良性疾病放疗后28年胸腔内放射诱发的骨肉瘤：一个尸检病例。

IF 1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-04-12 DOI:10.2169/internalmedicine.5162-24

Shima Sunanaga, Yusuke Sunanaga, Hirotaka Uto, Jiro Nakashioya, Takafumi Hamada, Yusuke Fujino, Shuya Tanaka

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引用次数: 0

摘要

一位60岁男性，28年前因良性疾病（动脉瘤性骨囊肿）接受放射治疗，因呼吸困难和吞咽困难入院。计算机断层扫描显示一个8厘米的肿瘤侵入气管和食道。他的病情迅速恶化，并于住院第27天死亡。尸检显示为放射性骨肉瘤。良性疾病在放射治疗后也可发生放射诱导肉瘤，这种情况下潜伏期可能更长。此外，预后取决于可切除肿瘤的位置。因此，良性疾病放疗后应进行较长期的内部影像学随访，以发现早期肉瘤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Radiation-induced Osteosarcoma in the Thoracic Cavity 28 Years after Irradiation for a Benign Disease: An Autopsy Case.

A 60-year-old man with a history of radiation therapy 28 years ago for a benign disease (an aneurysmal bone cyst) was admitted with dyspnea and dysphagia. Computed tomography showed an 8-cm tumor invading the trachea and esophagus. His condition declined rapidly, and he died on day 27 of hospitalization. Autopsy revealed radiation-induced osteosarcoma. Radiation-induced sarcoma can develop even after radiotherapy for benign diseases, in which case the latency period might be longer. Furthermore, the prognosis depends on the location of the resectable tumor. Therefore, longer-term internal imaging follow-up should be performed after radiotherapy for benign diseases to detect early-stage sarcoma.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.