Critical Reviews in Biotechnology最新文献_第8页

Lignocellulosic materials valorization in second generation biorefineries: an opportunity to produce fungal biopigments. 第二代生物炼油厂中木质纤维素材料的增值：生产真菌生物颜料的机会。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-05-30 DOI: 10.1080/07388551.2024.2349581

Gabriel L Arruda, Maria Teresa F R Raymundo, Mónica M Cruz-Santos, Vinícius P Shibukawa, Fanny M Jofre, Carina A Prado, Silvio S da Silva, Solange I Mussatto, Júlio C Santos

{"title":"Lignocellulosic materials valorization in second generation biorefineries: an opportunity to produce fungal biopigments.","authors":"Gabriel L Arruda, Maria Teresa F R Raymundo, Mónica M Cruz-Santos, Vinícius P Shibukawa, Fanny M Jofre, Carina A Prado, Silvio S da Silva, Solange I Mussatto, Júlio C Santos","doi":"10.1080/07388551.2024.2349581","DOIUrl":"10.1080/07388551.2024.2349581","url":null,"abstract":"Second generation biorefineries play an important role in the production of renewable energy and fuels, utilizing forest and agro-industrial residues and by-products as raw materials. The integration of novel bioproducts, such as: xylitol, β-carotene, xylooligosaccharides, and biopigments into the biorefinery's portfolio can offer economic benefits in the valorization of lignocellulosic materials, particularly cellulosic and hemicellulosic fractions. Fungal biopigments, known for their additional antioxidant and antimicrobial properties, are appealing to consumers and can have applications in various industrial sectors, including food and pharmaceuticals. The use of lignocellulosic materials as carbon and nutrient sources for the growth medium helps to reduce production costs, increasing the competitiveness of fungal biopigments in the market. In addition, the implementation of biopigment production in biorefineries allows the utilization of underutilized fractions, such as hemicellulose, for value-added bioproducts. This study deals with the potential of fungal biopigments production in second generation biorefineries in order to diversify the produced biomolecules together with energy generation. A comprehensive and critical review of the recent literature on this topic has been conducted, covering the major possible raw materials, general aspects of second generation biorefineries, the fungal biopigments and their potential for incorporation into biorefineries.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"393-412"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

D-allulose 3-epimerase for low-calorie D-allulose synthesis: microbial production, characterization, and applications. 用于低热量 D-纤维素合成的 D-allulose 3-epimerase：微生物生产、表征和应用。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-07-07 DOI: 10.1080/07388551.2024.2368517

Xiaofang Xie, Caiming Li, Xiaofeng Ban, Hongshun Yang, Zhaofeng Li

{"title":"D-allulose 3-epimerase for low-calorie D-allulose synthesis: microbial production, characterization, and applications.","authors":"Xiaofang Xie, Caiming Li, Xiaofeng Ban, Hongshun Yang, Zhaofeng Li","doi":"10.1080/07388551.2024.2368517","DOIUrl":"10.1080/07388551.2024.2368517","url":null,"abstract":"D-allulose, an epimer of D-fructose at C-3 position, is a low-calorie rare sugar with favorable physiochemical properties and special physiological functions, which displays promising perspectives in the food and pharmaceutical industries. Currently, D-allulose is extremely sparse in nature and is predominantly biosynthesized through the isomerization of D-fructose by D-allulose 3-epimerase (DAEase). In recent years, D-allulose 3-epimerase as the key biocatalyst for D-allulose production has received increasing interest. The current review begins by providing a summary of D-allulose regarding its characteristics and applications, as well as different synthesis pathways dominated by biotransformation. Then, the research advances of D-allulose 3-epimerase are systematically reviewed, focusing on heterologous expression and biochemical characterization, crystal structure and molecular modification, and application in D-allulose production. Concerning the constraint of low yield of DAEase for industrial application, this review addresses the various attempts made to promote the production of DAEase in different expression systems. Also, various strategies have been adopted to improve its thermotolerance and catalytic activity, which is mainly based on the structure-function relationship of DAEase. The application of DAEase in D-allulose biosynthesis from D-fructose or low-cost feedstocks through single- or multi-enzymatic cascade reaction has been discussed. Finally, the prospects for related research of D-allulose 3-epimerase are also proposed, facilitating the industrialization of DAEase and more efficient and economical bioproduction of D-allulose.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"353-372"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141554367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-05-08 DOI: 10.1080/07388551.2024.2344583

Talha Javed, Wenzhi Wang, Benpeng Yang, Linbo Shen, Tingting Sun, San-Ji Gao, Shuzhen Zhang

{"title":"Pathogenesis related-1 proteins in plant defense: regulation and functional diversity.","authors":"Talha Javed, Wenzhi Wang, Benpeng Yang, Linbo Shen, Tingting Sun, San-Ji Gao, Shuzhen Zhang","doi":"10.1080/07388551.2024.2344583","DOIUrl":"10.1080/07388551.2024.2344583","url":null,"abstract":"Climate change-related environmental stresses can negatively impact crop productivity and pose a threat to sustainable agriculture. Plants have a remarkable innate ability to detect a broad array of environmental cues, including stresses that trigger stress-induced regulatory networks and signaling pathways. Transcriptional activation of plant pathogenesis related-1 (PR-1) proteins was first identified as an integral component of systemic acquired resistance in response to stress. Consistent with their central role in immune defense, overexpression of PR-1s in diverse plant species is frequently used as a marker for salicylic acid (SA)-mediated defense responses. Recent advances demonstrated how virulence effectors, SA signaling cascades, and epigenetic modifications modulate PR-1 expression in response to environmental stresses. We and others showed that transcriptional regulatory networks involving PR-1s could be used to improve plant resilience to stress. Together, the results of these studies have re-energized the field and provided long-awaited insights into a possible function of PR-1s under extreme environmental stress.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"305-313"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The bioactivities and biotechnological production approaches of carotenoids derived from microalgae and cyanobacteria. 从微藻和蓝藻中提取的类胡萝卜素的生物活性和生物技术生产方法。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-07-22 DOI: 10.1080/07388551.2024.2359966

Jim Junhui Huang, Wenwen Xu, Shaoling Lin, Peter Chi Keung Cheung

{"title":"The bioactivities and biotechnological production approaches of carotenoids derived from microalgae and cyanobacteria.","authors":"Jim Junhui Huang, Wenwen Xu, Shaoling Lin, Peter Chi Keung Cheung","doi":"10.1080/07388551.2024.2359966","DOIUrl":"10.1080/07388551.2024.2359966","url":null,"abstract":"Microalgae and cyanobacteria are a rich source of carotenoids that are well known for their potent bioactivities, including antioxidant, anti-cancer, anti-proliferative, anti-inflammatory, and anti-obesity properties. Recently, many interests have also been focused on the biological activities of these microalgae/cyanobacteria-derived carotenoids, such as fucoxanthin and β-carotene potential to be the salutary nutraceuticals, on treating or preventing human common diseases (e.g., cancers). This is due to their special chemical structures that demonstrate unique bioactive functions, in which the biologically active discrepancies might attribute to the different spatial configurations of their molecules. In addition, their abundance and bioaccessibilities make them more popularly applied in food and pharmaceutical industries, as compared to the macroalgal/fungal-derived ones. This review is focused on the recent studies on the bioactivities of fucoxanthin and some carotenoids derived from microalgae and cyanobacteria in relationship with human health and diseases, with emphasis on their potential applications as natural antioxidants. Various biotechnological approaches employed to induce the production of these specific carotenoids from the culture of microalgae/cyanobacteria are also critically reviewed. These well-developed and emerging biotechnologies present promise to be applied in food and pharmaceutical industries to facilitate the efficient manufacture of the bioactive carotenoid products derived from microalgae and cyanobacteria.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"276-304"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141747617","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A close-up of regulatory networks and signaling pathways of MKK5 in biotic and abiotic stresses. MKK5在生物和非生物胁迫中的调控网络和信号通路特写。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-05-26 DOI: 10.1080/07388551.2024.2344584

Ali Movahedi, Delight Hwarari, Raphael Dzinyela, Siyi Ni, Liming Yang

{"title":"A close-up of regulatory networks and signaling pathways of MKK5 in biotic and abiotic stresses.","authors":"Ali Movahedi, Delight Hwarari, Raphael Dzinyela, Siyi Ni, Liming Yang","doi":"10.1080/07388551.2024.2344584","DOIUrl":"10.1080/07388551.2024.2344584","url":null,"abstract":"Mitogen-activated protein Kinase Kinase 5 (MKK5) is a central hub in the complex phosphorylation chain reaction of the Mitogen-activated protein kinases (MAPK) cascade, regulating plant responses to biotic and abiotic stresses. This review manuscript aims to provide a comprehensive analysis of the regulatory mechanism of the MKK5 involved in stress adaptation. This review will delve into the intricate post-transcriptional and post-translational modifications of the MKK5, discussing how they affect its expression, activity, and subcellular localization in response to stress signals. We also discuss the integration of the MKK5 into complex signaling pathways, orchestrating plant immunity against pathogens and its modulating role in regulating abiotic stresses, such as: drought, cold, heat, and salinity, through the phytohormonal signaling pathways. Furthermore, we highlight potential applications of the MKK5 for engineering stress-resilient crops and provide future perspectives that may pave the way for future studies. This review manuscript aims to provide valuable insights into the mechanisms underlying MKK5 regulation, bridge the gap from numerous previous findings, and offer a firm base in the knowledge of MKK5, its regulating roles, and its involvement in environmental stress regulation.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"473-490"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma. 深入研究 Phaffia rhodozyma 虾青素生物合成代谢机制的新策略。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-05-26 DOI: 10.1080/07388551.2024.2344578

Zhipeng Li, Li You, Xiping Du, Haoyi Yang, Liang Yang, Yanbing Zhu, Lijun Li, Zedong Jiang, Qingbiao Li, Ning He, Rui Lin, Zhen Chen, Hui Ni

{"title":"New strategies to study in depth the metabolic mechanism of astaxanthin biosynthesis in Phaffia rhodozyma.","authors":"Zhipeng Li, Li You, Xiping Du, Haoyi Yang, Liang Yang, Yanbing Zhu, Lijun Li, Zedong Jiang, Qingbiao Li, Ning He, Rui Lin, Zhen Chen, Hui Ni","doi":"10.1080/07388551.2024.2344578","DOIUrl":"10.1080/07388551.2024.2344578","url":null,"abstract":"Astaxanthin, a ketone carotenoid known for its high antioxidant activity, holds significant potential for application in nutraceuticals, aquaculture, and cosmetics. The increasing market demand necessitates a higher production of astaxanthin using Phaffia rhodozyma. Despite extensive research efforts focused on optimizing fermentation conditions, employing mutagenesis treatments, and utilizing genetic engineering technologies to enhance astaxanthin yield in P. rhodozyma, progress in this area remains limited. This review provides a comprehensive summary of the current understanding of rough metabolic pathways, regulatory mechanisms, and preliminary strategies for enhancing astaxanthin yield. However, further investigation is required to fully comprehend the intricate and essential metabolic regulation mechanism underlying astaxanthin synthesis. Specifically, the specific functions of key genes, such as crtYB, crtS, and crtI, need to be explored in detail. Additionally, a thorough understanding of the action mechanism of bifunctional enzymes and alternative splicing products is imperative. Lastly, the regulation of metabolic flux must be thoroughly investigated to reveal the complete pathway of astaxanthin synthesis. To obtain an in-depth mechanism and improve the yield of astaxanthin, this review proposes some frontier methods, including: omics, genome editing, protein structure-activity analysis, and synthetic biology. Moreover, it further elucidates the feasibility of new strategies using these advanced methods in various effectively combined ways to resolve these problems mentioned above. This review provides theory and method for studying the metabolic pathway of astaxanthin in P. rhodozyma and the industrial improvement of astaxanthin, and provides new insights into the flexible combined use of multiple modern advanced biotechnologies.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"454-472"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Current status and future trends of microbial and nematode-based biopesticides for biocontrol of crop pathogens. 基于微生物和线虫的生物农药对作物病原体进行生物防治的现状和未来趋势。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-07-10 DOI: 10.1080/07388551.2024.2370370

Rayhane Hamrouni, Flor Regus, Anne-Marie Farnet Da Silva, Thierry Orsiere, Jean-Luc Boudenne, Isabelle Laffont-Schwob, Pierre Christen, Nathalie Dupuy

{"title":"Current status and future trends of microbial and nematode-based biopesticides for biocontrol of crop pathogens.","authors":"Rayhane Hamrouni, Flor Regus, Anne-Marie Farnet Da Silva, Thierry Orsiere, Jean-Luc Boudenne, Isabelle Laffont-Schwob, Pierre Christen, Nathalie Dupuy","doi":"10.1080/07388551.2024.2370370","DOIUrl":"10.1080/07388551.2024.2370370","url":null,"abstract":"The increasing public demand to avoid the use of synthetic pesticides and fertilizers in agricultural production systems, causing serious environmental damages, has challenged industry to develop new and effective solutions to manage and control phytopathogens. Biopesticides, particularly microbial-based biopesticides, are a promising new alternative with high biodegradability, specificity, suitability for incorporation into integrated pest management practices, low likelihood of resistance development, and practically no known human health risks. However: expensive production methods, narrow action spectra, susceptibility to environmental conditions, short shelf life, poor storage stability, legislation registry constraints, and general lack of knowledge are slowing down their adoption. In addition to regulatory framework revisions and improved training initiatives, improved preservation methods, thoughtfully designed formulations, and field test validations are needed to offer new microbial- and nematode-based biopesticides with improved efficacy and increased shelf-life. During the last several years, substantial advancements in biopesticide production have been developed. The novelty part of this review written in 2023 is to summarize (i) mechanisms of action of beneficial microorganisms used to increase crop performance and (ii) successful formulation including commercial products for the biological control of phytopathogens based on microorganisms, nematode and/or metabolites.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"333-352"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141579221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Engineering microbial metabolic homeostasis for chemicals production. 为化学品生产设计微生物代谢平衡。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-07-14 DOI: 10.1080/07388551.2024.2371465

Yang Li, Mingxiong Liu, Changyang Yang, Hongxin Fu, Jufang Wang

引用次数: 0

From glycans to green biotechnology: exploring cell wall dynamics and phytobiota impact in plant glycopathology. 从聚糖到绿色生物技术：探索植物糖病理学中的细胞壁动力学和植物生物群的影响。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-03-01 Epub Date: 2024-07-14 DOI: 10.1080/07388551.2024.2370341

Demetrio Marcianò, Lisa Kappel, Sadia Fida Ullah, Vaibhav Srivastava

{"title":"From glycans to green biotechnology: exploring cell wall dynamics and phytobiota impact in plant glycopathology.","authors":"Demetrio Marcianò, Lisa Kappel, Sadia Fida Ullah, Vaibhav Srivastava","doi":"10.1080/07388551.2024.2370341","DOIUrl":"10.1080/07388551.2024.2370341","url":null,"abstract":"Filamentous plant pathogens, including fungi and oomycetes, pose significant threats to cultivated crops, impacting agricultural productivity, quality and sustainability. Traditionally, disease control heavily relied on fungicides, but concerns about their negative impacts motivated stakeholders and government agencies to seek alternative solutions. Biocontrol agents (BCAs) have been developed as promising alternatives to minimize fungicide use. However, BCAs often exhibit inconsistent performances, undermining their efficacy as plant protection alternatives. The eukaryotic cell wall of plants and filamentous pathogens contributes significantly to their interaction with the environment and competitors. This highly adaptable and modular carbohydrate armor serves as the primary interface for communication, and the intricate interplay within this compartment is often mediated by carbohydrate-active enzymes (CAZymes) responsible for cell wall degradation and remodeling. These processes play a crucial role in the pathogenesis of plant diseases and contribute significantly to establishing both beneficial and detrimental microbiota. This review explores the interplay between cell wall dynamics and glycan interactions in the phytobiome scenario, providing holistic insights for efficiently exploiting microbial traits potentially involved in plant disease mitigation. Within this framework, the incorporation of glycobiology-related functional traits into the resident phytobiome can significantly enhance the plant's resilience to biotic stresses. Therefore, in the rational engineering of future beneficial consortia, it is imperative to recognize and leverage the understanding of cell wall interactions and the role of the glycome as an essential tool for the effective management of plant diseases.","PeriodicalId":10752,"journal":{"name":"Critical Reviews in Biotechnology","volume":" ","pages":"314-332"},"PeriodicalIF":8.1,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141616037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Food contamination from packaging material with special focus on the Bisphenol-A. 包装材料对食品的污染，特别关注双酚 A。

IF 8.1 2区工程技术

Critical Reviews in Biotechnology Pub Date : 2025-02-01 Epub Date: 2024-06-05 DOI: 10.1080/07388551.2024.2344571

Aparna Agarwal, Shivika Gandhi, Abhishek Dutt Tripathi, Abhishek Gupta, Marco Iammarino, Jaisal Kaur Sidhu

引用次数: 0