Ecotoxicology最新文献

Quantification of soil microbial functional genes as potential new method in environmental risk assessment of pesticides. 土壤微生物功能基因定量分析可作为农药环境风险评价的新方法。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-27 DOI: 10.1007/s10646-025-02920-w

Fabian Stache, Franziska Ditterich, Zuzana Hochmanová, Jakub Hofman, Christian Poll, Ellen Kandeler

{"title":"Quantification of soil microbial functional genes as potential new method in environmental risk assessment of pesticides.","authors":"Fabian Stache, Franziska Ditterich, Zuzana Hochmanová, Jakub Hofman, Christian Poll, Ellen Kandeler","doi":"10.1007/s10646-025-02920-w","DOIUrl":"https://doi.org/10.1007/s10646-025-02920-w","url":null,"abstract":"Pesticides can have adverse effects on soil microorganisms, but they are underrepresented in the currently required OECD 216 test for environmental risk assessment of plant protection products (PPP). The guideline monitors soil microbial nitrogen transformation over 28 days, potentially missing long-term effects of persistent pesticides. Additionally, nitrate alone may be not sensitive enough to detect disruptions in microbial functions. We investigated whether functional gene analysis could provide a more sensitive bioindicator of pesticide impact. To compare this method with the standard test, we conducted a microcosm experiment following the OECD 216 experimental setup. To capture long-term effects beyond the typical test period, we extended the incubation duration to 56 days. Four different concentrations of the persistent fungicide boscalid were added based on predicted environmental concentration. We also assessed microbial responses to fungicide exposure by measuring classical soil microbial parameters. According to the standard test, boscalid had no harmful long-term effects on soil microbiota. In contrast, our analysis of functional genes found an overall reduction in the acid phosphatase-encoding phoN gene abundance on Day 56, and correspondingly, in acid phosphatase activity in the highest fungicide treatment. Simultaneously, we observed a tendency towards lower fungal abundance based on measured copy numbers of an ITS region of nuclear ribosomal DNA (rDNA) and increased cumulative CO2 production. These results indicate a fungicide-related response of the microbial community and impaired microbial phosphorus cycling. Extending the experimental period to 56 days revealed long-term effects that would have otherwise been undetected under the typical 28-day test duration.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505105","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chronic exposure to diquat-based herbicide induces morphological, behavioral, and growth alterations in Physalaemus cuvieri tadpoles. 长期暴露于双氯菊酯类除草剂可诱导蝌蚪形态、行为和生长改变。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-27 DOI: 10.1007/s10646-025-02927-3

Diana Paula Giacomel, Guilherme Felicioni, Bruna Macedo Simoes Sergio, Aline Pompermaier, Wagner Antonio Tamagno, Paulo Afonso Hartmann, Marilia Hartmann

{"title":"Chronic exposure to diquat-based herbicide induces morphological, behavioral, and growth alterations in Physalaemus cuvieri tadpoles.","authors":"Diana Paula Giacomel, Guilherme Felicioni, Bruna Macedo Simoes Sergio, Aline Pompermaier, Wagner Antonio Tamagno, Paulo Afonso Hartmann, Marilia Hartmann","doi":"10.1007/s10646-025-02927-3","DOIUrl":"https://doi.org/10.1007/s10646-025-02927-3","url":null,"abstract":"Pesticides pose a serious threat to non-target organisms and are classified as key contributors to amphibian population decline. Amphibians, known for their sensitivity to environmental changes, serve as valuable bioindicators of environmental health. In this study, we assessed the toxicity of a diquat-based herbicide (DBH) on the bioindicator species Physalaemus cuvieri. Tadpoles were exposed to a broad toxicity gradient of DBH (20, 50, 250, 500, 1000, and 1500 µg L-1) for 336 h. Survival, body mass index (BMI), scaled mass index (SMI), malformations, and swimming activity were evaluated. Exposure to 1000 and 1500 µg L-1 significantly reduced survival. Interestingly, concentrations of 20, 50, 1000, and 1500 µg L-1 led to increases in BMI and SMI. Malformations and alterations in swimming behavior were detected at all concentrations. These findings demonstrate that DBH is highly toxic to P. cuvieri tadpoles, severely impairing their survival, physiology, and behavior. These results have significant environmental implications, as tadpoles play a crucial role in aquatic ecosystems, and this sensitivity to DBH can trigger imbalances in trophic dynamics. Furthermore, amphibians are bioindicators, and the impacts observed here reinforce the need for rigorous monitoring of potentially toxic chemicals in aquatic ecosystems to preserve biodiversity, especially among non-target species.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Alteration of growth, hematology, histopathology of tissues and immune-antioxidant genes expression in Nile tilapia following co-exposure of hexavalent chromium and polyamide microplastics. 六价铬和聚酰胺微塑料共同暴露对尼罗罗非鱼生长、血液学、组织病理学和免疫抗氧化基因表达的影响

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-26 DOI: 10.1007/s10646-025-02917-5

Naimul Islam, Sheik Istiak Md Shahriar, Shifat Ara Noor, Bilal Ahamad Paray, Md Mahiuddin Zahangir, Md Shahjahan

{"title":"Alteration of growth, hematology, histopathology of tissues and immune-antioxidant genes expression in Nile tilapia following co-exposure of hexavalent chromium and polyamide microplastics.","authors":"Naimul Islam, Sheik Istiak Md Shahriar, Shifat Ara Noor, Bilal Ahamad Paray, Md Mahiuddin Zahangir, Md Shahjahan","doi":"10.1007/s10646-025-02917-5","DOIUrl":"https://doi.org/10.1007/s10646-025-02917-5","url":null,"abstract":"Chromium (Cr) and microplastics (MP) pollution in aquatic environments is increasing, and it is hypothesized that the combined effects of these two pollutants have variable impacts on the physiology of aquatic organisms. An experiment was conducted to evaluate the combined effects of these contaminants on survival, growth, hematology, intestinal and liver histology, oxidative stress, and immunity of Nile tilapia (Oreochromis niloticus). Fish were exposed to T1 (10 mg/L polyamide microplastic; PA-MP), T2 (8 mg/L hexavalent chromium; Cr-VI), T3 (8 mg/L Cr-VI + 10 mg PA-MP) with a control group in triplicates. After 42 days of exposure, it was observed that the ingestion of microplastics in the gastrointestinal tract (GIT), feed conversion ratio (FCR) and mortality were highest in T3 with the co-exposure of Cr-VI with PA-MP. There was an increasing trend in blood glucose concentration and a decreasing trend in hemoglobin concentration observed from T1 to T3. Nuclear and cellular abnormalities became more frequent and histological observation was also aggravated in T3. The relative mRNA expression of antioxidant genes like SOD (superoxide dismutase) and CAT (catalase) was significantly upregulated in T2 and T3 and the immune genes such as TNF-α (Tumor necrosis factor- α), IL-1β (Interleukin-1β) and IFN-γ (Interferon- γ) were also significantly upregulated in T2 and T3 with the exposure of Cr-VI alone and co-exposure of Cr-VI and PA-MP. Therefore, the combined exposure of Cr with PA-MP negatively impacted the overall physiology of Nile tilapia and, there was considerable evidence that polyamide microplastics worsen the overall toxic effects of hexavalent chromium in Nile tilapia.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144505152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Metal and metal-oxide nanoparticles inducing changes in reactive oxygen species levels and enzymes of oxidative stress: a review focused on daphnids. 金属和金属氧化物纳米颗粒诱导活性氧水平和氧化应激酶的变化：以水蚤为中心的综述。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-25 DOI: 10.1007/s10646-025-02907-7

Lucas Gonçalves Queiroz, Susana Inés Córdoba de Torresi

{"title":"Metal and metal-oxide nanoparticles inducing changes in reactive oxygen species levels and enzymes of oxidative stress: a review focused on daphnids.","authors":"Lucas Gonçalves Queiroz, Susana Inés Córdoba de Torresi","doi":"10.1007/s10646-025-02907-7","DOIUrl":"https://doi.org/10.1007/s10646-025-02907-7","url":null,"abstract":"In recent years, the number of publications on the effects of nanoparticles on freshwater organisms has increased. The Daphnia genus is widely used in ecotoxicological studies as a model organism for evaluating the environmental impact of nanomaterials. In this context, enzymatic biomarkers have been increasingly adopted to understand the potential of metallic nanoparticles (MNPs) to induce oxidative stress. The present paper aims to synthesize the current knowledge on oxidative stress responses in daphnids exposed to metallic and metal-oxide MNPs, with a particular focus on enzymatic biomarkers (SOD, CAT, GPx, GR and GST). Specifically, we aimed to identify patterns of enzymatic responses promoted by the exposure of Daphnia species to MNPs and highlight research deficits that need to be addressed in further studies. A literature survey was performed in April 2025. This survey found 322 studies, which were screened, resulting in 36 studies included in this review. Based on our literature survey, Daphnia magna is the most commonly used daphnid to evaluate oxidative stress promoted by MNPs. Titanium-based nanomaterials have been the most studied MNPs, followed by silver and zinc. We observed that the enzymatic activity pattern is not directly associated with the metallic composition of the nanoparticle. We discuss how the chemical composition can reflect the specific toxicity of MNPs, although environmental, abiotic, and physicochemical factors can have a greater influence. Enzymatic biomarkers provide valuable information on the extent and nature of the biological effects of exposure to metallic and metal-oxide nanoparticles.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of sunscreens on survival, reproduction, energy metabolism, and antioxidant system of brackish water flea Diaphanosoma celebensis. 防晒霜对苦咸水蚤生存、繁殖、能量代谢及抗氧化系统的影响。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-25 DOI: 10.1007/s10646-025-02906-8

Je-Won Yoo, Chaerin Park, Hyesung Lee, Youn-Ha Lee, Young-Mi Lee

{"title":"Effects of sunscreens on survival, reproduction, energy metabolism, and antioxidant system of brackish water flea Diaphanosoma celebensis.","authors":"Je-Won Yoo, Chaerin Park, Hyesung Lee, Youn-Ha Lee, Young-Mi Lee","doi":"10.1007/s10646-025-02906-8","DOIUrl":"https://doi.org/10.1007/s10646-025-02906-8","url":null,"abstract":"The increasing use of sunscreen to protect human skin from UV-A and UV-B is a great concern in the marine ecosystem. However, the toxicity of sunscreen products on marine biota is currently unclear. Thus, we investigated the toxic effects of four commercial sunscreens (A-D) selected according to the formulation on the survival, reproduction, energy metabolism, and antioxidant system of the brackish water flea Diaphanosoma celebensis. The 48 h median lethal concentrations (48-h LC50) of sunscreen extracts were determined as 57.22%, and 43.59% in product C and product D, respectively. At the environmentally relevant concentrations, product D disrupted reproduction and reduced body length. Although no significant differences in energy reserves were observed, AMPK genes were highly modulated in the solid products C and D. SOD activity was significantly increased in all experimental groups, and the expression of CAT was up-regulated in groups exposed to products C and D. Our results imply that commercial sunscreens have a formulation-dependent effect on reproductive toxicity by disrupting redox and energy homeostasis.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Exposure to a glyphosate-based herbicide does not alter maternal care and offspring quality in the European earwig. 暴露于草甘膦除草剂不改变母性护理和后代质量在欧洲蠼螋。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-25 DOI: 10.1007/s10646-025-02912-w

Laura Pasquier, Julie Groutsch, Maïlys Verger, Violette Wallart, Joël Meunier, Charlotte Lécureuil

{"title":"Exposure to a glyphosate-based herbicide does not alter maternal care and offspring quality in the European earwig.","authors":"Laura Pasquier, Julie Groutsch, Maïlys Verger, Violette Wallart, Joël Meunier, Charlotte Lécureuil","doi":"10.1007/s10646-025-02912-w","DOIUrl":"https://doi.org/10.1007/s10646-025-02912-w","url":null,"abstract":"Sublethal exposure to pesticides can affect the reproduction and population dynamics of many non-target organisms, such as insects. Among these pesticides, glyphosate-based herbicides (GBHs) were long thought to have no effect on insects because their active compounds can only affect plants and microorganisms. However, a growing body of evidence suggests that GBH can directly or indirectly alter a wide range of fitness-related traits in insects. In this study, we tested whether exposure to the GBH Roundup© affects maternal care behaviour and juvenile development, locomotion and immunity in the European earwig, an insect commonly found in vineyards and orchards. First, we exposed female earwigs to Roundup at concentrations ten times below, equal to and ten times above the normal application rate (NAR) and then measured the expression of maternal care in terms of egg collection, egg and juvenile care and defense. We also measured maternal self-grooming and locomotor activity, and the development time, weight and size of newly produced juveniles. In a second experiment, we exposed earwig juveniles to a control solution or to Roundup and then measured their locomotion, the expression of genes involved in their development (the juveniles hormone pathway), and their survival after exposure to a fungal pathogen. Overall, our results showed no significant effect of Roundup on any of the parameters measured. This finding suggests that direct exposure to a GBH formulation may not necessarily induce behavioural, physiological and developmental alteration in this species. It also calls for future studies to explore the underlying mechanisms behind this apparent lack of sensitivity. More generally, these results highlight the importance of assessing the impact of pesticide use and the factors driving potential resilience across a wide range of non-target organisms to ensure sustainable agricultural practices.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144495213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Side effects of insecticides used in soybean and corn on the egg parasitoid Telenomus remus (Hymenoptera: Scelionidae). 大豆和玉米用杀虫剂对卵寄生蜂小蜂（膜翅目：小蜂科）的副反应。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-24 DOI: 10.1007/s10646-025-02913-9

Vanessa Exteckoetter, Júlia Assunção de Castro Oliveira, Karolina Gomes de Figueiredo, Adeney de Freitas Bueno, Geraldo Andrade Carvalho

{"title":"Side effects of insecticides used in soybean and corn on the egg parasitoid Telenomus remus (Hymenoptera: Scelionidae).","authors":"Vanessa Exteckoetter, Júlia Assunção de Castro Oliveira, Karolina Gomes de Figueiredo, Adeney de Freitas Bueno, Geraldo Andrade Carvalho","doi":"10.1007/s10646-025-02913-9","DOIUrl":"https://doi.org/10.1007/s10646-025-02913-9","url":null,"abstract":"Spodoptera frugiperda (Lepidoptera: Noctuidae) is one of the main pests of corn and soybeans. Its control, usually done with insecticides, can reduce natural enemies and cause biological imbalances. One of these enemies is the egg parasitoid Telenomus remus (Hymenoptera: Scelionidae). The objective of this study was to evaluate the side effects of the insecticides chlorantraniliprole, indoxacarb, spinetoram, and chlorpyrifos, at the highest dosages recommended by the manufacturers to control S. frugiperda, aiming to integrate chemical and biological methods. Insecticides were applied to adult females of T. remus and eggs of S. frugiperda containing the parasitoid in its immature stages (egg-larval and pupa). The experiment was entirely randomized. Survival, parasitism, emergence, and sex ratio were evaluated. Chlorpyrifos reduced parasitism of females (F0) and emergence of parasitoids (F1) by 100% when applied to immature stages, and was classified as harmful by the IOBC. The other insecticides were selective at this stage. Spinetoram and chlorpyrifos were toxic to adult females (F0) exposed to residues, causing 100% mortality in less than 24 h. Chlorantraniliprole and indoxacarb were not toxic when applied directly to adult females (F0). Due to the low toxicity of chlorantraniliprole, spinetoram and indoxacarb for immature stages, and of indoxacarb and chlorantraniliprole for adults, these insecticides should be prioritized in the integrated management of S. frugiperda.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144483656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nitrate and phosphate additive toxicity to the Mexican salamander Ambystoma dumerilii and implications for water quality management. 硝酸盐和磷酸盐添加剂对墨西哥蝾螈的毒性及其对水质管理的影响。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-20 DOI: 10.1007/s10646-025-02915-7

María Angeles González-Vázquez, Rebeca Aneli Rueda-Jasso, Gordon R Craig

{"title":"Nitrate and phosphate additive toxicity to the Mexican salamander Ambystoma dumerilii and implications for water quality management.","authors":"María Angeles González-Vázquez, Rebeca Aneli Rueda-Jasso, Gordon R Craig","doi":"10.1007/s10646-025-02915-7","DOIUrl":"10.1007/s10646-025-02915-7","url":null,"abstract":"Salamanders are among the most threatened vertebrates due to chemical and habitat stressors. The Mexican salamander, Ambystoma dumerilii is endemic to Lake Pátzcuaro, Michoacán, Mexico and is exposed to nutrient runoff and discharges from surrounding agriculture and municipal waste. This study evaluated the toxicity of nitrate and phosphate singly and in mixtures to embryonic and the first-stage larval development of A. dumerilii to determine whether measured surface water concentrations comparable to those found in Lake Pátzcuaro pose a risk and whether Mexico's water quality standards are adequate to protect the species. Eggs and larvae of A. dumerilii were exposed for 26 days to nitrate and phosphate individually as well as to dilutions of a mixture based on their LC50 concentrations. The Probit determined LC50 for NO3-N was 887 mg/L and for PO4-P was 2015 mg/L. The LC50 for the mixture was 1.0 toxic unit (TU), while the EC50 for the hatching inhibition mixture was 0.26 TU. Effect thresholds were 0.1 and 0.04 TU respectively. Concentrations of nitrate and phosphate mixtures in selected Mexican surface waters were above the hatching inhibition threshold and the equivalent Mexican standards expressed as mixtures also exceeded this threshold. The toxicity responses to the mixtures suggest that nitrate and phosphate anions compete for the same sites and act in an additive manner. Nitrate and phosphate need to be managed as mixtures rather than singly to protect species with similar sensitivities to A. dumerilii. However, further research is needed to confirm these effects across other aquatic species.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Short-term effects of acrylamide exposure towards fatty acids' composition and histological features of the rayed trough-shell Mactra stultorum' branchial tissues. 丙烯酰胺暴露对透壳大鼠鳃组织脂肪酸组成及组织学特征的短期影响。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-20 DOI: 10.1007/s10646-025-02910-y

Wafa Trabelsi, Chaima Fouzai, Safa Bejaoui, Feriel Ghribi, Rym Baati, Nejla Soudani

{"title":"Short-term effects of acrylamide exposure towards fatty acids' composition and histological features of the rayed trough-shell Mactra stultorum' branchial tissues.","authors":"Wafa Trabelsi, Chaima Fouzai, Safa Bejaoui, Feriel Ghribi, Rym Baati, Nejla Soudani","doi":"10.1007/s10646-025-02910-y","DOIUrl":"10.1007/s10646-025-02910-y","url":null,"abstract":"Acrylamide (ACR) is a broad-spectrum water-soluble monomer used in polymer production. Through assorted pathways, such as wastewater offload, industrial effluents, and leaching from polyacrylamide grouting materials, ACR can reach aquatic environments and readily influence common organisms in coastal areas near urban or industrial zones, notably edible clams. The current study evaluated the ACR impact on the fatty acids (FA) composition in the rayed trough-shell Mactra stultorum gills. Bivalves were exposed to ACR-graded concentrations (5,10, and 20 mg/L) for 5 days. At the end of the trial, the gills' ACR burden exhibited significant increases reflecting its harmful influence. Our results showed that ACR promoted oxidative imbalance, highlighted by increased hydrogen peroxide (H2O2) levels. A considerable decrease in saturated fatty acids (SFA) in ACR-treated clams was recorded. In terms of n-6 (Omega 6) and n-3 (Omega 3) polyunsaturated fatty acids series, we noted a high induction in arachidonic (ARA, C20:4n-6) (and its precursor linoleic acid (LA, C18:2n-6)), eicosapentaenoic (EPA, C20:5n-3), and docosahexaenoic (DHA, C22:6n-3) acids level. The results showed a significant increase in the dienoic non-methylene-interrupted fatty acid (NMID, C22 :2) amounts in ACR-treated clams. While our findings revealed that this electrophile produced pronounced effects on the lipid fraction of M. stultorum gills, these results were further confirmed by the harmful histological anomalies. Our research outlines the urgency of further investigations into ACR-induced metabolic impacts to fully assess its long-term outcomes on aquatic ecosystems.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144332645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioaccumulation and sub-chronic toxicity of microplastic environmentally relevant concentrations in Etroplus suratensis brackish water fish. 微塑料环境相关浓度在咸淡水鱼体内的生物积累和亚慢性毒性。

IF 2.4 4区环境科学与生态学

Ecotoxicology Pub Date : 2025-06-19 DOI: 10.1007/s10646-025-02914-8

Bini C Das, Vineetha V P, Devika Pillai, Rejish Kumar V J

{"title":"Bioaccumulation and sub-chronic toxicity of microplastic environmentally relevant concentrations in Etroplus suratensis brackish water fish.","authors":"Bini C Das, Vineetha V P, Devika Pillai, Rejish Kumar V J","doi":"10.1007/s10646-025-02914-8","DOIUrl":"https://doi.org/10.1007/s10646-025-02914-8","url":null,"abstract":"Numerous ecosystem-based studies have explored microplastic pollution in brackish water environments. However, research on the bioaccumulation of microplastics in brackish water fish and their effects remains limited. The present study investigated the bioaccumulation and effects of polystyrene microplastics (PS-MPs) in juvenile brackish water fish, pearl spot (Etroplus suratensis). Fish were exposed to 0, 0.2, 2, and 4 mg/L of 1 µm-sized PS-MPs for 14 days. PS-MPs were found in the gastrointestinal tract, gills, liver, spleen, muscle, and brain, with the highest concentration in the intestine and the lowest in the brain. Exposure to PS-MPs led to elevated serum level of glucose, total protein, total cholesterol, serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic-pyruvic transaminase (SGPT), and alkaline phosphatase (ALP). Antioxidant parameters such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), and total antioxidant capacity (TAC) decreased, while malondialdehyde (MDA) level and protein carbonyl (PC) content increased. PS-MP exposure down-regulated hepatic expression of NRF2 and P53, increased cortisol levels, and up-regulated HSP70 gene expression in a dose-dependent manner. Additionally, PS-MPs down-regulated expression of IGF1 and CYP1A in the liver. This is the first comprehensive research that has revealed the extent to which PS-MPs accumulate in various tissues of brackish water fish species after being exposed to environmentally significant concentrations. It also demonstrates the associated toxicity in an array of antioxidant indicators.","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-06-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144324764","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

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