Ecotoxicology最新文献

{"title":"Growth regulator herbicides and adjuvants effects on soil microbial activity.","authors":"Raphael Mereb Negrisoli, Diego Munhoz Gomes, Mayara Bolognesi, Renato Nunes Costa, Alysson Dias Dalmas, Robinson Antonio Pitelli, Caio Antonio Carbonari, Edivaldo Domingues Velini","doi":"10.1007/s10646-025-02936-2","DOIUrl":"10.1007/s10646-025-02936-2","url":null,"abstract":"<p><p>Soil microorganisms are vital for maintaining ecosystem functioning and play a central role in the degradation of herbicides. However, the specific effects of herbicides and their formulations on soil microbial activity remain insufficiently characterized, particularly in non-agricultural environments. This study evaluated the impact of five herbicides-Arsenal® (imazapyr), Dominum® (aminopyralid, and fluroxypyr), Pluris® (triclopyr, picloram, and aminopyralid), Garlon® (tricloplyr), and Glyphosate® (glyphosate)-and five adjuvants-Agral, Assist, Aureo, Silwet, and VegetOil-on microbial activity, using global heterotrophic soil respiration as a functional indicator. Soil samples from a non-agricultural area were incubated under controlled laboratory conditions for 28 days. Herbicides were applied at three dosages, while adjuvants were tested at label-recommended concentrations. Additionally, herbicide degradation was quantified using liquid chromatography. Results showed no significant differences in microbial respiration between treatments and untreated control, regardless of application rate. However, a modest increase in respiration was observed in soils treated with certain herbicides, notably Pluris® (19%) and Dominum® (23%), suggesting potential microbial stimulation. Adjuvants also exhibited no inhibitory effects, with Assist and VegetOil slightly enhancing respiration. Chromatographic analysis confirmed rapid degradation of all active ingredients, exceeding 80% within 28 days, with fluroxypyr degrading most extensively (97%). These findings indicate that, under the tested conditions, neither herbicides nor adjuvants adversely affect soil microbial respiration. Nevertheless, the observed variability highlights the need for field-based and long-term studies, particularly in integrated vegetation management scenarios, to better understand potential ecological implications and guide sustainable herbicide use in sensitive environments.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1537-1544"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrated biomarker response in common carp fingerlings exposed to neonicotinoid insecticide imidacloprid.","authors":"Hemanta Pokhrel, Raktim Sarmah, Darshana Sharma, Lucy Ingtipi, Naznin Ahmed, Sarada Kanta Bhagabati, Rajdeep Dutta, Arnab Narayan Patowary, Simanku Borah, Utpal Kumar Das, Debojit Dekari, Biswajyoti Bordoloi","doi":"10.1007/s10646-025-02935-3","DOIUrl":"10.1007/s10646-025-02935-3","url":null,"abstract":"<p><p>Imidacloprid (IMI) is a systemic insecticide classified as a neonicotinoid, which targets the central nervous system of insects. This insecticide is commonly used to protect crops from sucking pests like ticks, whiteflies, plant hoppers, and leafhoppers. There are reports of IMI having highly toxic consequences on non-targeted organisms like bees, humans, and aquatic animals. However, information regarding adverse effects of long-term exposure of different commercial products containing IMI as an active compound on non-targeted animals is very scanty. Therefore, current research effort aims to determine toxicity effects of commercial-grade Premise, 30.50%, Suspension Concentrate (SC) containing IMI as an active compound on freshwater experimental fish Cyprinus carpio using an integrated biomarker approach. Fish were semi-statically exposed to 17.36, 20.38, and 26.04 mg/L of IMI, which corresponds to 1/12, 1/10, and 1/8 of 96 h Lethal Concentration (LC₅₀ i.e. 208.3 mg/L) for 28 days. Results showed significant changes in haemato-immunological, serum biochemicals, and antioxidant enzymes upon 28 days of exposure. IMI exposure induced ROS (Reactive Oxygen Species) production, increased malonaldehyde (MDA) content in liver and gill tissues and subsequently reduced acetylcholinesterase (AChE) activity in brain tissue. Moreover, assessment through micronuclei (MNi) test was suggestive that the tested product is genotoxic, which was evident through the induction of significant numbers of micronuclei formation in erythrocyte cells of the test organisms. From the present study, it is obvious that the commercial formulation of IMI, Premise, can also act as a potential immunosuppressor and oxidative stress enhancer and can trigger probable neurotoxic and genotoxic effects that may result in physiological imbalances. Thus, it might become imperative to focus the toxicity studies not only on analytical grade but also on commercial products containing IMI as an active compound in non-targeted organisms. The study also underscores the importance of sustainable pest management practices to protect non-target species and maintain ecosystem balance, ultimately safeguarding public health and promoting environmental conservation.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1516-1536"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648846","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microplastic contamination worsens the ecotoxicity of chlorpyrifos to cladoceran Ceriodaphnia cornuta (Sars, 1885) and Echinisca triserialis (Brady, 1886).","authors":"Kumar Rajan, Devesh Kumar Yadav, Ram Kumar","doi":"10.1007/s10646-025-02909-5","DOIUrl":"10.1007/s10646-025-02909-5","url":null,"abstract":"<p><p>The presence of microplastics (MPs) along with agrochemicals is being widely reported from lakes, ponds, and rivers. Microplastic (MP) in association with agrochemicals could have synergistic or antagonistic effects on non-target aquatic organisms and pose ecological risks. The present study explored the combined effects of MP, the insecticide chlorpyrifos (CPF) and MP preconditioned with CPF (MP^^CPF) on two cladocerans, Ceriodaphnia cornuta, and Echinisca triserialis in short-term and long-term laboratory bioassay tests. The experimental protocol included an acute bioassay at five different concentrations of MP (25, 40, 100, 200, and 500 particles mL^-1), CPF (0.01, 0.05, 0.1, 0.5, and 1 µgL^-1) and MP^^CPF. Whereas, CPF (0.01 µg L^-1), MP (25 particles mL^-1), and MP^^CPF in 0.01 µg L^-1 of CPF were selected for the chronic bioassay. Upon exposure to CPF, C. cornuta and E. triserialis displayed a dose-dependent mortality pattern with a 48 h LC₅₀ value of 0.06 µgL^-1_. No mortality was observed in the MP only treatment, but when MPs were preconditioned with CPF, the 48 h LC₅₀ value was 0.02 µgL^-1. Chronic exposure to MP, CPF, or MP^^CPF resulted in reduced survival and reproductive output in both the cladocerans. However, C. cornuta was more vulnerable than E. triserialis. A significant delay in age at first reproduction and shorter generation time were observed in the presence of MP^^CPF, suggesting MP-mediated enhanced toxicity of CPF, wherein CPF could have accumulated onto the MP surface, thus, intensifying its toxicity. The enhanced toxicity of organic pollutants by MPs in aquatic environments especially in pelagic organisms is a matter of concern.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1384-1396"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552603","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of toxic effects of a triazole fungicide, difenoconazole in a freshwater fish model.","authors":"Arpita Ray, Debojit Dutta, Aritri Sarkar, Min Bahadur","doi":"10.1007/s10646-025-02926-4","DOIUrl":"10.1007/s10646-025-02926-4","url":null,"abstract":"<p><p>Difenoconazole, a triazole fungicide, is widely used to control fungal infections in agriculture. Due to surface run-off, waterbodies are contaminated by difenoconazole that may cause detrimental effects to non-target aquatic organisms. This study was designed to determine the toxic impacts of difenoconazole on a fish, Pethia conchonius, from the river Teesta using histopathological, biochemical and molecular biomarkers. The 96h-LC₅₀ of 1.886 mg/L for difenoconazole was determined. Based on the 96 h-LC₅₀, three sub-lethal concentrations of difenoconazole, 0.037 mg/L, 0.188 mg/L and 0.377 mg/L, were selected. Histopathological study of the gills showed epithelial lifting, lamellar fusion, curling of secondary lamellae, hypertrophy, aneurysm and necrosis. DNA damage in the exposed groups was significantly higher than in the control, with increasing concentrations and duration of exposure, with a maximum increase of 73% in the Tail DNA. A significant decrease of almost 2-5 times in both catalase (CAT) and superoxide dismutase (SOD) activity along with a 3-5 fold reduction in cat and sod expression was noted in the gills and liver compared to the control in a dose and time-dependent manner. Therefore, this study confirms that difenoconazole adversely affects Pethia conchonius at cellular, enzymatic and DNA levels.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1368-1383"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biological Indices as Markers of the Health of Cirrhinus mrigala under the Stress of Microplastics and Metal Nanoparticles.","authors":"Megha Andotra, Simran Sharma, Arvinder Kaur","doi":"10.1007/s10646-025-02940-6","DOIUrl":"10.1007/s10646-025-02940-6","url":null,"abstract":"<p><p>Coexistence of microplastics and nanoparticles is an emerging concern for environmentalists. This study highlights the individual and combined toxicities of environmentally relevant concentrations of two particle sizes of low-density polyethylene microplastic [LDPE: 150-250 µm (M1) and < 150 µm (M2)] and Predicted No Effect Concentration [PNEC: 2.95 mg/L, 1/100 of 96 h LC₅₀ {295.319 (253.533-333.814) mg/L}] of nickel oxide nanoparticles (NiO NPs: N) on the well-being of a food fish, Cirrhinus mrigala. Length-weight relationship, Fulton Condition Factor (FCF), Relative Condition Factor (RCF), Hepatosomatic Index (HSI), Gastrosomatic index (GaSI), along with behavioural and morphological alterations, were recorded monthly during an exposure and recovery period of 60 days each. The biological indices declined significantly over the control (p < 0.001) in treatments. FCF (1.65 ± 0.05) and RCF (0.83 ± 0.03) were minimum in M2N after 60 days of exposure, but in M1N after 60 days of recovery period (1.34 ± 0.045 and 0.678 ± 0.03, respectively). Exposure and recovery values of b, HSI and GaSI were lowest in M1N. Abnormal swimming, distressed hitting against the walls, copious mucus secretion, haemorrhage, darkening of skin, clogging of intestine and feed avoidance seem to have reduced energy allocation and well-being, causing allometric growth in treatments. Minimum changes in N, cataract and exophthalmia in M2 and tumour formation in M2N clearly indicate that MPs and NPs altered behaviour and bioavailability of each other. Their coexistence in natural waters might pose a direct threat to organisms and hint at developing regulatory strategies for the discharge of microplastics and nanoparticles.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1606-1623"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First study of heavy metals analysis in hair and oxidative status of European Otters (Lutra lutra) from Southwestern Europe.","authors":"Javier García-Muñoz, David Fernández Casado, Ángel Portillo-Moreno, María Del Prado Míguez-Santiyán, Francisco Soler Rodríguez, Ana López-Beceiro, Luis Eusebio Fidalgo, Salomé Martínez-Morcillo, Marcos Pérez-López","doi":"10.1007/s10646-025-02911-x","DOIUrl":"10.1007/s10646-025-02911-x","url":null,"abstract":"<p><p>Heavy metal(loid)s are continuously released into semi-aquatic ecosystems. This poses a potential threat to wildlife, such as the European otter (Lutra lutra) whose population has been gradually declining. Non-invasive sampling (e.g., hair samples) offers a valuable approach to assess pollutant exposure in otters without harm. In this study, we quantified As, Cd, Hg, Pb, and Zn concentrations in the hair, liver, and kidney of European otters from NW Spain, with the aim of validating the effectiveness of hair as a non-invasive biomonitoring tool by comparing it with internal organ concentrations. The correlation between metal concentrations, age, sex, and habitat, as well as a battery of oxidative stress biomarkers (catalase, glutathione reductase, glutathione S-transferase and malondialdehyde production), were also assessed. Tissues from 28 otters were analyzed and metal concentrations were quantified by inductively coupled plasma mass spectrometry. Oxidative stress biomarkers, including antioxidant enzymes and lipid peroxidation, were determined in the liver and kidney by spectrophotometric methods. Significantly higher Hg concentrations were found in otter hair compared to liver and kidney, particularly in areas with local pollution sources. The rest of the heavy metal(loid)s were recorded at lower concentrations. Positive correlations were observed between Hg and As levels in hair and the liver and kidney. Statistically significant differences in Hg, Cd and Pb concentrations were found between adults and juveniles, as well as between males and females from coastal areas. Moreover, the correlations between heavy metal(loid)s and oxidative stress biomarkers reflected the physiological responses of individuals exposed to these pollutants. The present study is the first to quantify hair metal levels and oxidative status in the European otter from SW Europe. According to our findings, hair demonstrated its suitability as a non-invasive biomonitoring tool for assessing internal Hg and As concentrations, and could be considered in future long-term wildlife biomonitoring programs.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1351-1367"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476393/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A paired analysis of mercury among non-invasive tissues in Mexican free-tailed bats (Tadarida brasiliensis) to inform conservation monitoring.","authors":"Molly C Simonis, Kimberlee Whitmore, Kristin E Dyer, Meagan Allira, Bret Demory, Matthew M Chumchal, Daniel J Becker","doi":"10.1007/s10646-025-02928-2","DOIUrl":"10.1007/s10646-025-02928-2","url":null,"abstract":"<p><p>Contaminants can harm wildlife. However, measuring wildlife exposure to contaminants can be challenging due to accessibility of species and/or sampling tissue matrices needed to assess wildlife health risks. For example, in bats and other taxa that use roosts, collecting feces under colonies minimizes disturbance to species of conservation concern, but fecal contaminant concentrations may not directly correlate with tissue contaminant concentrations. Thus, there is a need for quantifying contaminant exposure relationships between sample matrices for initial risk assessments to address wildlife health and conservation needs. Our goal was to assess the relationship between fecal and fur total mercury (THg) concentrations. We collected paired feces and fur samples (n = 48) from Mexican free-tailed bats (Tadarida brasiliensis) in summer 2023 in western Oklahoma at a maternity roost. At the individual level, we found no correlation between fecal and fur THg. However, at the population level, fur THg concentrations were on average 6.06-times greater than fecal THg concentrations. We conclude that although fecal THg cannot serve as a proxy of individual bat fur THg, population-level differences could be used cautiously to estimate mean fur THg concentrations from under-roost feces and motivate individual-level sampling to assess health impacts. We encourage continued research across other insectivorous bat species and sites for determining THg relationships across tissues and initial risk assessments with minimal disturbance to species of conservation concern when a contaminant point source is not yet known.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1637-1644"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476295/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539562","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioaccumulation pattern of heavy metals in Avicennia marina at Visakhapatnam and Coringa Mangroves in India.","authors":"Anand Raju Kambala, Ramakrishna Chintala, Srinivas Reka","doi":"10.1007/s10646-025-02932-6","DOIUrl":"10.1007/s10646-025-02932-6","url":null,"abstract":"<p><p>This study explores the impact of heavy metal accumulation on Avicennia marina's physiological and anatomical aspects, focusing on its capacity for metal uptake and tolerance. Conducted across the Visakhapatnam Entrance Channel (VEC) field, Control Coringa mangroves, and controlled ex-situ greenhouse environments, the study examines the accumulation patterns of chromium (Cr), lead (Pb), and cadmium (Cd). The Potential Ecological Risk Index (RI) indicated that Cd posed a very high risk, with Cr and Pb also showing significant risks. The potential ecological risk coefficient Eir consistently placed Cd in the high-risk category, with other metals generally in low to moderate-risk categories. Physiological changes in plant tissues were analyzed using a fluorescence microscope, and higher metal concentrations were assessed with Inductively Coupled Plasma Mass Spectrometry (ICP-MS). The Bioconcentration Factor (BCF) and Translocation Factor (TF) were calculated to evaluate metal accumulation and translocation efficiency. In VEC, significant anatomical changes in Avicennia marina included moist leaves, expanded mesophyll areas, and thick cuticles with heavy metal deposits, especially in high metal concentrations. The region's pollution, driven by port activities and nearby industries, elevated heavy metal levels in sediments. Cd was identified as a very high-risk element at all stations. Comparative analysis with the Control Coringa mangroves indicated potential variations in metal accumulation strategies between the two regions within the same species. Anatomical changes in the VEC were more pronounced than fewer disruptions in Coringa mangroves. The findings highlight Avicennia marina's potential as a bioindicator species, reinforcing its ecological value in monitoring and managing pollution stress in coastal environments.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1563-1579"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing alkaline battery waste toxicity in Nile tilapia (Oreochromis niloticus): integrating physiological biomarker analysis with molecular docking insights.","authors":"Ahmad Waheed, Habiba Zafar, Hina Naz, Jabbir Ali Khan, Samra Shafqat, Muhammad Saleem Khan, Muhammad Wajid","doi":"10.1007/s10646-025-02939-z","DOIUrl":"10.1007/s10646-025-02939-z","url":null,"abstract":"<p><p>The widespread disposal of alkaline battery waste (ABW) poses significant environmental risks, particularly in aquatic ecosystems where heavy metals can accumulate and disrupt biological functions. This study evaluates the acute toxicity and sub-lethal effects of ABW exposure on Nile tilapia (Oreochromis niloticus), a key species in aquaculture and freshwater food chains. The 96-h LC₅₀ of ABW for Nile tilapia was determined to be 25.64 mg/L. Experimental fish were exposed to sub-lethal concentrations (10 and 40% LC₅₀) of ABW for 30 days, and multiple physiological and biochemical biomarkers were assessed. Growth performance parameters, including weight gain (WG) and specific growth rate (SGR), were significantly reduced in exposed groups. Elevated cortisol and blood glucose levels indicated heightened physiological stress, while liver function enzymes (alanine amino transferase (ALT) and aspartate aminotransferase (AST)) activity exhibited significant increases, reflecting hepatic impairment. Histopathological analyses of liver, gill, and muscle tissues revealed necrosis, hemorrhage, and myolysis, indicative of tissue damage due to ABW exposure. Molecular docking studies further demonstrated potential interactions of ZnO and MnO₂ with antioxidant enzymes (Superoxide dismutase (SOD), glutathione S-transferase (GST), and catalase (CAT)), suggesting oxidative stress as a contributing factor to observed toxic effects. These findings highlight the potential environmental hazards of ABW and emphasize the urgent need for proper waste management strategies to mitigate aquatic ecosystem contamination.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1545-1562"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological and cellular responses of Manila clam Ruditapes philippinarum exposed to different shapes and sizes of polyethylene terephthalate microplastics.","authors":"Hyeonji Nam, Jinyoung Song, Yooeun Chae, Jin Soo Choi, June-Woo Park","doi":"10.1007/s10646-025-02930-8","DOIUrl":"10.1007/s10646-025-02930-8","url":null,"abstract":"<p><p>Microplastics (MPs) are ubiquitous in marine environments and have become a major source of environmental pollution. Although fragmented and fibrous MPs are the most abundant shapes in marine environment, studies on shape- and size-dependent MP toxicity in marine benthic bivalves remain limited. In this study, we aimed to evaluate the chronic effects of different shapes and sizes of polyethylene terephthalate (PET) MPs on Manila clam Ruditapes philippinarum, and investigate their physiological and cellular responses. The mortality of R. philippinarum showed no changes at all concentrations of fragmented and fibrous MPs. The respiration rate of R. philippinarum induced by large fragmented MPs was recovered to the control level at 6 h, however, fibrous MPs significantly decreased compared to the control. In particular, fibrous MPs significantly increased and decreased filtration rate and lysosomal membrane stability, respectively, whereas the fragmented MPs showed no significant differences. These results enhance our understanding of the potential toxicological risks posed by MPs of various shapes and sizes to benthic organisms in marine environment.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1463-1475"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144564684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}