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Acute Severe Colitis after mRNA Coronavirus Disease 2019 Vaccination. 接种 mRNA 冠状病毒疾病 2019 疫苗后出现急性严重结肠炎：病例报告。
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-11-08 DOI: 10.2169/internalmedicine.4224-24
Akira Nakanishi, Sakuma Takahashi, Tomoki Inaba, Eriko Yasutomi, Hugh Shunsuke Colvin, Koichi Izumikawa, Shigenao Ishikawa, Masaki Wato, Midori Ando, Satoko Nakamura
{"title":"Acute Severe Colitis after mRNA Coronavirus Disease 2019 Vaccination.","authors":"Akira Nakanishi, Sakuma Takahashi, Tomoki Inaba, Eriko Yasutomi, Hugh Shunsuke Colvin, Koichi Izumikawa, Shigenao Ishikawa, Masaki Wato, Midori Ando, Satoko Nakamura","doi":"10.2169/internalmedicine.4224-24","DOIUrl":"10.2169/internalmedicine.4224-24","url":null,"abstract":"<p><p>A 74-year-old woman developed acute severe colitis after receiving her sixth mRNA vaccine against coronavirus disease 2019 (COVID-19). On the day after vaccination, she experienced bloody diarrhea, abdominal pain, and high-grade fever. Laboratory tests revealed leukocytosis and increased C-reactive protein. Contrast-enhanced computed tomography revealed bowel wall thickening with a reduced contrast effect within the colon, in addition to ascites. Sigmoidoscopy revealed extensive sloughing of the mucosa. Her symptoms and laboratory findings improved immediately after the initiation of prednisolone therapy. Pre-discharge total colonoscopy revealed mucosal repair in most of the colon. Clinicians should acknowledge that severe acute colitis can occur after COVID-19 vaccination.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"201-207"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Multimodality Imaging in Detecting Cardiac Masses in Patients with Lymphoma. 多模态成像检测淋巴瘤患者的心脏肿块
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-06-06 DOI: 10.2169/internalmedicine.3985-24
Yusuf Ziya Sener
{"title":"Multimodality Imaging in Detecting Cardiac Masses in Patients with Lymphoma.","authors":"Yusuf Ziya Sener","doi":"10.2169/internalmedicine.3985-24","DOIUrl":"10.2169/internalmedicine.3985-24","url":null,"abstract":"","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"325"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141260288","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Delayed Superior Orbital Fissure Syndrome Arising More than One Month after Herpes Zoster Ophthalmicus and Meningitis. 带状疱疹眼炎和脑膜炎一个多月后出现的延迟性眼眶上裂综合征。
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-06-06 DOI: 10.2169/internalmedicine.3652-24
Sunao Takahashi, Kotaro Okabayashi, Itsuki Soejima, Ayako Oniki, Shoichiro Ishihara, Hiroyuki Tomimitsu
{"title":"Delayed Superior Orbital Fissure Syndrome Arising More than One Month after Herpes Zoster Ophthalmicus and Meningitis.","authors":"Sunao Takahashi, Kotaro Okabayashi, Itsuki Soejima, Ayako Oniki, Shoichiro Ishihara, Hiroyuki Tomimitsu","doi":"10.2169/internalmedicine.3652-24","DOIUrl":"10.2169/internalmedicine.3652-24","url":null,"abstract":"<p><p>A 79-year-old woman developed herpes zoster ophthalmicus (HZO) with a vesicular rash on the nasal root, which developed soon after intravenous acyclovir therapy. Although varicella zoster virus DNA was undetectable in the cerebrospinal fluid, she presented with ophthalmoplegia without optic nerve dysfunction 32 days after the onset of HZO. We diagnosed the patient with superior orbital fissure syndrome and administered intravenous immunoglobulin and systemic corticosteroids. Ophthalmoplegia did not immediately respond to these therapies but resolved 4 months later. We should be aware that ophthalmoplegia can occur, even after HZO and meningitis are completely treated.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"293-296"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141260285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Extensive but Steroid-sensitive Pulmonary Infiltration by Natural Killer-large Granular Lymphocytic Leukemia. 自然杀伤型大颗粒淋巴细胞白血病广泛但类固醇敏感的肺浸润。
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 DOI: 10.2169/internalmedicine.4714-24
Masahiro Tokunaga, Satoshi Tetsumoto, Hayato Maruoka, Akito Miyazaki, Shinichi Yoshikawa, Tetsuo Maeda
{"title":"Extensive but Steroid-sensitive Pulmonary Infiltration by Natural Killer-large Granular Lymphocytic Leukemia.","authors":"Masahiro Tokunaga, Satoshi Tetsumoto, Hayato Maruoka, Akito Miyazaki, Shinichi Yoshikawa, Tetsuo Maeda","doi":"10.2169/internalmedicine.4714-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4714-24","url":null,"abstract":"<p><p>A 51-year-old woman with persistent proliferation of natural killer (NK) cells in her peripheral blood was diagnosed with NK-large granular lymphocytic leukemia (NK-LGLL). During follow-up, computed tomography revealed multiple infiltrative pulmonary lesions. A flow cytometric analysis of bronchoalveolar lavage fluid showed infiltration of NK cells, resulting in a diagnosis of pulmonary infiltration by NK-LGLL. A histological examination of thoracoscopic lung biopsy specimens supported this diagnosis. She was started on 1 mg/kg prednisolone, which resulted in a durable reduction in these lesions. This is the first report of a NK-LGLL patient with pulmonary infiltration who received medication. Furthermore, treatment with prednisolone alone was successful.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intravenous Thrombolysis for Pediatric Ischemic Stroke Secondary to Cancer Therapy-related Cardiac Dysfunction. 静脉溶栓治疗癌症治疗相关心功能障碍继发的小儿缺血性中风：病例报告。
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-05-30 DOI: 10.2169/internalmedicine.3755-24
Futoshi Eto, Tomohisa Nezu, Hideaki Sakahara, Yumiko Yamamoto, Shiro Aoki, Maiko Shimomura, Shuhei Karakawa, Hirofumi Maruyama
{"title":"Intravenous Thrombolysis for Pediatric Ischemic Stroke Secondary to Cancer Therapy-related Cardiac Dysfunction.","authors":"Futoshi Eto, Tomohisa Nezu, Hideaki Sakahara, Yumiko Yamamoto, Shiro Aoki, Maiko Shimomura, Shuhei Karakawa, Hirofumi Maruyama","doi":"10.2169/internalmedicine.3755-24","DOIUrl":"10.2169/internalmedicine.3755-24","url":null,"abstract":"<p><p>An 11-year-old boy developed cardioembolic stroke (CES) and cancer therapy-related cardiac dysfunction (CTRCD). He originally developed Ewing sarcoma and was treated with high-dose chemotherapy including doxorubicin. On admission, he had severe aphasia, and magnetic resonance imaging showed occlusion of the left middle cerebral artery M3 segment. Transthoracic echocardiography revealed severe left ventricular dysfunction and a mobile thrombus at the left ventricular apex. Intravenous thrombolysis was administered, and effective recanalization was achieved. The patient did not exhibit any neurological deficits during discharge. Reperfusion therapy for pediatric patients has not yet been established; however, it may be effective for CES secondary to CTRCD.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"287-291"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141175625","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Acute Hemorrhagic Leukoencephalitis with Concurrent Retinal Vasculitis in an Elderly Japanese Patient. 一名日本老年患者的急性出血性白脑炎并发视网膜血管炎：病例报告。
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-06-20 DOI: 10.2169/internalmedicine.3518-24
Yoshitaka Yamaguchi, Ryosuke Sawaya, Natsuko Shichinohe, Zen-Ichi Tanei, Maeho Yamasaki, Fumiki Tomeoka, Minoru Ajiki, Tatsuro Takada, Toshiya Shinohara, Katsuyuki Asaoka
{"title":"Acute Hemorrhagic Leukoencephalitis with Concurrent Retinal Vasculitis in an Elderly Japanese Patient.","authors":"Yoshitaka Yamaguchi, Ryosuke Sawaya, Natsuko Shichinohe, Zen-Ichi Tanei, Maeho Yamasaki, Fumiki Tomeoka, Minoru Ajiki, Tatsuro Takada, Toshiya Shinohara, Katsuyuki Asaoka","doi":"10.2169/internalmedicine.3518-24","DOIUrl":"10.2169/internalmedicine.3518-24","url":null,"abstract":"<p><p>A 68-year-old Japanese man developed a fever, headache, hiccups, and altered consciousness. Brain magnetic resonance imaging revealed a hemorrhagic lesion in the right temporal lobe and multiple high-intensity white matter lesions. A brain biopsy showed pathological findings consistent with acute disseminated encephalomyelitis (ADEM), suggesting a diagnosis of acute hemorrhagic leukoencephalitis (AHLE), an aggressive ADEM variant. The patient also developed myodesopsia and was diagnosed with retinal vasculitis, likely due to a hyperimmune state caused by AHLE. Corticosteroids enabled full recovery. Although AHLE is uncommon in elderly individuals, clinicians should be aware of its occurrence in this patient subgroup and recognize potential retinal manifestations associated with AHLE.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"301-306"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141426785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pseudogout Localized to the Pubic Symphysis. 耻骨联合局部假性痛风
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-05-23 DOI: 10.2169/internalmedicine.3825-24
Jun Nishinarita, Tomoya Tsuchida, Hirotoshi Fujii, Yoshiyuki Ohira
{"title":"Pseudogout Localized to the Pubic Symphysis.","authors":"Jun Nishinarita, Tomoya Tsuchida, Hirotoshi Fujii, Yoshiyuki Ohira","doi":"10.2169/internalmedicine.3825-24","DOIUrl":"10.2169/internalmedicine.3825-24","url":null,"abstract":"","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"321"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141081210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical Limitations of Vasoreactivity Testing as a Diagnostic Tool in Patients with Vasospastic Angina. 将血管活性测试作为血管痉挛性心绞痛患者诊断工具的临床局限性
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-05-30 DOI: 10.2169/internalmedicine.3567-24
Shozo Sueda, Yutaka Hayashi
{"title":"Clinical Limitations of Vasoreactivity Testing as a Diagnostic Tool in Patients with Vasospastic Angina.","authors":"Shozo Sueda, Yutaka Hayashi","doi":"10.2169/internalmedicine.3567-24","DOIUrl":"10.2169/internalmedicine.3567-24","url":null,"abstract":"<p><p>The Japanese Circulation Society guidelines recommend a class I vasoreactivity test to diagnose patients with vasospastic angina (VSA). However, the acetylcholine or ergonovine test has been established as the gold standard for variant angina (VA). The sensitivity and specificity of intracoronary vasoreactivity testing in patients with VA were acceptable. Cardiologists have employed these vasoreactivity tests to conveniently diagnose the presence of coronary spasms in patients with all VSA. The majority of VSAs may have lower disease activity than VA cases. We have summarized the usefulness of spasm provocation tests in patients with VA and VSA. A positive-provoked spasm diagnosed by standard vasoreactivity testing may indicate a disease state similar to that of VA, whereas a negative-provoked spasm after standard vasoreactivity testing may indicate a lower disease state than that of VA. Cardiologists should reconsider the limited usefulness of vasoreactivity testing when diagnosing the presence of coronary spasms in all VSAs, but not VA.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"171-175"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141175618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Successful Treatment of Bilocular Walled-off Necrosis with Transmural Naso-cyst Continuous Irrigation. 经壁鼻腔-囊肿连续灌洗成功治疗双眼球壁脱落坏死：病例报告
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 Epub Date: 2024-06-06 DOI: 10.2169/internalmedicine.3770-24
Mari Matsuyama, Hisanori Matsuzawa, Kazuya Kimura, Yuki Izumiya, Kae Sugawara, Satoko Tsuda, Tsuyotoshi Tuji, Kunio Nakane, Masafumi Komatsu, Katsunori Iijima
{"title":"Successful Treatment of Bilocular Walled-off Necrosis with Transmural Naso-cyst Continuous Irrigation.","authors":"Mari Matsuyama, Hisanori Matsuzawa, Kazuya Kimura, Yuki Izumiya, Kae Sugawara, Satoko Tsuda, Tsuyotoshi Tuji, Kunio Nakane, Masafumi Komatsu, Katsunori Iijima","doi":"10.2169/internalmedicine.3770-24","DOIUrl":"10.2169/internalmedicine.3770-24","url":null,"abstract":"<p><p>Recently, transmural naso-cyst continuous irrigation (TNCCI) has been reported as an effective and safe treatment for walled-off necrosis (WON). We herein report a case of bilocular WON that was successfully treated with TNCCI. The patient was a 60-year-old man. The patient underwent endoscopic ultrasound-guided cyst drainage of the main cavity and subcavity using a single transluminal gateway transcystic multiple drainage technique, which was ineffective. Subsequently, a lumen-apposing metal stent (LAMS) was placed in the main cavity and TNCCI was successfully performed in the subcavity. TNCCI with LAMS was effective in treating bilocular WON.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"195-200"},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141260292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occlusion of Dorsalis Pedis Artery in an Athlete. 运动员足背动脉闭塞。
IF 1 4区 医学
Internal Medicine Pub Date : 2025-01-15 DOI: 10.2169/internalmedicine.4584-24
Ryohei Akashi, Hiroaki Kawano, Satoshi Ikeda, Koji Maemura
{"title":"Occlusion of Dorsalis Pedis Artery in an Athlete.","authors":"Ryohei Akashi, Hiroaki Kawano, Satoshi Ikeda, Koji Maemura","doi":"10.2169/internalmedicine.4584-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4584-24","url":null,"abstract":"<p><p>A 17-year-old Japanese boy was admitted to our hospital with intermittent claudication. He belonged to a weightlifting team at a high school. He had occasionally dropped lightweight lifting weights on his right foot. Arteriography of the right anterior and posterior tibial arteries revealed a 4-cm total occlusion in the right dorsalis pedis artery (DPA). Intravascular ultrasonography revealed intimal thickening and thrombus formation He was diagnosed with thrombus occlusion of the right DPA due to intimal artery damage caused by lightweight weightlifting. DPA thrombosis may occur in young athletes who do not have atherosclerosis or vasculitis.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143004810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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