Health physics最新文献_第7页

Lutetium-177 Therapy in Italy: Environmental Impact Assessment in Anticipation of Its Widespread Use in Prostate Cancer Treatment. 意大利的镥 177 治疗：前列腺癌治疗广泛使用前的环境影响评估。

IF 1 4区医学

Health physics Pub Date : 2025-04-01 Epub Date: 2024-09-27 DOI: 10.1097/HP.0000000000001893

Anna Brusa, Fabrizio Campi, Claudia Cavatorta, Alessandro Antonio Porta, Sofia Viganò

{"title":"Lutetium-177 Therapy in Italy: Environmental Impact Assessment in Anticipation of Its Widespread Use in Prostate Cancer Treatment.","authors":"Anna Brusa, Fabrizio Campi, Claudia Cavatorta, Alessandro Antonio Porta, Sofia Viganò","doi":"10.1097/HP.0000000000001893","DOIUrl":"10.1097/HP.0000000000001893","url":null,"abstract":"Abstract: This article addresses the evolving state of lutetium-177 radiopharmaceutical therapies in Italy, focusing on the importance of the definition of patient management practices regarding the approved treatments based on [ 177 Lu]Lu-DOTATATE for neuroendocrine tumors and [ 177 Lu]Lu-PSMA-617 for metastatic castration-resistant prostate cancer. Italian medical facilities are facing new challenges with the increase in the demand for such therapies while transitioning from restrictive hospitalization requirements to more flexible outpatient options. Therefore, four management strategies are described here, varying from immediate discharge after the administration to 24-h hospitalization, and their environmental and radiation safety implications are evaluated through simple models aimed at assessing the effective doses on the local population and wastewater purification plant workers. Results show that, while higher effective doses may be caused by an immediate discharge-based modality, they remain within acceptable limits, particularly when dealing with a smaller number of patients. Prolonged hospitalizations guarantee superior radiation safety levels but might not be sustainable with the expected increase in patient volumes in the future.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":"286-290"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142345586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protecting Our Own: A Method for Reducing Breast Radiation Exposure in Healthcare Workers. 保护我们自己：减少医护人员乳房辐射暴露的方法》（Protecting Our Own: A Method for Reducing Breast Radiation Exposure in Healthcare Workers）。

IF 1 4区医学

Health physics Pub Date : 2025-04-01 Epub Date: 2024-05-06 DOI: 10.1097/HP.0000000000001832

Lauren Zammerilla Westcott, Gerald O Ogola, Chet R Rees

{"title":"Protecting Our Own: A Method for Reducing Breast Radiation Exposure in Healthcare Workers.","authors":"Lauren Zammerilla Westcott, Gerald O Ogola, Chet R Rees","doi":"10.1097/HP.0000000000001832","DOIUrl":"10.1097/HP.0000000000001832","url":null,"abstract":"Abstract: Standard lead aprons do not protect the female breast adequately from radiation exposure, which has been associated with breast cancer in healthcare workers. A novel lead shield was designed to reduce radiation to the breast, axilla, and thyroid (BAT). A procedure room was simulated with an anthropomorphic phantom representing the operator. Dosimeters were positioned on the outer quadrant of each breast, the chest, the thyroid, and deep inside of a phantom acrylic female torso with neck and head. Standard lead vest plus a thyroid shield was used as control and compared to standard lead vest plus BAT shield. Three operator and two image receptor positions were tested. The reductions in radiation exposure were calculated. The standard vest plus BAT shield provided significant reductions in radiation exposure for all anatomic locations compared to control. When averaging all operator positions, the BAT provided reductions of 91% (p < 0.0001) for near breast. Reductions for far breast, chest, thyroid, and deep tissues were 76% (p = 0.016), 94% (p < 0.0001), 52% (p = 0.026), and 60% (p = 0.004). With operator 90° to the table using a cross-table lateral beam, the BAT provided a 97.7% reduction in radiation to the near breast and significant reduction in radiation to the chest, thyroid, and deep tissues. The BAT shield reduces radiation exposure to the breast, chest, thyroid and deep hematopoietic tissues. Such shields could benefit healthcare workers to reduce the risk of breast cancer and other radiation-associated cancers.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":"267-272"},"PeriodicalIF":1.0,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140860039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Natural Radioactivity in Drinking Water Sourced from Groundwater in Central and Northern Queensland. 昆士兰中部和北部地下水饮用水中的天然放射性。

IF 1 4区医学

Health physics Pub Date : 2025-03-31 DOI: 10.1097/HP.0000000000001970

Peter Medley, Matthew Wiggins, Michelle Thomas, Sarah Mullins, Pierre Bouchereau-de Pury

{"title":"Natural Radioactivity in Drinking Water Sourced from Groundwater in Central and Northern Queensland.","authors":"Peter Medley, Matthew Wiggins, Michelle Thomas, Sarah Mullins, Pierre Bouchereau-de Pury","doi":"10.1097/HP.0000000000001970","DOIUrl":"https://doi.org/10.1097/HP.0000000000001970","url":null,"abstract":"Determination of 210Pb, 210Po, 234U, and 238U activity concentrations in groundwater sources used for drinking water can improve confidence in ingestion dose assessments used for comparison with radiological governance guidelines, such as the Australian Drinking Water Guidelines. Such results can provide additional guidance information for detailed assessments where water supplies exhibit high relative concentrations of natural radioactivity. Measurements of these radionuclides, as well as the more commonly measured gross alpha and beta, 226Ra, and 228Ra activity concentrations, were undertaken for 21 water supplies in regional Queensland, Australia. Groundwater was the primary or only source for these water supplies. Dose assessment using the measured values based on the Australian Drinking Water Guidelines assumed water consumption, and estimates of actual consumption rates in the Australian population were undertaken for different age groups. The validity of assumptions underpinning screening assessments based on gross alpha and gross beta activity results and measurement of 226Ra and 228Ra were shown to be valid. The adolescent age group (14-18 y) was identified as a potential critical group for dose assessment where activity concentrations of 226Ra and 228Ra were elevated. Other radionuclides, 210Pb, 210Po, 234U, and 238U were shown to be significant contributors to overall committed effective dose in several water supplies; however, total doses in those supplies were well below the operational dose value of 0.3 mSv from the Australian Drinking Water Guidelines. Improved detection limits for 228Ra could improve accuracy of dose assessments from drinking water.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Assessing the Excess Lifetime Cancer Risk from Water in the Euphrates River, Najaf, Iraq. 评估伊拉克纳杰夫幼发拉底河中过量的终身癌症风险。

IF 1 4区医学

Health physics Pub Date : 2025-03-26 DOI: 10.1097/HP.0000000000001959

Ali Yahya Salman, Shaymaa Awad Kadhim, Hussain M Hussain, Fadhil I Sharrad

{"title":"Assessing the Excess Lifetime Cancer Risk from Water in the Euphrates River, Najaf, Iraq.","authors":"Ali Yahya Salman, Shaymaa Awad Kadhim, Hussain M Hussain, Fadhil I Sharrad","doi":"10.1097/HP.0000000000001959","DOIUrl":"https://doi.org/10.1097/HP.0000000000001959","url":null,"abstract":"Abstract: Water is the basic element for the continuation of human life for all inhabitants, animals and plants on Earth, and water cannot be dispensed with as it is a basis of life. This study focuses on measuring radiation to assess activity levels of some radionuclides in the waters of the Euphrates River, which is the main tributary of drinking water in Najaf, Iraq, and determining whether it is safe for health in terms of radiation. The concentrations of three gamma-emitting nuclides (226Ra, 232Th, and 40K) were measured in a section of the Euphrates River using gamma-ray spectroscopy using a 3\" × 3\" sodium iodide scintillation detector doped with thallium and connected to software version MAESTRO-32. Twenty-nine water samples were collected at regular intervals along the Euphrates River within the administrative boundaries of Al-Najaf Al-Ashraf Governorate. The Al-Mishkab branch results showed activity concentration levels of 226Ra, 232Th, and 40K that are 3.182 ± 1.514, 1.572 ± 0.509, and 26.715 ± 17.082 Bq L-1, respectively. For Al-Qadesia branch, the activity concentrations are equal to 3.190 ± 1.350, 2.190 ± 1.082, and 37.135 ± 29.464 Bq L-1, respectively, which is within the maximum acceptable concentration levels recommended by the World Health Organization. The annual effective ingestion dose (EID) due to the specific activities of the three nuclides is equal to 0.311 ± 0.103 and 0.357 ± 0.144 mSv y-1 for the Al-Mishkab branch and the Al-Qadesia branch, respectively. The excess lifetime cancer risk (ELCR) values are 1.197 ± 0.395 and 1.373 ± 0.553 × 10-3 for the Al-Mishkab and Al-Qadesia branches, respectively. Therefore, the study concluded that radiation levels in the river water are a significant risk to public health because the concentrations of the studied nuclides are higher than what is globally permitted according to the U.S. Environmental Protection Agency.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143709717","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unusual Encounters in Medical Health Physics and Nuclear Medicine: Learning From the Unexpected. 医学、健康物理和核医学中的不寻常遭遇：从意外中学习。

IF 1 4区医学

Health physics Pub Date : 2025-03-24 DOI: 10.1097/HP.0000000000001974

Kimyli Lemieux, Bryan Lemieux, Olwen Burton, M Elizabeth Oates, Xingyu Nie, Georgette Lauersdorf, Riham El Khouli, Elizabeth Cheatham, Blaine Mischen, Jie Zhang

{"title":"Unusual Encounters in Medical Health Physics and Nuclear Medicine: Learning From the Unexpected.","authors":"Kimyli Lemieux, Bryan Lemieux, Olwen Burton, M Elizabeth Oates, Xingyu Nie, Georgette Lauersdorf, Riham El Khouli, Elizabeth Cheatham, Blaine Mischen, Jie Zhang","doi":"10.1097/HP.0000000000001974","DOIUrl":"https://doi.org/10.1097/HP.0000000000001974","url":null,"abstract":"Abstract: This paper presents six case studies highlighting real-world incidents in nuclear medicine, focusing on issues such as radioactive contamination, equipment malfunctions, and safety risks. These cases illustrate the challenges faced in maintaining patient and staff safety during complex procedures, underscoring the importance of rapid response and clear communication among healthcare teams. Each case reveals the need for effective contamination control strategies, robust safety protocols, and staff preparedness to handle unexpected situations. The responses to these incidents emphasize the value of continuous staff training and adherence to best practices to minimize risks. This paper also discusses the importance of process improvements and protocol refinements, particularly in managing contamination, ensuring compliance with regulatory standards, and maintaining clinical operations. Lessons learned from these cases offer practical guidance for enhancing contamination control measures, optimizing safety practices, and reducing disruptions to treatment workflows. Finally, this paper emphasizes the importance of preparedness, adaptability, and continuous learning in maintaining a high standard of safety in nuclear medicine.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on MicroRNAs as Potential Biomarkers of Radon-induced Radiation Damage. 微rna作为氡致辐射损伤潜在生物标志物的研究。

IF 1 4区医学

Health physics Pub Date : 2025-03-19 DOI: 10.1097/HP.0000000000001969

Lu Sun, Na Wang, Jianlei Ruan, Gang Gao, Yan Pan, Chunnan Piao, Huanhuan Li, Sitong Liu, Zhuo Zhang, Yong Cui, Sumei Sun, Jianxiang Liu

{"title":"Study on MicroRNAs as Potential Biomarkers of Radon-induced Radiation Damage.","authors":"Lu Sun, Na Wang, Jianlei Ruan, Gang Gao, Yan Pan, Chunnan Piao, Huanhuan Li, Sitong Liu, Zhuo Zhang, Yong Cui, Sumei Sun, Jianxiang Liu","doi":"10.1097/HP.0000000000001969","DOIUrl":"https://doi.org/10.1097/HP.0000000000001969","url":null,"abstract":"Abstract: High concentrations of radon may cause radiation damage to the human body. Finding the biomarkers of radon-induced radiation damage is particularly important for the research and treatment of radon-induced lung cancer. In this study, the expression of γH2AX protein in peripheral blood lymphocytes of miners exposed to high concentrations of radon was detected by flow cytometry. To investigate the possible damage in peripheral blood lymphocytes of miners under a high radon environment, a microRNA (miRNA) microarray technique was used to screen the differentially expressed miRNAs in the peripheral plasma of miners exposed to different concentrations of radon. Prediction of the target genes and the possible biological functions of differentially expressed miRNAs in the peripheral plasma of miners was performed. The results indicated that the relative expression level of γH2AX protein in peripheral blood lymphocytes of miners was significantly higher than that of the control group (P < 0.05). Bioinformatics methods were used to predict the differential expression miRNA chip to screen the target genes of differentially expressed miRNAs and the signaling pathways that may be involved in screening differentially expressed miRNA target genes and to investigate the relationship between some different miRNA target genes and cellular pathways. The analysis of the cellular pathways predicted by differentially expressed miRNAs, including the process of cell cycle, provides new information for the study of miRNAs as potential biomarkers of radon-induced radiation damage in peripheral blood.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preliminary Study of Dose Rates to Rhinoceros Basal Cells from a Radioactive Source to Deter Poaching. 放射源对犀牛基底细胞剂量率抑制偷猎的初步研究。

IF 1 4区医学

Health physics Pub Date : 2025-03-19 DOI: 10.1097/HP.0000000000001953

Jordan A Hillis, Craig M Marianno, Thomas E Johnson, James Larkin

{"title":"Preliminary Study of Dose Rates to Rhinoceros Basal Cells from a Radioactive Source to Deter Poaching.","authors":"Jordan A Hillis, Craig M Marianno, Thomas E Johnson, James Larkin","doi":"10.1097/HP.0000000000001953","DOIUrl":"https://doi.org/10.1097/HP.0000000000001953","url":null,"abstract":"Abstract: The five populations of rhinoceros species have declined in the wild due to poaching and habitat degradation, with demand for rhinoceros horn driving the poaching industry. The poaching of rhinoceros horn has critically threatened the conservation status of over half of these animals in the world today. To combat this threat and safeguard the species, a method involving the insertion of a radiation source into the rhinoceros's horn has been proposed. This approach aims to deter poachers due to public fear of radiation and enable the detection of smuggled horns based on the source's radioactive properties. To determine the health risks to the rhinoceros, this study presents the dose rate response functions to the rhino's epithelial basal stem cells that form the horn. The assessed responses assumed a modeled source centered at 10 and 20 cm above the basal stem cells. To identify the most appropriate source, dose rates were produced from gamma sources ranging from 0.1 to 2 MeV. Using numerical calculations, conservative dose rate estimates were determined as a function of energy and normalized to source activity, providing a foundation for computational results using Monte Carlo N-Particle Code version 6.2. With the dose rate responses as a function of energy and activity, the risk of deterministic and stochastic effects in this most at-risk tissue were understood based on the skin dose limitations for preventing deterministic effects to the rhinoceros.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Toward a Scheme for Evaluating the Performance of Continuous Particulate Air Monitor Quantitative Methods. 连续颗粒物空气监测定量方法性能评价方案的探讨。

IF 1 4区医学

Health physics Pub Date : 2025-03-14 DOI: 10.1097/HP.0000000000001966

William Evans

引用次数: 0

The Effect of X-ray Security Imaging on Optically Stimulated Luminescence Personnel Dosimetry. x射线安全成像对光激发发光人体剂量学的影响。

IF 1 4区医学

Health physics Pub Date : 2025-03-14 DOI: 10.1097/HP.0000000000001958

Derek Lewis, Connor Williams, Seth Kanter

{"title":"The Effect of X-ray Security Imaging on Optically Stimulated Luminescence Personnel Dosimetry.","authors":"Derek Lewis, Connor Williams, Seth Kanter","doi":"10.1097/HP.0000000000001958","DOIUrl":"https://doi.org/10.1097/HP.0000000000001958","url":null,"abstract":"Abstract: Federal regulations mandate that all radiological workers in the United States, as well as those individuals who may receive non-trivial occupational doses of radiation, must have their external radiation doses monitored and tracked as accurately as possible. Typically, this is done through the use of personnel dosimetry devices, such as optically stimulated luminescence (OSL) dosimeters, which are worn on the body and keep an accurate record of the radiation to which a person has been exposed over a period of time. Unfortunately, the inadvertent passage of OSL dosimeters through airport x-ray security scanners can compromise the accuracy of this running dose record and therefore impede the ability for employers to accurately report work-related doses. With the advent of advanced resolution security technology used in many airports, this once relatively minor issue now requires that the Idaho National Laboratory (INL) Radiological Controls organization be able to accurately discern non-occupational doses received in this way. This research will discuss the methods and models for adjusting dose readings for Landauer InLight Model 2 OSL personnel dosimeters used at the INL that have been subjected to three types of x-ray scans commonly used at airport checkpoints, and the implications of these data across the rest of the US DOE complex.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":" ","pages":""},"PeriodicalIF":1.0,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143630351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Review of CRCPD Efforts in the Disposition of Disused Radioactive Sources. CRCPD在废弃放射源处置方面的工作综述。

IF 1 4区医学

Health physics Pub Date : 2025-03-01 DOI: 10.1097/HP.0000000000001870

Ruth E McBurney, Kimberly Steves

{"title":"Comprehensive Review of CRCPD Efforts in the Disposition of Disused Radioactive Sources.","authors":"Ruth E McBurney, Kimberly Steves","doi":"10.1097/HP.0000000000001870","DOIUrl":"10.1097/HP.0000000000001870","url":null,"abstract":"Abstract: The Conference of Radiation Control Program Directors (CRCPD), a national non-profit, non-governmental organization dedicated to radiation protection, established a National Radioactive Material Disposition Program to assist state radiation control programs, licensees, and members of the public in managing orphan sources and otherwise unwanted or disused radioactive material. The program consists of several services including technical assistance with disposition options; financial assistance to radiation control programs for the disposition of orphan sources; and the Source Collection and Threat Reduction (SCATR) Program for financial and logistical assistance in the disposal of unwanted sources. For the past 18 years, the CRCPD has partnered with the Department of Energy's National Nuclear Security Administration (NNSA) to provide outreach to licensees and assistance in the disposal of disused sources, through the SCATR Program. The overarching goal of the SCATR Program is to design and execute a comprehensive and cost-effective process for identifying and reducing the threat of diversion of radioactive material for misuse, focusing on those sources that have a commercial disposal path. During the time the program has been in place, the scope has expanded to include higher activity sources, such as irradiators, and source collections in unusual circumstances. Progress toward the goals, disposal and transportation issues, and ancillary concerns being addressed by CRCPD are discussed.","PeriodicalId":12976,"journal":{"name":"Health physics","volume":"128 3","pages":"233-239"},"PeriodicalIF":1.0,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0