Internal Medicine最新文献_第3页

Widespread Muscle Calcification due to Neuroleptic Malignant Syndrome. 神经性恶性综合征引起的广泛肌肉钙化。

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-09-04 DOI: 10.2169/internalmedicine.4148-24

Naoyoshi Yoneyama, Shoichiro Hamada, Taro Shimono, Mikio Nakajima

引用次数: 0

Association between the Cardiothoracic Ratio on Chest X-rays and the Respiratory Function in Patients with Interstitial Lung Diseases: a Cross-sectional Study. 间质性肺病患者胸部 X 射线上的心胸比例与呼吸功能之间的关系：一项横断面研究。

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-08-28 DOI: 10.2169/internalmedicine.4104-24

Akihiko Hagiwara, Izumi Yamatani, Ryohei Kudoh, Kazufumi Hiramatsu, Jun-Ichi Kadota, Kosaku Komiya

{"title":"Association between the Cardiothoracic Ratio on Chest X-rays and the Respiratory Function in Patients with Interstitial Lung Diseases: a Cross-sectional Study.","authors":"Akihiko Hagiwara, Izumi Yamatani, Ryohei Kudoh, Kazufumi Hiramatsu, Jun-Ichi Kadota, Kosaku Komiya","doi":"10.2169/internalmedicine.4104-24","DOIUrl":"10.2169/internalmedicine.4104-24","url":null,"abstract":"Objective Patients with advanced interstitial lung disease (ILD) struggle to undergo spirometry to evaluate the respiratory function. The cardiothoracic ratio (CTR) on chest radiography can potentially reflect the lung volume; however, this has not yet been fully established. This study aimed to clarify the relationship between the CTR and the respiratory function in patients with interstitial lung diseases. Methods We reviewed 120 consecutive patients with idiopathic interstitial lung disease who were admitted to our department between April 2018 and March 2023 and who underwent chest radiography, spirometry, and echocardiography. A multiple linear regression analysis was used to identify the factors associated with the CTR. Correlations between the CTR and the respiratory or cardiac function were assessed using Pearson's correlation coefficient. Results A multiple linear regression analysis showed the percent vital capacity (β= -0.598, p<0.001), age (β=0.405, p<0.001), and female sex (β=0.177, p=0.047) to be independently associated with the CTR, whereas no relationship was observed between the left ventricular ejection fraction, body mass index, and smoking habits. The CTR was significantly negatively correlated with the vital capacity (r=-0.490, p<0.001). Conclusion An increased CTR might reflect a decreased vital capacity, but not a decreased cardiac function, in patients with interstitial lung diseases. Measuring the CTR can thus be beneficial for predicting progression in patients with ILD.","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"1025-1030"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142092839","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Determinants of In-hospital Death in Non-ST-segment Elevation Myocardial Infarction with Triple-vessel Disease. 非 ST 段抬高心肌梗死伴三血管疾病患者院内死亡的决定因素

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-09-04 DOI: 10.2169/internalmedicine.3949-24

Yuki Tokunaga, Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Kei Yamamoto, Takunori Tsukui, Masashi Hatori, Taku Kasahara, Shun Ishibashi, Yusuke Watanabe, Masaru Seguchi, Hideo Fujita

{"title":"Determinants of In-hospital Death in Non-ST-segment Elevation Myocardial Infarction with Triple-vessel Disease.","authors":"Yuki Tokunaga, Kenichi Sakakura, Hiroyuki Jinnouchi, Yousuke Taniguchi, Kei Yamamoto, Takunori Tsukui, Masashi Hatori, Taku Kasahara, Shun Ishibashi, Yusuke Watanabe, Masaru Seguchi, Hideo Fujita","doi":"10.2169/internalmedicine.3949-24","DOIUrl":"10.2169/internalmedicine.3949-24","url":null,"abstract":"Objective Triple-vessel disease (TVD) is a well-established prognostic factor for patients with acute myocardial infarction. However, there is a paucity of literature regarding the risk factors for in-hospital death in patients with non-ST-segment elevation myocardial infarction (NSTEMI) and TVD. In this retrospective study, we examined the determinants of in-hospital death in patients with NSTEMI and TVD who underwent percutaneous coronary intervention (PCI) for culprit lesions. Methods The primary objective of this study was to identify the factors associated with in-hospital death using a multivariate analysis. We included 253 patients with NSTEMI and TVD and divided them into a survivor group (n=239) and an in-hospital death group (n=14). Results Systolic blood pressure (SBP) at admission was significantly higher in the survivor group than in the in-hospital death group. The estimated glomerular filtration rate (eGFR) was also higher in the survivor group than in the in-hospital death group. In the multivariate logistic regression analysis, in-hospital death was inversely associated with the SBP at admission [odds ratio (OR) 0.984, 95% confidence interval (CI) 0.970-0.999, p<0.035] and eGFR (OR 0.966, 95% CI 0.939-0.994, p=0.019) and was associated with cardiopulmonary arrest (CPA) before PCI (OR 8.448, 95% CI 1.863-38.309, p=0.006). Conclusion In-hospital death was associated with CPA before PCI and inversely associated with the SBP at admission and eGFR in patients with NSTEMI and TVD who underwent PCI for the culprit lesion. It may be important to recognize these high-risk features in order to improve the clinical outcomes of patients with NSTEMI and TVD.","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"993-999"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Long-term Major Adverse Cardiac Event Prediction by Computed Tomography-derived Plaque Measures and Clinical Parameters Using Machine Learning. 利用机器学习通过计算机断层扫描衍生斑块测量和临床参数预测长期重大心脏不良事件。

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-09-04 DOI: 10.2169/internalmedicine.3566-24

Shinichi Wada, Makino Sakuraba, Michikazu Nakai, Takayuki Suzuki, Yoshihiro Miyamoto, Teruo Noguchi, Yoshitaka Iwanaga

{"title":"Long-term Major Adverse Cardiac Event Prediction by Computed Tomography-derived Plaque Measures and Clinical Parameters Using Machine Learning.","authors":"Shinichi Wada, Makino Sakuraba, Michikazu Nakai, Takayuki Suzuki, Yoshihiro Miyamoto, Teruo Noguchi, Yoshitaka Iwanaga","doi":"10.2169/internalmedicine.3566-24","DOIUrl":"10.2169/internalmedicine.3566-24","url":null,"abstract":"Objective The present study evaluated the usefulness of machine learning (ML) models with the coronary computed tomography imaging and clinical parameters for predicting major adverse cardiac events (MACEs). Methods The Nationwide Gender-specific Atherosclerosis Determinants Estimation and Ischemic Cardiovascular Disease Prospective Cohort study (NADESICO) of 1,187 patients with suspected coronary artery disease 50-74 years old was used to build a MACE prediction model. The ML random forest (RF) model was compared with a logistic regression analysis. The performance of the ML model was evaluated using the area under the curve (AUC) with the 95% confidence interval (CI). Results Among 1,178 patients from the NADESICO dataset, MACEs occurred in 103 (8.7%) patients during a median follow-up of 4.4 years. The AUC of the RF model for MACE prediction was 0.781 (95% CI: 0.670-0.870), which was significantly higher than that of the conventional logistic regression model [AUC, 0.750 (95% CI: 0.651-0.839)]. The important features in the RF model were coronary artery stenosis (CAS) at any site, CAS in the left anterior descending branch, HbA1c level, CAS in the right coronary artery, and sex. In the external validation cohort, the model accuracy of ensemble ML-RF models that were trained on and tuned using the NADESICO dataset was not similar [AUC: 0.635 (95% CI: 0.599-0.672)]. Conclusion The ML-RF model improved the long-term prediction of MACEs compared to the logistic regression model. However, the selected variables in the internal dataset were not highly predictive of the external dataset. Further investigations are required to validate the usefulness of this model.","PeriodicalId":13719,"journal":{"name":"Internal Medicine","volume":" ","pages":"1001-1008"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142132663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Pharyngeal Papillary Lesion of Syphilis. 梅毒的咽乳头病变

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-08-28 DOI: 10.2169/internalmedicine.4352-24

Hidenori Nakagawa, Atsushi Hanamoto, Miho Sakaida, Michinori Shirano

引用次数: 0

First Reported Case of Pure Red Cell Aplasia Related to Sotorasib. 首例报告的与索托拉西布有关的纯红细胞增生症病例

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-09-04 DOI: 10.2169/internalmedicine.3961-24

Katsuhiro Itogawa, Tatsuya Saito, Yuya Nakata, Hikari Amari, Hiroki Tahara, Nozomu Yoshino, Yuki Maeda, Motoko Nomura, Jun Shiihara, Yoshiaki Nagai, Hiromitsu Ohta, Yasuhiro Yamaguchi

引用次数: 0

Transient Poor R-wave Progression Associated with Asymptomatic Pneumothorax. 与无症状气胸相关的一过性 R 波进展不佳。

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-08-28 DOI: 10.2169/internalmedicine.4062-24

Shimpei Watanabe, Masahiro Ito

引用次数: 0

Three Cases of Subdural Hematoma with Transient Neurological Deficits: Importance of Sulcal Hyperintensity in Magnetic Resonance Imaging Fluid-attenuated Inversion Recovery Images. 硬膜下血肿伴短暂神经功能缺损的三例病例：磁共振成像流体减弱反转恢复图像中颅底高密度的重要性。

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-09-04 DOI: 10.2169/internalmedicine.4001-24

Nobutaka Takahashi, Takayasu Mishima, Daito Nakamura, Shinsuke Fujioka, Yoshio Tsuboi

引用次数: 0

Pulmonary Manifestations of Chlorine Gas Poisoning. 氯气中毒的肺部表现。

IF 1 4区医学

Internal Medicine Pub Date : 2025-04-01 Epub Date: 2024-09-04 DOI: 10.2169/internalmedicine.4202-24

Masahiro Kashiura, Hiroyuki Tamura, Takashi Moriya

引用次数: 0

Disseminated Nocardiosis in Idiopathic CD4 Lymphocytopenia: A Rare Case and Literature Review.

IF 1 4区医学

Internal Medicine Pub Date : 2025-03-29 DOI: 10.2169/internalmedicine.4984-24

Nayuta Seto, Takayuki Suzuki, Takahiko Fukuchi, Momori Honjo, Shinya Watanabe, Longzhu Cui, Hitoshi Sugawara

引用次数: 0