Bruno Halioua, Patrick Bantman, Rachel Rimmer, Eric Ghozlan, Muriel Vaislic, Dan Halioua, Fabienne Amson, Charles Taieb, Richard Prasquier, Jean-François Gutthman, Robert Ejnes, Stéphanie Dassa, Alexis Astruc, Marc Cohen, Samuel Sarfati, Marc Fohlen-Weill, Odile Namia-Cohen, Aline Deutscher, Jonathan Taieb
{"title":"International study of the perceived stress and psychological impact of the 7 October attacks on Holocaust survivors.","authors":"Bruno Halioua, Patrick Bantman, Rachel Rimmer, Eric Ghozlan, Muriel Vaislic, Dan Halioua, Fabienne Amson, Charles Taieb, Richard Prasquier, Jean-François Gutthman, Robert Ejnes, Stéphanie Dassa, Alexis Astruc, Marc Cohen, Samuel Sarfati, Marc Fohlen-Weill, Odile Namia-Cohen, Aline Deutscher, Jonathan Taieb","doi":"10.1080/20008066.2024.2428025","DOIUrl":"10.1080/20008066.2024.2428025","url":null,"abstract":"<p><p><b>Objective:</b> The terrorist attacks of 7 October 2023 in southern Israel had a significant impact on the mental health of Holocaust Survivors (HS), who are considered to be particularly vulnerable to traumatic events. The aim of the study was to assess the severity of perceived stress and the psychological impact of the 7 October attacks on HS.<b>Methods:</b> The study was conducted from 30 October to 15 December 2023 among HS who were contacted through HS support organisations (OSE, Aloumim). They completed a questionnaire consisting of four sections: socio-demographic data and experiences during the Holocaust, assessment of psychological stress using the Perceived Stress Scale (PSS-10), feelings of isolation, health consequences, and reactions to the 7 October attacks.<b>Results:</b> 171 HS completed the questionnaire with 61 males (35.7%) with a mean age of 86.6+/-4.4 years (min 79-max 97). 59.6%, lived outside Israel, mainly in France. The mean score on the PSS-10 was 17.7 +/-6.0 on a scale of 5 to 40. The average PSS 10 score is not significantly higher in cases of age ≤90 years (18.0 ± 6.0 vs 15.7 ± 6.4, NS), or for those living in Israel (17.2 ± 5.3 vs 18.1 ± 6.6, NS). About a quarter reported feelings of isolation or loneliness following the attacks. The impact of the 7 October attacks was particularly significant among those living outside Israel. Approximately two-thirds felt that the events had rekindled memories of their Holocaust experiences, and nearly one-third observed a decline in their health since the attacks. Among survivors living outside Israel, 86.6% expressed concern about the future safety and identity of their children and grandchildren as Jews.<b>Conclusion:</b> Identifying Holocaust survivors (HS) who are experiencing psychological distress is crucial to providing them with appropriate therapy.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2428025"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11792156/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122505","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rana Selin Kucukardali, Beyza Nur Karal, Alan M Steinberg, Abdurrahman Cahid Orengul
{"title":"Psychometric evaluation of the UCLA PTSD Reaction Index (PTSD RI-5) in a Turkish Clinical sample of trauma-exposed children.","authors":"Rana Selin Kucukardali, Beyza Nur Karal, Alan M Steinberg, Abdurrahman Cahid Orengul","doi":"10.1080/20008066.2025.2465082","DOIUrl":"10.1080/20008066.2025.2465082","url":null,"abstract":"<p><p><b>Objective:</b> Trauma victimization is common among children, however, a significant proportion of trauma victims go unrecognized unless they are thoroughly assessed, even in child psychiatry clinics. The aim of this study was to evaluate the psychometric properties and diagnostic accuracy of the Turkish version of the UCLA PTSD Reaction Index for DSM-5 (PTSD RI-5) in a clinical sample of trauma-exposed children and adolescents.<b>Method:</b> A total of 208 children and adolescents admitted to the child psychiatry clinic, each of whom had a history of at least one traumatic event, were evaluated with the PTSD RI-5 to investigate trauma history and PTSD symptoms. All participants also completed the Revised Child Anxiety and Depression Scale (RCADS) and 64 participants were assessed with a semi-structured diagnostic interview for PTSD and depression.<b>Results:</b> Internal consistency for the total scale was high (Cronbach's α = 0.91) and the confirmatory factor analysis (CFA) supported the four-factor structure of the PTSD RI-5 (CFI = 0.915, TLI = 0.902, RMSEA =0.062). ROC analysis showed strong diagnostic accuracy (AUC = 0.94).<b>Conclusion:</b> The Turkish version of the PTSD RI-5 may a reliable and valid tool for diagnosing PTSD in clinical samples and may improve diagnosis and treatment outcomes by identifying unrecognized trauma-related symptoms.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2465082"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852236/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482549","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Psychometric properties of the revised Ukrainian version of the Continuous Traumatic Stress Response scale (CTSR) in the context of the Russo-Ukrainian war.","authors":"Iryna Frankova, Oksana Senyk, Oleksandr Avramchuk, Iryna Leshchuk, Andrii Rudys, Anton Kurapov, Aviva Goral","doi":"10.1080/20008066.2025.2463186","DOIUrl":"10.1080/20008066.2025.2463186","url":null,"abstract":"<p><p><b>Background:</b> The Continuous Traumatic Stress Response scale (CTSR) was designed to measure symptoms associated with multiple ongoing security threats in the context of Israeli-Palestinian conflict. Since 2014, Ukraine has faced armed invasion and war, with nationwide insecurity since February 2022.<b>Objective:</b> This study aimed to adapt the CTSR scale into Ukrainian and evaluate its psychometric properties within a Ukrainian sample during the ongoing war.<b>Method:</b> The Ukrainian adaptation of the CTSR followed the procedure used in creating the original instrument (Goral, A., Feder-Bubis, P., Lahad, M., Galea, S., O'Rourke, N., & Aharonson-Daniel, L. (2021). Development and validation of the Continuous Traumatic Stress Response scale (CTSR) among adults exposed to ongoing security threats. <i>PLoS One</i>, <i>16</i>(5), e0251724). To identify a unique context-specific factor structure relevant to the Ukrainian experience, the initial 25 items were tested in a sample of 584 Ukrainians using exploratory and confirmatory factor analyses. Subsequently, the established scale structure was assessed for homogeneity, and convergent validity using measures of depression (PHQ-9), anxiety (GAD-7), perceived stress (PSS-4), resilience (BRS), and PTSD symptoms (PCL-5).<b>Results:</b> A three-factor, 9-item solution, representing the constructs of exhaustion, alienation, and helplessness, demonstrated the most acceptable fit among all the alternative CTSR models, including the original: χ<sup>2</sup> = 72.84, df = 24, <i>p</i> < .001, χ<sup>2</sup>/ (df) = 3.04, CFI = 0.94, TLI = 0.91, SRMR = 0.05, RMSEA = 0.08. Cronbach's α for internal consistency ranged from 0.68 to 0.84 for total score, and subscales. Significant positive correlations ranging from 0.41 to 0.67 with symptom severity of depression, anxiety, perceived stress, and PTSD established the convergent validity of the Ukrainian CTSR, indicating that it measures related yet distinctive psychological phenomena of reactions to continuous traumatic stress.<b>Conclusions:</b> The revised Ukrainian version of the CTSR scale is a reliable and valid measure of continuous traumatic stress response, accurately reflecting its manifestation in the Ukrainian context. These findings are crucial for guiding clinical interventions and research in prolonged war environments, where understanding the nuances of ongoing trauma is essential.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2463186"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852225/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shilat Haim-Nachum, Amit Lazarov, John C Markowitz, Maja Bergman, Yossi Levi-Belz, Ido Lurie, Milton L Wainberg, Shlomo Mendlovich, Yuval Neria, Doron Amsalem
{"title":"Treatment stigma mediates relationships between morally injurious events and depression, PTSD and anxiety symptoms.","authors":"Shilat Haim-Nachum, Amit Lazarov, John C Markowitz, Maja Bergman, Yossi Levi-Belz, Ido Lurie, Milton L Wainberg, Shlomo Mendlovich, Yuval Neria, Doron Amsalem","doi":"10.1080/20008066.2025.2471659","DOIUrl":"10.1080/20008066.2025.2471659","url":null,"abstract":"<p><p><b>Background:</b> Morally injurious events (MIEs), encompassing personal transgressions, witnessing others commit transgressions, or experiencing betrayal by leaders, can conflict with one's moral/ethical principles, evoking outrage and profound mistrust. Although MIEs are associated with depression, PTSD, and anxiety, the mechanisms linking MIEs to psychiatric symptomatology remain unclear, especially among civilians in times of collective trauma.<b>Objective:</b> This study explored one potential mechanism: stigma toward mental-health treatment, which can deter help-seeking and exacerbate guilt, shame, and mistrust.<b>Method:</b> We focused on civilians (<i>N </i>= 1,052) exposed to MIEs in conflict zones in southern and northern Israel following the 7 October 2023 attack. Participants were recruited using an online platform and assessed for depression, PTSD, and anxiety symptoms. We hypothesised that stigma toward treatment would mediate relationships between MIE exposure levels and depression, PTSD, and anxiety symptoms.<b>Results:</b> Results showed high MIE exposure levels and symptomatology among civilians in conflict zones. Moreover, we found significant indirect effects of stigma toward treatment on all three symptom types.<b>Conclusions:</b> Our findings suggest that while MIEs directly link to symptoms, stigma toward treatment plays a significant role in understanding this link. These findings emphasise the importance of addressing stigma toward treatment for individuals experiencing MIEs and underscore the need for targeted interventions in conflict zones.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2471659"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11894749/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143585113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Line Rønning, Rachel L Zelkowitz, Marilyn L Piccirillo, Jianlin Liu, Jordan L Thomas, Jessy Guler, J Joana Kyei, Chris M Hoeboer, Jeanet F Karchoud, Miranda Olff, Anke B Witteveen, Mirjam van Zuiden
{"title":"Gender differences in early posttraumatic stress disorder symptoms: a network analysis.","authors":"Line Rønning, Rachel L Zelkowitz, Marilyn L Piccirillo, Jianlin Liu, Jordan L Thomas, Jessy Guler, J Joana Kyei, Chris M Hoeboer, Jeanet F Karchoud, Miranda Olff, Anke B Witteveen, Mirjam van Zuiden","doi":"10.1080/20008066.2024.2448385","DOIUrl":"10.1080/20008066.2024.2448385","url":null,"abstract":"<p><p><b>Background:</b> Despite known gender/sex differences in the prevalence of posttraumatic stress disorder (PTSD), potential differences in the associations among PTSD symptoms between men and women in the early post-trauma period are not well-characterized.<b>Objective:</b> This study utilized network analysis to assess potential differences in the associations among PTSD symptom clusters between men and women during the early post-trauma period.<b>Method:</b> We included <i>n</i> = 475 participants (57.5% self-identified women) who recently (≤2 months) experienced an interpersonal or motor vehicle potential traumatic event in the Netherlands. Past month PTSD symptoms were measured with the PTSD Checklist for DSM-5 (PCL-5) and composited according to the five-node PTSD symptom cluster dysphoric arousal model. We estimated the network as well as indices of centrality (strength and predictability) and assessed the stability of the modelled networks in subsamples of men (<i>n </i>= 202) and women (<i>n </i>= 273). We compared network structures using the Network Comparison Test (NCT).<b>Results:</b> Results largely demonstrated adequate correlation stability for the estimated network structures for women and men. For both men and women, avoidance symptoms were among the strongest nodes with greatest predictability in the networks. In men, anxious arousal additionally showed high strength whereas re-experiencing showed high predictability. In women, re-experiencing symptoms demonstrated both high strength and predictability. The NCT demonstrated nonsignificant differences in global network structure (<i>M </i>= 0.08, <i>p</i> = .054) and strength (<i>S</i> = .073, <i>p</i> = .067). Post hoc comparisons showed an association of re-experiencing symptoms with negative alterations in cognitions and mood in men but not women (<i>E</i> = .038, <i>p</i> = .005).<b>Conclusion:</b> Results demonstrated possible modest gender differences in aspects of network structure although most elements of the network structure were similar across genders. These results help to characterize gender differences in associations among PTSD symptom clusters during the early post-trauma period, which may inform the potential relevance of future gender-sensitive early intervention strategies to ameliorate the risk for long-term PTSD.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2448385"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11758801/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143022554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The interpersonal theory of suicide risk in male US service members/veterans: the independent effects of perceived burdensomeness and thwarted belongingness.","authors":"Rebecca K Blais, Kevin J Grimm","doi":"10.1080/20008066.2024.2439748","DOIUrl":"10.1080/20008066.2024.2439748","url":null,"abstract":"<p><p><b>Introduction:</b> Suicide rates remain high among US military service member/veteran (SM/V) males with overall trends showing an upward trajectory. Several empirical studies and official US government reports show that interpersonal challenges can substantially increase suicide risk. One theory, the Interpersonal Theory of Suicide (IPT), focuses thwarted belongingness, perceived burdensomeness, capability for suicide, and their interactions, as key contributors to suicide risk. Extant military studies are subscribed to specific subsamples and/or do not test the full theory. This has resulted in mixed findings or findings with limited generalizability. The current study addressed these limitations.<b>Method:</b> A convenience sample of 508 male SM/Vs completed self-report measures of lifetime suicide ideation, likelihood of making a future attempt, thwarted belongingness, perceived burdensomeness, capability for suicide, and demographics. Suicide ideation and risk was regressed on IPT variables, relevant interactions, and covariates.<b>Results:</b> The variance accounted for in suicide ideation and likelihood of a future attempt was 32% and 62%, respectively. Higher perceived burdensomeness was associated with suicide ideation, and higher thwarted belongingness had a marginally significant association with suicide ideation. The presence of suicide ideation and higher thwarted belongingness were associated with the likelihood of making a future attempt. Capability for suicide was not associated with the likelihood of making a future attempt.<b>Discussion:</b> Perceived burdensomeness, suicide ideation, and thwarted belongingness appear to individually create risk for future suicide behaviour among US military service members and veterans. Additional work is needed to establish comprehensive theories of suicide risk in this population.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2439748"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11795748/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143188654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lorika Shkreli, Marcella L Woud, Luisa Bergunde, Lena Schindler-Gmelch, Simon E Blackwell, Clemens Kirschbaum, Henrik Kessler, Susann Steudte-Schmiedgen
{"title":"The role of long-term hair steroids as diagnostic and intervention-related biomarkers in a multimorbid inpatient sample with posttraumatic stress disorder.","authors":"Lorika Shkreli, Marcella L Woud, Luisa Bergunde, Lena Schindler-Gmelch, Simon E Blackwell, Clemens Kirschbaum, Henrik Kessler, Susann Steudte-Schmiedgen","doi":"10.1080/20008066.2025.2457295","DOIUrl":"10.1080/20008066.2025.2457295","url":null,"abstract":"<p><p><b>Background:</b> Steroid hormone dysregulations have frequently been implicated in posttraumatic stress disorder (PTSD) pathogenesis. However, the translation into naturalistic clinical settings as markers of symptomatology and treatment success remains complex. Particularly, there is little longitudinal data on steroid secretion over the course of interventions.<b>Objective:</b> This study examined the potential of long-term steroid hormone secretion assessed in hair as diagnostic and intervention-related biomarkers among medicated, multimorbid inpatients with PTSD.<b>Method:</b> As part of a secondary analysis of a randomised controlled trial, 54 female inpatients with a primary diagnosis of PTSD received standardised treatment and provided hair samples at pre-treatment, post-treatment, and 3-month follow-up. Cortisol, cortisone, and dehydroepiandrosterone (DHEA) were determined, alongside clinical assessments.<b>Results:</b> Cross-sectional results showed a negative association of pre-treatment DHEA with anxiety symptoms and a trend-level association with lifetime trauma exposure. While inpatients improved in PTSD symptomatology during treatment, neither pre-treatment steroids, nor treatment-induced steroid changes predicted PTSD symptoms at post-treatment or 3-month follow-up.<b>Conclusion:</b> The study highlights the challenges of establishing biomarkers in naturalistic clinical populations. While the association of attenuated DHEA with anxiety symptoms warrants further exploration, our data points towards the potential necessity of patient sub-sample selection to understand, and in the long run clinically target, the endocrine mechanisms in PTSD.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2457295"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11852232/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143482551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ole Melkevik, Anni B S Nielsen, Katrine Friis, Caroline Lund, Bjarke W Schmidt, Sofie Folke
{"title":"Validation of a clinician-administered diagnostic measure of ICD-11 PTSD and complex PTSD: the International Trauma Interview in a clinical sample of military veterans.","authors":"Ole Melkevik, Anni B S Nielsen, Katrine Friis, Caroline Lund, Bjarke W Schmidt, Sofie Folke","doi":"10.1080/20008066.2025.2465217","DOIUrl":"10.1080/20008066.2025.2465217","url":null,"abstract":"<p><p><b>Background:</b> The International Trauma Interview (ITI) is the first clinician-administered diagnostic tool developed to assess posttraumatic stress disorder (PTSD) and Complex PTSD (CPTSD), both recently recognized in the ICD-11. The current study aims to test the construct and discriminant validity of the ITI in a population of treatment-seeking veterans.<b>Method:</b> 124 Danish veterans seeking psychological treatment were interviewed by a group of trained clinicians for ICD-11 PTSD and CPTSD before beginning treatment at the Military Psychological Department in the Danish Defense. A series of confirmatory factor models were estimated in order to identify the extent to which latent variable operationalizations provide potential explanations for the associations between symptoms.<b>Results:</b> Results indicate that symptoms of CPTSD, as measured by the ITI, are best represented by a single higher-order factor. We also found that a bifactor model provided adequate fit to the data. The commonly identified two-factor higher-order model was rejected due to the lack of discriminant validity between PTSD and DSO. The higher order model was found to explain associations between symptoms of CPTSD and symptoms of depression, stress, anxiety, and well-being.<b>Conclusion:</b> The ITI does not fit a two-factor higher-order model in a sample of treatment-seeking Danish veterans. Rather, a single higher order factor shows excellent fit, and is found to explain associations between ITI symptoms and other internalizing symptoms.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2465217"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11866645/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143499993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Alice Demesmaeker, Coralie Creupelandt, Arnaud Leroy, Guillaume Vaiva, Fabien D'Hondt
{"title":"Impact of posttraumatic stress disorder and comorbid psychiatric conditions on suicide reattempts.","authors":"Alice Demesmaeker, Coralie Creupelandt, Arnaud Leroy, Guillaume Vaiva, Fabien D'Hondt","doi":"10.1080/20008066.2025.2461435","DOIUrl":"10.1080/20008066.2025.2461435","url":null,"abstract":"<p><p><b>Background:</b> Posttraumatic stress disorder (PTSD) is a prevalent psychiatric condition that significantly increases the risk of suicide.<b>Objective:</b> This study aimed to assess PTSD and its co-occurring conditions among individuals who attempted suicide and to evaluate the relationship between these disorders and suicide reattempts within six months.<b>Method:</b> This prospective cohort study included 2,441 individuals from the French Vigilans programme who attempted suicide between 2015 and 2020. Data on sociodemographic characteristics and suicide attempt (SA) history were collected at baseline, and lifetime psychiatric conditions were assessed via the Mini-International Neuropsychiatric Interview (MINI) during the six-month follow-up telephone interview. Multivariate logistic and linear regression models were used to measure the impact of PTSD and its comorbidities on suicide reattempts within six months, controlling for sex, age, and prior SAs.<b>Results:</b> In total, 11.8% of the individuals (287/2,441) in the cohort were diagnosed with PTSD. Among these, 71.1% (204/287) had major depressive disorder, 36.2% (104/287) had alcohol use disorder, and 35.9% (103/287) had panic disorder. Within six months, we observed higher rates of suicide reattempt in those with PTSD (<i>p </i>< .01; <i>OR</i> 1.71 95% CI 1.14-2.55), regardless of comorbidities. Even higher rates were found in those with PTSD comorbid with panic disorder (<i>p </i>= .02 <i>OR</i> 1.95 95% CI 1.12-3.39) or substance use disorder (<i>p </i>= .01 <i>OR</i> 2.91 95% CI 1.28-6.62). Additionally, PTSD comorbid with panic disorder (<i>p </i>= .02, <i>β </i>= .10) or eating disorders (<i>p </i>= .04, <i>β </i>= .12) was associated with a greater number of suicide reattempts.<b>Conclusion:</b> Approximately one in ten SA survivors experienced PTSD. Individuals with PTSD and comorbid conditions, such as panic disorder, substance use disorder, and eating disorders, are two to three times more likely to reattempt suicide within six months. Despite ongoing preventive efforts, rates of reattempt remain high, highlighting the urgent need for continuous clinical monitoring and personalized therapeutic interventions.<b>Trial registration:</b> ClinicalTrials.gov identifier: NCT03134885.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2461435"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11823379/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143398673","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Antje Krüger-Gottschalk, Sascha T Kuck, Anne Dyer, Georg W Alpers, Andre Pittig, Nexhmedin Morina, Thomas Ehring
{"title":"Effectiveness in routine care: trauma-focused treatment for PTSD.","authors":"Antje Krüger-Gottschalk, Sascha T Kuck, Anne Dyer, Georg W Alpers, Andre Pittig, Nexhmedin Morina, Thomas Ehring","doi":"10.1080/20008066.2025.2452680","DOIUrl":"10.1080/20008066.2025.2452680","url":null,"abstract":"<p><p><b>Objective</b>: The efficacy of trauma-focused cognitive behaviour therapy (tf-CBT) has been well established in randomized controlled trials (RCTs). More research is needed to demonstrate the effectiveness of tf-CBT in routine clinical care settings.<b>Method</b>: Eighty-five patients (68 female) with a primary diagnosis of PTSD received tf-CBT at two German outpatient centres (Münster and Mannheim) between 2014 and 2016. Treatment was delivered mainly by therapists in training and treatment duration was based on symptom course. The treatment consisted of a preparation phase, a trauma-focused phase (comprising imaginal exposure, discrimination training, changing dysfunctional appraisals) and a phase of reclaiming-your-life assignments, and relapse prevention. In an intent-to-treat-analysis (ITT), linear mixed effects models were fitted for self-assessments of traumatic symptom severity using the PTSD Checklist for DSM-5 (PCL-5) and the Clinician-Administered PTSD Scale for DSM-5 (CAPS-5). Potential moderators for treatment outcome, e.g. number of suicide attempts, were investigated.<b>Results</b>: The observed treatment effect was large for both the CAPS-5 (ITT: Cohen's <i>d</i> = 2.07, CI [1.62, 2.51]; completers <i>d</i> = 2.34, CI [1.84, 2.83]) and PCL-5 respectively (ITT: <i>d</i> = 2.02, CI [1.56, 2.48]; completers <i>d</i> = 2.15, CI [1.66, 2.64]), and remained stable six months and one-year post-treatment. <i>N</i> = 27 patients (31.48%) were defined as study dropout and of these, <i>n</i> = 12 (14.12%) dropped out of the study but completed treatment. None of the fixed-effect estimates for treatment predictors interacted significantly with the effect of time.<b>Conclusions</b>: Tf-CBT is well-tolerated and it can be effectively delivered in routine clinical care. Its large treatment effects underline the practicability and benefits of the approach. This trial demonstrates its broad applicability among individuals with diverse patterns of clinical characteristics and comorbidities.</p>","PeriodicalId":12055,"journal":{"name":"European Journal of Psychotraumatology","volume":"16 1","pages":"2452680"},"PeriodicalIF":4.2,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11827035/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143406253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}