Critical Reviews in Biotechnology最新文献_第10页

Microbial alchemy: upcycling of brewery spent grains into high-value products through fermentation. 微生物炼金术：通过发酵将酿酒废弃谷物转化为高价值产品。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-11-01 Epub Date: 2024-01-01 DOI: 10.1080/07388551.2023.2286430

Vishal Ahuja, Shikha Chauhan, Sukhvinder Singh Purewal, Sanjeet Mehariya, Anil Kumar Patel, Gopalakrishnan Kumar, Mallavarapu Megharaj, Yung-Hun Yang, Shashi Kant Bhatia

{"title":"Microbial alchemy: upcycling of brewery spent grains into high-value products through fermentation.","authors":"Vishal Ahuja, Shikha Chauhan, Sukhvinder Singh Purewal, Sanjeet Mehariya, Anil Kumar Patel, Gopalakrishnan Kumar, Mallavarapu Megharaj, Yung-Hun Yang, Shashi Kant Bhatia","doi":"10.1080/07388551.2023.2286430","DOIUrl":"10.1080/07388551.2023.2286430","url":null,"abstract":"Spent grains are one of the lignocellulosic biomasses available in abundance, discarded by breweries as waste. The brewing process generates around 25-30% of waste in different forms and spent grains alone account for 80-85% of that waste, resulting in a significant global waste volume. Despite containing essential nutrients, i.e., carbohydrates, fibers, proteins, fatty acids, lipids, minerals, and vitamins, efficient and economically viable valorization of these grains is lacking. Microbial fermentation enables the valorization of spent grain biomass into numerous commercially valuable products used in energy, food, healthcare, and biomaterials. However, the process still needs more investigation to overcome challenges, such as transportation, cost-effective pretreatment, and fermentation strategy. to lower the product cost and to achieve market feasibility and customer affordability. This review summarizes the potential of spent grains valorization via microbial fermentation and associated challenges.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1367-1385"},"PeriodicalIF":8.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139073573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Every road leads to Rome: diverse biosynthetic regulation of plant cell wall-degrading enzymes in filamentous fungi Penicillium oxalicum and Trichoderma reesei. 条条大路通罗马:丝状真菌草青霉和里氏木霉中植物细胞壁降解酶的多种生物合成调控。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-11-01 Epub Date: 2023-11-30 DOI: 10.1080/07388551.2023.2280810

Shuai Zhao, Ting Zhang, Tomohisa Hasunuma, Akihiko Kondo, Xin-Qing Zhao, Jia-Xun Feng

{"title":"Every road leads to Rome: diverse biosynthetic regulation of plant cell wall-degrading enzymes in filamentous fungi Penicillium oxalicum and Trichoderma reesei.","authors":"Shuai Zhao, Ting Zhang, Tomohisa Hasunuma, Akihiko Kondo, Xin-Qing Zhao, Jia-Xun Feng","doi":"10.1080/07388551.2023.2280810","DOIUrl":"10.1080/07388551.2023.2280810","url":null,"abstract":"Cellulases and xylanases are plant cell wall-degrading enzymes (CWDEs) that are critical to sustainable bioproduction based on renewable lignocellulosic biomass to reduce carbon dioxide emission. Currently, these enzymes are mainly produced from filamentous fungi, especially Trichoderma reesei and Penicillium oxalicum. However, an in-depth comparison of these two producers has not been performed. Although both P. oxalicum and T. reesei harbor CWDE systems, they exhibit distinct features regulating the production of these enzymes, mainly through different transcriptional regulatory networks. This review presents the strikingly different modes of genome-wide regulation of cellulase and xylanase biosynthesis in P. oxalicum and T. reesei, including sugar transporters, signal transduction cascades, transcription factors, chromatin remodeling, and three-dimensional organization of chromosomes. In addition, different molecular breeding approaches employed, based on the understanding of the regulatory networks, are summarized. This review highlights the existence of very different regulatory modes leading to the efficient regulation of CWDE production in filamentous fungi, akin to the adage that \"every road leads to Rome.\" An understanding of this divergence may help further improvements in fungal enzyme production through the metabolic engineering and synthetic biology of certain fungal species.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1241-1261"},"PeriodicalIF":8.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138458393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacteriophages: a potential game changer in food processing industry. 噬菌体：食品加工业的潜在变革者。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-11-01 Epub Date: 2024-01-16 DOI: 10.1080/07388551.2023.2299768

Vandana Chaudhary, Priyanka Kajla, Deepika Lather, Nisha Chaudhary, Priya Dangi, Punit Singh, Ravi Pandiselvam

{"title":"Bacteriophages: a potential game changer in food processing industry.","authors":"Vandana Chaudhary, Priyanka Kajla, Deepika Lather, Nisha Chaudhary, Priya Dangi, Punit Singh, Ravi Pandiselvam","doi":"10.1080/07388551.2023.2299768","DOIUrl":"10.1080/07388551.2023.2299768","url":null,"abstract":"In the food industry, despite the widespread use of interventions such as preservatives and thermal and non-thermal processing technologies to improve food safety, incidences of foodborne disease continue to happen worldwide, prompting the search for alternative strategies. Bacteriophages, commonly known as phages, have emerged as a promising alternative for controlling pathogenic bacteria in food. This review emphasizes the potential applications of phages in biological sciences, food processing, and preservation, with a particular focus on their role as biocontrol agents for improving food quality and preservation. By shedding light on recent developments and future possibilities, this review highlights the significance of phages in the food industry. Additionally, it addresses crucial aspects such as regulatory status and safety concerns surrounding the use of bacteriophages. The inclusion of up-to-date literature further underscores the relevance of phage-based strategies in reducing foodborne pathogenic bacteria's presence in both food and the production environment. As we look ahead, new phage products are likely to be targeted against emerging foodborne pathogens. This will further advance the efficacy of approaches that are based on phages in maintaining the safety and security of food.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1325-1349"},"PeriodicalIF":8.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139478378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Utilizing proteomics to identify and optimize microalgae strains for high-quality dietary protein: a review. 利用蛋白质组学技术鉴定和优化微藻菌株获取优质膳食蛋白质的研究进展。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-11-01 Epub Date: 2023-11-30 DOI: 10.1080/07388551.2023.2283376

Sara Hamzelou, Damien Belobrajdic, James A Broadbent, Angéla Juhász, Kim Lee Chang, Ian Jameson, Peter Ralph, Michelle L Colgrave

引用次数: 0

Global regulator IrrE on stress tolerance: a review. 关于抗逆性的全球调控因子 IrrE：综述。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-11-01 Epub Date: 2024-01-21 DOI: 10.1080/07388551.2023.2299766

Li Wang, Yong-Shui Tan, Kai Chen, Samuel Ntakirutimana, Zhi-Hua Liu, Bing-Zhi Li, Ying-Jin Yuan

{"title":"Global regulator IrrE on stress tolerance: a review.","authors":"Li Wang, Yong-Shui Tan, Kai Chen, Samuel Ntakirutimana, Zhi-Hua Liu, Bing-Zhi Li, Ying-Jin Yuan","doi":"10.1080/07388551.2023.2299766","DOIUrl":"10.1080/07388551.2023.2299766","url":null,"abstract":"Stress tolerance is a vital attribute for all living beings to cope with environmental adversities. IrrE (also named PprI) from Deinococcus radiodurans enhances resistance to extreme radiation stress by functioning as a global regulator, mediating the transcription of genes involved in deoxyribonucleic acid (DNA) damage response (DDR). The expression of IrrE augmented the resilience of various species to heat, radiation, oxidation, osmotic stresses and inhibitors, encompassing bacterial, fungal, plant, and mammalian cells. Moreover, IrrE was employed in a global regulator engineering strategy to broaden its applications in stress tolerance. The regulatory impacts of heterologously expressed IrrE have been investigated at the molecular and systems level, including the regulation of genes, proteins, modules, or pathways involved in DNA repair, detoxification proteins, protective molecules, native regulators and other aspects. In this review, we discuss the regulatory role and mechanism of IrrE in the antiradiation response of D. radiodurans. Furthermore, the applications and regulatory effects of heterologous expression of IrrE to enhance abiotic stress tolerance are summarized in particular.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1439-1459"},"PeriodicalIF":8.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139512046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ascorbic acid: a metabolite switch for designing stress-smart crops. 抗坏血酸：设计抗逆作物的代谢开关。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-11-01 Epub Date: 2024-01-01 DOI: 10.1080/07388551.2023.2286428

Shefali Mishra, Ankush Sharma, Ashish Kumar Srivastava

{"title":"Ascorbic acid: a metabolite switch for designing stress-smart crops.","authors":"Shefali Mishra, Ankush Sharma, Ashish Kumar Srivastava","doi":"10.1080/07388551.2023.2286428","DOIUrl":"10.1080/07388551.2023.2286428","url":null,"abstract":"Plant growth and productivity are continually being challenged by a diverse array of abiotic stresses, including: water scarcity, extreme temperatures, heavy metal exposure, and soil salinity. A common theme in these stresses is the overproduction of reactive oxygen species (ROS), which disrupts cellular redox homeostasis causing oxidative damage. Ascorbic acid (AsA), commonly known as vitamin C, is an essential nutrient for humans, and also plays a crucial role in the plant kingdom. AsA is synthesized by plants through the d-mannose/l-galactose pathway that functions as a powerful antioxidant and protects plant cells from ROS generated during photosynthesis. AsA controls several key physiological processes, including: photosynthesis, respiration, and carbohydrate metabolism, either by acting as a co-factor for metabolic enzymes or by regulating cellular redox-status. AsA's multi-functionality uniquely positions it to integrate and recalibrate redox-responsive transcriptional/metabolic circuits and essential biological processes, in accordance to developmental and environmental cues. In recognition of this, we present a systematic overview of current evidence highlighting AsA as a central metabolite-switch in plants. Further, a comprehensive overview of genetic manipulation of genes involved in AsA metabolism has been provided along with the bottlenecks and future research directions, that could serve as a framework for designing \"stress-smart\" crops in future.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1350-1366"},"PeriodicalIF":8.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139073572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in high-throughput screening approaches for biosurfactants: current trends, bottlenecks and perspectives. 生物表面活性剂高通量筛选方法的进展：当前趋势、瓶颈和前景。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-11-01 Epub Date: 2024-01-17 DOI: 10.1080/07388551.2023.2290981

Muneer Ahmed Qazi, Irfan Ali Phulpoto, Qinhong Wang, Zongjie Dai

{"title":"Advances in high-throughput screening approaches for biosurfactants: current trends, bottlenecks and perspectives.","authors":"Muneer Ahmed Qazi, Irfan Ali Phulpoto, Qinhong Wang, Zongjie Dai","doi":"10.1080/07388551.2023.2290981","DOIUrl":"10.1080/07388551.2023.2290981","url":null,"abstract":"The market size of biosurfactants (BSs) has been expanding at an extremely fast pace due to their broad application scope. Therefore, the re-construction of cell factories with modified genomic and metabolic profiles for desired industrial performance has been an intriguing aspect. Typical mutagenesis approaches generate huge mutant libraries, whereas a battery of specific, robust, and cost-effective high-throughput screening (HTS) methods is requisite to screen target strains for desired phenotypes. So far, only a few specialized HTS assays have been developed for BSs that were successfully applied to obtain anticipated mutants. The most important milestones to reach, however, continue to be: specificity, sensitivity, throughput, and the potential for automation. Here, we discuss important colorimetric and fluorometric HTS approaches for possible intervention on automated HTS platforms. Moreover, we explain current bottlenecks in developing specialized HTS platforms for screening high-yielding producers and discuss possible perspectives for addressing such challenges.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"1403-1421"},"PeriodicalIF":8.1,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139485388","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Potential anti-aging applications of microbial-derived surfactantsin cosmetic formulations. 微生物衍生表面活性剂在化妆品配方中的潜在抗衰老应用。

IF 9 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-09-18 DOI: 10.1080/07388551.2024.2393420

Amir Mohammad Bagheri,Masoud Mirzahashemi,Soodeh Salarpour,Yasmin Dehghnnoudeh,Ibrahim M Banat,Mandana Ohadi,Gholamreza Dehghannoudeh

{"title":"Potential anti-aging applications of microbial-derived surfactantsin cosmetic formulations.","authors":"Amir Mohammad Bagheri,Masoud Mirzahashemi,Soodeh Salarpour,Yasmin Dehghnnoudeh,Ibrahim M Banat,Mandana Ohadi,Gholamreza Dehghannoudeh","doi":"10.1080/07388551.2024.2393420","DOIUrl":"https://doi.org/10.1080/07388551.2024.2393420","url":null,"abstract":"The skin aging process is a complex interaction of genetic, epigenetic, and environmental factors, such as chemical pollution and UV radiation. There is growing evidence that biosurfactants, especially those of microbial origin, have distinct age-supportive effects through different mechanisms, such as stimulation of fibroblast growth, high antioxidant capacities, and favorable anti-inflammatory properties. With a growing financial contribution of more than 15 m€per year, microbial surfactants (MSs) display unique biological effects on the skin including improved cell mobility, better nutrient access, and facilitated cellular growth under harsh conditions. Their biodegradable nature, unusual surface activity, good safety profile and tolerance to high temperature and pH variations widen their potential spectrum in biomedical and pharmaceutical applications. MSs typically have lower critical micelle concentration (CMC) levels than chemical surfactants enhancing their effectiveness. As natural surfactants, MSs are considered possible \"green\" alternatives to synthetic surfactants with better biodegradability, sustainability, and beneficial functional properties. This review therefore aims to explore the potential impacts of MSs as anti-aging ingredients.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":"29 1","pages":"1-22"},"PeriodicalIF":9.0,"publicationDate":"2024-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142268669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in microbial production of geraniol: from metabolic engineering to potential industrial applications. 微生物生产香叶醇的进展：从代谢工程到潜在的工业应用。

IF 9 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-09-12 DOI: 10.1080/07388551.2024.2391881

Xun Wang,Xinyi Zhang,Jia Zhang,Yujunjie Zhou,Fei Wang,Zhiguo Wang,Xun Li

{"title":"Advances in microbial production of geraniol: from metabolic engineering to potential industrial applications.","authors":"Xun Wang,Xinyi Zhang,Jia Zhang,Yujunjie Zhou,Fei Wang,Zhiguo Wang,Xun Li","doi":"10.1080/07388551.2024.2391881","DOIUrl":"https://doi.org/10.1080/07388551.2024.2391881","url":null,"abstract":"Geraniol, an acyclic monoterpene alcohol, has significant potential applications in various fields, including: food, cosmetics, biofuels, and pharmaceuticals. However, the current sources of geraniol mainly include plant tissue extraction or chemical synthesis, which are unsustainable and suffer severely from high energy consumption and severe environmental problems. The process of microbial production of geraniol has recently undergone vigorous development. Particularly, the sustainable construction of recombinant Escherichia coli (13.2 g/L) and Saccharomyces cerevisiae (5.5 g/L) laid a solid foundation for the microbial production of geraniol. In this review, recent advances in the development of geraniol-producing strains, including: metabolic pathway construction, key enzyme improvement, genetic modification strategies, and cytotoxicity alleviation, are critically summarized. Furthermore, the key challenges in scaling up geraniol production and future perspectives for the development of robust geraniol-producing strains are suggested. This review provides theoretical guidance for the industrial production of geraniol using microbial cell factories.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":"19 1","pages":"1-16"},"PeriodicalIF":9.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Advances in metabolic engineering for enhanced acetyl-CoA availability in yeast. 提高酵母乙酰-CoA 利用率的代谢工程研究进展。

IF 9 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2024-09-12 DOI: 10.1080/07388551.2024.2399542

Yuanyuan Sha,Mianshen Ge,Minrui Lu,Zhaoxian Xu,Rui Zhai,Mingjie Jin

{"title":"Advances in metabolic engineering for enhanced acetyl-CoA availability in yeast.","authors":"Yuanyuan Sha,Mianshen Ge,Minrui Lu,Zhaoxian Xu,Rui Zhai,Mingjie Jin","doi":"10.1080/07388551.2024.2399542","DOIUrl":"https://doi.org/10.1080/07388551.2024.2399542","url":null,"abstract":"Acetyl-CoA is an intermediate metabolite in cellular central metabolism. It's a precursor for various valuable commercial products, including: terpenoids, fatty acids, and polyketides. With the advancement of metabolic and synthetic biology tools, microbial cell factories have been constructed for the efficient synthesis of acetyl-CoA and derivatives, with the Saccharomyces cerevisiae and Yarrowia lipolytica as two prominent chassis. This review summarized the recent developments in the biosynthetic pathways and metabolic engineering approaches for acetyl-CoA and its derivatives synthesis in these two yeasts. First, the metabolic routes involved in the biosynthesis of acetyl-CoA and derived products were outlined. Then, the advancements in metabolic engineering strategies for channeling acetyl-CoA toward the desired products were summarized, with particular emphasis on: enhancing metabolic flux in different organelles, refining precursor CoA synthesis, optimizing substrate utilization, and modifying protein acetylation level. Finally, future developments in advancing the metabolic engineering strategies for acetyl-CoA and related derivatives synthesis, including: reducing CO2 emissions, dynamically regulating metabolic pathways, and exploring the regulatory functions between acetyl-CoA levels and protein acetylation, are highlighted. This review provided new insights into regulating acetyl-CoA synthesis to create more effective microbial cell factories for bio-manufacturing.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":"192 1","pages":"1-19"},"PeriodicalIF":9.0,"publicationDate":"2024-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142252374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0