Current Topics in Nutraceutical Research最新文献_第2页

Improvement of Nutritional Status of Patients with Adenomyosis Combined with Lower Extremity Deep Venous Thrombosis by Combination Therapy 通过联合疗法改善子宫腺肌症合并下肢深静脉血栓患者的营养状况

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2024-01-06 DOI: 10.37290/ctnr2641-452x.22:485-491

Shouguang Sui, Chang Li, Ganchun Wu, Ping Sui, Cong Li, Mingxin Wang

{"title":"Improvement of Nutritional Status of Patients with Adenomyosis Combined with Lower Extremity Deep Venous Thrombosis by Combination Therapy","authors":"Shouguang Sui, Chang Li, Ganchun Wu, Ping Sui, Cong Li, Mingxin Wang","doi":"10.37290/ctnr2641-452x.22:485-491","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.22:485-491","url":null,"abstract":"This study aims to explore the effect of a comprehensive treatment scheme comprising conservative surgery, postoperative continuous subcutaneous infusion of gonadotrophin-releasing hormone agonist, rehabilitation training, and rivaroxaban on patients with adenomyosis complicated with lower extremity deep venous thrombosis and to provide a clinical reference. The study results showed that compared to the conventional treatment regimen, patients with adenomyosis combined with lower extremity deep venous thrombosis exhibited significant improvements in uterine function, thrombotic status, and coagulation after the combination therapy. In addition, they demonstrated superior nutritional status and a reduced risk grade for malnutrition. Based on these results, we believe that the combination of conservative surgery, postoperative continuation of gonadotrophin-releasing hormone agonist, rehabilitation, and rivaroxaban has higher clinical value in the treatment of adenomyosis combined with lower extremity deep venous thrombosis than the conventional treatment regimen.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140513217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Resveratrol in Periodontitis Treatment: Efficacy and Mechanism of Action in Rat Models and its Clinical Implications 白藜芦醇治疗牙周炎：白藜芦醇在大鼠模型中的疗效和作用机制及其临床意义

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2024-01-06 DOI: 10.37290/ctnr2641-452x.22:452-458

Mei Chai, Xuyan Tang, Jinzhong Zhang, Chenchen Huang

{"title":"Resveratrol in Periodontitis Treatment: Efficacy and Mechanism of Action in Rat Models and its Clinical Implications","authors":"Mei Chai, Xuyan Tang, Jinzhong Zhang, Chenchen Huang","doi":"10.37290/ctnr2641-452x.22:452-458","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.22:452-458","url":null,"abstract":"Periodontitis, a prevalent periodontal disease, serves as the foundation for numerous periodontal pathologies. The current study aimed to examine the adjunctive role of resveratrol in treating periodontitis. Our findings reveal that resveratrol significantly augments periodontal health of patients, indicating its substantial efficacy. Further experimentation involving the construction of a rat model of periodontitis demonstrated that resveratrol effectively mitigates periodontal tissue damage and inhibits apoptosis in periodontal cells. This confirms resveratrol's promising clinical applicability. Moreover, the Osteoclastogenesis inhibitory factor/Recombinant receptor activator of nuclear factor kappa B/Recombinant receptor activator of nuclear factor kappa B-Ligand pathway is pivotal in modulating the pathological progression of periodontitis. This pathway exhibited significant activation in rats afflicted with periodontitis, and resveratrol intervention effectively regulated its expression. These findings suggest that the therapeutic impact of resveratrol on periodontitis could be attributed to the inhibition of the Osteoclastogenesis inhibitory factor/Recombinant receptor activator of nuclear factor kappa B/Recombinant receptor activator of nuclear factor kappa B-Ligand pathway.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-01-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140513303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sargent Gloryvine Extract Modulates Nuclear Factor κκB Signaling Pathway to Improve Severe Pancreatitis 沙金藤提取物可调节核因子κκB 信号通路，改善重症胰腺炎症状

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2024-01-04 DOI: 10.37290/ctnr2641-452x.22:405-411

Handong Mei, Xu Xiao, Xu Sinan

{"title":"Sargent Gloryvine Extract Modulates Nuclear Factor κκB Signaling Pathway to Improve Severe Pancreatitis","authors":"Handong Mei, Xu Xiao, Xu Sinan","doi":"10.37290/ctnr2641-452x.22:405-411","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.22:405-411","url":null,"abstract":"This study explored the mechanism of action of Sargent gloryvine extract in treating severe pancreatitis. We used the PubChem and SwissTargetPredicton databases to predict the potential targets. The database for Annotation, Visualization, and Integrated Discovery was used to perform Gene Ontology. The Kyoto Encyclopedia of Genes was used to perform Genomes enrichment analyses. These analyses, visualized via Cytoscape software followed by molecular docking validation, identified Salidroside, Lignans, Emodin, and Physcion as key active compounds in the extract. The protein-protein interaction network analysis highlighted tumor necrosis factor, interleukin-6, and nuclear factor κB as critical targets with 42 signaling pathways identified as relevant. The nuclear factor κB pathway emerged as especially significant in the extract's effect on severe pancreatitis. Enrichment analysis screened 42 related signaling pathways, among which the nuclear factor κB pathway may play a vital role in treating severe pancreatitis with Sargent gloryvine extract. The molecular docking results indicated an excellent binding activity between Sargent gloryvine extract and nuclear factor κB. In conclusion, the therapeutic approach of Sargent gloryvine extract in severe pancreatitis involves a complex interaction of multiple components, targets, and pathways, with a potential mechanism linked to the downregulation of the nuclear factor κB signaling pathway.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140513908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Individualized Nursing Based on Stress Adaptation Theory on Nutritional Status and Gastrointestinal Motility of Preterm Infants 基于压力适应理论的个性化护理对早产儿营养状况和胃肠道蠕动的影响

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-10-19 DOI: 10.37290/ctnr2641-452x.21:502-508

Huimin Li

引用次数: 0

Comparing Efficacy of Rhodiola Rosea, Red Goji Berry, and Siraitia Grosvenorii in Physical Recovery After Aerobic Exercise 红景天、枸杞子和罗汉果有氧运动后身体恢复效果的比较

IF 0.5 4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-10-09 DOI: 10.37290/ctnr2641-452x.21:326-331

S. Zheng, D.W. Liu

{"title":"Comparing Efficacy of Rhodiola Rosea, Red Goji Berry, and Siraitia Grosvenorii in Physical Recovery After Aerobic Exercise","authors":"S. Zheng, D.W. Liu","doi":"10.37290/ctnr2641-452x.21:326-331","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:326-331","url":null,"abstract":"This manuscript compares the effects of Rhodiola rosea, red goji berry, and Siraitia grosvenorii on the recovery of physical strength in athletes after aerobic exercise. Subjects were compared for the effects of different treatments on changes in physiological (heart rate, rating of perceived exertion, and vertical jump-and-reach performance) and biochemical (blood lactic acid, creatine kinase, and blood urea nitrogen) markers after four weeks of aerobic exercise. After four weeks of aerobic exercise, the heart rate of all groups of athletes increased rapidly, the level of fatigue deepened, the vertical jump-andreach performance decreased, and the levels of blood lactic acid, creatine kinase, and blood urea nitrogen all increased to varying degrees. At the 12th minute after exercise, the heart rate of the Rhodiola rosea group, the red goji berry group, and the Siraitia grosvenorii group recovered faster, the RPE value was lower, and the vertical jump-and-reach performance was better compared with the control, P < 0.05; moreover, the levels of all three biochemical markers were all significantly lower than those of the control group. In conclusion, the intake of these nutrients can promote the recovery of physical strength in athletes, accelerate the clearance of blood lactate, and inhibit the generation of creatine kinase and blood urea nitrogen. Therefore, they can be used as nutritional support for athletes during aerobic exercise.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.5,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47475573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Elemene Promotes Clinical Efficacy of Multiple Kinase Inhibitor Lenvatinib and Programmed Death-1 Inhibitor Tislelizumab Combination in Advanced Hepatocellular Carcinoma 榄香烯促进多激酶抑制剂Lenvatinib和程序性死亡-1抑制剂Tislelizumab联合治疗晚期肝细胞癌的临床疗效

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-10-09 DOI: 10.37290/ctnr2641-452x.21:386-394

Jie Duan, Wei Chen, Changhao Chen, Fangnan Song, Faxi Chen, Fangfang Jiang, Huiwen Xing, Aidong Gu

{"title":"Elemene Promotes Clinical Efficacy of Multiple Kinase Inhibitor Lenvatinib and Programmed Death-1 Inhibitor Tislelizumab Combination in Advanced Hepatocellular Carcinoma","authors":"Jie Duan, Wei Chen, Changhao Chen, Fangnan Song, Faxi Chen, Fangfang Jiang, Huiwen Xing, Aidong Gu","doi":"10.37290/ctnr2641-452x.21:386-394","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:386-394","url":null,"abstract":"We have examined the effect of added elemene on the clinical efficacy of combined treatment of advanced hepatocellular carcinoma with lenvatinib and tislelizumab chemotherapy. Patients with advanced hepatocellular carcinoma (n = 150) were divided into groups of equal size and treated with the multi-kinase inhibitor lenvatinib plus the PD-1 inhibitor tislelizumab alone (control) or along with elemene (treatment), a plant sesquiterpene with antiproliferative effects. The results of the study show a higher objective response rate and local control rate, superior post-treatment liver function, immune function, anti-angiogenesis capacity, and better quality of life, as reflected by higher functional assessment of cancer therapy scores (P < 0.05). Additionally, after treatment, albumin and prealbumin were elevated, and patient-generated subjective global assessment scores declined in both groups after treatment, but no difference was found between the two groups (P > 0.05). To sum up, elemene added to lenvatinib and tislelizumab chemotherapy is effective in treating advanced hepatocellular carcinoma patients and is recommended for clinical use.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135043478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Skin Carotenoid Score as an Important Prognostic Factor for Predicting Type 2 Diabetes Mellitus in Middle-Aged Subjects 皮肤类胡萝卜素评分作为预测中年人2型糖尿病的重要预后因素

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-10-09 DOI: 10.37290/ctnr2641-452x.21:373-379

Hans Hsientsai Wu, Jian-Jung Chen, Yi-Chuan Chen, Bagus Haryadi

{"title":"Skin Carotenoid Score as an Important Prognostic Factor for Predicting Type 2 Diabetes Mellitus in Middle-Aged Subjects","authors":"Hans Hsientsai Wu, Jian-Jung Chen, Yi-Chuan Chen, Bagus Haryadi","doi":"10.37290/ctnr2641-452x.21:373-379","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:373-379","url":null,"abstract":"This study aimed at identifying middle-aged subjects at risk for developing type 2 diabetes mellitus using noninvasive skin carotenoid and vascular function measurements. To this end, 61 subjects (40–65 years of age) without type 2 diabetes mellitus (Group A, Hemoglobin A1c < 6.5%) and 69 subjects (40–65 years of age) with type 2 diabetes mellitus (Group B, Hemoglobin A1c ≥ 6.5%) were recruited (Table 1). The skin carotenoid score was recorded using spectroscopy-based skin carotenoid measurements that approximate dietary fruit and vegetable intake. Endothelial function and heart rate variability were measured for the two groups and correlated with skin carotenoids scores. The daily vegetable and fruit intake was positively correlated with the skin carotenoids score in both groups (Group A, r = 0.598, p < 0.001; Group B, r = 0.449, p < 0.001). There were also significant differences in skin carotenoids score, indices of endothelial function, and heart rate variability between the subjects in group A and group B. There was a negative correlation between skin carotenoids score and individual determinants of metabolic syndrome, including high-density lipoprotein (r = −0.361, p = 0.009), waist circumference (r = −0.450, p < 0.001), fasting blood sugar (r = −0.713, p < 0.001), and Hemoglobin A1c (r = −0.808, p < 0.001); however, systolic blood pressure showed no significant correlation (p = 0.06). In conclusion, carotenoids and cardiovascular parameters are reliable predictive factors of type 2 diabetes mellitus in middle-aged subjects.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135043468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dietary Fiber Enteral Nutrition Accelerates Recovery Patients Undergoing Gynecological Laparoscopic Surgery 膳食纤维肠内营养加速妇科腹腔镜手术患者的恢复

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-10-09 DOI: 10.37290/ctnr2641-452x.21:368-372

Miao Li, Pengchong Di, Kun Liu, Ting Gao, Mingkun Wu, Kejuan Sun

{"title":"Dietary Fiber Enteral Nutrition Accelerates Recovery Patients Undergoing Gynecological Laparoscopic Surgery","authors":"Miao Li, Pengchong Di, Kun Liu, Ting Gao, Mingkun Wu, Kejuan Sun","doi":"10.37290/ctnr2641-452x.21:368-372","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:368-372","url":null,"abstract":"The influence of dietary fiber enteral nutrition support on promoting the recovery of intestinal function in patients who underwent gynecological laparoscopic surgery was investigated. To this end, patients were given dietary fiber (treatment group) or nondietary (control group) fiber enteral nutrition support after surgery, and the recovery time of bowel sounds, the time of first anal exhaustion, and defecation between the two groups were compared. After surgery, the recovery time of bowel sounds, the time of first anal exhaust and defecation in the treatment group were shorter than the control group (P < 0.05). Serum D-lactic acid, diamine oxidase, c-reactive protein, interleukin-6, tumor necrosis factor-α, and procalcitonin levels in the treatment group were lower than those in the control group (P < 0.05). However, albumin, pre-albumin, and transferrin levels in the treatment group were higher than those in the control group (P < 0.05). The occurrence of postoperative intestinal complications in the treatment group was lower relative to the control group (P < 0.05). To sum up, enteral nutrition containing dietary fiber can improve the intestinal barrier function and nutritional status of patients undergoing gynecological laparoscopic surgery, reduce the inflammatory response, and accelerate the recovery of gastrointestinal function.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135043470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Nutritional Management of Infertility in Patients with Polycystic Ovary Syndrome 多囊卵巢综合征患者不孕的营养管理

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-10-09 DOI: 10.37290/ctnr2641-452x.21:361-367

Ya Zhang, Jinglin Wu, Yanan Gao, Fang Ge

{"title":"Nutritional Management of Infertility in Patients with Polycystic Ovary Syndrome","authors":"Ya Zhang, Jinglin Wu, Yanan Gao, Fang Ge","doi":"10.37290/ctnr2641-452x.21:361-367","DOIUrl":"https://doi.org/10.37290/ctnr2641-452x.21:361-367","url":null,"abstract":"To investigate the role of the Internet-based and health care cluster model in the nutritional management of infertile patients with polycystic ovary syndrome, we compared the body mass index, insulin resistance index, serum testosterone level, anxiety level, depression level, and disease-related quality of life status of the control group with those receiving regular healthy lifestyle guidance and management. Lifestyle management was carried out through assessment, screening, status analysis, setting body mass management goals, diet management, exercise management, behavior management, and health guidance. After the intervention, the body mass index, insulin resistance index, and serum testosterone levels of the intervention group were lower (P < 0.05) than those of the control group. The scores of the generalized anxiety scale and patient health questionnaire were lower than those of the control group; the scores of the revised patient survival quality scale were higher than those of the control group, and the differences were statistically significant (P < 0.05). The life nutrition management program based on the Internet and healthcare group model is beneficial in modifying the patients’ endocrine metabolic status, relieving anxiety and depression, and improving their quality of life.","PeriodicalId":10976,"journal":{"name":"Current Topics in Nutraceutical Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-10-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135043611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antioxidant Activity of Acid Pretreated Gelatin Extracted from Duck Skin By-Products 酸预处理鸭皮副产品明胶的抗氧化活性研究

4区医学

Current Topics in Nutraceutical Research Pub Date : 2023-10-09 DOI: 10.37290/ctnr2641-452x.21:346-349

Nisansala Chandimali, Mirae Oh, Hyung-Jin Lim, Yeong-Seon Won, Seon-Gyeong Bak, Eun Hyun Park, Seung-Jae Lee

引用次数: 0