通脉糖炎明胶囊对斑马鱼糖尿病视网膜病变的影响

IF 0.4 4区医学 Q4 NUTRITION & DIETETICS

Current Topics in Nutraceutical Research Pub Date : 2023-09-10 DOI:10.37290/ctnr2641-452x.21:321-325

Qian Guo, Honggang Ni, Xinjie Wang, Long Ling

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引用次数: 0

摘要

研究通脉糖炎明胶囊对斑马鱼糖尿病视网膜病变的影响。对斑马鱼腹腔注射链脲佐菌素刺激糖尿病视网膜病变。通脉糖炎明胶囊通过调节促炎生物标志物和一氧化氮的表达，减缓糖尿病斑马鱼视网膜病变的进展。本研究结果为该药在糖尿病视网膜病变治疗中的应用提供了实验依据，增加了糖尿病视网膜病变发展预防药物的选择。

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Effect of Tongmai Tangyanming Capsules on Diabetic Retinopathy in Zebrafish

The effect of Tongmai Tangyanming Capsules on diabetic retinopathy in zebrafish was investigated. Zebrafish were intraperitoneally injected with streptozotocin to stimulate diabetic retinopathy. Treatment of diabetic zebrafish with Tongmai Tangyanming Capsules diminished the progression of diabetic retinopathy by regulating the expression of pro-inflammatory biomarkers and nitric oxide. The results of this study offer an experimental basis for the use of this drug in diabetic retinopathy treatment and increase the selection of preventive drugs for diabetic retinopathy development.

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来源期刊

Current Topics in Nutraceutical Research 医学-药学

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Current Topics in Nutraceutical Research is an international, interdisciplinary broad-based peer reviewed scientific journal for critical evaluation of research on chemistry, biology and therapeutic applications of nutraceuticals and functional foods. The major goal of this journal is to provide peer reviewed unbiased scientific data to the decision makers in the nutraceutical and food industry to help make informed choices about development of new products. To this end, the journal will publish two types of review articles. First, a review of preclinical research data coming largely from animal, cell culture and other experimental models. Such data will provide basis for future product development and/or human research initiatives. Second, a critical evaluation of current human experimental data to help market and deliver the product for medically proven use. This journal will also serve as a forum for nutritionists, internists, neurologists, psychiatrists, and all those interested in preventive medicine. The common denominator of all of the topic to be covered by the journal must include nutraceuticals and/functional food. The following is an example of some specific areas that may be of interest to the journal. i) Role of vitamins, minerals, antioxidants and phytonutrients on cardiovascular health, cancer, diabetes, ocular health, mental health, men’s health, women’s health, infant nutrition, ii) Role of herbals on human health, iii) Dietary supplements and sleep, iv) Components of diet that may have beneficial effect on human health, v) regulation of apoptosis and cell viability, vi) Isolation and characterization of bioactive components from functional foods, vii) Nutritional genomics, and viii) Nutritional proteomics.