Internal Medicine最新文献_第3页

Intravenous Methylprednisolone for Acute Right Middle Cerebral Artery Occlusion in Granulomatosis Polyangiitis. 静脉注射甲基强的松龙治疗肉芽肿性多血管炎急性右大脑中动脉闭塞1例。

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-15 Epub Date: 2025-04-12 DOI: 10.2169/internalmedicine.4873-24

Tsubasa Watanabe, Nakako Tanaka-Mabuchi, Yuto Morishima, Takanori Hata, Ryosuke Ito, Sho Nakajima, Atsuhiko Shindo, Yuki Nakamura, Hideyuki Yoshioka, Koji Hashimoto, Kazumasa Shindo, Hiroyuki Kinouchi, Daiki Nakagomi, Yuji Ueno

引用次数: 0

Radiation-induced Osteosarcoma in the Thoracic Cavity 28 Years after Irradiation for a Benign Disease: An Autopsy Case. 良性疾病放疗后28年胸腔内放射诱发的骨肉瘤：一个尸检病例。

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-15 Epub Date: 2025-04-12 DOI: 10.2169/internalmedicine.5162-24

Shima Sunanaga, Yusuke Sunanaga, Hirotaka Uto, Jiro Nakashioya, Takafumi Hamada, Yusuke Fujino, Shuya Tanaka

引用次数: 0

Coexistence of Relapsing Polychondritis, Crohn's Disease, and Pyoderma Gangrenosum Treated Successfully with Adalimumab: A Case Report and Literature Review. 阿达木单抗成功治疗复发性多软骨炎、克罗恩病和坏疽性脓皮病的共存：一例报告和文献综述

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-15 Epub Date: 2025-03-22 DOI: 10.2169/internalmedicine.5024-24

Shun Yamazaki, Kentaro Tominaga, Kotaro Watanabe, Makoto Watanabe, Shuhei Kondo, Norihiro Sakai, Tomoaki Yoshida, Yuichi Kojima, Yusuke Watanabe, Yuzo Kawata, Naruhiro Kimura, Kazuya Takahashi, Hiroki Sato, Satoshi Ikarashi, Hiroteru Kamimura, Kazunao Hayashi, Shuji Terai

引用次数: 0

Varicella-zoster Virus Reactivation with Severe Pneumonia Following Convalescence from Coronavirus Disease: A Case Report and Literature Review. 冠状病毒病恢复期并发严重肺炎的水痘带状疱疹病毒再激活1例报告并文献复习。

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-15 Epub Date: 2025-04-05 DOI: 10.2169/internalmedicine.4932-24

Reo Tome, Seishiro Arima, Morikazu Akamine, Hiroe Hashioka, Wakako Arakaki, Wakaki Kami, Daijiro Nabeya, Shuhei Ideguchi, Hideta Nakamura, Takeshi Kinjo, Masashi Nakamatsu, Makoto Furugen, Kazuya Miyagi, Syusaku Haranaga, Kazuko Yamamoto

引用次数: 0

Deep Neck Infection Caused by Pseudomonas aeruginosa. 铜绿假单胞菌所致深颈部感染1例。

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-15 Epub Date: 2025-04-12 DOI: 10.2169/internalmedicine.4756-24

Yuichiro Iwamoto, Ryo Shirai, Katsumasa Koyama, Yoshinori Fujita, Masako Uno, Koichi Tomoda, Takeshi Akisada

引用次数: 0

The Serum γ-Glutamyltransferase Level Is Associated with the Development of Hypertension in Alcohol Infrequent Drinkers but Not in Frequent Drinkers. 血清γ-谷氨酰转移酶水平与不常饮酒者高血压的发生有关，而与常饮酒者无关。

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-15 Epub Date: 2025-04-12 DOI: 10.2169/internalmedicine.5129-24

Kazuma Mori, Marenao Tanaka, Tatsuya Sato, Yukinori Akiyama, Hirofumi Ohnishi, Nagisa Hanawa, Masato Furuhashi

{"title":"The Serum γ-Glutamyltransferase Level Is Associated with the Development of Hypertension in Alcohol Infrequent Drinkers but Not in Frequent Drinkers.","authors":"Kazuma Mori, Marenao Tanaka, Tatsuya Sato, Yukinori Akiyama, Hirofumi Ohnishi, Nagisa Hanawa, Masato Furuhashi","doi":"10.2169/internalmedicine.5129-24","DOIUrl":"10.2169/internalmedicine.5129-24","url":null,"abstract":"Objective The controversy persists regarding whether the serum level of γ-glutamyltransferase (GGT), a marker of liver damage, is associated with hypertension irrespective of alcohol intake. Methods We investigated the relationship between the GGT level and new-onset hypertension during a 10-year follow-up period in Japanese individuals who underwent annual health examinations (n=28,990). After excluding subjects without systolic blood pressure and GGT data and those with hypertension at baseline, a total of 18,618 subjects (men/women: 11,262/7,356, mean age: 44 years) were enrolled. Results During the follow-up period, 2,753 men (24.4%) and 837 women (11.4%) developed hypertension. When the subjects were divided by quartiles of GGT at baseline (Q1-Q4), multivariable Cox proportional hazard model analyses after adjustment for age, sex, systolic blood pressure, body mass index, levels of uric acid, estimated glomerular filtration rate, family history of hypertension, habits of current smoking and alcohol drinking, and diagnosis of diabetes mellitus and dyslipidemia showed that hazard ratios (HRs) for the development of hypertension were significantly higher in the Q2, Q3, and Q4 groups than in the Q1 group. A significant interaction was observed between alcohol drinking habits and the GGT level at baseline for the development of hypertension (p=0.022), and adjusted HRs were similarly significant in alcohol infrequent drinkers (≤5 days/week). However, the GGT level was not significantly associated with the development of hypertension in frequent alcohol drinkers (≥6 days/week). Conclusion A high GGT level is an independent predictor of new-onset hypertension in infrequent alcohol drinkers but not in frequent drinkers.","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"2934-2943"},"PeriodicalIF":1.1,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143994132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Systemic Review and Meta-analysis of the Incidence Rate of Interstitial Lung Disease in Patients with Unresectable Pancreatic Cancer Treated with Gemcitabine and Nab-paclitaxel Combination Therapy in the Japanese Population. 日本人群中接受吉西他滨和nab -紫杉醇联合治疗的不可切除胰腺癌患者间质性肺病发病率的系统评价和荟萃分析

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-15 Epub Date: 2025-04-12 DOI: 10.2169/internalmedicine.5084-24

Rei Ohira, Rei Suzuki, Hiroyuki Asama, Mitsuru Sugimoto, Kentaro Sato, Hiroshi Shimizu, Tadayuki Takagi, Takuto Hikichi, Jun Nakamura, Tsunetaka Kato, Takumi Yanagita, Hiromasa Ohira

{"title":"A Systemic Review and Meta-analysis of the Incidence Rate of Interstitial Lung Disease in Patients with Unresectable Pancreatic Cancer Treated with Gemcitabine and Nab-paclitaxel Combination Therapy in the Japanese Population.","authors":"Rei Ohira, Rei Suzuki, Hiroyuki Asama, Mitsuru Sugimoto, Kentaro Sato, Hiroshi Shimizu, Tadayuki Takagi, Takuto Hikichi, Jun Nakamura, Tsunetaka Kato, Takumi Yanagita, Hiromasa Ohira","doi":"10.2169/internalmedicine.5084-24","DOIUrl":"10.2169/internalmedicine.5084-24","url":null,"abstract":"Objective Drug-induced interstitial lung disease (DI-ILD) is an adverse effect of the combination of gemcitabine and nab-paclitaxel (GnP) treatment that has raised concerns because the incidence rate of DI-ILD in the real world is higher than that reported in initial clinical trials. The present study assessed the cumulative incidence rate of DI-ILD among patients treated with GnP based on previously published studies and explored any potential bias in the results. Methods We conducted a meta-analysis in accordance with the Preferred Reporting Items for Systematic reviews and Meta-Analysis guidelines. The MEDLINE, Scopus, and Cochrane Library databases were searched from 2013 to 2024, using specific keywords. Randomized controlled trials, prospective studies, retrospective studies, and case-control studies that reported the incidence of interstitial lung disease (ILD) among patients treated with GnP were included. Two reviewers independently extracted the data from the included studies. Results Nine studies involving 1,980 patients were included in this analysis. Nine studies were conducted in Japan. The pooled incidence of DI-ILD was 5.9%. A subgroup analysis revealed that smaller studies reported higher incidence rates (≤200 vs. ≥201 cases: 9.4% vs. 4.1%). There was significant heterogeneity and publication bias, suggesting that the variability in incidence rates was due to the study size and potential biases. Conclusion The pooled incidence of ILD among patients treated with GnP was 5.9%. However, the results should be interpreted with caution because of the heterogeneity and publication bias. Further global studies are required to determine the true incidence of ILD.","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"2928-2933"},"PeriodicalIF":1.1,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Budd-Chiari Syndrome after Living Liver Donor Hepatectomy. 活体肝供肝切除术后的Budd-Chiari综合征。

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-01 Epub Date: 2025-03-08 DOI: 10.2169/internalmedicine.4995-24

Takahiko Omameuda, Yasuharu Onishi, Yasunaru Sakuma

引用次数: 0

The Presence of Mollaret Cells in Recurrent Meningitis. Mollaret细胞在复发性脑膜炎中的存在。

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-01 Epub Date: 2025-04-12 DOI: 10.2169/internalmedicine.4780-24

Aoi Umino, Toshihiro Ide, Keisuke Tsumura, Haruki Koike

引用次数: 0

Investigation of the Number of Oral Bacteria in Patients with Chronic Obstructive Pulmonary Disease, Asthma, and Asthma and Chronic Obstructive Pulmonary Disease Overlap. 慢性阻塞性肺疾病、哮喘及哮喘与慢性阻塞性肺疾病重叠患者口腔细菌数量调查

IF 1.1 4区医学

Internal Medicine Pub Date : 2025-10-01 Epub Date: 2025-03-22 DOI: 10.2169/internalmedicine.4825-24

Toshiya Inui, Maya Tsuchiya, Takayasu Watanabe, Mitsuru Sada, Atsuto Mouri, Shinkichi Iwanari, Mitsuhiro Kamimura

{"title":"Investigation of the Number of Oral Bacteria in Patients with Chronic Obstructive Pulmonary Disease, Asthma, and Asthma and Chronic Obstructive Pulmonary Disease Overlap.","authors":"Toshiya Inui, Maya Tsuchiya, Takayasu Watanabe, Mitsuru Sada, Atsuto Mouri, Shinkichi Iwanari, Mitsuhiro Kamimura","doi":"10.2169/internalmedicine.4825-24","DOIUrl":"10.2169/internalmedicine.4825-24","url":null,"abstract":"Objective Bacteria in the airways are reportedly involved in the pathogenesis of chronic obstructive pulmonary disease (COPD) and asthma. In addition, oral bacteria are thought to contribute to respiratory diseases by migrating to the airway. Therefore, we investigated whether or not the number of oral bacteria influences COPD, asthma, and asthma and COPD overlap (ACO). Methods We analyzed the correlations between the number of oral bacteria and clinical variables, such as pulmonary function tests, in patients with COPD, asthma, and ACO whose condition was stable and who visited our center from August 2019 to December 2020. The number of oral bacteria was assessed using the dielectrophoretic impedance measurement method. Results In patients with COPD (n=50), the number of oral bacteria was significantly negatively correlated with the percentage predicted forced expiratory volume in one second (%FEV1), percentage peak expiratory flow, and percentage forced vital capacity but was not correlated with the COPD Assessment Test. In patients with asthma (n=32), it was significantly negatively correlated with the FEV1 percentage and with the increase in FEV1 in the reversibility test but not with fractional exhaled nitric oxide. In patients with ACO (n=39), we found no significant correlation between the number of oral bacteria and any clinical variable. Conclusion The results suggest that the number of oral bacteria is associated with both lung capacity and airflow obstruction in patients with COPD and with airflow obstruction in patients with asthma.","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"2829-2838"},"PeriodicalIF":1.1,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12549041/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0