Ecotoxicology最新文献

{"title":"Acaricide resistance and possible underlying biochemical mechanisms in the two-spotted spider mite, Tetranychus urticae Koch, on cut flowers.","authors":"Sundaravadivel Sathiya Priya, Ettiappan Sumathi, Ramkumar Haran, Perumal Renukadevi, Marimuthu Murugan, Thirumalaiandi Ramasubramanian, K K Kumar, S P Thamarai Selvi, Sivakumar Kowsika","doi":"10.1007/s10646-025-02973-x","DOIUrl":"https://doi.org/10.1007/s10646-025-02973-x","url":null,"abstract":"","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145225250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Eco(geno)toxicologic effects of arsenic-contaminated tropical soils: plant bioassays via the microplate approach.","authors":"Ingrid Fernanda Santana Alvarenga, Graciele Lurdes Silveira, Guilherme Henrique Silva, Gabriel Caixeta Martins, Leonardo Mendes da Silva, Luiz Roberto Guimarães Guilherme, Larissa Fonseca Andrade-Vieira","doi":"10.1007/s10646-025-02974-w","DOIUrl":"https://doi.org/10.1007/s10646-025-02974-w","url":null,"abstract":"","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":""},"PeriodicalIF":2.7,"publicationDate":"2025-10-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145211792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tracking solutions to a persistent threat: spatial movement patterns reflect lead exposure in critically endangered California condors.","authors":"Varalika Jain, Christopher J W McClure, Chris N Parish, Timothy J Hauck, Petra Sumasgutner","doi":"10.1007/s10646-025-02921-9","DOIUrl":"10.1007/s10646-025-02921-9","url":null,"abstract":"<p><p>Lead contamination, an exclusively human-induced issue, poses a serious threat to the critically endangered California Condor (Gymnogyps californianus). Contamination occurs through condors' ingestion of lead ammunition residues embedded within the remains of shot animals. Detecting lead exposures typically requires resource-intensive and invasive interventions. Here, we explored a minimally invasive alternative, analyzing movement data from GPS-tagged condors in the 30-day period prior to when their blood lead levels were measured. We found spatial, but not temporal, differences in movement patterns. Lead-exposed condors traversed larger areas of the landscape, with ranges more concentrated in a previously identified high-risk zone, and shared space more extensively with one another than unexposed individuals. However, lead-exposed condors did not exhibit declining movement patterns through time when compared to unexposed birds, making movement-inferred post-exposure detection difficult. While GPS-telemetry is a useful tool in understanding condors' spatial patterns in relation to lead exposure, future research exploring how movement patterns can be used to detect, predict, and provide early warnings of at-risk condors may better inform targeted conservation efforts.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1476-1488"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Involvement of esterases in increased resistance to pirimiphos-methyl and bifenthrin in Sitophilus oryzae (Linnaeus, 1763).","authors":"L C Cabral, V Wakida, D R Moreira, A A S Gigliolli, A S Lapenta, C G M Souza","doi":"10.1007/s10646-025-02933-5","DOIUrl":"10.1007/s10646-025-02933-5","url":null,"abstract":"<p><p>Sitophilus oryzae (L.) is a cosmopolitan pest of stored grains, frequently controlled using organophosphates and pyrethroids. However, the continuous use of these insecticides may lead to resistance development. Thus, this study evaluated the evolution of S. oryzae resistance after three generations (F3) of artificial selection with pirimiphos-methyl and bifenthrin, and the persistence of acquired resistance after three additional generations without exposure (F6) to insecticides. Two experiments were conducted: the Continuous Exposure Bioassay (CEB), with exposure to sublethal doses, and the Generation Selection Bioassay (GSB), with more intense selective pressure. Esterase activity was analyzed by electrophoresis to investigate the involvement of these enzymes in resistance mechanisms. Samples were subjected to native PAGE, and esterase bands were visualized using α- and β-naphthyl acetate as substrates. The results showed a significant increase in resistance in both approaches, with evidence of cross-resistance between the insecticides. Isoenzymatic analysis revealed the involvement of esterases, particularly cholinesterase Est-1, whose relative activity was higher in the selected generations, suggesting its role in compound detoxification. Additionally, there was a slight reduction in the resistance ratio after three additional generations without exposure, although not statistically significant. These findings highlight the importance of monitoring enzymatic resistance mechanisms for more effective insecticide management and mitigating the impacts of resistance on pest control strategies.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1624-1636"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144642081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential biochemical responses of Cyprinus carpio after dietary and waterborne exposure to microplastics from polyethylene-based biodegradable and conventional bags.","authors":"Tamiris Rosso Storck, Jaíne Ames, Gabriel Qualhato, Marlon de Castro Vasconcelos, Andreli Lopes Piccoli, Thiago Lopes Rocha, Andreia Neves Fernandes, Barbara Clasen","doi":"10.1007/s10646-025-02937-1","DOIUrl":"10.1007/s10646-025-02937-1","url":null,"abstract":"<p><p>Microplastics (MPs) can interact and generate toxic effects on exposed organisms, such as fish. However, little is known about the effects of exposing fish to biodegradable PE-MPs, and how the form of exposure is related to toxicity. The current study aimed to evaluate the impact of dietary and waterborne exposure to four types of polyethylene MPs (PE-MPs) from biodegradable and conventional bags on common carp Cyprinus carpio. The toxicity of PE-MPs from biodegradable (PE-BIO), transparent (HDPE-1), black (PE-OXO), and gray (HDPE-2) bags was analyzed after 7 days of exposure by multiple biochemical biomarkers assessment, such as neurotoxicity, oxidative and nitrosative stress, and oxidative damage. The toxicity of waterborne exposure of fish to PE-MPs followed the order: PE-OXO>HDPE-2>PE-BIO>HDPE-1, while the dietary exposure was: HDPE-2>PE-BIO>HDPE-1>PE-OXO. Furthermore, according to IBRv2, the HDPE-2 and PE-BIO treatments of dietary exposure showed greater changes in biomarkers compared to the control. Lipid peroxidation levels were altered only in dietary exposure treatments, while CAT and GST activity was generally inhibited in both exposure pathways. The PE-BIO treatments showed significant differences in relation to conventional plastics, mainly in the nitric oxide (NO) content of the fish liver, which increased or decreased depending on the route of exposure. Therefore, this pioneering study emphasizes that the composition of PE-MPs and the route of exposure can generate different effects on C. carpio biomarkers. Furthermore, these results may indicate the effects of environmental contamination by MPs in a freshwater fish species.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1580-1596"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144658727","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of bisphenol A and S, on oxidative stress, neurotoxicity, and fatty acid composition in sea cucumber, Holothuria poli.","authors":"Maroua Jenzri, Zied Bouraoui, Hamadi Guerbej, Jamel Jebali, Tahar Gharred","doi":"10.1007/s10646-025-02925-5","DOIUrl":"10.1007/s10646-025-02925-5","url":null,"abstract":"<p><p>Bisphenols, recognized as emerging environmental pollutants, are widely detected in marine ecosystems, raising concerns about their potential toxicity to marine organisms. This study investigates the effects of bisphenol A (BPA) and bisphenol S (BPS), individually and in combination, on the biochemical responses of the sea cucumber Holothuria poli. Sea cucumbers (n = 60) were exposed to 200 µg/L BPA, BPS, or a combination of both for 12 days. The results indicated that exposure to BPA and BPS induced oxidative stress, evidenced by increased malondialdehyde (MDA) levels (p < 0.05) and elevated activities of glutathione S-transferase (GST) and catalase, along with enhanced glutathione levels (p < 0.05). A significant rise in acetylcholinesterase (AChE) activity (p < 0.05) suggested potential neurotoxic effects and disruptions in neurological functions in sea cucumbers. Additionally, BPA and BPA + BPS significantly increased alkaline phosphatase (ALP) activity (p < 0.05), indicating altered phosphatase metabolism. Changes in the fatty acid profile, including variations in docosahexaenoic acid (DHA), palmitic acid, myristic acid, palmitoleic acid, and linolenic acid levels, were observed, linked to oxidative stress and adaptive strategies to mitigate bisphenol toxicity. In conclusion, exposure to BPA and BPS induced oxidative stress, neurotoxicity, and altered fatty acid composition in H. poli. These findings suggest that sea cucumbers could serve as sensitive bioindicators for monitoring environmental contamination.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1447-1462"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144552602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Environmentally relevant concentrations of butachlor inhibited the development of the green toad (Bufotes viridis sitibundus) during the incubation period.","authors":"Alireza Pesarakloo, Zahra Zarei, Sayed Jamal Mirkamali, Milad Esmaeilbeigi","doi":"10.1007/s10646-025-02922-8","DOIUrl":"10.1007/s10646-025-02922-8","url":null,"abstract":"<p><p>Butachlor is one of the most widely used herbicides in agricultural areas throughout the world. Studies have measured the toxicity of butachlor in single life stages of amphibians, however, less attention has been paid to the impacts of this herbicide on various life stages. Therefore, we collected the eggs of the green toad Bufotes viridis sitibundus from a clean environment with no history of pesticides. We then exposed the collected eggs to environmentally relevant concentrations of butachlor (1.5, 1, 0.8, 0.6, 0.4, and 0.1 mg/L) and measured the growth, survival, and development of green toads during the incubation period. We also measured five different responses i.e., length at the beginning of metamorphosis (LBM), length at the formation of forelimb bud (LFF), length at the end of metamorphosis (LEM), weight at the beginning of metamorphosis (WBM), and weight at the end of metamorphosis (WEM) during the incubation period. The survival rate showed an indirect relationship with butachlor concentrations. The longest development duration was recorded for toads reared in the control (110 days), while the shortest duration (9 days) was observed in the highest butachlor concentration (i.e., 1.5 mg/L), with the highest mortality recorded in this treatment- all the eggs dying by days 11 and 9 after the start of incubation. We found a significant difference between the survival of toads in butachlor treatments and the control group (P < 0.05). We observed a significant difference between treatments and the control group in LBM, LFF, LEM, and WEM (P < 0.05), except WBM (P > 0.05). Our findings highlight that butachlor, at environmentally relevant concentrations, inhibited the development of the green toad and mitigated the survival of eggs and larvae, resulting in the unsuccessful completion of development before metamorphosis, a critical life stage.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1397-1405"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144539563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of multi-generational exposure to Fluorine-Free Foam (F3) alternatives on Daphnia magna tolerance.","authors":"Jack D Morehouse, Devin K Jones, Jason T Hoverman","doi":"10.1007/s10646-025-02938-0","DOIUrl":"10.1007/s10646-025-02938-0","url":null,"abstract":"<p><p>Per- and polyfluoroalkyl substances (PFAS) have historically been a key component in aqueous film-forming foams (AFFF) used in fire suppression. With the increasing emphasis on phasing out PFAS use due to health and environmental concerns, several new chemical technologies have been used to create fluorine-free foam (F3) alternatives. Recent research has demonstrated that these replacement formulations are more acutely toxic to aquatic species than the traditional PFAS-containing AFFF. Given their relatively high acute toxicity, prolonged exposure to the formulations could lead to adaptive responses (i.e., evolved tolerance) in exposed populations. In this study, we examined the effects of chronic exposure to six F3 alternatives and one PFAS-containing AFFF on tolerance to the formulations in the water flea Daphnia magna. Following an 84-day exposure to different concentrations of each formulation, we used a series of laboratory lethal concentration (LC₅₀) tests on a subset of populations to examine the potential change in tolerance. We found that chronic exposure to three formulations led to a change in tolerance in exposed populations as compared to those with no prior exposure; two populations displayed increased tolerance while one showed decreased tolerance. This work is the first to examine evolved responses to F3 alternatives. Our results highlight the frequently overlooked evolutionary effects of contaminant exposure and the broader need to understand the effects of F3 alternatives on the environment.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1597-1605"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12476401/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144648847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating pesticide-induced toxicity in Cyprinus carpio using hemato-biochemical biomarkers.","authors":"Muhammad Yaseen, Hidayat Ullah, Muhammad Mubarik, Waqar Azeem Jadoon, Shehzad Ghayyur, Muhammad Iftikhar, Shahryar Ghayyur","doi":"10.1007/s10646-025-02929-1","DOIUrl":"10.1007/s10646-025-02929-1","url":null,"abstract":"<p><p>The increasing use of pesticides threatens aquatic ecosystems. This study evaluated the toxic effects of carbosulfan, pyriproxyfen, thiamethoxam, and their mixture on the hemato-biochemical profile of Cyprinus carpio over a 30-day exposure period. The 96 h LC₅₀ values, determined via probit analysis, were 5.49 µg/L for carbosulfan, 8.91 µg/L for pyriproxyfen, and 11.48 µg/L for thiamethoxam. A total of 150 fish were divided into five groups (G1, G2, G3, G4, and G5), with 50 specimens in each group, and each treatment was replicated three times. Group G1 served as the control, while groups G2-G5 were exposed to 2.74 µg/L carbosulfan, 4.45 µg/L pyriproxyfen, 5.74 µg/L thiamethoxam, and a mixture of all three pesticides, respectively. The concentrations used correspond to 50% of each pesticide's 96 h LC₅₀ value. Blood samples were collected on the 15^th and 30^th days from both control and exposed groups for hemato-biochemical assessment. Results showed a significant (p < 0.05) decline in red blood cells, hemoglobin, hematocrit, and platelets, along with increased white blood cells across all treated groups. Mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration in pyriproxyfen- and thiamethoxam-treated groups increased insignificantly on day 15, but significantly (p < 0.05) on day 30 compared with controls. Pesticide exposure also resulted in a significant (p < 0.05) reduction in serum total protein, triglycerides, sodium, potassium, calcium, chloride, and thyroid hormones (T₃ and T₄). Conversely, glucose, cholesterol, urea, creatinine, phosphorus, iron, thyroid-stimulating hormone, cortisol, and liver enzymes aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and lactate dehydrogenase showed significant (p < 0.05) increases. The toxicity ranking was carbosulfan > mixture > pyriproxyfen > thiamethoxam. Our findings highlight the adverse effects of the combined use of the selected pesticides and support the efficacy of the multi-biomarker approach in elucidating the toxicological mechanisms induced by pesticide exposure.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1489-1505"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144567315","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing histological and molecular responses in goldfish exposed to copper sulfate: insights for sustainable aquatic health management.","authors":"Walaa M Shaalan, Fatma Rehan, Nassr Allah Abdel-Hameid","doi":"10.1007/s10646-025-02919-3","DOIUrl":"10.1007/s10646-025-02919-3","url":null,"abstract":"<p><p>This study investigates the impact of copper sulfate (CuSO₄) on goldfish (Carassius auratus), focusing on histological changes in gills, liver, and muscle tissues, as well as the expression patterns of key genes involved in muscle. Goldfish were exposed to three concentrations of CuSO₄ (1.998 mg/L, 3.995 mg/L, and 5.993 mg/L) for 96 h. Histological examination revealed dose-dependent pathological changes, including gill epithelial proliferation, hepatocyte degeneration, and muscle necrosis. Gene expression analyses indicated significant upregulation of IGF-1 in the liver at high CuSO₄ concentrations, while IGF-1 in muscle was consistently downregulated across all concentrations. MyoD gene expression was upregulated at the three tested concentrations, but it was the lowest at the highest concentration, whereas MURF2 was significantly upregulated in all experimental groups. These findings suggest that CuSO₄ exposure disrupts normal histological structure in goldfish, highlighting the need for stringent environmental regulations to mitigate copper pollution in aquatic ecosystems. This study provides critical insights into the molecular and histopathological mechanisms underlying CuSO₄ toxicity in fish, contributing to the development of evidence-based management strategies for aquatic conservation and aquaculture.</p>","PeriodicalId":11497,"journal":{"name":"Ecotoxicology","volume":" ","pages":"1506-1515"},"PeriodicalIF":2.7,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144607844","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"环境科学与生态学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}