Current Topics in Nutraceutical Research最新文献_第7页

Detection of Carbamates and Nitrites with a Linear Transport Unit Connected to a Paper-Based Multiplexed Colorimetric Platform for Food Safety 与纸质多路比色平台连接的线性传输单元检测氨基甲酸盐和亚硝酸盐的食品安全

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-05-28 DOI: 10.37290/ctnr2641-452x.21:448-453

Sung-Yu Wu, Yu-Chien Hung, Kuan-Hung Chen, Connie Chen, Chao-Min Cheng, Min-Yen Hsu

{"title":"Detection of Carbamates and Nitrites with a Linear Transport Unit Connected to a Paper-Based Multiplexed Colorimetric Platform for Food Safety","authors":"Sung-Yu Wu, Yu-Chien Hung, Kuan-Hung Chen, Connie Chen, Chao-Min Cheng, Min-Yen Hsu","doi":"10.37290/ctnr2641-452x.21:448-453","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:448-453","url":null,"abstract":"The COVID-19 pandemic and its associated restrictions made the concept of home testing increasingly popular. Here, we designed a linear transport unit connected to a paper-based multiplexed colorimetric platform, which can be used to test for food safety and physiological status. The device is composed of a linear transport unit and a paper-based multiplexed colorimetric reaction unit. The linear transporting unit uses the capillary phenomenon to collect samples, and the multiplexed colorimetric reaction unit can be used to detect different targets using a hydrophilic area and wax as the hydrophobic barrier. A rapid and multiplexed naked-eye readout of the colorimetric response is achieved in a few minutes. In this study, we demonstrate that the device can be used to detect nitrite, pesticides, lactate, and glycogen. It is a convenient and cheap home self-testing device that can be applied to different situations. This device could lead to earlier screening and, consequently, earlier referrals for further confirmation and treatment.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135897627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Optimizing Biosynthesis of Nicotinamide Mononucleotide, a Potential Nutritional Supplement, by E. coli 大肠杆菌优化潜在营养补充剂烟酰胺单核苷酸的生物合成

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-05-05 DOI: 10.37290/ctnr2641-452x.21:198-207

Yujuan Cao, Lun Cui

引用次数: 0

Role of Garlic (Allium Sativum L.) in Chronic Kidney Diseases: A Short Review 大蒜在慢性肾脏疾病中的作用

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-05-02 DOI: 10.37290/ctnr2641-452x.21:1-4

Chien-Ming Lin, Huangfu Chao, Han-Fang Tseng, Chih-Hung Lin, C. Kuo

引用次数: 0

Role of Garlic (Allium Sativum L.) in Chronic Kidney Diseases: A Short Review 大蒜在慢性肾脏疾病中的作用综述

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-05-02 DOI: 10.37290/ctnr2641-452x.21:194-197

Chien-Ming Lin, Huan-Nung Chao, Han-Fang Tseng, Chih-Hung Lin, Chan-Yen Kuo

引用次数: 0

Functional Assessment of Therapy Tools for Cancer Cachexia: A Review 癌症恶病质治疗工具的功能评价综述

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-04-18 DOI: 10.37290/ctnr2641-452x.21:187-193

Lee Tang, John Jenn Yenn Lu, Sheau-Chung Tang

引用次数: 0

The Effects of Medium-Term Intake of Hydrogen-Rich Water on Sperm Quality Biomarkers in Normospermic and Oligospermic Men: A Randomized Controlled Pilot Trial 中期摄入富氢水对正常精子和少精子男性精子质量生物标志物的影响:一项随机对照试验

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-04-11 DOI: 10.37290/ctnr2641-452x.21:182-186

V. Štajer, N. Todorovic, Branislava Drdjenovic Conic, N. Kladar, D. Engeset, T. H. Stea, L. Rátgéber, S. Forbes, D. Candow, S. Ostojić

{"title":"The Effects of Medium-Term Intake of Hydrogen-Rich Water on Sperm Quality Biomarkers in Normospermic and Oligospermic Men: A Randomized Controlled Pilot Trial","authors":"V. Štajer, N. Todorovic, Branislava Drdjenovic Conic, N. Kladar, D. Engeset, T. H. Stea, L. Rátgéber, S. Forbes, D. Candow, S. Ostojić","doi":"10.37290/ctnr2641-452x.21:182-186","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:182-186","url":null,"abstract":"The main aim of this randomized controlled pilot trial was to evaluate the effects of hydrogen-rich water on spermiogram parameters in normospermic and oligospermic men. As many as 12 healthy young men (age 29.1 ± 5.9 years; n = 6 normospermic; n = 6 oligospermic) volunteered. Participants were allocated in a double-blind manner to receive 1 L of hydrogen-rich water per day or 1 L of tap water fortified with magnesium for 8 weeks. Following hydrogen-rich water supplementation, sperm concentration and morphology tended to increase by 12.4 million per milliliter (95% CI; –31.8 to 56.6), and live cells increased by 3.8% (95% CI; –12.5 to 20.1), respectively (P ≤ 0.30). A significant difference between the two interventions was found in sperm vitality (P = 0.03), with hydrogen-rich water being superior to the placebo in terms of an increase in the number of live sperm cells. Subgroup analyses revealed no significant differences between interventions in sperm viability outcomes in oligospermic men (P > 0.05). However, sperm count increased by over 20 million in two of the three oligospermic men (66.7%) receiving hydrogen-rich water, while no oligospermic men in the placebo group increased sperm concentration to euspermic levels (P < 0.01). These preliminary findings suggest hydrogen-rich water is an effective intervention for improving some aspects of male subfertility; further large-sample trials are warranted to corroborate our results.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42593532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Plantamajoside Reduces Gastric Cancer Cell Migration and Invasion by Inhibiting PI3K/AKT and ERK Pathways 车前草皂苷通过抑制PI3K/AKT和ERK通路减少胃癌细胞的迁移和侵袭

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-04-11 DOI: 10.37290/ctnr2641-452x.21:175-181

Cheng-fang Tang, Yuanyuan Wang, Jing Huang, Xiaohong Lv

{"title":"Plantamajoside Reduces Gastric Cancer Cell Migration and Invasion by Inhibiting PI3K/AKT and ERK Pathways","authors":"Cheng-fang Tang, Yuanyuan Wang, Jing Huang, Xiaohong Lv","doi":"10.37290/ctnr2641-452x.21:175-181","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:175-181","url":null,"abstract":"Gastric cancer is a common malignancy with a poor survival rate. Plantamajoside, a phenylethanoid glycoside from Plantago asiatica, has been shown to inhibit the progression of many different types of cancer; however, its effect on gastric cancer remains to be explored. To this end, the effect of plantamajoside on the proliferation, apoptosis, stemness, mobility, and invasion of gastric cancer was evaluated by cell survival assay, flow cytometry, colony formation, sphere formation, transwell, and Western blot assays. Also, the potential molecular mechanism was addressed by Western blot assays for the expression of various signal proteins. Plantamajoside reduced cell viability, enhanced apoptosis, reduced cell mobility, and increased invasion of both AGS and HS746T cells in a dose-dependent manner. Plantamajoside also decreased the diameter of the spheroid and the relative expression of octamer-binding transcription factor-4 and the cluster of differentiation 44 proteins in both AGS and HS746T cells. Furthermore, plantamajoside downregulated the relative protein levels of p-PI3K/ PI3K, p-AKT/AKT, and p-ERK/ERK in both AGS and HS746T cells.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-04-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42551756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protection of Neuronal Cells from Lipopolysaccharide-Induced Systemic Inflammation by Gossypetin 棉酚素对神经元细胞的保护作用

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-04-07 DOI: 10.37290/ctnr2641-452x.21:138-143

Soyoung Jang, Soyeon Jang, Jiwon Ko, Eungyung Kim, Hyejin Hyung, Ji Yeong Park, Su-Geun Lim, S. Park, M. Kim, Z. Ryoo

{"title":"Protection of Neuronal Cells from Lipopolysaccharide-Induced Systemic Inflammation by Gossypetin","authors":"Soyoung Jang, Soyeon Jang, Jiwon Ko, Eungyung Kim, Hyejin Hyung, Ji Yeong Park, Su-Geun Lim, S. Park, M. Kim, Z. Ryoo","doi":"10.37290/ctnr2641-452x.21:138-143","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:138-143","url":null,"abstract":"Systemic inflammation caused by infection, surgery, or injury can lead to cognitive decline. Lipopolysaccharides are known as toll-like receptor 4 ligands, which are common to the cell walls of gram-negative bacteria. Activation of toll-like receptor 4 leads to the production of proinflammatory cytokines that subsequently mediate systemic inflammation. Furthermore, induc¬tion of systemic inflammation by lipopolysaccharide injection in mice can affect the brain, including cognitive functions. To investigate the neuroprotective role of gossypetin in systemic inflammation, a mouse hippocampal cell line (HT22) and mice were challenged with lipopolysaccharide. The increase in proinflammatory cytokines and reactive oxygen species caused by lipopolysaccharide treatment in HT22 cells was decreased by gossypetin treatment. To evaluate the protective function against memory impairment, gossypetin was orally administered to C57BL/6J mice receiving lipopolysaccharide injec¬tion. Lipopolysaccharide-induced memory deficit was observed in lipopolysaccharide-only treated group in Y-maze test. However, the group treated with gossypetin and lipopolysaccharide had a diminution in cognitive impairment. Consistent with the behavioral test results, the proinflammatory cytokines were also relatively downregulated in the gossypetin-treated mouse group. To sum up, gossypetin can be protect the neuron cells from inflammation in vitro and prevent the cognitive impairment in mice in vivo.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47818170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Physalin A Enhances Autophagy and Suppresses Oxidative Stress Injury and Extracellular Matrix Deposition in Diabetic Nephropathy Physalin A促进糖尿病肾病的自噬，抑制氧化应激损伤和细胞外基质沉积

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-04-07 DOI: 10.37290/ctnr2641-452x.21:131-137

Miao Zhang, Dan-dan Huang, Dan Chen, Taotao Hu

引用次数: 0

Effect of Huangqi Granules Combined with Budesonide on Clinical Indexes, Clinical Efficacy, and Safety in Children with Bronchial Asthma 黄芪颗粒联合布地奈德对儿童支气管哮喘临床指标、疗效及安全性的影响

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-04-07 DOI: 10.37290/ctnr2641-452x.21:169-174

Fuzhe Chen, Lei Liang, Changlong Lu, Chongyu Xu

引用次数: 0