Ecotoxicology最新文献_第3页

Cumulative effect of chronic thermal stress and glyphosate based herbicide exposure on blood parameters and cortisol levels of common carp (Cyprinus carpio). 慢性热应激和草甘膦除草剂暴露对鲤鱼血液参数和皮质醇水平的累积影响。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-20 DOI: 10.1007/s10646-025-02875-y

Imran Khan, Fakhr Ul Islam, Naimat Ullah Khan, Hazrat Ali, Mohammad Attaullah, Muhammad Ikram Khan

{"title":"Cumulative effect of chronic thermal stress and glyphosate based herbicide exposure on blood parameters and cortisol levels of common carp (Cyprinus carpio).","authors":"Imran Khan, Fakhr Ul Islam, Naimat Ullah Khan, Hazrat Ali, Mohammad Attaullah, Muhammad Ikram Khan","doi":"10.1007/s10646-025-02875-y","DOIUrl":"https://doi.org/10.1007/s10646-025-02875-y","url":null,"abstract":"Climate change and environmental pollution can alter the composition and productivity of biological communities in aquatic ecosystems. Sensitive species are at more risk due to these stressors, which can affect their physiology with adverse effects on their health and reproduction. Co-exposure to multiple environmental stressors may have synergistic effects on the health of aquatic animals. Therefore, present research was designed to explore the cumulative effect of chronic exposure to thermal stress and glyphosate-based herbicide on the hematological parameters and cortisol level of common carp (Cyprinus carpio). Twenty-eight common carp were exposed to thermal stress (30 and 32 °C temperature) and a sub-lethal concentration of glyphosate for 28 days. A significant increase in white blood cells (WBCs), platelets and cortisol was observed in fish exposed to the sub-lethal concentration of glyphosate, while red blood cells (RBCs) and hemoglobin (Hb) decreased. Cortisol levels of fish exposed to thermal stress (32 °C) increased significantly. RBCs, WBCs, platelets, hemoglobin concentration and cortisol levels increased significantly in fish co-exposed to thermal stress and a sub-lethal concentration of glyphosate. It was concluded that co-exposure to glyphosate and thermal stress causes physiological impairments in common carp.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143669457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive machine learning assessment of zebrafish behaviour and biochemical markers in response to caffeine exposure. 斑马鱼对咖啡因暴露的行为和生化标志物的综合机器学习评估。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-19 DOI: 10.1007/s10646-025-02873-0

Cláudia Teixeira, Sara Rodrigues, João Amorim, Bárbara S Diogo, Ivo Pinto, António Paulo Carvalho, Sara C Antunes, Luís Oliva Teles

{"title":"Comprehensive machine learning assessment of zebrafish behaviour and biochemical markers in response to caffeine exposure.","authors":"Cláudia Teixeira, Sara Rodrigues, João Amorim, Bárbara S Diogo, Ivo Pinto, António Paulo Carvalho, Sara C Antunes, Luís Oliva Teles","doi":"10.1007/s10646-025-02873-0","DOIUrl":"https://doi.org/10.1007/s10646-025-02873-0","url":null,"abstract":"Environmental exposure to caffeine (CAF) poses potential risks to aquatic ecosystems, affecting non-target species. This study investigated the chronic effects of environmentally relevant CAF concentrations, ranging from 0.16-50 µg/L, on zebrafish behaviour. A Kohonen-type artificial neural network classified zebrafish behaviour into nine behavioural classes based on a set of movement descriptors (mean meander, mean velocity, instantaneous velocity, distance to centre point, mean angular velocity and instantaneous acceleration), while a comprehensive analysis integrated behavioural classes previously defined and biochemical markers of oxidative stress, lipid peroxidation, reserve energy content, energetic pathways, and neurotoxicity. The discriminant analysis demonstrated that behaviour descriptors and biomarkers individually explained 38% and 67% of data variation, respectively, while the combination resulted in 19 models with 100% correct diagnosis. One of the models (Model A) seemed to suit the best dose-response relationship, incorporating key biomarkers including superoxide dismutase, catalase, glutathione peroxidase activities, and behavioural characteristics such as movement distance and velocity. This suggested methodology offers a different approach to evaluating CAF's ecological impact, highlighting behavioural analysis as a valuable complement to traditional ecotoxicological assessments. This study provides a novel framework for understanding organism-level responses to environmental stressors (e.g., several anthropogenic compounds), utilising Mahalanobis distance as an integrative response index. This approach shows promise for broader application in assessing the impact of various aquatic contaminants on aquatic organisms (from bacteria to fish), potentially extending to pharmaceuticals, pesticides, and industrial pollutants.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Phytotoxicity of seven iron-based materials to mung bean seedlings. 7种铁基材料对绿豆幼苗的毒性研究。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-18 DOI: 10.1007/s10646-025-02858-z

Fang Zuo, Wenjie Wang, Zhihang Shao, Yuhuan Sun, Fayuan Wang

{"title":"Phytotoxicity of seven iron-based materials to mung bean seedlings.","authors":"Fang Zuo, Wenjie Wang, Zhihang Shao, Yuhuan Sun, Fayuan Wang","doi":"10.1007/s10646-025-02858-z","DOIUrl":"https://doi.org/10.1007/s10646-025-02858-z","url":null,"abstract":"Due to the widespread application of various iron-based materials in environmental remediation and agricultural production, it is of significance to assess their environmental risks. Here, seven iron-based materials, including ionic FeCl3, micro- and nano-sized magnetite (i.e., mFe3O4 and nFe3O4), micro- and nano-sized zero-valent iron (i.e., mZVI and nZVI), and nZVI modified by starch and activated carbon (i.e., S-nZVI and A-nZVI), were targeted to compare their phytotoxicity in mung bean grown in the soil with different doses (0, 300, 600, and 1000 mg/kg) for 40 days. S-nZVI and A-nZVI severely inhibited plant growth, decreasing shoot and root dry weights by 45.1-79.2 and 26.0-82.3%, respectively, but other materials showed no or minimal effects on plant growth. All the materials decreased chlorophyll content and photosynthesis performance, with more pronounced inhibition from A-nZVI and S-nZVI, especially at 1000 mg/kg. The activities of superoxide dismutase (SOD) and peroxide dismutase (POD) in leaves were stimulated by all the materials, among which S-nZVI enhanced SOD activity by 206.9% at 300 mg/kg and POD activity by 541.1% at 1000 mg/kg. In most cases, Fe accumulation in the roots was increased by all materials, particularly by S-nZVI and A-nZVI. Fe concentrations in roots and shoots exposed to 1000 mg/kg S-nZVI and A-nZVI were 2-3 times higher than those in the control treatments. The disturbance in the homeostasis of minerals (Zn, Mn, Cu, and Mg) was induced by all iron-based materials. To conclude, the phytotoxicity of iron-based materials was dependent on their type and dosage, and stabilization was crucial for the phytotoxicity and bioaccumulation potential of nZVI in plants.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of herbicide formulations and spreading agents on survival of the bumblebee Bombus impatiens following spray and contact exposure. 除草剂配方和扩散剂对大黄蜂喷雾和接触后存活率的影响。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-18 DOI: 10.1007/s10646-025-02876-x

Ryleigh V Gelles, Thomas S Davis

{"title":"Evaluation of herbicide formulations and spreading agents on survival of the bumblebee Bombus impatiens following spray and contact exposure.","authors":"Ryleigh V Gelles, Thomas S Davis","doi":"10.1007/s10646-025-02876-x","DOIUrl":"https://doi.org/10.1007/s10646-025-02876-x","url":null,"abstract":"Surfactants are often included as co-formulants in the application of herbicides to aid in spreading and adherence to plant surfaces, but toxicity to native bees has not been extensively tested. In a set of progressive experiments, we evaluated effects of products containing glyphosate and spreading agents, as well as spreading agents alone, on bumblebees (Bombus impatiens Cresson) using parametric survival analysis. We test spreaders from multiple chemical classes including Silwet L-77© (trisiloxane), Alligare 90© (polyoxyethylene), and Southern Ag SA-50© (C10-16 alcohols). We report low lethality of high-glyphosate herbicide formulations (Rodeo©), but bee mortality increased ~20% with addition of a silicone-based spreading agent (Silwet L-77©). Spreaders alone strongly affected bee survival: effects were concentration-specific and did not differ depending on exposure method (spray application vs. application to surfaces contacted by bees). The widely used trisiloxane-based spreader Silwet L-77© was especially hazardous, and exposure to high concentrations of Silwet L-77© caused rapid and near-total mortality in B. impatiens. Analysis of whole-bee cuticle extracts after exposure revealed clear differences in the cuticular hydrocarbon profiles associated with exposure to spreading agents: the alkane n-hexacosane was present in all extracts but was detected in greater relative abundance from bees exposed to Silwet L-77© and Alligare 90©. To support wild bee conservation efforts, we recommend substituting alcohol-based spreaders for siloxane-based spreaders when possible. In addition, certain cuticular hydrocarbons may be useful as biomarkers of previous exposure to certain surfactants, which can aid investigations evaluating causes of bumblebee decline across landscapes.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Combined effects of ocean acidification and copper exposure on the polyps of moon jellyfish Aurelia coerulea. 海洋酸化和铜暴露对月亮水母珊瑚虫的联合影响。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-17 DOI: 10.1007/s10646-025-02869-w

Lei Wang, Fanghan Wang, Yuanqing Ma

{"title":"Combined effects of ocean acidification and copper exposure on the polyps of moon jellyfish Aurelia coerulea.","authors":"Lei Wang, Fanghan Wang, Yuanqing Ma","doi":"10.1007/s10646-025-02869-w","DOIUrl":"https://doi.org/10.1007/s10646-025-02869-w","url":null,"abstract":"Ocean acidification (OA) can interact with Copper (Cu) pollutants and threaten marine organisms and ecosystems. In this study, we assessed the effects of OA and Cu2+, alone and in combination, on the polyps of Aurelia coerulea, a common jellyfish renowned for its complex life cycle and frequent global blooms. The results revealed that ocean acidification and Cu2+ exposure significantly inhibited the activities of catalase, Ca2+-ATPase, acid phosphatase, and alkaline phosphatase in polyps, resulting in antioxidative stress effects and a significant increase in respiratory metabolism. In addition, the combination of ocean acidification and Cu2+ exposure caused severe tissue damage to polyps, thereby impeding their predation behavior and reducing their asexual reproduction rates. These two environmental stressors showed synergistic effects on the Ca2+-ATPase activity, predation rate, reproduction rate, and injury index of polyps. Therefore, reduced seawater pH and copper contamination adversely affect the physiology, growth, and development of A. coerulea polyps, which may affect the survival and population dynamics of wild populations.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short- and medium-term effects of biodegradable microplastics (PLA and PHB) on earthworm development and reproduction. 可生物降解微塑料（PLA和PHB）对蚯蚓发育和繁殖的中短期影响。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-17 DOI: 10.1007/s10646-025-02868-x

David Gutiérrez-Rial, Aarón Lagoa, Iria Villar, Pilar Feijoo, Fuencisla Mariño, Josefina Garrido, Benedicto Soto, Salustiano Mato

{"title":"Short- and medium-term effects of biodegradable microplastics (PLA and PHB) on earthworm development and reproduction.","authors":"David Gutiérrez-Rial, Aarón Lagoa, Iria Villar, Pilar Feijoo, Fuencisla Mariño, Josefina Garrido, Benedicto Soto, Salustiano Mato","doi":"10.1007/s10646-025-02868-x","DOIUrl":"https://doi.org/10.1007/s10646-025-02868-x","url":null,"abstract":"Microplastics derived from biobased and biodegradable materials will increase their presence in soils as their use becomes more widespread. Research into their effects on soil fauna will help to ensure a better understanding of their environmental impacts. The aim of this work was to study the effects on the development of the earthworm Eisenia andrei (ingestion capacity, survival, growth, cocoon, and hatchling production), earthworm lysosomal stability through the neutral red retention time (NRTT), and substrate enzymatic activity of dehydrogenase (DHA) and fluorescein diacetate-hydrolysing activity (FDA) in the presence of polylactic acid (PLA), polyhydroxybutyrate (PHB) and polyethylene (PE) microplastics in laboratory tests. Three different tests were designed, one feeding test of 4 days, and two medium-term tests with 49 and 112 days. The 4-day test and the 49-day growth test were carried out using OECD artificial soil, while in the 112-day growth test, vermicompost was used as the substrate. PLA and PHB particle ingestion was demonstrated. No concentration or polymer-dependent lysosomal damage or effects on earthworm growth were observed. However, reproductive effects, such as a decrease in cocoon production and the number of juveniles, were reported upon exposure to PE and PLA during medium-term assays. These findings indicated that the toxicity of PLA bioplastic exposure is comparable to that of conventional plastic PE concerning the negative effects on the reproductive efficiency of the detritivorous earthworm E. andrei.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Locomotion (behavioural) test in the terrestrial oligochaetes Eisenia exposed to carbamate model substance. 暴露于氨基甲酸酯模型物质的陆生寡毛藻运动（行为）试验。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-15 DOI: 10.1007/s10646-025-02870-3

Antonio Calisi, Mario Angelelli, Davide Gualandris, Davide Rotondo, Giorgio Mancinelli, Francesco Dondero

引用次数: 0

The induced hepatotoxicity and genotoxicity in Oreochromis niloticus exposed to a newly released florpyrauxifen-benzyl herbicide. 暴露于新释放的氟吡禾草灵-苄基除草剂的黑线鲈的肝脏毒性和遗传毒性。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-15 DOI: 10.1007/s10646-025-02864-1

Noura Nabet, Elsayed A Khallaf, Alaa Alne-Na-Ei, Islam M El-Garawani, Rehab G Elgendy, Esraa Hanafy, Nasr Khalil, Heba M R Hathout

{"title":"The induced hepatotoxicity and genotoxicity in Oreochromis niloticus exposed to a newly released florpyrauxifen-benzyl herbicide.","authors":"Noura Nabet, Elsayed A Khallaf, Alaa Alne-Na-Ei, Islam M El-Garawani, Rehab G Elgendy, Esraa Hanafy, Nasr Khalil, Heba M R Hathout","doi":"10.1007/s10646-025-02864-1","DOIUrl":"https://doi.org/10.1007/s10646-025-02864-1","url":null,"abstract":"The investigation of the toxic potential of a newly introduced herbicide, Florpyrauxifen-benzyl (FPX), on Nile tilapia (Oreochromis niloticus) was the aim of this study. For 96 h, the median lethal concentration (LC50) was assessed in fish juveniles using the Probit analysis following the exposure to five concentrations of FPX (2-3 ppm). For investigating some mechanisms of FPX toxicity, fish were allocated into three groups (0, 0.27 and 0.54 ppm of FPX) and the cut-off intervals of the exposure were at 7 and 15 days. Liver malondialdehyde (MDA) and reduced glutathione (GSH) levels were assessed. In addition, superoxide dismutase (SOD) and catalase (CAT) were evaluated at both of transcriptional and enzymatic activity levels. Histopathological effects on the liver and erythrocytic nuclear abnormalities (ENAs) were monitored too. The 96h-LC50 was found to be 2.61 ppm, revealing the toxic potential of the FPX on Nile tilapia. Concentrations of FPX induced oxidative stress in fish by altering activities of antioxidant enzymes and their transcripts. The genotoxic effect of FPX was evidenced by a significant (P < 0.05) increase in micronuclei (MNs) and ENA frequencies. Significant liver histopathological alterations were observed at both FPX concentrations, with the highest effects at a concentration of 0.54 ppm FPX. Results suggest that FPX may exert oxidative, genotoxic, and histopathological effects on non-targeted species such as Nile tilapia if it is used improperly. Although fish could be used as an indicator for toxic materials in the aquatic habitat, future studies on other organisms, FPX concentrations or durations are recommended.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633453","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of metallothionein gene in Cd and Pb detoxification in Chironomus kiiensis. 金属硫蛋白基因在kiiensis Cd和Pb解毒中的作用。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-13 DOI: 10.1007/s10646-025-02865-0

Liqiong Yan, Chunmiao Sun, Lili Sun, Chuanwang Cao

{"title":"Role of metallothionein gene in Cd and Pb detoxification in Chironomus kiiensis.","authors":"Liqiong Yan, Chunmiao Sun, Lili Sun, Chuanwang Cao","doi":"10.1007/s10646-025-02865-0","DOIUrl":"https://doi.org/10.1007/s10646-025-02865-0","url":null,"abstract":"Heavy metal pollution in the aquatic environment is a growing concern. Consequently, it is crucial to promptly and accurately assess the level of contamination. Metallothionein (MT), an omnipresent protein, plays a pivotal role in regulating metal balance and detoxifying harmful substances. This study focused on CkMT, the metallothionein gene from the aquatic insect Chironomus kiiensis. The full-length cDNA of the CkMT gene was identified and cloned from C. kiiensis, revealing a 138-base-pair sequence that encodes 45 amino acids, with the CkMT protein being rich in cysteine. The CkMT was expressed throughout all developmental stages and in all tissues, as determined by quantitative reverse transcription PCR (qRT-PCR), with the highest expression observed in the larval stage and the midgut. Exposure to different concentrations of heavy metals (Cd, Pb, or a mixture of both) significantly induced the expression of CkMT. The functions of CkMT in C. kiiensis were investigated using RNA interference (RNAi). This knockdown resulted in increased larval mortality and decreased pupation and eclosion rates. Additionally, the overexpression of recombinant CkMT in Escherichia coli enhanced tolerance to Cd and Pb. Together, this study reveals that CkMT plays an important physiological role in the growth and development of C. kiiensis and suggests that CkMT is involved in the detoxification and tolerance of Cd and Pb in C. kiiensis. Furthermore, these findings highlight CkMT's potential as a valuable biomarker for monitoring Cd and Pb contamination in aquatic ecosystems.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143623982","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of plasticiser exposure on oyster Crassostrea (Magallana) saidii: assessing oxidative stress and biomarker responses. 增塑剂暴露对牡蛎长牡蛎（Magallana） saidii的影响：评估氧化应激和生物标志物反应

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-03-12 DOI: 10.1007/s10646-025-02866-z

Siti Afida Ishak, Ahmad Zaharin Aris, Mei Ching Law, Ley Juen Looi, Murni Marlina Abd Karim

{"title":"Impact of plasticiser exposure on oyster Crassostrea (Magallana) saidii: assessing oxidative stress and biomarker responses.","authors":"Siti Afida Ishak, Ahmad Zaharin Aris, Mei Ching Law, Ley Juen Looi, Murni Marlina Abd Karim","doi":"10.1007/s10646-025-02866-z","DOIUrl":"https://doi.org/10.1007/s10646-025-02866-z","url":null,"abstract":"Plasticisers are prevalent chemical contaminants that leach from plastics into aquatic ecosystems, posing potential risks to marine life. This study investigated the effects of alternative plasticisers [epoxidised methyl oleate (EMO), di-(2-ethylhexyl) adipate (DEHA), and diisononyl phthalate (DINP)] at 100 µg/L in oysters Crassostrea (Magallana) saidii over 21 days under controlled laboratory conditions. This study focused on changes in body weight, antioxidant enzyme activities such as superoxide dismutase (SOD) and catalase (CAT), non-enzymatic antioxidant reduced glutathione (GSH), lipid peroxidation (malondialdehyde (MDA) levels) after plasticisers exposure for 7, 14 and 21 days. The results indicated a decline in body weight in DINP-exposed oysters, indicating metabolic alterations. DEHA and DINP showed a pronounced increase in SOD activity at the end of the experiment, indicating elevated oxidative stress. CAT activity increased with EMO exposure, but decreased in oysters treated with DEHA and DINP. GSH levels were inversely proportional to CAT activity. Oysters exposed to DEHA and DINP exhibited higher MDA levels, indicating oxidative lipid damage associated with these plasticisers. Multi-biomarker data were integrated using the Integrated Biomarker Response (IBR) index, which ranked the plasticisers' oxidative stress potential as DEHA > DINP > EMO. The IBR analysis also suggested distinct modes of action among the plasticisers and provided insights into their toxicity mechanisms. Notably, EMO exhibited lower toxicity compared to DEHA and DINP, supporting its potential as a more friendly alternative to conventional plasticisers, albeit not exempt from toxic effects. These insights underscore the importance of environmental risk assessments in the future development of safer chemical alternatives.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143613995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0