Food Science & Nutrition最新文献_第2页

Biocontrol of Aflatoxigenic Maize Molds Using Lactobacillus spp.-Based Formulations 乳酸菌配方对玉米黄曲霉毒素的生物防治。

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-29 DOI: 10.1002/fsn3.71039

Inoussa Ilboudo, Hamidou Compaoré, Inoussa Compaoré, Sheryl Mounira Traoré, Laeticia Ella Dembélé, Fulbert Nikièma, Lanterbecq Déborah, Hagrétou Sawadogo-Lingani, Elie Kabré

{"title":"Biocontrol of Aflatoxigenic Maize Molds Using Lactobacillus spp.-Based Formulations","authors":"Inoussa Ilboudo, Hamidou Compaoré, Inoussa Compaoré, Sheryl Mounira Traoré, Laeticia Ella Dembélé, Fulbert Nikièma, Lanterbecq Déborah, Hagrétou Sawadogo-Lingani, Elie Kabré","doi":"10.1002/fsn3.71039","DOIUrl":"10.1002/fsn3.71039","url":null,"abstract":"Food contamination by mold is a serious and difficult problem to manage, leading to enormous economic losses. Mycotoxins have been recognized as one of the most dangerous contaminants in food. They can be toxic to humans and animals when they reach a certain ingestion threshold. These mycotoxins include aflatoxins, produced mainly by Aspergillus section Flavi, the most frequently isolated from food being A. flavus and A. parasiticus. Current control methods, mainly physical and chemical, are showing their limitations due to the environmental problems caused, resistance developed by pathogens, and the food organoleptic quality deterioration. Other control alternatives based on biocontrol can be explored. This present study aimed to isolate Lactobacillus spp. from local foods that can inhibit aflatoxigenic molds' growth and reduce aflatoxins production. To this end, four (04) strains (04) collection namely GNc, GNd, F3a, and G3Lab1 from fura and gapal, selected on the basis of their high antifungal potential, were co-cultured with fungi reference strains (UBOCC-A-111042, UBOCC-A-106031, T1, and T2) and on maize aflatoxigenic molds (AF1, AF2, AF3, AP1, and AP2). Bioassays in vitro demonstrated that Lactobacillus spp. strains significantly inhibited fungal radial growth. Further tests were conducted on eleven (11) highly contaminated maize samples, showing a maximum reduction rate of 68% in the fungal flora. Analysis and quantification of residual aflatoxins B1, B2, G1, and G2 in maize grains using liquid chromatography coupled with tandem mass spectrometry (LC–MS/MS) revealed a decrease and, in some cases, complete suppression of aflatoxin B1, B2, G1, and G2 production in grains detoxified with Lactobacillus extracts.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479372/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amyloid Fibrils of Pea Protein Isolated Induced by Cold Plasma Treatment and Its Stabilization on High Internal Phase Emulsions 冷等离子体诱导分离的豌豆蛋白淀粉样原纤维及其在高内相乳剂上的稳定性。

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-29 DOI: 10.1002/fsn3.71038

Jing Wang, Jun-Xiang Liu, Xiu-Bin Liu, Najla AlMasoud, Abderrahmane Aït-Kaddour, Rana Muhammad Aadil, Zhi-Wei Liu

{"title":"Amyloid Fibrils of Pea Protein Isolated Induced by Cold Plasma Treatment and Its Stabilization on High Internal Phase Emulsions","authors":"Jing Wang, Jun-Xiang Liu, Xiu-Bin Liu, Najla AlMasoud, Abderrahmane Aït-Kaddour, Rana Muhammad Aadil, Zhi-Wei Liu","doi":"10.1002/fsn3.71038","DOIUrl":"10.1002/fsn3.71038","url":null,"abstract":"The potential of forming pea protein isolate (PPI) amyloid fibrils promoted by cold plasma (CP) treatment (40 kV; 0, 3, 5, and 7 min), heat treatment (85°C for 12 h), and its ability to stabilize high internal phase emulsions (HIPEs) was investigated. Results indicated that rod-like amyloid fibrils of PPI were successfully formed and promoted by CP treatment, with a 12 nm diameter and 132–261 nm average length, as confirmed by Thioflavin T (ThT) fluorescence spectroscopy, SEM, and TEM. The globular structure unfolding, cleavage of the backbone of PPI by CP treatment, release of the building block “β-strands” structure, and assembly of the building blocks into fibrils during the fibrillation process were confirmed by SDS-PAGE, FTIR, fluorescence spectroscopy, and hydrophobic analysis. Compared with native PPI, fibrous PPI exhibited a strong capacity for stabilizing HIPEs, and the ability to stabilize HIPEs was PPI fibrils length dependent. Compared with HIPEs stabilized by long fibrils (CP5PF-8 and CP5PF-12), the HIPEs prepared by short fibrils (CP5PF-2 and CP5PF-4) displayed better thermal stability. Moreover, CP5PF-stabilized HIPEs exhibited excellent ionic and storage stability, while PPI amyloid fibrils with shorter lengths (CP5PF-2 and CP5PF-4) showed superior performance compared with longer fibrils lengths (CP5PF-8 and CP5PF-12).","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12479367/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Comprehensive Review on Nutritional Traits, Extraction Methods, Oxidative Stability, Encapsulation Technologies, Food Applications and Health Benefits of Omega Fatty Acids 欧米茄脂肪酸的营养特性、提取方法、氧化稳定性、包封技术、食品应用和健康益处综述

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-28 DOI: 10.1002/fsn3.71008

Muhammad Abdul Rahim, Malika Uzma, Fahad Al-Asmari, Hyrije Koraqi, Mohamed Fawzy Ramadan, Roberto Castro-Muñoz, Eliasse Zongo

{"title":"A Comprehensive Review on Nutritional Traits, Extraction Methods, Oxidative Stability, Encapsulation Technologies, Food Applications and Health Benefits of Omega Fatty Acids","authors":"Muhammad Abdul Rahim, Malika Uzma, Fahad Al-Asmari, Hyrije Koraqi, Mohamed Fawzy Ramadan, Roberto Castro-Muñoz, Eliasse Zongo","doi":"10.1002/fsn3.71008","DOIUrl":"10.1002/fsn3.71008","url":null,"abstract":"This review has studied omega fatty acids, their importance, functionality, health benefits, sources, oxidation, preservation, and the function of foods prepared with omega fatty acid edible sources. Omega fatty acids are essential polyunsaturated fatty acids (PUFAs), and their consumption has increased with increasing awareness about their health benefits. Plant oilseeds, including chia seeds (CS), flax seeds, linseeds, sesame seeds, and fish oil (FO), are some of the major sources of omega fatty acids. These essential omega fatty acids have been studied for their health benefits and effectiveness against the pathophysiology of various diseases, including metabolic dysfunction, cardiovascular diseases, malignancy, mental health, neurodegenerative diseases, liver diseases, systemic circulation, and infant mortality. Various in vitro and in vivo studies revealed their effectiveness against these diseases and their complications. Omega fatty acids also reduce the risk of these diseases by improving health and reducing risk factors. Omega fatty acids, being polyunsaturated, are highly susceptible to oxidation, which greatly affects their stability and affects their peroxide value at storage. Various preservation techniques, including traditional encapsulation, microencapsulation, and multilayer encapsulation, are studied and practiced to prevent oxidation. To make omega fatty acids bioavailable, various functional foods, including spreads, cookies, and other formulations, are prepared by food technologists, considering their physicochemical properties.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rumen Epithelial Transcriptome Analysis Revealed the Regulatory Mechanism of Host Adaptation to Nitrogen Source Replacement Diet in Simmental Cattle 瘤胃上皮转录组分析揭示了西蒙塔尔牛宿主对氮源替代日粮适应的调控机制。

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-28 DOI: 10.1002/fsn3.71041

Yushan Li, Xinyi Li, Xinxin Sui, Li Liu, Quratulain Hanif, Fuwen Wang, Li Luo, Ye Bu, Shanshan Xu, Yue Wang, Chuzhao Lei, Fang Sun

{"title":"Rumen Epithelial Transcriptome Analysis Revealed the Regulatory Mechanism of Host Adaptation to Nitrogen Source Replacement Diet in Simmental Cattle","authors":"Yushan Li, Xinyi Li, Xinxin Sui, Li Liu, Quratulain Hanif, Fuwen Wang, Li Luo, Ye Bu, Shanshan Xu, Yue Wang, Chuzhao Lei, Fang Sun","doi":"10.1002/fsn3.71041","DOIUrl":"10.1002/fsn3.71041","url":null,"abstract":"Soybean meal, a high-quality protein in ruminant diets, has been explored by farmers and researchers to replace soybean meal with other nitrogen sources to reduce feed costs due to its high price and limited resources. Gelatinized urea is a commonly used substitute for nitrogen source. In this study, RNA sequencing was performed on rumen epithelial tissues of Simmental beef cattle fed the diet that gelatinized urea replace 10% soybean (experimental group, n = 6) as well as Simmental beef cows fed soybean meal normally (control group, n = 4) to explore possible regulatory mechanisms in rumen tissues after nitrogen source substitution. The results showed that after the nitrogen source was replaced, the rumen epithelium may increase the nutrient absorption capacity by decreasing the degree of intercellular connectivity, increasing intercellular permeability, and possibly changing the rumen morphology, and the expression of genes related to lipoprotein synthesis was increased in the rumen epithelial tissues, which suggested that the rumen epithelium may have produced a compensatory mechanism to adapt to the changes of the nutrients in the diets.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477270/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nanoliposomal Formulation of Gynura procumbens Leaf Extract Potentiates Hepatorenal Protection in Cisplatin-Induced Rats 纳米脂质体制剂对顺铂诱导大鼠肝肾保护作用的研究。

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-28 DOI: 10.1002/fsn3.71035

Leon Bhowmik, Ashikur Rahaman, Madhobi Karmakar, S. M. M. Sharif Nowaz Antu, Zahidul Islam Zahid, Madhabi Lata Shuma, Shazid Md. Sharker, Hasan Mahmud Reza, Shimul Halder, Manik Chandra Shill

{"title":"Nanoliposomal Formulation of Gynura procumbens Leaf Extract Potentiates Hepatorenal Protection in Cisplatin-Induced Rats","authors":"Leon Bhowmik, Ashikur Rahaman, Madhobi Karmakar, S. M. M. Sharif Nowaz Antu, Zahidul Islam Zahid, Madhabi Lata Shuma, Shazid Md. Sharker, Hasan Mahmud Reza, Shimul Halder, Manik Chandra Shill","doi":"10.1002/fsn3.71035","DOIUrl":"10.1002/fsn3.71035","url":null,"abstract":"Gynura procumbens, commonly known as longevity spinach, is traditionally used in Southeast Asia for its hepatoprotective, anti-inflammatory, antihypertensive, and antihyperglycemic properties. This study aimed to enhance the hepatorenal protective effects of G. procumbens leaf extract (GLE) by incorporating it into a nanoliposomal drug delivery system (LIP), thereby improving its dispersibility/solubility and therapeutic efficacy. The resulting nano-formulation, LIP–GLE, produced micelles with an average size of 112 ± 2.6 nm, showing a 6.6-fold and 4.6-fold improvement in dispersibility in water and simulated gastric fluid, respectively, compared to GLE. In a rat model of cisplatin-induced acute hepatorenal injury (7.5 mg/kg, i.p.), oral administration of LIP–GLE (75 mg GLE/kg) significantly improved liver and kidney function, as indicated by reduced serum levels of ALT, AST, ALP, BUN, and creatinine. Histopathological investigations further confirmed reduced tissue damage in the liver and kidneys. Additionally, LIP–GLE enhanced antioxidant enzyme activities (SOD, GSH) and reduced oxidative stress markers (NO, AOPP), indicating strong protective effects against cisplatin-induced oxidative injury. These findings demonstrate that liposomal encapsulation significantly enhances the bioavailability and therapeutic potential of GLE, making it a promising approach for enhancing the nutraceutical potential of G. procumbens.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477325/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Lactiplantibacillus plantarum OLL2712 Protects From the Intestinal Dysfunction in D-Galactose Induced Senescent Cells 植物乳杆菌oll2712保护d -半乳糖诱导的衰老细胞的肠道功能障碍。

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-28 DOI: 10.1002/fsn3.71019

Yumiko Watanabe-Yasuoka, Reiko Watanabe, Ayako Gotou, Haruyo Nakajima-Adachi, Satoshi Hachimura, Toshihiro Sashihara

{"title":"Lactiplantibacillus plantarum OLL2712 Protects From the Intestinal Dysfunction in D-Galactose Induced Senescent Cells","authors":"Yumiko Watanabe-Yasuoka, Reiko Watanabe, Ayako Gotou, Haruyo Nakajima-Adachi, Satoshi Hachimura, Toshihiro Sashihara","doi":"10.1002/fsn3.71019","DOIUrl":"10.1002/fsn3.71019","url":null,"abstract":"Cellular senescence refers to a state in which cells stop dividing and can no longer proliferate because of various factors, such as DNA damage and oxidative stress. It is implicated as a key driver of aging and age-related diseases. Lactiplantibacillus plantarum OLL2712 (OLL2712) is a lactic acid bacterium that alleviates chronic inflammation and improves the intestinal barrier and cognitive functions. These effects are important for preventing the changes that occur in the body with aging. In this study, we hypothesized that OLL2712 protects against intestinal barrier dysfunction associated with cellular senescence. To reveal the antiaging effect of OLL2712, we used D-galactose (D-gal) to induce cellular senescence in Caco-2 cells and investigated its effects on various phenomena occurring in senescent intestinal cells. The results showed that OLL2712 suppressed D-gal-induced cellular senescence and intestinal barrier dysfunction. Furthermore, microarray analysis showed that OLL2712 upregulated signaling involved in antioxidant effects, metabolism, and cell division, which were downregulated by cellular senescence. Overall, OLL2712 maintained intracellular homeostasis and restored intestinal barrier dysfunction associated with cellular senescence. We discovered the possibility that paraprobiotics contribute to the antiaging effects.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477272/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Foodomics in Diabetes Management: A New Approach 饮食组学在糖尿病管理中的应用：一种新方法。

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-28 DOI: 10.1002/fsn3.71021

Sammra Maqsood, Muhammad Tayyab Arshad, Ali Ikram, Hatem A. Al-Aoh, Kodjo Théodore Gnedeka

{"title":"Foodomics in Diabetes Management: A New Approach","authors":"Sammra Maqsood, Muhammad Tayyab Arshad, Ali Ikram, Hatem A. Al-Aoh, Kodjo Théodore Gnedeka","doi":"10.1002/fsn3.71021","DOIUrl":"10.1002/fsn3.71021","url":null,"abstract":"Critical information regarding the interactions among food components, human metabolism, and disease is contained in foodomics, an interdisciplinary field that bridges food science with contemporary omics technologies (genomics, proteomics, metabolomics, and lipidomics). In order to gain a better understanding of the metabolic dysregulation in type 2 diabetes mellitus (T2DM), foodomics examines bioactive compounds derived from food (e.g., polyphenols, fibers, and lipids) alongside host molecular responses. For the enhancement of glycemic control and the prevention of diabetes-related complications, the current study is concerned with how foodomics enables personalized dietary interventions that are aligned with one's metabolic and genetic characteristics. We investigate deeper into the role of the gut microbiota in T2DM progress and how foodomics-informed methodologies, such as metabolomics and metagenomics, can be functional to discover treatments intended at the microbiota. In addition, we discover the prospective that functional foods enriched with bioactive elements, comprising β-glucans and flavonoids, may influence metabolic processes in diabetes. In addition, foodomics improves food safety by recognizing conceivable diabetes-causing contaminants (endocrine disruptors). Foodomics has incredible potential for improving precision nutrition in the prevention and treatment of T2DM, though experiments in data integration and standardization are present. Through the integration of dietary concepts, molecular biology, and clinical consequences, this method offers revolutionary strategies towards metabolic wellness.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12477330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145198760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Characterization and In Vitro Probiotic Assessment of Alkalihalobacillus wakoensis as New Potent Probiotic Candidate wakoalalihalobacillus wakoensis的特性及体外益生菌评价

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-26 DOI: 10.1002/fsn3.71031

Ali Zarei, Ahmad Gholami, Zahra Kanannejad, Aydin Berenjian, Seyed Hesamodin Nabavizadeh, Milad Mohkam

{"title":"Characterization and In Vitro Probiotic Assessment of Alkalihalobacillus wakoensis as New Potent Probiotic Candidate","authors":"Ali Zarei, Ahmad Gholami, Zahra Kanannejad, Aydin Berenjian, Seyed Hesamodin Nabavizadeh, Milad Mohkam","doi":"10.1002/fsn3.71031","DOIUrl":"https://doi.org/10.1002/fsn3.71031","url":null,"abstract":"Bacillus spp. probiotics have been shown to be promising due to their resilience in the gut. This study evaluated the in vitro probiotic potential of Alkalihalobacillus wakoensis PTCC 1596, using Bacillus clausii ATCC 700160 as a control. In vitro probiotic characteristic assays were conducted to compare A. wakoensis and B. clausii (control) in terms of acid and bile tolerance, enzymatic activity, antimicrobial potential, antibiotic susceptibility, biofilm formation, hydrophobicity, autoaggregation, enterotoxin gene presence, and cytotoxicity. A. wakoensis spores demonstrated high survival (95.6% ± 0.9%) at pH 2.5 for 3 h and tolerance to 0.5% oxgall bile salts. The strain produced catalase, protease, and nattokinase, and exhibited moderate cell surface hydrophobicity (47.1% ± 3.12% to xylene) and autoaggregation (7.0% ± 1.2% after 1 h). It showed sensitivity to several antibiotics (e.g., chloramphenicol, gentamicin) and lacked detectable plasmids and tested enterotoxin genes (hblA/hblC/hblD, nheA/nheB, bceT, and cytK). Cytotoxicity assays using HepG-2 cells indicated non-toxicity, with supernatants potentially enhancing cell viability. While exhibiting lower biofilm formation than B. clausii, A. wakoensis displayed promising traits. These findings suggest A. wakoensis PTCC 1596 is a potential probiotic candidate warranting further investigation, particularly given its alkaliphilic nature.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.71031","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Monitoring Aflatoxin M1 in Milk From Selected Iranian Provinces Using Different Assays: Seasonal Trends and Processing Effects 使用不同测定法监测伊朗选定省份牛奶中的黄曲霉毒素M1：季节趋势和加工影响

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-26 DOI: 10.1002/fsn3.71027

Hamid Reza Fathali Beygi, Mojtaba Jafari, Zohreh Ashrafi, Bahram Hassani, Razie Razavi

{"title":"Monitoring Aflatoxin M1 in Milk From Selected Iranian Provinces Using Different Assays: Seasonal Trends and Processing Effects","authors":"Hamid Reza Fathali Beygi, Mojtaba Jafari, Zohreh Ashrafi, Bahram Hassani, Razie Razavi","doi":"10.1002/fsn3.71027","DOIUrl":"https://doi.org/10.1002/fsn3.71027","url":null,"abstract":"Accurate and rapid determination of aflatoxin M1 (AFM1) is essential for ensuring the safety of milk and dairy products. This study is the first to integrate seasonal analysis, processing effects, multi-method comparison, and MOE-based risk assessment of AFM1 in Iranian milk, providing comprehensive insights for food safety monitoring. A total of 227 raw milk samples from 12 provinces were analyzed across different seasons using immunochromatography, ELISA, and HPLC. The prevalence of AFM1 exceeding the legal limit of 0.10 μg/kg, as set by the Institute of Standards and Industrial Research of Iran (ISIRI), was 9.7% in spring, 13.3% in summer, 3.7% in autumn, and 26.4% in winter. The highest average AFM1 concentrations were recorded in winter and summer, while the lowest occurred in spring and autumn. The study also evaluated the effects of pasteurization and spray-drying on AFM1 levels in skim milk and skim milk powder, with HPLC analysis showing no significant changes (p ≥ 0.05) post-processing. Risk assessment calculated the estimated daily intake (EDI) and hazard index (HI) for liver cancer, with EDI in winter reaching 62.58 ng/kg body weight and HI at 1.06, based on a tolerable daily intake (TDI) of 0.2 ng/kg bw/day derived from TD50 with a safety factor of 50,000. These results highlight the need for continuous monitoring and regulation of AFM1 to safeguard public health. Among the methods tested, immunochromatography demonstrated clear advantages over ELISA and HPLC, making it an efficient and practical tool for rapid preliminary detection of AFM1 in milk.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.71027","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

D-Carvone Mitigating Renal Damage and Enhancing Antioxidant Defense in Lithium Induced Nephrotoxicity d -香芹酮减轻锂离子引起的肾毒性及增强抗氧化防御

IF 3.8 2区农林科学

Food Science & Nutrition Pub Date : 2025-09-26 DOI: 10.1002/fsn3.70830

Semin Gedikli, Deniz Tekiner, Hülya Kara, Saime Özbek Şebin, Tubanur Aslan Engin

{"title":"D-Carvone Mitigating Renal Damage and Enhancing Antioxidant Defense in Lithium Induced Nephrotoxicity","authors":"Semin Gedikli, Deniz Tekiner, Hülya Kara, Saime Özbek Şebin, Tubanur Aslan Engin","doi":"10.1002/fsn3.70830","DOIUrl":"https://doi.org/10.1002/fsn3.70830","url":null,"abstract":"Lithium-induced nephrotoxicity presents a major health concern due to its detrimental impact on renal function, as is frequently observed in clinical and experimental settings. Despite various efforts to address this issue, effective treatment options remain limited. D-Carvone, a natural compound with antioxidants and anti-inflammatory properties, has demonstrated promise in reducing oxidative stress and inflammation. The present study aimed to explore the therapeutic impact of D-Carvone in alleviating lithium-induced nephrotoxicity, with a particular focus on oxidative stress indicators, apoptosis, inflammation, and histological changes in renal tissue. To this end, a total of 24 male rats were divided into four groups: Control, Lithium, Lithium + D-Carvone (20 mg/kg daily), and D-Carvone alone, with six animals per group. Lithium-induced nephrotoxicity was evaluated over 14 days. Oxidative stress was measured by evaluating malondialdehyde (MDA), glutathione (GSH) levels, and superoxide dismutase (SOD) activity. The expression of Caspase-3, Bcl-2, HO-1, TLR4, NRF2, and NF-κB-p65 was analyzed to assess apoptotic, inflammatory, and oxidative stress pathways. A histopathological examination of the kidney cortex and medulla was conducted. The results revealed that lithium administration caused significant histological damage, increased oxidative stress, and altered apoptotic and inflammatory protein expression. D-Carvone treatment reduced lipid peroxidation, restored apoptotic protein balance, alleviated inflammation, and protected renal tissue. These findings highlight the potential of D-Carvone as an adjuvant therapy for mitigating the nephrotoxic effects of lithium.","PeriodicalId":12418,"journal":{"name":"Food Science & Nutrition","volume":"13 10","pages":""},"PeriodicalIF":3.8,"publicationDate":"2025-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/fsn3.70830","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145135770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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