发布求助
文献互助 智能选刊 最新文献

Internal Medicine最新文献

筛选
英文 中文
Immunoglobulin G4-related autoimmune hepatitis following type 1 autoimmune pancreatitis: A case report and literature review. 1 型自身免疫性胰腺炎后出现免疫球蛋白 G4 相关自身免疫性肝炎：病例报告和文献综述。
IF 1 4区 医学
Internal Medicine Pub Date : 2024-11-08 DOI: 10.2169/internalmedicine.4687-24
Chiharu Toh, Shinichi Morita, Nobutaka Takeda, Fusako Yamazaki, Kunihiko Yokoyama, Masatoshi Sato, Daisuke Kumaki, Takeshi Sakai, Kazuhiro Funakoshi, Koichi Tsuneyama
{"title":"Immunoglobulin G4-related autoimmune hepatitis following type 1 autoimmune pancreatitis: A case report and literature review.","authors":"Chiharu Toh, Shinichi Morita, Nobutaka Takeda, Fusako Yamazaki, Kunihiko Yokoyama, Masatoshi Sato, Daisuke Kumaki, Takeshi Sakai, Kazuhiro Funakoshi, Koichi Tsuneyama","doi":"10.2169/internalmedicine.4687-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4687-24","url":null,"abstract":"<p><p>We herein report a case of IgG4-related autoimmune hepatitis (AIH) in a patient with a history of type 1 autoimmune pancreatitis. A 56-year-old man presented with fatigue and jaundice at our hospital. A blood biochemistry analysis revealed significant liver dysfunction, positive results for antinuclear antibodies, and high serum IgG4 levels. A histopathological examination revealed interface hepatitis marked by IgG4-positive plasma cell infiltration in the portal area, leading to liver cell depletion and necrosis. Based on the diagnosis of IgG4-related AIH, prednisolone treatment was initiated, which led to the rapid resolution of liver dysfunction and jaundice. An accurate diagnosis of IgG4-related AIH is crucial to prevent secondary manifestations.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lobectomy for Anomalous Systemic Arterial Supply to the Basal Segment of the Lung in the Second Trimester of a Pregnant Patient with Hemoptysis. 为一名咯血的孕妇进行肺叶切除术，以治疗第二孕期肺基底段系统动脉供应异常。
IF 1 4区 医学
Internal Medicine Pub Date : 2024-11-08 DOI: 10.2169/internalmedicine.4283-24
Mio Sugino, Manabu Suzuki, Mikako Nakamura, Hiroto Hatano, Misao Nakanishi, Kento Misumi, Satoshi Nagasaka, Shinyu Izumi, Masayuki Hojo, Haruhito Sugiyama
{"title":"Lobectomy for Anomalous Systemic Arterial Supply to the Basal Segment of the Lung in the Second Trimester of a Pregnant Patient with Hemoptysis.","authors":"Mio Sugino, Manabu Suzuki, Mikako Nakamura, Hiroto Hatano, Misao Nakanishi, Kento Misumi, Satoshi Nagasaka, Shinyu Izumi, Masayuki Hojo, Haruhito Sugiyama","doi":"10.2169/internalmedicine.4283-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4283-24","url":null,"abstract":"<p><p>An anomalous systemic arterial supply to the basal segment of the lung (ABLL) is a rare congenital vascular anomaly. We herein report a case of ABLL in a 26-year-old pregnant woman with hemoptysis. Contrast-enhanced chest computed tomography (CT) revealed an abnormal vessel branching directly from the descending aorta and circulating to the left lower lobe while showing a normal bronchial anatomy. The patient was therefore diagnosed with ABLL. Maternal safety was a priority, and the patient underwent thoracoscopic left lower lobectomy at 19 weeks' gestation. We concluded that the hemoptysis had been caused by an increased circulating plasma volume during pregnancy.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Localized Unresectable Thymic Carcinoma Treated with Induction Chemotherapy with Lenvatinib before Radiotherapy: A Case Report. 放疗前使用乐伐替尼诱导化疗治疗局部未切除胸腺癌：病例报告。
IF 1 4区 医学
Internal Medicine Pub Date : 2024-11-08 DOI: 10.2169/internalmedicine.4383-24
Shodai Fujimoto, Naoko Katsurada, Rie Sasaki, Takeaki Ishihara, Daisuke Hazama, Masatsugu Yamamoto, Motoko Tachihara
{"title":"Localized Unresectable Thymic Carcinoma Treated with Induction Chemotherapy with Lenvatinib before Radiotherapy: A Case Report.","authors":"Shodai Fujimoto, Naoko Katsurada, Rie Sasaki, Takeaki Ishihara, Daisuke Hazama, Masatsugu Yamamoto, Motoko Tachihara","doi":"10.2169/internalmedicine.4383-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4383-24","url":null,"abstract":"<p><p>Thymic carcinoma (TC) is a rare malignancy with limited treatment options. Lenvatinib, a novel multitarget kinase inhibitor, has recently been used to treat advanced or metastatic thymic carcinoma that cannot be surgically removed. To date, there have been no reports of lenvatinib being used as induction chemotherapy prior to radiotherapy in cases of localized, unresectable thymic carcinoma. We herein report an 85-year-old Japanese woman with localized unresectable thymic carcinoma who was treated with lenvatinib as induction chemotherapy before undergoing radiotherapy. Our findings suggest that lenvatinib may be a viable option for induction chemotherapy in similar clinical scenarios.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prophylaxis Against Central Nervous System Relapse in Methotrexate-associated Intravascular Large B-cell Lymphoma. 预防甲氨蝶呤相关血管内大 B 细胞淋巴瘤的中枢神经系统复发
IF 1 4区 医学
Internal Medicine Pub Date : 2024-11-08 DOI: 10.2169/internalmedicine.4692-24
Kohei Shiroshita
{"title":"Prophylaxis Against Central Nervous System Relapse in Methotrexate-associated Intravascular Large B-cell Lymphoma.","authors":"Kohei Shiroshita","doi":"10.2169/internalmedicine.4692-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4692-24","url":null,"abstract":"","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ulcerative Colitis in Pregnancy: A Japanese Multicenter Cohort Study Focusing on Their Mutual Influence. 妊娠期溃疡性结肠炎：一项日本多中心队列研究，聚焦它们之间的相互影响。
IF 1 4区 医学
Internal Medicine Pub Date : 2024-11-08 DOI: 10.2169/internalmedicine.4347-24
Yuichi Shimodate, Akiko Shiotani, Ken-Ichi Tarumi, Hiroshi Matsumoto, Osamu Handa, Noriaki Tomioka, Naoyuki Nishimura, Kazuhiro Matsueda, Hirokazu Mouri, Motowo Mizuno
{"title":"Ulcerative Colitis in Pregnancy: A Japanese Multicenter Cohort Study Focusing on Their Mutual Influence.","authors":"Yuichi Shimodate, Akiko Shiotani, Ken-Ichi Tarumi, Hiroshi Matsumoto, Osamu Handa, Noriaki Tomioka, Naoyuki Nishimura, Kazuhiro Matsueda, Hirokazu Mouri, Motowo Mizuno","doi":"10.2169/internalmedicine.4347-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4347-24","url":null,"abstract":"<p><p>Objective To investigate the clinical course of ulcerative colitis (UC) during pregnancy, focusing on their mutual influence. Methods We retrospectively reviewed the medical records of 58 patients with UC who had 73 pregnancies and 3 patients with newly developed UC during pregnancy. We recorded the rate of relapse of UC; the relationship between medication use and UC relapse during pregnancy; treatment for relapse; and the incidence of pregnancy, childbirth, and newborn abnormalities. Results UC was in remission at conception in 78% of the patients. The relapse rate during pregnancy was 27.3%, with most relapses occurring during the second and third trimesters. The relapse rate in patients in whom any UC drug had been discontinued was 50%, a rate significantly higher than the 20.5% of patients for whom all medications were continued (p = 0.016). Thiopurine was discontinued in 60% (6/10) of patients at conception, and the disease relapsed in 50% (3/6) of the patients. Most relapses were successfully treated with 5-aminosalicylic acid or corticosteroids. UC relapse occurred in 26.1% (18/70) of the patients after delivery, mostly within 2 months. Pregnancy, delivery, or neonatal abnormalities occurred in 23.3% (17/73) of patients. In two of the three patients with new-onset UC, UC was severe and required intensive care; however, the pregnancies continued uneventfully. Conclusion Although the progress of pregnancies complicated by UC was mostly uneventful, discontinuing medication carries the risk of UC relapse. Thus, appropriate management of medical treatments for UC during pregnancy is important.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Rare Case of Primary Hepatic Undifferentiated Pleomorphic Sarcoma: Exploring Cancer-related Gene Mutations. 原发性肝未分化多形性肉瘤罕见病例：探索癌症相关基因突变。
IF 1 4区 医学
Internal Medicine Pub Date : 2024-11-08 DOI: 10.2169/internalmedicine.4368-24
Hiroyuki Suzuki, Michitaka Fukuda, Tomotake Shirono, Reiichiro Kondo, Toshimitsu Tanaka, Takashi Niizeki, Jun Akiba, Hironori Koga, Takumi Kawaguchi
{"title":"A Rare Case of Primary Hepatic Undifferentiated Pleomorphic Sarcoma: Exploring Cancer-related Gene Mutations.","authors":"Hiroyuki Suzuki, Michitaka Fukuda, Tomotake Shirono, Reiichiro Kondo, Toshimitsu Tanaka, Takashi Niizeki, Jun Akiba, Hironori Koga, Takumi Kawaguchi","doi":"10.2169/internalmedicine.4368-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4368-24","url":null,"abstract":"<p><p>Hepatic undifferentiated pleomorphic sarcoma (UPS) is a rare malignant mesenchymal tumor with unclear cancer-related genetic mutations. In a 60-year-old Japanese woman with a rapidly growing, inoperable hepatic UPS, a genetic mutation analysis revealed KRAS and TP53 mutations. Despite initiating hepatic arterial infusion chemotherapy, the tumor continued to grow, and the patient's poor performance status complicated the transition to a phase I KRAS mutation drug trial, leading to death eight months after the symptom onset. A timely genetic mutation analysis may facilitate effective treatment transitions in hepatic UPS despite the lack of established treatments.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619685","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Vessel Wall Magnetic Resonance Imaging Showing Intravascular Large B-cell Lymphoma Infiltration: Association with Pathological Findings. 血管壁磁共振成像显示血管内大 B 细胞淋巴瘤浸润：与病理结果的关联
IF 1 4区 医学
Internal Medicine Pub Date : 2024-11-08 DOI: 10.2169/internalmedicine.4559-24
Masaomi Yamamoto, Tomohisa Dembo, Keisuke Sawada, Baku Hashimoto, Satoru Ouji, Kenichi Kaida
{"title":"Vessel Wall Magnetic Resonance Imaging Showing Intravascular Large B-cell Lymphoma Infiltration: Association with Pathological Findings.","authors":"Masaomi Yamamoto, Tomohisa Dembo, Keisuke Sawada, Baku Hashimoto, Satoru Ouji, Kenichi Kaida","doi":"10.2169/internalmedicine.4559-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.4559-24","url":null,"abstract":"<p><p>A 75-year-old man presented with cognitive decline, headaches, and ataxic gait. Magnetic resonance imaging (MRI) revealed acute infarcts in multiple brain regions, and vessel wall MRI (VW-MRI) demonstrated concentric arterial wall thickening and enhancement in some intracranial arteries, initially suggesting primary central nervous system vasculitis (PCNSV). Despite immunosuppressive therapy, the patient developed further infarction. A skin biopsy revealed intravascular large B-cell lymphoma (IVLBCL), and autopsy revealed tumor cells in the arterial walls corresponding to the VW-MRI findings. This case highlights the risk of a misdiagnosis of PCNSV based solely on imaging findings and underscores the need for histological confirmation.</p>","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142619780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pembrolizumab-induced Immune-related Bilateral Vocal Cord Paralysis. Pembrolizumab 引发的免疫相关性双侧声带麻痹。
IF 1 4区 医学
Internal Medicine Pub Date : 2024-01-01 Epub Date: 2024-11-15 DOI: 10.2169/internalmedicine.3599-24
Taichi Nomura, Ikuko Iwata, Shogo Kimura, Ichiro Yabe
{"title":"Pembrolizumab-induced Immune-related Bilateral Vocal Cord Paralysis.","authors":"Taichi Nomura, Ikuko Iwata, Shogo Kimura, Ichiro Yabe","doi":"10.2169/internalmedicine.3599-24","DOIUrl":"https://doi.org/10.2169/internalmedicine.3599-24","url":null,"abstract":"","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":null,"pages":null},"PeriodicalIF":1.0,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142647965","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：481959085
Book学术官方微信