Critical Reviews in Biotechnology最新文献_第7页

Bioactive compounds from Cordyceps and their therapeutic potential. 冬虫夏草中的生物活性化合物及其治疗潜力。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-08-01 Epub Date: 2023-07-30 DOI: 10.1080/07388551.2023.2231139

Kondapalli Vamsi Krishna, Rutwick Surya Ulhas, Alok Malaviya

{"title":"Bioactive compounds from Cordyceps and their therapeutic potential.","authors":"Kondapalli Vamsi Krishna, Rutwick Surya Ulhas, Alok Malaviya","doi":"10.1080/07388551.2023.2231139","DOIUrl":"10.1080/07388551.2023.2231139","url":null,"abstract":"The Clavicipitaceae family's largest and most diverse genus is Cordyceps. They are most abundant and diverse in humid temperate and tropical forests and have a wide distribution in: Europe, North America, and East and Southeast Asian countries, particularly: Bhutan, China, Japan, Nepal, Korea, Thailand, Vietnam, Tibet, and the Himalayan region of India, and Sikkim. It is a well-known parasitic fungus that feeds on insects and other arthropods belonging to 10 different orders. Over 200 bioactive metabolites, that include: nucleotides and nucleosides, polysaccharides, proteins, polypeptides, amino acids, sterols, and fatty acids, among others have been extracted from Cordyceps spp. demonstrating the phytochemical richness of this genus. These components have been associated with a variety of pharmacological effects, including: anti-microbial, anti-apoptotic, anti-cancer, anti-inflammatory, antioxidant, and immunomodulatory activities. In this paper, the bioactivity of various classes of metabolites produced by Cordyceps spp., and their therapeutic properties have been reviewed in an attempt to update the existing literature. Furthermore, one of its nucleoside and a key bioactive compound, cordycepin has been critically elaborated with regard to its biosynthesis pathway and the recently proposed protector-protégé mechanism as well as various biological and pharmacological effects, such as: suppression of purine and nucleic acid biosynthesis, induction of apoptosis, and cell cycle regulation with their mechanism of action. This review provides current knowledge on the bioactive potential of Cordyceps spp.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"753-773"},"PeriodicalIF":8.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9897057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites. 不定根培养的生物反应器配置：专门代谢物商业化生产的最新进展。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-08-01 Epub Date: 2023-07-27 DOI: 10.1080/07388551.2023.2233690

Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Kee Yoeup Paek, So Young Park

{"title":"Bioreactor configurations for adventitious root culture: recent advances toward the commercial production of specialized metabolites.","authors":"Hosakatte Niranjana Murthy, Kadanthottu Sebastian Joseph, Kee Yoeup Paek, So Young Park","doi":"10.1080/07388551.2023.2233690","DOIUrl":"10.1080/07388551.2023.2233690","url":null,"abstract":"In vitro plant cell and organ cultures are appealing alternatives to traditional methods of producing valuable specialized metabolites for use as: pharmaceuticals, food additives, cosmetics, perfumes, and agricultural chemicals. Cell cultures have been adopted for the production of specialized metabolites in certain plants. However, in certain other systems, adventitious roots are superior to cell suspension cultures as they are organized structures that accumulate high levels of specialized metabolites. The cultivation of adventitious roots has been investigated in various bioreactor systems, including: mechanically agitated, pneumatically agitated, and modified bioreactors. The main relevance and importance of this work are to develop a long-lasting industrial biotechnological technology as well as to improve the synthesis of these metabolites from the plant in vitro systems. These challenges are exacerbated by: the peculiarities of plant cell metabolism, the complexity of specialized metabolite pathways, the proper selection of bioreactor systems, and bioprocess optimization. This review's major objective is to analyze several bioreactor types for the development of adventitious roots, as well as the advantages and disadvantages of each type of bioreactor, and to describe the strategies used to increase the synthesis of specialized metabolites. This review also emphasizes current advancements in the field, and successful instances of scaled-up cultures and the generation of specialized metabolites for commercial purposes are also covered.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"837-859"},"PeriodicalIF":8.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9937648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Strategies to improve the efficiency and quality of mutant breeding using heavy-ion beam irradiation. 利用重离子束辐照提高突变体培育效率和质量的策略。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-08-01 Epub Date: 2023-07-16 DOI: 10.1080/07388551.2023.2226339

Xiaopeng Guo, Junle Ren, Xiang Zhou, Miaomiao Zhang, Cairong Lei, Ran Chai, Lingxi Zhang, Dong Lu

{"title":"Strategies to improve the efficiency and quality of mutant breeding using heavy-ion beam irradiation.","authors":"Xiaopeng Guo, Junle Ren, Xiang Zhou, Miaomiao Zhang, Cairong Lei, Ran Chai, Lingxi Zhang, Dong Lu","doi":"10.1080/07388551.2023.2226339","DOIUrl":"10.1080/07388551.2023.2226339","url":null,"abstract":"Heavy-ion beam irradiation (HIBI) is useful for generating new germplasm in plants and microorganisms due to its ability to induce high mutagenesis rate, broad mutagenesis spectrum, and excellent stability of mutants. However, due to the random mutagenesis and associated mutant breeding modalities, it is imperative to improve HIBI-based mutant breeding efficiency and quality. This review discusses and summarizes the findings of existing theoretical and technical studies and presents a set of tandem strategies to enable efficient and high-quality HIBI-based mutant breeding practices. These strategies: adjust the mutation-inducing techniques, regulate cellular response states, formulate high-throughput screening schemes, and apply the generated superior genetic elements to genetic engineering approaches, thereby, improving the implications and expanding the scope of HIBI-based mutant breeding. These strategies aim to improve the mutagenesis rate, screening efficiency, and utilization of positive mutations. Here, we propose a model based on the integration of these strategies that would leverage the advantages of HIBI while compensating for its present shortcomings. Owing to the unique advantages of HIBI in creating high-quality genetic resources, we believe this review will contribute toward improving HIBI-based breeding.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"735-752"},"PeriodicalIF":8.1,"publicationDate":"2024-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9783888","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The bioactivities and biotechnological production approaches of carotenoids derived from microalgae and cyanobacteria. 从微藻和蓝藻中提取的类胡萝卜素的生物活性和生物技术生产方法。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-07-22 DOI: 10.1080/07388551.2024.2359966

Jim Junhui Huang, Wenwen Xu, Shaoling Lin, Peter Chi Keung Cheung

{"title":"The bioactivities and biotechnological production approaches of carotenoids derived from microalgae and cyanobacteria.","authors":"Jim Junhui Huang, Wenwen Xu, Shaoling Lin, Peter Chi Keung Cheung","doi":"10.1080/07388551.2024.2359966","DOIUrl":"10.1080/07388551.2024.2359966","url":null,"abstract":"Microalgae and cyanobacteria are a rich source of carotenoids that are well known for their potent bioactivities, including antioxidant, anti-cancer, anti-proliferative, anti-inflammatory, and anti-obesity properties. Recently, many interests have also been focused on the biological activities of these microalgae/cyanobacteria-derived carotenoids, such as fucoxanthin and β-carotene potential to be the salutary nutraceuticals, on treating or preventing human common diseases (e.g., cancers). This is due to their special chemical structures that demonstrate unique bioactive functions, in which the biologically active discrepancies might attribute to the different spatial configurations of their molecules. In addition, their abundance and bioaccessibilities make them more popularly applied in food and pharmaceutical industries, as compared to the macroalgal/fungal-derived ones. This review is focused on the recent studies on the bioactivities of fucoxanthin and some carotenoids derived from microalgae and cyanobacteria in relationship with human health and diseases, with emphasis on their potential applications as natural antioxidants. Various biotechnological approaches employed to induce the production of these specific carotenoids from the culture of microalgae/cyanobacteria are also critically reviewed. These well-developed and emerging biotechnologies present promise to be applied in food and pharmaceutical industries to facilitate the efficient manufacture of the bioactive carotenoid products derived from microalgae and cyanobacteria.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1-29"},"PeriodicalIF":8.1,"publicationDate":"2024-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electroactive biofilm communities in microbial fuel cells for the synergistic treatment of wastewater and bioelectricity generation. 微生物燃料电池中的电活性生物膜群落，用于协同处理废水和生物发电。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-07-15 DOI: 10.1080/07388551.2024.2372070

Kumari Uma Mahto, Surajit Das

{"title":"Electroactive biofilm communities in microbial fuel cells for the synergistic treatment of wastewater and bioelectricity generation.","authors":"Kumari Uma Mahto, Surajit Das","doi":"10.1080/07388551.2024.2372070","DOIUrl":"https://doi.org/10.1080/07388551.2024.2372070","url":null,"abstract":"Increasing industrialization and urbanization have contributed to a significant rise in wastewater discharge and exerted extensive pressure on the existing natural energy resources. Microbial fuel cell (MFC) is a sustainable technology that utilizes wastewater for electricity generation. MFC comprises a bioelectrochemical system employing electroactive biofilms of several aerobic and anaerobic bacteria, such as Geobacter sulfurreducens, Shewanella oneidensis, Pseudomonas aeruginosa, and Ochrobacterum pseudiintermedium. Since the electroactive biofilms constitute a vital part of the MFC, it is crucial to understand the biofilm-mediated pollutant metabolism and electron transfer mechanisms. Engineering electroactive biofilm communities for improved biofilm formation and extracellular polymeric substances (EPS) secretion can positively impact the bioelectrochemical system and improve fuel cell performance. This review article summarizes the role of electroactive bacterial communities in MFC for wastewater treatment and bioelectricity generation. A significant focus has been laid on understanding the composition, structure, and function of electroactive biofilms in MFC. Various electron transport mechanisms, including direct electron transfer (DET), indirect electron transfer (IET), and long-distance electron transfer (LDET), have been discussed. A detailed summary of the optimization of process parameters and genetic engineering strategies for improving the performance of MFC has been provided. Lastly, the applications of MFC for wastewater treatment, bioelectricity generation, and biosensor development have been reviewed.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1-20"},"PeriodicalIF":8.1,"publicationDate":"2024-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141619585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering microbial metabolic homeostasis for chemicals production. 为化学品生产设计微生物代谢平衡。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-07-14 DOI: 10.1080/07388551.2024.2371465

Yang Li, Mingxiong Liu, Changyang Yang, Hongxin Fu, Jufang Wang

引用次数: 0

From glycans to green biotechnology: exploring cell wall dynamics and phytobiota impact in plant glycopathology. 从聚糖到绿色生物技术：探索植物糖病理学中的细胞壁动力学和植物生物群的影响。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-07-14 DOI: 10.1080/07388551.2024.2370341

Demetrio Marcianò, Lisa Kappel, Sadia Fida Ullah, Vaibhav Srivastava

{"title":"From glycans to green biotechnology: exploring cell wall dynamics and phytobiota impact in plant glycopathology.","authors":"Demetrio Marcianò, Lisa Kappel, Sadia Fida Ullah, Vaibhav Srivastava","doi":"10.1080/07388551.2024.2370341","DOIUrl":"https://doi.org/10.1080/07388551.2024.2370341","url":null,"abstract":"Filamentous plant pathogens, including fungi and oomycetes, pose significant threats to cultivated crops, impacting agricultural productivity, quality and sustainability. Traditionally, disease control heavily relied on fungicides, but concerns about their negative impacts motivated stakeholders and government agencies to seek alternative solutions. Biocontrol agents (BCAs) have been developed as promising alternatives to minimize fungicide use. However, BCAs often exhibit inconsistent performances, undermining their efficacy as plant protection alternatives. The eukaryotic cell wall of plants and filamentous pathogens contributes significantly to their interaction with the environment and competitors. This highly adaptable and modular carbohydrate armor serves as the primary interface for communication, and the intricate interplay within this compartment is often mediated by carbohydrate-active enzymes (CAZymes) responsible for cell wall degradation and remodeling. These processes play a crucial role in the pathogenesis of plant diseases and contribute significantly to establishing both beneficial and detrimental microbiota. This review explores the interplay between cell wall dynamics and glycan interactions in the phytobiome scenario, providing holistic insights for efficiently exploiting microbial traits potentially involved in plant disease mitigation. Within this framework, the incorporation of glycobiology-related functional traits into the resident phytobiome can significantly enhance the plant's resilience to biotic stresses. Therefore, in the rational engineering of future beneficial consortia, it is imperative to recognize and leverage the understanding of cell wall interactions and the role of the glycome as an essential tool for the effective management of plant diseases.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1-19"},"PeriodicalIF":8.1,"publicationDate":"2024-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chassis engineering for high light tolerance in microalgae and cyanobacteria. 微藻类和蓝藻耐强光的底盘工程。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-07-10 DOI: 10.1080/07388551.2024.2357368

Biyun Dou, Yang Li, Fangzhong Wang, Lei Chen, Weiwen Zhang

{"title":"Chassis engineering for high light tolerance in microalgae and cyanobacteria.","authors":"Biyun Dou, Yang Li, Fangzhong Wang, Lei Chen, Weiwen Zhang","doi":"10.1080/07388551.2024.2357368","DOIUrl":"https://doi.org/10.1080/07388551.2024.2357368","url":null,"abstract":"Oxygenic photosynthesis in microalgae and cyanobacteria is considered an important chassis to accelerate energy transition and mitigate global warming. Currently, cultivation systems for photosynthetic microbes for large-scale applications encountered excessive light exposure stress. High light stress can: affect photosynthetic efficiency, reduce productivity, limit cell growth, and even cause cell death. Deciphering photoprotection mechanisms and constructing high-light tolerant chassis have been recent research focuses. In this review, we first briefly introduce the self-protection mechanisms of common microalgae and cyanobacteria in response to high light stress. These mechanisms mainly include: avoiding excess light absorption, dissipating excess excitation energy, quenching excessive high-energy electrons, ROS detoxification, and PSII repair. We focus on the species-specific differences in these mechanisms as well as recent advancements. Then, we review engineering strategies for creating high-light tolerant chassis, such as: reducing the size of the light-harvesting antenna, optimizing non-photochemical quenching, optimizing photosynthetic electron transport, and enhancing PSII repair. Finally, we propose a comprehensive exploration of mechanisms: underlying identified high light tolerant chassis, identification of new genes pertinent to high light tolerance using innovative methodologies, harnessing CRISPR systems and artificial intelligence for chassis engineering modification, and introducing plant photoprotection mechanisms as future research directions.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1-19"},"PeriodicalIF":8.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current status and future trends of microbial and nematode-based biopesticides for biocontrol of crop pathogens. 基于微生物和线虫的生物农药对作物病原体进行生物防治的现状和未来趋势。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-07-10 DOI: 10.1080/07388551.2024.2370370

Rayhane Hamrouni, Flor Regus, Anne-Marie Farnet Da Silva, Thierry Orsiere, Jean-Luc Boudenne, Isabelle Laffont-Schwob, Pierre Christen, Nathalie Dupuy

{"title":"Current status and future trends of microbial and nematode-based biopesticides for biocontrol of crop pathogens.","authors":"Rayhane Hamrouni, Flor Regus, Anne-Marie Farnet Da Silva, Thierry Orsiere, Jean-Luc Boudenne, Isabelle Laffont-Schwob, Pierre Christen, Nathalie Dupuy","doi":"10.1080/07388551.2024.2370370","DOIUrl":"https://doi.org/10.1080/07388551.2024.2370370","url":null,"abstract":"The increasing public demand to avoid the use of synthetic pesticides and fertilizers in agricultural production systems, causing serious environmental damages, has challenged industry to develop new and effective solutions to manage and control phytopathogens. Biopesticides, particularly microbial-based biopesticides, are a promising new alternative with high biodegradability, specificity, suitability for incorporation into integrated pest management practices, low likelihood of resistance development, and practically no known human health risks. However: expensive production methods, narrow action spectra, susceptibility to environmental conditions, short shelf life, poor storage stability, legislation registry constraints, and general lack of knowledge are slowing down their adoption. In addition to regulatory framework revisions and improved training initiatives, improved preservation methods, thoughtfully designed formulations, and field test validations are needed to offer new microbial- and nematode-based biopesticides with improved efficacy and increased shelf-life. During the last several years, substantial advancements in biopesticide production have been developed. The novelty part of this review written in 2023 is to summarize (i) mechanisms of action of beneficial microorganisms used to increase crop performance and (ii) successful formulation including commercial products for the biological control of phytopathogens based on microorganisms, nematode and/or metabolites.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1-20"},"PeriodicalIF":8.1,"publicationDate":"2024-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wastewater-borne viruses and bacteria, surveillance and biosensors at the interface of academia and field deployment. 废水中的病毒和细菌、学术界和实地部署之间的监控和生物传感器。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-07-07 DOI: 10.1080/07388551.2024.2354709

Rajendra Singh, Jaewon Ryu, Woo Hyoung Lee, Joo-Hyon Kang, Sanghwa Park, Keugtae Kim

{"title":"Wastewater-borne viruses and bacteria, surveillance and biosensors at the interface of academia and field deployment.","authors":"Rajendra Singh, Jaewon Ryu, Woo Hyoung Lee, Joo-Hyon Kang, Sanghwa Park, Keugtae Kim","doi":"10.1080/07388551.2024.2354709","DOIUrl":"10.1080/07388551.2024.2354709","url":null,"abstract":"Wastewater is a complex, but an ideal, matrix for disease monitoring and surveillance as it represents the entire load of enteric pathogens from a local catchment area. It captures both clinical and community disease burdens. Global interest in wastewater surveillance has been growing rapidly for infectious diseases monitoring and for providing an early warning of potential outbreaks. Although molecular detection methods show high sensitivity and specificity in pathogen monitoring from wastewater, they are strongly limited by challenges, including expensive laboratory settings and prolonged sample processing and analysis. Alternatively, biosensors exhibit a wide range of practical utility in real-time monitoring of biological and chemical markers. However, field deployment of biosensors is primarily challenged by prolonged sample processing and pathogen concentration steps due to complex wastewater matrices. This review summarizes the role of wastewater surveillance and provides an overview of infectious viral and bacterial pathogens with cutting-edge technologies for their detection. It emphasizes the practical utility of biosensors in pathogen monitoring and the major bottlenecks for wastewater surveillance of pathogens, and overcoming approaches to field deployment of biosensors for real-time pathogen detection. Furthermore, the promising potential of novel machine learning algorithms to resolve uncertainties in wastewater data is discussed.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1-21"},"PeriodicalIF":8.1,"publicationDate":"2024-07-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554368","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0