Current Topics in Nutraceutical Research最新文献_第6页

Association of Vitamin D and Calcium Levels with Thyroid Status in the Southern Region of Saudi Arabia 沙特阿拉伯南部地区维生素D和钙水平与甲状腺状况的关系

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:283-290

S. Alqahtani

{"title":"Association of Vitamin D and Calcium Levels with Thyroid Status in the Southern Region of Saudi Arabia","authors":"S. Alqahtani","doi":"10.37290/ctnr2641-452x.21:283-290","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:283-290","url":null,"abstract":"Thyroid dysfunction is the most prevalent endocrine disorder worldwide. Thyroid hormone has a crucial role in maintaining a wide array of metabolic homeostasis. In addition to calcium and bone metabolism, vitamin D influences nonskeletal activities, including the thyroid gland. Therefore, hypovitaminosis D is considered a risk factor for the emergence of many thyroid dysfunctions. In this investigation, we aimed to investigate the association of vitamin D and serum calcium levels with thyroid dysfunction. In this investigation, 2,735 (1,438 females and 1,297 males) laboratory findings from the public, government hospital laboratories, and medical clinics serving chronic patients in the south region (Asir region) of Saudi Arabia were screened over the course of one year. The vitamin D level was significantly lower in both female and male patients in the hypothyroidism category than in the hyperthyroidism and euthyroidism groups. The influence of total serum calcium level was not significant in any thyroid dysfunction category. A high prevalence of normal levels of total serum calcium was observed in all thyroid status groups. A partial correlation between total serum calcium and vitamin D and TSH among thyroid dysfunction patients demonstrated a significant negative correlation between vitamin D and TSH and a nonsignificant negative correlation between total serum calcium level and TSH among hypothyroidism categories. However, in the hypothyroidism group, total serum calcium demonstrated a negative correlation with TSH, while vitamin D showed a positive correlation with TSH.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44810357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Combination of Thunder-Fire Moxibustion and Shenghua Decoction Enhances Uterine Involution After Cesarean Section and Postpartum Lactation 雷火灸加生花汤对剖宫产术后子宫复旧及产后泌乳的促进作用

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:248-253

Yanchun Cao, Yunyun He

{"title":"A Combination of Thunder-Fire Moxibustion and Shenghua Decoction Enhances Uterine Involution After Cesarean Section and Postpartum Lactation","authors":"Yanchun Cao, Yunyun He","doi":"10.37290/ctnr2641-452x.21:248-253","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:248-253","url":null,"abstract":"This study aimed to analyze the therapeutic effect of thunder-fire moxibustion plus Shenghua Decoction on uterine involution after cesarean section and its influence on lactation. One hundred and twenty parturients with post-cesarean section uterine involution were recruited from our hospital between October 2021 to July 2022. Participants were grouped into A, B, C, and D groups and treated with conventional therapy, Shenghua Decoction, thunder-fire moxibustion, and Shenghua Decoction+thunder-fire moxibustion, respectively. Groups B, C and D, especially group D, had shorter duration of lochia and faster descending speed of uterine fundus height than group A. All the four groups showed decreased uterine cavity volume after treatment, with the lowest volume found in group D. In terms of clinical efficacy, group D also had better treatment outcomes than the other three groups. Furthermore, the breast fullness degree and lactation yield scores were higher in group D than other groups, whilst the four groups were not statistically different in the incidence of adverse reactions. Shorter length of maternal hospital stays, and uterus recovery time were found in group D. In summary, thunder-fire moxibustion plus Shenghua Decoction should be treatment of choice for post-cesarean section uterine involution that can promote maternal breast milk secretion.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46221157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anacardic Acid Alleviates Hypoxia/ReoxygenationInduced Injury in Cardiomyocytes via Suppressing Nuclear Factor-Kappa B Pathway Anacardic Acid通过抑制核因子Kappa B途径减轻心肌细胞缺氧/再充氧损伤

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:208-214

Yao Liu, Qi-De Song, Ye Tian

引用次数: 0

Protective Effect of Hispolon on Postoperative Cognitive Dysfunction in a Sevoflurane-Induced HT-22 Cell Model Hispolon对七氟醚诱导的HT-22细胞模型术后认知功能障碍的保护作用

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:260-265

Hua Wang, Yanan Ji, Chuanju Liu, Jie Gao, Junjiao Hu

引用次数: 0

Efficacy and Safety Evaluation of Different Maintenance Dose Regimens of Caffeine Citrate in the Treatment of Primary Apnea in Preterm Infants 枸橼酸咖啡因不同维持剂量方案治疗早产儿原发性呼吸暂停的疗效和安全性评价

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:266-271

Xiao Zhang, Y. Liu, Debo Xu, Lin Li, Zhenyu Liang, Q. Meng, Xihua Huang

{"title":"Efficacy and Safety Evaluation of Different Maintenance Dose Regimens of Caffeine Citrate in the Treatment of Primary Apnea in Preterm Infants","authors":"Xiao Zhang, Y. Liu, Debo Xu, Lin Li, Zhenyu Liang, Q. Meng, Xihua Huang","doi":"10.37290/ctnr2641-452x.21:266-271","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:266-271","url":null,"abstract":"We have investigated the efficacy and safety of different maintenance doses of caffeine citrate in the treatment of primary apnea in preterm infants. To this end, apneic premature infants were treated with 5 mg/kg (low dose) or 10 mg/kg (high dose) caffeine citrate, and the frequency of apnea at 48 h and 72 h, improvement of clinical symptoms, respiratory mechanics parameters related to lung function, and blood gas analysis indexes were compared between the two groups, and safety was evaluated. The frequency of apnea at 48 h and 72 h was significantly lower in the high-dose group than in the low-dose group, and the difference was statistically significant (P < 0.05). The time to resolution of apnea, the time to mechanical ventilation, and the time to citrate use were significantly shorter in the high-dose group than in the low-dose group (P < 0.05). The tidal volume and peak expiratory flow values were significantly higher in the high-dose group than in the low-dose group (P < 0.05). The oxygen partial pressure and pulse oximetry levels in the blood gas analysis indexes of the high-dose group were significantly higher than those of the low-dose group, and the partial pressure of carbon dioxide level was significantly lower than that of the low-dose group, with statistically significant differences (P < 0.05). The safety evaluation results showed no significant difference in the rate of adverse reactions and short-term complications between the high-dose group and the low-dose group (P > 0.05). Caffeine citrate at a maintenance dose of 10 mg/kg can effectively reduce the frequency of apnea, shorten the improvement time of clinical symptoms, and improve the lung function and blood gas analysis level of children with a high safety profile.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43241078","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Amarogentin Alleviates Osteoarthritis by Regulating Chondrocyte Proliferation and Autophagy Amarogentin通过调节软骨细胞增殖和自噬减轻骨关节炎

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:254-259

Weiwei Luo, Dongjie Zhu, Yang Yang, Hongxia Li, Jianfeng Jin, Juanjuan Cai

{"title":"Amarogentin Alleviates Osteoarthritis by Regulating Chondrocyte Proliferation and Autophagy","authors":"Weiwei Luo, Dongjie Zhu, Yang Yang, Hongxia Li, Jianfeng Jin, Juanjuan Cai","doi":"10.37290/ctnr2641-452x.21:254-259","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:254-259","url":null,"abstract":"Although amarogentin has been shown to play an amelioration role in several disease states, its role in osteoarthritis progression remains unexplored. To this end, we have examined the role of amarogentin in interleukin-1β-treated chondrocytes, a cell model of osteoarthritis. We observed that chondrocyte proliferation was attenuated after interleukin-1β treatment, which was reversed by amarogentin treatment. In addition, the protein expressions for matrix metalloproteinase-3 and matrix metalloproteinase-9 were enhanced, and collagen II was reduced after interleukin-1β treatment, but these changes were reversed by amarogentin treatment, indicating that amarogentin inhibited interleukin-1β-stimulated extracellular matrix degradation. Moreover, amarogentin strengthened interleukin-1β-triggered chondrocyte autophagy by enhancing LC3II/LC3I, Beclin1, and Atg7 levels and reducing the level of P62, a cargo adaptor protein that interacts with autophagic substrates and delivers them to autophagosomes for degradation. Besides, the expressions of p-AMPK/AMPK and SIRT1 proteins were diminished after interleukin-1β treatment, but these effects were restored by amarogentin treatment, illustrating that amarogentin activated the AMPK/SIRT1 pathway. In conclusion, amarogentin alleviates osteoarthritis by regulating chondrocyte proliferation and autophagy through the AMPK/SIRT1 pathway.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69758159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comprehensive Nutritional Nursing Intervention in Elderly Patients with Chronic Obstructive Pulmonary Disease 老年慢性阻塞性肺疾病患者的综合营养护理干预

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:277-282

Ju-fang Jiang, Xiaofen Shi, Yan Wu

{"title":"Comprehensive Nutritional Nursing Intervention in Elderly Patients with Chronic Obstructive Pulmonary Disease","authors":"Ju-fang Jiang, Xiaofen Shi, Yan Wu","doi":"10.37290/ctnr2641-452x.21:277-282","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:277-282","url":null,"abstract":"The objective of this study was to probe the effect of comprehensive nutritional nursing on elderly patients with chronic obstructive pulmonary disease. To this end, a total of 82 elderly patients with chronic obstructive pulmonary disease were randomly divided equally into control (receiving conventional treatment) and nursing intervention (receiving conventional treatment and dietary nursing intervention) groups. The body mass index, forced expiratory volume in one second/forced vital capacity, plasma albumin, prealbumin, and hemoglobin levels in the observation group were higher in comparison with the control group. However, the self-rating anxiety scale and self-rating depression scale scores in the observation group were diminished compared to the control group. The scores of psychological, physiological, environmental, and social relations in the observation group were higher relative to the control group. The nursing satisfaction in the observation group was elevated compared to the control group. In conclusion, comprehensive nutritional nursing interventions can improve nutritional status, lung function, and quality of life in elderly patients with chronic obstructive pulmonary disease.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45591690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ulinastatin, A Multivalent Serine Protease Inhibitor, Improves Recovery of Pancreatic Cancer Patients Undergoing Laparoscopic Surgery 乌司他丁，一种多价丝氨酸蛋白酶抑制剂，改善癌症腹腔镜手术患者的恢复

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI: 10.37290/ctnr2641-452x.21:228-234

Xingjie Guo, Zhen Zhang, Huairui Li, A. Ho

引用次数: 0

A Combination of Enteral and Parenteral Nutrition Better Supports Postoperative Prognosis of Patients with Malignant Obstructive Jaundice 肠内营养和肠外营养相结合更有利于恶性阻塞性黄疸患者的术后预后

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-07-06 DOI: 10.37290/ctnr2641-452x.21:400-404

Fang Liu, Chuang Yang, Caixia Hou, Yun Ai, Yuqin Chen

{"title":"A Combination of Enteral and Parenteral Nutrition Better Supports Postoperative Prognosis of Patients with Malignant Obstructive Jaundice","authors":"Fang Liu, Chuang Yang, Caixia Hou, Yun Ai, Yuqin Chen","doi":"10.37290/ctnr2641-452x.21:400-404","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:400-404","url":null,"abstract":"A total of 120 patients admitted to affiliated hospitals of the North Sichuan Medical College between September 2020 and June 2022 were recruited for this study and received percutaneous transhepatic cholangial drainage. Patients in the control group received parenteral nutrition support, whereas patients in the treatment group received parenteral and combined enteral nutrition support. Compared to the control group, the time of first exhaustion and defecation in the treatment group was faster, and the postoperative activity time and hospital stay were shorter. Serum albumin and prealbumin levels in both groups decreased on the 1st day after surgery and recovered on the 7th day, with the treatment group reaching higher levels. After surgery, the decline in alanine aminotransferase, aspartate aminotransferase, total bilirubin, and direct bilirubin levels was higher in the treatment group. CD4+, CD8+ levels, and CD4+/CD8+ ratios in both groups were elevated, with the treatment group showing higher levels. The occurrence of complications in the treatment group was lessened relative to the control group. In summary, enteral combined parenteral nutrition support for patients with malignant obstructive jaundice after surgery can promote faster recovery of gastrointestinal function, improve nutritional status, facilitate the recovery of liver function, and promote immune function.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139362378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evaluation of Clinical Management of COVID-19 Patients in China in the Year 2020 2020年中国新冠肺炎患者临床管理评估

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-06-12 DOI: 10.37290/ctnr2641-452x.21:440-447

Jie Lin, Ting Zheng, Jiahui Guan, Feiyan Wang

{"title":"Evaluation of Clinical Management of COVID-19 Patients in China in the Year 2020","authors":"Jie Lin, Ting Zheng, Jiahui Guan, Feiyan Wang","doi":"10.37290/ctnr2641-452x.21:440-447","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:440-447","url":null,"abstract":"Our research aimed to analyze the application and outcome of several common antiviral drugs and the traditional Chinese medicine formulations for COVID-19 during the early months (January 20, 2020 to December 30, 2020) of the epidemics in China. Patients were clinically classified into mild, common, severe, and critical types based on their clinical symptoms, pulmonary imaging findings, and complications. During the study period, antiviral treatment was administered to 482 patients, with 342 patients receiving a combination of traditional Chinese and Western medicine, accounting for 80.60% and 57.19% of the discharged COVID-19 patients (598 cases), respectively. The main treatment consisted of monotherapy with lopinavir/ ritonavir, arbidol, and chloroquine phosphate, with a need to change the treatment regimen in 29.88% of patients. Three traditional Chinese medicine formulations—Huoxiangzhengqi Liquid, Lianhuaqingwen Jiaonang, and Shufeng Jiedu Jiaonang—were used for COVID-19 treatment and showed good curing effects for patients with mild common clinical classification. Antiviral-related adverse effects were experienced by a total of 142 patients (29.46%). To sum up, antiviral and TCM treatments remain the mainstays of therapy for COVID-19 and show good effects.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136369741","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0