada, Atsuto Mouri, Shinkichi Iwanari, Mitsuhiro Kamimura
{"title":"Investigation of the Number of Oral Bacteria in Patients with Chronic Obstructive Pulmonary Disease, Asthma, and Asthma and Chronic Obstructive Pulmonary Disease Overlap.","authors":"Toshiya Inui, Maya Tsuchiya, Takayasu Watanabe, Mitsuru Sada, Atsuto Mouri, Shinkichi Iwanari, Mitsuhiro Kamimura","doi":"10.2169/internalmedicine.4825-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4825-24","url":null,"abstract":"<p><p>Objective Bacteria in the airways are reportedly involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) and asthma. In addition, oral bacteria are thought to contribute to respiratory diseases by migrating to the airway. Therefore, we investigated whether or not the number of oral bacteria influences COPD, asthma, and asthma and COPD overlap (ACO). Methods We analyzed the correlations between the number of oral bacteria and clinical variables, such as pulmonary function tests, in patients with COPD, asthma, and ACO whose condition was stable and who visited our center from August 2019 to December 2020. The number of oral bacteria was assessed using the dielectrophoretic impedance measurement method. Results In patients with COPD (n = 50), the number of oral bacteria was significantly negatively correlated with the percentage predicted forced expiratory volume in one second (%FEV<sub>1</sub>), percentage peak expiratory flow, and percentage forced vital capacity but was not correlated with the COPD Assessment Test. In patients with asthma (n = 32), it was significantly negatively correlated with the FEV<sub>1</sub> percentage and with the increase in FEV<sub>1</sub> in the reversibility test but not with fractional exhaled nitric oxide. In patients with ACO (n = 39), we found no significant correlation between the number of oral bacteria and any clinical variable. Conclusion The results suggest that the number of oral bacteria is associated with both lung capacity and airflow obstruction in patients with COPD and with airflow obstruction in patients with asthma.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Status Epilepticus Caused by Tick-borne Encephalitis: A Case Report.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-22 DOI: 10.2169/internalmedicine.4773-24
Kazuhiro Horiuchi, Shuntaro Nakamura, Kazuki Yamada, Kazuya Mitsuhashi, Kei Watari, Kazuma Tamiya, Hiroki Yamaguchi, Shintaro Kobayashi
{"title":"Status Epilepticus Caused by Tick-borne Encephalitis: A Case Report.","authors":"Kazuhiro Horiuchi, Shuntaro Nakamura, Kazuki Yamada, Kazuya Mitsuhashi, Kei Watari, Kazuma Tamiya, Hiroki Yamaguchi, Shintaro Kobayashi","doi":"10.2169/internalmedicine.4773-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4773-24","url":null,"abstract":"<p><p>We herein report a rare case of a 78-year-old Japanese man who developed refractory status epilepticus due to tick-borne encephalitis (TBE). The patient initially presented with left-sided hemiplegia and loss of consciousness. Initial diagnostic tests could not identify the cause of the encephalomyelitis, leading to a preliminary diagnosis of autoimmune encephalomyelitis. Despite treatment with corticosteroids and plasma exchange, the patient experienced status epilepticus, which required multiple antiseizure medications. TBE viral antibodies were eventually detected, confirming the diagnosis. Despite the treatment, the patient remained critically ill. Clinicians should consider TBE in the differential diagnosis of encephalitis of unknown origin associated with status epilepticus.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
New-onset Fulminant Type 1 Diabetes Following COVID-19 Vaccination.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-22 DOI: 10.2169/internalmedicine.5053-24
Takaaki Shigematsu, Yu Yamaguchi, Takeo Watanabe, Kazutaka Tsujimoto, Fuminori Sato, Tetsuya Yamada, Motoyoshi Tsujino
{"title":"New-onset Fulminant Type 1 Diabetes Following COVID-19 Vaccination.","authors":"Takaaki Shigematsu, Yu Yamaguchi, Takeo Watanabe, Kazutaka Tsujimoto, Fuminori Sato, Tetsuya Yamada, Motoyoshi Tsujino","doi":"10.2169/internalmedicine.5053-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.5053-24","url":null,"abstract":"<p><p>A 31-year-old Japanese man was admitted with a slight fever and epigastric pain. He had received his third Moderna COVID-19 vaccine dose (Spikevax, mRNA-1273) 16 days before his visit. His serum amylase level was elevated, and computed tomography (CT) found pancreatic enlargement. Acute pancreatitis was diagnosed, and the patient was treated with fasting and intravenous fluids. However, on day 3 of hospitalization, his blood glucose level had increased to 320 mg/dL. His serum and urinary C-peptide were remarkably low (≤0.03 ng/mL and ≤0.6 μg/day, respectively) Finally, fulminant type 1 diabetes mellitus caused by the COVID-19 mRNA vaccine was diagnosed.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Graves' Disease after Resection of an Autonomously Functioning Thyroid Nodule.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-22 DOI: 10.2169/internalmedicine.4597-24
Shigenori Nakamura
{"title":"Development of Graves' Disease after Resection of an Autonomously Functioning Thyroid Nodule.","authors":"Shigenori Nakamura","doi":"10.2169/internalmedicine.4597-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4597-24","url":null,"abstract":"<p><p>We herein report a 46-year-old woman with autonomously functioning thyroid nodules (AFTNs) who developed Graves' disease (GD) approximately one year after AFTN resection. Before surgery, the patient was positive for TgAb and TPOAb, and negative for TRAb. An AFTN is a follicular adenoma surrounded by chronic thyroiditis. At the onset of GD, her TgAb and TPOAb titers increased, and TRAb became positive. This case suggests that surgery releases a large amount of thyroid tissue that contains thyroid-stimulating hormone receptors, leading to GD in susceptible individuals. Preoperative chronic thyroiditis can predict the postoperative development of GD.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Hereditary Factor XI Deficiency Accompanied by Lupus Anticoagulant in an Adult Patient with Monoclonal Gammopathy of Undetermined Significance.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-22 DOI: 10.2169/internalmedicine.5113-24
Hengwei Liu
{"title":"A Rare Case of Hereditary Factor XI Deficiency Accompanied by Lupus Anticoagulant in an Adult Patient with Monoclonal Gammopathy of Undetermined Significance.","authors":"Hengwei Liu","doi":"10.2169/internalmedicine.5113-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.5113-24","url":null,"abstract":"<p><p>Acquired coagulopathy, particularly bleeding due to factor X deficiency, is a rare but not unusual phenomenon in patients with plasma cell dyscrasias such as amyloidosis. We herein report a rare case of a Han Chinese man with recurrent scattered skin ecchymosis on the forearms due to factor XI (FXI) deficiency and lupus anticoagulant who was diagnosed with monoclonal gammopathy of undetermined significance (MGUS) and confirmed to have a heterozygous mutation p.L190P (c.T569C) in the FXI gene. To our knowledge, this is the first case report of MGUS concurrent with a FXI missense mutation and lupus anticoagulant.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
High-altitude Pulmonary Edema on Mt. Fuji Requires Exclusion of all Differential Diagnoses.
IF 1 4区 医学
Internal Medicine Pub Date : 2025-03-22 DOI: 10.2169/internalmedicine.5392-25
Josef Finsterer
{"title":"High-altitude Pulmonary Edema on Mt. Fuji Requires Exclusion of all Differential Diagnoses.","authors":"Josef Finsterer","doi":"10.2169/internalmedicine.5392-25","DOIUrl":"https://doi.org/10.2169/internalmedicine.5392-25","url":null,"abstract":"","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700403","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页 下一页 尾页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信